-
1
-
-
0016713780
-
Incidence of chronic renal insufficiency. A study of the incidence and pattern of renal insufficiency in adults during 1966-1971 in Gothenburg
-
Ahlmn, J. Incidence of chronic renal insufficiency. A study of the incidence and pattern of renal insufficiency in adults during 1966-1971 in Gothenburg. Acta Med. Scand. Suppl. 582, 1-50 (1975
-
(1975)
Acta Med. Scand
, vol.582
, Issue.SUPPL.
, pp. 1-50
-
-
Ahlmn, J.1
-
2
-
-
0017355716
-
Chronic progressive renal disease: Rate of change of serum creatinine concentration
-
Rutherford, W. E., Blondin, J., Miller, J. P., Greenwalt, A. S. & Vavra, J. D. Chronic progressive renal disease: Rate of change of serum creatinine concentration. Kidney Int. 11, 62-70 (1977
-
(1977)
Kidney Int.
, vol.11
, pp. 62-70
-
-
Rutherford, W.E.1
Blondin, J.2
Miller, J.P.3
Greenwalt, A.S.4
Vavra, J.D.5
-
3
-
-
0017818135
-
Progression of renal insufficiency in pediatric patients: Estimation from serum creatinine
-
Leumann, E. P. Progression of renal insufficiency in pediatric patients: Estimation from serum creatinine. Helv. Paediatr. Acta 33, 25-35 (1978
-
(1978)
Helv. Paediatr. Acta
, vol.33
, pp. 25-35
-
-
Leumann, E.P.1
-
4
-
-
84877952308
-
A simple tool to predict end-stage renal disease within 1 year in elderly adults with advanced chronic kidney disease
-
Drawz, P. E., Goswami, P., Azem, R., Babineau, D. C. & Rahman, M. A simple tool to predict end-stage renal disease within 1 year in elderly adults with advanced chronic kidney disease. J. Am. Geriatr. Soc. 61, 762-768 (2013
-
(2013)
J. Am. Geriatr. Soc.
, vol.61
, pp. 762-768
-
-
Drawz, P.E.1
Goswami, P.2
Azem, R.3
Babineau, D.C.4
Rahman, M.5
-
5
-
-
84875515151
-
Early recognition of CKD can delay progression
-
McLaughlin, M. J. & Courtney, A. E. Early recognition of CKD can delay progression. Practitioner 257, 13-17 (2013
-
(2013)
Practitioner
, vol.257
, pp. 13-17
-
-
McLaughlin, M.J.1
Courtney, A.E.2
-
6
-
-
84875133121
-
Advances in CKD detection and determination of prognosis: Executive summary of the National Kidney Foundation-Kidney Early Evaluation Program (KEEP) 2012 annual data report
-
Whaley-Connell, A. T., Tamura, M. K., Jurkovitz, C. T., Kosiborod, M. & McCullough, P. A. Advances in CKD detection and determination of prognosis: Executive summary of the National Kidney Foundation-Kidney Early Evaluation Program (KEEP) 2012 annual data report. Am. J. Kidney Dis. 61, S1-S3 (2013
-
(2013)
Am. J. Kidney Dis.
, vol.61
-
-
Whaley-Connell, A.T.1
Tamura, M.K.2
Jurkovitz, C.T.3
Kosiborod, M.4
McCullough, P.A.5
-
7
-
-
0032499911
-
Reversal of lesions of diabetic nephropathy after pancreas transplantation
-
Fioretto, P., Steffes, M. W., Sutherland, D. E., Goetz, F. C. & Mauer, M. Reversal of lesions of diabetic nephropathy after pancreas transplantation, N. Engl. J. Med. 339, 69-75 (1998
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 69-75
-
-
Fioretto, P.1
Steffes, M.W.2
Sutherland, D.E.3
Goetz, F.C.4
Mauer, M.5
-
8
-
-
33644503909
-
Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
-
Fioretto, P., Sutherland, D. E., Najafian, B. & Mauer, M. Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients. Kidney Int. 69, 907-912 (2006
-
(2006)
Kidney Int.
, vol.69
, pp. 907-912
-
-
Fioretto, P.1
Sutherland, D.E.2
Najafian, B.3
Mauer, M.4
-
9
-
-
70949103630
-
Regression of diabetic complications by islet transplantation in the rat
-
Remuzzi, A. et al. Regression of diabetic complications by islet transplantation in the rat. Diabetologia 52, 2653-2661 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 2653-2661
-
-
Remuzzi, A.1
-
10
-
-
0014421532
-
Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
-
Risdon, R. A., Sloper, J. C. & De Wardener, H. E. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 2, 363-366 (1968
-
(1968)
Lancet
, vol.2
, pp. 363-366
-
-
Risdon, R.A.1
Sloper, J.C.2
De Wardener, H.E.3
-
11
-
-
0017783270
-
Correlation between relative interstitial volume of the renal cortex and serum creatinine concentration in minimal changes with nephrotic syndrome and in focal sclerosing glomerulonephritis
-
Bohle, A., Glomb, D., Grund, K. E. & Mackensen, S. Correlation between relative interstitial volume of the renal cortex and serum creatinine concentration in minimal changes with nephrotic syndrome and in focal sclerosing glomerulonephritis. Virchows Arch. A Pathol. Anat. Histol. 376, 221-232 (1977
-
(1977)
Virchows Arch. A Pathol. Anat. Histol.
, vol.376
, pp. 221-232
-
-
Bohle, A.1
Glomb, D.2
Grund, K.E.3
Mackensen, S.4
-
12
-
-
84873344021
-
Cellular mechanisms of tissue fibrosis Common and organ-specific mechanisms associated with tissue fibrosis
-
Zeisberg, M. & Kalluri, R. Cellular mechanisms of tissue fibrosis. Common and organ-specific mechanisms associated with tissue fibrosis. Am. J. Physiol. Cell Physiol. 304, C216-C225 (2013
-
(2013)
Am. J. Physiol. Cell Physiol
, vol.304
-
-
Zeisberg, M.1
Kalluri, R.2
-
13
-
-
84863702343
-
Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
-
Wynn, T. A. & Ramalingam, T. R. Mechanisms of fibrosis: Therapeutic translation for fibrotic disease. Nat. Med. 18, 1028-1040 (2012
-
(2012)
Nat. Med.
, vol.18
, pp. 1028-1040
-
-
Wynn, T.A.1
Ramalingam, T.R.2
-
14
-
-
78149298226
-
Mechanisms of tubulointerstitial fibrosis
-
Zeisberg, M. & Neilson, E. G. Mechanisms of tubulointerstitial fibrosis. J. Am. Soc. Nephrol. 21, 1819-1834 (2010
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 1819-1834
-
-
Zeisberg, M.1
Neilson, E.G.2
-
15
-
-
39349099274
-
Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells
-
Aydin, S. et al. Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells. Am. J. Physiol. Cell Physiol. 294, C543-C554 (2008
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.294
-
-
Aydin, S.1
-
16
-
-
0030419494
-
Molecular insights into renal interstitial fibrosis
-
Eddy, A. A. Molecular insights into renal interstitial fibrosis. J. Am. Soc. Nephrol. 7, 2495-2508 (1996
-
(1996)
J. Am. Soc. Nephrol.
, vol.7
, pp. 2495-2508
-
-
Eddy, A.A.1
-
17
-
-
0035086732
-
TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy
-
Kim, H. et al. TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy. J. Am. Soc. Nephrol. 12, 736-748 (2001
-
(2001)
J. Am. Soc. Nephrol.
, vol.12
, pp. 736-748
-
-
Kim, H.1
-
18
-
-
0036854980
-
Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
-
Yang, J. et al. Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J. Clin. Invest. 110, 1525-1538 (2002
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1525-1538
-
-
Yang, J.1
-
19
-
-
33646266237
-
Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease
-
Zeisberg, M. et al. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease, PLoS Med. 3, e100 (2006
-
(2006)
PLoS Med.
