메뉴 건너뛰기




Volumn 2016, Issue , 2016, Pages

Therapies for Prevention and Treatment of Alzheimer's Disease

Author keywords

[No Author keywords available]

Indexed keywords

ADUCANUMAB; ALKALOID; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BAN 2401; BAPINEUZUMAB; CHOLINESTERASE INHIBITOR; CLIOQUINOL; CRENEZUMAB; CYCLIN DEPENDENT KINASE 5; ENCENICLINE; EPIGALLOCATECHIN GALLATE; FLAVONOID; GANTENERUMAB; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HOMOTAURINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEUCOMETHYLTHIONINIUM; METHYLENE BLUE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; NOOTROPIC AGENT; PROBIOTIC AGENT; PROTEINASE INHIBITOR; RESVERATROL; SCYLLOINOSITOL; SOLANEZUMAB; TERPENOID; TIDEGLUSIB; UNCLASSIFIED DRUG;

EID: 84982106547     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2016/2589276     Document Type: Review
Times cited : (187)

References (224)
  • 1
    • 84964848239 scopus 로고    scopus 로고
    • The genetic landscape of Alzheimer disease: Clinical implications and perspectives
    • C. Van Cauwenberghe, C. Van Broeckhoven, and K. Sleegers, "The genetic landscape of Alzheimer disease: clinical implications and perspectives, " Genetics in Medicine, vol. 18, no. 5, pp. 421-430, 2015.
    • (2015) Genetics in Medicine , vol.18 , Issue.5 , pp. 421-430
    • Van Cauwenberghe, C.1    Van Broeckhoven, C.2    Sleegers, K.3
  • 2
    • 84937840738 scopus 로고    scopus 로고
    • Metabolic risk factors of sporadic Alzheimer's disease: Implications in the pathology, pathogenesis and treatment
    • S. Chakrabarti, V. K. Khemka, A. Banerjee, G. Chatterjee, A. Ganguly, and A. Biswas, "Metabolic risk factors of sporadic Alzheimer's disease: implications in the pathology, pathogenesis and treatment, " Aging and Disease, vol. 6, no. 4, pp. 282-299, 2015.
    • (2015) Aging and Disease , vol.6 , Issue.4 , pp. 282-299
    • Chakrabarti, S.1    Khemka, V.K.2    Banerjee, A.3    Chatterjee, G.4    Ganguly, A.5    Biswas, A.6
  • 3
    • 79952787104 scopus 로고    scopus 로고
    • Early-onset familial Alzheimer disease
    • R. Pagon, M. Adam, H. Ardinger et al., Eds., University ofWashington, Seattle, Seattle, Wash, USA
    • T. D. Bird, "Early-onset familial Alzheimer disease, " in GeneReviews, R. Pagon, M. Adam, H. Ardinger et al., Eds., pp. 1-42, University ofWashington, Seattle, Seattle, Wash, USA, 2012.
    • (2012) GeneReviews , pp. 1-42
    • Bird, T.D.1
  • 4
    • 84862534228 scopus 로고    scopus 로고
    • Alzheimer's disease: Early diagnosis and treatment
    • L. W. Chu, "Alzheimer's disease: early diagnosis and treatment, " Hong Kong Medical Journal, vol. 18, no. 3, pp. 228-237, 2012.
    • (2012) Hong Kong Medical Journal , vol.18 , Issue.3 , pp. 228-237
    • Chu, L.W.1
  • 5
    • 84944750508 scopus 로고    scopus 로고
    • Amyloid: The key peptide in the pathogenesis of Alzheimer's disease
    • X. Sun, W. Chen, and Y. Wang, "-Amyloid: the key peptide in the pathogenesis of Alzheimer's disease, " Frontiers in Pharmacology, vol. 6, pp. 1-9, 2015.
    • (2015) Frontiers in Pharmacology , vol.6 , pp. 1-9
    • Sun, X.1    Chen, W.2    Wang, Y.3
  • 6
    • 84980019075 scopus 로고    scopus 로고
    • Oxidative challenge in Alzheimer's disease: State of knowledge and future needs
    • C. Cervellati, P. L. Wood, A. Romani et al., "Oxidative challenge in Alzheimer's disease: state of knowledge and future needs, " Journal of Investigative Medicine, vol. 64, no. 1, pp. 21-32, 2016.
    • (2016) Journal of Investigative Medicine , vol.64 , Issue.1 , pp. 21-32
    • Cervellati, C.1    Wood, P.L.2    Romani, A.3
  • 7
    • 84958225958 scopus 로고    scopus 로고
    • Thecellular phase ofAlzheimer's disease
    • B. De Strooper and E. Karran, "Thecellular phase ofAlzheimer's disease, " Cell, vol. 164, no. 4, pp. 603-615, 2016.
    • (2016) Cell , vol.164 , Issue.4 , pp. 603-615
    • De Strooper, B.1    Karran, E.2
  • 8
    • 84866464632 scopus 로고    scopus 로고
    • LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease
    • C. Spuch, S. Ortolano, and C. Navarro, "LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease, " Frontiers in Physiology, vol. 3, article 269, pp. 1-14, 2012.
    • (2012) Frontiers in Physiology , vol.3 , pp. 1-14
    • Spuch, C.1    Ortolano, S.2    Navarro, C.3
  • 9
    • 84947248386 scopus 로고    scopus 로고
    • Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease
    • S. H. Barage andK. D. Sonawane, "Amyloid cascade hypothesis: pathogenesis and therapeutic strategies in Alzheimer's disease, " Neuropeptides, vol. 52, pp. 1-18, 2015.
    • (2015) Neuropeptides , vol.52 , pp. 1-18
    • Barage, S.H.1    Sonawane, K.D.2
  • 10
    • 85006137585 scopus 로고    scopus 로고
    • Tau protein hyperphosphorylation and aggregation in Alzheimer's disease and other tauopathies, and possible neuroprotective strategies
    • G. simíc, M. B. Leko, S. Wray et al., "Tau protein hyperphosphorylation and aggregation in alzheimer's disease and other tauopathies, and possible neuroprotective strategies, " Biomolecules, vol. 6, no. 6, pp. 1-28, 2016.
    • (2016) Biomolecules , vol.6 , Issue.6 , pp. 1-28
    • Simíc, G.1    Leko, M.B.2    Wray, S.3
  • 11
    • 79955738773 scopus 로고    scopus 로고
    • The history of the cholinergic hypothesis
    • A. Contestabile, "The history of the cholinergic hypothesis, " Behavioural Brain Research, vol. 221, no. 2, pp. 334-340, 2011.
    • (2011) Behavioural Brain Research , vol.221 , Issue.2 , pp. 334-340
    • Contestabile, A.1
  • 12
    • 84944441668 scopus 로고    scopus 로고
    • The role of leptin in the sporadic form of Alzheimer's disease. Interactions with the adipokines amylin, ghrelin and the pituitary hormone prolactin
    • J. Folch, I. Patraca, N. Martínez et al., "The role of leptin in the sporadic form of Alzheimer's disease. Interactions with the adipokines amylin, ghrelin and the pituitary hormone prolactin, " Life Sciences, vol. 140, pp. 19-28, 2015.
    • (2015) Life Sciences , vol.140 , pp. 19-28
    • Folch, J.1    Patraca, I.2    Martínez, N.3
  • 13
    • 84947046996 scopus 로고    scopus 로고
    • Vascular dysfunction in the pathogenesis of Alzheimer's disease-A review of endothelium-mediated mechanisms and ensuing vicious circles
    • L. Y. Di Marco, A. Venneri, E. Farkas, P. C. Evans, A. Marzo, and A. F. Frangi, "Vascular dysfunction in the pathogenesis of Alzheimer's disease-a review of endothelium-mediated mechanisms and ensuing vicious circles, " Neurobiology of Disease, vol. 82, pp. 593-606, 2015.
    • (2015) Neurobiology of Disease , vol.82 , pp. 593-606
    • Di Marco, L.Y.1    Venneri, A.2    Farkas, E.3    Evans, P.C.4    Marzo, A.5    Frangi, A.F.6
  • 15
    • 84964886921 scopus 로고    scopus 로고
    • Prediction of progressive mild cognitive impairment by multi-modal neuroimaging biomarkers
    • L. Xu, X. Wu, R. Li et al., "Prediction of progressive mild cognitive impairment by multi-modal neuroimaging biomarkers, " Journal of Alzheimer's Disease, vol. 51, no. 4, pp. 1045-1056, 2016.
    • (2016) Journal of Alzheimer's Disease , vol.51 , Issue.4 , pp. 1045-1056
    • Xu, L.1    Wu, X.2    Li, R.3
  • 17
    • 84936092088 scopus 로고    scopus 로고
    • Menopause, obesity and inflammation: Interactive risk factors for Alzheimer's disease
    • A. Christensen and C. J. Pike, "Menopause, obesity and inflammation: interactive risk factors for Alzheimer's disease, " Frontiers in Aging Neuroscience, vol. 7, article 130, pp. 1-14, 2015.
    • (2015) Frontiers in Aging Neuroscience , vol.7 , pp. 1-14
    • Christensen, A.1    Pike, C.J.2
  • 18
    • 84899895001 scopus 로고    scopus 로고
    • Oxidative stress inAlzheimer's disease
    • Z. Chen andC. Zhong, "Oxidative stress inAlzheimer's disease, " Neuroscience Bulletin, vol. 30, no. 2, pp. 271-281, 2014.
    • (2014) Neuroscience Bulletin , vol.30 , Issue.2 , pp. 271-281
    • Chen, Z.1    Zhong, C.2
  • 20
    • 84909578703 scopus 로고    scopus 로고
    • Neurobiology of Disease Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
    • Y. Huang and R. W. Mahley, "Neurobiology of Disease Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases, " Neurobiology of Disease, vol. 72, pp. 3-12, 2014.
    • (2014) Neurobiology of Disease , vol.72 , pp. 3-12
    • Huang, Y.1    Mahley, R.W.2
  • 22
    • 84905867898 scopus 로고    scopus 로고
    • Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier
    • I. H. K. Dias, M. C. Polidori, and H. R. Griffiths, "Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier, " Biochemical Society Transactions, vol. 42, no. 4, pp. 1001-1005, 2014.
    • (2014) Biochemical Society Transactions , vol.42 , Issue.4 , pp. 1001-1005
    • Dias, I.H.K.1    Polidori, M.C.2    Griffiths, H.R.3
  • 23
    • 84960444400 scopus 로고    scopus 로고
    • Imbalanced cholesterol metabolism in Alzheimer's disease
    • Z. Xue-Shan, W. Qi, R. Zhong et al., "Imbalanced cholesterol metabolism in Alzheimer's disease, " Clinica Chimica Acta, vol. 456, pp. 107-114, 2016.
    • (2016) Clinica Chimica Acta , vol.456 , pp. 107-114
    • Xue-Shan, Z.1    Qi, W.2    Zhong, R.3
  • 24
    • 84949189788 scopus 로고    scopus 로고
    • Inflammation and oxidative stress: The molecular connectivity between insulin resistance, obesity, and Alzheimer's disease
    • G. Verdile, K. N. Keane, V. F. Cruzat et al., "Inflammation and oxidative stress: the molecular connectivity between insulin resistance, obesity, and Alzheimer's disease, " Mediators of Inflammation, vol. 2015, Article ID 105828, 17 pages, 2015.
    • (2015) Mediators of Inflammation , vol.2015
    • Verdile, G.1    Keane, K.N.2    Cruzat, V.F.3
  • 25
    • 84940832096 scopus 로고    scopus 로고
    • Shared neuropathological characteristics of obesity, type 2 diabetes and Alzheimer's disease: Impacts on cognitive decline
    • J. M. Walker and F. E. Harrison, "Shared neuropathological characteristics of obesity, type 2 diabetes and Alzheimer's disease: impacts on cognitive decline, " Nutrients, vol. 7, no. 9, pp. 7332-7357, 2015.
    • (2015) Nutrients , vol.7 , Issue.9 , pp. 7332-7357
    • Walker, J.M.1    Harrison, F.E.2
  • 26
    • 84920861406 scopus 로고    scopus 로고
    • Cardiovascular risk factors and future risk of Alzheimer's disease
    • R. F. de Bruijn and M. A. Ikram, "Cardiovascular risk factors and future risk of Alzheimer's disease, " BMC Medicine, vol. 12, no. 1, article 130, pp. 1-9, 2014.
