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Volumn 80, Issue 11, 2011, Pages 1159-1169

Canonical Wnt/Β-catenin signaling mediates transforming growth factor-Β1-driven podocyte injury and proteinuria

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CALVASCULIN; DESMIN; DICKKOPF 1 PROTEIN; GELATINASE B; MATRILYSIN; NEPHRIN; PROTEIN INHIBITOR; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEIN;

EID: 81155150123     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.255     Document Type: Article
Times cited : (136)

References (49)
  • 1
    • 70349330816 scopus 로고    scopus 로고
    • New insights into the role of podocytes in proteinuria
    • Patrakka J, Tryggvason K. New insights into the role of podocytes in proteinuria. Nat Rev Nephrol 2009; 5: 463-468.
    • (2009) Nat Rev Nephrol , vol.5 , pp. 463-468
    • Patrakka, J.1    Tryggvason, K.2
  • 2
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: A unifying view of glomerular diseases
    • DOI 10.1038/sj.ki.5002222, PII 5002222
    • Wiggins RC. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int 2007; 71: 1205-1214. (Pubitemid 46884251)
    • (2007) Kidney International , vol.71 , Issue.12 , pp. 1205-1214
    • Wiggins, R.C.1
  • 3
    • 33745058119 scopus 로고    scopus 로고
    • The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
    • DOI 10.1038/sj.ki.5000410, PII 5000410
    • Shankland SJ. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int 2006; 69: 2131-2147. (Pubitemid 43882099)
    • (2006) Kidney International , vol.69 , Issue.12 , pp. 2131-2147
    • Shankland, S.J.1
  • 4
    • 63849233538 scopus 로고    scopus 로고
    • TGF-beta signal transduction in chronic kidney disease
    • Schnaper HW, Jandeska S, Runyan CE et al. TGF-beta signal transduction in chronic kidney disease. Front Biosci 2009; 14: 2448-2465.
    • (2009) Front Biosci , vol.14 , pp. 2448-2465
    • Schnaper, H.W.1    Jandeska, S.2    Runyan, C.E.3
  • 5
    • 0036786834 scopus 로고    scopus 로고
    • TGF-beta signaling in renal disease
    • Bottinger EP, Bitzer M. TGF-beta signaling in renal disease. J Am Soc Nephrol 2002; 13: 2600-2610.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2610
    • Bottinger, E.P.1    Bitzer, M.2
  • 6
    • 39549098861 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
    • DOI 10.2353/ajpath.2008.070057
    • Li Y, Kang YS, Dai C et al. Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol 2008; 172: 299-308. (Pubitemid 351282018)
    • (2008) American Journal of Pathology , vol.172 , Issue.2 , pp. 299-308
    • Li, Y.1    Kang, Y.S.2    Dai, C.3    Kiss, L.P.4    Wen, X.5    Liu, Y.6
  • 7
    • 33644877366 scopus 로고    scopus 로고
    • TGF-β concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes
    • DOI 10.1681/ASN.2004121055
    • Wu DT, Bitzer M, Ju W et al. TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. J Am Soc Nephrol 2005; 16: 3211-3221. (Pubitemid 46179327)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.11 , pp. 3211-3221
    • Wu, D.T.1    Bitzer, M.2    Ju, W.3    Mundel, P.4    Bottinger, E.P.5
  • 10
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 11
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S, Moon RT. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009; 10: 468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 12
    • 53049088426 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny
    • Schmidt-Ott KM, Barasch J. WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Kidney Int 2008; 74: 1004-1008.
