메뉴 건너뛰기




Volumn 32, Issue 7-8, 2016, Pages 732-739

Beneficial role of vitamin K supplementation on insulin sensitivity, glucose metabolism, and the reduced risk of type 2 diabetes: A review

Author keywords

Anti inflammatory; Glucose tolerance; Insulin sensitivity; Lipid lowering; Reduced risk of T2 D; Vitamin K

Indexed keywords

ADIPOCYTOKINE; C REACTIVE PROTEIN; FARNOQUINONE; INTERLEUKIN 6; MENAQUINONE; OSTEOCALCIN; PHYTOMENADIONE; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; GLUCOSE BLOOD LEVEL; INSULIN; VITAMIN; VITAMIN K GROUP;

EID: 84964662010     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2016.01.011     Document Type: Review
Times cited : (84)

References (63)
  • 1
    • 33749183217 scopus 로고    scopus 로고
    • Micronutrients in health and disease
    • Shenkin A. Micronutrients in health and disease. Postgrad Med J 2006, 82:559-567.
    • (2006) Postgrad Med J , vol.82 , pp. 559-567
    • Shenkin, A.1
  • 2
    • 84934437875 scopus 로고    scopus 로고
    • Dairy nutrients and their effect on inflammatory profile in molecular studies
    • Da Silva M.S., Rudkowska I. Dairy nutrients and their effect on inflammatory profile in molecular studies. Mol Nutr Food Res 2015, 59:1249-1263.
    • (2015) Mol Nutr Food Res , vol.59 , pp. 1249-1263
    • Da Silva, M.S.1    Rudkowska, I.2
  • 3
    • 77956629251 scopus 로고    scopus 로고
    • Role of vitamins and minerals in prevention and management of type 2 diabetes mellitus
    • Martini L.A., Catania A.S., Ferreira S.R. Role of vitamins and minerals in prevention and management of type 2 diabetes mellitus. Nutr Rev 2010, 68:341-354.
    • (2010) Nutr Rev , vol.68 , pp. 341-354
    • Martini, L.A.1    Catania, A.S.2    Ferreira, S.R.3
  • 5
    • 0023192852 scopus 로고
    • Micronutrient status in diabetes mellitus
    • Mooradian A.D., Morley J.E. Micronutrient status in diabetes mellitus. Am J Clin Nutr 1987, 45:877-895.
    • (1987) Am J Clin Nutr , vol.45 , pp. 877-895
    • Mooradian, A.D.1    Morley, J.E.2
  • 6
    • 84938955918 scopus 로고    scopus 로고
    • The effect of vitamin K1 supplementation on sensitivity and insulin resistance via osteocalcin in prediabetic women: a double-blind randomized controlled clinical trial
    • Rasekhi H., Karandish M., Jalali M.T., Mohammad-Shahi M., Zarei M., Saki A., et al. The effect of vitamin K1 supplementation on sensitivity and insulin resistance via osteocalcin in prediabetic women: a double-blind randomized controlled clinical trial. Eur J Clin Nutr 2015, 69:891-895.
    • (2015) Eur J Clin Nutr , vol.69 , pp. 891-895
    • Rasekhi, H.1    Karandish, M.2    Jalali, M.T.3    Mohammad-Shahi, M.4    Zarei, M.5    Saki, A.6
  • 7
    • 47249094150 scopus 로고    scopus 로고
    • Phylloquinone intake, insulin sensitivity, and glycemic status in men and women
    • Yoshida M., Booth S.L., Meigs J.B., Saltzman E., Jacques P.F. Phylloquinone intake, insulin sensitivity, and glycemic status in men and women. Am J Clin Nutr 2008, 88:210-215.
    • (2008) Am J Clin Nutr , vol.88 , pp. 210-215
    • Yoshida, M.1    Booth, S.L.2    Meigs, J.B.3    Saltzman, E.4    Jacques, P.F.5
  • 8
    • 56649121013 scopus 로고    scopus 로고
    • Effect of vitamin K supplementation on insulin resistance in older men and women
    • Yoshida M., Jacques P.F., Meigs J.B., Saltzman E., Shea M.K., Gundberg C., et al. Effect of vitamin K supplementation on insulin resistance in older men and women. Diabetes Care 2008, 31:2092-2096.