    • (2014) BMC Medicine , vol.12 , Issue.1 , pp. 1-9
    • De Bruijn, R.F.1    Ikram, M.A.2
  • 27
    • 84904113244 scopus 로고    scopus 로고
    • Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain
    • D. A. Butterfield, F. Di Domenico, and E. Barone, "Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain, " Biochimica et Biophysica Acta-Molecular Basis ofDisease, vol. 1842, no. 9, pp. 1693-1706, 2014.
    • (2014) Biochimica et Biophysica Acta-Molecular Basis OfDisease , vol.1842 , Issue.9 , pp. 1693-1706
    • Butterfield, D.A.1    Di Domenico, F.2    Barone, E.3
  • 28
    • 85047287120 scopus 로고    scopus 로고
    • Molecular and biochemical trajectories from diabetes to Alzheimer's disease?: A critical appraisal
    • R. Sandhir and S. Gupta, "Molecular and biochemical trajectories from diabetes to Alzheimer's disease?: a critical appraisal, " World Journal of Diabetes, vol. 6, no. 12, pp. 1223-1242, 2015.
    • (2015) World Journal of Diabetes , vol.6 , Issue.12 , pp. 1223-1242
    • Sandhir, R.1    Gupta, S.2
  • 30
    • 84863504256 scopus 로고    scopus 로고
    • Apolipoprotein e and apolipoprotein e receptors: Normal biology and roles in Alzheimer disease
    • D. M. Holtzman, J. Herz, and G. Bu, "Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease, " Cold SpringHarbor Perspectives inMedicine, vol. 2, no. 3, Article ID a006312, 2012.
    • (2012) Cold SpringHarbor Perspectives InMedicine , vol.2 , Issue.3
    • Holtzman, D.M.1    Herz, J.2    Bu, G.3
  • 31
    • 84873722367 scopus 로고    scopus 로고
    • Apolipoprotein e and Alzheimer disease: Risk, mechanisms and therapy
    • C.-C. Liu, T. Kanekiyo, H. Xu, and G. Bu, "Apolipoprotein e and Alzheimer disease: risk, mechanisms and therapy, " Nature Reviews Neurology, vol. 9, no. 2, pp. 106-118, 2013.
    • (2013) Nature Reviews Neurology , vol.9 , Issue.2 , pp. 106-118
    • Liu, C.-C.1    Kanekiyo, T.2    Xu, H.3    Bu, G.4
  • 32
    • 2542430828 scopus 로고    scopus 로고
    • ApoE andAbeta1-42 interactions: Effects of isoformand conformation on structure and function
    • A. M. Manelli, W. B. Stine, L. J. Van Eldik, and M. J. LaDu, "ApoE andAbeta1-42 interactions: effects of isoformand conformation on structure and function, " Journal of Molecular Neuroscience, vol. 23, no. 3, pp. 235-246, 2004.
    • (2004) Journal of Molecular Neuroscience , vol.23 , Issue.3 , pp. 235-246
    • Manelli, A.M.1    Stine, W.B.2    Van Eldik, L.J.3    LaDu, M.J.4
  • 33
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
    • E. H. Corder, A. M. Saunders, W. J. Strittmatter et al., "Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families, " Science, vol. 261, no. 5123, pp. 921-923, 1993.
    • (1993) Science , vol.261 , Issue.5123 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 34
    • 84941712337 scopus 로고    scopus 로고
    • Brain amyloid deposition and longitudinal cognitive decline in nondemented older subjects: Results from a multi-ethnic population
    • Y. Gu, Q. R. Razlighi, L. B. Zahodne et al., "Brain amyloid deposition and longitudinal cognitive decline in nondemented older subjects: results from a multi-ethnic population, " PLoS ONE, vol. 116, pp. 1-14, 2015.
    • (2015) PLoS ONE , vol.116 , pp. 1-14
    • Gu, Y.1    Razlighi, Q.R.2    Zahodne, L.B.3
  • 35
    • 77950878145 scopus 로고    scopus 로고
    • Hypometabolism in Alzheimer-affected brain regions in cognitively healthy latino individuals carrying the apolipoprotein e 4 allele
    • J. B. S. Langbaum, K. Chen, R. J. Caselli et al., "Hypometabolism in Alzheimer-affected brain regions in cognitively healthy latino individuals carrying the apolipoprotein E 4 allele, " Archives of Neurology, vol. 67, no. 4, pp. 462-468, 2010.
    • (2010) Archives of Neurology , vol.67 , Issue.4 , pp. 462-468
    • Langbaum, J.B.S.1    Chen, K.2    Caselli, R.J.3
  • 36
    • 84959283514 scopus 로고    scopus 로고
    • Association between CYP17A1 rs3824755 and rs743572 gene polymorphisms and Alzheimer's disease in the Chinese Han population
    • L. Xie, H. Yan, L. Shi et al., "Association between CYP17A1 rs3824755 and rs743572 gene polymorphisms and Alzheimer's disease in the Chinese Han population, " Neuroscience Letters, vol. 618, pp. 77-82, 2016.
    • (2016) Neuroscience Letters , vol.618 , pp. 77-82
    • Xie, L.1    Yan, H.2    Shi, L.3
  • 37
    • 19144373595 scopus 로고    scopus 로고
    • Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City
    • M.-X. Tang, G. Maestre, W.-Y. Tsai et al., "Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City, " The American Journal of Human Genetics, vol. 58, no. 3, pp. 574-584, 1996.
    • (1996) The American Journal of Human Genetics , vol.58 , Issue.3 , pp. 574-584
    • Tang, M.-X.1    Maestre, G.2    Tsai, W.-Y.3
  • 38
    • 0033398004 scopus 로고    scopus 로고
    • Apolipoprotein e (APOE) allele distribution in the world. Is APOE?4 a 'thrifty' allele
    • R. M. Corbo and R. Scacchp, "Apolipoprotein E (APOE) allele distribution in the world. Is APOE?4 a 'thrifty' allele" Annals of Human Genetics, vol. 63, no. 4, pp. 301-310, 1999.
    • (1999) Annals of Human Genetics , vol.63 , Issue.4 , pp. 301-310
    • Corbo, R.M.1    Scacchp, R.2
  • 39
    • 84964865765 scopus 로고    scopus 로고
    • Apolipoprotein 4 is associated with dementia and cognitive impairment predominantly due to Alzheimer's disease and not with vascular cognitive impairment: A Singapore-based cohort
    • Y. L. Chai, H. K.-H. Yeo, J. Wang et al., "Apolipoprotein 4 is associated with dementia and cognitive impairment predominantly due to Alzheimer's disease and not with vascular cognitive impairment: a Singapore-based cohort, " Journal of Alzheimer's Disease, vol. 51, no. 4, pp. 1111-1118, 2016.
    • (2016) Journal of Alzheimer's Disease , vol.51 , Issue.4 , pp. 1111-1118
    • Chai, Y.L.1    Yeo, H.K.-H.2    Wang, J.3
  • 40
    • 84925337089 scopus 로고    scopus 로고
    • Effects of vascular risk factors and APOE 4 on white matter integrity and cognitive decline
    • R. Wang, L. Fratiglioni, E. J. Laukka et al., "Effects of vascular risk factors and APOE 4 on white matter integrity and cognitive decline, " Neurology, vol. 84, no. 11, pp. 1128-1135, 2015.
    • (2015) Neurology , vol.84 , Issue.11 , pp. 1128-1135
    • Wang, R.1    Fratiglioni, L.2    Laukka, E.J.3
  • 41
    • 84920703987 scopus 로고    scopus 로고
    • Alzheimer's disease risk genes andmechanisms of disease pathogenesis
    • C. M. Karch and A. M. Goate, "Alzheimer's disease risk genes andmechanisms of disease pathogenesis, " Biological Psychiatry, vol. 77, no. 1, pp. 43-51, 2015.
    • (2015) Biological Psychiatry , vol.77 , Issue.1 , pp. 43-51
    • Karch, C.M.1    Goate, A.M.2
  • 42
    • 84861525034 scopus 로고    scopus 로고
    • Deferiprone reduces amyloid-and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet
    • J. R. P. Prasanthi, M. Schrag, B. Dasari et al., "Deferiprone reduces amyloid-and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet, " Journal of Alzheimer's Disease, vol. 30, no. 1, pp. 167-182, 2012.
    • (2012) Journal of Alzheimer's Disease , vol.30 , Issue.1 , pp. 167-182
    • Prasanthi, J.R.P.1    Schrag, M.2    Dasari, B.3
  • 43
    • 84864812652 scopus 로고    scopus 로고
    • Effect of western and high fat diets on memory and cholinergic measures in the rat
    • S. Kosari, E. Badoer, J. C. D. Nguyen, A. S. Killcross, and T. A. Jenkins, "Effect of western and high fat diets on memory and cholinergic measures in the rat, " Behavioural Brain Research, vol. 235, no. 1, pp. 98-103, 2012.
    • (2012) Behavioural Brain Research , vol.235 , Issue.1 , pp. 98-103
    • Kosari, S.1    Badoer, E.2    Nguyen, J.C.D.3    Killcross, A.S.4    Jenkins, T.A.5
  • 45
    • 0037490159 scopus 로고    scopus 로고
    • Ceramide stabilizes-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid-peptide biogenesis
    • L. Puglielli, B. C. Ellis, A. J. Saunders, and D. M. Kovacs, "Ceramide stabilizes-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid-peptide biogenesis, " The Journal of Biological Chemistry, vol. 278, no. 22, pp. 19777-19783, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.22 , pp. 19777-19783
    • Puglielli, L.1    Ellis, B.C.2    Saunders, A.J.3    Kovacs, D.M.4
  • 46
    • 79954584874 scopus 로고    scopus 로고
    • Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis
    • C. Marquer, V. Devauges, J.-C. Cossec et al., "Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis, " The FASEB Journal, vol. 25, no. 4, pp. 1295-1305, 2011.
    • (2011) The FASEB Journal , vol.25 , Issue.4 , pp. 1295-1305
    • Marquer, C.1    Devauges, V.2    Cossec, J.-C.3
  • 47
    • 84896731066 scopus 로고    scopus 로고
    • Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts
    • L. K. Cuddy, W. Winick-Ng, and R. J. Rylett, "Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts, " Journal of Neurochemistry, vol. 128, no. 5, pp. 725-740, 2014.
    • (2014) Journal of Neurochemistry , vol.128 , Issue.5 , pp. 725-740
    • Cuddy, L.K.1    Winick-Ng, W.2    Rylett, R.J.3
  • 49
    • 77957959900 scopus 로고    scopus 로고
    • Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits
    • C. Ullrich, M. Pirchl, and C. Humpel, "Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits, "Molecular and Cellular Neuroscience, vol. 45, no. 4, pp. 408-417, 2010.
    • (2010) Molecular and Cellular Neuroscience , vol.45 , Issue.4 , pp. 408-417
    • Ullrich, C.1    Pirchl, M.2    Humpel, C.3
  • 50
    • 84964830250 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis reduces-secretase activity and amyloid-generation
    • Y. Kim, C. Kim, H. Y. Jang, I. Mook-Jung, and B. Kim, "Inhibition of cholesterol biosynthesis reduces-secretase activity and amyloid-generation, " Journal of Alzheimer's Disease, vol. 51, no. 4, pp. 1057-1068, 2016.
    • (2016) Journal of Alzheimer's Disease , vol.51 , Issue.4 , pp. 1057-1068
    • Kim, Y.1    Kim, C.2    Jang, H.Y.3    Mook-Jung, I.4    Kim, B.5
  • 52
    • 84655164281 scopus 로고    scopus 로고
    • Identification and biology of-secretase
    • V. Vingtdeux and P. Marambaud, "Identification and biology of-secretase, " Journal of Neurochemistry, vol. 120, no. 1, pp. 34-45, 2012.
    • (2012) Journal of Neurochemistry , vol.120 , Issue.1 , pp. 34-45
    • Vingtdeux, V.1    Marambaud, P.2
  • 53
    • 84884339335 scopus 로고    scopus 로고
    • Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease
    • J. Popp, S. Meichsner, H. Kölsch et al., "Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease, " Biochemical Pharmacology, vol. 86, no. 1, pp. 37-42, 2013.
    • (2013) Biochemical Pharmacology , vol.86 , Issue.1 , pp. 37-42
    • Popp, J.1    Meichsner, S.2    Kölsch, H.3
  • 54
    • 84903715152 scopus 로고    scopus 로고
    • Apolipoprotein e and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease
    • J. Poirier, J. Miron, C. Picard et al., "Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease, " Neurobiology of Aging, vol. 35, no. 2, pp. S3-S10, 2014.
