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Volumn 167, Issue , 2016, Pages 85-99

The therapeutic potential of epigenetic manipulation during infectious diseases

Author keywords

Chromatin; Epigenetic; Immune regulation

Indexed keywords

CRISPR ASSOCIATED PROTEIN; HISTONE DEACETYLASE INHIBITOR; HYBRID PROTEIN; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIINFECTIVE AGENT; HISTONE;

EID: 84981731363     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2016.07.013     Document Type: Article
Times cited : (42)

References (176)
  • 1
    • 84885099384 scopus 로고    scopus 로고
    • Alveolar macrophages in pulmonary host defence the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing
    • Aberdein, J.D., Cole, J., Bewley, M.A., Marriott, H.M., Dockrell, D.H., Alveolar macrophages in pulmonary host defence the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing. Clin Exp Immunol 174 (2013), 193–202, 10.1111/cei.12170.
    • (2013) Clin Exp Immunol , vol.174 , pp. 193-202
    • Aberdein, J.D.1    Cole, J.2    Bewley, M.A.3    Marriott, H.M.4    Dockrell, D.H.5
  • 2
    • 44749092181 scopus 로고    scopus 로고
    • Peripheral B cell subsets
    • Allman, D., Pillai, S., Peripheral B cell subsets. Curr Opin Immunol 20 (2008), 149–157, 10.1016/j.coi.2008.03.014.
    • (2008) Curr Opin Immunol , vol.20 , pp. 149-157
    • Allman, D.1    Pillai, S.2
  • 3
    • 84925546982 scopus 로고    scopus 로고
    • Epigenetic control of myeloid cell differentiation, identity and function
    • Álvarez-Errico, D., Vento-Tormo, R., Sieweke, M., Ballestar, E., Epigenetic control of myeloid cell differentiation, identity and function. Nat Rev Immunol 15:1 (2014), 7–17, 10.1038/nri3777.
    • (2014) Nat Rev Immunol , vol.15 , Issue.1 , pp. 7-17
    • Álvarez-Errico, D.1    Vento-Tormo, R.2    Sieweke, M.3    Ballestar, E.4
  • 4
    • 84867532069 scopus 로고    scopus 로고
    • Towards histone deacetylase inhibitors as new antimalarial drugs
    • Andrews, T., Tran, N., Fairlie, P., Towards histone deacetylase inhibitors as new antimalarial drugs. Curr Pharm Des 18:24 (2012), 3467–3479, 10.2174/138161212801327257.
    • (2012) Curr Pharm Des , vol.18 , Issue.24 , pp. 3467-3479
    • Andrews, T.1    Tran, N.2    Fairlie, P.3
  • 5
    • 0034924156 scopus 로고    scopus 로고
    • Epidemiology of sepsis: an update. [Review]
    • Angus, D.C.M., Wax, R.S.M., Epidemiology of sepsis: an update. [Review]. Crit Care Med, 29, 2001.
    • (2001) Crit Care Med , vol.29
    • Angus, D.C.M.1    Wax, R.S.M.2
  • 6
    • 33746806604 scopus 로고    scopus 로고
    • Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites
    • Anthony, R.M., Urban, J.F., Alem, F., Hamed, H.A., Rozo, C.T., Boucher, J.-L., et al. Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med 12 (2006), 955–960, 10.1038/nm1451.
    • (2006) Nat Med , vol.12 , pp. 955-960
    • Anthony, R.M.1    Urban, J.F.2    Alem, F.3    Hamed, H.A.4    Rozo, C.T.5    Boucher, J.-L.6
  • 7
    • 60849127627 scopus 로고    scopus 로고
    • Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid
    • Archin, N.M., Espeseth, A., Parker, D., Cheema, M., Hazuda, D., Margolis, D.M., Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. AIDS Res Hum Retrovir 25:2 (2009), 207–212.
