-
1
-
-
79960904891
-
Recent progress in understanding the molecular pathogenesis of diabetic nephropathy
-
Abe, H., Recent progress in understanding the molecular pathogenesis of diabetic nephropathy. Rinsho Byori 59 (2011), 179–186.
-
(2011)
Rinsho Byori
, vol.59
, pp. 179-186
-
-
Abe, H.1
-
2
-
-
4143116877
-
Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy
-
Adhikary, L., Chow, F., Nikolic-Paterson, D.J., Stambe, C., Dowling, J., Atkins, R.C., Tesch, G.H., Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy. Diabetologia 47 (2004), 1210–1222.
-
(2004)
Diabetologia
, vol.47
, pp. 1210-1222
-
-
Adhikary, L.1
Chow, F.2
Nikolic-Paterson, D.J.3
Stambe, C.4
Dowling, J.5
Atkins, R.C.6
Tesch, G.H.7
-
3
-
-
0022569728
-
Studies of progressive glomerular sclerosis in the rat
-
Adler, S., Striker, L.J., Striker, G.E., Perkinson, D.T., Hibbert, J., Couser, W.G., Studies of progressive glomerular sclerosis in the rat. Am. J. Pathol. 123 (1986), 553–562.
-
(1986)
Am. J. Pathol.
, vol.123
, pp. 553-562
-
-
Adler, S.1
Striker, L.J.2
Striker, G.E.3
Perkinson, D.T.4
Hibbert, J.5
Couser, W.G.6
-
4
-
-
77955743198
-
Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria
-
Adler, S.G., Schwartz, S., Williams, M.E., Arauz-Pacheco, C., Bolton, W.K., Lee, T., Li, D., Neff, T.B., Urquilla, P.R., Sewell, K.L., Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria. Clin. J. Am. Soc. Nephrol. 5 (2010), 1420–1428.
-
(2010)
Clin. J. Am. Soc. Nephrol.
, vol.5
, pp. 1420-1428
-
-
Adler, S.G.1
Schwartz, S.2
Williams, M.E.3
Arauz-Pacheco, C.4
Bolton, W.K.5
Lee, T.6
Li, D.7
Neff, T.B.8
Urquilla, P.R.9
Sewell, K.L.10
-
5
-
-
77958158176
-
A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy
-
Alkhalaf, A., Klooster, A., van Oeveren, W., Achenbach, U., Kleefstra, N., Slingerland, R.J., Mijnhout, G.S., Bilo, H.J., Gans, R.O., Navis, G.J., Bakker, S.J., A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy. Diabetes Care 33 (2010), 1598–1601.
-
(2010)
Diabetes Care
, vol.33
, pp. 1598-1601
-
-
Alkhalaf, A.1
Klooster, A.2
van Oeveren, W.3
Achenbach, U.4
Kleefstra, N.5
Slingerland, R.J.6
Mijnhout, G.S.7
Bilo, H.J.8
Gans, R.O.9
Navis, G.J.10
Bakker, S.J.11
-
6
-
-
84864360259
-
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
-
Altenhofer, S., Kleikers, P.W., Radermacher, K.A., Scheurer, P., Rob Hermans, J.J., Schiffers, P., Ho, H., Wingler, K., Schmidt, H.H., The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell Mol. Life Sci. 69 (2012), 2327–2343.
-
(2012)
Cell Mol. Life Sci.
, vol.69
, pp. 2327-2343
-
-
Altenhofer, S.1
Kleikers, P.W.2
Radermacher, K.A.3
Scheurer, P.4
Rob Hermans, J.J.5
Schiffers, P.6
Ho, H.7
Wingler, K.8
Schmidt, H.H.9
-
7
-
-
84869238002
-
DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy
-
Alter, M.L., Ott, I.M., von Websky, K., Tsuprykov, O., Sharkovska, Y., Krause-Relle, K., Raila, J., Henze, A., Klein, T., Hocher, B., DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy. Kidney Blood Press. Res. 36 (2012), 119–130.
-
(2012)
Kidney Blood Press. Res.
, vol.36
, pp. 119-130
-
-
Alter, M.L.1
Ott, I.M.2
von Websky, K.3
Tsuprykov, O.4
Sharkovska, Y.5
Krause-Relle, K.6
Raila, J.7
Henze, A.8
Klein, T.9
Hocher, B.10
-
8
-
-
0036236158
-
Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose
-
Amiri, F., Shaw, S., Wang, X., Tang, J., Waller, J.L., Eaton, D.C., Marrero, M.B., Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int. 61 (2002), 1605–1616.
-
(2002)
Kidney Int.
, vol.61
, pp. 1605-1616
-
-
Amiri, F.1
Shaw, S.2
Wang, X.3
Tang, J.4
Waller, J.L.5
Eaton, D.C.6
Marrero, M.B.7
-
9
-
-
33846611038
-
Double-edged action of SOD mimetic in diabetic nephropathy
-
Asaba, K., Tojo, A., Onozato, M.L., Goto, A., Fujita, T., Double-edged action of SOD mimetic in diabetic nephropathy. J. Cardiovasc. Pharm. 49 (2007), 13–19.
-
(2007)
J. Cardiovasc. Pharm.
, vol.49
, pp. 13-19
-
-
Asaba, K.1
Tojo, A.2
Onozato, M.L.3
Goto, A.4
Fujita, T.5
-
10
-
-
0036424140
-
Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes
-
Asanuma, K., Shirato, I., Ishidoh, K., Kominami, E., Tomino, Y., Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes. Kidney Int. 62 (2002), 822–831.
-
(2002)
Kidney Int.
, vol.62
, pp. 822-831
-
-
Asanuma, K.1
Shirato, I.2
Ishidoh, K.3
Kominami, E.4
Tomino, Y.5
-
11
-
-
13444252523
-
Recent advances in the regulation of the TOR pathway by insulin and nutrients
-
Avruch, J., Lin, Y., Long, X., Murthy, S., Ortiz-Vega, S., Recent advances in the regulation of the TOR pathway by insulin and nutrients. Curr. Opin. Clin. Nutr. Metab. Care 8 (2005), 67–72.
-
(2005)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.8
, pp. 67-72
-
-
Avruch, J.1
Lin, Y.2
Long, X.3
Murthy, S.4
Ortiz-Vega, S.5
-
12
-
-
77951157731
-
Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy
-
Barutta, F., Corbelli, A., Mastrocola, R., Gambino, R., Di Marzo, V., Pinach, S., Rastaldi, M.P., Perin, P.C., Gruden, G., Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy. Diabetes 59 (2010), 1046–1054.
-
(2010)
Diabetes
, vol.59
, pp. 1046-1054
-
-
Barutta, F.1
Corbelli, A.2
Mastrocola, R.3
Gambino, R.4
Di Marzo, V.5
Pinach, S.6
Rastaldi, M.P.7
Perin, P.C.8
Gruden, G.9
-
13
-
-
63249092534
-
Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy
-
Berthier, C.C., Zhang, H., Schin, M., Henger, A., Nelson, R.G., Yee, B., Boucherot, A., Neusser, M.A., Cohen, C.D., Carter-Su, C., Argetsinger, L.S., Rastaldi, M.P., Brosius, F.C., Kretzler, M., Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy. Diabetes 58 (2009), 469–477.
-
(2009)
Diabetes
, vol.58
, pp. 469-477
-
-
Berthier, C.C.1
Zhang, H.2
Schin, M.3
Henger, A.4
Nelson, R.G.5
Yee, B.6
Boucherot, A.7
Neusser, M.A.8
Cohen, C.D.9
Carter-Su, C.10
Argetsinger, L.S.11
Rastaldi, M.P.12
Brosius, F.C.13
Kretzler, M.14
-
14
-
-
84866425239
-
Aiding and abetting roles of NOX oxidases in cellular transformation
-
Block, K., Gorin, Y., Aiding and abetting roles of NOX oxidases in cellular transformation. Nat. Rev. Cancer 12 (2012), 627–637.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 627-637
-
-
Block, K.1
Gorin, Y.2
-
15
-
-
77955440687
-
Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy
-
Blouza, S., Dakhli, S., Abid, H., Aissaoui, M., Ardhaoui, I., Ben Abdallah, N., Ben Brahim, S., Ben Ghorbel, I., Ben Salem, N., Beji, S., Chamakhi, S., Derbel, A., Derouiche, F., Djait, F., Doghri, T., Fourti, Y., Gharbi, F., Jellouli, K., Jellazi, N., Kamoun, K., Khedher, A., Letaief, A., Limam, R., Mekaouer, A., Miledi, R., Nagati, K., Naouar, M., Sellem, S., Tarzi, H., Turki, S., Zidi, B., Achour, A., Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy. J. Nephrol. 23 (2010), 415–424.
-
(2010)
J. Nephrol.
, vol.23
, pp. 415-424
-
-
Blouza, S.1
Dakhli, S.2
Abid, H.3
Aissaoui, M.4
Ardhaoui, I.5
Ben Abdallah, N.6
Ben Brahim, S.7
Ben Ghorbel, I.8
Ben Salem, N.9
Beji, S.10
Chamakhi, S.11
Derbel, A.12
Derouiche, F.13
Djait, F.14
Doghri, T.15
Fourti, Y.16
Gharbi, F.17
Jellouli, K.18
Jellazi, N.19
Kamoun, K.20
Khedher, A.21
Letaief, A.22
Limam, R.23
Mekaouer, A.24
Miledi, R.25
Nagati, K.26
Naouar, M.27
Sellem, S.28
Tarzi, H.29
Turki, S.30
Zidi, B.31
Achour, A.32
more..
-
16
-
-
1542269020
-
Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
-
Bogoyevitch, M.A., Boehm, I., Oakley, A., Ketterman, A.J., Barr, R.K., Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential. Biochim. Biophys. Acta 1697 (2004), 89–101.
-
(2004)
Biochim. Biophys. Acta
, vol.1697
, pp. 89-101
-
-
Bogoyevitch, M.A.1
Boehm, I.2
Oakley, A.3
Ketterman, A.J.4
Barr, R.K.5
-
17
-
-
10744223527
-
Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy
-
Bolton, W.K., Cattran, D.C., Williams, M.E., Adler, S.G., Appel, G.B., Cartwright, K., Foiles, P.G., Freedman, B.I., Raskin, P., Ratner, R.E., Spinowitz, B.S., Whittier, F.C., Wuerth, J.P., Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy. Am. J. Nephrol. 24 (2004), 32–40.
-
(2004)
Am. J. Nephrol.
, vol.24
, pp. 32-40
-
-
Bolton, W.K.1
Cattran, D.C.2
Williams, M.E.3
Adler, S.G.4
Appel, G.B.5
Cartwright, K.6
Foiles, P.G.7
Freedman, B.I.8
Raskin, P.9
Ratner, R.E.10
Spinowitz, B.S.11
Whittier, F.C.12
Wuerth, J.P.13
-
18
-
-
84867394203
-
Can we target tubular damage to prevent renal function decline in diabetes?
-
Bonventre, J.V., Can we target tubular damage to prevent renal function decline in diabetes?. Semin. Nephrol. 32 (2012), 452–462.
-
(2012)
Semin. Nephrol.
, vol.32
, pp. 452-462
-
-
Bonventre, J.V.1
-
19
-
-
54949158095
-
Jak/Stat activation in diabetic nephropathy in humans but not mice: transcriptional analysis
-
Boucherot, A.H.A., C.C, Schin, M.L., Burke, K., Bayer, I., HRM, Schmid, Schlondorff, D., Brosius, F., Kretzler, M., Jak/Stat activation in diabetic nephropathy in humans but not mice: transcriptional analysis. J. Am. Soc. Nephrol., 17, 2006, 60A.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 60A
-
-
Boucherot, A.H.A.1
Schin, M.L.2
Burke, K.3
Bayer, I.4
HRM, S.5
Schlondorff, D.6
Brosius, F.7
Kretzler, M.8
-
20
-
-
77952786594
-
Effect of the abrogation of TGF-beta1 by antisense oligonucleotides on the expression of TGF-beta-isoforms and their receptors I and II in isolated fibroblasts from keloid scars
-
Bran, G.M., Goessler, U.R., Schardt, C., Hormann, K., Riedel, F., Sadick, H., Effect of the abrogation of TGF-beta1 by antisense oligonucleotides on the expression of TGF-beta-isoforms and their receptors I and II in isolated fibroblasts from keloid scars. Int. J. Mol. Med 25 (2010), 915–921.
-
(2010)
Int. J. Mol. Med
, vol.25
, pp. 915-921
-
-
Bran, G.M.1
Goessler, U.R.2
Schardt, C.3
Hormann, K.4
Riedel, F.5
Sadick, H.6
-
21
-
-
0028453652
-
Lilly Lecture 1993. Glycation and diabetic complications
-
Brownlee, M., Lilly Lecture 1993. Glycation and diabetic complications. Diabetes 43 (1994), 836–841.
-
(1994)
Diabetes
, vol.43
, pp. 836-841
-
-
Brownlee, M.1
-
22
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee, M., Biochemistry and molecular cell biology of diabetic complications. Nature 414 (2001), 813–820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
23
-
-
0023950461
-
Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
-
Brownlee, M., Cerami, A., Vlassara, H., Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. New Engl. J. Med. 318 (1988), 1315–1321.
-
(1988)
New Engl. J. Med.
, vol.318
, pp. 1315-1321
-
-
Brownlee, M.1
Cerami, A.2
Vlassara, H.3
-
24
-
-
48749126012
-
Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan
-
Cai, W., He, J.C., Zhu, L., Chen, X., Zheng, F., Striker, G.E., Vlassara, H., Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. Am. J. Pathol. 173 (2008), 327–336.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 327-336
-
-
Cai, W.1
He, J.C.2
Zhu, L.3
Chen, X.4
Zheng, F.5
Striker, G.E.6
Vlassara, H.7
-
25
-
-
33748802532
-
Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor
-
Cai, W., He, J.C., Zhu, L., Lu, C., Vlassara, H., Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor. Proc. Natl. Acad. Sci. USA 103 (2006), 13801–13806.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13801-13806
-
-
Cai, W.1
He, J.C.2
Zhu, L.3
Lu, C.4
Vlassara, H.5
-
26
-
-
66849091899
-
Metabolic effects of manidipine
-
Cavalieri, L., Cremonesi, G., Metabolic effects of manidipine. Am. J. Cardiovasc. Drugs : drugs, devices, other interv. 9 (2009), 163–176.
-
(2009)
Am. J. Cardiovasc. Drugs : drugs, devices, other interv.
, vol.9
, pp. 163-176
-
-
Cavalieri, L.1
Cremonesi, G.2
-
27
-
-
4344625264
-
Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen
-
Chander, P.N., Gealekman, O., Brodsky, S.V., Elitok, S., Tojo, A., Crabtree, M., Gross, S.S., Goligorsky, M.S., Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen. J. Am. Soc. Nephrol. 15 (2004), 2391–2403.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 2391-2403
-
-
Chander, P.N.1
Gealekman, O.2
Brodsky, S.V.3
Elitok, S.4
Tojo, A.5
Crabtree, M.6
Gross, S.S.7
Goligorsky, M.S.8
-
28
-
-
33747835223
-
TGF-beta1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing alpha-smooth muscle actin expression
-
Chen, C.A., Hwang, J.C., Guh, J.Y., Tsai, J.C., Chen, H.C., TGF-beta1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing alpha-smooth muscle actin expression. Transl. Res. 148 (2006), 134–141.
-
(2006)
Transl. Res.
, vol.148
, pp. 134-141
-
-
Chen, C.A.1
Hwang, J.C.2
Guh, J.Y.3
Tsai, J.C.4
Chen, H.C.5
-
29
-
-
79551599216
-
The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential
-
Chen, H.Y., Huang, X.R., Wang, W., Li, J.H., Heuchel, R.L., Chung, A.C., Lan, H.Y., The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential. Diabetes 60 (2011), 590–601.
-
(2011)
Diabetes
, vol.60
, pp. 590-601
-
-
Chen, H.Y.1
Huang, X.R.2
Wang, W.3
Li, J.H.4
Heuchel, R.L.5
Chung, A.C.6
Lan, H.Y.7
-
30
-
-
69449094079
-
S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy
-
Chen, J.K., Chen, J., Thomas, G., Kozma, S.C., Harris, R.C., S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy. Am. J. Physiol. Ren. Physiol. 297 (2009), F585–F593.