    • (2014) Neurobiology of Aging , vol.35 , Issue.2 , pp. S3-S10
    • Poirier, J.1    Miron, J.2    Picard, C.3
  • 55
    • 84941313899 scopus 로고    scopus 로고
    • Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap
    • G. Marwarha and O. Ghribi, "Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap" Experimental Gerontology, vol. 68, pp. 13-18, 2015.
    • (2015) Experimental Gerontology , vol.68 , pp. 13-18
    • Marwarha, G.1    Ghribi, O.2
  • 56
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • V. Leoni and C. Caccia, "Oxysterols as biomarkers in neurodegenerative diseases, " Chemistry and Physics of Lipids, vol. 164, no. 6, pp. 515-524, 2011.
    • (2011) Chemistry and Physics of Lipids , vol.164 , Issue.6 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 58
    • 67650753876 scopus 로고    scopus 로고
    • The treatment of hyperhomocysteinemia
    • B. A. Maron and J. Loscalzo, "The treatment of hyperhomocysteinemia, " Annual Review of Medicine, vol. 60, pp. 39-54, 2009.
    • (2009) Annual Review of Medicine , vol.60 , pp. 39-54
    • Maron, B.A.1    Loscalzo, J.2
  • 59
    • 67650484107 scopus 로고    scopus 로고
    • Homocysteine-NMDA receptormediated activation of extracellular signal-regulated kinase leads to neuronal cell death
    • R. Poddar and S. Paul, "Homocysteine-NMDA receptormediated activation of extracellular signal-regulated kinase leads to neuronal cell death, " Journal of Neurochemistry, vol. 110, no. 3, pp. 1095-1106, 2009.
    • (2009) Journal of Neurochemistry , vol.110 , Issue.3 , pp. 1095-1106
    • Poddar, R.1    Paul, S.2
  • 60
    • 79955769953 scopus 로고    scopus 로고
    • Soluble a oligomers inhibit long-termpotentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
    • S. Li, M. Jin, T. Koeglsperger, N. E. Shepardson, G. M. Shankar, and D. J. Selkoe, "Soluble a oligomers inhibit long-termpotentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors, " Journal of Neuroscience, vol. 31, no. 18, pp. 6627-6638, 2011.
    • (2011) Journal of Neuroscience , vol.31 , Issue.18 , pp. 6627-6638
    • Li, S.1    Jin, M.2    Koeglsperger, T.3    Shepardson, N.E.4    Shankar, G.M.5    Selkoe, D.J.6
  • 61
    • 84989915513 scopus 로고    scopus 로고
    • Calcium flux-independent NMDA receptor activity is required for A oligomer-induced synaptic loss
    • J. H. Birnbaum, J. Bali, L. Rajendran, R. M. Nitsch, and C. Tackenberg, "Calcium flux-independent NMDA receptor activity is required for A oligomer-induced synaptic loss, " Cell Death & Disease, vol. 6, no. 6, Article ID e1791, 2015.
    • (2015) Cell Death & Disease , vol.6 , Issue.6
    • Birnbaum, J.H.1    Bali, J.2    Rajendran, L.3    Nitsch, R.M.4    Tackenberg, C.5
  • 62
    • 84959568219 scopus 로고    scopus 로고
    • Hypertension impairs cerebral blood flow in a mouse model for Alzheimer's disease
    • M. Wiesmann, C. Capone, V. Zerbi et al., "Hypertension impairs cerebral blood flow in a mouse model for Alzheimer's disease, " Current Alzheimer Research, vol. 12, no. 10, pp. 914-922, 2015.
    • (2015) Current Alzheimer Research , vol.12 , Issue.10 , pp. 914-922
    • Wiesmann, M.1    Capone, C.2    Zerbi, V.3
  • 63
    • 84858702001 scopus 로고    scopus 로고
    • Blood pressure trajectories from midlife to late life in relation to dementia in women followed for 37 years
    • E. Joas, K. Bäckman, D. Gustafson et al., "Blood pressure trajectories from midlife to late life in relation to dementia in women followed for 37 years, " Hypertension, vol. 59, no. 4, pp. 796-801, 2012.
    • (2012) Hypertension , vol.59 , Issue.4 , pp. 796-801
    • Joas, E.1    Bäckman, K.2    Gustafson, D.3
  • 65
    • 84965156172 scopus 로고    scopus 로고
    • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
    • Y. Lu, F. R. Day, S. Gustafsson et al., "New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk, " Nature Communications, vol. 7, Article ID 10495, 2016.
    • (2016) Nature Communications , vol.7
    • Lu, Y.1    Day, F.R.2    Gustafsson, S.3
  • 66
    • 84964612303 scopus 로고    scopus 로고
    • The risk of overweight/ obesity in mid-life and late life for the development of dementia: A systematic reviewandmeta-analysis of longitudinal studies
    • E. Pedditizi, R. Peters, and N. Beckett, "The risk of overweight/ obesity in mid-life and late life for the development of dementia: a systematic reviewandmeta-analysis of longitudinal studies, " Age and Ageing, vol. 45, no. 1, pp. 14-21, 2016.
    • (2016) Age and Ageing , vol.45 , Issue.1 , pp. 14-21
    • Pedditizi, E.1    Peters, R.2    Beckett, N.3
  • 67
    • 84855459760 scopus 로고    scopus 로고
    • Obesity is associated with hypothalamic injury in rodents and humans
    • J. P. Thaler, C.-X. Yi, E. A. Schur et al., "Obesity is associated with hypothalamic injury in rodents and humans, " The Journal of Clinical Investigation, vol. 122, no. 1, pp. 153-162, 2012.
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.1 , pp. 153-162
    • Thaler, J.P.1    Yi, C.-X.2    Schur, E.A.3
  • 68
    • 84890806968 scopus 로고    scopus 로고
    • Dysregulation of leptin signaling in Alzheimer disease: Evidence for neuronal leptin resistance
    • D. J. Bonda, J. G. Stone, S. L. Torres et al., "Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance, " Journal of Neurochemistry, vol. 128, no. 1, pp. 162-172, 2014.
    • (2014) Journal of Neurochemistry , vol.128 , Issue.1 , pp. 162-172
    • Bonda, D.J.1    Stone, J.G.2    Torres, S.L.3
  • 69
    • 84907920449 scopus 로고    scopus 로고
    • Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function
    • A. Jayaraman, D. Lent-Schochet, and C. J. Pike, "Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function, " Journal of Neuroinflammation, vol. 11, article 162, 2014.
    • (2014) Journal of Neuroinflammation , vol.11
    • Jayaraman, A.1    Lent-Schochet, D.2    Pike, C.J.3
  • 71
    • 84903710625 scopus 로고    scopus 로고
    • Saturated and trans fats and dementia: A systematic review
    • N. D. Barnard, A. E. Bunner, and U. Agarwal, "Saturated and trans fats and dementia: a systematic review, " Neurobiology of Aging, vol. 35, supplement 2, pp. S65-S73, 2014.
    • (2014) Neurobiology of Aging , vol.35 , pp. S65-S73
    • Barnard, N.D.1    Bunner, A.E.2    Agarwal, U.3
  • 72
    • 84903729422 scopus 로고    scopus 로고
    • Dietary fat composition and dementia risk
    • M. C. Morris and C. C. Tangney, "Dietary fat composition and dementia risk, " Neurobiology of Aging, vol. 35, supplement 2, pp. S59-S64, 2014.
    • (2014) Neurobiology of Aging , vol.35 , pp. S59-S64
    • Morris, M.C.1    Tangney, C.C.2
  • 73
    • 84946904993 scopus 로고    scopus 로고
    • High fat diet enhances-site cleavage of amyloid precursor protein (APP) via promoting-site APP cleaving enzyme 1/adaptor protein 2/clathrin complex formation
    • M. Maesako, M. Uemura, Y. Tashiro et al., "High fat diet enhances-site cleavage of amyloid precursor protein (APP) via promoting-site APP cleaving enzyme 1/adaptor protein 2/clathrin complex formation, " PLoS ONE, vol. 10, no. 9, Article ID e0131199, pp. 1-16, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.9 , pp. 1-16
    • Maesako, M.1    Uemura, M.2    Tashiro, Y.3
  • 74
    • 84899898904 scopus 로고    scopus 로고
    • Neurobiology of Aging High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
    • E. M. Knight, I. V. A. Martins, S. Gümüsgöz, S. M. Allan, and C. B. Lawrence, "Neurobiology of Aging High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology, " Neurobiology of Aging, vol. 35, no. 8, pp. 1821-1832, 2014.
    • (2014) Neurobiology of Aging , vol.35 , Issue.8 , pp. 1821-1832
    • Knight, E.M.1    Martins, I.V.A.2    Gümüsgöz, S.3    Allan, S.M.4    Lawrence, C.B.5
  • 75
    • 84930679125 scopus 로고    scopus 로고
    • High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
    • D. Petrov, I. Pedrós, G. Artiach et al., "High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents, " Biochimica et Biophysica Acta- Molecular Basis of Disease, vol. 1852, no. 9, pp. 1687-1699, 2015.
    • (2015) Biochimica et Biophysica Acta- Molecular Basis of Disease , vol.1852 , Issue.9 , pp. 1687-1699
    • Petrov, D.1    Pedrós, I.2    Artiach, G.3
  • 76
    • 62449223532 scopus 로고    scopus 로고
    • Midlife and late-life obesity and the risk of dementia: Cardiovascular health study
    • A. L. Fitzpatrick, L. H. Kuller, O. L. Lopez et al., "Midlife and late-life obesity and the risk of dementia: cardiovascular health study, " Archives of Neurology, vol. 66, no. 3, pp. 336-342, 2009.
    • (2009) Archives of Neurology , vol.66 , Issue.3 , pp. 336-342
    • Fitzpatrick, A.L.1    Kuller, L.H.2    Lopez, O.L.3
  • 78
    • 84929954141 scopus 로고    scopus 로고
    • BMI and risk of dementia in two million people over two decades: A retrospective cohort study
    • N. Qizilbash, J. Gregson, M. E. Johnson et al., "BMI and risk of dementia in two million people over two decades: a retrospective cohort study, " The Lancet Diabetes and Endocrinology, vol. 3, no. 6, pp. 431-436, 2015.
    • (2015) The Lancet Diabetes and Endocrinology , vol.3 , Issue.6 , pp. 431-436
    • Qizilbash, N.1    Gregson, J.2    Johnson, M.E.3
  • 79
    • 85027946037 scopus 로고    scopus 로고
    • Obesity as a risk factor for Alzheimer's disease: The role of adipocytokines
    • L. Letra, I. Santana, and R. Seiça, "Obesity as a risk factor for Alzheimer's disease: the role of adipocytokines, " Metabolic Brain Disease, vol. 29, no. 3, pp. 563-568, 2014.
    • (2014) Metabolic Brain Disease , vol.29 , Issue.3 , pp. 563-568
    • Letra, L.1    Santana, I.2    Seiça, R.3
  • 80
    • 84952885402 scopus 로고    scopus 로고
    • Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease
    • T. L. Platt, T. L. Beckett, K. Kohler, D. M. Niedowicz, and M. P. Murphy, "Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease, " Neuroscience, vol. 315, pp. 162-174, 2016.
    • (2016) Neuroscience , vol.315 , pp. 162-174
    • Platt, T.L.1    Beckett, T.L.2    Kohler, K.3    Niedowicz, D.M.4    Murphy, M.P.5
  • 83
    • 84960869778 scopus 로고    scopus 로고
    • Adipocyte-derived factors in agerelated dementia and their contribution to vascular and Alzheimer pathology
    • M. Ishii and C. Iadecola, "Adipocyte-derived factors in agerelated dementia and their contribution to vascular and Alzheimer pathology, " Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease, vol. 1862, no. 5, pp. 966-974, 2016.
    • (2016) Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease , vol.1862 , Issue.5 , pp. 966-974
    • Ishii, M.1    Iadecola, C.2
  • 84
    • 77649198872 scopus 로고    scopus 로고
    • Leptin-signaling pathways and leptin resistance
    • H. Münzberg, "Leptin-signaling pathways and leptin resistance, " Forum of Nutrition, vol. 63, pp. 123-132, 2010.