    • (2009) AIDS Res Hum Retrovir , vol.25 , Issue.2 , pp. 207-212
    • Archin, N.M.1    Espeseth, A.2    Parker, D.3    Cheema, M.4    Hazuda, D.5    Margolis, D.M.6
  • 8
    • 70249100307 scopus 로고    scopus 로고
    • Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors
    • Archin, N.M., Keedy, K.S., Espeseth, A., Dang, H., Hazuda, D.J., Margolis, D.M., Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors. AIDS (London, England) 23:14 (2009), 1799–1806.
    • (2009) AIDS (London, England) , vol.23 , Issue.14 , pp. 1799-1806
    • Archin, N.M.1    Keedy, K.S.2    Espeseth, A.3    Dang, H.4    Hazuda, D.J.5    Margolis, D.M.6
  • 9
    • 84906764768 scopus 로고    scopus 로고
    • HIV-1 expression within resting CD4 + T cells after multiple doses of vorinostat
    • Archin, N.M., Bateson, R., Tripathy, M.K., Crooks, A.M., Yang, K., Dahl, N.P., et al. HIV-1 expression within resting CD4 + T cells after multiple doses of vorinostat. J Infect Dis 210:5 (2014), 728–735.
    • (2014) J Infect Dis , vol.210 , Issue.5 , pp. 728-735
    • Archin, N.M.1    Bateson, R.2    Tripathy, M.K.3    Crooks, A.M.4    Yang, K.5    Dahl, N.P.6
  • 10
    • 50949131800 scopus 로고    scopus 로고
    • Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4 + T cells
    • Archin, N.M., Eron, J., Palmer, S., Hartmann-Duff, A., Martinson, J.A., Wiegand, A., et al. Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4 + T cells. AIDS (London, England) 22:10 (2008), 1131–1135.
    • (2008) AIDS (London, England) , vol.22 , Issue.10 , pp. 1131-1135
    • Archin, N.M.1    Eron, J.2    Palmer, S.3    Hartmann-Duff, A.4    Martinson, J.A.5    Wiegand, A.6
  • 11
    • 84864203255 scopus 로고    scopus 로고
    • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
    • Archin, N.M., Liberty, A.L., Kashuba, A.D., Choudhary, S.K., Kuruc, J.D., Crooks, A.M., et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487:7408 (2012), 482–485.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 482-485
    • Archin, N.M.1    Liberty, A.L.2    Kashuba, A.D.3    Choudhary, S.K.4    Kuruc, J.D.5    Crooks, A.M.6
  • 13
    • 84960145110 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors promote mitochondrial reactive oxygen species production and bacterial clearance by human macrophages
    • 01876-15
    • Ariffin, J.K., Gupta, K.d., Kapetanovic, R., Iyer, A., Reid, R.C., Fairlie, D.P., Sweet, M.J., Histone deacetylase inhibitors promote mitochondrial reactive oxygen species production and bacterial clearance by human macrophages. Antimicrob Agents Chemother, 2015, 10.1128/AAC.01876-15 01876-15.
    • (2015) Antimicrob Agents Chemother
    • Ariffin, J.K.1    Gupta, K.D.2    Kapetanovic, R.3    Iyer, A.4    Reid, R.C.5    Fairlie, D.P.6    Sweet, M.J.7
  • 15
    • 84878489387 scopus 로고    scopus 로고
    • HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages
    • e1003503
    • Barneda-Zahonero, B., Román-González, L., Collazo, O., Rafati, H., Islam, A.B.M.M.K., Bussmann, L.H.,.. Parra, M., HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages. PLoS Genet, 9(5), 2013, e1003503, 10.1371/journal.pgen.1003503.