-
(2009)
Am. J. Physiol. Ren. Physiol.
, vol.297
, pp. F585-F593
-
-
Chen, J.K.1
Chen, J.2
Thomas, G.3
Kozma, S.C.4
Harris, R.C.5
-
31
-
-
33646156170
-
Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1
-
Chen, L.L., Zhang, J.Y., Wang, B.P., Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1. Vasc. Pharm. 44 (2006), 309–315.
-
(2006)
Vasc. Pharm.
, vol.44
, pp. 309-315
-
-
Chen, L.L.1
Zhang, J.Y.2
Wang, B.P.3
-
32
-
-
38749100543
-
Fenofibrate treatment of diabetic rats reduces nitrosative stress, renal cyclooxygenase-2 expression, and enhanced renal prostaglandin release
-
Chen, Y.J., Quilley, J., Fenofibrate treatment of diabetic rats reduces nitrosative stress, renal cyclooxygenase-2 expression, and enhanced renal prostaglandin release. J. Pharm. Exp. Ther. 324 (2008), 658–663.
-
(2008)
J. Pharm. Exp. Ther.
, vol.324
, pp. 658-663
-
-
Chen, Y.J.1
Quilley, J.2
-
33
-
-
84861212961
-
The iron chelators Dp44mT and DFO inhibit TGF-beta-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1)
-
Chen, Z., Zhang, D., Yue, F., Zheng, M., Kovacevic, Z., Richardson, D.R., The iron chelators Dp44mT and DFO inhibit TGF-beta-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). J. Biol. Chem. 287 (2012), 17016–17028.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 17016-17028
-
-
Chen, Z.1
Zhang, D.2
Yue, F.3
Zheng, M.4
Kovacevic, Z.5
Richardson, D.R.6
-
34
-
-
33845890016
-
An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells
-
Cheng, D.W., Jiang, Y., Shalev, A., Kowluru, R., Crook, E.D., Singh, L.P., An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells. Arch. Physiol. Biochem. 112 (2006), 189–218.
-
(2006)
Arch. Physiol. Biochem.
, vol.112
, pp. 189-218
-
-
Cheng, D.W.1
Jiang, Y.2
Shalev, A.3
Kowluru, R.4
Crook, E.D.5
Singh, L.P.6
-
35
-
-
0035897653
-
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5
-
Cheng, G., Cao, Z., Xu, X., van Meir, E.G., Lambeth, J.D., Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. Gene 269 (2001), 131–140.
-
(2001)
Gene
, vol.269
, pp. 131-140
-
-
Cheng, G.1
Cao, Z.2
Xu, X.3
van Meir, E.G.4
Lambeth, J.D.5
-
36
-
-
34948906839
-
Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor
-
Chuang, P.Y., Yu, Q., Fang, W., Uribarri, J., He, J.C., Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor. Kidney Int. 72 (2007), 965–976.
-
(2007)
Kidney Int.
, vol.72
, pp. 965-976
-
-
Chuang, P.Y.1
Yu, Q.2
Fang, W.3
Uribarri, J.4
He, J.C.5
-
37
-
-
35348922424
-
Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes
-
Coughlan, M.T., Forbes, J.M., Cooper, M.E., Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes. Kidney Int.(Suppl.), 2007, S54–S60.
-
(2007)
Kidney Int.
, pp. S54-S60
-
-
Coughlan, M.T.1
Forbes, J.M.2
Cooper, M.E.3
-
38
-
-
84904982625
-
The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
-
Darling, N.J., Cook, S.J., The role of MAPK signalling pathways in the response to endoplasmic reticulum stress. Biochim. Biophys. Acta 1843 (2014), 2150–2163.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 2150-2163
-
-
Darling, N.J.1
Cook, S.J.2
-
39
-
-
35349026241
-
Glomerular and tubular induction of the transcription factor c-Jun in human renal disease
-
de Borst, M.H., Prakash, J., Melenhorst, W.B., van den Heuvel, M.C., Kok, R.J., Navis, G., van Goor, H., Glomerular and tubular induction of the transcription factor c-Jun in human renal disease. J. Pathol. 213 (2007), 219–228.
-
(2007)
J. Pathol.
, vol.213
, pp. 219-228
-
-
de Borst, M.H.1
Prakash, J.2
Melenhorst, W.B.3
van den Heuvel, M.C.4
Kok, R.J.5
Navis, G.6
van Goor, H.7
-
40
-
-
73349139523
-
c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation
-
de Borst, M.H., Prakash, J., Sandovici, M., Klok, P.A., Hamming, I., Kok, R.J., Navis, G., van Goor, H., c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation. J. Pharmacol. Exp. Ther. 331 (2009), 896–905.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.331
, pp. 896-905
-
-
de Borst, M.H.1
Prakash, J.2
Sandovici, M.3
Klok, P.A.4
Hamming, I.5
Kok, R.J.6
Navis, G.7
van Goor, H.8
-
41
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck, R., Zhang, Y.E., Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425 (2003), 577–584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
42
-
-
0033305213
-
Peroxisome proliferator-activated receptors: nuclear control of metabolism
-
Desvergne, B., Wahli, W., Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20 (1999), 649–688.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
43
-
-
0030798335
-
Production and physiological actions of anandamide in the vasculature of the rat kidney
-
Deutsch, D.G., Goligorsky, M.S., Schmid, P.C., Krebsbach, R.J., Schmid, H.H., Das, S.K., Dey, S.K., Arreaza, G., Thorup, C., Stefano, G., Moore, L.C., Production and physiological actions of anandamide in the vasculature of the rat kidney. J. Clin. Invest. 100 (1997), 1538–1546.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1538-1546
-
-
Deutsch, D.G.1
Goligorsky, M.S.2
Schmid, P.C.3
Krebsbach, R.J.4
Schmid, H.H.5
Das, S.K.6
Dey, S.K.7
Arreaza, G.8
Thorup, C.9
Stefano, G.10
Moore, L.C.11
-
44
-
-
79960892180
-
Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes
-
Devaraj, S., Tobias, P., Jialal, I., Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes. Cytokine 55 (2011), 441–445.
-
(2011)
Cytokine
, vol.55
, pp. 441-445
-
-
Devaraj, S.1
Tobias, P.2
Jialal, I.3
-
45
-
-
0015887637
-
Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor
-
Dvornik, E., Simard-Duquesne, N., Krami, M., Sestanj, K., Gabbay, K.H., Kinoshita, J.H., Varma, S.D., Merola, L.O., Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor. Science 182 (1973), 1146–1148.
-
(1973)
Science
, vol.182
, pp. 1146-1148
-
-
Dvornik, E.1
Simard-Duquesne, N.2
Krami, M.3
Sestanj, K.4
Gabbay, K.H.5
Kinoshita, J.H.6
Varma, S.D.7
Merola, L.O.8
-
46
-
-
84856247093
-
Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy
-
Elmarakby, A.A., Sullivan, J.C., Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy. Cardiovasc. Ther. 30 (2012), 49–59.
-
(2012)
Cardiovasc. Ther.
, vol.30
, pp. 49-59
-
-
Elmarakby, A.A.1
Sullivan, J.C.2
-
47
-
-
0036165251
-
Pharmacological inhibitors of MAPK pathways
-
English, J.M., Cobb, M.H., Pharmacological inhibitors of MAPK pathways. Trends Pharmacol. Sci. 23 (2002), 40–45.
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 40-45
-
-
English, J.M.1
Cobb, M.H.2
-
48
-
-
79960563100
-
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
-
Farvid, M.S., Homayouni, F., Amiri, Z., Adelmanesh, F., Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation. Diabetes Res Clin. Pr. 93 (2011), 86–94.
-
(2011)
Diabetes Res Clin. Pr.
, vol.93
, pp. 86-94
-
-
Farvid, M.S.1
Homayouni, F.2
Amiri, Z.3
Adelmanesh, F.4
-
49
-
-
25644452089
-
Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes
-
Farvid, M.S., Jalali, M., Siassi, F., Hosseini, M., Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes. Diabetes Care 28 (2005), 2458–2464.
-
(2005)
Diabetes Care
, vol.28
, pp. 2458-2464
-
-
Farvid, M.S.1
Jalali, M.2
Siassi, F.3
Hosseini, M.4
-
50
-
-
2342545519
-
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
-
Fingar, D.C., Blenis, J., Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23 (2004), 3151–3171.
-
(2004)
Oncogene
, vol.23
, pp. 3151-3171
-
-
Fingar, D.C.1
Blenis, J.2
-
51
-
-
34047251834
-
Histopathology of diabetic nephropathy
-
Fioretto, P., Mauer, M., Histopathology of diabetic nephropathy. Semin. Nephrol. 27 (2007), 195–207.
-
(2007)
Semin. Nephrol.
, vol.27
, pp. 195-207
-
-
Fioretto, P.1
Mauer, M.2
-
52
-
-
34548485289
-
A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis
-
Flanc, R.S., Ma, F.Y., Tesch, G.H., Han, Y., Atkins, R.C., Bennett, B.L., Friedman, G.C., Fan, J.H., Nikolic-Paterson, D.J., A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis. Kidney Int. 72 (2007), 698–708.
-
(2007)
Kidney Int.
, vol.72
, pp. 698-708
-
-
Flanc, R.S.1
Ma, F.Y.2
Tesch, G.H.3
Han, Y.4
Atkins, R.C.5
Bennett, B.L.6
Friedman, G.C.7
Fan, J.H.8
Nikolic-Paterson, D.J.9
-
53
-
-
0347360288
-
ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells
-
Fujita, H., Omori, S., Ishikura, K., Hida, M., Awazu, M., ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells. Am. J. Physiol. Ren. Physiol. 286 (2004), F120–F126.
-
(2004)
Am. J. Physiol. Ren. Physiol.
, vol.286
, pp. F120-F126
-
-
Fujita, H.1
Omori, S.2
Ishikura, K.3
Hida, M.4
Awazu, M.5
-
54
-
-
80053617574
-
N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity
-
Gal, N., Kolusheva, S., Kedei, N., Telek, A., Naeem, T.A., Lewin, N.E., Lim, L., Mannan, P., Garfield, S.H., El Kazzouli, S., Sigano, D.M., Marquez, V.E., Blumberg, P.M., Jelinek, R., N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity. Chembiochem 12 (2011), 2331–2340.
-
(2011)
Chembiochem
, vol.12
, pp. 2331-2340
-
-
Gal, N.1
Kolusheva, S.2
Kedei, N.3
Telek, A.4
Naeem, T.A.5
Lewin, N.E.6
Lim, L.7
Mannan, P.8
Garfield, S.H.9
El Kazzouli, S.10
Sigano, D.M.11
Marquez, V.E.12
Blumberg, P.M.13
Jelinek, R.14
-
55
-
-
67651121856
-
Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells
-
Official publication of the European Dialysis and Transplant Association - European Renal Association.
-
Gava, E., Samad-Zadeh, A., Zimpelmann, J., Bahramifarid, N., Kitten, G.T., Santos, R.A., Touyz, R.M., Burns, K.D., Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells. Nephrol., Dial. Transplant., 24, 2009 1766-1773 Official publication of the European Dialysis and Transplant Association - European Renal Association.
-
(2009)
Nephrol., Dial. Transplant.
, vol.24
, pp. 1766-1773
-
-
Gava, E.1
Samad-Zadeh, A.2
Zimpelmann, J.3
Bahramifarid, N.4
Kitten, G.T.5
Santos, R.A.6
Touyz, R.M.7
Burns, K.D.8
-
57
-
-
79957881425
-
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
-
Godel, M., Hartleben, B., Herbach, N., Liu, S., Zschiedrich, S., Lu, S., Debreczeni-Mor, A., Lindenmeyer, M.T., Rastaldi, M.P., Hartleben, G., Wiech, T., Fornoni, A., Nelson, R.G., Kretzler, M., Wanke, R., Pavenstadt, H., Kerjaschki, D., Cohen, C.D., Hall, M.N., Ruegg, M.A., Inoki, K., Walz, G., Huber, T.B., Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J. Clin. Investig. 121 (2011), 2197–2209.
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 2197-2209
-
-
Godel, M.1
Hartleben, B.2
Herbach, N.3
Liu, S.4
Zschiedrich, S.5
Lu, S.6
Debreczeni-Mor, A.7
Lindenmeyer, M.T.8
Rastaldi, M.P.9
Hartleben, G.10
Wiech, T.11
Fornoni, A.12
Nelson, R.G.13
Kretzler, M.14
Wanke, R.15
Pavenstadt, H.16
Kerjaschki, D.17
Cohen, C.D.18
Hall, M.N.19
Ruegg, M.A.20
Inoki, K.21
Walz, G.22
Huber, T.B.23
more..
-
58
-
-
28044455523
-
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
-
Gorin, Y., Block, K., Hernandez, J., Bhandari, B., Wagner, B., Barnes, J.L., Abboud, H.E., Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J. Biol. Chem. 280 (2005), 39616–39626.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39616-39626
-
-
Gorin, Y.1
Block, K.2
Hernandez, J.3
Bhandari, B.4
Wagner, B.5
Barnes, J.L.6
Abboud, H.E.7
-
59
-
-
0038148216
-
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells
-
Gorin, Y., Ricono, J.M., Kim, N.H., Bhandari, B., Choudhury, G.G., Abboud, H.E., Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells. Am. J. Physiol. Ren. Physiol. 285 (2003), F219–F229.
-
(2003)
Am. J. Physiol. Ren. Physiol.
, vol.285
, pp. F219-F229
-
-
Gorin, Y.1
Ricono, J.M.2
Kim, N.H.3
Bhandari, B.4
Choudhury, G.G.5
Abboud, H.E.6
-
60
-
-
0034951366
-
Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease
-
Guan, Y., Breyer, M.D., Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. Kidney Int. 60 (2001), 14–30.
-
(2001)
Kidney Int.
, vol.60
, pp. 14-30
-
-
Guan, Y.1
Breyer, M.D.2
-
61
-
-
0034748225
-
Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1
-
Guh, J.Y., Huang, J.S., Chen, H.C., Hung, W.C., Lai, Y.H., Chuang, L.Y., Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1. Am. J. Kidney Dis. 38 (2001), 1096–1104.
-
(2001)
Am. J. Kidney Dis.
, vol.38
, pp. 1096-1104
-
-
Guh, J.Y.1
Huang, J.S.2
Chen, H.C.3
Hung, W.C.4
Lai, Y.H.5
Chuang, L.Y.6
-
62
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn, D.M., Shackelford, D.B., Egan, D.F., Mihaylova, M.M., Mery, A., Vasquez, D.S., Turk, B.E., Shaw, R.J., AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol. Cell 30 (2008), 214–226.
-
(2008)
Mol. Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
Turk, B.E.7
Shaw, R.J.8
-
63
-
-
0034817425
-
Activation of protein kinase c-delta and c-epsilon by oxidative stress in early diabetic rat kidney
-
Ha, H., Yu, M.R., Choi, Y.J., Lee, H.B., Activation of protein kinase c-delta and c-epsilon by oxidative stress in early diabetic rat kidney. Am. J. Kidney Dis. 38 (2001), S204–S207.
-
(2001)
Am. J. Kidney Dis.
, vol.38
, pp. S204-S207
-
-
Ha, H.1
Yu, M.R.2
Choi, Y.J.3
Lee, H.B.4
-
64
-
-
0030907294
-
Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions
-
Haneda, M., Araki, S., Togawa, M., Sugimoto, T., Isono, M., Kikkawa, R., Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions. Diabetes 46 (1997), 847–853.
-
(1997)
Diabetes
, vol.46
, pp. 847-853
-
-
Haneda, M.1
Araki, S.2
Togawa, M.3
Sugimoto, T.4
Isono, M.5
Kikkawa, R.6
-
65
-
-
11844304072
-
Restraining PI3K: mTOR signalling goes back to the membrane
-
Harrington, L.S., Findlay, G.M., Lamb, R.F., Restraining PI3K: mTOR signalling goes back to the membrane. Trends Biochem. Sci. 30 (2005), 35–42.
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 35-42
-
-
Harrington, L.S.1
Findlay, G.M.2
Lamb, R.F.3
-
66
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay, N., Sonenberg, N., Upstream and downstream of mTOR. Genes Dev. 18 (2004), 1926–1945.
-
(2004)
Genes Dev.
