Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level

Metabolism: Clinical and Experimental

Volumn 61, Issue 8, 2012, Pages 1067-1072

  Ishibashi, Yuji ^a   Yamagishi, Sho Ichi ^a   Matsui, Takanori ^a   Ohta, Keisuke ^a   Tanoue, Ryuichiro ^a   Takeuchi, Masayoshi ^b   Ueda, Seiji ^a   Nakamura, Kei Ichiro ^a   Okuda, Seiya ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Ab; Ab raised against RAGE; ADMA; advanced glycation end products; AGEs; antibody; asymmetric dimethylarginine; bovine serum albumin; BSA; chronic kidney disease; CKD; DDAH2; DHE; dihydroethidium; dimethylarginine dimethylaminohydrolase 2; geranylgeranyl pyrophosphate; GGPP; RAGE; RAGE Ab; reactive oxygen species; receptor for AGEs; reverse transcription polymerase chain reactions; ROS; RT PCR; SEM; standard error

Indexed keywords

ADVANCED GLYCATION END PRODUCT; DIMETHYLARGININASE; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 2; GERANYLGERANYL PYROPHOSPHATE; HYDROETHIDINE; MESSENGER RNA; N(G),N(G) DIMETHYLARGININE; PRAVASTATIN; REACTIVE OXYGEN METABOLITE; ROSUVASTATIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE DAMAGE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING;

AMIDOHYDROLASES; APOPTOSIS; ARGININE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FLUOROBENZENES; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KIDNEY TUBULES, PROXIMAL; PRAVASTATIN; PYRIMIDINES; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFONAMIDES; UP-REGULATION;

EID: 84864287672     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.01.006     Document Type: Article

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