    • (2013) PLoS Genet , vol.9 , Issue.5
    • Barneda-Zahonero, B.1    Román-González, L.2    Collazo, O.3    Rafati, H.4    Islam, A.B.M.M.K.5    Bussmann, L.H.6    Parra, M.7
  • 16
    • 67650650890 scopus 로고    scopus 로고
    • Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
    • Bending, D., De la Peña, H., Veldhoen, M., Phillips, J.M., Uyttenhove, C., Stockinger, B., et al. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest 119 (2009), 565–572, 10.1172/JCI37865.
    • (2009) J Clin Invest , vol.119 , pp. 565-572
    • Bending, D.1    De la Peña, H.2    Veldhoen, M.3    Phillips, J.M.4    Uyttenhove, C.5    Stockinger, B.6
  • 19
    • 84864934043 scopus 로고    scopus 로고
    • Effect of histone deacetylase inhibitors on HIV production in latently infected, resting CD4(+) T cells from infected individuals receiving effective antiretroviral therapy
    • Blazkova, J., Chun, T.-W., Belay, B.W., Murray, D., Justement, J.S., Funk, E.K., et al. Effect of histone deacetylase inhibitors on HIV production in latently infected, resting CD4(+) T cells from infected individuals receiving effective antiretroviral therapy. J Infect Dis 206:5 (2012), 765–769.
    • (2012) J Infect Dis , vol.206 , Issue.5 , pp. 765-769
    • Blazkova, J.1    Chun, T.-W.2    Belay, B.W.3    Murray, D.4    Justement, J.S.5    Funk, E.K.6
  • 20
    • 84861314042 scopus 로고    scopus 로고
    • Paucity of HIV DNA methylation in latently infected, resting CD4 + T cells from infected individuals receiving antiretroviral therapy
    • Blazkova, J., Murray, D., Justement, J., Funk, E., Nelson, A.K., Moir, S., et al. Paucity of HIV DNA methylation in latently infected, resting CD4 + T cells from infected individuals receiving antiretroviral therapy. J Virol 86:9 (2012), 5390–5392.
    • (2012) J Virol , vol.86 , Issue.9 , pp. 5390-5392
    • Blazkova, J.1    Murray, D.2    Justement, J.3    Funk, E.4    Nelson, A.K.5    Moir, S.6
  • 21
    • 70049090006 scopus 로고    scopus 로고
    • CpG methylation controls reactivation of HIV from latency T. J. Hope, ed
    • pp. e1000554–14
    • Blazkova, J., Trejbalova, K., Gondois-Rey, F., Halfon, P., Philibert, P., Guiguen, A., et al. CpG methylation controls reactivation of HIV from latency T. J. Hope, ed. PLoS Pathog, 5(8), 2009 pp. e1000554–14.
    • (2009) PLoS Pathog , vol.5 , Issue.8
    • Blazkova, J.1    Trejbalova, K.2    Gondois-Rey, F.3    Halfon, P.4    Philibert, P.5    Guiguen, A.6
  • 22
    • 79955970344 scopus 로고    scopus 로고
    • Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood 117: e182–e189
    • Bocker, M.T., Hellwig, M., Breiling, A., Eckstein, V., Ho, A.D., Lyko, F., Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood 117: e182–e189. Blood 117:19 (2011), e182–e189, 10.1182/blood-2011-01-331926.
    • (2011) Blood , vol.117 , Issue.19 , pp. e182-e189
    • Bocker, M.T.1    Hellwig, M.2    Breiling, A.3    Eckstein, V.4    Ho, A.D.5    Lyko, F.6
  • 23
    • 84921060280 scopus 로고    scopus 로고
    • BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak–STAT signaling in a gene-specific manner in human monocytes
    • Chan, C.H., Fang, C., Qiao, Y., Yarilina, A., Prinjha, R.K., Ivashkiv, L.B., BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak–STAT signaling in a gene-specific manner in human monocytes. Eur J Immunol 45 (2015), 287–297, 10.1002/eji.201444862.