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
67
-
-
0043074746
-
Role of actions of calcium antagonists on efferent arterioles–with special references to glomerular hypertension
-
Hayashi, K., Ozawa, Y., Fujiwara, K., Wakino, S., Kumagai, H., Saruta, T., Role of actions of calcium antagonists on efferent arterioles–with special references to glomerular hypertension. Am. J. Nephrol. 23 (2003), 229–244.
-
(2003)
Am. J. Nephrol.
, vol.23
, pp. 229-244
-
-
Hayashi, K.1
Ozawa, Y.2
Fujiwara, K.3
Wakino, S.4
Kumagai, H.5
Saruta, T.6
-
68
-
-
3543150126
-
High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal–regulated kinase and protein kinase Cdelta activities in human mesangial cells
-
Hayashida, T., Schnaper, H.W., High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal–regulated kinase and protein kinase Cdelta activities in human mesangial cells. J. Am. Soc. Nephrol. 15 (2004), 2032–2041.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 2032-2041
-
-
Hayashida, T.1
Schnaper, H.W.2
-
69
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz, M.K., Ballif, B.A., Gygi, S.P., Blenis, J., mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123 (2005), 569–580.
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
70
-
-
84865605075
-
Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar rats
-
Hu, Z., Ren, L., Wang, C., Liu, B., Song, G., Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar rats. Kidney Blood Press. Res. 36 (2012), 85–97.
-
(2012)
Kidney Blood Press. Res.
, vol.36
, pp. 85-97
-
-
Hu, Z.1
Ren, L.2
Wang, C.3
Liu, B.4
Song, G.5
-
71
-
-
0033567290
-
Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells
-
Huang, J.S., Guh, J.Y., Hung, W.C., Yang, M.L., Lai, Y.H., Chen, H.C., Chuang, L.Y., Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells. Biochem. J. 342:Pt 1 (1999), 231–238.
-
(1999)
Biochem. J.
, vol.342
, pp. 231-238
-
-
Huang, J.S.1
Guh, J.Y.2
Hung, W.C.3
Yang, M.L.4
Lai, Y.H.5
Chen, H.C.6
Chuang, L.Y.7
-
72
-
-
79951674629
-
mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression
-
Huber, T.B., Walz, G., Kuehn, E.W., mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. Kidney Int. 79 (2011), 502–511.
-
(2011)
Kidney Int.
, vol.79
, pp. 502-511
-
-
Huber, T.B.1
Walz, G.2
Kuehn, E.W.3
-
73
-
-
0032921465
-
Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways
-
Igarashi, M., Wakasaki, H., Takahara, N., Ishii, H., Jiang, Z.Y., Yamauchi, T., Kuboki, K., Meier, M., Rhodes, C.J., King, G.L., Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J. Clin. Investig. 103 (1999), 185–195.
-
(1999)
J. Clin. Investig.
, vol.103
, pp. 185-195
-
-
Igarashi, M.1
Wakasaki, H.2
Takahara, N.3
Ishii, H.4
Jiang, Z.Y.5
Yamauchi, T.6
Kuboki, K.7
Meier, M.8
Rhodes, C.J.9
King, G.L.10
-
74
-
-
0028850573
-
Effects of a calcium channel blocker, manidipine, on insulin sensitivity in essential hypertensives
-
Iimura, O., Shimamoto, K., Masuda, A., Higashiura, K., Miyazaki, Y., Hirata, A., Fukuoka, M., Murakami, H., Effects of a calcium channel blocker, manidipine, on insulin sensitivity in essential hypertensives. J. Diabetes Complicat. 9 (1995), 215–219.
-
(1995)
J. Diabetes Complicat.
, vol.9
, pp. 215-219
-
-
Iimura, O.1
Shimamoto, K.2
Masuda, A.3
Higashiura, K.4
Miyazaki, Y.5
Hirata, A.6
Fukuoka, M.7
Murakami, H.8
-
75
-
-
59149084125
-
Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes
-
Ijaz, A., Tejada, T., Catanuto, P., Xia, X., Elliot, S.J., Lenz, O., Jauregui, A., Saenz, M.O., Molano, R.D., Pileggi, A., Ricordi, C., Fornoni, A., Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes. Kidney Int. 75 (2009), 381–388.
-
(2009)
Kidney Int.
, vol.75
, pp. 381-388
-
-
Ijaz, A.1
Tejada, T.2
Catanuto, P.3
Xia, X.4
Elliot, S.J.5
Lenz, O.6
Jauregui, A.7
Saenz, M.O.8
Molano, R.D.9
Pileggi, A.10
Ricordi, C.11
Fornoni, A.12
-
76
-
-
79957927211
-
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
-
Inoki, K., Mori, H., Wang, J., Suzuki, T., Hong, S., Yoshida, S., Blattner, S.M., Ikenoue, T., Ruegg, M.A., Hall, M.N., Kwiatkowski, D.J., Rastaldi, M.P., Huber, T.B., Kretzler, M., Holzman, L.B., Wiggins, R.C., Guan, K.L., mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Investig. 121 (2011), 2181–2196.
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 2181-2196
-
-
Inoki, K.1
Mori, H.2
Wang, J.3
Suzuki, T.4
Hong, S.5
Yoshida, S.6
Blattner, S.M.7
Ikenoue, T.8
Ruegg, M.A.9
Hall, M.N.10
Kwiatkowski, D.J.11
Rastaldi, M.P.12
Huber, T.B.13
Kretzler, M.14
Holzman, L.B.15
Wiggins, R.C.16
Guan, K.L.17
-
77
-
-
80053378606
-
Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney
-
Irita, J., Okura, T., Jotoku, M., Nagao, T., Enomoto, D., Kurata, M., Desilva, V.R., Miyoshi, K., Matsui, Y., Uede, T., Denhardt, D.T., Rittiling, S.R., Higaki, J., Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. Am. J. Physiol. Ren. Physiol. 301 (2011), F833–F844.
-
(2011)
Am. J. Physiol. Ren. Physiol.
, vol.301
, pp. F833-F844
-
-
Irita, J.1
Okura, T.2
Jotoku, M.3
Nagao, T.4
Enomoto, D.5
Kurata, M.6
Desilva, V.R.7
Miyoshi, K.8
Matsui, Y.9
Uede, T.10
Denhardt, D.T.11
Rittiling, S.R.12
Higaki, J.13
-
78
-
-
73949118948
-
Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
-
Ishibashi, Y., Matsui, T., Takeuchi, M., Yamagishi, S., Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression. Biochem. Biophys. Res. Commun. 391 (2010), 1405–1408.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 1405-1408
-
-
Ishibashi, Y.1
Matsui, T.2
Takeuchi, M.3
Yamagishi, S.4
-
79
-
-
84864287672
-
Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level
-
Ishibashi, Y., Yamagishi, S., Matsui, T., Ohta, K., Tanoue, R., Takeuchi, M., Ueda, S., Nakamura, K., Okuda, S., Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level. Metabolism 61 (2012), 1067–1072.
-
(2012)
Metabolism
, vol.61
, pp. 1067-1072
-
-
Ishibashi, Y.1
Yamagishi, S.2
Matsui, T.3
Ohta, K.4
Tanoue, R.5
Takeuchi, M.6
Ueda, S.7
Nakamura, K.8
Okuda, S.9
-
80
-
-
0033662740
-
Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells
-
Isono, M., Cruz, M.C., Chen, S., Hong, S.W., Ziyadeh, F.N., Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells. J. Am. Soc. Nephrol. 11 (2000), 2222–2230.
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 2222-2230
-
-
Isono, M.1
Cruz, M.C.2
Chen, S.3
Hong, S.W.4
Ziyadeh, F.N.5
-
81
-
-
0031959237
-
Expression of connective tissue growth factor in human renal fibrosis
-
Ito, Y., Aten, J., Bende, R.J., Oemar, B.S., Rabelink, T.J., Weening, J.J., Goldschmeding, R., Expression of connective tissue growth factor in human renal fibrosis. Kidney Int. 53 (1998), 853–861.
-
(1998)
Kidney Int.
, vol.53
, pp. 853-861
-
-
Ito, Y.1
Aten, J.2
Bende, R.J.3
Oemar, B.S.4
Rabelink, T.J.5
Weening, J.J.6
Goldschmeding, R.7
-
82
-
-
53449090135
-
A novel Sartan derivative with very low angiotensin II type 1 receptor affinity protects the kidney in type 2 diabetic rats
-
Izuhara, Y., Sada, T., Yanagisawa, H., Koike, H., Ohtomo, S., Dan, T., Ito, S., Nangaku, M., van Ypersele de Strihou, C., Miyata, T., A novel Sartan derivative with very low angiotensin II type 1 receptor affinity protects the kidney in type 2 diabetic rats. Arterioscler Thromb. Vasc. Biol. 28 (2008), 1767–1773.
-
(2008)
Arterioscler Thromb. Vasc. Biol.
, vol.28
, pp. 1767-1773
-
-
Izuhara, Y.1
Sada, T.2
Yanagisawa, H.3
Koike, H.4
Ohtomo, S.5
Dan, T.6
Ito, S.7
Nangaku, M.8
van Ypersele de Strihou, C.9
Miyata, T.10
-
83
-
-
42249111398
-
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis
-
Izuhara, Y., Takahashi, S., Nangaku, M., Takizawa, S., Ishida, H., Kurokawa, K., van Ypersele de Strihou, C., Hirayama, N., Miyata, T., Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb. Vasc. Biol. 28 (2008), 672–677.
-
(2008)
Arterioscler Thromb. Vasc. Biol.
, vol.28
, pp. 672-677
-
-
Izuhara, Y.1
Takahashi, S.2
Nangaku, M.3
Takizawa, S.4
Ishida, H.5
Kurokawa, K.6
van Ypersele de Strihou, C.7
Hirayama, N.8
Miyata, T.9
-
84
-
-
77952011905
-
A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates
-
Izuhara, Y., Yamaoka, N., Kodama, H., Dan, T., Takizawa, S., Hirayama, N., Meguro, K., van Ypersele de Strihou, C., Miyata, T., A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates. J. Cereb. Blood Flow Metab. 30 (2010), 904–912.
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 904-912
-
-
Izuhara, Y.1
Yamaoka, N.2
Kodama, H.3
Dan, T.4
Takizawa, S.5
Hirayama, N.6
Meguro, K.7
van Ypersele de Strihou, C.8
Miyata, T.9
-
85
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto, E., Facchinetti, V., Liu, D., Soto, N., Wei, S., Jung, S.Y., Huang, Q., Qin, J., Su, B., SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127 (2006), 125–137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
86
-
-
36248947295
-
Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats
-
Janiak, P., Poirier, B., Bidouard, J.P., Cadrouvele, C., Pierre, F., Gouraud, L., Barbosa, I., Dedio, J., Maffrand, J.P., Le Fur, G., O'Connor, S., Herbert, J.M., Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats. Kidney Int. 72 (2007), 1345–1357.
-
(2007)
Kidney Int.
, vol.72
, pp. 1345-1357
-
-
Janiak, P.1
Poirier, B.2
Bidouard, J.P.3
Cadrouvele, C.4
Pierre, F.5
Gouraud, L.6
Barbosa, I.7
Dedio, J.8
Maffrand, J.P.9
Le Fur, G.10
O'Connor, S.11
Herbert, J.M.12
-
87
-
-
84865389448
-
Challenging delivery of VLHL NS plasminogen activator inhibitor-1 by osmotic pumps in diabetic mouse: a case report
-
Jankun, J., Challenging delivery of VLHL NS plasminogen activator inhibitor-1 by osmotic pumps in diabetic mouse: a case report. Exp. Ther. Med. 4 (2012), 661–664.
-
(2012)
Exp. Ther. Med.
, vol.4
, pp. 661-664
-
-
Jankun, J.1
-
88
-
-
84863490758
-
Protein kinase C inhibitor prevents renal apoptotic and fibrotic changes in response to partial ureteric obstruction
-
Juan, Y.S., Chuang, S.M., Long, C.Y., Lin, R.J., Liu, K.M., Wu, W.J., Huang, C.H., Protein kinase C inhibitor prevents renal apoptotic and fibrotic changes in response to partial ureteric obstruction. BJU Int. 110 (2012), 283–292.
-
(2012)
BJU Int.
, vol.110
, pp. 283-292
-
-
Juan, Y.S.1
Chuang, S.M.2
Long, C.Y.3
Lin, R.J.4
Liu, K.M.5
Wu, W.J.6
Huang, C.H.7
-
89
-
-
77953808713
-
Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells
-
Jung, D.H., Kim, Y.S., Kim, N.H., Lee, J., Jang, D.S., Kim, J.S., Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells. Eur. J. Pharm. 641 (2010), 7–14.
-
(2010)
Eur. J. Pharm.
, vol.641
, pp. 7-14
-
-
Jung, D.H.1
Kim, Y.S.2
Kim, N.H.3
Lee, J.4
Jang, D.S.5
Kim, J.S.6
-
90
-
-
52449109519
-
FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells
-
Jung, D.S., Li, J.J., Kwak, S.J., Lee, S.H., Park, J., Song, Y.S., Yoo, T.H., Han, S.H., Lee, J.E., Kim, D.K., Moon, S.J., Kim, Y.S., Han, D.S., Kang, S.W., FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells. Am. J. Physiol. Ren. Physiol. 295 (2008), F595–F604.
-
(2008)
Am. J. Physiol. Ren. Physiol.
, vol.295
, pp. F595-F604
-
-
Jung, D.S.1
Li, J.J.2
Kwak, S.J.3
Lee, S.H.4
Park, J.5
Song, Y.S.6
Yoo, T.H.7
Han, S.H.8
Lee, J.E.9
Kim, D.K.10
Moon, S.J.11
Kim, Y.S.12
Han, D.S.13
Kang, S.W.14
-
91
-
-
33845978803
-
TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells
-
Jung, K.Y., Chen, K., Kretzler, M., Wu, C., TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells. J. Am. Soc. Nephrol. 18 (2007), 66–73.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 66-73
-
-
Jung, K.Y.1
Chen, K.2
Kretzler, M.3
Wu, C.4
-
92
-
-
79960036957
-
H+/myo-inositol transporter genes, hmit-1.1 and hmit-1.2, have roles in the osmoprotective response in Caenorhabditis elegans
-
Kage-Nakadai, E., Uehara, T., Mitani, S., H+/myo-inositol transporter genes, hmit-1.1 and hmit-1.2, have roles in the osmoprotective response in Caenorhabditis elegans. Biochem. Biophys. Res Commun. 410 (2011), 471–477.
-
(2011)
Biochem. Biophys. Res Commun.
, vol.410
, pp. 471-477
-
-
Kage-Nakadai, E.1
Uehara, T.2
Mitani, S.3
-
93
-
-
77955172248
-
Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria
-
Kang, Y.S., Li, Y., Dai, C., Kiss, L.P., Wu, C., Liu, Y., Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int. 78 (2010), 363–373.
-
(2010)
Kidney Int.
, vol.78
, pp. 363-373
-
-
Kang, Y.S.1
Li, Y.2
Dai, C.3
Kiss, L.P.4
Wu, C.5
Liu, Y.6
-
94
-
-
70449650467
-
Anti-glycation and anti-albuminuric effects of GLY-230 in human diabetes
-
Kennedy, L., Solano, M.P., Meneghini, L., Lo, M., Cohen, M.P., Anti-glycation and anti-albuminuric effects of GLY-230 in human diabetes. Am. J. Nephrol. 31 (2010), 110–116.
-
(2010)
Am. J. Nephrol.
, vol.31
, pp. 110-116
-
-
Kennedy, L.1
Solano, M.P.2
Meneghini, L.3
Lo, M.4
Cohen, M.P.5
-
95
-
-
84861986448
-
Challenges ahead in signal transduction: MAPK as an example
-
Kiel, C., Serrano, L., Challenges ahead in signal transduction: MAPK as an example. Curr. Opin. Biotechnol. 23 (2012), 305–314.
-
(2012)
Curr. Opin. Biotechnol.
, vol.23
, pp. 305-314
-
-
Kiel, C.1
Serrano, L.2
-
96
-
-
0142187240
-
Activation of the TGF-beta/Smad signaling pathway in focal segmental glomerulosclerosis
-
Kim, J.H., Kim, B.K., Moon, K.C., Hong, H.K., Lee, H.S., Activation of the TGF-beta/Smad signaling pathway in focal segmental glomerulosclerosis. Kidney Int. 64 (2003), 1715–1721.