, vol.3
-
-
Zeisberg, M.1
-
20
-
-
0038717407
-
BMP-7 counteracts TGF-1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg, M. et al. BMP-7 counteracts TGF-1-induced epithelial-to- mesenchymal transition and reverses chronic renal injury. Nat. Med. 9, 964-968 (2003
-
(2003)
Nat. Med.
, vol.9
, pp. 964-968
-
-
Zeisberg, M.1
-
21
-
-
0242582117
-
Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
-
Zeisberg, M. et al. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am. J. Physiol. Renal Physiol. 285, F1060-F1067 (2003
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.285
-
-
Zeisberg, M.1
-
22
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale, J. P. et al. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J. Clin. Invest. 102, 538-549 (1998
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
-
23
-
-
1542374741
-
Reversal of liver fibrosis and cirrhosis-an emerging reality
-
Fallowfield, J. A. & Iredale, J. P. Reversal of liver fibrosis and cirrhosis-an emerging reality. Scott. Med. J. 49, 3-6 (2004
-
(2004)
Scott. Med. J.
, vol.49
, pp. 3-6
-
-
Fallowfield, J.A.1
Iredale, J.P.2
-
24
-
-
0034808233
-
Matrix as a modulator of hepatic fibrogenesis Semin
-
Schuppan, D., Ruehl, M., Somasundaram, R. & Hahn, E. G. Matrix as a modulator of hepatic fibrogenesis, Semin. Liver Dis. 21, 351-372 (2001
-
(2001)
Liver Dis.
, vol.21
, pp. 351-372
-
-
Schuppan, D.1
Ruehl, M.2
Somasundaram, R.3
Hahn, E.G.4
-
25
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
Barry-Hamilton, V. et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat. Med. 16, 1009-1017 (2010
-
(2010)
Nat. Med.
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
-
26
-
-
0034323610
-
Role of fibroblast activation in inducing interstitial fibrosis
-
Zeisberg, M., Strutz, F. & Mller, G. A. Role of fibroblast activation in inducing interstitial fibrosis. J. Nephrol. 13 (Suppl. 3), S111-S120 (2000
-
(2000)
J. Nephrol.
, vol.13
, Issue.SUPPL. 3
-
-
Zeisberg, M.1
Strutz, F.2
Mller, G.A.3
-
27
-
-
32944464939
-
Toward a unified theory of renal progression
-
Harris, R. C. & Neilson, E. G. Toward a unified theory of renal progression. Annu. Rev. Med. 57, 365-380 (2006
-
(2006)
Annu. Rev. Med.
, vol.57
, pp. 365-380
-
-
Harris, R.C.1
Neilson, E.G.2
-
28
-
-
0025816170
-
Characterization of human renal fibroblasts in health and disease: II.In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis
-
Rodemann, H. P. & Mller, G. A. Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis. Am. J. Kidney Dis. 17, 684-686 (1991
-
(1991)
Am. J. Kidney Dis.
, vol.17
, pp. 684-686
-
-
Rodemann, H.P.1
Mller, G.A.2
-
29
-
-
77952116121
-
Methylation determines fibroblast activation and fibrogenesis in the kidney
-
Bechtel, W. et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat. Med. 16, 544-550 (2010
-
(2010)
Nat. Med.
, vol.16
, pp. 544-550
-
-
Bechtel, W.1
-
30
-
-
84882289111
-
Origin and function of myofibroblasts in kidney fibrosis
-
LeBleu, V. S. et al. Origin and function of myofibroblasts in kidney fibrosis. Nat. Med. 19, 1047-1053 (2013
-
(2013)
Nat. Med.
, vol.19
, pp. 1047-1053
-
-
Lebleu, V.S.1
-
31
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
Iwano, M. et al. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J. Clin. Invest. 110, 341-350 (2002
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 341-350
-
-
Iwano, M.1
-
32
-
-
73949096744
-
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
-
Humphreys, B. D. et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am. J. Pathol. 176, 85-97 (2010
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 85-97
-
-
Humphreys, B.D.1
-
33
-
-
55249103431
-
Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition
-
Zeisberg, E. M., Potenta, S. E., Sugimoto, H., Zeisberg, M. & Kalluri, R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J. Am. Soc. Nephrol. 19, 2282-2287 (2008
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2282-2287
-
-
Zeisberg, E.M.1
Potenta, S.E.2
Sugimoto, H.3
Zeisberg, M.4
Kalluri, R.5
-
34
-
-
0022471924
-
Transforming growth factor type : Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
-
USA
-
Roberts, A. B. et al. Transforming growth factor type : Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl Acad. Sci. USA 83, 4167-4171 (1986
-
(1986)
Proc. Natl Acad. Sci.
, vol.83
, pp. 4167-4171
-
-
Roberts, A.B.1
-
35
-
-
80053091084
-
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis
-
Richeldi, L. et al. Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N. Engl. J. Med. 365, 1079-1087 (2011
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1079-1087
-
-
Richeldi, L.1
-
36
-
-
0029816069
-
Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
-
Frazier, K., Williams, S., Kothapalli, D., Klapper, H. & Grotendorst, G. R. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J. Invest. Dermatol. 107, 404-411 (1996
-
(1996)
J. Invest. Dermatol.
, vol.107
, pp. 404-411
-
-
Frazier, K.1
Williams, S.2
Kothapalli, D.3
Klapper, H.4
Grotendorst, G.R.5
-
37
-
-
0029996247
-
Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders
-
Igarashi, A. et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J. Invest. Dermatol. 106, 729-733 (1996
-
(1996)
J. Invest. Dermatol.
, vol.106
, pp. 729-733
-
-
Igarashi, A.1
-
38
-
-
0034981126
-
Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts
-
Iwano, M. et al. Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts. Mol. Ther. 3, 149-159 (2001
-
(2001)
Mol. Ther.
, vol.3
, pp. 149-159
-
-
Iwano, M.1
-
39
-
-
84863984682
-
Tubulointerstitial injury and the progression of chronic kidney disease
-
Hodgkins, K. S. & Schnaper, H. W. Tubulointerstitial injury and the progression of chronic kidney disease. Pediatr. Nephrol. 27, 901-909 (2012
-
(2012)
Pediatr. Nephrol.
, vol.27
, pp. 901-909
-
-
Hodgkins, K.S.1
Schnaper, H.W.2
-
40
-
-
1142275261
-
Mechanisms of tubulointerstitial injury in the kidney: Final common pathways to end-stage renal failure
-
Nangaku, M. Mechanisms of tubulointerstitial injury in the kidney: Final common pathways to end-stage renal failure. Intern. Med. 43, 9-17 (2004
-
(2004)
Intern. Med.
, vol.43
, pp. 9-17
-
-
Nangaku, M.1
-
41
-
-
67650996754
-
Biomarkers for epithelial-mesenchymal transitions
-
Zeisberg, M. & Neilson, E. G. Biomarkers for epithelial-mesenchymal transitions. J. Clin. Invest. 119, 1429-1437 (2009
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
-
42
-
-
84861726854
-
-
ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01791855 (2013
-
(2013)
42 US National Library of Medicine
-
-
-
43
-
-
72949123737
-
Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis
-
Witek, R. P. et al. Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis. Hepatology 50, 1421-1430 (2009
-
(2009)
Hepatology
, vol.50
, pp. 1421-1430
-
-
Witek, R.P.1
-
44
-
-
77952174830
-
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
-
Yang, L., Besschetnova, T. Y., Brooks, C. R., Shah, J. V. & Bonventre, J. V. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat. Med. 16, 535-543 (2010
-
(2010)
Nat. Med.
