The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 70, Issue 12, 2015, Pages 1499-1507

  Le Couteur, David G ^a,b,c   Tay, Szun S ^d   Solon Biet, Samantha ^a,b,c   Bertolino, Patrick ^d   McMahon, Aisling C ^a,b,c   Cogger, Victoria C ^a,b,c   Colakoglu, Feyza ^a   Warren, Alessandra ^a,b,c   Holmes, Andrew J ^a   Pichaud, Nicolas ^e   Horan, Martin ^e   Correa, Carolina ^e   Melvin, Richard G ^f   Turner, Nigel ^e   O Ballard, J William ^e   Ruohonen, Kari ^g   Raubenheimer, David ^a,c,h   Simpson, Stephen J ^a,c  

^a University of Sydney   (Australia)

^b Department of Microbiology and Infectious Diseases   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

^f UNIVERSITY OF HELSINKI   (Finland)

^g CARGILL INC   (United States)

^h Faculty of Veterinary Science   (Australia)

Author keywords

Liver; Lymphocytes; Macronutrients

Indexed keywords

CARBOHYDRATE DIET; FAT INTAKE; PROTEIN INTAKE;

AGE; ANIMAL; C57BL MOUSE; CARBOHYDRATE DIET; DRUG EFFECTS; FAT INTAKE; FEMALE; IMMUNOLOGY; LIVER; LYMPHOCYTE; MALE; MOUSE; PHARMACOLOGY; PROTEIN INTAKE; VISCERA;

AGE FACTORS; ANIMALS; DIETARY CARBOHYDRATES; DIETARY FATS; DIETARY PROTEINS; FEMALE; LIVER; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; VISCERA;

EID: 84957793070     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu196     Document Type: Article

References (42)