    • (2010) Forum of Nutrition , vol.63 , pp. 123-132
    • Münzberg, H.1
  • 85
    • 84960094032 scopus 로고    scopus 로고
    • Peripheral blood adipokines and insulin levels in patients with Alzheimer's disease: A replication study and meta-analysis
    • J. Ma, W. Zhang, H. Wang et al., "Peripheral blood adipokines and insulin levels in patients with Alzheimer's disease: a replication study and meta-analysis, " Current Alzheimer Research, vol. 13, no. 3, pp. 223-233, 2016.
    • (2016) Current Alzheimer Research , vol.13 , Issue.3 , pp. 223-233
    • Ma, J.1    Zhang, W.2    Wang, H.3
  • 86
    • 84872056806 scopus 로고    scopus 로고
    • Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly
    • P. Rajagopalan, A. W. Toga, C. R. Jack, M. W. Weiner, and P. M. Thompson, "Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly, " NeuroReport, vol. 24, no. 2, pp. 58-62, 2013.
    • (2013) NeuroReport , vol.24 , Issue.2 , pp. 58-62
    • Rajagopalan, P.1    Toga, A.W.2    Jack, C.R.3    Weiner, M.W.4    Thompson, P.M.5
  • 88
    • 17844401180 scopus 로고    scopus 로고
    • Molecular and anatomical determinants of central leptin resistance
    • H. Münzberg and M. G. Myers Jr., "Molecular and anatomical determinants of central leptin resistance, " Nature Neuroscience, vol. 8, no. 5, pp. 566-570, 2005.
    • (2005) Nature Neuroscience , vol.8 , Issue.5 , pp. 566-570
    • Münzberg, H.1    Myers, M.G.2
  • 90
    • 84855301511 scopus 로고    scopus 로고
    • Obesity and the ageing brain: Could leptin play a role in neurodegeneration
    • G. H. Doherty, "Obesity and the ageing brain: could leptin play a role in neurodegeneration" Current Gerontology and Geriatrics Research, vol. 2011, Article ID 708154, 8 pages, 2011.
    • (2011) Current Gerontology and Geriatrics Research , vol.2011
    • Doherty, G.H.1
  • 91
    • 84903851215 scopus 로고    scopus 로고
    • Leptin attenuates BACE1 expression and amyloid-genesis via the activation of SIRT1 signaling pathway
    • G. Marwarha, S. Raza, C. Meiers, and O. Ghribi, "Leptin attenuates BACE1 expression and amyloid-genesis via the activation of SIRT1 signaling pathway, " Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, vol. 1842, no. 9, pp. 1587-1595, 2014.
    • (2014) Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease , vol.1842 , Issue.9 , pp. 1587-1595
    • Marwarha, G.1    Raza, S.2    Meiers, C.3    Ghribi, O.4
  • 93
    • 84904580243 scopus 로고    scopus 로고
    • Leptin-induced spine formation requires TrpC channels and the CaM kinase cascade in the hippocampus
    • M. Dhar, G. A. Wayman, M. Zhu, T. J. Lambert, M. A. Davare, and S. M. Appleyard, "Leptin-induced spine formation requires TrpC channels and the CaM kinase cascade in the hippocampus, " The Journal of Neuroscience, vol. 34, no. 30, pp. 10022-10033, 2014.
    • (2014) The Journal of Neuroscience , vol.34 , Issue.30 , pp. 10022-10033
    • Dhar, M.1    Wayman, G.A.2    Zhu, M.3    Lambert, T.J.4    Davare, M.A.5    Appleyard, S.M.6
  • 94
    • 35448972156 scopus 로고    scopus 로고
    • Adiponectin and cardiovascular inflammatory responses
    • Y. Takemura, K. Walsh, and N. Ouchi, "Adiponectin and cardiovascular inflammatory responses, " Current Atherosclerosis Reports, vol. 9, no. 3, pp. 238-243, 2007.
    • (2007) Current Atherosclerosis Reports , vol.9 , Issue.3 , pp. 238-243
    • Takemura, Y.1    Walsh, K.2    Ouchi, N.3
  • 95
    • 84923994435 scopus 로고    scopus 로고
    • From leptin to other adipokines in health and disease: Facts and expectations at the beginning of the 21st century
    • M. Blüher and C. S. Mantzoros, "From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century, " Metabolism: Clinical and Experimental, vol. 64, no. 1, pp. 131-145, 2015.
    • (2015) Metabolism: Clinical and Experimental , vol.64 , Issue.1 , pp. 131-145
    • Blüher, M.1    Mantzoros, C.S.2
  • 96
    • 84966710938 scopus 로고    scopus 로고
    • Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity
    • C. K. Chakraborti, "Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity, " World Journal of Diabetes, vol. 6, no. 15, pp. 1296-1308, 2015.
    • (2015) World Journal of Diabetes , vol.6 , Issue.15 , pp. 1296-1308
    • Chakraborti, C.K.1
  • 97
    • 84871660915 scopus 로고    scopus 로고
    • Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity
    • K.-H. Chan, K. S.-L. Lam, O.-Y. Cheng et al., "Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity, " PLoS ONE, vol. 7, no. 12, Article ID e52354, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.12
    • Chan, K.-H.1    Lam, K.S.-L.2    Cheng, O.-Y.3
  • 98
    • 84955257989 scopus 로고    scopus 로고
    • Alzheimer's like brain changes correlate with low adiponectin plasma levels in type 2 diabetic patients
    • N. García-Casares, J. A. García-Arnés, J. Rioja et al., "Alzheimer's like brain changes correlate with low adiponectin plasma levels in type 2 diabetic patients, " Journal of Diabetes and Its Complications, vol. 30, no. 2, pp. 281-286, 2016.
    • (2016) Journal of Diabetes and Its Complications , vol.30 , Issue.2 , pp. 281-286
    • García-Casares, N.1    García-Arnés, J.A.2    Rioja, J.3
  • 99
    • 84957542331 scopus 로고    scopus 로고
    • The role of human kallikrein 6, clusterin and adiponectin as potential blood biomarkers of dementia
    • L. Dukic, A.-M. Simundic, I. Martinic-Popovic et al., "The role of human kallikrein 6, clusterin and adiponectin as potential blood biomarkers of dementia, " Clinical Biochemistry, vol. 49, no. 3, pp. 213-218, 2016.
    • (2016) Clinical Biochemistry , vol.49 , Issue.3 , pp. 213-218
    • Dukic, L.1    Simundic, A.-M.2    Martinic-Popovic, I.3
  • 100
    • 84881258722 scopus 로고    scopus 로고
    • Gadd153 and NF-B crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and-amyloid production in human neuroblastoma SH-SY5Y cells
    • G. Marwarha, S. Raza, J. R. P. Prasanthi, and O. Ghribi, "Gadd153 and NF-B crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and-amyloid production in human neuroblastoma SH-SY5Y cells, " PLoS ONE, vol. 8, no. 8, Article ID e70773, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.8
    • Marwarha, G.1    Raza, S.2    Prasanthi, J.R.P.3    Ghribi, O.4
  • 101
    • 55049114476 scopus 로고    scopus 로고
    • Tumor necrosis factor-modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures
    • L. Bernardino, F. Agasse, B. Silva, R. Ferreira, S. Grade, and J. O. Malva, "Tumor necrosis factor-modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures, " StemCells, vol. 26, no. 9, pp. 2361-2371, 2008.
    • (2008) StemCells , vol.26 , Issue.9 , pp. 2361-2371
    • Bernardino, L.1    Agasse, F.2    Silva, B.3    Ferreira, R.4    Grade, S.5    Malva, J.O.6
  • 102
    • 84906874007 scopus 로고    scopus 로고
    • Specific antibody binding to the APP672-699 region shifts APP processing from-To-cleavage
    • S. Li, J. Deng, H. Hou et al., "Specific antibody binding to the APP672-699 region shifts APP processing from-To-cleavage, " Cell Death and Disease, vol. 5, no. 8, Article ID e1374, 2014.
    • (2014) Cell Death and Disease , vol.5 , Issue.8
    • Li, S.1    Deng, J.2    Hou, H.3
  • 103
    • 84911893311 scopus 로고    scopus 로고
    • Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis
    • A. Eskilsson, E. Mirrasekhian, S. Dufour, M. Schwaninger, D. Engblom, and A. Blomqvist, "Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis, "TheJournal ofNeuroscience, vol. 34, no. 48, pp. 15957-15961, 2014.
    • (2014) TheJournal OfNeuroscience , vol.34 , Issue.48 , pp. 15957-15961
    • Eskilsson, A.1    Mirrasekhian, E.2    Dufour, S.3    Schwaninger, M.4    Engblom, D.5    Blomqvist, A.6
  • 105
    • 84958124094 scopus 로고    scopus 로고
    • Regulation of cyclic AMP response element-binding protein during neuroglial interactions
    • L. M. Qin, R. Bouchard, and S. Pugazhenthi, "Regulation of cyclic AMP response element-binding protein during neuroglial interactions, " Journal of Neurochemistry, vol. 136, no. 5, pp. 918-930, 2016.
    • (2016) Journal of Neurochemistry , vol.136 , Issue.5 , pp. 918-930
    • Qin, L.M.1    Bouchard, R.2    Pugazhenthi, S.3
  • 106
    • 84873106561 scopus 로고    scopus 로고
    • BDNF and the central control of feeding: Accidental bystander or essential player
    • M. Rios, "BDNF and the central control of feeding: accidental bystander or essential player" Trends in Neurosciences, vol. 36, no. 2, pp. 83-90, 2013.
    • (2013) Trends in Neurosciences , vol.36 , Issue.2 , pp. 83-90
    • Rios, M.1
  • 107
    • 77954947327 scopus 로고    scopus 로고
    • Lower brain-derived neurotrophic factor in patients with Prader-Willi syndrome compared to obese and lean control subjects
    • J. C. Han, M. J. Muehlbauer, H. N. Cui, C. B. Newgard, and A. M. Haqq, "Lower brain-derived neurotrophic factor in patients with Prader-Willi syndrome compared to obese and lean control subjects, " The Journal of Clinical Endocrinology & Metabolism, vol. 95, no. 7, pp. 3532-3536, 2010.
    • (2010) The Journal of Clinical Endocrinology & Metabolism , vol.95 , Issue.7 , pp. 3532-3536
    • Han, J.C.1    Muehlbauer, M.J.2    Cui, H.N.3    Newgard, C.B.4    Haqq, A.M.5
  • 108
    • 84878792450 scopus 로고    scopus 로고
    • Molecular and neural bases underlying roles of BDNF in the control of body weight
    • F. Vanevski and B. Xu, "Molecular and neural bases underlying roles of BDNF in the control of body weight, " Frontiers in Neuroscience, vol. 7, article 37, pp. 1-9, 2013.
    • (2013) Frontiers in Neuroscience , vol.7 , pp. 1-9
    • Vanevski, F.1    Xu, B.2
  • 109
    • 84893021363 scopus 로고    scopus 로고
    • BDNF mediates adaptive brain and body responses to energetic challenges
    • K. Marosi and M. P. Mattson, "BDNF mediates adaptive brain and body responses to energetic challenges, " Trends in Endocrinology and Metabolism, vol. 25, no. 2, pp. 89-98, 2014.
    • (2014) Trends in Endocrinology and Metabolism , vol.25 , Issue.2 , pp. 89-98
    • Marosi, K.1    Mattson, M.P.2
  • 110
    • 77956896591 scopus 로고    scopus 로고
    • Angiotensin II revisited: New roles in inflammation, immunology and aging
    • A. Benigni, P. Cassis, and G. Remuzzi, "Angiotensin II revisited: new roles in inflammation, immunology and aging, " EMBO Molecular Medicine, vol. 2, no. 7, pp. 247-257, 2010.
    • (2010) EMBO Molecular Medicine , vol.2 , Issue.7 , pp. 247-257
    • Benigni, A.1    Cassis, P.2    Remuzzi, G.3
  • 112
    • 84924565894 scopus 로고    scopus 로고
    • Diabetes and Alzheimer disease, two overlapping pathologies with the same background: Oxidative stress
    • S. Rosales-Corral, D.-X. Tan, L. Manchester, and R. J. Reiter, "Diabetes and alzheimer disease, two overlapping pathologies with the same background: oxidative stress, " OxidativeMedicine and Cellular Longevity, vol. 2015, Article ID 985845, 14 pages, 2015.