, vol.16
, pp. 535-543
-
-
Yang, L.1
Besschetnova, T.Y.2
Brooks, C.R.3
Shah, J.V.4
Bonventre, J.V.5
-
45
-
-
13244251415
-
Isolation of renal progenitor cells from adult human kidney
-
Bussolati, B. et al. Isolation of renal progenitor cells from adult human kidney. Am. J. Pathol. 166, 545-555 (2005
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 545-555
-
-
Bussolati, B.1
-
46
-
-
0345530117
-
Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney
-
Maeshima, A., Yamashita, S. & Nojima, Y. Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. J. Am. Soc. Nephrol. 14, 3138-3146 (2003
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 3138-3146
-
-
Maeshima, A.1
Yamashita, S.2
Nojima, Y.3
-
47
-
-
84875037125
-
Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration
-
Smeets, B. et al. Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration. J. Pathol. 229, 645-659 (2013
-
(2013)
J. Pathol.
, vol.229
, pp. 645-659
-
-
Smeets, B.1
-
48
-
-
0036191166
-
Role of the microvascular endothelium in progressive renal disease
-
Kang, D. H. et al. Role of the microvascular endothelium in progressive renal disease. J. Am. Soc. Nephrol. 13, 806-816 (2002
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 806-816
-
-
Kang, D.H.1
-
49
-
-
2542488351
-
Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis
-
Matsumoto, M. et al. Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis. J. Am. Soc. Nephrol. 15, 1574-1581 (2004
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1574-1581
-
-
Matsumoto, M.1
-
50
-
-
42449114928
-
Endothelial dysfunction in CKD: A new player in town
-
Zoccali, C. Endothelial dysfunction in CKD: A new player in town Nephrol. Dial. Transplant. 23, 783-785 (2008
-
(2008)
Nephrol. Dial. Transplant.
, vol.23
, pp. 783-785
-
-
Zoccali, C.1
-
51
-
-
84856171497
-
Microvascular disease precedes the decline in renal function in the streptozotocin-induced diabetic rat
-
Maric-Bilkan, C., Flynn, E. R. & Chade, A. R. Microvascular disease precedes the decline in renal function in the streptozotocin-induced diabetic rat. Am. J. Physiol. Renal Physiol. 302, F308-F315 (2012
-
(2012)
Am. J. Physiol. Renal Physiol.
, vol.302
-
-
Maric-Bilkan, C.1
Flynn, E.R.2
Chade, A.R.3
-
52
-
-
0141997225
-
Beneficial effects of antioxidant vitamins on the stenotic kidney
-
Chade, A. R. et al. Beneficial effects of antioxidant vitamins on the stenotic kidney. Hypertension 42, 605-612 (2003
-
(2003)
Hypertension
, vol.42
, pp. 605-612
-
-
Chade, A.R.1
-
53
-
-
0034884995
-
Proliferation and remodeling of the peritubular microcirculation after nephron reduction: Association with the progression of renal lesions
-
Pillebout, E. et al. Proliferation and remodeling of the peritubular microcirculation after nephron reduction: Association with the progression of renal lesions. Am. J. Pathol. 159, 547-560 (2001
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 547-560
-
-
Pillebout, E.1
-
54
-
-
0036287669
-
Peritubular capillary regression during the progression of experimental obstructive nephropathy
-
Ohashi, R. et al. Peritubular capillary regression during the progression of experimental obstructive nephropathy. J. Am. Soc. Nephrol. 13, 1795-1805 (2002
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 1795-1805
-
-
Ohashi, R.1
-
55
-
-
84881113183
-
Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury
-
Clements, M. E., Chaber, C. J., Ledbetter, S. R. & Zuk, A. Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury. PLoS ONE 8, e70464 (2013
-
(2013)
PLoS ONE
, vol.8
-
-
Clements, M.E.1
Chaber, C.J.2
Ledbetter, S.R.3
Zuk, A.4
-
56
-
-
0025120886
-
Characterization of high endothelial-like properties of peritubular capillary endothelium during acute renal allograft rejection
-
Renkonen, R., Turunen, J. P., Rapola, J. & Hyry, P. Characterization of high endothelial-like properties of peritubular capillary endothelium during acute renal allograft rejection. Am. J. Pathol. 137, 643-651 (1990
-
(1990)
Am. J. Pathol.
, vol.137
, pp. 643-651
-
-
Renkonen, R.1
Turunen, J.P.2
Rapola, J.3
Hyry, P.4
-
57
-
-
84861151993
-
Reversal of renal dysfunction by targeted administration of VEGF into the stenotic kidney: A novel potential therapeutic approach
-
Chade, A. R. & Kelsen, S. Reversal of renal dysfunction by targeted administration of VEGF into the stenotic kidney: A novel potential therapeutic approach. Am. J. Physiol. Renal Physiol. 302, F1342-F1350 (2012
-
(2012)
Am. J. Physiol. Renal Physiol.
, vol.302
-
-
Chade, A.R.1
Kelsen, S.2
-
58
-
-
80051785427
-
Thrombospondin-1 short hairpin RNA suppresses tubulointerstitial fibrosis in the kidney of ureteral obstruction by ameliorating peritubular capillary injury
-
Sun, D. et al. Thrombospondin-1 short hairpin RNA suppresses tubulointerstitial fibrosis in the kidney of ureteral obstruction by ameliorating peritubular capillary injury. Kidney Blood Press. Res. 35, 35-47 (2012
-
(2012)
Kidney Blood Press. Res.
, vol.35
, pp. 35-47
-
-
Sun, D.1
-
59
-
-
3042739353
-
Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy
-
Yamamoto, Y. et al. Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy. Diabetes 53, 1831-1840 (2004
-
(2004)
Diabetes
, vol.53
, pp. 1831-1840
-
-
Yamamoto, Y.1
-
60
-
-
25844484666
-
Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model
-
Ichinose, K. et al. Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model. Diabetes 54, 2891-2903 (2005
-
(2005)
Diabetes
, vol.54
, pp. 2891-2903
-
-
Ichinose, K.1
-
61
-
-
79954555220
-
Renovascular disease, microcirculation, and the progression of renal injury: Role of angiogenesis
-
Chade, A. R. Renovascular disease, microcirculation, and the progression of renal injury: Role of angiogenesis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R783-R790 (2011
-
(2011)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.300
-
-
Chade, A.R.1
-
62
-
-
79954582442
-
Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD
-
Pergola, P. E. et al. Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD. Am. J. Nephrol. 33, 469-476 (2011
-
(2011)
Am. J. Nephrol.
, vol.33
, pp. 469-476
-
-
Pergola, P.E.1
-
63
-
-
0035814655
-
Endothelial cell chimerism after renal transplantation and vascular rejection
-
Lagaaij, E. L. et al. Endothelial cell chimerism after renal transplantation and vascular rejection. Lancet 357, 33-37 (2001
-
(2001)
Lancet
, vol.357
, pp. 33-37
-
-
Lagaaij, E.L.1
-
64
-
-
0035849940
-
Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection
-
Grimm, P. C. et al. Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection. N. Engl. J. Med. 345, 93-97 (2001
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 93-97
-
-
Grimm, P.C.1
-
65
-
-
84857604290
-
Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use
-
Fadini, G. P., Losordo, D. & Dimmeler, S. Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use. Circ. Res. 110, 624-637 (2012
-
(2012)
Circ. Res.
, vol.110
, pp. 624-637
-
-
Fadini, G.P.1
Losordo, D.2
Dimmeler, S.3
-
66
-
-
84886794929
-
The immune system and kidney disease: Basic concepts and clinical implications
-
Kurts, C., Panzer, U., Anders, H. J. & Rees, A. J. The immune system and kidney disease: Basic concepts and clinical implications. Nat. Rev. Immunol. 13, 738-753 (2013
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 738-753
-
-
Kurts, C.1
Panzer, U.2
Anders, H.J.3
Rees, A.J.4
-
67
-
-
2542502538
-
Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice
-
Anders, H. J. et al. Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice. J. Am. Soc. Nephrol. 15, 1504-1513 (2004
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1504-1513
-
-
Anders, H.J.1
-
68
-
-
55849103960
-
Macrophage diversity in renal injury and repair
-
Ricardo, S. D., van Goor, H. & Eddy, A. A. Macrophage diversity in renal injury and repair. J. Clin. Invest. 118, 3522-3530 (2008
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3522-3530
-
-
Ricardo, S.D.1
Van Goor, H.2
Eddy, A.A.3
-
69
-
-
84886213424
-
B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis
-
Franois, A. et al. B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis. Arthritis Res. Ther. 15, R168 (2013
-
(2013)
Arthritis Res. Ther.
