Toward rapamycin analog (rapalog)-based precision cancer therapy

Acta Pharmacologica Sinica

Volumn 36, Issue 10, 2015, Pages 1163-1169

  Meng, Ling Hua ^a,b   Zheng, Xf Steven ^a  

^a RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

mTOR; precision cancer therapy; rapalog; rapamycin

Indexed keywords

BEVACIZUMAB; CETUXIMAB; DALOTUZUMAB; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; NAVELBINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; RAPAMYCIN DERIVATIVE; RIDAFOROLIMUS; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TRAMETINIB; TRASTUZUMAB; ANTINEOPLASTIC ANTIBIOTIC; TARGET OF RAPAMYCIN KINASE;

ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER IMMUNOTHERAPY; CANCER PATIENT; CANCER THERAPY; DRUG EFFICACY; DRUG TOLERABILITY; FUNCTIONAL GENOMICS; HUMAN; IMMUNOMODULATION; MONOTHERAPY; NEXT GENERATION SEQUENCING; NONHUMAN; PANCREATIC NEUROENDOCRINE TUMOR; REVIEW; RNA INTERFERENCE; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; ANIMAL; BIOLOGY; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOLECULARLY TARGETED THERAPY; NEOPLASMS; PERSONALIZED MEDICINE; PROCEDURES; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; COMPUTATIONAL BIOLOGY; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PRECISION MEDICINE; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84943270672     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.68     Document Type: Review

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