-
1
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor, R. R., Gao, S., Zhai, P., Zablocki, D., Holle, E., Yu, X., et al. (2007). Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ. Res. 100, 1512-1521. doi: 10.1161/01.res.0000267723.65696.4a
-
(2007)
Circ. Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zablocki, D.4
Holle, E.5
Yu, X.6
-
2
-
-
0038329323
-
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
-
Anderson, R. M., Bitterman, K. J., Wood, J. G., Medvedik, O., and Sinclair, D. A. (2003). Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423, 181-185. doi: 10.1038/nature01578
-
(2003)
Nature
, vol.423
, pp. 181-185
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Sinclair, D.A.5
-
3
-
-
47749140333
-
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
-
Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., et al. (2008). SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 134, 317-328. doi: 10.1016/j.cell.2008.06.050
-
(2008)
Cell
, vol.134
, pp. 317-328
-
-
Asher, G.1
Gatfield, D.2
Stratmann, M.3
Reinke, H.4
Dibner, C.5
Kreppel, F.6
-
4
-
-
79952747862
-
Alzheimer's disease
-
Ballard, C., Gauthier, S., Corbett, A., Brayne, C., Aarsland, D., and Jones, E. (2011). Alzheimer's disease. Lancet 377, 1019-1031. doi: 10.1016/S0140-6736(10)61349-9
-
(2011)
Lancet
, vol.377
, pp. 1019-1031
-
-
Ballard, C.1
Gauthier, S.2
Corbett, A.3
Brayne, C.4
Aarsland, D.5
Jones, E.6
-
5
-
-
36749037180
-
Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease
-
Bandyopadhyay, S., Goldstein, L. E., Lahiri, D. K., and Rogers, J. T. (2007). Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease. Curr. Med. Chem. 14, 2848-2864. doi: 10.2174/092986707782360060
-
(2007)
Curr. Med. Chem
, vol.14
, pp. 2848-2864
-
-
Bandyopadhyay, S.1
Goldstein, L.E.2
Lahiri, D.K.3
Rogers, J.T.4
-
6
-
-
84886743585
-
Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer
-
Baptista, T., Graça, I., Sousa, E. J., Oliveira, A. I., Costa, N. R., Costa-Pinheiro, P., et al. (2013). Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer. Oncotarget 4, 1673-1685.
-
(2013)
Oncotarget
, vol.4
, pp. 1673-1685
-
-
Baptista, T.1
Graça, I.2
Sousa, E.J.3
Oliveira, A.I.4
Costa, N.R.5
Costa-Pinheiro, P.6
-
7
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., et al. (2006). Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342. doi: 10.1038/nature05354
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
-
8
-
-
84861852370
-
Are sirtuins viable targets for improving healthspan and lifespan?
-
Baur, J. A., Ungvari, Z., Minor, R. K., Le Couteur, D. G., and de Cabo, R. (2012). Are sirtuins viable targets for improving healthspan and lifespan? Nat. Rev. Drug Discov. 11, 443-461. doi: 10.1038/nrd3738
-
(2012)
Nat. Rev. Drug Discov
, vol.11
, pp. 443-461
-
-
Baur, J.A.1
Ungvari, Z.2
Minor, R.K.3
Le Couteur, D.G.4
de Cabo, R.5
-
9
-
-
77950229880
-
Neural mechanisms of ageing and cognitive decline
-
Bishop, N. A., Lu, T., and Yankner, B. A. (2010). Neural mechanisms of ageing and cognitive decline. Nature 464, 529-535. doi: 10.1038/nature08983
-
(2010)
Nature
, vol.464
, pp. 529-535
-
-
Bishop, N.A.1
Lu, T.2
Yankner, B.A.3
-
10
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander, G., and Guarente, L. (2004). The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73, 417-435. doi: 10.1146/annurev.biochem.73.011303.073651
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
11
-
-
79951686964
-
The sirtuin pathway in ageing and Alzheimer disease: Mechanistic and therapeutic considerations
-
Bonda, D. J., Lee, H. G., Camins, A., Pallàs, M., Casadesus, G., Smith, M. A., et al. (2011). The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol. 10, 275-279. doi: 10.1016/s1474-4422(11)70013-8
-
(2011)
Lancet Neurol
, vol.10
, pp. 275-279
-
-
Bonda, D.J.1
Lee, H.G.2
Camins, A.3
Pallàs, M.4
Casadesus, G.5
Smith, M.A.6
-
12
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
-
Bordone, L., Motta, M. C., Picard, F., Robinson, A., Jhala, U. S., Apfeld, J., et al. (2006). Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol. 4:e31. doi: 10.1371/journal.pbio.0040031
-
(2006)
PLoS Biol
, vol.4
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
Robinson, A.4
Jhala, U.S.5
Apfeld, J.6
-
13
-
-
84859429591
-
Sirtuins in cognitive ageing and Alzheimer's disease
-
Braidy, N., Jayasena, T., Poljak, A., and Sachdev, P. S. (2012). Sirtuins in cognitive ageing and Alzheimer's disease. Curr. Opin. Psychiatry 25, 226-230. doi: 10.1097/YCO.0b013e32835112c1
-
(2012)
Curr. Opin. Psychiatry
, vol.25
, pp. 226-230
-
-
Braidy, N.1
Jayasena, T.2
Poljak, A.3
Sachdev, P.S.4
-
14
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., et al. (2004). Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015. doi: 10.1126/science.1094637
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
-
15
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett, C., Valentini, S., Cabreiro, F., Goss, M., Somogyvári, M., Piper, M. D., et al. (2011). Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477, 482-485. doi: 10.1038/nature10296
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvári, M.5
Piper, M.D.6
-
16
-
-
0036430355
-
Aging gracefully: Compensatory brain activity in high-performing older adults
-
Cabeza, R., Anderson, N. D., Locantore, J. K., and McIntosh, A. R. (2002). Aging gracefully: compensatory brain activity in high-performing older adults. Neuroimage 17, 1394-1402. doi: 10.1006/nimg.2002.1280
-
(2002)
Neuroimage
, vol.17
, pp. 1394-1402
-
-
Cabeza, R.1
Anderson, N.D.2
Locantore, J.K.3
McIntosh, A.R.4
-
17
-
-
77949506721
-
Hypothalamic Sirt1 regulates food intake in a rodent model system
-
Cakir, I., Perello, M., Lansari, O., Messier, N. J., Vaslet, C. A., and Nillni, E. A. (2009). Hypothalamic Sirt1 regulates food intake in a rodent model system. PLoS One 4:e8322. doi: 10.1371/journal.pone.0008322
-
(2009)
PLoS One
, vol.4
-
-
Cakir, I.1
Perello, M.2
Lansari, O.3
Messier, N.J.4
Vaslet, C.A.5
Nillni, E.A.6
-
18
-
-
69849107217
-
Caloric restriction, SIRT1 and longevity
-
Cantó, C., and Auwerx, J. (2009a). Caloric restriction, SIRT1 and longevity. Trends Endocrinol. Metab. 20, 325-331. doi: 10.1016/j.tem.2009.03.008
-
(2009)
Trends Endocrinol. Metab
, vol.20
, pp. 325-331
-
-
Cantó, C.1
Auwerx, J.2
-
19
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Cantó, C., and Auwerx, J. (2009b). PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr. Opin. Lipidol. 20, 98-105. doi: 10.1097/MOL.0b013e328328d0a4
-
(2009)
Curr. Opin. Lipidol
, vol.20
, pp. 98-105
-
-
Cantó, C.1
Auwerx, J.2
-
20
-
-
84878550919
-
Sirtuins family-recent development as a drug target for aging, metabolism and age related diseases
-
Chakraborty, C., and Doss, C. G. P. (2013). Sirtuins family-recent development as a drug target for aging, metabolism and age related diseases. Curr. Drug Targets 14, 666-675. doi: 10.2174/1389450111314060008
-
(2013)
Curr. Drug Targets
, vol.14
, pp. 666-675
-
-
Chakraborty, C.1
Doss, C.G.P.2
-
21
-
-
84859977895
-
Sirtuins mediate mammalian metabolic responses to nutrient availability
-
Chalkiadaki, A., and Guarente, L. (2012). Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat. Rev. Endocrinol. 8, 287-296. doi: 10.1038/nrendo.2011.225
-
(2012)
Nat. Rev. Endocrinol
, vol.8
, pp. 287-296
-
-
Chalkiadaki, A.1
Guarente, L.2
-
22
-
-
84879391795
-
SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
-
Chang, H. C., and Guarente, L. (2013). SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 153, 1448-1460. doi: 10.1016/j.cell.2013.05.027
-
(2013)
Cell
, vol.153
, pp. 1448-1460
-
-
Chang, H.C.1
Guarente, L.2
-
23
-
-
84894352303
-
SIRT1 and other sirtuins in metabolism
-
Chang, H. C., and Guarente, L. (2014). SIRT1 and other sirtuins in metabolism. Trends Endocrinol. Metab. 25, 138-145. doi: 10.1016/j.tem.2013.12.001
-
(2014)
Trends Endocrinol. Metab
, vol.25
, pp. 138-145
-
-
Chang, H.C.1
Guarente, L.2
-
24
-
-
68049134459
-
Metabolic benefits from Sirt1 and Sirt1 activators
-
Chaudhary, N., and Pfluger, P. T. (2009). Metabolic benefits from Sirt1 and Sirt1 activators. Curr. Opin. Clin. Nutr. Metab. Care 12, 431-437. doi: 10.1097/MCO.0b013e32832cdaae
-