    • (2015) OxidativeMedicine and Cellular Longevity , vol.2015
    • Rosales-Corral, S.1    Tan, D.-X.2    Manchester, L.3    Reiter, R.J.4
  • 113
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • K. Talbot, H.-Y. Wang, H. Kazi et al., "Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline, "The Journal of Clinical Investigation, vol. 122, no. 4, pp. 1316-1338, 2012.
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.4 , pp. 1316-1338
    • Talbot, K.1    Wang, H.-Y.2    Kazi, H.3
  • 114
    • 77956899143 scopus 로고    scopus 로고
    • Vascular pathology in Alzheimer's disease
    • T. Miyakawa, "Vascular pathology in Alzheimer's disease, " Psychogeriatrics, vol. 10, no. 1, pp. 39-44, 2010.
    • (2010) Psychogeriatrics , vol.10 , Issue.1 , pp. 39-44
    • Miyakawa, T.1
  • 115
    • 78751566697 scopus 로고    scopus 로고
    • Perturbed energy metabolism and neuronal circuit dysfunction in cognitive impairment
    • D. Kapogiannis and M. P. Mattson, "Perturbed energy metabolism and neuronal circuit dysfunction in cognitive impairment, " The Lancet Neurology, vol. 10, no. 2, pp. 187-198, 2011.
    • (2011) The Lancet Neurology , vol.10 , Issue.2 , pp. 187-198
    • Kapogiannis, D.1    Mattson, M.P.2
  • 116
    • 84922514950 scopus 로고    scopus 로고
    • Alzheimer disease and cognitive impairment associated with diabetes mellitus type 2: Associations and a hypothesis
    • R. O. Domínguez, M. A. Pagano, E. R. Marschoff, S. E. González, M. G. Repetto, and J. A. Serra, "Alzheimer disease and cognitive impairment associated with diabetes mellitus type 2: associations and a hypothesis, " Neurologia, vol. 29, no. 9, pp. 567-572, 2014.
    • (2014) Neurologia , vol.29 , Issue.9 , pp. 567-572
    • Domínguez, R.O.1    Pagano, M.A.2    Marschoff, E.R.3    González, S.E.4    Repetto, M.G.5    Serra, J.A.6
  • 117
    • 84920945408 scopus 로고    scopus 로고
    • Cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and Alzheimer's disease: Studies in animal models
    • E. Calvo-Ochoa and C. Arias, "Cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and Alzheimer's disease: studies in animal models, " Diabetes/Metabolism Research and Reviews, vol. 31, no. 1, pp. 1-13, 2015.
    • (2015) Diabetes/Metabolism Research and Reviews , vol.31 , Issue.1 , pp. 1-13
    • Calvo-Ochoa, E.1    Arias, C.2
  • 119
    • 84942100980 scopus 로고    scopus 로고
    • Insulin resistance as commonmolecular denominator linking obesity to Alzheimer's disease
    • D. Nuzzo, P. Picone, S. Baldassano et al., "Insulin resistance as commonmolecular denominator linking obesity to Alzheimer's disease, " Current Alzheimer Research, vol. 12, no. 8, pp. 723-735, 2015.
    • (2015) Current Alzheimer Research , vol.12 , Issue.8 , pp. 723-735
    • Nuzzo, D.1    Picone, P.2    Baldassano, S.3
  • 120
    • 84941092027 scopus 로고    scopus 로고
    • Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice
    • E. S. Chan, C. Chen, G. M. Cole, and B.-S. Wong, "Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice, " Scientific Reports, vol. 5, Article ID 13842, 2015.
    • (2015) Scientific Reports , vol.5
    • Chan, E.S.1    Chen, C.2    Cole, G.M.3    Wong, B.-S.4
  • 121
    • 84914689236 scopus 로고    scopus 로고
    • The microbiome and disease: Reviewing the links between the oral microbiome, aging, and Alzheimer's disease
    • D. K. Shoemark and S. J. Allen, "The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease, " Journal of Alzheimer's Disease, vol. 43, no. 3, pp. 725-738, 2015.
    • (2015) Journal of Alzheimer's Disease , vol.43 , Issue.3 , pp. 725-738
    • Shoemark, D.K.1    Allen, S.J.2
  • 122
    • 84867074831 scopus 로고    scopus 로고
    • Ametagenome-wide association study of gut microbiota in type-2 diabetes
    • J. Qin, Y. Li, Z. Cai et al., "Ametagenome-wide association study of gut microbiota in type-2 diabetes, " Nature, vol. 490, pp. 55-60, 2012.
    • (2012) Nature , vol.490 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3
  • 123
    • 85050577489 scopus 로고    scopus 로고
    • Can microbiota research change our understanding of neurodegenerative diseases
    • F. Scheperjan, "Can microbiota research change our understanding of neurodegenerative diseases" Neurodegenerative Disease Management, vol. 6, no. 2, pp. 81-85, 2016.
    • (2016) Neurodegenerative Disease Management , vol.6 , Issue.2 , pp. 81-85
    • Scheperjan, F.1
  • 124
    • 84914689165 scopus 로고    scopus 로고
    • Bacterial infection and Alzheimer's disease: A meta-analysis
    • P. Maheshwari and G. D. Eslick, "Bacterial infection and Alzheimer's disease: a meta-analysis, " Journal of Alzheimer's Disease, vol. 43, no. 3, pp. 957-966, 2015.
    • (2015) Journal of Alzheimer's Disease , vol.43 , Issue.3 , pp. 957-966
    • Maheshwari, P.1    Eslick, G.D.2
  • 125
    • 84890539671 scopus 로고    scopus 로고
    • Titers of herpes simplex virus type 1 antibodies positively correlate with grey matter volumes in Alzheimer's disease
    • R. Mancuso, F. Baglio, M. Cabinio et al., "Titers of herpes simplex virus type 1 antibodies positively correlate with grey matter volumes in Alzheimer's disease, " Journal of Alzheimer's Disease, vol. 38, no. 4, pp. 741-745, 2014.
    • (2014) Journal of Alzheimer's Disease , vol.38 , Issue.4 , pp. 741-745
    • Mancuso, R.1    Baglio, F.2    Cabinio, M.3
  • 126
    • 84925348854 scopus 로고    scopus 로고
    • Mechanisms of molecular mimicry involving the microbiota in neurodegeneration
    • R. P. Friedland, "Mechanisms of molecular mimicry involving the microbiota in neurodegeneration, " Journal of Alzheimer's Disease, vol. 45, no. 2, pp. 349-362, 2015.
    • (2015) Journal of Alzheimer's Disease , vol.45 , Issue.2 , pp. 349-362
    • Friedland, R.P.1
  • 127
    • 84888394934 scopus 로고    scopus 로고
    • Inflammation and-synuclein's prion-like behavior in Parkinson's disease-is there a link
    • C. M. Lema Tomé, T. Tyson, N. L. Rey, S. Grathwohl, M. Britschgi, and P. Brundin, "Inflammation and-synuclein's prion-like behavior in Parkinson's disease-is there a link" Molecular neurobiology, vol. 47, no. 2, pp. 561-574, 2013.
    • (2013) Molecular Neurobiology , vol.47 , Issue.2 , pp. 561-574
    • Lema Tomé, C.M.1    Tyson, T.2    Rey, N.L.3    Grathwohl, S.4    Britschgi, M.5    Brundin, P.6
  • 128
    • 84904039648 scopus 로고    scopus 로고
    • Understanding gut microbiota in elderly's health will enable intervention through probiotics
    • G. PérezMartínez, C. Bäuerl, and M. C. Collado, "Understanding gut microbiota in elderly's health will enable intervention through probiotics, " Beneficial Microbes, vol. 5, no. 3, pp. 235-246, 2014.
    • (2014) Beneficial Microbes , vol.5 , Issue.3 , pp. 235-246
    • PérezMartínez, G.1    Bäuerl, C.2    Collado, M.C.3
  • 130
    • 71749104020 scopus 로고    scopus 로고
    • TNF-and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects
    • A. R. Kamer, R. G. Craig, E. Pirraglia et al., "TNF-and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects, " Journal of Neuroimmunology, vol. 216, no. 1-2, pp. 92-97, 2009.
    • (2009) Journal of Neuroimmunology , vol.216 , Issue.1-2 , pp. 92-97
    • Kamer, A.R.1    Craig, R.G.2    Pirraglia, E.3
  • 131
    • 84958772667 scopus 로고    scopus 로고
    • Current and novel therapeutic molecules and targets in Alzheimer's disease
    • A. Kumar, C. M. Nisha, C. Silakari et al., "Current and novel therapeutic molecules and targets in Alzheimer's disease, " Journal of the Formosan Medical Association, vol. 115, no. 1, pp. 3-10, 2016.
    • (2016) Journal of the Formosan Medical Association , vol.115 , Issue.1 , pp. 3-10
    • Kumar, A.1    Nisha, C.M.2    Silakari, C.3
  • 133
    • 84941170373 scopus 로고    scopus 로고
    • Slowing the progression of Alzheimer's disease; What works
    • L. Nelson andN. Tabet, "Slowing the progression of Alzheimer's disease; what works" Ageing Research Reviews, vol. 23, pp. 193-209, 2015.
    • (2015) Ageing Research Reviews , vol.23 , pp. 193-209
    • Nelson, L.1    Tabet, N.2
  • 134
    • 84887649697 scopus 로고    scopus 로고
    • Acholinergic trigger drives learning-induced plasticity at hippocampal synapses
    • D. Mitsushima, A. Sano, and T. Takahashi, "Acholinergic trigger drives learning-induced plasticity at hippocampal synapses, " Nature Communications, vol. 4, article 2760, 2013.
    • (2013) Nature Communications , vol.4
    • Mitsushima, D.1    Sano, A.2    Takahashi, T.3
  • 135
    • 84940933988 scopus 로고    scopus 로고
    • The keystone of Alzheimer pathogenesis might be sought in A physiology
    • D. Puzzo, W. Gulisano, O. Arancio, and A. Palmeri, "The keystone of Alzheimer pathogenesis might be sought in A physiology, " Neuroscience, vol. 307, pp. 26-36, 2015.
    • (2015) Neuroscience , vol.307 , pp. 26-36
    • Puzzo, D.1    Gulisano, W.2    Arancio, O.3    Palmeri, A.4
  • 136
    • 63449094785 scopus 로고    scopus 로고
    • Amyloid beta mediates memory formation
    • A. Garcia-Osta and C. M. Alberini, "Amyloid beta mediates memory formation, " Learning and Memory, vol. 16, no. 4, pp. 267-272, 2009.
    • (2009) Learning and Memory , vol.16 , Issue.4 , pp. 267-272
    • Garcia-Osta, A.1    Alberini, C.M.2
  • 137
    • 84877873373 scopus 로고    scopus 로고
    • A review on cholinesterase inhibitors forAlzheimer's disease
    • P. Anand and B. Singh, "A review on cholinesterase inhibitors forAlzheimer's disease, "Archives of Pharmacal Research, vol. 36, no. 4, pp. 375-399, 2013.
    • (2013) Archives of Pharmacal Research , vol.36 , Issue.4 , pp. 375-399
    • Anand, P.1    Singh, B.2
  • 138
    • 84939567406 scopus 로고    scopus 로고
    • Prevention of sporadic Alzheimer's disease: Lessons learned fromclinical trials and future directions
    • S. Andrieu, N. Coley, S. Lovestone, P. S. Aisen, and B. Vellas, "Prevention of sporadic Alzheimer's disease: lessons learned fromclinical trials and future directions, " The Lancet Neurology, vol. 14, no. 9, pp. 926-944, 2015.
    • (2015) The Lancet Neurology , vol.14 , Issue.9 , pp. 926-944
    • Andrieu, S.1    Coley, N.2    Lovestone, S.3    Aisen, P.S.4    Vellas, B.5
  • 139
    • 84953868005 scopus 로고    scopus 로고
    • Therapeutic strategies for Alzheimer's disease in clinical trials
    • J. Godýn, J. Jónczyk, D. Panek, and B. Malawska, "Therapeutic strategies for Alzheimer's disease in clinical trials, " Pharmacological Reports, vol. 68, no. 1, pp. 127-138, 2016.
    • (2016) Pharmacological Reports , vol.68 , Issue.1 , pp. 127-138
    • Godýn, J.1    Jónczyk, J.2    Panek, D.3    Malawska, B.4
  • 140
    • 84955605711 scopus 로고    scopus 로고
    • Current research therapeutic strategies for Alzheimer's disease treatment
    • J. Folch, D. Petrov, M. Ettcheto et al., "Current research therapeutic strategies for Alzheimer's disease treatment, " Neural Plasticity, vol. 2016, Article ID 8501693, 15 pages, 2016.