, vol.15
-
-
Franois, A.1
-
70
-
-
0242494298
-
Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis
-
Huaux, F. et al. Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis. J. Immunol. 171, 5470-5481 (2003
-
(2003)
J. Immunol.
, vol.171
, pp. 5470-5481
-
-
Huaux, F.1
-
71
-
-
39749178268
-
Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease Lab
-
Lebleu, V. S., Sugimoto, H., Miller, C. A., Gattone, V. H. 2nd & Kalluri, R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease, Lab. Invest. 88, 284-292 (2008
-
(2008)
Invest
, vol.88
, pp. 284-292
-
-
Lebleu, V.S.1
Sugimoto, H.2
Miller, C.A.3
Gattone, V.H.4
Kalluri, R.5
-
72
-
-
4644225081
-
IL-13 activates a mechanism of tissue fibrosis that is completely TGF- independent
-
Kaviratne, M. et al. IL-13 activates a mechanism of tissue fibrosis that is completely TGF- independent. J. Immunol. 173, 4020-4029 (2004
-
(2004)
J. Immunol.
, vol.173
, pp. 4020-4029
-
-
Kaviratne, M.1
-
73
-
-
0037903199
-
Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea
-
Elger, M. et al. Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea. J. Am. Soc. Nephrol. 14, 1506-1518 (2003
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1506-1518
-
-
Elger, M.1
-
74
-
-
33748059870
-
Regrow or repair: Potential regenerative therapies for the kidney
-
Little, M. H. Regrow or repair: Potential regenerative therapies for the kidney. J. Am. Soc. Nephrol. 17, 2390-2401 (2006
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2390-2401
-
-
Little, M.H.1
-
75
-
-
69249109548
-
Renal recovery after injury: The role of Pax-2. Nephrol
-
Lindoso, R. S., Verdoorn, K. S. & Einicker-Lamas, M. Renal recovery after injury: The role of Pax-2. Nephrol. Dial. Transplant. 24, 2628-2633 (2009
-
(2009)
Dial. Transplant.
, vol.24
, pp. 2628-2633
-
-
Lindoso, R.S.1
Verdoorn, K.S.2
Einicker-Lamas, M.3
-
76
-
-
34047237058
-
Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney
-
Narlis, M., Grote, D., Gaitan, Y., Boualia, S. K. & Bouchard, M. Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney, J. Am. Soc. Nephrol. 18, 1121-1129 (2007
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 1121-1129
-
-
Narlis, M.1
Grote, D.2
Gaitan, Y.3
Boualia, S.K.4
Bouchard, M.5
-
77
-
-
34447527647
-
Wnt/-catenin signaling regulates nephron induction during mouse kidney development
-
Park, J. S., Valerius, M. T. & McMahon, A. P. Wnt/-catenin signaling regulates nephron induction during mouse kidney development. Development 134, 2533-2539 (2007
-
(2007)
Development
, vol.134
, pp. 2533-2539
-
-
Park, J.S.1
Valerius, M.T.2
McMahon, A.P.3
-
78
-
-
78149492940
-
Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
-
Bramlage, C. P. et al. Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis. BMC Nephrol. 11, 31 (2010
-
(2010)
BMC Nephrol.
, vol.11
, pp. 31
-
-
Bramlage, C.P.1
-
79
-
-
0028832707
-
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
-
Dudley, A. T., Lyons, K. M. & Robertson, E. J. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9, 2795-2807 (1995
-
(1995)
Genes Dev.
, vol.9
, pp. 2795-2807
-
-
Dudley, A.T.1
Lyons, K.M.2
Robertson, E.J.3
-
80
-
-
0032128140
-
Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat
-
Vukicevic, S. et al. Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J. Clin. Invest. 102, 202-214 (1998
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 202-214
-
-
Vukicevic, S.1
-
81
-
-
34347375050
-
Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors
-
Sugimoto, H., Grahovac, G., Zeisberg, M. & Kalluri, R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes 56, 1825-1833 (2007
-
(2007)
Diabetes
, vol.56
, pp. 1825-1833
-
-
Sugimoto, H.1
Grahovac, G.2
Zeisberg, M.3
Kalluri, R.4
-
82
-
-
0035651361
-
Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function
-
Morrissey, J. et al. Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function. J. Am. Soc. Nephrol. 13 (Suppl. 1), S14-S21 (2002
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, Issue.SUPPL.1
-
-
Morrissey, J.1
-
83
-
-
14844290237
-
Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
-
Zeisberg, M., Shah, A. A. & Kalluri, R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J. Biol. Chem. 280, 8094-8100 (2005
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8094-8100
-
-
Zeisberg, M.1
Shah, A.A.2
Kalluri, R.3
-
84
-
-
37349044325
-
Expression and characterization of a human BMP-7 variant with improved biochemical properties
-
Swencki-Underwood, B. et al. Expression and characterization of a human BMP-7 variant with improved biochemical properties. Protein Expr. Purif. 57, 312-319 (2008
-
(2008)
Protein Expr. Purif.
, vol.57
, pp. 312-319
-
-
Swencki-Underwood, B.1
-
85
-
-
84858008133
-
Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis
-
Sugimoto, H. et al. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat. Med. 18, 396-404 (2012
-
(2012)
Nat. Med.
, vol.18
, pp. 396-404
-
-
Sugimoto, H.1
-
86
-
-
0020587101
-
Differentiation of cell types in the mammalian kidney by immunofluorescence microscopy using antibodies to intermediate filament proteins and desmoplakins
-
Bachmann, S., Kriz, W., Kuhn, C. & Franke, W. W. Differentiation of cell types in the mammalian kidney by immunofluorescence microscopy using antibodies to intermediate filament proteins and desmoplakins. Histochemistry 77, 365-394 (1983
-
(1983)
Histochemistry
, vol.77
, pp. 365-394
-
-
Bachmann, S.1
Kriz, W.2
Kuhn, C.3
Franke, W.W.4
-
87
-
-
84879772568
-
Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosis
-
Ebrahimi, B. et al. Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosis. PLoS ONE 8, e67474 (2013
-
(2013)
PLoS ONE
, vol.8
-
-
Ebrahimi, B.1
-
88
-
-
84861909097
-
Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis
-
Ebrahimi, B. et al. Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis. Am. J. Physiol. Renal Physiol. 302, F1478-F1485 (2012
-
(2012)
Am. J. Physiol. Renal Physiol.
, vol.302
-
-
Ebrahimi, B.1
-
89
-
-
84876510229
-
Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: Results of a phase i study
-
Reinders, M. E. et al. Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: Results of a phase I study. Stem Cells Transl. Med. 2, 107-111 (2013
-
(2013)
Stem Cells Transl. Med.