    • (2008) Diabetes Care , vol.31 , pp. 2092-2096
    • Yoshida, M.1    Jacques, P.F.2    Meigs, J.B.3    Saltzman, E.4    Shea, M.K.5    Gundberg, C.6
  • 9
    • 78651284020 scopus 로고    scopus 로고
    • Effect of phylloquinone supplementation on glucose homeostasis in humans
    • Kumar R., Binkley N., Vella A. Effect of phylloquinone supplementation on glucose homeostasis in humans. Am J Clin Nutr 2010, 92:1528-1532.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1528-1532
    • Kumar, R.1    Binkley, N.2    Vella, A.3
  • 11
    • 84867790136 scopus 로고    scopus 로고
    • Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease
    • Ibarrola-Jurado N., Salas-Salvado J., Martinez-Gonzalez M.A., Bullo M. Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease. Am J Clin Nutr 2012, 96:1113-1118.
    • (2012) Am J Clin Nutr , vol.96 , pp. 1113-1118
    • Ibarrola-Jurado, N.1    Salas-Salvado, J.2    Martinez-Gonzalez, M.A.3    Bullo, M.4
  • 12
    • 28344440666 scopus 로고    scopus 로고
    • The vitamin K cycle
    • Stafford D.W. The vitamin K cycle. J Thromb Haemost 2005, 3:1873-1878.
    • (2005) J Thromb Haemost , vol.3 , pp. 1873-1878
    • Stafford, D.W.1
  • 13
    • 0031967116 scopus 로고    scopus 로고
    • Dietary intake and adequacy of vitamin K
    • Booth S.L., Suttie J.W. Dietary intake and adequacy of vitamin K. J Nutr 1998, 128:785-788.
    • (1998) J Nutr , vol.128 , pp. 785-788
    • Booth, S.L.1    Suttie, J.W.2
  • 14
    • 67749093218 scopus 로고    scopus 로고
    • Roles for vitamin K beyond coagulation
    • Booth S.L. Roles for vitamin K beyond coagulation. Annu Rev Nutr 2009, 29:89-110.
    • (2009) Annu Rev Nutr , vol.29 , pp. 89-110
    • Booth, S.L.1
  • 15
    • 84866283031 scopus 로고    scopus 로고
    • Vitamin K nutrition, metabolism, and requirements: current concepts and future research
    • Shearer M.J., Fu X., Booth S.L. Vitamin K nutrition, metabolism, and requirements: current concepts and future research. Adv Nutr 2012, 3:182-195.
    • (2012) Adv Nutr , vol.3 , pp. 182-195
    • Shearer, M.J.1    Fu, X.2    Booth, S.L.3
  • 16
    • 0032868403 scopus 로고    scopus 로고
    • Relationship between acute insulin response and vitamin K intake in healthy young male volunteers
    • Sakamoto N., Nishiike T., Iguchi H., Sakamoto K. Relationship between acute insulin response and vitamin K intake in healthy young male volunteers. Diabetes Nutr Metab 1999, 12:37-41.
    • (1999) Diabetes Nutr Metab , vol.12 , pp. 37-41
    • Sakamoto, N.1    Nishiike, T.2    Iguchi, H.3    Sakamoto, K.4
  • 18
    • 77951523054 scopus 로고    scopus 로고
    • Dietary phylloquinone intakes and metabolic syndrome in US young adults
    • Pan Y., Jackson R.T. Dietary phylloquinone intakes and metabolic syndrome in US young adults. J Am Coll Nutr 2009, 28:369-379.
    • (2009) J Am Coll Nutr , vol.28 , pp. 369-379
    • Pan, Y.1    Jackson, R.T.2
  • 19
    • 84860790835 scopus 로고    scopus 로고
    • Vitamin K2 supplementation improves insulin sensitivity via osteocalcin metabolism: a placebo-controlled trial
    • Choi H.J., Yu J., Choi H., An J.H., Kim S.W., Park K.S., et al. Vitamin K2 supplementation improves insulin sensitivity via osteocalcin metabolism: a placebo-controlled trial. Diabetes Care 2011, 34:e147.