    • (2016) Neural Plasticity , vol.2016
    • Folch, J.1    Petrov, D.2    Ettcheto, M.3
  • 141
    • 84947080447 scopus 로고    scopus 로고
    • Mechanisms of neuronal protection against excitotoxicity, endoplasmic reticulum stress, and mitochondrial dysfunction in stroke and neurodegenerative diseases
    • H. Prentice, J. P. Modi, and J.-Y. Wu, "Mechanisms of neuronal protection against excitotoxicity, endoplasmic reticulum stress, and mitochondrial dysfunction in stroke and neurodegenerative diseases, " Oxidative Medicine and Cellular Longevity, vol. 2015, Article ID 964518, 7 pages, 2015.
    • (2015) Oxidative Medicine and Cellular Longevity , vol.2015
    • Prentice, H.1    Modi, J.P.2    Wu, J.-Y.3
  • 143
    • 84956923325 scopus 로고    scopus 로고
    • Memantine attenuatesAlzheimer's disease-like pathology and cognitive impairment
    • X. Wang, J. Blanchard, I. Grundke-Iqbal, and K. Iqbal, "Memantine attenuatesAlzheimer's disease-like pathology and cognitive impairment, " PLoSONE, vol. 10, no. 12, Article ID0145441, 2015.
    • (2015) PLoSONE , vol.10 , Issue.12
    • Wang, X.1    Blanchard, J.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 144
    • 84930654688 scopus 로고    scopus 로고
    • The maze of APP processing in Alzheimer's disease: Where did we go wrong in reasoning
    • M. Chen, "The maze of APP processing in Alzheimer's disease: where did we go wrong in reasoning" Frontiers in Cellular Neuroscience, vol. 9, article 186, pp. 1-10, 2015.
    • (2015) Frontiers in Cellular Neuroscience , vol.9 , pp. 1-10
    • Chen, M.1
  • 146
    • 84922771460 scopus 로고    scopus 로고
    • Melatonin stimulates the nonamyloidogenic processing of aPP through the positive transcriptional regulation of ADAM10 and ADAM17
    • M. Shukla, H. H. Htoo, P. Wintachai et al., "Melatonin stimulates the nonamyloidogenic processing of aPP through the positive transcriptional regulation of ADAM10 and ADAM17, " Journal of Pineal Research, vol. 58, no. 2, pp. 151-165, 2015.
    • (2015) Journal of Pineal Research , vol.58 , Issue.2 , pp. 151-165
    • Shukla, M.1    Htoo, H.H.2    Wintachai, P.3
  • 147
    • 84907026866 scopus 로고    scopus 로고
    • Regulation of amyloid precursor protein processing by serotonin signaling
    • A. A. Pimenova, A. Thathiah, B. De Strooper, and I. Tesseur, "Regulation of amyloid precursor protein processing by serotonin signaling, " PLoSONE, vol. 9, no. 1, Article IDe87014, 2014.
    • (2014) PLoSONE , vol.9 , Issue.1
    • Pimenova, A.A.1    Thathiah, A.2    De Strooper, B.3    Tesseur, I.4
  • 148
    • 84904561671 scopus 로고    scopus 로고
    • Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFADmice
    • A. Fragkouli, E. C. Tsilibary, and A. K. Tzinia, "Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFADmice, " Neurobiology of Disease, vol. 70, pp. 179-189, 2014.
    • (2014) Neurobiology of Disease , vol.70 , pp. 179-189
    • Fragkouli, A.1    Tsilibary, E.C.2    Tzinia, A.K.3
  • 149
    • 84904557569 scopus 로고    scopus 로고
    • Secretase inhibitor; A promising novel therapeutic drug in Alzheimer's disease
    • K. W. Menting and J. A. H. R. Claassen, "-Secretase inhibitor; a promising novel therapeutic drug in Alzheimer's disease, " Frontiers in Aging Neuroscience, vol. 6, article 165, 2014.
    • (2014) Frontiers in Aging Neuroscience , vol.6
    • Menting, K.W.1    Claassen, J.A.H.R.2
  • 150
    • 84952890063 scopus 로고    scopus 로고
    • Betaamyloid and Tau-protein: Structure, interaction, and prion-like properties
    • O. G. Tatarnikova, M. A. Orlov, and N. V. Bobkova, "Betaamyloid and Tau-protein: structure, interaction, and prion-like properties, " Biochemistry, vol. 80, no. 13, pp. 1800-1819, 2015.
    • (2015) Biochemistry , vol.80 , Issue.13 , pp. 1800-1819
    • Tatarnikova, O.G.1    Orlov, M.A.2    Bobkova, N.V.3
  • 151
    • 84923590684 scopus 로고    scopus 로고
    • A-secretase inhibitor, but not a-secretase modulator, induced defects in BDNF axonal trafficking and signaling: Evidence for a role for APP
    • A. M. Weissmiller, O. Natera-Naranjo, S. M. Reyna et al., "A-secretase inhibitor, but not a-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP, " PLoS ONE, vol. 10, no. 2, Article ID e0118379, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.2
    • Weissmiller, A.M.1    Natera-Naranjo, O.2    Reyna, S.M.3
  • 152
    • 84864392474 scopus 로고    scopus 로고
    • Contribution of the-secretase subunits to the formation of catalytic pore of presenilin 1 protein
    • K. Takeo, N. Watanabe, T. Tomita, and T. Iwatsubo, "Contribution of the-secretase subunits to the formation of catalytic pore of presenilin 1 protein, "TheJournal of Biological Chemistry, vol. 287, no. 31, pp. 25834-25843, 2012.
    • (2012) TheJournal of Biological Chemistry , vol.287 , Issue.31 , pp. 25834-25843
    • Takeo, K.1    Watanabe, N.2    Tomita, T.3    Iwatsubo, T.4
  • 154
    • 84937197237 scopus 로고    scopus 로고
    • Cholestenoic acid, an endogenous cholesterol metabolite, is a potent-secretase modulator
    • J. I. Jung, A. R. Price, T. B. Ladd et al., "Cholestenoic acid, an endogenous cholesterol metabolite, is a potent-secretase modulator, " Molecular Neurodegeneration, vol. 10, article 29, 2015.
    • (2015) Molecular Neurodegeneration , vol.10
    • Jung, J.I.1    Price, A.R.2    Ladd, T.B.3
  • 155
    • 84959010623 scopus 로고    scopus 로고
    • Alzheimer's disease: An overview of amyloid beta dependent pathogenesis and its therapeutic implications along with in silico approaches emphasizing the role of natural products
    • M. Awasthi, S. Singh, V. P. Pandey, and U. N. Dwivedi, "Alzheimer's disease: an overview of amyloid beta dependent pathogenesis and its therapeutic implications along with in silico approaches emphasizing the role of natural products, " Journal of the Neurological Sciences, vol. 361, pp. 256-271, 2016.
    • (2016) Journal of the Neurological Sciences , vol.361 , pp. 256-271
    • Awasthi, M.1    Singh, S.2    Pandey, V.P.3    Dwivedi, U.N.4
  • 156
    • 84938630567 scopus 로고    scopus 로고
    • Reducing A load and tau phosphorylation: Emerging perspective for treating Alzheimer's disease
    • J. Kalra and A. Khan, "Reducing A load and tau phosphorylation: emerging perspective for treating Alzheimer's disease, " European Journal of Pharmacology, vol. 764, pp. 571-581, 2015.
    • (2015) European Journal of Pharmacology , vol.764 , pp. 571-581
    • Kalra, J.1    Khan, A.2
  • 157
    • 84925619359 scopus 로고    scopus 로고
    • Sheet interfering molecules acting against-amyloid aggregation and fibrillogenesis
    • A. Francioso, P. Punzi, A. Boffi et al., "-Sheet interfering molecules acting against-amyloid aggregation and fibrillogenesis, " Bioorganic and Medicinal Chemistry, vol. 23, no. 8, pp. 1671-1683, 2015.
    • (2015) Bioorganic and Medicinal Chemistry , vol.23 , Issue.8 , pp. 1671-1683
    • Francioso, A.1    Punzi, P.2    Boffi, A.3
  • 158
    • 79952489024 scopus 로고    scopus 로고
    • Therapeutic efficacy of stemazole in a beta-amyloid injection rat model of Alzheimer's disease
    • M. Han, Y. Liu, Q. Tan et al., "Therapeutic efficacy of stemazole in a beta-amyloid injection rat model of Alzheimer's disease, " European Journal of Pharmacology, vol. 657, no. 1-3, pp. 104-110, 2011.
    • (2011) European Journal of Pharmacology , vol.657 , Issue.1-3 , pp. 104-110
    • Han, M.1    Liu, Y.2    Tan, Q.3
  • 159
    • 84902953435 scopus 로고    scopus 로고
    • Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity
    • C. Stack, S. Jainuddin, C. Elipenahli et al., "Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity, " Human Molecular Genetics, vol. 23, no. 14, Article ID ddu080, pp. 3716-3732, 2014.
    • (2014) Human Molecular Genetics , vol.23 , Issue.14 , pp. 3716-3732
    • Stack, C.1    Jainuddin, S.2    Elipenahli, C.3
  • 160
    • 84928393250 scopus 로고    scopus 로고
    • Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models
    • V. Melis, M. Magbagbeolu, J. E. Rickard et al., "Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models, " Behavioural Pharmacology, vol. 26, no. 4, pp. 353-368, 2015.
    • (2015) Behavioural Pharmacology , vol.26 , Issue.4 , pp. 353-368
    • Melis, V.1    Magbagbeolu, M.2    Rickard, J.E.3
  • 162
    • 84951926026 scopus 로고    scopus 로고
    • LDL-lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells: Mitigation by statin intervention
    • H. K. I. Dias, C. L. R. Brown, M. C. Polidori, G. Y. H. Lip, and H. R. Griffiths, "LDL-lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells: mitigation by statin intervention, " Clinical Science, vol. 129, no. 12, pp. 1195-1206, 2016.
    • (2016) Clinical Science , vol.129 , Issue.12 , pp. 1195-1206
    • Dias, H.K.I.1    Brown, C.L.R.2    Polidori, M.C.3    Lip, G.Y.H.4    Griffiths, H.R.5
  • 163
    • 84983514598 scopus 로고    scopus 로고
    • Early statin use and the progression of Alzheimer disease: A total population-based case-control study
    • F. C. Lin, Y. S. Chuang, H. M. Hsieh et al., "Early statin use and the progression of Alzheimer disease: a total population-based case-control study, " Medicine, vol. 94, no. 47, Article ID e2143, 2015.
    • (2015) Medicine , vol.94 , Issue.47
    • Lin, F.C.1    Chuang, Y.S.2    Hsieh, H.M.3
  • 164
    • 84949257250 scopus 로고    scopus 로고
    • Metabolic syndrome update
    • S. M. Grundy, "Metabolic syndrome update, " Trends in Cardiovascular Medicine, vol. 26, no. 4, pp. 364-373, 2016.
    • (2016) Trends in Cardiovascular Medicine , vol.26 , Issue.4 , pp. 364-373
    • Grundy, S.M.1
  • 165
    • 84953212495 scopus 로고    scopus 로고
    • Systematic review ofmetabolic syndrome biomarkers: A panel for early detection, management, and risk stratification in theWestVirginian population
    • K. Srikanthan, A. Feyh, H. Visweshwar, J. I. Shapiro, and K. Sodhi, "Systematic review ofmetabolic syndrome biomarkers: a panel for early detection, management, and risk stratification in theWestVirginian population, " International Journal ofMedical Sciences, vol. 13, no. 1, pp. 25-38, 2016.
    • (2016) International Journal OfMedical Sciences , vol.13 , Issue.1 , pp. 25-38
    • Srikanthan, K.1    Feyh, A.2    Visweshwar, H.3    Shapiro, J.I.4    Sodhi, K.5
  • 167
    • 84946032343 scopus 로고    scopus 로고
    • Effect of cholesterol reduction on receptor signaling in neurons
    • K. Fukui, H. A. Ferris, and C. R. Kahn, "Effect of cholesterol reduction on receptor signaling in neurons, " The Journal of Biological Chemistry, vol. 290, no. 44, pp. 26383-26392, 2015.