, vol.2
, pp. 107-111
-
-
Reinders, M.E.1
-
90
-
-
84863338204
-
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial
-
Tan, J. et al. Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial. JAMA 307, 1169-1177 (2012
-
(2012)
JAMA
, vol.307
, pp. 1169-1177
-
-
Tan, J.1
-
91
-
-
84874623698
-
Parthenogenetic stem cells for tissue-engineered heart repair
-
Didi, M. et al. Parthenogenetic stem cells for tissue-engineered heart repair. J. Clin. Invest. 123, 1285-1298 (2013
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1285-1298
-
-
Didi, M.1
-
92
-
-
80052933429
-
DNA demethylation dynamics
-
Bhutani, N., Burns, D. M. & Blau, H. M. DNA demethylation dynamics. Cell 146, 866-872 (2011
-
(2011)
Cell
, vol.146
, pp. 866-872
-
-
Bhutani, N.1
Burns, D.M.2
Blau, H.M.3
-
93
-
-
84880644265
-
Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis
-
Van Beneden, K. et al. Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis. Toxicol. Appl. Pharmacol. 271, 276-284 (2013
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.271
, pp. 276-284
-
-
Van Beneden, K.1
-
94
-
-
84890114778
-
HDAC dependent transcriptional repression of Bmp-7 potentiates TGF- mediated renal fibrosis in obstructive uropathy
-
Manson, S. R., Song, J. B., Hruska, K. A. & Austin, P. F. HDAC dependent transcriptional repression of Bmp-7 potentiates TGF- mediated renal fibrosis in obstructive uropathy. J. Urol. 191, 242-252 (2013
-
(2013)
J. Urol.
, vol.191
, pp. 242-252
-
-
Manson, S.R.1
Song, J.B.2
Hruska, K.A.3
Austin, P.F.4
-
95
-
-
84895902886
-
Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice
-
Reddy, M. A. et al. Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice. Kidney Int. http://dx.doi.org/10.1038/ ki.2013.387 (2013
-
(2013)
Kidney Int.
-
-
Reddy, M.A.1
-
96
-
-
84897111494
-
Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis
-
in press
-
Tampe, B. et al. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. J. Am. Soc. Nephrol. (in press
-
J. Am. Soc. Nephrol.
-
-
Tampe, B.1
-
97
-
-
20444426889
-
A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity
-
Kolfschoten, I. G. et al. A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell 121, 849-858 (2005
-
(2005)
Cell
, vol.121
, pp. 849-858
-
-
Kolfschoten, I.G.1
-
98
-
-
27744496468
-
Non-hydroxamate histone deacetylase inhibitors
-
Suzuki, T. & Miyata, N. Non-hydroxamate histone deacetylase inhibitors. Curr. Med. Chem. 12, 2867-2880 (2005
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 2867-2880
-
-
Suzuki, T.1
Miyata, N.2
-
99
-
-
0017253916
-
The disposition and pharmacokinetics in humans of 5-azacytidine administered intravenously as a bolus or by continuous infusion
-
Israili, Z. H. et al. The disposition and pharmacokinetics in humans of 5-azacytidine administered intravenously as a bolus or by continuous infusion. Cancer Res. 36, 1453-1461 (1976
-
(1976)
Cancer Res.
, vol.36
, pp. 1453-1461
-
-
Israili, Z.H.1
-
100
-
-
0742266631
-
The metabolic syndrome and chronic kidney disease in US adults
-
Chen, J. et al. The metabolic syndrome and chronic kidney disease in US adults. Ann. Intern. Med. 140, 167-174 (2004
-
(2004)
Ann. Intern. Med.
, vol.140
, pp. 167-174
-
-
Chen, J.1
-
101
-
-
84896713380
-
ACE inhibitor and angiotensin receptor blocker use and mortality in patients with chronic kidney disease
-
Molnar, M. Z. et al. ACE inhibitor and angiotensin receptor blocker use and mortality in patients with chronic kidney disease. J. Am. Coll. Cardiol. http://dx.doi.org/10.1016/j.jacc.2013.10.050 (2013
-
(2013)
J. Am. Coll. Cardiol.
-
-
Molnar, M.Z.1
-
102
-
-
84871197302
-
Accuracy of the MDRD (modification of diet in renal disease) study and CKD-EPI (CKD Epidemiology Collaboration) equations for estimation of GFR in the elderly
-
Kilbride, H. S. et al. Accuracy of the MDRD (modification of diet in renal disease) study and CKD-EPI (CKD Epidemiology Collaboration) equations for estimation of GFR in the elderly. Am. J. Kidney Dis. 61, 57-66 (2013
-
(2013)
Am. J. Kidney Dis.
, vol.61
, pp. 57-66
-
-
Kilbride, H.S.1
-
103
-
-
84905043459
-
The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study
-
Stengel, B. et al. The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study. Nephrol. Dial. Transplant. http://dx.doi.org/10.1093/ndt/gft388 (2013
-
(2013)
Nephrol. Dial. Transplant.
-
-
Stengel, B.1
-
104
-
-
84869100452
-
Relationship between ambulatory BP and clinical outcomes in patients with hypertensive CKD
-
Gabbai, F. B. et al. Relationship between ambulatory BP and clinical outcomes in patients with hypertensive CKD. Clin. J. Am. Soc. Nephrol. 7, 1770-1776 (2012
-
(2012)
Clin. J. Am. Soc. Nephrol.
, vol.7
, pp. 1770-1776
-
-
Gabbai, F.B.1
-
105
-
-
84855511123
-
Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl- proline: A blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors
-
Kanasaki, M., Nagai, T., Kitada, M., Koya, D. & Kanasaki, K. Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: A blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors. Fibrogenesis Tissue Repair 4, 25 (2011
-
(2011)
Fibrogenesis Tissue Repair
, vol.4
, pp. 25
-
-
Kanasaki, M.1
Nagai, T.2
Kitada, M.3
Koya, D.4
Kanasaki, K.5
-
106
-
-
78650502245
-
US renal data system annual data report
-
evii
-
Collins, A. J. et al. US Renal Data System Annual Data Report. Am. J. Kidney Dis. 59 (Suppl. 1), evii (2011
-
(2011)
Am. J. Kidney Dis.
, vol.59
, Issue.SUPPL.1
-
-
Collins, A.J.1
-
107
-
-
84857980619
-
Mechanistic insights into the antifibrotic activity of aliskiren in the kidney Hypertens
-
Zeisberg, M. & Mller, G. A. Mechanistic insights into the antifibrotic activity of aliskiren in the kidney, Hypertens. Res. 35, 266-268 (2012
-
(2012)
Res.
, vol.35
, pp. 266-268
-
-
Zeisberg, M.1
Mller, G.A.2
-
108
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to rennin
-
Nguyen, G. et al. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J. Clin. Invest. 109, 1417-1427 (2002
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
-
109
-
-
46449118638
-
Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
-
Feldman, D. L. et al. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 52, 130-136 (2008
-
(2008)
Hypertension
, vol.52
, pp. 130-136
-
-
Feldman, D.L.1
-
110
-
-
84873737622
-
ALTITUDE trial and dual RAS blockade: The alluring but soft science of the surrogate end point
-
Messerli, F. H. & Bangalore, S. ALTITUDE trial and dual RAS blockade: The alluring but soft science of the surrogate end point. Am. J. Med. 126, e1-e3 (2013
-
(2013)
Am. J. Med.
, vol.126
-
-
Messerli, F.H.1
Bangalore, S.2
-
111
-
-
84893083410
-
Risk for end-stage renal isease over 25 years in the population-based WESDR cohort
-
Lecaire, T. J., Klein, B. E., Howard, K. P., Lee, K. E. & Klein, R. Risk for end-stage renal isease over 25 years in the population-based WESDR cohort. Diabetes Care 37, 381-388 (2013
-
(2013)
Diabetes Care
, vol.37
, pp. 381-388
-
-
Lecaire, T.J.1
Klein, B.E.2
Howard, K.P.3
Lee, K.E.4
Klein, R.5
-
112
-
-
0025277164
-
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor 1
-
Border, W. A., Okuda, S., Languino, L. R., Sporn, M. B. & Ruoslahti, E. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor 1. Nature 346, 371-374 (1990
-
(1990)
Nature
, vol.346
, pp. 371-374
-
-
Border, W.A.1
Okuda, S.2
Languino, L.R.3
Sporn, M.B.4
Ruoslahti, E.5
-
113
-
-
0026676859
-
Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease
-
Border, W. A. et al. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature 360, 361-364 (1992
-
(1992)
Nature
, vol.360
, pp. 361-364
-
-
Border, W.A.1
-
114
-
-
0029905441
-
Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
-
Isaka, Y. et al. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat. Med. 2, 418-423 (1996
-
(1996)
Nat. Med.