    • (2011) Diabetes Care , vol.34 , pp. e147
    • Choi, H.J.1    Yu, J.2    Choi, H.3    An, J.H.4    Kim, S.W.5    Park, K.S.6
  • 21
    • 0028350542 scopus 로고
    • Effect on breast cancer screening response in The Netherlands of inviting women for an additional scientific investigation
    • Peeters P.H., Beckers C.G., Hogervorst J.M., Collette H.J. Effect on breast cancer screening response in The Netherlands of inviting women for an additional scientific investigation. J Epidemiol Community Health 1994, 48:175-177.
    • (1994) J Epidemiol Community Health , vol.48 , pp. 175-177
    • Peeters, P.H.1    Beckers, C.G.2    Hogervorst, J.M.3    Collette, H.J.4
  • 22
    • 33845425585 scopus 로고    scopus 로고
    • Cardiovascular disease and cognitive performance in middle-aged and elderly men
    • Muller M., Grobbee D.E., Aleman A., Bots M., van der Schouw Y.T. Cardiovascular disease and cognitive performance in middle-aged and elderly men. Atherosclerosis 2007, 190:143-149.
    • (2007) Atherosclerosis , vol.190 , pp. 143-149
    • Muller, M.1    Grobbee, D.E.2    Aleman, A.3    Bots, M.4    van der Schouw, Y.T.5
  • 24
    • 54949147219 scopus 로고    scopus 로고
    • Matrix Gla-protein: the calcification inhibitor in need of vitamin K
    • Schurgers L.J., Cranenburg E.C., Vermeer C. Matrix Gla-protein: the calcification inhibitor in need of vitamin K. Thromb Haemost 2008, 100:593-603.
    • (2008) Thromb Haemost , vol.100 , pp. 593-603
    • Schurgers, L.J.1    Cranenburg, E.C.2    Vermeer, C.3
  • 25
    • 84922227387 scopus 로고    scopus 로고
    • Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-kappaB activation and iNOS expression in rat pancreas
    • Varsha M.K., Thiagarajan R., Manikandan R., Dhanasekaran G. Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-kappaB activation and iNOS expression in rat pancreas. Nutrition 2015, 31:214-222.
    • (2015) Nutrition , vol.31 , pp. 214-222
    • Varsha, M.K.1    Thiagarajan, R.2    Manikandan, R.3    Dhanasekaran, G.4
  • 26
    • 84907880606 scopus 로고    scopus 로고
    • Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis
    • Sai Varsha M.K., Raman T., Manikandan R. Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis. Exp Eye Res 2014, 128:73-82.
    • (2014) Exp Eye Res , vol.128 , pp. 73-82
    • Sai Varsha, M.K.1    Raman, T.2    Manikandan, R.3
  • 27
    • 79954451422 scopus 로고    scopus 로고
    • Vitamin K(2) prevents hyperglycemia and cancellous osteopenia in rats with streptozotocin-induced type 1 diabetes
    • Iwamoto J., Seki A., Sato Y., Matsumoto H., Takeda T., Yeh J.K. Vitamin K(2) prevents hyperglycemia and cancellous osteopenia in rats with streptozotocin-induced type 1 diabetes. Calcif Tissue Int 2011, 88:162-168.
    • (2011) Calcif Tissue Int , vol.88 , pp. 162-168
    • Iwamoto, J.1    Seki, A.2    Sato, Y.3    Matsumoto, H.4    Takeda, T.5    Yeh, J.K.6
  • 28
    • 84861566249 scopus 로고    scopus 로고
    • Streptozotocin-induced cytotoxicity, oxidative stress, and mitochondrial dysfunction in human hepatoma HepG2 cells
    • Raza H., John A. Streptozotocin-induced cytotoxicity, oxidative stress, and mitochondrial dysfunction in human hepatoma HepG2 cells. Int J Mol Sci 2012, 13:5751-5767.
