Aging alters long-term potentiation-related gene networks and impairs synaptic protein synthesis in the rat hippocampus

Neurobiology of Aging

Volumn 36, Issue 5, 2015, Pages 1868-1880

  Ryan, Margaret M ^a   Guévremont, Diane ^a   Luxmanan, Carthika ^a,b   Abraham, Wickliffe C ^a   Williams, Joanna M ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b Pacific Edge Ltd   (New Zealand)

Author keywords

Ingenuity pathway analysis; Microarray; Synaptic protein synthesis; Transcription factors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IONOTROPIC RECEPTOR; MEMBRANE PROTEIN; METABOTROPIC RECEPTOR; SYNAPTIC PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; NERVE PROTEIN;

ADULT; AGE DISTRIBUTION; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DNA MICROARRAY; EPIGENETICS; GENE EXPRESSION; GENETIC REGULATION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MIDDLE AGED; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS REGULATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REFERENCE MEMORY; SIGNAL TRANSDUCTION; WORKING MEMORY; ANIMAL; BIOLOGY; BIOSYNTHESIS; GENETIC EPIGENESIS; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT; SYNAPSE;

AGING; ANIMALS; COMPUTATIONAL BIOLOGY; EPIGENESIS, GENETIC; GENE EXPRESSION; LONG-TERM POTENTIATION; MALE; NERVE TISSUE PROTEINS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS; RATS, SPRAGUE-DAWLEY; SYNAPSES; TRANSCRIPTION FACTOR AP-1;

EID: 84933178849     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.01.012     Document Type: Article

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