    • (2015) Eur J Immunol , vol.45 , pp. 287-297
    • Chan, C.H.1    Fang, C.2    Qiao, Y.3    Yarilina, A.4    Prinjha, R.K.5    Ivashkiv, L.B.6
  • 24
    • 35348938519 scopus 로고    scopus 로고
    • JMJD6 is a histone arginine demethylase
    • Chang, B., Chen, Y., Zhao, Y., Bruick, R.K., JMJD6 is a histone arginine demethylase. Science 318 (2007), 444–447, 10.1126/science.1145801.
    • (2007) Science , vol.318 , pp. 444-447
    • Chang, B.1    Chen, Y.2    Zhao, Y.3    Bruick, R.K.4
  • 25
    • 84911201387 scopus 로고    scopus 로고
    • Molecular regulation of effector and memory T cell differentiation
    • Chang, J.T., Wherry, E.J., Goldrath, A.W., Molecular regulation of effector and memory T cell differentiation. Nat Immunol 15:12 (2014), 1104–1115, 10.1038/ni.3031.
    • (2014) Nat Immunol , vol.15 , Issue.12 , pp. 1104-1115
    • Chang, J.T.1    Wherry, E.J.2    Goldrath, A.W.3
  • 26
    • 79961215084 scopus 로고    scopus 로고
    • Life and death of transcriptional co-activator p300
    • Chen, J., Li, Q., Life and death of transcriptional co-activator p300. Epigenetics 6 (2011), 957–961, 10.4161/epi.6.8.16065.
    • (2011) Epigenetics , vol.6 , pp. 957-961
    • Chen, J.1    Li, Q.2
  • 27
    • 84867652835 scopus 로고    scopus 로고
    • Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
    • Chen, X., Barozzi, I., Termanini, A., Prosperini, E., Recchiuti, A., Dalli, J.,.. Natoli, G., Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc Natl Acad Sci 109:42 (2012), E2865–E2874, 10.1073/pnas.1121131109.
    • (2012) Proc Natl Acad Sci , vol.109 , Issue.42 , pp. E2865-E2874
    • Chen, X.1    Barozzi, I.2    Termanini, A.3    Prosperini, E.4    Recchiuti, A.5    Dalli, J.6    Natoli, G.7
  • 28
    • 66149086936 scopus 로고    scopus 로고
    • NOD-like receptors: role in innate immunity and inflammatory disease
    • Chen, G., Shaw, M.H., Kim, Y.-G., Nuñez, G., NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol 4 (2009), 365–398, 10.1146/annurev.pathol.4.110807.092239.
    • (2009) Annu Rev Pathol , vol.4 , pp. 365-398
    • Chen, G.1    Shaw, M.H.2    Kim, Y.-G.3    Nuñez, G.4
  • 29
    • 84930178001 scopus 로고    scopus 로고
    • Selective histone deacetylase 6 inhibition prolongs survival in a lethal two-hit model
    • Cheng, X., Liu, Z., Liu, B., Zhao, T., Li, Y., Alam, H.B., Selective histone deacetylase 6 inhibition prolongs survival in a lethal two-hit model. J Surg Res 197 (2015), 39–44, 10.1016/j.jss.2015.02.070.
    • (2015) J Surg Res , vol.197 , pp. 39-44
    • Cheng, X.1    Liu, Z.2    Liu, B.3    Zhao, T.4    Li, Y.5    Alam, H.B.6
  • 30
    • 84909578049 scopus 로고    scopus 로고
    • mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
    • Cheng, S.C., Quintin, J., Cramer, R.A., Shepardson, K.M., Saeed, S., Kumar, V., et al. mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity. Science, 345, 2014, 1250684, 10.1126/science.1250684.
    • (2014) Science , vol.345 , pp. 1250684
    • Cheng, S.C.1    Quintin, J.2    Cramer, R.A.3    Shepardson, K.M.4    Saeed, S.5    Kumar, V.6
  • 31
    • 27644524761 scopus 로고    scopus 로고
    • HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir
    • Chun, T.-W., Nickle, D.C., Justement, J.S., Large, D., Semerjian, A., Curlin, M.E., et al. HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir. J Clin Invest 115:11 (2005), 3250–3255.