    • (2012) Int J Mol Sci , vol.13 , pp. 5751-5767
    • Raza, H.1    John, A.2
  • 29
    • 84968810764 scopus 로고    scopus 로고
    • Protective role of vitamin K against impaired glucose homeostasis in ovariectomized exercised and nonexercised rats
    • Khalil A., Youssef G.A., Al-Saeed H.F. Protective role of vitamin K against impaired glucose homeostasis in ovariectomized exercised and nonexercised rats. Nat Sci 2014, 12:1-9.
    • (2014) Nat Sci , vol.12 , pp. 1-9
    • Khalil, A.1    Youssef, G.A.2    Al-Saeed, H.F.3
  • 30
    • 84871065191 scopus 로고    scopus 로고
    • The role of osteocalcin in human glucose metabolism: marker or mediator?
    • Booth S.L., Centi A., Smith S.R., Gundberg C. The role of osteocalcin in human glucose metabolism: marker or mediator?. Nat Rev Endocrinol 2013, 9:43-55.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 43-55
    • Booth, S.L.1    Centi, A.2    Smith, S.R.3    Gundberg, C.4
  • 31
    • 34547690686 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism by the skeleton
    • Lee N.K., Sowa H., Hinoi E., Ferron M., Ahn J.D., Confavreux C., et al. Endocrine regulation of energy metabolism by the skeleton. Cell 2007, 130:456-469.
    • (2007) Cell , vol.130 , pp. 456-469
    • Lee, N.K.1    Sowa, H.2    Hinoi, E.3    Ferron, M.4    Ahn, J.D.5    Confavreux, C.6
  • 32
    • 42449096306 scopus 로고    scopus 로고
    • Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
    • Ferron M., Hinoi E., Karsenty G., Ducy P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci U S A 2008, 105:5266-5270.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5266-5270
    • Ferron, M.1    Hinoi, E.2    Karsenty, G.3    Ducy, P.4
  • 34
    • 77953921007 scopus 로고    scopus 로고
    • Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome
    • Saleem U., Mosley T.H., Kullo I.J. Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome. Arterioscler Thromb Vasc Biol 2010, 30:1474-1478.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1474-1478
    • Saleem, U.1    Mosley, T.H.2    Kullo, I.J.3
  • 36
    • 84862062726 scopus 로고    scopus 로고
    • Age group and sex do not influence responses of vitamin K biomarkers to changes in dietary vitamin K
    • Truong J.T., Fu X., Saltzman E., Al Rajabi A., Dallal G.E., Gundberg C.M., et al. Age group and sex do not influence responses of vitamin K biomarkers to changes in dietary vitamin K. J Nutr 2012, 142:936-941.
    • (2012) J Nutr , vol.142 , pp. 936-941
    • Truong, J.T.1    Fu, X.2    Saltzman, E.3    Al Rajabi, A.4    Dallal, G.E.5    Gundberg, C.M.6
  • 39
    • 0031917773 scopus 로고    scopus 로고
    • Diurnal variation in total and undercarboxylated osteocalcin: influence of increased dietary phylloquinone
    • Sokoll L.J., Booth S.L., Davidson K.W., Dallal G.E., Sadowski J.A. Diurnal variation in total and undercarboxylated osteocalcin: influence of increased dietary phylloquinone. Calcif Tissue Int 1998, 62:447-452.
    • (1998) Calcif Tissue Int , vol.62 , pp. 447-452
    • Sokoll, L.J.1    Booth, S.L.2    Davidson, K.W.3    Dallal, G.E.4    Sadowski, J.A.5
  • 40
    • 84855987634 scopus 로고    scopus 로고
    • The contribution of bone to whole-organism physiology
    • Karsenty G., Ferron M. The contribution of bone to whole-organism physiology. Nature 2012, 481:314-320.