(2009)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.12
, pp. 431-437
-
-
Chaudhary, N.1
Pfluger, P.T.2
-
25
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-κB signaling
-
Chen, J., Zhou, Y., Mueller-Steiner, S., Chen, L. F., Kwon, H., Yi, S., et al. (2005). SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-κB signaling. J. Biol. Chem. 280, 40364-40374. doi: 10.1074/jbc.m509329200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
-
26
-
-
84920937355
-
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β
-
Cho, S. H., Chen, J. A., Sayed, F., Ward, M. E., Gao, F., Nguyen, T. A., et al. (2015). SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β. J. Neurosci. 35, 807-818. doi: 10.1523/JNEUROSCI.2939-14.2015
-
(2015)
J. Neurosci
, vol.35
, pp. 807-818
-
-
Cho, S.H.1
Chen, J.A.2
Sayed, F.3
Ward, M.E.4
Gao, F.5
Nguyen, T.A.6
-
27
-
-
84883462446
-
Recent advances in calorie restriction research on aging
-
Chung, K. W., Kim, D. H., Park, M. H., Choi, Y. J., Kim, N. D., Lee, J., et al. (2013). Recent advances in calorie restriction research on aging. Exp. Gerontol. 48, 1049-1053. doi: 10.1016/j.exger.2012.11.007
-
(2013)
Exp. Gerontol
, vol.48
, pp. 1049-1053
-
-
Chung, K.W.1
Kim, D.H.2
Park, M.H.3
Choi, Y.J.4
Kim, N.D.5
Lee, J.6
-
28
-
-
84867131638
-
SIRT1 regulates dendritic development in hippocampal neurons
-
Codocedo, J. F., Allard, C., Godoy, J. A., Varela-Nallar, L., and Inestrosa, N. C. (2012). SIRT1 regulates dendritic development in hippocampal neurons. PLoS One 7:e47073. doi: 10.1371/journal.pone.0047073
-
(2012)
PLoS One
, vol.7
-
-
Codocedo, J.F.1
Allard, C.2
Godoy, J.A.3
Varela-Nallar, L.4
Inestrosa, N.C.5
-
29
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen, H. Y., Miller, C., Bitterman, K. J., Wall, N. R., Hekking, B., Kessler, B., et al. (2004). Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305, 390-392. doi: 10.1126/science.1099196
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
-
30
-
-
72849130743
-
Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
-
Cohen, D. E., Supinski, A. M., Bonkowski, M. S., Donmez, G., and Guarente, L. P. (2009). Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev. 23, 2812-2817. doi: 10.1101/gad.1839209
-
(2009)
Genes Dev
, vol.23
, pp. 2812-2817
-
-
Cohen, D.E.1
Supinski, A.M.2
Bonkowski, M.S.3
Donmez, G.4
Guarente, L.P.5
-
31
-
-
84862230016
-
sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury
-
Corrigan, F., Vink, R., Blumbergs, P. C., Masters, C. L., Cappai, R., and van den Heuvel, C. (2012). sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury. J. Neurochem. 122, 208-220. doi: 10.1111/j.1471-4159.2012.07761.x
-
(2012)
J. Neurochem
, vol.122
, pp. 208-220
-
-
Corrigan, F.1
Vink, R.2
Blumbergs, P.C.3
Masters, C.L.4
Cappai, R.5
van den Heuvel, C.6
-
32
-
-
84903269902
-
Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats
-
Cyr, N. E., Steger, J. S., Toorie, A. M., Yang, J. Z., Stuart, R., and Nillni, E. A. (2014). Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats. Endocrinology 155, 2423-2435. doi: 10.1210/en.2013-1998
-
(2014)
Endocrinology
, vol.155
, pp. 2423-2435
-
-
Cyr, N.E.1
Steger, J.S.2
Toorie, A.M.3
Yang, J.Z.4
Stuart, R.5
Nillni, E.A.6
-
33
-
-
77956241193
-
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: Roles for Sirt1 in neuronal firing and synaptic plasticity
-
Dietrich, M. O., Antunes, C., Geliang, G., Liu, Z. W., Borok, E., Nie, Y., et al. (2010). Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. J. Neurosci. 30, 11815-11825. doi: 10.1523/JNEUROSCI.2234-10.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 11815-11825
-
-
Dietrich, M.O.1
Antunes, C.2
Geliang, G.3
Liu, Z.W.4
Borok, E.5
Nie, Y.6
-
34
-
-
84880921439
-
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons
-
Dobbin, M. M., Madabhushi, R., Pan, L., Chen, Y., Kim, D., Gao, J., et al. (2013). SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons. Nat. Neurosci. 16, 1008-1015. doi: 10.1038/nn.3460
-
(2013)
Nat. Neurosci
, vol.16
, pp. 1008-1015
-
-
Dobbin, M.M.1
Madabhushi, R.2
Pan, L.3
Chen, Y.4
Kim, D.5
Gao, J.6
-
35
-
-
84855929223
-
SIRT1 protects against α-synuclein aggregation by activating molecular chaperones
-
Donmez, G., Arun, A., Chung, C. Y., McLean, P. J., Lindquist, S., and Guarente, L. (2012). SIRT1 protects against α-synuclein aggregation by activating molecular chaperones. J. Neurosci. 32, 124-132. doi: 10.1523/JNEUROSCI.3442-11.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 124-132
-
-
Donmez, G.1
Arun, A.2
Chung, C.Y.3
McLean, P.J.4
Lindquist, S.5
Guarente, L.6
-
36
-
-
84874709843
-
SIRT1 and SIRT2: Emerging targets in neurodegeneration
-
Donmez, G., and Outeiro, T. F. (2013). SIRT1 and SIRT2: emerging targets in neurodegeneration. EMBO Mol. Med. 5, 344-352. doi: 10.1002/emmm.201302451
-
(2013)
EMBO Mol. Med
, vol.5
, pp. 344-352
-
-
Donmez, G.1
Outeiro, T.F.2
-
37
-
-
77955046461
-
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
-
Donmez, G., Wang, D., Cohen, D. E., and Guarente, L. (2010). SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142, 320-332. doi: 10.1016/j.cell.2010.06.020
-
(2010)
Cell
, vol.142
, pp. 320-332
-
-
Donmez, G.1
Wang, D.2
Cohen, D.E.3
Guarente, L.4
-
38
-
-
27744596999
-
Sir2 blocks extreme life-span extension
-
Fabrizio, P., Gattazzo, C., Battistella, L., Wei, M., Cheng, C., McGrew, K., et al. (2005). Sir2 blocks extreme life-span extension. Cell 123, 655-667. doi: 10.1016/j.cell.2005.08.042
-
(2005)
Cell
, vol.123
, pp. 655-667
-
-
Fabrizio, P.1
Gattazzo, C.2
Battistella, L.3
Wei, M.4
Cheng, C.5
McGrew, K.6
-
39
-
-
84868109139
-
Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus
-
Falone, S., D'Alessandro, A., Mirabilio, A., Cacchio, M., Di Ilio, C., Di Loreto, S., et al. (2012). Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus. PLoS One 7:e48334. doi: 10.1371/journal.pone.0048334
-
(2012)
PLoS One
, vol.7
-
-
Falone, S.1
D'Alessandro, A.2
Mirabilio, A.3
Cacchio, M.4
Di Ilio, C.5
Di Loreto, S.6
-
40
-
-
41549136422
-
Paths of convergence: Sirtuins in aging and neurodegeneration
-
Gan, L., and Mucke, L. (2008). Paths of convergence: sirtuins in aging and neurodegeneration. Neuron 58, 10-14. doi: 10.1016/j.neuron.2008.03.015
-
(2008)
Neuron
, vol.58
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
41
-
-
77956185062
-
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
-
Gao, J., Wang, W. Y., Mao, Y. W., Gräff, J., Guan, J. S., Pan, L., et al. (2010). A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466, 1105-1109. doi: 10.1038/nature09271
-
(2010)
Nature
, vol.466
, pp. 1105-1109
-
-
Gao, J.1
Wang, W.Y.2
Mao, Y.W.3
Gräff, J.4
Guan, J.S.5
Pan, L.6
-
42
-
-
84872224226
-
The potential of HDAC inhibitors as cognitive enhancers
-
Gräff, J., and Tsai, L. H. (2013). The potential of HDAC inhibitors as cognitive enhancers. Annu. Rev. Pharmacol. Toxicol. 53, 311-330. doi: 10.1146/annurev-pharmtox-011112-140216
-
(2013)
Annu. Rev. Pharmacol. Toxicol
, vol.53
, pp. 311-330
-
-
Gräff, J.1
Tsai, L.H.2
-
43
-
-
58149267462
-
Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau
-
Green, K. N., Steffan, J. S., Martinez-Coria, H., Sun, X., Schreiber, S. S., Thompson, L. M., et al. (2008). Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J. Neurosci. 28, 11500-11510. doi: 10.1523/JNEUROSCI.3203-08.2008
-
(2008)
J. Neurosci
, vol.28
, pp. 11500-11510
-
-
Green, K.N.1
Steffan, J.S.2
Martinez-Coria, H.3
Sun, X.4
Schreiber, S.S.5
Thompson, L.M.6
-
44
-
-
84885355365
-
Calorie restriction and sirtuins revisited
-
Guarente, L. (2013). Calorie restriction and sirtuins revisited. Genes Dev. 27, 2072-2085. doi: 10.1101/gad.227439.113
-
(2013)
Genes Dev
, vol.27
, pp. 2072-2085
-
-
Guarente, L.1
-
45
-
-
80052645243
-
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling
-
Guo, W., Qian, L., Zhang, J., Zhang, W., Morrison, A., Hayes, P., et al. (2011). Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling. J. Neurosci. Res. 89, 1723-1736. doi: 10.1002/jnr.22725
-
(2011)
J. Neurosci. Res
, vol.89
, pp. 1723-1736
-
-
Guo, W.1
Qian, L.2
Zhang, J.3
Zhang, W.4
Morrison, A.5
Hayes, P.6
-
46
-
-
80054047383
-
The role of MeCP2 in the brain
-