-
(2003)
Kidney Int.
, vol.64
, pp. 1715-1721
-
-
Kim, J.H.1
Kim, B.K.2
Moon, K.C.3
Hong, H.K.4
Lee, H.S.5
-
97
-
-
3142579185
-
p38 MAPK mediates the expression of type I collagen induced by TGF-beta 2 in human retinal pigment epithelial cells ARPE-19
-
Kimoto, K., Nakatsuka, K., Matsuo, N., Yoshioka, H., p38 MAPK mediates the expression of type I collagen induced by TGF-beta 2 in human retinal pigment epithelial cells ARPE-19. Invest. Ophthalmol. Vis. Sci. 45 (2004), 2431–2437.
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 2431-2437
-
-
Kimoto, K.1
Nakatsuka, K.2
Matsuo, N.3
Yoshioka, H.4
-
98
-
-
80054692657
-
Parathyroid hormone (PTH) regulates the sodium chloride cotransporter via Ras guanyl releasing protein 1 (Ras-GRP1) and extracellular signal-regulated kinase (ERK)1/2 mitogen-activated protein kinase (MAPK) pathway
-
Ko, B., Cooke, L.L., Hoover, R.S., Parathyroid hormone (PTH) regulates the sodium chloride cotransporter via Ras guanyl releasing protein 1 (Ras-GRP1) and extracellular signal-regulated kinase (ERK)1/2 mitogen-activated protein kinase (MAPK) pathway. Transl. Res. 158 (2011), 282–289.
-
(2011)
Transl. Res.
, vol.158
, pp. 282-289
-
-
Ko, B.1
Cooke, L.L.2
Hoover, R.S.3
-
99
-
-
56949105387
-
Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
-
Ko, G.J., Kang, Y.S., Han, S.Y., Lee, M.H., Song, H.K., Han, K.H., Kim, H.K., Han, J.Y., Cha, D.R., Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrol. Dial. Transplant. 23 (2008), 2750–2760.
-
(2008)
Nephrol. Dial. Transplant.
, vol.23
, pp. 2750-2760
-
-
Ko, G.J.1
Kang, Y.S.2
Han, S.Y.3
Lee, M.H.4
Song, H.K.5
Han, K.H.6
Kim, H.K.7
Han, J.Y.8
Cha, D.R.9
-
100
-
-
37549027570
-
Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species
-
Koli, K., Myllarniemi, M., Keski-Oja, J., Kinnula, V.L., Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species. Antioxid. Redox Signal. 10 (2008), 333–342.
-
(2008)
Antioxid. Redox Signal.
, vol.10
, pp. 333-342
-
-
Koli, K.1
Myllarniemi, M.2
Keski-Oja, J.3
Kinnula, V.L.4
-
101
-
-
0035865279
-
Latency, activation, and binding proteins of TGF-beta
-
Koli, K., Saharinen, J., Hyytiainen, M., Penttinen, C., Keski-Oja, J., Latency, activation, and binding proteins of TGF-beta. Microsc. Res. Tech. 52 (2001), 354–362.
-
(2001)
Microsc. Res. Tech.
, vol.52
, pp. 354-362
-
-
Koli, K.1
Saharinen, J.2
Hyytiainen, M.3
Penttinen, C.4
Keski-Oja, J.5
-
102
-
-
0031975643
-
High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells
-
Kolm-Litty, V., Sauer, U., Nerlich, A., Lehmann, R., Schleicher, E.D., High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. J. Clin. Invest. 101 (1998), 160–169.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 160-169
-
-
Kolm-Litty, V.1
Sauer, U.2
Nerlich, A.3
Lehmann, R.4
Schleicher, E.D.5
-
103
-
-
84865636694
-
Hesperetin ameliorates hyperglycemia induced retinal vasculopathy via anti-angiogenic effects in experimental diabetic rats
-
Kumar, B., Gupta, S.K., Srinivasan, B.P., Nag, T.C., Srivastava, S., Saxena, R., Hesperetin ameliorates hyperglycemia induced retinal vasculopathy via anti-angiogenic effects in experimental diabetic rats. Vasc. Pharm. 57 (2012), 201–207.
-
(2012)
Vasc. Pharm.
, vol.57
, pp. 201-207
-
-
Kumar, B.1
Gupta, S.K.2
Srinivasan, B.P.3
Nag, T.C.4
Srivastava, S.5
Saxena, R.6
-
104
-
-
84935002203
-
Extracellular superoxide dismutase ameliorates streptozotocin-induced rat diabetic nephropathy via inhibiting the ROS/ERK1/2 signaling
-
Kuo, C.W., Shen, C.J., Tung, Y.T., Chen, H.L., Chen, Y.H., Chang, W.H., Cheng, K.C., Yang, S.H., Chen, C.M., Extracellular superoxide dismutase ameliorates streptozotocin-induced rat diabetic nephropathy via inhibiting the ROS/ERK1/2 signaling. Life Sci. 135 (2015), 77–86.
-
(2015)
Life Sci.
, vol.135
, pp. 77-86
-
-
Kuo, C.W.1
Shen, C.J.2
Tung, Y.T.3
Chen, H.L.4
Chen, Y.H.5
Chang, W.H.6
Cheng, K.C.7
Yang, S.H.8
Chen, C.M.9
-
105
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis, J.M., Avruch, J., Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81 (2001), 807–869.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
106
-
-
80755172244
-
Modulation of AT-1R/MAPK cascade by an olmesartan treatment attenuates diabetic nephropathy in streptozotocin-induced diabetic mice
-
Lakshmanan, A.P., Thandavarayan, R.A., Watanabe, K., Sari, F.R., Meilei, H., Giridharan, V.V., Sukumaran, V., Soetikno, V., Arumugam, S., Suzuki, K., Kodama, M., Modulation of AT-1R/MAPK cascade by an olmesartan treatment attenuates diabetic nephropathy in streptozotocin-induced diabetic mice. Mol. Cell. Endocrinol. 348 (2012), 104–111.
-
(2012)
Mol. Cell. Endocrinol.
, vol.348
, pp. 104-111
-
-
Lakshmanan, A.P.1
Thandavarayan, R.A.2
Watanabe, K.3
Sari, F.R.4
Meilei, H.5
Giridharan, V.V.6
Sukumaran, V.7
Soetikno, V.8
Arumugam, S.9
Suzuki, K.10
Kodama, M.11
-
107
-
-
79952654623
-
Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-gamma agonist action
-
Lakshmanan, A.P., Watanabe, K., Thandavarayan, R.A., Sari, F.R., Harima, M., Giridharan, V.V., Soetikno, V., Kodama, M., Aizawa, Y., Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-gamma agonist action. Free Radic. Res. 45 (2011), 575–584.
-
(2011)
Free Radic. Res.
, vol.45
, pp. 575-584
-
-
Lakshmanan, A.P.1
Watanabe, K.2
Thandavarayan, R.A.3
Sari, F.R.4
Harima, M.5
Giridharan, V.V.6
Soetikno, V.7
Kodama, M.8
Aizawa, Y.9
-
108
-
-
84859442422
-
Mechanisms and consequences of TGF-ss overexpression by podocytes in progressive podocyte disease
-
Lee, H.S., Mechanisms and consequences of TGF-ss overexpression by podocytes in progressive podocyte disease. Cell Tissue Res. 347 (2012), 129–140.
-
(2012)
Cell Tissue Res.
, vol.347
, pp. 129-140
-
-
Lee, H.S.1
-
109
-
-
77950208651
-
Effects of TGF-beta on podocyte growth and disease progression in proliferative podocytopathies
-
Lee, H.S., Song, C.Y., Effects of TGF-beta on podocyte growth and disease progression in proliferative podocytopathies. Kidney Blood Press. Res 33 (2010), 24–29.
-
(2010)
Kidney Blood Press. Res
, vol.33
, pp. 24-29
-
-
Lee, H.S.1
Song, C.Y.2
-
110
-
-
70350336006
-
Urocortin 1 improves renal function in rats with streptozotocin-induced diabetes by inhibiting overproduction of TGF-beta 1 and VEGF
-
Li, X., Hu, J., Zhang, Q., Sun, X., Li, S., Urocortin 1 improves renal function in rats with streptozotocin-induced diabetes by inhibiting overproduction of TGF-beta 1 and VEGF. Br. J. Pharmacol. 157 (2009), 994–1003.
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 994-1003
-
-
Li, X.1
Hu, J.2
Zhang, Q.3
Sun, X.4
Li, S.5
-
111
-
-
39549098861
-
Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
-
Li, Y., Kang, Y.S., Dai, C., Kiss, L.P., Wen, X., Liu, Y., Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am. J. Pathol. 172 (2008), 299–308.
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 299-308
-
-
Li, Y.1
Kang, Y.S.2
Dai, C.3
Kiss, L.P.4
Wen, X.5
Liu, Y.6
-
112
-
-
80052102425
-
Evaluation of JNK blockade as an early intervention treatment for type 1 diabetic nephropathy in hypertensive rats
-
Lim, A.K., Ma, F.Y., Nikolic-Paterson, D.J., Ozols, E., Young, M.J., Bennett, B.L., Friedman, G.C., Tesch, G.H., Evaluation of JNK blockade as an early intervention treatment for type 1 diabetic nephropathy in hypertensive rats. Am. J. Nephrol. 34 (2011), 337–346.
-
(2011)
Am. J. Nephrol.
, vol.34
, pp. 337-346
-
-
Lim, A.K.1
Ma, F.Y.2
Nikolic-Paterson, D.J.3
Ozols, E.4
Young, M.J.5
Bennett, B.L.6
Friedman, G.C.7
Tesch, G.H.8
-
113
-
-
58149462797
-
Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice
-
Lim, A.K., Nikolic-Paterson, D.J., Ma, F.Y., Ozols, E., Thomas, M.C., Flavell, R.A., Davis, R.J., Tesch, G.H., Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice. Diabetologia 52 (2009), 347–358.
-
(2009)
Diabetologia
, vol.52
, pp. 347-358
-
-
Lim, A.K.1
Nikolic-Paterson, D.J.2
Ma, F.Y.3
Ozols, E.4
Thomas, M.C.5
Flavell, R.A.6
Davis, R.J.7
Tesch, G.H.8
-
114
-
-
84862922902
-
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy
-
Lin, M., Yiu, W.H., Wu, H.J., Chan, L.Y., Leung, J.C., Au, W.S., Chan, K.W., Lai, K.N., Tang, S.C., Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. J. Am. Soc. Nephrol. 23 (2012), 86–102.
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 86-102
-
-
Lin, M.1
Yiu, W.H.2
Wu, H.J.3
Chan, L.Y.4
Leung, J.C.5
Au, W.S.6
Chan, K.W.7
Lai, K.N.8
Tang, S.C.9
-
116
-
-
84868617786
-
The in vitro protective effects of curcumin and demethoxycurcumin in Curcuma longa extract on advanced glycation end products-induced mesangial cell apoptosis and oxidative stress
-
Liu, J.P., Feng, L., Zhu, M.M., Wang, R.S., Zhang, M.H., Hu, S.Y., Jia, X.B., Wu, J.J., The in vitro protective effects of curcumin and demethoxycurcumin in Curcuma longa extract on advanced glycation end products-induced mesangial cell apoptosis and oxidative stress. Planta Med. 78 (2012), 1757–1760.
-
(2012)
Planta Med.
, vol.78
, pp. 1757-1760
-
-
Liu, J.P.1
Feng, L.2
Zhu, M.M.3
Wang, R.S.4
Zhang, M.H.5
Hu, S.Y.6
Jia, X.B.7
Wu, J.J.8
-
117
-
-
84890120886
-
Up-regulation of glyoxalase 1 by mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats
-
Liu, Y.W., Zhu, X., Zhang, L., Lu, Q., Wang, J.Y., Zhang, F., Guo, H., Yin, J.L., Yin, X.X., Up-regulation of glyoxalase 1 by mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats. Eur. J. Pharm. 721 (2013), 355–364.
-
(2013)
Eur. J. Pharm.
, vol.721
, pp. 355-364
-
-
Liu, Y.W.1
Zhu, X.2
Zhang, L.3
Lu, Q.4
Wang, J.Y.5
Zhang, F.6
Guo, H.7
Yin, J.L.8
Yin, X.X.9
-
118
-
-
33646352217
-
Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats
-
Lloberas, N., Cruzado, J.M., Franquesa, M., Herrero-Fresneda, I., Torras, J., Alperovich, G., Rama, I., Vidal, A., Grinyo, J.M., Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats. J. Am. Soc. Nephrol. 17 (2006), 1395–1404.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1395-1404
-
-
Lloberas, N.1
Cruzado, J.M.2
Franquesa, M.3
Herrero-Fresneda, I.4
Torras, J.5
Alperovich, G.6
Rama, I.7
Vidal, A.8
Grinyo, J.M.9
-
119
-
-
67449161568
-
Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy
-
Lu, T.C., Wang, Z.H., Feng, X., Chuang, P.Y., Fang, W., Shen, Y., Levy, D.E., Xiong, H., Chen, N., He, J.C., Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy. Kidney Int. 76 (2009), 63–71.
-
(2009)
Kidney Int.
, vol.76
, pp. 63-71
-
-
Lu, T.C.1
Wang, Z.H.2
Feng, X.3
Chuang, P.Y.4
Fang, W.5
Shen, Y.6
Levy, D.E.7
Xiong, H.8
Chen, N.9
He, J.C.10
-
120
-
-
33846689276
-
A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis
-
Ma, F.Y., Flanc, R.S., Tesch, G.H., Han, Y., Atkins, R.C., Bennett, B.L., Friedman, G.C., Fan, J.H., Nikolic-Paterson, D.J., A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis. J. Am. Soc. Nephrol. 18 (2007), 472–484.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 472-484
-
-
Ma, F.Y.1
Flanc, R.S.2
Tesch, G.H.3
Han, Y.4
Atkins, R.C.5
Bennett, B.L.6
Friedman, G.C.7
Fan, J.H.8
Nikolic-Paterson, D.J.9
-
121
-
-
62749091607
-
The role of stress-activated protein kinase signaling in renal pathophysiology
-
Ma, F.Y., Liu, J., Nikolic-Paterson, D.J., The role of stress-activated protein kinase signaling in renal pathophysiology. Braz. J. Med. Biol. Res. 42 (2009), 29–37.
-
(2009)
Braz. J. Med. Biol. Res.
, vol.42
, pp. 29-37
-
-
Ma, F.Y.1
Liu, J.2
Nikolic-Paterson, D.J.3
-
122
-
-
84964662010
-
Beneficial role of vitamin K supplementation on insulin sensitivity, glucose metabolism, and the reduced risk of type 2 diabetes: a review
-
(Burbank, Los Angeles County, Calif.)
-
Manna, P., Kalita, J., Beneficial role of vitamin K supplementation on insulin sensitivity, glucose metabolism, and the reduced risk of type 2 diabetes: a review. Nutrition, 32, 2016 732-739 (Burbank, Los Angeles County, Calif.).
-
(2016)
Nutrition
, vol.32
, pp. 732-739
-
-
Manna, P.1
Kalita, J.2
-
123
-
-
23344436895
-
Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells
-
Mariappan, M.M., Senthil, D., Natarajan, K.S., Choudhury, G.G., Kasinath, B.S., Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells. J. Biol. Chem. 280 (2005), 28402–28411.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28402-28411
-
-
Mariappan, M.M.1
Senthil, D.2
Natarajan, K.S.3
Choudhury, G.G.4
Kasinath, B.S.5
-
124
-
-
0029742775
-
Hexosamines and insulin resistance
-
McClain, D.A., Crook, E.D., Hexosamines and insulin resistance. Diabetes 45 (1996), 1003–1009.
-
(1996)
Diabetes
, vol.45
, pp. 1003-1009
-
-
McClain, D.A.1
Crook, E.D.2
-
125
-
-
4644327657
-
Manidipine: a review of its use in the management of hypertension
-
McKeage, K., Scott, L.J., Manidipine: a review of its use in the management of hypertension. Drugs 64 (2004), 1923–1940.