    • (2012) Nature , vol.481 , pp. 314-320
    • Karsenty, G.1    Ferron, M.2
  • 42
    • 0031792815 scopus 로고    scopus 로고
    • Vitamin K status and bone health: an analysis of methods for determination of undercarboxylated osteocalcin
    • Gundberg C.M., Nieman S.D., Abrams S., Rosen H. Vitamin K status and bone health: an analysis of methods for determination of undercarboxylated osteocalcin. J Clin Endocrinol Metab 1998, 83:3258-3266.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3258-3266
    • Gundberg, C.M.1    Nieman, S.D.2    Abrams, S.3    Rosen, H.4
  • 44
    • 33644839811 scopus 로고    scopus 로고
    • Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes
    • Zhao Y.F., Feng D.D., Chen C. Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes. Int J Biochem Cell Biol 2006, 38:804-819.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 804-819
    • Zhao, Y.F.1    Feng, D.D.2    Chen, C.3
  • 45
    • 84874406712 scopus 로고    scopus 로고
    • The role of adipokines in beta-cell failure of type 2 diabetes
    • Dunmore S.J., Brown J.E. The role of adipokines in beta-cell failure of type 2 diabetes. J Endocrinol 2013, 216:T37-T45.
    • (2013) J Endocrinol , vol.216 , pp. T37-T45
    • Dunmore, S.J.1    Brown, J.E.2
  • 46
    • 84871967263 scopus 로고    scopus 로고
    • Association between dietary phylloquinone intake and peripheral metabolic risk markers related to insulin resistance and diabetes in elderly subjects at high cardiovascular risk
    • Juanola-Falgarona M., Salas-Salvado J., Estruch R., Portillo M.P., Casas R., Miranda J., et al. Association between dietary phylloquinone intake and peripheral metabolic risk markers related to insulin resistance and diabetes in elderly subjects at high cardiovascular risk. Cardiovasc Diabetol 2013, 12:7.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 7
    • Juanola-Falgarona, M.1    Salas-Salvado, J.2    Estruch, R.3    Portillo, M.P.4    Casas, R.5    Miranda, J.6
  • 47
    • 84883234646 scopus 로고    scopus 로고
    • Adiponectin, driver or passenger on the road to insulin sensitivity?
    • Ye R., Scherer P.E. Adiponectin, driver or passenger on the road to insulin sensitivity?. Mol Metab 2013, 2:133-141.
    • (2013) Mol Metab , vol.2 , pp. 133-141
    • Ye, R.1    Scherer, P.E.2
  • 48
    • 84927775533 scopus 로고    scopus 로고
    • Phylloquinone supplementation improves glycemic status independent of the effects of adiponectin levels in premonopause women with prediabetes: a double-blind randomized controlled clinical trial
    • Rasekhi H., Karandish M., Jalali M.T., Mohammadshahi M., Zarei M., Saki A., et al. Phylloquinone supplementation improves glycemic status independent of the effects of adiponectin levels in premonopause women with prediabetes: a double-blind randomized controlled clinical trial. J Diabetes Metab Disord 2015, 14:1.
    • (2015) J Diabetes Metab Disord , vol.14 , pp. 1
    • Rasekhi, H.1    Karandish, M.2    Jalali, M.T.3    Mohammadshahi, M.4    Zarei, M.5    Saki, A.6
  • 49
    • 84866139256 scopus 로고    scopus 로고
    • Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight
    • Knapen M.H., Schurgers L.J., Shearer M.J., Newman P., Theuwissen E., Vermeer C. Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight. Br J Nutr 2012, 108:1017-1024.
    • (2012) Br J Nutr , vol.108 , pp. 1017-1024
    • Knapen, M.H.1    Schurgers, L.J.2    Shearer, M.J.3    Newman, P.4    Theuwissen, E.5    Vermeer, C.6
  • 50
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996, 271:665-668.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 51
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 52
    • 77958151829 scopus 로고    scopus 로고
    • Vitamin K suppresses the lipopolysaccharide-induced expression of inflammatory cytokines in cultured macrophage-like cells via the inhibition of the activation of nuclear factor kappaB through the repression of IKKalpha/beta phosphorylation
    • Ohsaki Y., Shirakawa H., Miura A., Giriwono P.E., Sato S., Ohashi A., et al. Vitamin K suppresses the lipopolysaccharide-induced expression of inflammatory cytokines in cultured macrophage-like cells via the inhibition of the activation of nuclear factor kappaB through the repression of IKKalpha/beta phosphorylation. J Nutr Biochem 2010, 21:1120-1126.