, vol.2
, pp. 418-423
-
-
Isaka, Y.1
-
115
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT00464321 (2010
-
(2010)
ClinicalTrials
-
-
-
116
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01113801 (2013
-
(2013)
ClinicalTrials
-
-
-
117
-
-
73449089494
-
Companies waver in efforts to target transforming growth factor in cancer
-
Garber, K. Companies waver in efforts to target transforming growth factor in cancer. J. Natl Cancer Inst. 101, 1664-1667 (2009
-
(2009)
J. Natl Cancer Inst.
, vol.101
, pp. 1664-1667
-
-
Garber, K.1
-
118
-
-
0036084359
-
TGF- antagonists: Why suppress a tumor suppressor
-
Akhurst, R. J. TGF- antagonists: why suppress a tumor suppressor J. Clin. Invest. 109, 1533-1536 (2002
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1533-1536
-
-
Akhurst, R.J.1
-
119
-
-
0034574298
-
How cells read TGF- Signals
-
Massagu, J. How cells read TGF- signals. Nat. Rev. Mol. Cell Biol. 1, 169-178 (2000
-
(2000)
Nat. Rev. Mol. Cell Biol.
, vol.1
, pp. 169-178
-
-
Massagu, J.1
-
120
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
Zeisberg, M. et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J. Biol. Chem. 282, 23337-23347 (2007
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23337-23347
-
-
Zeisberg, M.1
-
121
-
-
17544379605
-
Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction
-
Hruska, K. A. et al. Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction. Am. J. Physiol. Renal Physiol. 279, F130-F143 (2000
-
(2000)
Am. J. Physiol. Renal Physiol.
, vol.279
-
-
Hruska, K.A.1
-
122
-
-
0037405422
-
BMP7 antagonizes TGF-dependent fibrogenesis in mesangial cells
-
Wang, S. & Hirschberg, R. BMP7 antagonizes TGF-dependent fibrogenesis in mesangial cells. Am. J. Physiol. Renal Physiol. 284, F1006-F1013 (2003
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.284
-
-
Wang, S.1
Hirschberg, R.2
-
123
-
-
34547676391
-
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
-
Zeisberg, E. M. et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat. Med. 13, 952-961 (2007
-
(2007)
Nat. Med.
, vol.13
, pp. 952-961
-
-
Zeisberg, E.M.1
-
124
-
-
77953769774
-
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis
-
Flier, S. N. et al. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J. Biol. Chem. 285, 20202-20212 (2010
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 20202-20212
-
-
Flier, S.N.1
-
125
-
-
0026055366
-
Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
-
Bradham, D. M., Igarashi, A., Potter, R. L. & Grotendorst, G. R. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J. Cell Biol. 114, 1285-1294 (1991
-
(1991)
J. Cell Biol.
, vol.114
, pp. 1285-1294
-
-
Bradham, D.M.1
Igarashi, A.2
Potter, R.L.3
Grotendorst, G.R.4
-
126
-
-
48649102468
-
Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy
-
Nguyen, T. Q. et al. Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy. Diabetes Care 31, 1177-1182 (2008
-
(2008)
Diabetes Care
, vol.31
, pp. 1177-1182
-
-
Nguyen, T.Q.1
-
127
-
-
2542473312
-
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis
-
Yokoi, H. et al. Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J. Am. Soc. Nephrol. 15, 1430-1440 (2004
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1430-1440
-
-
Yokoi, H.1
-
128
-
-
35248841125
-
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
-
Guha, M., Xu, Z. G., Tung, D., Lanting, L. & Natarajan, R. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. FASEB J. 21, 3355-3368 (2007
-
(2007)
FASEB J.
, vol.21
, pp. 3355-3368
-
-
Guha, M.1
Xu, Z.G.2
Tung, D.3
Lanting, L.4
Natarajan, R.5
-
129
-
-
77955743198
-
Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria
-
Adler, S. G. et al. Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria. Clin. J. Am. Soc. Nephrol. 5, 1420-1428 (2010
-
(2010)
Clin. J. Am. Soc. Nephrol.
, vol.5
, pp. 1420-1428
-
-
Adler, S.G.1
-
130
-
-
77951160564
-
Pirfenidone in idiopathic pulmonary fibrosis
-
Taniguchi, H. et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur. Respir. J. 35, 821-829 (2010
-
(2010)
Eur. Respir. J.
, vol.35
, pp. 821-829
-
-
Taniguchi, H.1
-
131
-
-
0031834709
-
Pirfenidone improves renal function and fibrosis in the post-obstructed kidney
-
Shimizu, T. et al. Pirfenidone improves renal function and fibrosis in the post-obstructed kidney. Kidney Int. 54, 99-109 (1998
-
(1998)
Kidney Int.
, vol.54
, pp. 99-109
-
-
Shimizu, T.1
-
132
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor- antibody in db/db diabetic mice
-
Ziyadeh, F. N. et al. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor- antibody in db/db diabetic mice. Proc. Natl Acad. Sci. USA 97, 8015-8020 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
-
133
-
-
68149178848
-
Pirfenidone is renoprotective in diabetic kidney disease
-
RamachandraRao, S. P. et al. Pirfenidone is renoprotective in diabetic kidney disease. J. Am. Soc. Nephrol. 20, 1765-1775 (2009
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1765-1775
-
-
Ramachandrarao, S.P.1
-
134
-
-
34548834734
-
Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis
-
Cho, M. E., Smith, D. C., Branton, M. H., Penzak, S. R. & Kopp, J. B. Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis. Clin. J. Am. Soc. Nephrol. 2, 906-913 (2007
-
(2007)
Clin. J. Am. Soc. Nephrol.
, vol.2
, pp. 906-913
-
-
Cho, M.E.1
Smith, D.C.2
Branton, M.H.3
Penzak, S.R.4
Kopp, J.B.5
-
135
-
-
79957670746
-
Pirfenidone for diabetic nephropathy
-
Sharma, K. et al. Pirfenidone for diabetic nephropathy. J. Am. Soc. Nephrol. 22, 1144-1151 (2011
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 1144-1151
-
-
Sharma, K.1
-
136
-
-
32144454172
-
The many roles of chemokines and chemokine receptors in inflammation
-
Charo, I. F. & Ransohoff, R. M. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354, 610-621 (2006
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
137
-
-
84891960758
-
Chemokines in tumor progression and metastasis
-
Sarvaiya, P. J., Guo, D., Ulasov, I., Gabikian, P. & Lesniak, M. S. Chemokines in tumor progression and metastasis. Oncotarget 4, 2171-2185 (2013
-
(2013)
Oncotarget
, vol.4
, pp. 2171-2185
-
-
Sarvaiya, P.J.1
Guo, D.2
Ulasov, I.3
Gabikian, P.4
Lesniak, M.S.5
-
138
-
-
0037252248
-
Chemokines and chemokine receptors are involved in the resolution or progression of renal disease
-
Anders, H. J., Vielhauer, V. & Schlondorff, D. Chemokines and chemokine receptors are involved in the resolution or progression of renal disease. Kidney Int. 63, 401-415 (2003
-
(2003)
Kidney Int.
, vol.63
, pp. 401-415
-
-
Anders, H.J.1
Vielhauer, V.2
Schlondorff, D.3
-
139
-
-
84879693711
-
Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model
-
Reich, B. et al. Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model. Kidney Int. 84, 78-89 (2013
-
(2013)
Kidney Int.
, vol.84
, pp. 78-89
-
-
Reich, B.1
-
140
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01447147 (2013
-
(2013)
ClinicalTrials
-
-
-
141
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01440257 (2013
-
(2013)
ClinicalTrials
-
-
-
142
-
-
84887006703
-
CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice
-
Sullivan, T. et al. CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice. Am. J. Physiol. Renal Physiol. 305, F1288-F1297 (2013
-
(2013)
Am. J. Physiol. Renal Physiol.