Guy, J., Cheval, H., Selfridge, J., and Bird, A. (2011). The role of MeCP2 in the brain. Annu. Rev. Cell Dev. Biol. 27, 631-652. doi: 10.1146/annurev-cellbio-092910-154121
-
(2011)
Annu. Rev. Cell Dev. Biol
, vol.27
, pp. 631-652
-
-
Guy, J.1
Cheval, H.2
Selfridge, J.3
Bird, A.4
-
47
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis, M. C., and Sinclair, D. A. (2010). Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 5, 253-295. doi: 10.1146/annurev.pathol.4.110807.092250
-
(2010)
Annu. Rev. Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
48
-
-
52049096152
-
Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons
-
Hasegawa, K., and Yoshikawa, K. (2008). Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J. Neurosci. 28, 8772-8784. doi: 10.1523/JNEUROSCI.3052-08.2008
-
(2008)
J. Neurosci
, vol.28
, pp. 8772-8784
-
-
Hasegawa, K.1
Yoshikawa, K.2
-
49
-
-
84885076245
-
Impact of apolipoprotein E on Alzheimer's disease
-
Hauser, P. S., and Ryan, R. O. (2013). Impact of apolipoprotein E on Alzheimer's disease. Curr. Alzheimer Res. 10, 809-817. doi: 10.2174/15672050113109990156
-
(2013)
Curr. Alzheimer Res
, vol.10
, pp. 809-817
-
-
Hauser, P.S.1
Ryan, R.O.2
-
50
-
-
84922149440
-
SIRT1 suppresses the senescence-associated secretory phenotype through epigenetic gene regulation
-
Hayakawa, T., Iwai, M., Aoki, S., Takimoto, K., Maruyama, M., Maruyama, W., et al. (2015). SIRT1 suppresses the senescence-associated secretory phenotype through epigenetic gene regulation. PLoS One 10:e0116480. doi: 10.1371/journal.pone.0116480
-
(2015)
PLoS One
, vol.10
-
-
Hayakawa, T.1
Iwai, M.2
Aoki, S.3
Takimoto, K.4
Maruyama, M.5
Maruyama, W.6
-
51
-
-
84880790329
-
Silent information regulator 1 protects the brain against cerebral ischemic damage
-
Hernández-Jiménez, M., Hurtado, O., Cuartero, M. I., Ballesteros, I., Moraga, A., Pradillo, J. M., et al. (2013). Silent information regulator 1 protects the brain against cerebral ischemic damage. Stroke 44, 2333-2337. doi: 10.1161/STROKEAHA.113.001715
-
(2013)
Stroke
, vol.44
, pp. 2333-2337
-
-
Hernández-Jiménez, M.1
Hurtado, O.2
Cuartero, M.I.3
Ballesteros, I.4
Moraga, A.5
Pradillo, J.M.6
-
52
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz, D., Muñoz-Martin, M., Cañamero, M., Mulero, F., Martinez-Pastor, B., Fernandez-Capetillo, O., et al. (2010). Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat. Commun. 1:3. doi: 10.1038/ncomms1001
-
(2010)
Nat. Commun
, vol.1
, pp. 3
-
-
Herranz, D.1
Muñoz-Martin, M.2
Cañamero, M.3
Mulero, F.4
Martinez-Pastor, B.5
Fernandez-Capetillo, O.6
-
53
-
-
84893459319
-
SIRT1 in neurodevelopment and brain senescence
-
Herskovits, A. Z., and Guarente, L. (2014). SIRT1 in neurodevelopment and brain senescence. Neuron 81, 471-483. doi: 10.1016/j.neuron.2014.01.028
-
(2014)
Neuron
, vol.81
, pp. 471-483
-
-
Herskovits, A.Z.1
Guarente, L.2
-
54
-
-
84863091207
-
Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression
-
Heyward, F. D., Walton, R. G., Carle, M. S., Coleman, M. A., Garvey, W. T., and Sweatt, J. D. (2012). Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression. Neurobiol. Learn. Mem. 98, 25-32. doi: 10.1016/j.nlm.2012.04.005
-
(2012)
Neurobiol. Learn. Mem
, vol.98
, pp. 25-32
-
-
Heyward, F.D.1
Walton, R.G.2
Carle, M.S.3
Coleman, M.A.4
Garvey, W.T.5
Sweatt, J.D.6
-
55
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey, M. D., Shimazu, T., Goetzman, E., Jing, E., Schwer, B., Lombard, D. B., et al. (2010). SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 464, 121-125. doi: 10.1038/nature08778
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
-
56
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang, H., and Tindall, D. J. (2007). Dynamic FoxO transcription factors. J. Cell Sci. 120, 2479-2487. doi: 10.1242/jcs.001222
-
(2007)
J. Cell Sci
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
57
-
-
79951844222
-
Role of Pax3 acetylation in the regulation of Hes1 and Neurog2
-
Ichi, S., Boshnjaku, V., Shen, Y. W., Mania-Farnell, B., Ahlgren, S., Sapru, S., et al. (2011). Role of Pax3 acetylation in the regulation of Hes1 and Neurog2. Mol. Biol. Cell 22, 503-512. doi: 10.1091/mbc.e10-06-0541
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 503-512
-
-
Ichi, S.1
Boshnjaku, V.2
Shen, Y.W.3
Mania-Farnell, B.4
Ahlgren, S.5
Sapru, S.6
-
58
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai, S., Armstrong, C. M., Kaeberlein, M., and Guarente, L. (2000). Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403, 795-800. doi: 10.1038/35001622
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
59
-
-
84855563516
-
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
-
Jeong, H., Cohen, D. E., Cui, L., Supinski, A., Savas, J. N., Mazzulli, J. R., et al. (2011). Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nat. Med. 18, 159-165. doi: 10.1038/nm.2559
-
(2011)
Nat. Med
, vol.18
, pp. 159-165
-
-
Jeong, H.1
Cohen, D.E.2
Cui, L.3
Supinski, A.4
Savas, J.N.5
Mazzulli, J.R.6
-
60
-
-
84855544817
-
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
-
Jiang, M., Wang, J., Fu, J., Du, L., Jeong, H., West, T., et al. (2011). Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat. Med. 18, 153-158. doi: 10.1038/nm.2558
-
(2011)
Nat. Med
, vol.18
, pp. 153-158
-
-
Jiang, M.1
Wang, J.2
Fu, J.3
Du, L.4
Jeong, H.5
West, T.6
-
61
-
-
64049092736
-
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
-
Julien, C., Tremblay, C., Emond, V., Lebbadi, M., Salem, N., Bennett, D. A., et al. (2009). Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease. J. Neuropathol. Exp. Neurol. 68, 48-58. doi: 10.1097/NEN.0b013e3181922348
-
(2009)
J. Neuropathol. Exp. Neurol
, vol.68
, pp. 48-58
-
-
Julien, C.1
Tremblay, C.2
Emond, V.3
Lebbadi, M.4
Salem, N.5
Bennett, D.A.6
-
62
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein, M., McVey, M., and Guarente, L. (1999). The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13, 2570-2580. doi: 10.1101/gad.13.19.2570
-
(1999)
Genes Dev
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
63
-
-
34347354447
-
Sir2 and calorie restriction in yeast: A skeptical perspective
-
Kaeberlein, M., and Powers, R. W. (2007). Sir2 and calorie restriction in yeast: a skeptical perspective. Ageing Res. Rev. 6, 128-140. doi: 10.1016/j.arr.2007.04.001
-
(2007)
Ageing Res. Rev
, vol.6
, pp. 128-140
-
-
Kaeberlein, M.1
Powers, R.W.2
-
64
-
-
68549085061
-
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection
-
Kakefuda, K., Fujita, Y., Oyagi, A., Hyakkoku, K., Kojima, T., Umemura, K., et al. (2009). Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. Biochem. Biophys. Res. Commun. 387, 784-788. doi: 10.1016/j.bbrc.2009.07.119
-
(2009)
Biochem. Biophys. Res. Commun
, vol.387
, pp. 784-788
-
-
Kakefuda, K.1
Fujita, Y.2
Oyagi, A.3
Hyakkoku, K.4
Kojima, T.5
Umemura, K.6
-
65
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi, Y., Naiman, S., Amir, G., Peshti, V., Zinman, G., Nahum, L., et al. (2012). The sirtuin SIRT6 regulates lifespan in male mice. Nature 483, 218-221. doi: 10.1038/nature10815
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
-
66
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim, D., Nguyen, M. D., Dobbin, M. M., Fischer, A., Sananbenesi, F., Rodgers, J. T., et al. (2007). SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 26, 3169-3179. doi: 10.1038/sj.emboj.7601758
-
(2007)
EMBO J
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
-
67
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura, K. D., Tissenbaum, H. A., Liu, Y., and Ruvkun, G. (1997). daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946. doi: 10.1126/science.277.5328.942
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
68
-
-
80755168947
-
Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats
-
Knight, C. M., Gutierrez-Juarez, R., Lam, T. K. T., Arrieta-Cruz, I., Huang, L., Schwartz, G., et al. (2011). Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes 60, 2691-2700. doi: 10.2337/db10-0987
-
(2011)
Diabetes
, vol.60
, pp. 2691-2700
-
-
Knight, C.M.1
Gutierrez-Juarez, R.2
Lam, T.K.T.3
Arrieta-Cruz, I.4
Huang, L.5
Schwartz, G.6
-
69
-
-
78651365099
-
Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice
-
Kurata, T., Miyazaki, K., Kozuki, M., Panin, V. L., Morimoto, N., Ohta, Y., et al. (2011). Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice. Brain Res. 1371, 161-170. doi: 10.1016/j.brainres.2010.11.067
-
(2011)
Brain Res
, vol.1371
, pp. 161-170
-
-
Kurata, T.1
Miyazaki, K.2
Kozuki, M.3
Panin, V.L.4
Morimoto, N.5
Ohta, Y.6
-
70
-
-
0141526319
-
Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases
-
Kyrylenko, S., Kyrylenko, O., Suuronen, T., and Salminen, A. (2003). Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases. Cell. Mol. Life Sci. 60, 1990-1997. doi: 10.1007/s00018-003-3090-z
-
(2003)
Cell. Mol. Life Sci
, vol.60
, pp. 1990-1997
-
-
Kyrylenko, S.1
Kyrylenko, O.2
Suuronen, T.3
Salminen, A.4
-
71
-
-
84883510170
-
The role of sirtuins in Alzheimer's disease
-
Lalla, R., and Donmez, G. (2013). The role of sirtuins in Alzheimer's disease. Front. Aging Neurosci. 5:16. doi: 10.3389/fnagi.2013.00016
-
(2013)
Front. Aging Neurosci
, vol.5
, pp. 16
-
-
Lalla, R.1
Donmez, G.2
-
72
-
-
84886993387
-
SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation
-
Laurent, G., de Boer, V. C. J., Finley, L. W. S., Sweeney, M., Lu, H., Schug, T. T., et al. (2013a). SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation. Mol. Cell. Biol. 33, 4552-4561. doi: 10.1128/MCB.00087-13
-
(2013)
Mol. Cell. Biol
, vol.33
, pp. 4552-4561
-
-
Laurent, G.1
de Boer, V.C.J.2
Finley, L.W.S.3
Sweeney, M.4
Lu, H.5
Schug, T.T.6
-
73
-
-
84878891625
-
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase
-
Laurent, G., German, N. J., Saha, A. K., de Boer, V. C. J., Davies, M., Koves, T. R., et al. (2013b). SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol. Cell 50, 686-698. doi: 10.1016/j.molcel.2013.05.012
-
(2013)
Mol. Cell
, vol.50
, pp. 686-698
-
-
Laurent, G.1
German, N.J.2
Saha, A.K.3
de Boer, V.C.J.4
Davies, M.5
Koves, T.R.6
-
74
-
-
84906319574
-
Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β
-
Lee, H. R., Shin, H. K., Park, S. Y., Kim, H. Y., Lee, W. S., Rhim, B. Y., et al. (2014). Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β. J. Neurosci. Res. 92, 1581-1590. doi: 10.1002/jnr.23421
-
(2014)
J. Neurosci. Res
, vol.92
, pp. 1581-1590
-
-
Lee, H.R.1
Shin, H.K.2
Park, S.Y.3
Kim, H.Y.4
Lee, W.S.5
Rhim, B.Y.6
-
75
-
-
84871782815
-
SIRT1 and energy metabolism
-
Li, X. (2013). SIRT1 and energy metabolism. Acta Biochim. Biophys. Sin. (Shanghai) 45, 51-60. doi: 10.1093/abbs/gms108
-
(2013)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.45
, pp. 51-60
-
-
Li, X.1
-
76
-
-
84888004300
-
Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3
-
Li, X. H., Chen, C., Tu, Y., Sun, H. T., Zhao, M. L., Cheng, S. X., et al. (2013). Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3. Mol. Neurobiol. 48, 490-499. doi: 10.1007/s12035-013-8437-3
-
(2013)
Mol. Neurobiol
, vol.48
, pp. 490-499
-
-
Li, X.H.1
Chen, C.2
Tu, Y.3
Sun, H.T.4
Zhao, M.L.5
Cheng, S.X.6
-
77
-
-
45549096918
-
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
-
Li, Y., Xu, W., McBurney, M. W., and Longo, V. D. (2008). SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab. 8, 38-48. doi: 10.1016/j.cmet.2008.05.004
-
(2008)
Cell Metab
, vol.8
, pp. 38-48
-
-
Li, Y.1
Xu, W.2
McBurney, M.W.3
Longo, V.D.4
-
78
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin, S. J., Defossez, P. A., and Guarente, L. (2000). Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289, 2126-2128. doi: 10.1126/science.289.5487.2126
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
79
-
-
84866556460
-
Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein
-
Liu, L., Arun, A., Ellis, L., Peritore, C., and Donmez, G. (2012). Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein. J. Biol. Chem. 287, 32307-32311. doi: 10.1074/jbc.c112.403048
-
(2012)
J. Biol. Chem
, vol.287
, pp. 32307-32311
-
-
Liu, L.1
Arun, A.2
Ellis, L.3
Peritore, C.4
Donmez, G.5
-
80
-
-
65249173918
-
Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons
-
Liu, D., Gharavi, R., Pitta, M., Gleichmann, M., and Mattson, M. P. (2009). Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons. Neuromolecular Med. 11, 28-42. doi: 10.1007/s12017-009-8058-1
-
(2009)
Neuromolecular Med
, vol.11
, pp. 28-42
-
-
Liu, D.1
Gharavi, R.2
Pitta, M.3
Gleichmann, M.4
Mattson, M.P.5
-
81
-
-
84901236321
-
SIRT1 knockdown promotes neural differentiation and attenuates the heat shock response
-
Liu, D. J., Hammer, D., Komlos, D., Chen, K. Y., Firestein, B. L., and Liu, A. Y. C. (2014). SIRT1 knockdown promotes neural differentiation and attenuates the heat shock response. J. Cell. Physiol. 229, 1224-1235. doi: 10.1002/jcp.24556
-
(2014)
J. Cell. Physiol
, vol.229
, pp. 1224-1235
-
-
Liu, D.J.1
Hammer, D.2
Komlos, D.3
Chen, K.Y.4
Firestein, B.L.5
Liu, A.Y.C.6
-
82
-
-
84879747965
-
MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration
-
Liu, C. M., Wang, R. Y., Saijilafu, Jiao, Z. X., Zhang, B. Y., and Zhou, F. Q. (2013a). MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration. Genes Dev. 27, 1473-1483. doi: 10.1101/gad.209619.112
-
(2013)
Genes Dev
, vol.27
, pp. 1473-1483
-
-
Liu, C.M.1
Wang, R.Y.2
Saijilafu, J.Z.X.3
Zhang, B.Y.4
Zhou, F.Q.5
-
83
-
-
84875872441
-
Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells
-
Liu, Y., Yao, Z., Zhang, L., Zhu, H., Deng, W., and Qin, C. (2013b). Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells. Neuroscience 238, 371-380. doi: 10.1016/j.neuroscience.2013.01.034
-
(2013)
Neuroscience
, vol.238
, pp. 371-380
-
-
Liu, Y.1
Yao, Z.2
Zhang, L.3
Zhu, H.4
Deng, W.5
Qin, C.6
-
84
-
-
84901357643
-
Rett syndrome and MeCP2
-
Liyanage, V. R. B., and Rastegar, M. (2014). Rett syndrome and MeCP2. Neuromolecular Med. 16, 231-264. doi: 10.1007/s12017-014-8295-9
-
(2014)
Neuromolecular Med
, vol.16
, pp. 231-264
-
-
Liyanage, V.R.B.1
Rastegar, M.2
-
85
-
-
80053168830
-
Ageing: Longevity hits a roadblock
-
Lombard, D. B., Pletcher, S. D., Cantó, C., and Auwerx, J. (2011). Ageing: longevity hits a roadblock. Nature 477, 410-411. doi: 10.1038/477410a
-
(2011)
Nature
, vol.477
, pp. 410-411
-
-
Lombard, D.B.1
Pletcher, S.D.2
Cantó, C.3
Auwerx, J.4
-
86
-
-
84876256827
-
Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues
-
Lu, M., Sarruf, D. A., Li, P., Osborn, O., Sanchez-Alavez, M., Talukdar, S., et al. (2013). Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. J. Biol. Chem. 288, 10722-10735. doi: 10.1074/jbc.M112.443606
-
(2013)
J. Biol. Chem
, vol.288
, pp. 10722-10735
-
-
Lu, M.1
Sarruf, D.A.2
Li, P.3
Osborn, O.4
Sanchez-Alavez, M.5
Talukdar, S.6
-
87
-
-
70349124239
-
Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling
-
Ma, T., Zhao, Y., Kwak, Y. D., Yang, Z., Thompson, R., Luo, Z., et al. (2009). Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. J. Neurosci. 29, 11226-11236. doi: 10.1523/JNEUROSCI.6150-08.2009
-
(2009)
J. Neurosci
, vol.29
, pp. 11226-11236
-
-
Ma, T.1
Zhao, Y.2
Kwak, Y.D.3
Yang, Z.4
Thompson, R.5
Luo, Z.6
-
88
-
-
84905389924
-
Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism
-
Masri, S., Rigor, P., Cervantes, M., Ceglia, N., Sebastian, C., Xiao, C., et al. (2014). Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell 158, 659-672. doi: 10.1016/j.cell.2014.06.050
-
(2014)
Cell
, vol.158
, pp. 659-672
-
-
Masri, S.1
Rigor, P.2
Cervantes, M.3
Ceglia, N.4
Sebastian, C.5
Xiao, C.6
-
89
-
-
84907441244
-
Sirtuins and the circadian clock: Bridging chromatin and metabolism
-
Masri, S., and Sassone-Corsi, P. (2014). Sirtuins and the circadian clock: bridging chromatin and metabolism. Sci. Signal. 7:re6. doi: 10.1126/scisignal.2005685
-
(2014)
Sci. Signal
, vol.7
, pp. 6
-
-
Masri, S.1
Sassone-Corsi, P.2
-
90
-
-
77649138576
-
Circadian rhythms and metabolic syndrome: From experimental genetics to human disease
-
Maury, E., Ramsey, K. M., and Bass, J. (2010). Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ. Res. 106, 447-462. doi: 10.1161/CIRCRESAHA.109.208355
-
(2010)
Circ. Res
, vol.106
, pp. 447-462
-
-
Maury, E.1
Ramsey, K.M.2
Bass, J.3
-
91
-
-
84892500218
-
SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice
-