    • (2008) Kidney Int , vol.74 , pp. 1004-1008
    • Schmidt-Ott, K.M.1    Barasch, J.2
  • 13
    • 22944463010 scopus 로고    scopus 로고
    • Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system
    • DOI 10.1016/j.devcel.2005.05.016, PII S1534580705001863
    • Carroll TJ, Park JS, Hayashi S et al. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 2005; 9: 283-292. (Pubitemid 41051746)
    • (2005) Developmental Cell , vol.9 , Issue.2 , pp. 283-292
    • Carroll, T.J.1    Park, J.-S.2    Hayashi, S.3    Majumdar, A.4    McMahon, A.P.5
  • 14
    • 65249134946 scopus 로고    scopus 로고
    • Wnt/b-catenin signaling promotes renal interstitial fibrosis
    • He W, Dai C, Li Y et al. Wnt/b-catenin signaling promotes renal interstitial fibrosis. J Am Soc Nephrol 2009; 20: 765-776.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 765-776
    • He, W.1    Dai, C.2    Li, Y.3
  • 15
    • 69849089270 scopus 로고    scopus 로고
    • Wnt/b-catenin signaling promotes podocyte dysfunction and albuminuria
    • Dai C, Stolz DB, Kiss LP et al. Wnt/b-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 2009; 20: 1997-2008.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1997-2008
    • Dai, C.1    Stolz, D.B.2    Kiss, L.P.3
  • 16
    • 70349222997 scopus 로고    scopus 로고
    • Wnt pathway regulation in chronic renal allograft damage
    • von Toerne C, Schmidt C, Adams J et al. Wnt pathway regulation in chronic renal allograft damage. Am J Transplant 2009; 9: 2223-2239.
    • (2009) Am J Transplant , vol.9 , pp. 2223-2239
    • Von Toerne, C.1    Schmidt, C.2    Adams, J.3
  • 17
    • 28444468088 scopus 로고    scopus 로고
    • Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
    • DOI 10.1681/ASN.2004110949
    • Surendran K, Schiavi S, Hruska KA. Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J Am Soc Nephrol 2005; 16: 2373-2384. (Pubitemid 41725055)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.8 , pp. 2373-2384
    • Surendran, K.1    Schiavi, S.2    Hruska, K.A.3
  • 18
    • 77953530356 scopus 로고    scopus 로고
    • B-Catenin mediates adriamycin-induced albuminuria and podocyte injury in the adult mouse kidneys
    • Heikkila E, Juhila J, Lassila M et al. b-Catenin mediates adriamycin-induced albuminuria and podocyte injury in the adult mouse kidneys. Nephrol Dial Transplant 2010; 25: 2437-2446.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2437-2446
    • Heikkila, E.1    Juhila, J.2    Lassila, M.3
  • 19
    • 78651384347 scopus 로고    scopus 로고
    • Blockade of Wnt/b-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury
    • He W, Kang YS, Dai C et al. Blockade of Wnt/b-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. J Am Soc Nephrol 2011; 22: 90-103.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 90-103
    • He, W.1    Kang, Y.S.2    Dai, C.3
  • 20
    • 0035954281 scopus 로고    scopus 로고
    • Head inducer dickkopf-1 is a ligand for Wnt coreceptor LRP6
    • DOI 10.1016/S0960-9822(01)00290-1
    • Semenov MV, Tamai K, Brott BK et al. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 2001; 11: 951-961. (Pubitemid 32589186)
    • (2001) Current Biology , vol.11 , Issue.12 , pp. 951-961
    • Semenov, M.V.1    Tamai, K.2    Brott, B.K.3    Kuhl, M.4    Sokol, S.5    He, X.6
  • 21
    • 0036156658 scopus 로고    scopus 로고
    • Single injection of naked plasmid encoding hepatocyte growth factor prevents cell death and ameliorates acute renal failure in mice
    • Dai C, Yang J, Liu Y. Single injection of naked plasmid encoding hepatocyte growth factor prevents cell death and ameliorates acute renal failure in mice. J Am Soc Nephrol 2002; 13: 411-422. (Pubitemid 34106284)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.2 , pp. 411-422
    • Dai, C.1    Yang, J.2    Liu, Y.3
  • 22
    • 0035080761 scopus 로고    scopus 로고
    • Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth
    • DOI 10.1053/jhep.2001.23438
