Aldose reductase regulates platelet-derived growth factor-induced proliferation through mediating cell cycle progression in rat mesangial cells

International Journal of Molecular Medicine

Volumn 30, Issue 2, 2012, Pages 409-416

  Zou, Liping ^a   Wang, Wenjuan ^a   Xu, Zude ^a,b   Zhang, Nong ^b   Jiang, Tao ^b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Aldose reductase; Mesangial cell; p21 Cip1; p27 Kip1; PI3K Akt; Platelet derived growth factor

Indexed keywords

ALDEHYDE REDUCTASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; ZOPOLRESTAT;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; INTRACELLULAR SIGNALING; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ALDEHYDE REDUCTASE; ANIMALS; BENZOTHIAZOLES; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENZYME ACTIVATION; MESANGIAL CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PHTHALAZINES; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA;

EID: 84863548620     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.997     Document Type: Article

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