-
(2004)
Drugs
, vol.64
, pp. 1923-1940
-
-
McKeage, K.1
Scott, L.J.2
-
126
-
-
77953461268
-
p38 MAPK inhibition reduces diabetes-induced impairment of wound healing
-
Medicherla, S., Wadsworth, S., Cullen, B., Silcock, D., Ma, J.Y., Mangadu, R., Kerr, I., Chakravarty, S., Luedtke, G.L., Dugar, S., Protter, A.A., Higgins, L.S., p38 MAPK inhibition reduces diabetes-induced impairment of wound healing. Diabetes, Metab. Syndr. Obes. : Targets Ther. 2 (2009), 91–100.
-
(2009)
Diabetes, Metab. Syndr. Obes. : Targets Ther.
, vol.2
, pp. 91-100
-
-
Medicherla, S.1
Wadsworth, S.2
Cullen, B.3
Silcock, D.4
Ma, J.Y.5
Mangadu, R.6
Kerr, I.7
Chakravarty, S.8
Luedtke, G.L.9
Dugar, S.10
Protter, A.A.11
Higgins, L.S.12
-
127
-
-
16244408061
-
The role of LOX-1, a novel lectin-like receptor for oxidized low density lipoprotein, in atherosclerosis
-
Mehta, J.L., The role of LOX-1, a novel lectin-like receptor for oxidized low density lipoprotein, in atherosclerosis. Can. J. Cardiol. 20:Suppl B (2004), 32B–36B.
-
(2004)
Can. J. Cardiol.
, vol.20
, pp. 32B-36B
-
-
Mehta, J.L.1
-
128
-
-
34047235730
-
Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo
-
Meier, M., Menne, J., Park, J.K., Holtz, M., Gueler, F., Kirsch, T., Schiffer, M., Mengel, M., Lindschau, C., Leitges, M., Haller, H., Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo. J. Am. Soc. Nephrol. 18 (2007), 1190–1198.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 1190-1198
-
-
Meier, M.1
Menne, J.2
Park, J.K.3
Holtz, M.4
Gueler, F.5
Kirsch, T.6
Schiffer, M.7
Mengel, M.8
Lindschau, C.9
Leitges, M.10
Haller, H.11
-
129
-
-
3242749031
-
Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice
-
Menne, J., Park, J.K., Boehne, M., Elger, M., Lindschau, C., Kirsch, T., Meier, M., Gueler, F., Fiebeler, A., Bahlmann, F.H., Leitges, M., Haller, H., Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice. Diabetes 53 (2004), 2101–2109.
-
(2004)
Diabetes
, vol.53
, pp. 2101-2109
-
-
Menne, J.1
Park, J.K.2
Boehne, M.3
Elger, M.4
Lindschau, C.5
Kirsch, T.6
Meier, M.7
Gueler, F.8
Fiebeler, A.9
Bahlmann, F.H.10
Leitges, M.11
Haller, H.12
-
130
-
-
77955888805
-
Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g] indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy
-
Meyers, M.J., Arhancet, G.B., Hockerman, S.L., Chen, X., Long, S.A., Mahoney, M.W., Rico, J.R., Garland, D.J., Blinn, J.R., Collins, J.T., Yang, S., Huang, H.C., McGee, K.F., Wendling, J.M., Dietz, J.D., Payne, M.A., Homer, B.L., Heron, M.I., Reitz, D.B., Hu, X., Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g] indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy. J. Med. Chem. 53 (2010), 5979–6002.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 5979-6002
-
-
Meyers, M.J.1
Arhancet, G.B.2
Hockerman, S.L.3
Chen, X.4
Long, S.A.5
Mahoney, M.W.6
Rico, J.R.7
Garland, D.J.8
Blinn, J.R.9
Collins, J.T.10
Yang, S.11
Huang, H.C.12
McGee, K.F.13
Wendling, J.M.14
Dietz, J.D.15
Payne, M.A.16
Homer, B.L.17
Heron, M.I.18
Reitz, D.B.19
Hu, X.20
more..
-
131
-
-
84880765831
-
β-Glucan administration to diabetic rats alleviates oxidative stress by lowering hyperglycaemia, decreasing non-enzymatic glycation and protein O-GlcNAcylation
-
Mihailović, M., Arambašić, J., Uskoković, A., Dinić, S., Grdović, N., Marković, J., Bauder, J., Poznanović, G., Vidaković, M., β-Glucan administration to diabetic rats alleviates oxidative stress by lowering hyperglycaemia, decreasing non-enzymatic glycation and protein O-GlcNAcylation. J. Funct. Foods 5 (2013), 1226–1234.
-
(2013)
J. Funct. Foods
, vol.5
, pp. 1226-1234
-
-
Mihailović, M.1
Arambašić, J.2
Uskoković, A.3
Dinić, S.4
Grdović, N.5
Marković, J.6
Bauder, J.7
Poznanović, G.8
Vidaković, M.9
-
132
-
-
77950226497
-
Ameliorative effect of the cinnamon oil from Cinnamomum zeylanicum upon early stage diabetic nephropathy
-
Mishra, A., Bhatti, R., Singh, A., Singh Ishar, M.P., Ameliorative effect of the cinnamon oil from Cinnamomum zeylanicum upon early stage diabetic nephropathy. Planta Med. 76 (2010), 412–417.
-
(2010)
Planta Med.
, vol.76
, pp. 412-417
-
-
Mishra, A.1
Bhatti, R.2
Singh, A.3
Singh Ishar, M.P.4
-
133
-
-
0033932667
-
TGF-beta signaling by Smad proteins
-
Miyazono, K., ten Dijke, P., Heldin, C.H., TGF-beta signaling by Smad proteins. Adv. Immunol. 75 (2000), 115–157.
-
(2000)
Adv. Immunol.
, vol.75
, pp. 115-157
-
-
Miyazono, K.1
ten Dijke, P.2
Heldin, C.H.3
-
134
-
-
84896070113
-
Berberine ameliorate oxidative stress and astrogliosis in the hippocampus of STZ-induced diabetic rats
-
Moghaddam, H.K., Baluchnejadmojarad, T., Roghani, M., Khaksari, M., Norouzi, P., Ahooie, M., Mahboobi, F., Berberine ameliorate oxidative stress and astrogliosis in the hippocampus of STZ-induced diabetic rats. Mol. Neurobiol. 49 (2014), 820–826.
-
(2014)
Mol. Neurobiol.
, vol.49
, pp. 820-826
-
-
Moghaddam, H.K.1
Baluchnejadmojarad, T.2
Roghani, M.3
Khaksari, M.4
Norouzi, P.5
Ahooie, M.6
Mahboobi, F.7
-
135
-
-
33748939751
-
IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
-
Moon, J.A., Kim, H.T., Cho, I.S., Sheen, Y.Y., Kim, D.K., IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy. Kidney Int. 70 (2006), 1234–1243.
-
(2006)
Kidney Int.
, vol.70
, pp. 1234-1243
-
-
Moon, J.A.1
Kim, H.T.2
Cho, I.S.3
Sheen, Y.Y.4
Kim, D.K.5
-
136
-
-
0038748305
-
Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy
-
Moriwaki, Y., Yamamoto, T., Shibutani, Y., Aoki, E., Tsutsumi, Z., Takahashi, S., Okamura, H., Koga, M., Fukuchi, M., Hada, T., Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy. Metabolism 52 (2003), 605–608.
-
(2003)
Metabolism
, vol.52
, pp. 605-608
-
-
Moriwaki, Y.1
Yamamoto, T.2
Shibutani, Y.3
Aoki, E.4
Tsutsumi, Z.5
Takahashi, S.6
Okamura, H.7
Koga, M.8
Fukuchi, M.9
Hada, T.10
-
138
-
-
0030658055
-
Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility
-
Mott, J.D., Khalifah, R.G., Nagase, H., Shield, C.F. 3rd, Hudson, J.K., Hudson, B.G., Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility. Kidney Int. 52 (1997), 1302–1312.
-
(1997)
Kidney Int.
, vol.52
, pp. 1302-1312
-
-
Mott, J.D.1
Khalifah, R.G.2
Nagase, H.3
Shield, C.F.4
Hudson, J.K.5
Hudson, B.G.6
-
139
-
-
77952646902
-
CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model
-
Mukhopadhyay, P., Pan, H., Rajesh, M., Batkai, S., Patel, V., Harvey-White, J., Mukhopadhyay, B., Hasko, G., Gao, B., Mackie, K., Pacher, P., CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. Br. J. Pharmacol. 160 (2010), 657–668.
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 657-668
-
-
Mukhopadhyay, P.1
Pan, H.2
Rajesh, M.3
Batkai, S.4
Patel, V.5
Harvey-White, J.6
Mukhopadhyay, B.7
Hasko, G.8
Gao, B.9
Mackie, K.10
Pacher, P.11
-
140
-
-
73449112234
-
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy
-
Mukhopadhyay, P., Rajesh, M., Pan, H., Patel, V., Mukhopadhyay, B., Batkai, S., Gao, B., Hasko, G., Pacher, P., Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. Free Radic. Biol. Med. 48 (2010), 457–467.
-
(2010)
Free Radic. Biol. Med.
, vol.48
, pp. 457-467
-
-
Mukhopadhyay, P.1
Rajesh, M.2
Pan, H.3
Patel, V.4
Mukhopadhyay, B.5
Batkai, S.6
Gao, B.7
Hasko, G.8
Pacher, P.9
-
141
-
-
58249110786
-
Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice
-
Murakoshi, M., Tanimoto, M., Gohda, T., Hagiwara, S., Ohara, I., Toyoda, H., Ishikawa, Y., Horikoshi, S., Tomino, Y., Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice. Diabetes Res. Clin. Pract. 83 (2009), 183–189.
-
(2009)
Diabetes Res. Clin. Pract.
, vol.83
, pp. 183-189
-
-
Murakoshi, M.1
Tanimoto, M.2
Gohda, T.3
Hagiwara, S.4
Ohara, I.5
Toyoda, H.6
Ishikawa, Y.7
Horikoshi, S.8
Tomino, Y.9
-
142
-
-
84908407280
-
Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats
-
Muthenna, P., Raghu, G., Kumar, P.A., Surekha, M.V., Reddy, G.B., Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats. Chem. Biol. Interact. 222C (2014), 68–76.
-
(2014)
Chem. Biol. Interact.
, vol.222C
, pp. 68-76
-
-
Muthenna, P.1
Raghu, G.2
Kumar, P.A.3
Surekha, M.V.4
Reddy, G.B.5
-
143
-
-
84875369328
-
Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy
-
Nagao, T., Okura, T., Irita, J., Jotoku, M., Enomoto, D., Desilva, V.R., Miyoshi, K., Kurata, M., Matsui, Y., Uede, T., Higaki, J., Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy. Nephron Extra 2 (2012), 87–103.
-
(2012)
Nephron Extra
, vol.2
, pp. 87-103
-
-
Nagao, T.1
Okura, T.2
Irita, J.3
Jotoku, M.4
Enomoto, D.5
Desilva, V.R.6
Miyoshi, K.7
Kurata, M.8
Matsui, Y.9
Uede, T.10
Higaki, J.11
-
144
-
-
31744433843
-
Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinase pathways in aldosterone/salt-induced hypertensive rats
-
Nakano, S., Kobayashi, N., Yoshida, K., Ohno, T., Matsuoka, H., Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinase pathways in aldosterone/salt-induced hypertensive rats. Hypertens. Res. 28 (2005), 925–936.
-
(2005)
Hypertens. Res.
, vol.28
, pp. 925-936
-
-
Nakano, S.1
Kobayashi, N.2
Yoshida, K.3
Ohno, T.4
Matsuoka, H.5
-
145
-
-
33845522286
-
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice
-
Ohshiro, Y., Ma, R.C., Yasuda, Y., Hiraoka-Yamamoto, J., Clermont, A.C., Isshiki, K., Yagi, K., Arikawa, E., Kern, T.S., King, G.L., Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice. Diabetes 55 (2006), 3112–3120.
-
(2006)
Diabetes
, vol.55
, pp. 3112-3120
-
-
Ohshiro, Y.1
Ma, R.C.2
Yasuda, Y.3
Hiraoka-Yamamoto, J.4
Clermont, A.C.5
Isshiki, K.6
Yagi, K.7
Arikawa, E.8
Kern, T.S.9
King, G.L.10
-
146
-
-
84871309097
-
Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression
-
Ojima, A., Ishibashi, Y., Matsui, T., Maeda, S., Nishino, Y., Takeuchi, M., Fukami, K., Yamagishi, S., Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression. Am. J. Pathol. 182 (2013), 132–141.
-
(2013)
Am. J. Pathol.
, vol.182
, pp. 132-141
-
-
Ojima, A.1
Ishibashi, Y.2
Matsui, T.3
Maeda, S.4
Nishino, Y.5
Takeuchi, M.6
Fukami, K.7
Yamagishi, S.8
-
147
-
-
84869239084
-
A novel C-C chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models
-
Okamoto, M., Fuchigami, M., Suzuki, T., Watanabe, N., A novel C-C chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models. Biol. Pharm. Bull. 35 (2012), 2069–2074.
-
(2012)
Biol. Pharm. Bull.
, vol.35
, pp. 2069-2074
-
-
Okamoto, M.1
Fuchigami, M.2
Suzuki, T.3
Watanabe, N.4
-
148
-
-
34447509674
-
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney
-
Onozato, M.L., Tojo, A., Kobayashi, N., Goto, A., Matsuoka, H., Fujita, T., Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney. Nephrol. Dial. Transplant. 22 (2007), 1314–1322.
-
(2007)
Nephrol. Dial. Transplant.
, vol.22
, pp. 1314-1322
-
-
Onozato, M.L.1
Tojo, A.2
Kobayashi, N.3
Goto, A.4
Matsuoka, H.5
Fujita, T.6
-
149
-
-
0028942726
-
Is there a role for specific anti-TNF strategies in glomerular diseases?
-
Ortiz, A., Egido, J., Is there a role for specific anti-TNF strategies in glomerular diseases?. Nephrol. Dial. Transplant. 10 (1995), 309–311.
-
(1995)
Nephrol. Dial. Transplant.
, vol.10
, pp. 309-311
-
-
Ortiz, A.1
Egido, J.2
-
150
-
-
84865959831
-
Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs
-
Osaki, T., Azuma, K., Kurozumi, S., Takamori, Y., Tsuka, T., Imagawa, T., Okamoto, Y., Minami, S., Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs. Mar. Drugs 10 (2012), 1873–1882.
-
(2012)
Mar. Drugs
, vol.10
, pp. 1873-1882
-
-
Osaki, T.1
Azuma, K.2
Kurozumi, S.3
Takamori, Y.4
Tsuka, T.5
Imagawa, T.6
Okamoto, Y.7
Minami, S.8
-
151
-
-
0036969949
-
Effect of long-term administration of prostaglandin I(2) in incipient diabetic nephropathy
-
Owada, A., Suda, S., Hata, T., Effect of long-term administration of prostaglandin I(2) in incipient diabetic nephropathy. Nephron 92 (2002), 788–796.
-
(2002)
Nephron
, vol.92
, pp. 788-796
-
-
Owada, A.1
Suda, S.2
Hata, T.3
-
152
-
-
83655201254
-
Relative incidence of ESRD versus cardiovascular mortality in proteinuric type 2 diabetes and nephropathy: results from the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) database
-
Packham, D.K., Alves, T.P., Dwyer, J.P., Atkins, R., de Zeeuw, D., Cooper, M., Shahinfar, S., Lewis, J.B., Lambers Heerspink, H.J., Relative incidence of ESRD versus cardiovascular mortality in proteinuric type 2 diabetes and nephropathy: results from the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) database. Am. J. Kidney Dis. 59 (2012), 75–83.
-
(2012)
Am. J. Kidney Dis.
, vol.59
, pp. 75-83
-
-
Packham, D.K.1
Alves, T.P.2
Dwyer, J.P.3
Atkins, R.4
de Zeeuw, D.5
Cooper, M.6
Shahinfar, S.7
Lewis, J.B.8
Lambers Heerspink, H.J.9
-
153
-
-
84894206382
-
Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice
-
Pan, Y., Zhang, X., Wang, Y., Cai, L., Ren, L., Tang, L., Wang, J., Zhao, Y., Wang, Y., Liu, Q., Li, X., Liang, G., Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice. PloS One, 8, 2013, e79084.