    • (2015) The Journal of Biological Chemistry , vol.290 , Issue.44 , pp. 26383-26392
    • Fukui, K.1    Ferris, H.A.2    Kahn, C.R.3
  • 168
    • 84959018825 scopus 로고    scopus 로고
    • Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies
    • V. Rani, G. Deep, R. K. Singh, K. Palle, and U. C. S. Yadav, "Oxidative stress and metabolic disorders: pathogenesis and therapeutic strategies, " Life Sciences, vol. 148, no. 11, pp. 183-193, 2016.
    • (2016) Life Sciences , vol.148 , Issue.11 , pp. 183-193
    • Rani, V.1    Deep, G.2    Singh, R.K.3    Palle, K.4    Yadav, U.C.S.5
  • 169
    • 84926354826 scopus 로고    scopus 로고
    • Treatment for Alzheimer's disease: Has anything changed
    • L. M. Waite, "Treatment for Alzheimer's disease: has anything changed" Australian Prescriber, vol. 38, no. 2, pp. 60-63, 2015.
    • (2015) Australian Prescriber , vol.38 , Issue.2 , pp. 60-63
    • Waite, L.M.1
  • 170
    • 84906667101 scopus 로고    scopus 로고
    • The impact of exercise, cognitive activities, and socialization on cognitive function: Results from the national long-termcare survey
    • M. K. Jedrziewski, D. C. Ewbank, H. Wang, and J. Q. Trojanowski, "The impact of exercise, cognitive activities, and socialization on cognitive function: results from the national long-termcare survey, " American Journal of Alzheimer's Disease &OtherDementias, vol. 29, no. 4, pp. 372-378, 2014.
    • (2014) American Journal of Alzheimer's Disease &OtherDementias , vol.29 , Issue.4 , pp. 372-378
    • Jedrziewski, M.K.1    Ewbank, D.C.2    Wang, H.3    Trojanowski, J.Q.4
  • 171
    • 84917700026 scopus 로고    scopus 로고
    • Physical activity attenuates age-related biomarker alterations in preclinical AD
    • O. C. Okonkwo, S. A. Schultz, J. M. Oh et al., "Physical activity attenuates age-related biomarker alterations in preclinical AD, " Neurology, vol. 83, no. 19, pp. 1753-1760, 2014.
    • (2014) Neurology , vol.83 , Issue.19 , pp. 1753-1760
    • Okonkwo, O.C.1    Schultz, S.A.2    Oh, J.M.3
  • 172
    • 0038130715 scopus 로고    scopus 로고
    • Leisure activities and the risk of dementia in the elderly
    • J. Verghese, R. B. Lipton, M. J. Katz et al., "Leisure activities and the risk of dementia in the elderly, "The New England Journal of Medicine, vol. 348, no. 25, pp. 2508-2516, 2003.
    • (2003) The New England Journal of Medicine , vol.348 , Issue.25 , pp. 2508-2516
    • Verghese, J.1    Lipton, R.B.2    Katz, M.J.3
  • 173
    • 84945546892 scopus 로고    scopus 로고
    • Effects of treadmill exercise on hippocampal neurogenesis in an MPTP /probenecid-induced Parkinson's disease mouse model
    • Y.-H. Sung, "Effects of treadmill exercise on hippocampal neurogenesis in an MPTP /probenecid-induced Parkinson's disease mouse model, " Journal of Physical Therapy Science, vol. 27, no. 10, pp. 3203-3206, 2015.
    • (2015) Journal of Physical Therapy Science , vol.27 , Issue.10 , pp. 3203-3206
    • Sung, Y.-H.1
  • 174
    • 84959431965 scopus 로고    scopus 로고
    • Physical exercise increases adult hippocampal neurogenesis inmale rats provided it is aerobic and sustained
    • M. S. Nokia, S. Lensu, J. P. Ahtiainen et al., "Physical exercise increases adult hippocampal neurogenesis inmale rats provided it is aerobic and sustained, " The Journal of Physiology, vol. 594, no. 7, pp. 1855-1873, 2016.
    • (2016) The Journal of Physiology , vol.594 , Issue.7 , pp. 1855-1873
    • Nokia, M.S.1    Lensu, S.2    Ahtiainen, J.P.3
  • 175
    • 84872200865 scopus 로고    scopus 로고
    • Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats
    • R. B. Speisman, A. Kumar, A. Rani, T. C. Foster, and B. K. Ormerod, "Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats, " Brain, Behavior, and Immunity, vol. 28, pp. 25-43, 2013.
    • (2013) Brain, Behavior, and Immunity , vol.28 , pp. 25-43
    • Speisman, R.B.1    Kumar, A.2    Rani, A.3    Foster, T.C.4    Ormerod, B.K.5
  • 176
    • 84937043295 scopus 로고    scopus 로고
    • Protective effects of physical exercise in Alzheimer's disease and Parkinson's disease: A narrative review
    • T. Paillard, Y. Rolland, and P. S. de Barreto, "Protective effects of physical exercise in Alzheimer's disease and Parkinson's disease: a narrative review, " Journal of Clinical Neurology, vol. 11, no. 3, pp. 212-219, 2015.
    • (2015) Journal of Clinical Neurology , vol.11 , Issue.3 , pp. 212-219
    • Paillard, T.1    Rolland, Y.2    De Barreto, P.S.3
  • 177
    • 80053569697 scopus 로고    scopus 로고
    • Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable
    • P. Bekinschtein, C. A. Oomen, L. M. Saksida, and T. J. Bussey, "Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable" Seminars in Cell & Developmental Biology, vol. 22, no. 5, pp. 536-542, 2011.
    • (2011) Seminars in Cell & Developmental Biology , vol.22 , Issue.5 , pp. 536-542
    • Bekinschtein, P.1    Oomen, C.A.2    Saksida, L.M.3    Bussey, T.J.4
  • 178
    • 84923347203 scopus 로고    scopus 로고
    • Lifelong brain health is a lifelong challenge. from evolutionary principles to empirical evidence
    • M. P. Mattson, "Lifelong brain health is a lifelong challenge. From evolutionary principles to empirical evidence, " Ageing Research Reviews, vol. 20, pp. 37-45, 2015.
    • (2015) Ageing Research Reviews , vol.20 , pp. 37-45
    • Mattson, M.P.1
  • 179
    • 84923480043 scopus 로고    scopus 로고
    • Reduction of-amyloid and-secretase by calorie restriction in female Tg2576 mice
    • M. J. Schafer, M. J. Alldred, S. H. Lee et al., "Reduction of-amyloid and-secretase by calorie restriction in female Tg2576 mice, " Neurobiology of Aging, vol. 36, no. 3, pp. 1293-1302, 2015.
    • (2015) Neurobiology of Aging , vol.36 , Issue.3 , pp. 1293-1302
    • Schafer, M.J.1    Alldred, M.J.2    Lee, S.H.3
  • 180
    • 2442566380 scopus 로고    scopus 로고
    • An active and socially integrated lifestyle in late life might protect against dementia
    • L. Fratiglioni, S. Paillard-Borg, and B. Winblad, "An active and socially integrated lifestyle in late life might protect against dementia, " The Lancet Neurology, vol. 3, no. 6, pp. 343-353, 2004.
    • (2004) The Lancet Neurology , vol.3 , Issue.6 , pp. 343-353
    • Fratiglioni, L.1    Paillard-Borg, S.2    Winblad, B.3
  • 182
    • 84884177468 scopus 로고    scopus 로고
    • Exercise training plus calorie restriction causes synergistic protection against cognitive decline via up-regulation of BDNF in hippocampus of stroke-prone hypertensive rats
    • San Diego, Calif, USA, August
    • T. Kishi andK. Sunagawa, "Exercise training plus calorie restriction causes synergistic protection against cognitive decline via up-regulation of BDNF in hippocampus of stroke-prone hypertensive rats, " in Proceedings of the 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS '12), pp. 6764-6767, San Diego, Calif, USA, August 2012.
    • (2012) Proceedings of the 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS '12) , pp. 6764-6767
    • Kishi, T.1    Sunagawa, K.2
  • 183
    • 84961116833 scopus 로고    scopus 로고
    • Sirtuins, cell senescence, and vascular aging
    • Y. Kida and M. S. Goligorsky, "Sirtuins, cell senescence, and vascular aging, " Canadian Journal of Cardiology, vol. 32, no. 5, pp. 634-641, 2016.
    • (2016) Canadian Journal of Cardiology , vol.32 , Issue.5 , pp. 634-641
    • Kida, Y.1    Goligorsky, M.S.2
  • 184
    • 84893403555 scopus 로고    scopus 로고
    • Dietary restriction in cerebral bioenergetics and redox state
    • I. Amigo and A. J. Kowaltowski, "Dietary restriction in cerebral bioenergetics and redox state, " Redox Biology, vol. 2, no. 1, pp. 296-304, 2014.
    • (2014) Redox Biology , vol.2 , Issue.1 , pp. 296-304
    • Amigo, I.1    Kowaltowski, A.J.2
  • 185
    • 84875656786 scopus 로고    scopus 로고
    • Hunger in the absence of caloric restriction improves cognition and attenuates Alzheimer's disease pathology in a mouse model
    • E. J. Dhurandhar, D. B. Allison, T. van Groen, and I. Kadish, "Hunger in the absence of caloric restriction improves cognition and attenuates alzheimer's disease pathology in a mouse model, " PLoS ONE, vol. 8, no. 4, Article ID e60437, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.4
    • Dhurandhar, E.J.1    Allison, D.B.2    Van Groen, T.3    Kadish, I.4
  • 186
    • 84908229188 scopus 로고    scopus 로고
    • Relationship between loneliness, psychiatric disorders and physical health A review on the psychological aspects of loneliness
    • R. Mushtaq, S. Shoib, T. Shah, and S. Mushtaq, "Relationship between loneliness, psychiatric disorders and physical health A review on the psychological aspects of loneliness, " Journal of Clinical and Diagnostic Research, vol. 8, no. 9, pp. WE01-WE04, 2014.
    • (2014) Journal of Clinical and Diagnostic Research , vol.8 , Issue.9 , pp. WE01-WE04
    • Mushtaq, R.1    Shoib, S.2    Shah, T.3    Mushtaq, S.4
  • 187
    • 84859889194 scopus 로고    scopus 로고
    • Cognitive and clinical outcomes of homocysteine-lowering Bvitamin treatment inmild cognitive impairment: A randomized controlled trial
    • C. A. de Jager, A. Oulhaj, R. Jacoby, H. Refsum, and A. D. Smith, "Cognitive and clinical outcomes of homocysteine-lowering Bvitamin treatment inmild cognitive impairment: a randomized controlled trial, " International Journal of Geriatric Psychiatry, vol. 27, no. 6, pp. 592-600, 2012.
    • (2012) International Journal of Geriatric Psychiatry , vol.27 , Issue.6 , pp. 592-600
    • De Jager, C.A.1    Oulhaj, A.2    Jacoby, R.3    Refsum, H.4    Smith, A.D.5
  • 188
    • 84965093719 scopus 로고    scopus 로고
    • Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment
    • H. Kim, G. Kim, W. Jang, S. Y. Kim, and N. Chang, "Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment, " Nutrition Journal, vol. 13, no. 1, article 118, pp. 1-11, 2014.
    • (2014) Nutrition Journal , vol.13 , Issue.1 , pp. 1-11
    • Kim, H.1    Kim, G.2    Jang, W.3    Kim, S.Y.4    Chang, N.5
  • 189
    • 36249003381 scopus 로고    scopus 로고
    • Efficacy ofmultivitamin supplementation containing vitamins b6 and b12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: A 26-week, randomized, double-blind, placebo-controlled study in Taiwanese Patients
    • Y. Sun, C.-J. Lu, K.-L. Chien, S.-T. Chen, and R.-C. Chen, "Efficacy ofmultivitamin supplementation containing vitamins b6 and b12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese Patients, " Clinical Therapeutics, vol. 29, no. 10, pp. 2204-2214, 2007.
    • (2007) Clinical Therapeutics , vol.29 , Issue.10 , pp. 2204-2214
    • Sun, Y.1    Lu, C.-J.2    Chien, K.-L.3    Chen, S.-T.4    Chen, R.-C.5
  • 190
    • 78149240857 scopus 로고    scopus 로고
    • Vitamins B12, B6, and folic acid for cognition in older men
    • A. H. Ford, L. Flicker, H. Alfonso et al., "Vitamins B12, B6, and folic acid for cognition in older men, " Neurology, vol. 75, no. 17, pp. 1540-1547, 2010.