Mercken, E. M., Hu, J., Krzysik-Walker, S., Wei, M., Li, Y., McBurney, M. W., et al. (2014). SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice. Aging Cell 13, 193-196. doi: 10.1111/acel.12151
-
(2014)
Aging Cell
, vol.13
, pp. 193-196
-
-
Mercken, E.M.1
Hu, J.2
Krzysik-Walker, S.3
Wei, M.4
Li, Y.5
McBurney, M.W.6
-
92
-
-
77954855825
-
SIRT1 is essential for normal cognitive function and synaptic plasticity
-
Michán, S., Li, Y., Chou, M. M. H., Parrella, E., Ge, H., Long, J. M., et al. (2010). SIRT1 is essential for normal cognitive function and synaptic plasticity. J. Neurosci. 30, 9695-9707. doi: 10.1523/JNEUROSCI.0027-10.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 9695-9707
-
-
Michán, S.1
Li, Y.2
Chou, M.M.H.3
Parrella, E.4
Ge, H.5
Long, J.M.6
-
93
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan, S., and Sinclair, D. (2007). Sirtuins in mammals: insights into their biological function. Biochem. J. 404, 1-13. doi: 10.1042/bj20070140
-
(2007)
Biochem. J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
94
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., et al. (2007). Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450, 712-716. doi: 10.1038/nature06261
-
(2007)
Nature
, vol.450
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
-
95
-
-
84895925833
-
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
-
Mitchell, S. J., Martin-Montalvo, A., Mercken, E. M., Palacios, H. H., Ward, T. M., Abulwerdi, G., et al. (2014). The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet. Cell Rep. 6, 836-843. doi: 10.1016/j.celrep.2014.01.031
-
(2014)
Cell Rep
, vol.6
, pp. 836-843
-
-
Mitchell, S.J.1
Martin-Montalvo, A.2
Mercken, E.M.3
Palacios, H.H.4
Ward, T.M.5
Abulwerdi, G.6
-
96
-
-
84875739395
-
Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis
-
Monteserin-Garcia, J., Al-Massadi, O., Seoane, L. M., Alvarez, C. V., Shan, B., Stalla, J., et al. (2013). Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis. FASEB J. 27, 1561-1571. doi: 10.1096/fj.12-220129
-
(2013)
FASEB J
, vol.27
, pp. 1561-1571
-
-
Monteserin-Garcia, J.1
Al-Massadi, O.2
Seoane, L.M.3
Alvarez, C.V.4
Shan, B.5
Stalla, J.6
-
97
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., and Schwartz, M. W. (2006). Central nervous system control of food intake and body weight. Nature 443, 289-295. doi: 10.1038/nature05026
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
98
-
-
84859159081
-
Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease
-
Mudò, G., Mäkelä, J., Di Liberto, V., Tselykh, T. V., Olivieri, M., Piepponen, P., et al. (2012). Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease. Cell. Mol. Life Sci. 69, 1153-1165. doi: 10.1007/s00018-011-0850-z
-
(2012)
Cell. Mol. Life Sci
, vol.69
, pp. 1153-1165
-
-
Mudò, G.1
Mäkelä, J.2
Di Liberto, V.3
Tselykh, T.V.4
Olivieri, M.5
Piepponen, P.6
-
99
-
-
84890547679
-
The contentious history of sirtuin debates
-
Naiman, S., and Cohen, H. Y. (2012). The contentious history of sirtuin debates. Rambam Maimonides Med. J. 3:e0022. doi: 10.5041/RMMJ.10093
-
(2012)
Rambam Maimonides Med. J
, vol.3
-
-
Naiman, S.1
Cohen, H.Y.2
-
100
-
-
47549088250
-
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
-
Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., et al. (2008). The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134, 329-340. doi: 10.1016/j.cell.2008.07.002
-
(2008)
Cell
, vol.134
, pp. 329-340
-
-
Nakahata, Y.1
Kaluzova, M.2
Grimaldi, B.3
Sahar, S.4
Hirayama, J.5
Chen, D.6
-
101
-
-
65549118773
-
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1
-
Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., and Sassone-Corsi, P. (2009). Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science 324, 654-657. doi: 10.1126/science.1170803
-
(2009)
Science
, vol.324
, pp. 654-657
-
-
Nakahata, Y.1
Sahar, S.2
Astarita, G.3
Kaluzova, M.4
Sassone-Corsi, P.5
-
102
-
-
84886838495
-
When is Sirt1 activity bad for dying neurons?
-
Ng, F., and Tang, B. L. (2013). When is Sirt1 activity bad for dying neurons? Front. Cell. Neurosci. 7:186. doi: 10.3389/fncel.2013.00186
-
(2013)
Front. Cell. Neurosci
, vol.7
, pp. 186
-
-
Ng, F.1
Tang, B.L.2
-
103
-
-
84903744004
-
SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
-
North, B. J., Rosenberg, M. A., Jeganathan, K. B., Hafner, A. V., Michan, S., Dai, J., et al. (2014). SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. EMBO J. 33, 1438-1453. doi: 10.15252/embj.201386907
-
(2014)
EMBO J
, vol.33
, pp. 1438-1453
-
-
North, B.J.1
Rosenberg, M.A.2
Jeganathan, K.B.3
Hafner, A.V.4
Michan, S.5
Dai, J.6
-
104
-
-
79956222221
-
Distribution of the longevity gene product, SIRT1, in developing mouse organs
-
Ogawa, T., Wakai, C., Saito, T., Murayama, A., Mimura, Y., Youfu, S., et al. (2011). Distribution of the longevity gene product, SIRT1, in developing mouse organs. Congenit. Anom. (Kyoto) 51, 70-79. doi: 10.1111/j.1741-4520.2010.00304.x
-
(2011)
Congenit. Anom. (Kyoto)
, vol.51
, pp. 70-79
-
-
Ogawa, T.1
Wakai, C.2
Saito, T.3
Murayama, A.4
Mimura, Y.5
Youfu, S.6
-
105
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C elegans
-
Ogg, S., Paradis, S., Gottlieb, S., Patterson, G. I., Lee, L., Tissenbaum, H. A., et al. (1997). The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C elegans. Nature 389, 994-999. doi: 10.1038/40194
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
-
106
-
-
34547599329
-
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
-
Outeiro, T. F., Kontopoulos, E., Altmann, S. M., Kufareva, I., Strathearn, K. E., Amore, A. M., et al. (2007). Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 317, 516-519. doi: 10.1126/science.1143780
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
-
107
-
-
45849121349
-
Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
-
Pallàs, M., Pizarro, J. G., Gutierrez-Cuesta, J., Crespo-Biel, N., Alvira, D., Tajes, M., et al. (2008). Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience 154, 1388-1397. doi: 10.1016/j.neuroscience.2008.04.065
-
(2008)
Neuroscience
, vol.154
, pp. 1388-1397
-
-
Pallàs, M.1
Pizarro, J.G.2
Gutierrez-Cuesta, J.3
Crespo-Biel, N.4
Alvira, D.5
Tajes, M.6
-
108
-
-
84894489242
-
Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction
-
Park, S., Mori, R., and Shimokawa, I. (2013). Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction. Mol. Cells 35, 474-480. doi: 10.1007/s10059-013-0130-x
-
(2013)
Mol. Cells
, vol.35
, pp. 474-480
-
-
Park, S.1
Mori, R.2
Shimokawa, I.3
-
109
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
Parker, J. A., Arango, M., Abderrahmane, S., Lambert, E., Tourette, C., Catoire, H., et al. (2005). Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet. 37, 349-350. doi: 10.1038/ng1534
-
(2005)
Nat. Genet
, vol.37
, pp. 349-350
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
-
110
-
-
15744397372
-
Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK
-
Pedrini, S., Carter, T. L., Prendergast, G., Petanceska, S., Ehrlich, M. E., and Gandy, S. (2005). Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. PLoS Med. 2:e18. doi: 10.1371/journal.pmed.0020018
-
(2005)
PLoS Med
, vol.2
-
-
Pedrini, S.1
Carter, T.L.2
Prendergast, G.3
Petanceska, S.4
Ehrlich, M.E.5
Gandy, S.6
-
111
-
-
42349085704
-
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski, T., Schulze-Topphoff, U., Glumm, R., Baumgart, J., Schröter, F., Ninnemann, O., et al. (2008). Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat. Cell Biol. 10, 385-394. doi: 10.1038/ncb1700
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
Schulze-Topphoff, U.2
Glumm, R.3
Baumgart, J.4
Schröter, F.5
Ninnemann, O.6
-
112
-
-
84864615516
-
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ
-
Qiang, L., Wang, L., Kon, N., Zhao, W., Lee, S., Zhang, Y., et al. (2012). Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell 150, 620-632. doi: 10.1016/j.cell.2012.06.027
-
(2012)
Cell
, vol.150
, pp. 620-632
-
-
Qiang, L.1
Wang, L.2
Kon, N.3
Zhao, W.4
Lee, S.5
Zhang, Y.6
-
113
-
-
33846959101
-
Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
-
Qin, W., Chachich, M., Lane, M., Roth, G., Bryant, M., de Cabo, R., et al. (2006a). Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). J. Alzheimers Dis. 10, 417-422.