-
(2013)
PloS One
, vol.8
, pp. e79084
-
-
Pan, Y.1
Zhang, X.2
Wang, Y.3
Cai, L.4
Ren, L.5
Tang, L.6
Wang, J.7
Zhao, Y.8
Wang, Y.9
Liu, Q.10
Li, X.11
Liang, G.12
-
154
-
-
33745313224
-
Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha
-
Park, C.W., Kim, H.W., Ko, S.H., Chung, H.W., Lim, S.W., Yang, C.W., Chang, Y.S., Sugawara, A., Guan, Y., Breyer, M.D., Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha. Diabetes 55 (2006), 885–893.
-
(2006)
Diabetes
, vol.55
, pp. 885-893
-
-
Park, C.W.1
Kim, H.W.2
Ko, S.H.3
Chung, H.W.4
Lim, S.W.5
Yang, C.W.6
Chang, Y.S.7
Sugawara, A.8
Guan, Y.9
Breyer, M.D.10
-
155
-
-
84862743206
-
MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes
-
Park, S.K., Dahmer, M.K., Quasney, M.W., MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes. Cell Physiol. Biochem. 30 (2012), 334–346.
-
(2012)
Cell Physiol. Biochem.
, vol.30
, pp. 334-346
-
-
Park, S.K.1
Dahmer, M.K.2
Quasney, M.W.3
-
156
-
-
0034773498
-
Diabetic nephropathy: prevention and treatment
-
Parving, H.H., Diabetic nephropathy: prevention and treatment. Kidney Int. 60 (2001), 2041–2055.
-
(2001)
Kidney Int.
, vol.60
, pp. 2041-2055
-
-
Parving, H.H.1
-
157
-
-
25144455142
-
Region-specific alterations of adenosine receptors expression level in kidney of diabetic rat
-
Pawelczyk, T., Grden, M., Rzepko, R., Sakowicz, M., Szutowicz, A., Region-specific alterations of adenosine receptors expression level in kidney of diabetic rat. Am. J. Pathol. 167 (2005), 315–325.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 315-325
-
-
Pawelczyk, T.1
Grden, M.2
Rzepko, R.3
Sakowicz, M.4
Szutowicz, A.5
-
158
-
-
40049099699
-
Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis
-
Petersen, M., Thorikay, M., Deckers, M., van Dinther, M., Grygielko, E.T., Gellibert, F., de Gouville, A.C., Huet, S., ten Dijke, P., Laping, N.J., Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis. Kidney Int. 73 (2008), 705–715.
-
(2008)
Kidney Int.
, vol.73
, pp. 705-715
-
-
Petersen, M.1
Thorikay, M.2
Deckers, M.3
van Dinther, M.4
Grygielko, E.T.5
Gellibert, F.6
de Gouville, A.C.7
Huet, S.8
ten Dijke, P.9
Laping, N.J.10
-
159
-
-
0032763469
-
Specificity, diversity, and regulation in TGF-beta superfamily signaling
-
Piek, E., Heldin, C.H., Ten Dijke, P., Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J. 13 (1999), 2105–2124.
-
(1999)
FASEB J.
, vol.13
, pp. 2105-2124
-
-
Piek, E.1
Heldin, C.H.2
Ten Dijke, P.3
-
160
-
-
0742270609
-
P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli
-
Porras, A., Zuluaga, S., Black, E., Valladares, A., Alvarez, A.M., Ambrosino, C., Benito, M., Nebreda, A.R., P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol. Biol. Cell 15 (2004), 922–933.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 922-933
-
-
Porras, A.1
Zuluaga, S.2
Black, E.3
Valladares, A.4
Alvarez, A.M.5
Ambrosino, C.6
Benito, M.7
Nebreda, A.R.8
-
161
-
-
84868134298
-
Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: possible implication in ocular neovascularization
-
Puddu, A., Sanguineti, R., Durante, A., Nicolo, M., Viviani, G.L., Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: possible implication in ocular neovascularization. Mol. Vis. 18 (2012), 2509–2517.
-
(2012)
Mol. Vis.
, vol.18
, pp. 2509-2517
-
-
Puddu, A.1
Sanguineti, R.2
Durante, A.3
Nicolo, M.4
Viviani, G.L.5
-
162
-
-
17944369113
-
Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice
-
Pugliese, G., Pricci, F., Iacobini, C., Leto, G., Amadio, L., Barsotti, P., Frigeri, L., Hsu, D.K., Vlassara, H., Liu, F.T., Di Mario, U., Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice. FASEB J. : Off. Publ. Fed. Am. Soc. Exp. Biol. 15 (2001), 2471–2479.
-
(2001)
FASEB J. : Off. Publ. Fed. Am. Soc. Exp. Biol.
, vol.15
, pp. 2471-2479
-
-
Pugliese, G.1
Pricci, F.2
Iacobini, C.3
Leto, G.4
Amadio, L.5
Barsotti, P.6
Frigeri, L.7
Hsu, D.K.8
Vlassara, H.9
Liu, F.T.10
Di Mario, U.11
-
163
-
-
80054054044
-
Aldose reductase: new insights for an old enzyme
-
Ramana, K.V., Aldose reductase: new insights for an old enzyme. Biomol. Concepts 2 (2011), 103–114.
-
(2011)
Biomol. Concepts
, vol.2
, pp. 103-114
-
-
Ramana, K.V.1
-
164
-
-
74049097246
-
Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy
-
Rane, M.J., Song, Y., Jin, S., Barati, M.T., Wu, R., Kausar, H., Tan, Y., Wang, Y., Zhou, G., Klein, J.B., Li, X., Cai, L., Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy. Am. J. Physiol. Ren. Physiol. 298 (2010), F49–F61.
-
(2010)
Am. J. Physiol. Ren. Physiol.
, vol.298
, pp. F49-F61
-
-
Rane, M.J.1
Song, Y.2
Jin, S.3
Barati, M.T.4
Wu, R.5
Kausar, H.6
Tan, Y.7
Wang, Y.8
Zhou, G.9
Klein, J.B.10
Li, X.11
Cai, L.12
-
165
-
-
49649125932
-
Effect of green tea on kidney tubules of diabetic rats
-
Renno, W.M., Abdeen, S., Alkhalaf, M., Asfar, S., Effect of green tea on kidney tubules of diabetic rats. Br. J. Nutr. 100 (2008), 652–659.
-
(2008)
Br. J. Nutr.
, vol.100
, pp. 652-659
-
-
Renno, W.M.1
Abdeen, S.2
Alkhalaf, M.3
Asfar, S.4
-
166
-
-
33845388491
-
Diabetic nephropathy: worldwide epidemic and effects of current treatment on natural history
-
Rossing, P., Diabetic nephropathy: worldwide epidemic and effects of current treatment on natural history. Curr. Diab Rep. 6 (2006), 479–483.
-
(2006)
Curr. Diab Rep.
, vol.6
, pp. 479-483
-
-
Rossing, P.1
-
167
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
-
Roux, P.P., Blenis, J., ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol. Biol. Rev. 68 (2004), 320–344.
-
(2004)
Microbiol Mol. Biol. Rev.
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
168
-
-
84942248274
-
Hypoglycemic action of vitamin K1 protects against early-onset diabetic nephropathy in streptozotocin-induced rats
-
Sai Varsha, M.K., Raman, T., Manikandan, R., Dhanasekaran, G., Hypoglycemic action of vitamin K1 protects against early-onset diabetic nephropathy in streptozotocin-induced rats. Nutrition 31 (2015), 1284–1292.
-
(2015)
Nutrition
, vol.31
, pp. 1284-1292
-
-
Sai Varsha, M.K.1
Raman, T.2
Manikandan, R.3
Dhanasekaran, G.4
-
169
-
-
19944396117
-
Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy
-
Sakai, N., Wada, T., Furuichi, K., Iwata, Y., Yoshimoto, K., Kitagawa, K., Kokubo, S., Kobayashi, M., Hara, A., Yamahana, J., Okumura, T., Takasawa, K., Takeda, S., Yoshimura, M., Kida, H., Yokoyama, H., Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy. Am. J. Kidney Dis. 45 (2005), 54–65.
-
(2005)
Am. J. Kidney Dis.
, vol.45
, pp. 54-65
-
-
Sakai, N.1
Wada, T.2
Furuichi, K.3
Iwata, Y.4
Yoshimoto, K.5
Kitagawa, K.6
Kokubo, S.7
Kobayashi, M.8
Hara, A.9
Yamahana, J.10
Okumura, T.11
Takasawa, K.12
Takeda, S.13
Yoshimura, M.14
Kida, H.15
Yokoyama, H.16
-
170
-
-
84860630975
-
Targeting the interleukin-6/Jak/stat pathway in human malignancies
-
Sansone, P., Bromberg, J., Targeting the interleukin-6/Jak/stat pathway in human malignancies. J. Clin. Oncol. 30 (2012), 1005–1014.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 1005-1014
-
-
Sansone, P.1
Bromberg, J.2
-
171
-
-
38349057990
-
Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin
-
Sataranatarajan, K., Mariappan, M.M., Lee, M.J., Feliers, D., Choudhury, G.G., Barnes, J.L., Kasinath, B.S., Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin. Am. J. Pathol. 171 (2007), 1733–1742.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1733-1742
-
-
Sataranatarajan, K.1
Mariappan, M.M.2
Lee, M.J.3
Feliers, D.4
Choudhury, G.G.5
Barnes, J.L.6
Kasinath, B.S.7
-
172
-
-
84858765166
-
Novel insights into the relationship between glomerular pathology and progressive kidney disease
-
Satirapoj, B., Nast, C.C., Adler, S.G., Novel insights into the relationship between glomerular pathology and progressive kidney disease. Adv. Chronic Kidney Dis. 19 (2012), 93–100.
-
(2012)
Adv. Chronic Kidney Dis.
, vol.19
, pp. 93-100
-
-
Satirapoj, B.1
Nast, C.C.2
Adler, S.G.3
-
173
-
-
0034836835
-
Apoptosis in podocytes induced by TGF-beta and Smad7
-
Schiffer, M., Bitzer, M., Roberts, I.S., Kopp, J.B., ten Dijke, P., Mundel, P., Bottinger, E.P., Apoptosis in podocytes induced by TGF-beta and Smad7. J. Clin. Invest 108 (2001), 807–816.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 807-816
-
-
Schiffer, M.1
Bitzer, M.2
Roberts, I.S.3
Kopp, J.B.4
ten Dijke, P.5
Mundel, P.6
Bottinger, E.P.7
-
174
-
-
84871819023
-
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes
-
Sedeek, M., Gutsol, A., Montezano, A.C., Burger, D., Nguyen Dinh Cat, A., Kennedy, C.R., Burns, K.D., Cooper, M.E., Jandeleit-Dahm, K., Page, P., Szyndralewiez, C., Heitz, F., Hebert, R.L., Touyz, R.M., Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes. Clin. Sci. (Lond.) 124 (2013), 191–202.
-
(2013)
Clin. Sci. (Lond.)
, vol.124
, pp. 191-202
-
-
Sedeek, M.1
Gutsol, A.2
Montezano, A.C.3
Burger, D.4
Nguyen Dinh Cat, A.5
Kennedy, C.R.6
Burns, K.D.7
Cooper, M.E.8
Jandeleit-Dahm, K.9
Page, P.10
Szyndralewiez, C.11
Heitz, F.12
Hebert, R.L.13
Touyz, R.M.14
-
175
-
-
63849160230
-
Molecular mechanisms of hypertension: role of Nox family NADPH oxidases
-
Sedeek, M., Hebert, R.L., Kennedy, C.R., Burns, K.D., Touyz, R.M., Molecular mechanisms of hypertension: role of Nox family NADPH oxidases. Curr. Opin. Nephrol. Hypertens. 18 (2009), 122–127.
-
(2009)
Curr. Opin. Nephrol. Hypertens.
, vol.18
, pp. 122-127
-
-
Sedeek, M.1
Hebert, R.L.2
Kennedy, C.R.3
Burns, K.D.4
Touyz, R.M.5
-
176
-
-
0038299000
-
Sirolimus: its discovery, biological properties, and mechanism of action
-
Sehgal, S.N., Sirolimus: its discovery, biological properties, and mechanism of action. Transplant. Proc. 35 (2003), 7s–14s.
-
(2003)
Transplant. Proc.
, vol.35
, pp. 7s-14s
-
-
Sehgal, S.N.1
-
177
-
-
38849203158
-
Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276
-
Seldon, M.P., Silva, G., Pejanovic, N., Larsen, R., Gregoire, I.P., Filipe, J., Anrather, J., Soares, M.P., Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276. J. Immunol. 179 (2007), 7840–7851.
-
(2007)
J. Immunol.
, vol.179
, pp. 7840-7851
-
-
Seldon, M.P.1
Silva, G.2
Pejanovic, N.3
Larsen, R.4
Gregoire, I.P.5
Filipe, J.6
Anrather, J.7
Soares, M.P.8
-
178
-
-
57049099165
-
Ciglitazone, a PPARgamma agonist, ameliorates diabetic nephropathy in part through homocysteine clearance
-
Sen, U., Rodriguez, W.E., Tyagi, N., Kumar, M., Kundu, S., Tyagi, S.C., Ciglitazone, a PPARgamma agonist, ameliorates diabetic nephropathy in part through homocysteine clearance. Am. J. Physiol. Endocrinol. Metab. 295 (2008), E1205–E1212.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, pp. E1205-E1212
-
-
Sen, U.1
Rodriguez, W.E.2
Tyagi, N.3
Kumar, M.4
Kundu, S.5
Tyagi, S.C.6
-
179
-
-
33745570504
-
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
-
Shahbazian, D., Roux, P.P., Mieulet, V., Cohen, M.S., Raught, B., Taunton, J., Hershey, J.W., Blenis, J., Pende, M., Sonenberg, N., The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J. 25 (2006), 2781–2791.
-
(2006)
EMBO J.
, vol.25
, pp. 2781-2791
-
-
Shahbazian, D.1
Roux, P.P.2
Mieulet, V.3
Cohen, M.S.4
Raught, B.5
Taunton, J.6
Hershey, J.W.7
Blenis, J.8
Pende, M.9
Sonenberg, N.10
-
180
-
-
0029808386
-
Differential expression of transforming growth factor-beta isoforms and receptors in experimental membranous nephropathy
-
Shankland, S.J., Pippin, J., Pichler, R.H., Gordon, K.L., Friedman, S., Gold, L.I., Johnson, R.J., Couser, W.G., Differential expression of transforming growth factor-beta isoforms and receptors in experimental membranous nephropathy. Kidney Int 50 (1996), 116–124.
-
(1996)
Kidney Int
, vol.50
, pp. 116-124
-
-
Shankland, S.J.1
Pippin, J.2
Pichler, R.H.3
Gordon, K.L.4
Friedman, S.5
Gold, L.I.6
Johnson, R.J.7
Couser, W.G.8
-
181
-
-
36649027456
-
Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions
-
Shi, Y.H., Zhao, S., Wang, C., Li, Y., Duan, H.J., Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions. Acta Pharm. Sin. 28 (2007), 1938–1946.
-
(2007)
Acta Pharm. Sin.
, vol.28
, pp. 1938-1946
-
-
Shi, Y.H.1
Zhao, S.2
Wang, C.3
Li, Y.4
Duan, H.J.5
-
182
-
-
33846443625
-
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1
-
Shibata, S., Nagase, M., Yoshida, S., Kawachi, H., Fujita, T., Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 49 (2007), 355–364.
-
(2007)
Hypertension
, vol.49
, pp. 355-364
-
-
Shibata, S.1
Nagase, M.2
Yoshida, S.3
Kawachi, H.4
Fujita, T.5
-
183
-
-
80555123045
-
Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications
-
Singh, B.N., Shankar, S., Srivastava, R.K., Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharm. 82 (2011), 1807–1821.
-
(2011)
Biochem Pharm.
, vol.82
, pp. 1807-1821
-
-
Singh, B.N.1
Shankar, S.2
Srivastava, R.K.3
-
184
-
-
41749123049
-
Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production
-
Singh, V.P., Baker, K.M., Kumar, R., Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production. Am. J. Physiol. Heart Circ. Physiol. 294 (2008), H1675–H1684.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.294
, pp. H1675-H1684
-
-
Singh, V.P.1
Baker, K.M.2
Kumar, R.3
-
185
-
-
21244480367
-
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
-
Smith, E.M., Finn, S.G., Tee, A.R., Browne, G.J., Proud, C.G., The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. J. Biol. Chem. 280 (2005), 18717–18727.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18717-18727
-
-
Smith, E.M.1
Finn, S.G.2
Tee, A.R.3
Browne, G.J.4
Proud, C.G.5
-
186
-
-
74249100627
-
Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction
-
Song, J., Eyster, K.M., Kost, C.K. Jr., Kjellsen, B., Martin, D.S., Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction. Cardiovasc Res 85 (2010), 614–621.