    • (2005) J Clin Invest , vol.115 , Issue.11 , pp. 3250-3255
    • Chun, T.-W.1    Nickle, D.C.2    Justement, J.S.3    Large, D.4    Semerjian, A.5    Curlin, M.E.6
  • 32
    • 0017229979 scopus 로고
    • Protection of mice against Babesia, and Plasmodium with BCG
    • Clark, I.A., Allison, A.C., Cox, F.E., Protection of mice against Babesia, and Plasmodium with BCG. Nature 259 (1976), 309–311, 10.1038/259309a0.
    • (1976) Nature , vol.259 , pp. 309-311
    • Clark, I.A.1    Allison, A.C.2    Cox, F.E.3
  • 33
    • 84936889694 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes
    • Collins, P.L., Kyle, K.E., Egawa, T., Shinkai, Y., Oltz, E.M., The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes. Proc Natl Acad Sci U S A 112:27 (2015), 8367–8372, 10.1073/pnas.1422187112.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.27 , pp. 8367-8372
    • Collins, P.L.1    Kyle, K.E.2    Egawa, T.3    Shinkai, Y.4    Oltz, E.M.5
  • 35
    • 77953540361 scopus 로고    scopus 로고
    • Epigenomics of T cell activation, differentiation and memory
    • Cuddapah, S., Barski, A., Zhao, K., Epigenomics of T cell activation, differentiation and memory. Curr Opin Immunol 22 (2010), 341–347, 10.1016/j.coi.2010.02.007.
    • (2010) Curr Opin Immunol , vol.22 , pp. 341-347
    • Cuddapah, S.1    Barski, A.2    Zhao, K.3
  • 36
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages
    • e8668
    • Daigneault, M., Preston, J.A., Marriott, H.M., Whyte, M.K.B., Dockrell, D.H., The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS One, 5, 2010, e8668, 10.1371/journal.pone.0008668.
    • (2010) PLoS One , vol.5
    • Daigneault, M.1    Preston, J.A.2    Marriott, H.M.3    Whyte, M.K.B.4    Dockrell, D.H.5
  • 37
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-γ genes
    • Dalton, D.K., Pitts-Meek, S., Keshav, S., Figari, I.S., Bradley, A., Stewart, T.A., Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259 (1993), 1739–1742.
    • (1993) Science , vol.259 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 38
    • 80054984945 scopus 로고    scopus 로고
    • Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
    • Dawson, M.A., Prinjha, R.K., Dittman, A., Giotopoulos, G., Bantscheff, M., Chan, W.-I., et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 478 (2011), 529–533, 10.1038/nature10509.
    • (2011) Nature , vol.478 , pp. 529-533
    • Dawson, M.A.1    Prinjha, R.K.2    Dittman, A.3    Giotopoulos, G.4    Bantscheff, M.5    Chan, W.-I.6
  • 39
    • 70350754328 scopus 로고    scopus 로고
    • Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
    • De Santa, F., Narang, V., Yap, Z.H., Tusi, B.K., Burgold, T., Austenaa, L., et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO J 28 (2009), 3341–3352, 10.1038/emboj.2009.271.
    • (2009) EMBO J , vol.28 , pp. 3341-3352
    • De Santa, F.1    Narang, V.2    Yap, Z.H.3    Tusi, B.K.4    Burgold, T.5    Austenaa, L.6
  • 40
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis, R.J., Lum, J.J., Hatzivassiliou, G., Thompson, C.B., The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7 (2008), 11–20, 10.1016/j.cmet.2007.10.002.