-
(2006)
J. Alzheimers Dis
, vol.10
, pp. 417-422
-
-
Qin, W.1
Chachich, M.2
Lane, M.3
Roth, G.4
Bryant, M.5
de Cabo, R.6
-
114
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
Qin, W., Yang, T., Ho, L., Zhao, Z., Wang, J., Chen, L., et al. (2006b). Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J. Biol. Chem. 281, 21745-21754. doi: 10.1074/jbc.m602909200
-
(2006)
J. Biol. Chem
, vol.281
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
-
115
-
-
84856234396
-
Age-associated decrease of SIRT1 expression in rat hippocampus: Prevention by late onset caloric restriction
-
Quintas, A., de Solís, A. J., Díez-Guerra, F. J., Carrascosa, J. M., and Bogónez, E. (2012). Age-associated decrease of SIRT1 expression in rat hippocampus: prevention by late onset caloric restriction. Exp. Gerontol. 47, 198-201. doi: 10.1016/j.exger.2011.11.010
-
(2012)
Exp. Gerontol
, vol.47
, pp. 198-201
-
-
Quintas, A.1
de Solís, A.J.2
Díez-Guerra, F.J.3
Carrascosa, J.M.4
Bogónez, E.5
-
116
-
-
84878584955
-
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain
-
Rafalski, V. A., Ho, P. P., Brett, J. O., Ucar, D., Dugas, J. C., Pollina, E. A., et al. (2013). Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat. Cell Biol. 15, 614-624. doi: 10.1038/ncb2735
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 614-624
-
-
Rafalski, V.A.1
Ho, P.P.2
Brett, J.O.3
Ucar, D.4
Dugas, J.C.5
Pollina, E.A.6
-
117
-
-
80052700953
-
SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance
-
Ramadori, G., Fujikawa, T., Anderson, J., Berglund, E. D., Frazao, R., Michán, S., et al. (2011). SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance. Cell Metab. 14, 301-312. doi: 10.1016/j.cmet.2011.06.014
-
(2011)
Cell Metab
, vol.14
, pp. 301-312
-
-
Ramadori, G.1
Fujikawa, T.2
Anderson, J.3
Berglund, E.D.4
Frazao, R.5
Michán, S.6
-
118
-
-
77956644726
-
SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
-
Ramadori, G., Fujikawa, T., Fukuda, M., Anderson, J., Morgan, D. A., Mostoslavsky, R., et al. (2010). SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 12, 78-87. doi: 10.1016/j.cmet.2010.05.010
-
(2010)
Cell Metab
, vol.12
, pp. 78-87
-
-
Ramadori, G.1
Fujikawa, T.2
Fukuda, M.3
Anderson, J.4
Morgan, D.A.5
Mostoslavsky, R.6
-
119
-
-
54049158932
-
Brain SIRT1: Anatomical distribution and regulation by energy availability
-
Ramadori, G., Lee, C. E., Bookout, A. L., Lee, S., Williams, K. W., Anderson, J., et al. (2008). Brain SIRT1: anatomical distribution and regulation by energy availability. J. Neurosci. 28, 9989-9996. doi: 10.1523/jneurosci.3257-08.2008
-
(2008)
J. Neurosci
, vol.28
, pp. 9989-9996
-
-
Ramadori, G.1
Lee, C.E.2
Bookout, A.L.3
Lee, S.4
Williams, K.W.5
Anderson, J.6
-
120
-
-
65549103855
-
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis
-
Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., et al. (2009). Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science 324, 651-654. doi: 10.1126/science.1171641
-
(2009)
Science
, vol.324
, pp. 651-654
-
-
Ramsey, K.M.1
Yoshino, J.2
Brace, C.S.3
Abrassart, D.4
Kobayashi, Y.5
Marcheva, B.6
-
121
-
-
84889636259
-
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
-
Rardin, M. J., He, W., Nishida, Y., Newman, J. C., Carrico, C., Danielson, S. R., et al. (2013). SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab. 18, 920-933. doi: 10.1016/j.cmet.2013.11.013
-
(2013)
Cell Metab
, vol.18
, pp. 920-933
-
-
Rardin, M.J.1
He, W.2
Nishida, Y.3
Newman, J.C.4
Carrico, C.5
Danielson, S.R.6
-
122
-
-
33747587373
-
Resveratrol mimics ischemic preconditioning in the brain
-
Raval, A. P., Dave, K. R., and Pérez-Pinzón, M. A. (2006). Resveratrol mimics ischemic preconditioning in the brain. J. Cereb. Blood Flow Metab. 26, 1141-1147. doi: 10.1038/sj.jcbfm.9600262
-
(2006)
J. Cereb. Blood Flow Metab
, vol.26
, pp. 1141-1147
-
-
Raval, A.P.1
Dave, K.R.2
Pérez-Pinzón, M.A.3
-
123
-
-
84894180246
-
Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain
-
Revilla, S., Suñol, C., García-Mesa, Y., Giménez-Llort, L., Sanfeliu, C., and Cristòfol, R. (2014). Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain. Neuropharmacology 81, 55-63. doi: 10.1016/j.neuropharm.2014.01.037
-
(2014)
Neuropharmacology
, vol.81
, pp. 55-63
-
-
Revilla, S.1
Suñol, C.2
García-Mesa, Y.3
Giménez-Llort, L.4
Sanfeliu, C.5
Cristòfol, R.6
-
124
-
-
84876791786
-
Connecting cellular metabolism to circadian clocks
-
Rey, G., and Reddy, A. B. (2013). Connecting cellular metabolism to circadian clocks. Trends Cell Biol. 23, 234-241. doi: 10.1016/j.tcb.2013.01.003
-
(2013)
Trends Cell Biol
, vol.23
, pp. 234-241
-
-
Rey, G.1
Reddy, A.B.2
-
125
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M., and Puigserver, P. (2005). Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434, 113-118. doi: 10.1038/nature03354
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
126
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina, B., and Helfand, S. L. (2004). Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. U S A 101, 15998-16003. doi: 10.1073/pnas.0404184101
-
(2004)
Proc. Natl. Acad. Sci. U S A
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
127
-
-
84874815449
-
SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus
-
Saharan, S., Jhaveri, D. J., and Bartlett, P. F. (2013). SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. J. Neurosci. Res. 91, 642-659. doi: 10.1002/jnr.23199
-
(2013)
J. Neurosci. Res
, vol.91
, pp. 642-659
-
-
Saharan, S.1
Jhaveri, D.J.2
Bartlett, P.F.3
-
128
-
-
0346094379
-
Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain
-
Sakamoto, J., Miura, T., Shimamoto, K., and Horio, Y. (2004). Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 556, 281-286. doi: 10.1016/s0014-5793(03)01444-3
-
(2004)
FEBS Lett
, vol.556
, pp. 281-286
-
-
Sakamoto, J.1
Miura, T.2
Shimamoto, K.3
Horio, Y.4
-
129
-
-
84876720051
-
SIRT1 silencing confers neuroprotection through IGF-1 pathway activation
-
Sansone, L., Reali, V., Pellegrini, L., Villanova, L., Aventaggiato, M., Marfe, G., et al. (2013). SIRT1 silencing confers neuroprotection through IGF-1 pathway activation. J. Cell. Physiol. 228, 1754-1761. doi: 10.1002/jcp.24334