-
(2010)
Cardiovasc Res
, vol.85
, pp. 614-621
-
-
Song, J.1
Eyster, K.M.2
Kost, C.K.3
Kjellsen, B.4
Martin, D.S.5
-
187
-
-
55949109631
-
Structural basis of protein kinase C isoform function
-
Steinberg, S.F., Structural basis of protein kinase C isoform function. Physiol. Rev. 88 (2008), 1341–1378.
-
(2008)
Physiol. Rev.
, vol.88
, pp. 1341-1378
-
-
Steinberg, S.F.1
-
188
-
-
33646035513
-
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells
-
Stielow, C., Catar, R.A., Muller, G., Wingler, K., Scheurer, P., Schmidt, H.H., Morawietz, H., Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells. Biochem Biophys. Res Commun. 344 (2006), 200–205.
-
(2006)
Biochem Biophys. Res Commun.
, vol.344
, pp. 200-205
-
-
Stielow, C.1
Catar, R.A.2
Muller, G.3
Wingler, K.4
Scheurer, P.5
Schmidt, H.H.6
Morawietz, H.7
-
189
-
-
84876500601
-
Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease
-
Streeter, J., Thiel, W., Brieger, K., Miller, F.J. Jr., Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. Cardiovasc Ther. 31 (2013), 125–137.
-
(2013)
Cardiovasc Ther.
, vol.31
, pp. 125-137
-
-
Streeter, J.1
Thiel, W.2
Brieger, K.3
Miller, F.J.4
-
190
-
-
33745066911
-
Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells
-
Su, Z., Zimpelmann, J., Burns, K.D., Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells. Kidney Int. 69 (2006), 2212–2218.
-
(2006)
Kidney Int.
, vol.69
, pp. 2212-2218
-
-
Su, Z.1
Zimpelmann, J.2
Burns, K.D.3
-
191
-
-
84863886684
-
Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications
-
Sullivan, T.J., Dairaghi, D.J., Krasinski, A., Miao, Z., Wang, Y., Zhao, B.N., Baumgart, T., Berahovich, R., Ertl, L.S., Pennell, A., Seitz, L., Miao, S., Ungashe, S., Wei, Z., Johnson, D., Boring, L., Tsou, C.L., Charo, I.F., Bekker, P., Schall, T.J., Jaen, J.C., Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications. J. Pharm. Exp. Ther., 2012.
-
(2012)
J. Pharm. Exp. Ther.
-
-
Sullivan, T.J.1
Dairaghi, D.J.2
Krasinski, A.3
Miao, Z.4
Wang, Y.5
Zhao, B.N.6
Baumgart, T.7
Berahovich, R.8
Ertl, L.S.9
Pennell, A.10
Seitz, L.11
Miao, S.12
Ungashe, S.13
Wei, Z.14
Johnson, D.15
Boring, L.16
Tsou, C.L.17
Charo, I.F.18
Bekker, P.19
Schall, T.J.20
Jaen, J.C.21
more..
-
192
-
-
33644783770
-
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
-
Susztak, K., Raff, A.C., Schiffer, M., Bottinger, E.P., Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55 (2006), 225–233.
-
(2006)
Diabetes
, vol.55
, pp. 225-233
-
-
Susztak, K.1
Raff, A.C.2
Schiffer, M.3
Bottinger, E.P.4
-
193
-
-
0033113321
-
Carbonyl stress in the pathogenesis of diabetic nephropathy
-
Suzuki, D., Miyata, T., Carbonyl stress in the pathogenesis of diabetic nephropathy. Intern Med 38 (1999), 309–314.
-
(1999)
Intern Med
, vol.38
, pp. 309-314
-
-
Suzuki, D.1
Miyata, T.2
-
194
-
-
0033055417
-
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions
-
Suzuki, D., Miyata, T., Saotome, N., Horie, K., Inagi, R., Yasuda, Y., Uchida, K., Izuhara, Y., Yagame, M., Sakai, H., Kurokawa, K., Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions. J. Am. Soc. Nephrol. 10 (1999), 822–832.
-
(1999)
J. Am. Soc. Nephrol.
, vol.10
, pp. 822-832
-
-
Suzuki, D.1
Miyata, T.2
Saotome, N.3
Horie, K.4
Inagi, R.5
Yasuda, Y.6
Uchida, K.7
Izuhara, Y.8
Yagame, M.9
Sakai, H.10
Kurokawa, K.11
-
195
-
-
7044272697
-
Role of mitogen-activated protein kinase in the regulation of transforming growth factor-beta-induced fibronectin accumulation in cultured renal interstitial fibroblasts
-
Suzuki, H., Uchida, K., Nitta, K., Nihei, H., Role of mitogen-activated protein kinase in the regulation of transforming growth factor-beta-induced fibronectin accumulation in cultured renal interstitial fibroblasts. Clin. Exp. Nephrol. 8 (2004), 188–195.
-
(2004)
Clin. Exp. Nephrol.
, vol.8
, pp. 188-195
-
-
Suzuki, H.1
Uchida, K.2
Nitta, K.3
Nihei, H.4
-
196
-
-
84878660732
-
Tnt1 retrotransposon tagging of STF in Medicago truncatula reveals tight coordination of metabolic, hormonal and developmental signals during leaf morphogenesis
-
Tadege, M., Mysore, K.S., Tnt1 retrotransposon tagging of STF in Medicago truncatula reveals tight coordination of metabolic, hormonal and developmental signals during leaf morphogenesis. Mob. Genet Elem. 1 (2011), 301–303.
-
(2011)
Mob. Genet Elem.
, vol.1
, pp. 301-303
-
-
Tadege, M.1
Mysore, K.S.2
-
197
-
-
0038069126
-
High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells
-
Takaishi, H., Taniguchi, T., Takahashi, A., Ishikawa, Y., Yokoyama, M., High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells. Biochem Biophys. Res Commun. 305 (2003), 122–128.
-
(2003)
Biochem Biophys. Res Commun.
, vol.305
, pp. 122-128
-
-
Takaishi, H.1
Taniguchi, T.2
Takahashi, A.3
Ishikawa, Y.4
Yokoyama, M.5
-
198
-
-
33645890286
-
Role of advanced glycation end products (AGEs) in thrombogenic abnormalities in diabetes
-
Takenaka, K., Yamagishi, S., Matsui, T., Nakamura, K., Imaizumi, T., Role of advanced glycation end products (AGEs) in thrombogenic abnormalities in diabetes. Curr. neurovascular Res. 3 (2006), 73–77.
-
(2006)
Curr. neurovascular Res.
, vol.3
, pp. 73-77
-
-
Takenaka, K.1
Yamagishi, S.2
Matsui, T.3
Nakamura, K.4
Imaizumi, T.5
-
199
-
-
84897107588
-
Potential approaches to reverse or repair renal fibrosis
-
Tampe, D., Zeisberg, M., Potential approaches to reverse or repair renal fibrosis. Nat. Rev. Nephrol. 10 (2014), 226–237.
-
(2014)
Nat. Rev. Nephrol.
, vol.10
, pp. 226-237
-
-
Tampe, D.1
Zeisberg, M.2
-
200
-
-
77950601556
-
Pathologic classification of diabetic nephropathy
-
Tervaert, T.W., Mooyaart, A.L., Amann, K., Cohen, A.H., Cook, H.T., Drachenberg, C.B., Ferrario, F., Fogo, A.B., Haas, M., de Heer, E., Joh, K., Noel, L.H., Radhakrishnan, J., Seshan, S.V., Bajema, I.M., Bruijn, J.A., Pathologic classification of diabetic nephropathy. J. Am. Soc. Nephrol. 21 (2010), 556–563.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 556-563
-
-
Tervaert, T.W.1
Mooyaart, A.L.2
Amann, K.3
Cohen, A.H.4
Cook, H.T.5
Drachenberg, C.B.6
Ferrario, F.7
Fogo, A.B.8
Haas, M.9
de Heer, E.10
Joh, K.11
Noel, L.H.12
Radhakrishnan, J.13
Seshan, S.V.14
Bajema, I.M.15
Bruijn, J.A.16
-
201
-
-
85003726485
-
Nox-4 deletion reduces oxidative stress and injury by PKC-alpha-associated mechanisms in diabetic nephropathy
-
Thallas-Bonke, V., Jha, J.C., Gray, S.P., Barit, D., Haller, H., Schmidt, H.H., Coughlan, M.T., Cooper, M.E., Forbes, J.M., Jandeleit-Dahm, K.A., Nox-4 deletion reduces oxidative stress and injury by PKC-alpha-associated mechanisms in diabetic nephropathy. Physiol. Rep., 2, 2014.
-
(2014)
Physiol. Rep.
, vol.2
-
-
Thallas-Bonke, V.1
Jha, J.C.2
Gray, S.P.3
Barit, D.4
Haller, H.5
Schmidt, H.H.6
Coughlan, M.T.7
Cooper, M.E.8
Forbes, J.M.9
Jandeleit-Dahm, K.A.10
-
202
-
-
40749139536
-
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway
-
Thallas-Bonke, V., Thorpe, S.R., Coughlan, M.T., Fukami, K., Yap, F.Y., Sourris, K.C., Penfold, S.A., Bach, L.A., Cooper, M.E., Forbes, J.M., Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway. Diabetes 57 (2008), 460–469.
-
(2008)
Diabetes
, vol.57
, pp. 460-469
-
-
Thallas-Bonke, V.1
Thorpe, S.R.2
Coughlan, M.T.3
Fukami, K.4
Yap, F.Y.5
Sourris, K.C.6
Penfold, S.A.7
Bach, L.A.8
Cooper, M.E.9
Forbes, J.M.10
-
203
-
-
28044449557
-
Advanced glycation end products and diabetic nephropathy
-
Thomas, M.C., Forbes, J.M., Cooper, M.E., Advanced glycation end products and diabetic nephropathy. Am. J. Ther. 12 (2005), 562–572.
-
(2005)
Am. J. Ther.
, vol.12
, pp. 562-572
-
-
Thomas, M.C.1
Forbes, J.M.2
Cooper, M.E.3
-
204
-
-
57049159229
-
Diabetes-induced upregulation of urotensin II and its receptor plays an important role in TGF-beta1-mediated renal fibrosis and dysfunction
-
Tian, L., Li, C., Qi, J., Fu, P., Yu, X., Li, X., Cai, L., Diabetes-induced upregulation of urotensin II and its receptor plays an important role in TGF-beta1-mediated renal fibrosis and dysfunction. Am. J. Physiol. Endocrinol. Metab. 295 (2008), E1234–E1242.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, pp. E1234-E1242
-
-
Tian, L.1
Li, C.2
Qi, J.3
Fu, P.4
Yu, X.5
Li, X.6
Cai, L.7
-
205
-
-
84906082309
-
Calorie restriction mimicking effects of roflumilast prevents diabetic nephropathy
-
Tikoo, K., Lodea, S., Karpe, P.A., Kumar, S., Calorie restriction mimicking effects of roflumilast prevents diabetic nephropathy. Biochem Biophys. Res Commun. 450 (2014), 1581–1586.
-
(2014)
Biochem Biophys. Res Commun.
, vol.450
, pp. 1581-1586
-
-
Tikoo, K.1
Lodea, S.2
Karpe, P.A.3
Kumar, S.4
-
206
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
Tournier, C., Hess, P., Yang, D.D., Xu, J., Turner, T.K., Nimnual, A., Bar-Sagi, D., Jones, S.N., Flavell, R.A., Davis, R.J., Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Sci. (New Y., N. Y. ) 288 (2000), 870–874.
-
(2000)
Sci. (New Y., N. Y.)
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
207
-
-
57149094230
-
Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis
-
Tracz, M.J., Juncos, J.P., Grande, J.P., Croatt, A.J., Ackerman, A.W., Katusic, Z.S., Nath, K.A., Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis. Am. J. Pathol. 173 (2008), 1882–1890.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 1882-1890
-
-
Tracz, M.J.1
Juncos, J.P.2
Grande, J.P.3
Croatt, A.J.4
Ackerman, A.W.5
Katusic, Z.S.6
Nath, K.A.7
-
208
-
-
28644442122
-
The effect of ruboxistaurin on nephropathy in type 2 diabetes
-
Tuttle, K.R., Bakris, G.L., Toto, R.D., McGill, J.B., Hu, K., Anderson, P.W., The effect of ruboxistaurin on nephropathy in type 2 diabetes. Diabetes Care 28 (2005), 2686–2690.
-
(2005)
Diabetes Care
, vol.28
, pp. 2686-2690
-
-
Tuttle, K.R.1
Bakris, G.L.2
Toto, R.D.3
McGill, J.B.4
Hu, K.5
Anderson, P.W.6
-
209
-
-
77953061313
-
Advanced glycation end products in foods and a practical guide to their reduction in the diet
-
e912
-
Uribarri, J., Woodruff, S., Goodman, S., Cai, W., Chen, X., Pyzik, R., Yong, A., Striker, G.E., Vlassara, H., Advanced glycation end products in foods and a practical guide to their reduction in the diet. J. Am. Diet. Assoc. 110 (2010), 911–916 e912.
-
(2010)
J. Am. Diet. Assoc.
, vol.110
, pp. 911-916
-
-
Uribarri, J.1
Woodruff, S.2
Goodman, S.3
Cai, W.4
Chen, X.5
Pyzik, R.6
Yong, A.7
Striker, G.E.8
Vlassara, H.9
-
210
-
-
0037636775
-
C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
-
Utsugi, M., Dobashi, K., Ishizuka, T., Masubuchi, K., Shimizu, Y., Nakazawa, T., Mori, M., C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 28 (2003), 754–761.
-
(2003)
Am. J. Respir. Cell Mol. Biol.
, vol.28
, pp. 754-761
-
-
Utsugi, M.1
Dobashi, K.2
Ishizuka, T.3
Masubuchi, K.4
Shimizu, Y.5
Nakazawa, T.6
Mori, M.7
-
211
-
-
1642422399
-
Gene expression of adenosine receptors along the nephron
-
Vitzthum, H., Weiss, B., Bachleitner, W., Kramer, B.K., Kurtz, A., Gene expression of adenosine receptors along the nephron. Kidney Int 65 (2004), 1180–1190.
-
(2004)
Kidney Int
, vol.65
, pp. 1180-1190
-
-
Vitzthum, H.1
Weiss, B.2
Bachleitner, W.3
Kramer, B.K.4
Kurtz, A.5
-
212
-
-
77951497845
-
Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy
-
Vogt, L., Chiurchiu, C., Chadha-Boreham, H., Danaietash, P., Dingemanse, J., Hadjadj, S., Krum, H., Navis, G., Neuhart, E., Parvanova, A.I., Ruggenenti, P., Woittiez, A.J., Zimlichman, R., Remuzzi, G., de Zeeuw, D., Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy. Hypertension 55 (2010), 1206–1209.
-
(2010)
Hypertension
, vol.55
, pp. 1206-1209
-
-
Vogt, L.1
Chiurchiu, C.2
Chadha-Boreham, H.3
Danaietash, P.4
Dingemanse, J.5
Hadjadj, S.6
Krum, H.7
Navis, G.8
Neuhart, E.9
Parvanova, A.I.10
Ruggenenti, P.11
Woittiez, A.J.12
Zimlichman, R.13
Remuzzi, G.14
de Zeeuw, D.15
-
213
-
-
23744514571
-
Pyridoxamine: the many virtues of a maillard reaction inhibitor
-
Voziyan, P.A., Hudson, B.G., Pyridoxamine: the many virtues of a maillard reaction inhibitor. Ann. N Y Acad. Sci. 1043 (2005), 807–816.
-
(2005)
Ann. N Y Acad. Sci.
, vol.1043
, pp. 807-816
-
-
Voziyan, P.A.1
Hudson, B.G.2
-
214
-
-
28444461820
-
Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli
-
Wahab, N.A., Schaefer, L., Weston, B.S., Yiannikouris, O., Wright, A., Babelova, A., Schaefer, R., Mason, R.M., Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli. Diabetologia 48 (2005), 2650–2660.