    • (2008) Cell Metab , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 41
    • 84864243685 scopus 로고    scopus 로고
    • HIV: shock and kill
    • Deeks, S.G., HIV: shock and kill. Nature 487:7408 (2012), 439–440.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 439-440
    • Deeks, S.G.1
  • 43
    • 80052955256 scopus 로고    scopus 로고
    • BET bromodomain inhibition as a therapeutic strategy to target c-Myc
    • Delmore, J.E., Issa, G.C., Lemieux, M.E., Rahl, P.B., Shi, J., Jacobs, H.M., et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146 (2011), 904–917, 10.1016/j.cell.2011.08.017.
    • (2011) Cell , vol.146 , pp. 904-917
    • Delmore, J.E.1    Issa, G.C.2    Lemieux, M.E.3    Rahl, P.B.4    Shi, J.5    Jacobs, H.M.6
  • 44
    • 23944509075 scopus 로고    scopus 로고
    • The SET-domain protein superfamily: protein lysine methyltransferases
    • Dillon, S.C., Zhang, X., Trievel, R.C., Cheng, X., The SET-domain protein superfamily: protein lysine methyltransferases. Genome Biol, 6(8), 2005, 227, 10.1186/gb-2005-6-8-227.
    • (2005) Genome Biol , vol.6 , Issue.8 , pp. 227
    • Dillon, S.C.1    Zhang, X.2    Trievel, R.C.3    Cheng, X.4
  • 45
    • 77956303574 scopus 로고    scopus 로고
    • Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis
    • e9875
    • Ding, S.-Z., Fischer, W., Kaparakis-Liaskos, M., Liechti, G., Merrell, D.S., Grant, P.A., et al. Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis. PLoS One, 5, 2010, e9875, 10.1371/journal.pone.0009875.
    • (2010) PLoS One , vol.5
    • Ding, S.-Z.1    Fischer, W.2    Kaparakis-Liaskos, M.3    Liechti, G.4    Merrell, D.S.5    Grant, P.A.6
  • 46
    • 77954462446 scopus 로고    scopus 로고
    • Histone acetylation at the single-cell level: a marker of memory CD8 + T cell differentiation and functionality
    • DiSpirito, J.R., Shen, H., Histone acetylation at the single-cell level: a marker of memory CD8 + T cell differentiation and functionality. J Immunol 184 (2010), 4631–4636, 10.4049/jimmunol.0903830.
    • (2010) J Immunol , vol.184 , pp. 4631-4636
    • DiSpirito, J.R.1    Shen, H.2
  • 47
    • 84864795837 scopus 로고    scopus 로고
    • Pneumococcal pneumonia: mechanisms of infection and resolution
    • Dockrell, D.H., Whyte, M.K.B., Mitchell, T.J., Pneumococcal pneumonia: mechanisms of infection and resolution. Chest 142 (2012), 482–491, 10.1378/chest.12-0210.
    • (2012) Chest , vol.142 , pp. 482-491
    • Dockrell, D.H.1    Whyte, M.K.B.2    Mitchell, T.J.3
  • 48
    • 4744349055 scopus 로고    scopus 로고
    • Systemic acquired resistance
    • Durrant, W.E., Dong, X., Systemic acquired resistance. Annu Rev Phytopathol 42 (2004), 185–209, 10.1146/annurev.phyto.42.040803.140421.
    • (2004) Annu Rev Phytopathol , vol.42 , pp. 185-209
    • Durrant, W.E.1    Dong, X.2
  • 49
    • 0035887504 scopus 로고    scopus 로고
    • Reprogramming of the macrophage transcriptome in response to interferon-γ and mycobacterium tuberculosis signaling roles of nitric oxide synthase-2 and phagocyte oxidase
    • Ehrt, S., Schnappinger, D., Bekiranov, S., Drenkow, J., Shi, S., Gingeras, T.R., et al. Reprogramming of the macrophage transcriptome in response to interferon-γ and mycobacterium tuberculosis signaling roles of nitric oxide synthase-2 and phagocyte oxidase. J Exp Med 194 (2001), 1123–1140, 10.1084/jem.194.8.1123.