-
(2013)
J. Cell. Physiol
, vol.228
, pp. 1754-1761
-
-
Sansone, L.1
Reali, V.2
Pellegrini, L.3
Villanova, L.4
Aventaggiato, M.5
Marfe, G.6
-
130
-
-
84896074276
-
Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice
-
Sasaki, T., Kikuchi, O., Shimpuku, M., Susanti, V. Y., Yokota-Hashimoto, H., Taguchi, R., et al. (2014). Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice. Diabetologia 57, 819-831. doi: 10.1007/s00125-013-3140-5
-
(2014)
Diabetologia
, vol.57
, pp. 819-831
-
-
Sasaki, T.1
Kikuchi, O.2
Shimpuku, M.3
Susanti, V.Y.4
Yokota-Hashimoto, H.5
Taguchi, R.6
-
131
-
-
77954470727
-
Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide
-
Sasaki, T., Kim, H. J., Kobayashi, M., Kitamura, Y. I., Yokota-Hashimoto, H., Shiuchi, T., et al. (2010). Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Endocrinology 151, 2556-2566. doi: 10.1210/en.2009-1319
-
(2010)
Endocrinology
, vol.151
, pp. 2556-2566
-
-
Sasaki, T.1
Kim, H.J.2
Kobayashi, M.3
Kitamura, Y.I.4
Yokota-Hashimoto, H.5
Shiuchi, T.6
-
132
-
-
77955344258
-
SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus
-
Satoh, A., Brace, C. S., Ben-Josef, G., West, T., Wozniak, D. F., Holtzman, D. M., et al. (2010). SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J. Neurosci. 30, 10220-10232. doi: 10.1523/jneurosci.1385-10.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 10220-10232
-
-
Satoh, A.1
Brace, C.S.2
Ben-Josef, G.3
West, T.4
Wozniak, D.F.5
Holtzman, D.M.6
-
133
-
-
84883476818
-
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
-
Satoh, A., Brace, C. S., Rensing, N., Cliften, P., Wozniak, D. F., Herzog, E. D., et al. (2013). Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 18, 416-430. doi: 10.1016/j.cmet.2013.07.013
-
(2013)
Cell Metab
, vol.18
, pp. 416-430
-
-
Satoh, A.1
Brace, C.S.2
Rensing, N.3
Cliften, P.4
Wozniak, D.F.5
Herzog, E.D.6
-
134
-
-
80555142897
-
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
-
Schenk, S., McCurdy, C. E., Philp, A., Chen, M. Z., Holliday, M. J., Bandyopadhyay, G. K., et al. (2011). Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J. Clin. Invest. 121, 4281-4288. doi: 10.1172/JCI58554
-
(2011)
J. Clin. Invest
, vol.121
, pp. 4281-4288
-
-
Schenk, S.1
McCurdy, C.E.2
Philp, A.3
Chen, M.Z.4
Holliday, M.J.5
Bandyopadhyay, G.K.6
-
135
-
-
31144479591
-
A brain-specific microRNA regulates dendritic spine development
-
Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., et al. (2006). A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289. doi: 10.1038/nature04367
-
(2006)
Nature
, vol.439
, pp. 283-289
-
-
Schratt, G.M.1
Tuebing, F.2
Nigh, E.A.3
Kane, C.G.4
Sabatini, M.E.5
Kiebler, M.6
-
136
-
-
84871119123
-
From sirtuin biology to human diseases: An update
-
Sebastián, C., Satterstrom, F. K., Haigis, M. C., and Mostoslavsky, R. (2012). From sirtuin biology to human diseases: an update. J. Biol. Chem. 287, 42444-42452. doi: 10.1074/jbc.r112.402768
-
(2012)
J. Biol. Chem
, vol.287
, pp. 42444-42452
-
-
Sebastián, C.1
Satterstrom, F.K.2
Haigis, M.C.3
Mostoslavsky, R.4
-
137
-
-
62149127767
-
Porcine sirtuin 1 gene clone, expression pattern and regulation by resveratrol
-
Shan, T., Wang, Y., Wu, T., Liu, C., Guo, J., Zhang, Y., et al. (2009). Porcine sirtuin 1 gene clone, expression pattern and regulation by resveratrol. J. Anim. Sci. 87, 895-904. doi: 10.2527/jas.2008-1344
-
(2009)
J. Anim. Sci
, vol.87
, pp. 895-904
-
-
Shan, T.1
Wang, Y.2
Wu, T.3
Liu, C.4
Guo, J.5
Zhang, Y.6
-
138
-
-
0031459980
-
Extrachromosomal rDNA circles-a cause of aging in yeast
-
Sinclair, D. A., and Guarente, L. (1997). Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91, 1033-1042. doi: 10.1016/s0092-8674(00)80493-6
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
139
-
-
84899965665
-
A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease
-
Smith, M. R., Syed, A., Lukacsovich, T., Purcell, J., Barbaro, B. A., Worthge, S. A., et al. (2014). A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. Hum. Mol. Genet. 23, 2995-3007. doi: 10.1093/hmg/ddu010
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. 2995-3007
-
-
Smith, M.R.1
Syed, A.2
Lukacsovich, T.3
Purcell, J.4
Barbaro, B.A.5
Worthge, S.A.6
-
140
-
-
84904181401
-
Resveratrol ameliorates motor neuron degeneration and improves survival in SOD1(G93A) mouse model of amyotrophic lateral sclerosis
-
Song, L., Chen, L., Zhang, X., Li, J., and Le, W. (2014). Resveratrol ameliorates motor neuron degeneration and improves survival in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Biomed. Res. Int. 2014:483501. doi: 10.1155/2014/483501
-
(2014)
Biomed. Res. Int
, vol.2014
, pp. 483501
-
-
Song, L.1
Chen, L.2
Zhang, X.3
Li, J.4
Le, W.5
-
141
-
-
80055085693
-
Role of sirtuins and calorie restriction in neuroprotection: Implications in Alzheimer's and Parkinson's diseases
-
Srivastava, S., and Haigis, M. C. (2011). Role of sirtuins and calorie restriction in neuroprotection: implications in Alzheimer's and Parkinson's diseases. Curr. Pharm. Des. 17, 3418-3433. doi: 10.2174/138161211798072526
-
(2011)
Curr. Pharm. Des
, vol.17
, pp. 3418-3433
-
-
Srivastava, S.1
Haigis, M.C.2
-
142
-
-
75149194039
-
PPAR control: It's SIRTainly as easy as PGC
-
Sugden, M. C., Caton, P. W., and Holness, M. J. (2010). PPAR control: it's SIRTainly as easy as PGC. J. Endocrinol. 204, 93-104. doi: 10.1677/joe-09-0359
-
(2010)
J. Endocrinol
, vol.204
, pp. 93-104
-
-
Sugden, M.C.1
Caton, P.W.2
Holness, M.J.3
-
143
-
-
77953724950
-
Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells
-
Sugino, T., Maruyama, M., Tanno, M., Kuno, A., Houkin, K., and Horio, Y. (2010). Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells. FEBS Lett. 584, 2821-2826. doi: 10.1016/j.neures.2010.07.1100
-
(2010)
FEBS Lett
, vol.584
, pp. 2821-2826
-
-
Sugino, T.1
Maruyama, M.2
Tanno, M.3
Kuno, A.4
Houkin, K.5
Horio, Y.6
-
144
-
-
84939885240
-
The role of cholesterol metabolism in Alzheimer's disease
-
[Epub ahead of print]
-
Sun, J. H., Yu, J. T., and Tan, L. (2014). The role of cholesterol metabolism in Alzheimer's disease. Mol. Neurobiol. doi: 10.1007/s12035-014-8749-y. [Epub ahead of print].