-
(2005)
Diabetologia
, vol.48
, pp. 2650-2660
-
-
Wahab, N.A.1
Schaefer, L.2
Weston, B.S.3
Yiannikouris, O.4
Wright, A.5
Babelova, A.6
Schaefer, R.7
Mason, R.M.8
-
215
-
-
81155150123
-
Canonical Wnt/beta-catenin signaling mediates transforming growth factor-beta1-driven podocyte injury and proteinuria
-
Wang, D., Dai, C., Li, Y., Liu, Y., Canonical Wnt/beta-catenin signaling mediates transforming growth factor-beta1-driven podocyte injury and proteinuria. Kidney Int 80 (2011), 1159–1169.
-
(2011)
Kidney Int
, vol.80
, pp. 1159-1169
-
-
Wang, D.1
Dai, C.2
Li, Y.3
Liu, Y.4
-
216
-
-
0036094915
-
Inhibition of c-Jun N-terminal kinase ameliorates apoptosis induced by hydrogen peroxide in the kidney tubule epithelial cells (NRK-52E)
-
Wang, L., Matsushita, K., Araki, I., Takeda, M., Inhibition of c-Jun N-terminal kinase ameliorates apoptosis induced by hydrogen peroxide in the kidney tubule epithelial cells (NRK-52E). Nephron 91 (2002), 142–147.
-
(2002)
Nephron
, vol.91
, pp. 142-147
-
-
Wang, L.1
Matsushita, K.2
Araki, I.3
Takeda, M.4
-
217
-
-
84863023552
-
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells
-
Wang, W., Wang, Y., Long, J., Wang, J., Haudek, S.B., Overbeek, P., Chang, B.H., Schumacker, P.T., Danesh, F.R., Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab. 15 (2012), 186–200.
-
(2012)
Cell Metab.
, vol.15
, pp. 186-200
-
-
Wang, W.1
Wang, Y.2
Long, J.3
Wang, J.4
Haudek, S.B.5
Overbeek, P.6
Chang, B.H.7
Schumacker, P.T.8
Danesh, F.R.9
-
218
-
-
0036894194
-
Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells
-
Wang, X., Shaw, S., Amiri, F., Eaton, D.C., Marrero, M.B., Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells. Diabetes 51 (2002), 3505–3509.
-
(2002)
Diabetes
, vol.51
, pp. 3505-3509
-
-
Wang, X.1
Shaw, S.2
Amiri, F.3
Eaton, D.C.4
Marrero, M.B.5
-
219
-
-
36849053427
-
The role of sulodexide in the treatment of diabetic nephropathy
-
Weiss, R., Niecestro, R., Raz, I., The role of sulodexide in the treatment of diabetic nephropathy. Drugs 67 (2007), 2681–2696.
-
(2007)
Drugs
, vol.67
, pp. 2681-2696
-
-
Weiss, R.1
Niecestro, R.2
Raz, I.3
-
220
-
-
62149126622
-
Avosentan reduces albumin excretion in diabetics with macroalbuminuria
-
Wenzel, R.R., Littke, T., Kuranoff, S., Jurgens, C., Bruck, H., Ritz, E., Philipp, T., Mitchell, A., Avosentan reduces albumin excretion in diabetics with macroalbuminuria. J. Am. Soc. Nephrol. 20 (2009), 655–664.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 655-664
-
-
Wenzel, R.R.1
Littke, T.2
Kuranoff, S.3
Jurgens, C.4
Bruck, H.5
Ritz, E.6
Philipp, T.7
Mitchell, A.8
-
221
-
-
0033729838
-
Control of the eukaryotic cell cycle by MAP kinase signaling pathways
-
Wilkinson, M.G., Millar, J.B., Control of the eukaryotic cell cycle by MAP kinase signaling pathways. FASEB J. 14 (2000), 2147–2157.
-
(2000)
FASEB J.
, vol.14
, pp. 2147-2157
-
-
Wilkinson, M.G.1
Millar, J.B.2
-
222
-
-
0035720552
-
Chronic exposure of human mesangial cells to high glucose environments activates the p38 MAPK pathway
-
Wilmer, W.A., Dixon, C.L., Hebert, C., Chronic exposure of human mesangial cells to high glucose environments activates the p38 MAPK pathway. Kidney Int 60 (2001), 858–871.
-
(2001)
Kidney Int
, vol.60
, pp. 858-871
-
-
Wilmer, W.A.1
Dixon, C.L.2
Hebert, C.3
-
223
-
-
67649616517
-
Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat
-
Wittmann, S., Daniel, C., Stief, A., Vogelbacher, R., Amann, K., Hugo, C., Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat. Transplantation 87 (2009), 1290–1299.
-
(2009)
Transplantation
, vol.87
, pp. 1290-1299
-
-
Wittmann, S.1
Daniel, C.2
Stief, A.3
Vogelbacher, R.4
Amann, K.5
Hugo, C.6
-
224
-
-
10644277302
-
New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology
-
Wolf, G., New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. Eur. J. Clin. Invest 34 (2004), 785–796.
-
(2004)
Eur. J. Clin. Invest
, vol.34
, pp. 785-796
-
-
Wolf, G.1
-
225
-
-
0042378825
-
Erk 1,2 phosphorylates p27(Kip1): Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells
-
Wolf, G., Reinking, R., Zahner, G., Stahl, R.A., Shankland, S.J., Erk 1,2 phosphorylates p27(Kip1): Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells. Diabetologia 46 (2003), 1090–1099.
-
(2003)
Diabetologia
, vol.46
, pp. 1090-1099
-
-
Wolf, G.1
Reinking, R.2
Zahner, G.3
Stahl, R.A.4
Shankland, S.J.5
-
226
-
-
31644445070
-
p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency
-
Wolf, G., Schanze, A., Stahl, R.A., Shankland, S.J., Amann, K., p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency. Kidney Int 68 (2005), 1583–1589.
-
(2005)
Kidney Int
, vol.68
, pp. 1583-1589
-
-
Wolf, G.1
Schanze, A.2
Stahl, R.A.3
Shankland, S.J.4
Amann, K.5
-
227
-
-
0031596570
-
Glomerular expression of p27Kip1 in diabetic db/db mouse: role of hyperglycemia
-
Wolf, G., Schroeder, R., Thaiss, F., Ziyadeh, F.N., Helmchen, U., Stahl, R.A., Glomerular expression of p27Kip1 in diabetic db/db mouse: role of hyperglycemia. Kidney Int 53 (1998), 869–879.
-
(1998)
Kidney Int
, vol.53
, pp. 869-879
-
-
Wolf, G.1
Schroeder, R.2
Thaiss, F.3
Ziyadeh, F.N.4
Helmchen, U.5
Stahl, R.A.6
-
228
-
-
62149150630
-
PKC-beta1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesangial cells
-
Wu, D., Peng, F., Zhang, B., Ingram, A.J., Kelly, D.J., Gilbert, R.E., Gao, B., Krepinsky, J.C., PKC-beta1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesangial cells. J. Am. Soc. Nephrol. 20 (2009), 554–566.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 554-566
-
-
Wu, D.1
Peng, F.2
Zhang, B.3
Ingram, A.J.4
Kelly, D.J.5
Gilbert, R.E.6
Gao, B.7
Krepinsky, J.C.8
-
229
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger, S., Loewith, R., Hall, M.N., TOR signaling in growth and metabolism. Cell 124 (2006), 471–484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
230
-
-
33644866156
-
Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression
-
Xia, L., Wang, H., Goldberg, H.J., Munk, S., Fantus, I.G., Whiteside, C.I., Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression. Am. J. Physiol. Ren. Physiol. 290 (2006), F345–F356.
-
(2006)
Am. J. Physiol. Ren. Physiol.
, vol.290
, pp. F345-F356
-
-
Xia, L.1
Wang, H.2
Goldberg, H.J.3
Munk, S.4
Fantus, I.G.5
Whiteside, C.I.6
-
231
-
-
84859343649
-
Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes
-
Yamagishi, S., Maeda, S., Matsui, T., Ueda, S., Fukami, K., Okuda, S., Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes. Biochim Biophys. Acta 1820 (2012), 663–671.
-
(2012)
Biochim Biophys. Acta
, vol.1820
, pp. 663-671
-
-
Yamagishi, S.1
Maeda, S.2
Matsui, T.3
Ueda, S.4
Fukami, K.5
Okuda, S.6
-
232
-
-
34447269956
-
Oral administration of AST-120 (Kremezin) is a promising therapeutic strategy for advanced glycation end product (AGE)-related disorders
-
Yamagishi, S., Nakamura, K., Matsui, T., Inoue, H., Takeuchi, M., Oral administration of AST-120 (Kremezin) is a promising therapeutic strategy for advanced glycation end product (AGE)-related disorders. Med Hypotheses 69 (2007), 666–668.
-
(2007)
Med Hypotheses
, vol.69
, pp. 666-668
-
-
Yamagishi, S.1
Nakamura, K.2
Matsui, T.3
Inoue, H.4
Takeuchi, M.5
-
233
-
-
34748880045
-
Rapamycin prevents early steps of the development of diabetic nephropathy in rats
-
Yang, Y., Wang, J., Qin, L., Shou, Z., Zhao, J., Wang, H., Chen, Y., Chen, J., Rapamycin prevents early steps of the development of diabetic nephropathy in rats. Am. J. Nephrol. 27 (2007), 495–502.
-
(2007)
Am. J. Nephrol.
, vol.27
, pp. 495-502
-
-
Yang, Y.1
Wang, J.2
Qin, L.3
Shou, Z.4
Zhao, J.5
Wang, H.6
Chen, Y.7
Chen, J.8
-
234
-
-
74249099637
-
Different expressions of protein kinase C-alpha, beta I and beta II in glomeruli of diabetic nephropathy patients
-
Yao, L., Wang, J., Mao, Y., Zhu, H., Deng, A., Zhu, Z., Different expressions of protein kinase C-alpha, beta I and beta II in glomeruli of diabetic nephropathy patients. J. Huazhong Univ. Sci. Technol. Med Sci. 26 (2006), 651–653.
-
(2006)
J. Huazhong Univ. Sci. Technol. Med Sci.
, vol.26
, pp. 651-653
-
-
Yao, L.1
Wang, J.2
Mao, Y.3
Zhu, H.4
Deng, A.5
Zhu, Z.6
-
235
-
-
84883061672
-
Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling
-
Yong, R., Chen, X.M., Shen, S., Vijayaraj, S., Ma, Q., Pollock, C.A., Saad, S., Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling. PLoS One, 8, 2013, e73428.
-
(2013)
PLoS One
, vol.8
, pp. e73428
-
-
Yong, R.1
Chen, X.M.2
Shen, S.3
Vijayaraj, S.4
Ma, Q.5
Pollock, C.A.6
Saad, S.7
-
236
-
-
33750579753
-
Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction
-
Yoo, K.H., Thornhill, B.A., Forbes, M.S., Coleman, C.M., Marcinko, E.S., Liaw, L., Chevalier, R.L., Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction. Kidney Int 70 (2006), 1735–1741.
-
(2006)
Kidney Int
, vol.70
, pp. 1735-1741
-
-
Yoo, K.H.1
Thornhill, B.A.2
Forbes, M.S.3
Coleman, C.M.4
Marcinko, E.S.5
Liaw, L.6
Chevalier, R.L.7
-
237
-
-
84922394087
-
[Effects of activation of ALDH2 by ethanol on the expression of JNK in kidney of diabetic rats]
-
Yu, Y., Kang, P.F., Li, H.H., Zhang, G.J., Wang, F.F., Ye, H.W., Gao, Q., [Effects of activation of ALDH2 by ethanol on the expression of JNK in kidney of diabetic rats]. Zhongguo ying yong sheng li xue za zhi=Zhongguo yingyong shenglixue zazhi= Chin. J. Appl. Physiol. 30 (2014), 270–273.
-
(2014)
Zhongguo ying yong sheng li xue za zhi=Zhongguo yingyong shenglixue zazhi= Chin. J. Appl. Physiol.
, vol.30
, pp. 270-273
-
-
Yu, Y.1
Kang, P.F.2
Li, H.H.3
Zhang, G.J.4
Wang, F.F.5
Ye, H.W.6
Gao, Q.7
-
238
-
-
1442327757
-
Common variants in glutamine: fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels
-
Zhang, H., Jia, Y., Cooper, J.J., Hale, T., Zhang, Z., Elbein, S.C., Common variants in glutamine: fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. J. Clin. Endocrinol. Metab. 89 (2004), 748–755.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 748-755
-
-
Zhang, H.1
Jia, Y.2
Cooper, J.J.3
Hale, T.4
Zhang, Z.5
Elbein, S.C.6
-
239
-
-
77956650935
-
Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy
-
Zhang, S., Zhang, Y., Wei, X., Zhen, J., Wang, Z., Li, M., Miao, W., Ding, H., Du, P., Zhang, W., He, M., Yi, F., Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy. Biochim Biophys. Acta 1802 (2010), 1078–1086.
-
(2010)
Biochim Biophys. Acta
, vol.1802
, pp. 1078-1086
-
-
Zhang, S.1
Zhang, Y.2
Wei, X.3
Zhen, J.4
Wang, Z.5
Li, M.6
Miao, W.7
Ding, H.8
Du, P.9
Zhang, W.10
He, M.11
Yi, F.12
-
240
-
-
0034522676
-
High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells
-
Zhang, S.L., Tang, S.S., Chen, X., Filep, J.G., Ingelfinger, J.R., Chan, J.S., High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology 141 (2000), 4637–4646.
-
(2000)
Endocrinology
, vol.141
, pp. 4637-4646
-
-
Zhang, S.L.1
Tang, S.S.2
Chen, X.3
Filep, J.G.4
Ingelfinger, J.R.5
Chan, J.S.6
-
241
-
-
84872421262
-
Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress
-
Zheng, J., Inoguchi, T., Sasaki, S., Maeda, Y., McCarty, M.F., Fujii, M., Ikeda, N., Kobayashi, K., Sonoda, N., Takayanagi, R., Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Am. J. Physiol. Regul. Integr. Comp. Physiol. 304 (2013), R110–R120.
-
(2013)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.304
, pp. R110-R120
-
-
Zheng, J.1
Inoguchi, T.2
Sasaki, S.3
Maeda, Y.4
McCarty, M.F.5
Fujii, M.6
Ikeda, N.7
Kobayashi, K.8
Sonoda, N.9
Takayanagi, R.10
-
242
-
-
41649096963
-
Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway
-
Zheng, J.M., Zhu, J.M., Li, L.S., Liu, Z.H., Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway. Br. J. Pharmacol. 153 (2008), 1456–1464.
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 1456-1464
-
-
Zheng, J.M.1
Zhu, J.M.2
Li, L.S.3
Liu, Z.H.4
-
243
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice
-
Ziyadeh, F.N., Hoffman, B.B., Han, D.C., Iglesias-De La Cruz, M.C., Hong, S.W., Isono, M., Chen, S., McGowan, T.A., Sharma, K., Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. Proc. Natl. Acad. Sci. U S A 97 (2000), 8015–8020.
-
(2000)
Proc. Natl. Acad. Sci. U S A
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
Hoffman, B.B.2
Han, D.C.3
Iglesias-De La Cruz, M.C.4
Hong, S.W.5
Isono, M.6
Chen, S.7
McGowan, T.A.8
Sharma, K.9
-
244
-
-
78650510609
-
mTOR: from growth signal integration to cancer, diabetes and ageing
-
Zoncu, R., Efeyan, A., Sabatini, D.M., mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 12 (2011), 21–35.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
245
-
-
84863548620
-
Aldose reductase regulates platelet-derived growth factor-induced proliferation through mediating cell cycle progression in rat mesangial cells
-
Zou, L., Wang, W., Xu, Z., Zhang, N., Jiang, T., Aldose reductase regulates platelet-derived growth factor-induced proliferation through mediating cell cycle progression in rat mesangial cells. Int J. Mol. Med. 30 (2012), 409–416.
-
(2012)
Int J. Mol. Med.
, vol.30
, pp. 409-416
-
-
Zou, L.1
Wang, W.2
Xu, Z.3
Zhang, N.4
Jiang, T.5
|