    • (2010) Neurology , vol.75 , Issue.17 , pp. 1540-1547
    • Ford, A.H.1    Flicker, L.2    Alfonso, H.3
  • 191
    • 20344381835 scopus 로고    scopus 로고
    • Vitamin E and donepezil for the treatment of mild cognitive impairment
    • R. C. Petersen, R. G. Thomas, M. Grundman et al., "Vitamin E and donepezil for the treatment of mild cognitive impairment, " The New England Journal ofMedicine, vol. 352, no. 23, pp. 2379-2388, 2005.
    • (2005) The New England Journal OfMedicine , vol.352 , Issue.23 , pp. 2379-2388
    • Petersen, R.C.1    Thomas, R.G.2    Grundman, M.3
  • 192
    • 84871401324 scopus 로고    scopus 로고
    • Effect of one-year Vitamin C-and E-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease
    • S. Arlt, T. Müller-Thomsen, U. Beisiegel, and A. Kontush, "Effect of one-year vitamin C-and E-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease, " Neurochemical Research, vol. 37, no. 12, pp. 2706-2714, 2012.
    • (2012) Neurochemical Research , vol.37 , Issue.12 , pp. 2706-2714
    • Arlt, S.1    Müller-Thomsen, T.2    Beisiegel, U.3    Kontush, A.4
  • 196
    • 84906274315 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice
    • D. Cutuli, P. De Bartolo, P. Caporali et al., "n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice, " Frontiers in Aging Neuroscience, vol. 6, article 220, pp. 1-17, 2014.
    • (2014) Frontiers in Aging Neuroscience , vol.6 , pp. 1-17
    • Cutuli, D.1    De Bartolo, P.2    Caporali, P.3
  • 199
    • 84930816244 scopus 로고    scopus 로고
    • Flavonoid-based therapies in the early management of neurodegenerative diseases
    • I. Solanki, P. Parihar, M. L. Mansuri, and M. S. Parihar, "Flavonoid-based therapies in the early management of neurodegenerative diseases, " Advances in Nutrition, vol. 6, no. 1, pp. 64-72, 2015.
    • (2015) Advances in Nutrition , vol.6 , Issue.1 , pp. 64-72
    • Solanki, I.1    Parihar, P.2    Mansuri, M.L.3    Parihar, M.S.4
  • 201
    • 84865458738 scopus 로고    scopus 로고
    • Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: The Cocoa, Cognition, and Aging (CoCoA) study
    • G. Desideri, C. Kwik-Uribe, D. Grassi et al., "Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study, " Hypertension, vol. 60, no. 3, pp. 794-801, 2012.
    • (2012) Hypertension , vol.60 , Issue.3 , pp. 794-801
    • Desideri, G.1    Kwik-Uribe, C.2    Grassi, D.3
  • 202
    • 84920583907 scopus 로고    scopus 로고
    • Antibacterial, antioxidant, anti-cholinesterase potential and flavonol glycosides of Biscutella raphanifolia (Brassicaceae)
    • H. B. Boudouda, A. Zaghib, A. Karioti et al., "Antibacterial, antioxidant, anti-cholinesterase potential and flavonol glycosides of Biscutella raphanifolia (Brassicaceae), " Pakistan Journal of Pharmaceutical Sciences, vol. 28, no. 1, pp. 153-158, 2015.
    • (2015) Pakistan Journal of Pharmaceutical Sciences , vol.28 , Issue.1 , pp. 153-158
    • Boudouda, H.B.1    Zaghib, A.2    Karioti, A.3
  • 203
    • 79961151333 scopus 로고    scopus 로고
    • Luteolin inhibits the release of glutamate in rat cerebrocortical nerve terminals
    • T. Y. Lin, C. W. Lu, C. C. Chang, S. K. Huang, and S. J. Wang, "Luteolin inhibits the release of glutamate in rat cerebrocortical nerve terminals, " Journal of Agricultural and Food Chemistry, vol. 59, no. 15, pp. 8458-8466, 2011.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.15 , pp. 8458-8466
    • Lin, T.Y.1    Lu, C.W.2    Chang, C.C.3    Huang, S.K.4    Wang, S.J.5
  • 204
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • J. A. Baur and D. A. Sinclair, "Therapeutic potential of resveratrol: the in vivo evidence, " Nature Reviews Drug Discovery, vol. 5, no. 6, pp. 493-506, 2006.
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 205
    • 84915820956 scopus 로고    scopus 로고
    • Resveratrol as a therapeutic agent for Alzheimer's disease
    • T. Ma, M.-S. Tan, J.-T. Yu, and L. Tan, "Resveratrol as a therapeutic agent for Alzheimer's disease, " BioMed Research International, vol. 2014, Article ID 350516, 13 pages, 2014.
    • (2014) BioMed Research International , vol.2014
    • Ma, T.1    Tan, M.-S.2    Yu, J.-T.3    Tan, L.4
  • 207
    • 34547110555 scopus 로고    scopus 로고
    • Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia
    • Y. A. Kim, G.-Y. Kim, K.-Y. Park, and Y. H. Choi, "Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia, " Journal of Medicinal Food, vol. 10, no. 2, pp. 218-224, 2007.
    • (2007) Journal of Medicinal Food , vol.10 , Issue.2 , pp. 218-224
    • Kim, Y.A.1    Kim, G.-Y.2    Park, K.-Y.3    Choi, Y.H.4
  • 209
    • 28844474597 scopus 로고    scopus 로고
    • SIRT1 protects against microglia-dependent amyloid-toxicity through inhibitingNF-Bsignaling
    • J. Chen, Y. Zhou, S. Mueller-Steiner et al., "SIRT1 protects against microglia-dependent amyloid-toxicity through inhibitingNF-Bsignaling, "The Journal of Biological Chemistry, vol. 280, no. 48, pp. 40364-40374, 2005.
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 40364-40374
    • Chen, J.1    Zhou, Y.2    Mueller-Steiner, S.3
  • 211
    • 84884174276 scopus 로고    scopus 로고
    • Effects of luteolin on spatial memory, cell proliferation, and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia model
    • D. Y. Yoo, J. H. Choi, W. Kim et al., "Effects of luteolin on spatial memory, cell proliferation, and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia model, " Neurological Research, vol. 35, no. 8, pp. 813-820, 2013.
    • (2013) Neurological Research , vol.35 , Issue.8 , pp. 813-820
    • Yoo, D.Y.1    Choi, J.H.2    Kim, W.3
  • 212
    • 84874442882 scopus 로고    scopus 로고
    • Luteolin inhibits angiotensin IIinduced humanumbilical vein endothelial cell proliferation and migration through downregulation of src and Akt phosphorylation
    • M. Zhu, D. Chen, D. Li et al., "Luteolin inhibits angiotensin IIinduced humanumbilical vein endothelial cell proliferation and migration through downregulation of src and Akt phosphorylation, " Circulation Journal, vol. 77, no. 3, pp. 772-779, 2013.
    • (2013) Circulation Journal , vol.77 , Issue.3 , pp. 772-779
    • Zhu, M.1    Chen, D.2    Li, D.3
  • 213
    • 62749165351 scopus 로고    scopus 로고
    • Distribution and biological activities of the flavonoid luteolin
    • M. López-Lázaro, "Distribution and biological activities of the flavonoid luteolin, "Mini-Reviews inMedicinal Chemistry, vol. 9, no. 1, pp. 31-59, 2009.
    • (2009) Mini-Reviews InMedicinal Chemistry , vol.9 , Issue.1 , pp. 31-59
    • López-Lázaro, M.1
  • 214
    • 84925705424 scopus 로고    scopus 로고
    • Oleuropein aglycone: A possible drug against degenerative conditions. in vivo evidence of its effectiveness against Alzheimer's disease
    • F. Casamenti, C. Grossi, S. Rigacci, D. Pantano, I. Luccarini, and M. Stefani, "Oleuropein aglycone: a possible drug against degenerative conditions. In vivo evidence of its effectiveness against Alzheimer's disease, " Journal of Alzheimer's Disease, vol. 45, no. 3, pp. 679-688, 2015.
    • (2015) Journal of Alzheimer's Disease , vol.45 , Issue.3 , pp. 679-688
    • Casamenti, F.1    Grossi, C.2    Rigacci, S.3    Pantano, D.4    Luccarini, I.5    Stefani, M.6
  • 215
    • 84933515101 scopus 로고    scopus 로고
    • Cholesterol overload impairing cerebellar function: The promise of natural products
    • H. I. H. El-Sayyad, "Cholesterol overload impairing cerebellar function: the promise of natural products, " Nutrition, vol. 31, no. 5, pp. 621-630, 2015.
    • (2015) Nutrition , vol.31 , Issue.5 , pp. 621-630
    • El-Sayyad, H.I.H.1
  • 217
    • 84931572221 scopus 로고    scopus 로고
    • Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
    • M. Baumgart, H. M. Snyder, M. C. Carrillo, S. Fazio, H. Kim, and H. Johns, "Summary of the evidence on modifiable risk factors for cognitive decline and dementia: a population-based perspective, " Alzheimer's and Dementia, vol. 11, no. 6, pp. 718-726, 2015.
    • (2015) Alzheimer's and Dementia , vol.11 , Issue.6 , pp. 718-726
    • Baumgart, M.1    Snyder, H.M.2    Carrillo, M.C.3    Fazio, S.4    Kim, H.5    Johns, H.6
  • 219
    • 84876432991 scopus 로고    scopus 로고
    • Probiotics and prebiotics and health in ageing populations
    • S. H. Duncan and H. J. Flint, "Probiotics and prebiotics and health in ageing populations, " Maturitas, vol. 75, no. 1, pp. 44-50, 2013.
    • (2013) Maturitas , vol.75 , Issue.1 , pp. 44-50
    • Duncan, S.H.1    Flint, H.J.2
  • 220
    • 84908650241 scopus 로고    scopus 로고
    • Impact of the gut microbiota, prebiotics, and probiotics on human health and disease
    • C.-S. Lin, C.-J. Chang, C.-C. Lu et al., "Impact of the gut microbiota, prebiotics, and probiotics on human health and disease, " Biomedical Journal, vol. 37, no. 5, pp. 259-268, 2014.
    • (2014) Biomedical Journal , vol.37 , Issue.5 , pp. 259-268
    • Lin, C.-S.1    Chang, C.-J.2    Lu, C.-C.3
  • 221
    • 84945252690 scopus 로고    scopus 로고
    • Neuroprotective effects of Clostridium butyricum against vascular dementia in mice via metabolic butyrate
    • J. Liu, J. Sun, F. Wang et al., "Neuroprotective effects of Clostridium butyricum against vascular dementia in mice via metabolic butyrate, " BioMed Research International, vol. 2015, Article ID 412946, 12 pages, 2015.
    • (2015) BioMed Research International , vol.2015
    • Liu, J.1    Sun, J.2    Wang, F.3
  • 222
    • 84888866750 scopus 로고    scopus 로고
    • An epithelial armamentarium to sense the microbiota
    • D. Prescott, J. Lee, and D. J. Philpott, "An epithelial armamentarium to sense the microbiota, " Seminars in Immunology, vol. 25, no. 5, pp. 323-333, 2013.
    • (2013) Seminars in Immunology , vol.25 , Issue.5 , pp. 323-333
    • Prescott, D.1    Lee, J.2    Philpott, D.J.3
  • 223
    • 84955566857 scopus 로고    scopus 로고
    • Probiotic attributes, antioxidant, anti-inflammatory and neuromodulatory effects of Enterococcus faeciumCFR 3003: In vitro and in vivo evidence
    • G. Divyashri, G. Krishna, Muralidhara, and S. G. Prapulla, "Probiotic attributes, antioxidant, anti-inflammatory and neuromodulatory effects of Enterococcus faeciumCFR 3003: in vitro and in vivo evidence, " Journal of Medical Microbiology, vol. 64, no. 12, pp. 1527-1540, 2015.
    • (2015) Journal of Medical Microbiology , vol.64 , Issue.12 , pp. 1527-1540
    • Divyashri, G.1    Krishna, G.2    Muralidhara3    Prapulla, S.G.4
  • 224
    • 84947774477 scopus 로고    scopus 로고
    • Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice
    • W.-H. Liu, H.-L. Chuang, Y.-T. Huang et al., "Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice, " Behavioural Brain Research, vol. 298, pp. 202-209, 2016.
    • (2016) Behavioural Brain Research , vol.298 , pp. 202-209
    • Liu, W.-H.1    Chuang, H.-L.2    Huang, Y.-T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.