    • Yang J, Chen S, Huang L et al. Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth. Hepatology 2001; 33: 848-859. (Pubitemid 32246634)
    • (2001) Hepatology , vol.33 , Issue.4 , pp. 848-859
    • Yang, J.1    Chen, S.2    Huang, L.3    Michalopoulos, G.K.4    Liu, Y.5
  • 23
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice
    • DOI 10.1097/01.ASN.0000139479.09658.EE
    • Dai C, Yang J, Bastacky S et al. Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice. J Am Soc Nephrol 2004; 15: 2637-2647. (Pubitemid 41103370)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.10 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3    Xia, J.4    Li, Y.5    Liu, Y.6
  • 24
    • 0024312217 scopus 로고
    • Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor β1 precursor. Expression and characterization of mutant proteins
    • Brunner AM, Marquardt H, Malacko AR et al. Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins. J Biol Chem 1989; 264: 13660-13664. (Pubitemid 19198449)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.23 , pp. 13660-13664
    • Brunner, A.M.1    Marquardt, H.2    Malacko, A.R.3    Lioubin, M.N.4    Purchio, A.F.5
  • 25
    • 77955286565 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/b-catenin signaling
    • He W, Tan R, Dai C et al. Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/b-catenin signaling. J Biol Chem 2010; 285: 24665-24675.
    • (2010) J Biol Chem , vol.285 , pp. 24665-24675
    • He, W.1    Tan, R.2    Dai, C.3
  • 26
    • 47049131867 scopus 로고    scopus 로고
    • Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300
    • Hirota M, Watanabe K, Hamada S et al. Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300. Cell Signal 2008; 20: 1632-1641.
    • (2008) Cell Signal , vol.20 , pp. 1632-1641
    • Hirota, M.1    Watanabe, K.2    Hamada, S.3
  • 27
    • 77949351029 scopus 로고    scopus 로고
    • New insights into epithelial-mesenchymal transition in kidney fibrosis
    • Liu Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 2010; 21: 212-222.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 212-222
    • Liu, Y.1
  • 28
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY et al. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3
  • 29
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119: 1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 30
    • 70349263307 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition as an explanation for podocyte depletion in diabetic nephropathy
    • Yamaguchi Y, Iwano M, Toyoda M et al. Epithelial-mesenchymal transition as an explanation for podocyte depletion in diabetic nephropathy. Am J Kidney Dis 2009; 54: 653-664.
    • (2009) Am J Kidney Dis , vol.54 , pp. 653-664
    • Yamaguchi, Y.1    Iwano, M.2    Toyoda, M.3
  • 31
    • 33751582928 scopus 로고    scopus 로고
    • Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney
    • DOI 10.1038/sj.emboj.7601421, PII 7601421
    • Boutet A, De Frutos CA, Maxwell PH et al. Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J 2006; 25: 5603-5613. (Pubitemid 44847200)
    • (2006) EMBO Journal , vol.25 , Issue.23 , pp. 5603-5613
    • Boutet, A.1    De Frutos, C.A.2    Maxwell, P.H.3    Mayol, M.J.4    Romero, J.5    Nieto, M.A.6
  • 32
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Perez-Moreno MA, Rodrigo I et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 33
    • 68249092353 scopus 로고    scopus 로고
    • A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition
    • Vincent T, Neve EP, Johnson JR et al. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol 2009; 11: 943-950.
    • (2009) Nat Cell Biol , vol.11 , pp. 943-950
    • Vincent, T.1    Neve, E.P.2    Johnson, J.R.3
  • 34
    • 54949102409 scopus 로고    scopus 로고
    • Wnt signaling mediates self-organization and axis formation in embryoid bodies
    • ten Berge D, Koole W, Fuerer C et al. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 2008; 3: 508-518.