-
(2014)
Mol. Neurobiol
-
-
Sun, J.H.1
Yu, J.T.2
Tan, L.3
-
145
-
-
77049098395
-
Sirt1's complex roles in neuroprotection
-
Tang, B. L. (2009). Sirt1's complex roles in neuroprotection. Cell. Mol. Neurobiol. 29, 1093-1103. doi: 10.1007/s10571-009-9414-2
-
(2009)
Cell. Mol. Neurobiol
, vol.29
, pp. 1093-1103
-
-
Tang, B.L.1
-
146
-
-
79954494901
-
Sirt1's systemic protective roles and its promise as a target in antiaging medicine
-
Tang, B. L. (2011). Sirt1's systemic protective roles and its promise as a target in antiaging medicine. Transl. Res. 157, 276-284. doi: 10.1016/j.trsl.2010.11.006
-
(2011)
Transl. Res
, vol.157
, pp. 276-284
-
-
Tang, B.L.1
-
147
-
-
84887314994
-
Neuroprotective Sirtuin ratio reversed by ApoE4
-
Theendakara, V., Patent, A., Peters Libeu, C. A., Philpot, B., Flores, S., Descamps, O., et al. (2013). Neuroprotective Sirtuin ratio reversed by ApoE4. Proc. Natl. Acad. Sci. U S A 110, 18303-18308. doi: 10.1073/pnas.1314145110
-
(2013)
Proc. Natl. Acad. Sci. U S A
, vol.110
, pp. 18303-18308
-
-
Theendakara, V.1
Patent, A.2
Peters Libeu, C.A.3
Philpot, B.4
Flores, S.5
Descamps, O.6
-
148
-
-
84870565938
-
BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets
-
Tiberi, L., van den Ameele, J., Dimidschstein, J., Piccirilli, J., Gall, D., Herpoel, A., et al. (2012). BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets. Nat. Neurosci. 15, 1627-1635. doi: 10.1038/nn.3264
-
(2012)
Nat. Neurosci
, vol.15
, pp. 1627-1635
-
-
Tiberi, L.1
van den Ameele, J.2
Dimidschstein, J.3
Piccirilli, J.4
Gall, D.5
Herpoel, A.6
-
149
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum, H. A., and Guarente, L. (2001). Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410, 227-230. doi: 10.1038/35065638
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
150
-
-
68149148938
-
Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice
-
Tong, X. K., Nicolakakis, N., Fernandes, P., Ongali, B., Brouillette, J., Quirion, R., et al. (2009). Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice. Neurobiol. Dis. 35, 406-414. doi: 10.1016/j.nbd.2009.06.003
-
(2009)
Neurobiol. Dis
, vol.35
, pp. 406-414
-
-
Tong, X.K.1
Nicolakakis, N.2
Fernandes, P.3
Ongali, B.4
Brouillette, J.5
Quirion, R.6
-
151
-
-
84923923100
-
Minireview: Central Sirt1 regulates energy balance via the melanocortin system and alternate pathways
-
Toorie, A. M., and Nillni, E. A. (2014). Minireview: central Sirt1 regulates energy balance via the melanocortin system and alternate pathways. Mol. Endocrinol. 28, 1423-1434. doi: 10.1210/me.2014-1115
-
(2014)
Mol. Endocrinol
, vol.28
, pp. 1423-1434
-
-
Toorie, A.M.1
Nillni, E.A.2
-
152
-
-
41949097891
-
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
-
van Ham, T. J., Thijssen, K. L., Breitling, R., Hofstra, R. M. W., Plasterk, R. H. A., and Nollen, E. A. A. (2008). C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging. PLoS Genet. 4:e1000027. doi: 10.1371/journal.pgen.1000027
-
(2008)
PLoS Genet
, vol.4
-
-
van Ham, T.J.1
Thijssen, K.L.2
Breitling, R.3
Hofstra, R.M.W.4
Plasterk, R.H.A.5
Nollen, E.A.A.6
-
153
-
-
80053134340
-
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
-
Viswanathan, M., and Guarente, L. (2011). Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes. Nature 477, E1-E2. doi: 10.1038/nature10440
-
(2011)
Nature
, vol.477
, pp. E1-E2
-
-
Viswanathan, M.1
Guarente, L.2
-
154
-
-
79960022038
-
Mitochondrial DNA damage level determines neural stem cell differentiation fate
-
Wang, W., Esbensen, Y., Kunke, D., Suganthan, R., Rachek, L., Bjørås, M., et al. (2011). Mitochondrial DNA damage level determines neural stem cell differentiation fate. J. Neurosci. 31, 9746-9751. doi: 10.1523/jneurosci.0852-11.2011
-
(2011)
J. Neurosci
, vol.31
, pp. 9746-9751
-
-
Wang, W.1
Esbensen, Y.2
Kunke, D.3
Suganthan, R.4
Rachek, L.5
Bjørås, M.6
-
155
-
-
20144386977
-
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
-
Wang, J., Ho, L., Qin, W., Rocher, A. B., Seror, I., Humala, N., et al. (2005). Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J. 19, 659-661. doi: 10.1096/fj.04-3182fje
-
(2005)
FASEB J
, vol.19
, pp. 659-661
-
-
Wang, J.1
Ho, L.2
Qin, W.3
Rocher, A.B.4
Seror, I.5
Humala, N.6
-
156
-
-
84887436276
-
SIRT3: A central regulator of mitochondrial adaptation in health and disease
-
Weir, H. J. M., Lane, J. D., and Balthasar, N. (2013). SIRT3: a central regulator of mitochondrial adaptation in health and disease. Genes Cancer 4, 118-124. doi: 10.1177/1947601913476949
-
(2013)
Genes Cancer
, vol.4
, pp. 118-124
-
-
Weir, H.J.M.1
Lane, J.D.2
Balthasar, N.3
-
157
-
-
0034613164
-
Regulation of C. elegans life-span by insulinlike signaling in the nervous system
-
Wolkow, C. A., Kimura, K. D., Lee, M. S., and Ruvkun, G. (2000). Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290, 147-150. doi: 10.1126/science.290.5489.147
-
(2000)
Science
, vol.290
, pp. 147-150
-
-
Wolkow, C.A.1
Kimura, K.D.2
Lee, M.S.3
Ruvkun, G.4
-
158
-
-
84899490048
-
Cholesterol as a causative factor in Alzheimer's disease: A debatable hypothesis
-
Wood, W. G., Li, L., Müller, W. E., and Eckert, G. P. (2014). Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis. J. Neurochem. 129, 559-572. doi: 10.1111/jnc.12637
-
(2014)
J. Neurochem
, vol.129
, pp. 559-572
-
-
Wood, W.G.1
Li, L.2
Müller, W.E.3
Eckert, G.P.4
-
159
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood, J. G., Rogina, B., Lavu, S., Howitz, K., Helfand, S. L., Tatar, M., et al. (2004). Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430, 686-689. doi: 10.1038/nature02789
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
-
160
-
-
79959726080
-
Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function
-
Wu, D., Qiu, Y., Gao, X., Yuan, X. B., and Zhai, Q. (2011). Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function. PLoS One 6:e21759. doi: 10.1371/journal.pone.0021759
-
(2011)
PLoS One
, vol.6
-
-
Wu, D.1
Qiu, Y.2
Gao, X.3
Yuan, X.B.4
Zhai, Q.5
-
161
-
-
33744494576
-
Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex
-
Wu, A., Ying, Z., and Gomez-Pinilla, F. (2006). Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex. Eur. J. Neurosci. 23, 2573-2580. doi: 10.1111/j.1460-9568.2006.04807.x
-
(2006)
Eur. J. Neurosci
, vol.23
, pp. 2573-2580
-
-
Wu, A.1
Ying, Z.2
Gomez-Pinilla, F.3
-
162
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A., et al. (2004). Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369-2380. doi: 10.1038/sj.emboj.7600244
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
-
163
-
-
77953166978
-
Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems
-
Zakhary, S. M., Ayubcha, D., Dileo, J. N., Jose, R., Leheste, J. R., Horowitz, J. M., et al. (2010). Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems. Anat. Rec. (Hoboken) 293, 1024-1032. doi: 10.1002/ar.21116
-
(2010)
Anat. Rec. (Hoboken)
, vol.293
, pp. 1024-1032
-
-
Zakhary, S.M.1
Ayubcha, D.2
Dileo, J.N.3
Jose, R.4
Leheste, J.R.5
Horowitz, J.M.6
-
164
-
-
78651358721
-
Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells
-
Zhang, Y., Wang, J., Chen, G., Fan, D., and Deng, M. (2011a). Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells. Biochem. Biophys. Res. Commun. 404, 610-614. doi: 10.1016/j.bbrc.2010.12.014
-
(2011)
Biochem. Biophys. Res. Commun
, vol.404
, pp. 610-614
-
-
Zhang, Y.1
Wang, J.2
Chen, G.3
Fan, D.4
Deng, M.5
-
165
-
-
80054123174
-
Protective effects and mechanisms of sirtuins in the nervous system
-
Zhang, F., Wang, S., Gan, L., Vosler, P. S., Gao, Y., Zigmond, M. J., et al. (2011b). Protective effects and mechanisms of sirtuins in the nervous system. Prog. Neurobiol. 95, 373-395. doi: 10.1016/j.pneurobio.2011.09.001
-
(2011)
Prog. Neurobiol
, vol.95
, pp. 373-395
-
-
Zhang, F.1
Wang, S.2
Gan, L.3
Vosler, P.S.4
Gao, Y.5
Zigmond, M.J.6
-
166
-
-
84865318675
-
Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo
-
Zhao, Y., Luo, P., Guo, Q., Li, S., Zhang, L., Zhao, M., et al. (2012). Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo. Exp. Neurol. 237, 489-498. doi: 10.1016/j.expneurol.2012.07.004
-
(2012)
Exp. Neurol
, vol.237
, pp. 489-498
-
-
Zhao, Y.1
Luo, P.2
Guo, Q.3
Li, S.4
Zhang, L.5
Zhao, M.6
-
167
-
-
84863808547
-
SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression
-
Zocchi, L., and Sassone-Corsi, P. (2012). SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression. Epigenetics 7, 695-700. doi: 10.4161/epi.20733
-
(2012)
Epigenetics
, vol.7
, pp. 695-700
-
-
Zocchi, L.1
Sassone-Corsi, P.2
-
168
-
-
84922182239
-
Histone H2A.Z subunit exchange controls consolidation of recent and remote memory
-
Zovkic, I. B., Paulukaitis, B. S., Day, J. J., Etikala, D. M., and Sweatt, J. D. (2014). Histone H2A.Z subunit exchange controls consolidation of recent and remote memory. Nature 515, 582-586. doi: 10.1038/nature13707
-
(2014)
Nature
, vol.515
, pp. 582-586
-
-
Zovkic, I.B.1
Paulukaitis, B.S.2
Day, J.J.3
Etikala, D.M.4
Sweatt, J.D.5
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