, vol.305
-
-
Sullivan, T.1
-
143
-
-
84878002397
-
Orally-administered chemokine receptor CCR2 antagonist CCX140-B in type 2 diabetes: A pilot double-blind, randomized clinical trial
-
Hanefeld, M. et al. Orally-administered chemokine receptor CCR2 antagonist CCX140-B in type 2 diabetes: A pilot double-blind, randomized clinical trial. J. Diabetes Metab. 3, 225 (2012
-
(2012)
J. Diabetes Metab.
, vol.3
, pp. 225
-
-
Hanefeld, M.1
-
144
-
-
0024427985
-
The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression
-
Inoue, A. et al. The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression. J. Biol. Chem. 264, 14954-14959 (1989
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 14954-14959
-
-
Inoue, A.1
-
145
-
-
0025805940
-
Chromosomal assignments of the human endothelin family genes: The endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3
-
Arinami, T. et al. Chromosomal assignments of the human endothelin family genes: The endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3. Am. J. Hum. Genet. 48, 990-996 (1991
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 990-996
-
-
Arinami, T.1
-
146
-
-
0029843759
-
Endothelin peptides and receptors in human kidney
-
Karet, F. E. Endothelin peptides and receptors in human kidney, Clin. Sci. (Lond.) 91, 267-273 (1996
-
(1996)
Clin. Sci. (Lond.)
, vol.91
, pp. 267-273
-
-
Karet, F.E.1
-
147
-
-
33645472590
-
The endothelin system and its antagonism in chronic kidney disease
-
Dhaun, N., Goddard, J. & Webb, D. J. The endothelin system and its antagonism in chronic kidney disease J. Am. Soc. Nephrol. 17, 943-955 (2006
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 943-955
-
-
Dhaun, N.1
Goddard, J.2
Webb, D.J.3
-
148
-
-
20044366257
-
Endothelin antagonism in pulmonary hypertension, heart failure, and beyond
-
Attin, T., Camidge, R., Newby, D. E. & Webb, D. J. Endothelin antagonism in pulmonary hypertension, heart failure, and beyond. Heart 91, 825-831 (2005
-
(2005)
Heart
, vol.91
, pp. 825-831
-
-
Attin, T.1
Camidge, R.2
Newby, D.E.3
Webb, D.J.4
-
149
-
-
0032005875
-
Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells
-
Wesson, D. E., Simoni, J. & Green, D. F. Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells. J. Clin. Invest. 101, 578-583 (1998
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 578-583
-
-
Wesson, D.E.1
Simoni, J.2
Green, D.F.3
-
150
-
-
0034047909
-
Transgenic animal models for the analysis of the renal endothelin system
-
Hocher, B. & Paul, M. Transgenic animal models for the analysis of the renal endothelin system. Nephrol. Dial. Transplant. 15, 935-937 (2000
-
(2000)
Nephrol. Dial. Transplant.
, vol.15
, pp. 935-937
-
-
Hocher, B.1
Paul, M.2
-
151
-
-
0025314793
-
Application of monoclonal antibodies for endothelin to hypertensive research
-
Saito, Y. et al. Application of monoclonal antibodies for endothelin to hypertensive research. Hypertension 15, 734-738 (1990
-
(1990)
Hypertension
, vol.15
, pp. 734-738
-
-
Saito, Y.1
-
152
-
-
11144314951
-
Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera
-
Kuc, R. & Davenport, A. P. Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera. J. Cardiovasc. Pharmacol. 44 (Suppl. 1), S224-S226 (2004
-
(2004)
J. Cardiovasc. Pharmacol.
, vol.44
, Issue.SUPPL.1
-
-
Kuc, R.1
Davenport, A.P.2
-
153
-
-
0027203495
-
A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression
-
Benigni, A. et al. A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. Kidney Int. 44, 440-444 (1993
-
(1993)
Kidney Int.
, vol.44
, pp. 440-444
-
-
Benigni, A.1
-
154
-
-
33750238503
-
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension
-
Opocensk, M. et al. Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension. Hypertension 48, 965-971 (2006
-
(2006)
Hypertension
, vol.48
, pp. 965-971
-
-
Opocensk, M.1
-
155
-
-
0035090401
-
Regression of renal vascular fibrosis by endothelin receptor antagonism
-
Boffa, J. J., Tharaux, P. L., Dussaule, J. C. & Chatziantoniou, C. Regression of renal vascular fibrosis by endothelin receptor antagonism. Hypertension 37, 490-496 (2001
-
(2001)
Hypertension
, vol.37
, pp. 490-496
-
-
Boffa, J.J.1
Tharaux, P.L.2
Dussaule, J.C.3
Chatziantoniou, C.4
-
156
-
-
0029963298
-
Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth
-
Gmez-Garre, D. et al. Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension 27, 885-892 (1996
-
(1996)
Hypertension
, vol.27
, pp. 885-892
-
-
Gmez-Garre, D.1
-
157
-
-
0029991748
-
Role of endothelin as a mitogen in experimental glomerulonephritis in rats
-
Fukuda, K. et al. Role of endothelin as a mitogen in experimental glomerulonephritis in rats, Kidney Int. 49, 1320-1329 (1996
-
(1996)
Kidney Int.
, vol.49
, pp. 1320-1329
-
-
Fukuda, K.1
-
158
-
-
0031871078
-
Renoprotective effect of contemporary blocking of angiotensin II and endothelin-1 in rats with membranous nephropathy
-
Benigni, A. et al. Renoprotective effect of contemporary blocking of angiotensin II and endothelin-1 in rats with membranous nephropathy. Kidney Int. 54, 353-359 (1998
-
(1998)
Kidney Int.
, vol.54
, pp. 353-359
-
-
Benigni, A.1
-
159
-
-
79959526176
-
Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J. Pharmacol
-
Saleh, M. A., Pollock, J. S. & Pollock, D. M. Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J. Pharmacol. Exp. Ther. 338, 263-270 (2011
-
(2011)
Exp. Ther.
, vol.338
, pp. 263-270
-
-
Saleh, M.A.1
Pollock, J.S.2
Pollock, D.M.3
-
160
-
-
62149126622
-
Avosentan reduces albumin excretion in diabetics with macroalbuminuria
-
Wenzel, R. R. et al. Avosentan reduces albumin excretion in diabetics with macroalbuminuria. J. Am. Soc. Nephrol. 20, 655-664 (2009
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 655-664
-
-
Wenzel, R.R.1
-
161
-
-
77949877308
-
Avosentan for overt diabetic nephropathy
-
Mann, J. F. et al. Avosentan for overt diabetic nephropathy. J. Am. Soc. Nephrol. 21, 527-535 (2010
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 527-535
-
-
Mann, J.F.1
-
162
-
-
0033119248
-
Pentoxifylline inhibits PDGF-induced proliferation of and TGF-stimulated collagen synthesis by vascular smooth muscle cells
-
Chen, Y. M., Wu, K. D., Tsai, T. J. & Hsieh, B. S. Pentoxifylline inhibits PDGF-induced proliferation of and TGF-stimulated collagen synthesis by vascular smooth muscle cells. J. Mol. Cell Cardiol. 31, 773-783 (1999
-
(1999)
J. Mol. Cell Cardiol.
, vol.31
, pp. 773-783
-
-
Chen, Y.M.1
Wu, K.D.2
Tsai, T.J.3
Hsieh, B.S.4
-
163
-
-
0033810053
-
Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts
-
Strutz, F. et al. Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts. Nephrol. Dial. Transplant. 15, 1535-1546 (2000
-
(2000)
Nephrol. Dial. Transplant.