    • (2008) Cell Stem Cell , vol.3 , pp. 508-518
    • Ten Berge, D.1    Koole, W.2    Fuerer, C.3
  • 35
    • 33847671000 scopus 로고    scopus 로고
    • Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats
    • DOI 10.1038/labinvest.3700518, PII 3700518
    • Matsui I, Ito T, Kurihara H et al. Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats. Lab Invest 2007; 87: 273-283. (Pubitemid 46353945)
    • (2007) Laboratory Investigation , vol.87 , Issue.3 , pp. 273-283
    • Matsui, I.1    Ito, T.2    Kurihara, H.3    Imai, E.4    Ogihara, T.5    Hori, M.6
  • 36
    • 49349112654 scopus 로고    scopus 로고
    • Wt1 negatively regulates beta-catenin signaling during testis development
    • Chang H, Gao F, Guillou F et al. Wt1 negatively regulates beta-catenin signaling during testis development. Development 2008; 135: 1875-1885.
    • (2008) Development , vol.135 , pp. 1875-1885
    • Chang, H.1    Gao, F.2    Guillou, F.3
  • 37
    • 77951986098 scopus 로고    scopus 로고
    • A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway
    • Kim MS, Yoon SK, Bollig F et al. A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J Biol Chem 2010; 285: 14585-14593.
    • (2010) J Biol Chem , vol.285 , pp. 14585-14593
    • Kim, M.S.1    Yoon, S.K.2    Bollig, F.3
  • 39
    • 0032884884 scopus 로고    scopus 로고
    • β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
    • Brabletz T, Jung A, Dag S et al. beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol 1999; 155: 1033-1038. (Pubitemid 29488909)
    • (1999) American Journal of Pathology , vol.155 , Issue.4 , pp. 1033-1038
    • Brabletz, T.1    Jung, A.2    Dag, S.3    Hlubek, F.4    Kirchner, T.5
  • 41
    • 33750716519 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 in chronic kidney disease: Evidence and mechanisms of action
    • DOI 10.1681/ASN.2006050503
    • Eddy AA, Fogo AB. Plasminogen activator inhibitor-1 in chronic kidney disease: evidence and mechanisms of action. J Am Soc Nephrol 2006; 17: 2999-3012. (Pubitemid 44707760)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.11 , pp. 2999-3012
    • Eddy, A.A.1    Fogo, A.B.2
  • 43
    • 0030670132 scopus 로고    scopus 로고
    • Early role of Fsp1 in epithelialmesenchymal transformation
    • Okada H, Danoff TM, Kalluri R et al. Early role of Fsp1 in epithelialmesenchymal transformation. Am J Physiol 1997; 273: F563-F574.
    • (1997) Am J Physiol , vol.273
    • Okada, H.1    Danoff, T.M.2    Kalluri, R.3
  • 44
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • DOI 10.1038/sj.onc.1210054, PII 1210054
    • Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 2006; 25: 7469-7481. (Pubitemid 44885746)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7469-7481
    • Niehrs, C.1
  • 46
    • 0029824210 scopus 로고    scopus 로고
    • Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells
    • Liu Y, Tolbert EM, Sun AM et al. Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells. Am J Physiol 1996; 271: F679-F688.
    • (1996) Am J Physiol , vol.271
    • Liu, Y.1    Tolbert, E.M.2    Sun, A.M.3
  • 47
    • 77955877135 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria
    • Dai C, Saleem MA, Holzman LB et al. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int 2010; 77: 962-973.
    • (2010) Kidney Int , vol.77 , pp. 962-973
    • Dai, C.1    Saleem, M.A.2    Holzman, L.B.3
  • 48
    • 69849100333 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis
    • Li Y, Tan X, Dai C et al. Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. J Am Soc Nephrol 2009; 20: 1907-1918.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1907-1918
    • Li, Y.1    Tan, X.2    Dai, C.3
  • 49
    • 79952080210 scopus 로고    scopus 로고
    • PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
    • Wang D, Li Y, Wu C et al. PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. PLoS ONE 2011; 6: e17048.
    • (2011) PLoS ONE , vol.6
    • Wang, D.1    Li, Y.2    Wu, C.3


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