1. Fernandes G. Nutritional factors: modulating effects on immune function and aging. Pharmacol Rev. 1984;36(2 suppl):123S-129S.
2. Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology. 2007;120:435-446.
3. Cevenini E, Monti D, Franceschi C. Infamm-ageing. Curr Opin Clin Nutr Metab Care. 2013;16:14-20.
4. Wang L, Xie Y, Zhu LJ, Chang TT, Mao YQ, Li J. An association between immunosenescence and CD4(+)CD25(+) regulatory T cells: a systematic review. Biomed Environ Sci. 2010;23:327-332.
5. Callahan JE, Kappler JW, Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J Immunol. 1993;151:6657-6669.
6. Fernandes G, Venkatraman JT, Turturro A, Attwood VG, Hart RW. Effect of food restriction on life span and immune functions in long-lived Fis-cher-344 x Brown Norway F1 rats. J Clin Immunol. 1997;17:85-95.
7. Reddy Avula CP, Muthukumar A, Fernandes G. Calorie restriction increases Fas/Fas-ligand expression and apoptosis in murine splenic lymphocytes. FEBS Lett. 1999;458:231-235.
8. Harper JM, Galecki AT, Burke DT, Miller RA. Body weight, hormones and T cell subsets as predictors of life span in genetically heterogeneous mice. Mech Ageing Dev. 2004;125:381-390.
9. Miller RA, Chrisp C, Galecki A. CD4 memory T cell levels predict life span in genetically heterogeneous mice. FASEB J. 1997;11:775-783.
10. Miller RA. Biomarkers of aging: prediction of longevity by using age-sensitive T-cell subset determinations in a middle-aged, genetically heterogeneous mouse population. J Gerontol A Biol Sci Med Sci. 2001;56:B180-B186.
11. Sun D, Krishnan A, Su J, Lawrence R, Zaman K, Fernandes G. Regulation of immune function by calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice. Cell Immunol. 2004;228: 54-65.
12. Lustig A, Carter A, Bertak D, et al. Transcriptome analysis of murine thy-mocytes reveals age-associated changes in thymic gene expression. Int J Med Sci. 2009;6:51-64.
13. Franceschi C, Capri M, Monti D, et al. Infammaging and anti-infammag-ing: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev. 2007;128:92-105.
14. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996;273:59-63.
15. Everitt AV, Rattan SI, Le Couteur DG, de Cabo R, eds. (2010). Calorie Restriction, Aging and Longevity. New York, NY: Springer Press.
16. Speakman JR, Mitchell SE. Caloric restriction. Mol Aspects Med. 2011;32:159-221.
17. Fernandes G, Yunis EJ, Good RA. Infuence of protein restriction on immune functions in NZB mice. J Immunol. 1976;116:782-790.
18. Fernandes G, Friend P, Yunis EJ, Good RA. Infuence of dietary restriction on immunologic function and renal disease in (NZB x NZW) F1 mice. Proc Natl Acad Sci USA. 1978;75:1500-1504.
19. Troyer DA, Venkatraman JT, Fernandes G. Effects of calorie restriction and ω-3 dietary fat on aging in short-and long-lived rodents. Age (Omaha). 1998;21:175-182.
20. Simpson SJ, Raubenheimer D. Caloric restriction and aging revisited: the need for a geometric analysis of the nutritional bases of aging. J Gerontol A Biol Sci Med Sci. 2007;62:707-713.
21. Simpson SJ, Raubenheimer D. Macronutrient balance and lifespan. Aging (Albany NY). 2009;1:875-880.
22. Piper MD, Partridge L, Raubenheimer D, Simpson SJ. Dietary restriction and aging: a unifying perspective. Cell Metab. 2011;14:154-160.
23. Solon-Biet S, McMahon A, Ballard JWO, et al. The ratio of macronutri-ents, not caloric intake, dictates cardiometabolic health, aging and longevity in ad libitum-fed mice. Cell Metab. 2014;19:418-430.
24. Le Couteur DG, Wilder SM, de Cabo R, Simpson SJ. The evolution of research on ageing and nutrition. J Gerontol A Biol Sci Med Sci. 2014;69:1-2.
25. Simpson SJ, Raubenheimer D. Obesity: the protein leverage hypothesis. Obes Rev. 2005;6:133-142.
26. Sørensen A, Mayntz D, Raubenheimer D, Simpson SJ. Protein-leverage in mice: the geometry of macronutrient balancing and consequences for fat deposition. Obesity (Silver Spring). 2008;16:566-571.
27. Lee K P, Simpson SJ, Clissold FJ, et al. Lifespan and reproduction in Dros-ophila: New insights from nutritional geometry. Proc Natl Acad Sci USA. 2008;105:2498-2503.
28. Fanson BG, Weldon CW, Pérez-Staples D, Simpson SJ, Taylor PW. Nutrients, not caloric restriction, extend lifespan in Queensland fruit fies (Bac-trocera tryoni). Aging Cell. 2009;8:514-523.
29. Simpson SJ, Raubenheimer D. The Nature of Nutrition. A Unifying Framework form Animal Adaption to Human Obesity. Princeton, NJ: Princeton University Press; 2012.
30. Horan MP, Pichaud N, Ballard JWO. Quantifying mitochondrial dysfunction in complex diseases of ageing. J Gerontol Biol Sci Med Sci. 2012;67:1022-1035.
31. Xiong X, Wang X, Lu Y, et al. Hepatic steatosis exacerbated by endoplas-mic reticulum stress-mediated downregulation of FXR in aging mice. J Hepatol. 2014;60:847-854.
32. Franko A, von Kleist-Retzow JC, Neschen S, et al. Liver adapts mitochon-drial function to insulin resistant and diabetic states in mice. J Hepatol. 2014;60:816-823.
33. Walford RL, Liu RK, Gerbase-Delima M, Mathies M, Smith GS. Longterm dietary restriction and immune function in mice: response to sheep red blood cells and to mitogenic agents. Mech Ageing Dev. 1973;2:447-454.
34. Weindruch RH, Kristie JA, Cheney KE, Walford RL. Infuence of controlled dietary restriction on immunologic function and aging. Fed Proc. 1979;38:2007-2016.
35. Grossmann A, Maggio-Price L, Jinneman JC, Wolf NS, Rabinovitch PS. The effect of long-term caloric restriction on function of T-cell subsets in old mice. Cell Immunol. 1990;131:191-204.
36. Le Couteur DG, Fraser R, Cogger VC, McLean AJ. Hepatic pseudocapil-larisation and atherosclerosis in ageing. Lancet. 2002;359:1612-1615.
37. Le Couteur DG, Sinclair DA, Cogger VC, et al. The ageing liver and longterm caloric restriction. In: Everitt A, Rattan S, Le Couteur DG, de Cabo R. Calorie Restriction, Aging and Longevity. Dordrecht: Springer Press; 2010:191-216.
38. Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev. 1994;74:121-133.
39. Mougiakakos D, Johansson CC, Kiessling R. Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress-induced cell death. Blood. 2009;113:3542-3545.
40. Mougiakakos D, Johansson CC, Jitschin R, Böttcher M, Kiessling R. Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress. Blood. 2011;117:857-861.
41. Ma X, Hua J, Mohamood AR, Hamad AR, Ravi R, Li Z. A high-fat diet and regulatory T cells infuence susceptibility to endotoxin-induced liver injury. Hepatology. 2007;46:1519-1529.
42. Gao B, Radaeva S, Park O. Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases. J Leukoc Biol. 2009;86:513-528.