, vol.15
, pp. 1535-1546
-
-
Strutz, F.1
-
164
-
-
0036892615
-
Pentoxifylline attenuated the renal disease progression in rats with remnant kidney
-
Lin, S. L. et al. Pentoxifylline attenuated the renal disease progression in rats with remnant kidney. J. Am. Soc. Nephrol. 13, 2916-2929 (2002
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2916-2929
-
-
Lin, S.L.1
-
165
-
-
33745921200
-
Effects of pentoxifylline on the urinary protein excretion profile of type 2 diabetic patients with microproteinuria: A double-blind, placebo-controlled randomized trial
-
Rodriguez-Morn, M. et al. Effects of pentoxifylline on the urinary protein excretion profile of type 2 diabetic patients with microproteinuria: A double-blind, placebo-controlled randomized trial. Clin. Nephrol. 66, 3-10 (2006
-
(2006)
Clin. Nephrol.
, vol.66
, pp. 3-10
-
-
Rodriguez-Morn, M.1
-
166
-
-
62749098612
-
Effect of pentoxifylline on GFR decline in CKD: A pilot, double-blind, randomized, placebo-controlled trial
-
Perkins, R. M. et al. Effect of pentoxifylline on GFR decline in CKD: A pilot, double-blind, randomized, placebo-controlled trial. Am. J. Kidney Dis. 53, 606-616 (2009
-
(2009)
Am. J. Kidney Dis.
, vol.53
, pp. 606-616
-
-
Perkins, R.M.1
-
167
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01377285 (2013
-
(2013)
ClinicalTrials
-
-
-
168
-
-
0034998032
-
Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction
-
Zalba, G. et al. Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction Nephrol. Dial. Transplant. 16 (Suppl. 1), 2-5 (2001
-
(2001)
Nephrol. Dial. Transplant.
, vol.16
, Issue.SUPPL.1
, pp. 2-5
-
-
Zalba, G.1
-
169
-
-
21744449051
-
In vivo and in vitro response of corpus cavernosum to phosphodiesterase-5 inhibition in the hypercholesterolaemic rabbit
-
Firoozi, F., Longhurst, P. A. & White, M. D. In vivo and in vitro response of corpus cavernosum to phosphodiesterase-5 inhibition in the hypercholesterolaemic rabbit. BJU Int. 96, 164-168 (2005
-
(2005)
BJU Int.
, vol.96
, pp. 164-168
-
-
Firoozi, F.1
Longhurst, P.A.2
White, M.D.3
-
170
-
-
0032924098
-
Cyclic-3,5-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney
-
Dousa, T. P. Cyclic-3,5-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney. Kidney Int. 55, 29-62 (1999
-
(1999)
Kidney Int.
, vol.55
, pp. 29-62
-
-
Dousa, T.P.1
-
171
-
-
35649007812
-
The effect of vardenafil (a PDE type 5 inhibitor) on renal function in the diabetic rabbit: A pilot study
-
Lau, D. H., Mikhailidis, D. P. & Thompson, C. S. The effect of vardenafil (a PDE type 5 inhibitor) on renal function in the diabetic rabbit: A pilot study. In Vivo 21, 851-854 (2007
-
(2007)
Vivo
, vol.21
, pp. 851-854
-
-
Lau, D.H.1
Mikhailidis, D.P.2
Thompson, C.S.3
-
172
-
-
52149122499
-
Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats
-
Jeong, K. H. et al. Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats. Am. J. Nephrol. 29, 274-282 (2009
-
(2009)
Am. J. Nephrol.
, vol.29
, pp. 274-282
-
-
Jeong, K.H.1
-
173
-
-
77951473694
-
-
US National Library of Medicine gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/show/NCT01200394 (2013
-
(2013)
ClinicalTrials
-
-
-
174
-
-
0036548475
-
Reactive oxygen species: Roles in blood pressure and kidney function
-
Wilcox, C. S. Reactive oxygen species: Roles in blood pressure and kidney function. Curr. Hypertens. Rep. 4, 160-166 (2002
-
(2002)
Curr. Hypertens. Rep.
, vol.4
, pp. 160-166
-
-
Wilcox, C.S.1
-
175
-
-
1642369185
-
Reactive oxygen species in vascular biology: Role in arterial hypertension
-
Touyz, R. M. Reactive oxygen species in vascular biology: Role in arterial hypertension. Expert Rev. Cardiovasc. Ther. 1, 91-106 (2003
-
(2003)
Expert Rev. Cardiovasc. Ther.
, vol.1
, pp. 91-106
-
-
Touyz, R.M.1
-
176
-
-
33749045289
-
Mechanisms of disease: Oxidative stress and inflammation in the pathogenesis of hypertension
-
Vaziri, N. D. & Rodriguez-Iturbe, B. Mechanisms of disease: Oxidative stress and inflammation in the pathogenesis of hypertension. Nat. Clin. Pract. Nephrol. 2, 582-593 (2006
-
(2006)
Nat. Clin. Pract. Nephrol.
, vol.2
, pp. 582-593
-
-
Vaziri, N.D.1
Rodriguez-Iturbe, B.2
-
177
-
-
12844254768
-
ATVB in focus: Redox mechanisms in blood vessels Arterioscler
-
Mueller, C. F., Laude, K., McNally, J. S. & Harrison, D. G. ATVB in focus: Redox mechanisms in blood vessels, Arterioscler. Thromb. Vasc. Biol. 25, 274-278 (2005
-
(2005)
Thromb. Vasc. Biol.
, vol.25
, pp. 274-278
-
-
Mueller, C.F.1
Laude, K.2
McNally, J.S.3
Harrison, D.G.4
-
178
-
-
33750923115
-
NADPH oxidases: New regulators of old functions
-
Griendling, K. K. NADPH oxidases: New regulators of old functions. Antioxid. Redox Signal. 8, 1443-1445 (2006
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1443-1445
-
-
Griendling, K.K.1
-
179
-
-
0042810670
-
Vascular NAD(P)H oxidases: Specific features, expression, and regulation
-
Lassegue, B. & Clempus, R. E. Vascular NAD(P)H oxidases: Specific features, expression, and regulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R277-R297 (2003
-
(2003)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.285
-
-
Lassegue, B.1
Clempus, R.E.2
-
180
-
-
0030005713
-
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
-
Rajagopalan, S. et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 97, 1916-1923 (1996
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1916-1923
-
-
Rajagopalan, S.1
-
181
-
-
1642276271
-
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
-
Virdis, A., Neves, M. F., Amiri, F., Touyz, R. M. & Schiffrin, E. L. Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J. Hypertens. 22, 535-542 (2004
-
(2004)
J. Hypertens.
, vol.22
, pp. 535-542
-
-
Virdis, A.1
Neves, M.F.2
Amiri, F.3
Touyz, R.M.4
Schiffrin, E.L.5
-
182
-
-
84866950669
-
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent
-
Aoyama, T. et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology 56, 2316-2327 (2012
-
(2012)
Hepatology
, vol.56
, pp. 2316-2327
-
-
Aoyama, T.1
-
183
-
-
7744232120
-
Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension
-
Fortuo, A. et al. Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension. J. Hypertens. 22, 2169-2175 (2004
-
(2004)
J. Hypertens.
, vol.22
, pp. 2169-2175
-
-
Fortuo, A.1
-
184
-
-
0037142088
-
Endothelial function and oxidative stress in renovascular hypertension
-
Higashi, Y. et al. Endothelial function and oxidative stress in renovascular hypertension. N. Engl. J. Med. 346, 1954-1962 (2002
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1954-1962
-
-
Higashi, Y.1
-
185
-
-
0036107634
-
Oxidative stress in malignant and non-malignant phase hypertension
-
Lip, G. Y. et al. Oxidative stress in malignant and non-malignant phase hypertension. J. Hum. Hypertens. 16, 333-336 (2002
-
(2002)
J. Hum. Hypertens.
, vol.16
, pp. 333-336
-
-
Lip, G.Y.1
|