    • (2010) J Nutr Biochem , vol.21 , pp. 1120-1126
    • Ohsaki, Y.1    Shirakawa, H.2    Miura, A.3    Giriwono, P.E.4    Sato, S.5    Ohashi, A.6
  • 53
    • 0028997159 scopus 로고
    • Interleukin 6 production by lipopolysaccharide-stimulated human fibroblasts is potently inhibited by naphthoquinone (vitamin K) compounds
    • Reddi K., Henderson B., Meghji S., Wilson M., Poole S., Hopper C., et al. Interleukin 6 production by lipopolysaccharide-stimulated human fibroblasts is potently inhibited by naphthoquinone (vitamin K) compounds. Cytokine 1995, 7:287-290.
    • (1995) Cytokine , vol.7 , pp. 287-290
    • Reddi, K.1    Henderson, B.2    Meghji, S.3    Wilson, M.4    Poole, S.5    Hopper, C.6
  • 55
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen K.E., Hotamisligil G.S. Inflammation, stress, and diabetes. J Clin Invest 2005, 115:1111-1119.
    • (2005) J Clin Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 57
    • 0030609023 scopus 로고    scopus 로고
    • Effects of vitamin K2 (menatetrenone) on atherosclerosis and blood coagulation in hypercholesterolemic rabbits
    • Kawashima H., Nakajima Y., Matubara Y., Nakanowatari J., Fukuta T., Mizuno S., et al. Effects of vitamin K2 (menatetrenone) on atherosclerosis and blood coagulation in hypercholesterolemic rabbits. Jpn J Pharmacol 1997, 75:135-143.
    • (1997) Jpn J Pharmacol , vol.75 , pp. 135-143
    • Kawashima, H.1    Nakajima, Y.2    Matubara, Y.3    Nakanowatari, J.4    Fukuta, T.5    Mizuno, S.6
  • 58
    • 79954585466 scopus 로고    scopus 로고
    • Effects of long-term vitamin K(1) (phylloquinone) or vitamin K supplementation on body composition and serum parameters in rats
    • Sogabe N., Maruyama R., Baba O., Hosoi T., Goseki-Sone M. Effects of long-term vitamin K(1) (phylloquinone) or vitamin K supplementation on body composition and serum parameters in rats. Bone 2011, 48:1036-1042.
    • (2011) Bone , vol.48 , pp. 1036-1042
    • Sogabe, N.1    Maruyama, R.2    Baba, O.3    Hosoi, T.4    Goseki-Sone, M.5
  • 59
    • 0032492256 scopus 로고    scopus 로고
    • Vitamin K2 and serum cholesterol in patients on continuous ambulatory peritoneal dialysis
    • Nagasawa Y., Fujii M., Kajimoto Y., Imai E., Hori M. Vitamin K2 and serum cholesterol in patients on continuous ambulatory peritoneal dialysis. Lancet 1998, 351:724.
    • (1998) Lancet , vol.351 , pp. 724
    • Nagasawa, Y.1    Fujii, M.2    Kajimoto, Y.3    Imai, E.4    Hori, M.5
  • 60
    • 84926670098 scopus 로고    scopus 로고
    • Effects of phylloquinone supplementation on lipid profile in women with rheumatoid arthritis: a double blind placebo controlled study
    • Kolahi S., Pourghassem Gargari B., Mesgari Abbasi M., Asghari Jafarabadi M., Ghamarzad Shishavan N. Effects of phylloquinone supplementation on lipid profile in women with rheumatoid arthritis: a double blind placebo controlled study. Nutr Res Pract 2015, 9:186-191.
    • (2015) Nutr Res Pract , vol.9 , pp. 186-191
    • Kolahi, S.1    Pourghassem Gargari, B.2    Mesgari Abbasi, M.3    Asghari Jafarabadi, M.4    Ghamarzad Shishavan, N.5
  • 62
    • 41249102720 scopus 로고    scopus 로고
    • Determinants of vitamin K status in humans
    • Booth S.L., Al Rajabi A. Determinants of vitamin K status in humans. Vitam Horm 2008, 78:1-22.
    • (2008) Vitam Horm , vol.78 , pp. 1-22
    • Booth, S.L.1    Al Rajabi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.