    • (2001) J Exp Med , vol.194 , pp. 1123-1140
    • Ehrt, S.1    Schnappinger, D.2    Bekiranov, S.3    Drenkow, J.4    Shi, S.5    Gingeras, T.R.6
  • 50
    • 84881034102 scopus 로고    scopus 로고
    • A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection
    • Eskandarian, H.A., Impens, F., Nahori, M.-A., Soubigou, G., Coppée, J.-Y., Cossart, et al. A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection. Science, 341, 2013, 1238858, 10.1126/science.1238858.
    • (2013) Science , vol.341 , pp. 1238858
    • Eskandarian, H.A.1    Impens, F.2    Nahori, M.-A.3    Soubigou, G.4    Coppée, J.-Y.5    Cossart6
  • 51
    • 84946595415 scopus 로고    scopus 로고
    • Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers
    • e01187–15
    • Esterhuyse, M.M., Weiner, J., Caron, E., Loxton, A.G., Iannaccone, M., Wagman, C.,.. Kaufmann, S.H.E., Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers. mBio, 6(5), 2015, 10.1128/mBio.01187-15 e01187–15.
    • (2015) mBio , vol.6 , Issue.5
    • Esterhuyse, M.M.1    Weiner, J.2    Caron, E.3    Loxton, A.G.4    Iannaccone, M.5    Wagman, C.6    Kaufmann, S.H.E.7
  • 52
    • 84908265816 scopus 로고    scopus 로고
    • Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
    • Falkenberg, K.J., Johnstone, R.W., Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov 13:9 (2014), 673–691, 10.1038/nrd4360.
    • (2014) Nat Rev Drug Discov , vol.13 , Issue.9 , pp. 673-691
    • Falkenberg, K.J.1    Johnstone, R.W.2
  • 53
    • 74549131857 scopus 로고    scopus 로고
    • Helicobacter pylori-induced modification of the histone H3 phosphorylation status in gastric epithelial cells reflects its impact on cell cycle regulation
    • Fehri, L.F., Rechner, C., Janßen, S., Mak, T.N., Holland, C., Bartfeld, S., et al. Helicobacter pylori-induced modification of the histone H3 phosphorylation status in gastric epithelial cells reflects its impact on cell cycle regulation. Epigenetics 4 (2009), 577–586, 10.4161/epi.4.8.10217.
    • (2009) Epigenetics , vol.4 , pp. 577-586
    • Fehri, L.F.1    Rechner, C.2    Janßen, S.3    Mak, T.N.4    Holland, C.5    Bartfeld, S.6
  • 54
    • 84939832172 scopus 로고    scopus 로고
    • Dimethylated H3K27 is a repressive epigenetic histone mark in the Protist Entamoeba histolytica and is significantly enriched in genes silenced via the RNAi pathway
    • Foda, B.M., Singh, U., Dimethylated H3K27 is a repressive epigenetic histone mark in the Protist Entamoeba histolytica and is significantly enriched in genes silenced via the RNAi pathway. J Biol Chem 290:34 (2015), 21114–21130, 10.1074/jbc.M115.647263.
    • (2015) J Biol Chem , vol.290 , Issue.34 , pp. 21114-21130
    • Foda, B.M.1    Singh, U.2
  • 55
    • 57149107350 scopus 로고    scopus 로고
    • Gene-specific control of the TLR-induced inflammatory response
    • Foster, S.L., Medzhitov, R., Gene-specific control of the TLR-induced inflammatory response. Clin Immunol 130 (2009), 7–15, 10.1016/j.clim.2008.08.015.
    • (2009) Clin Immunol , vol.130 , pp. 7-15
    • Foster, S.L.1    Medzhitov, R.2
  • 56
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster, S.L., Hargreaves, D.C., Medzhitov, R., Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447 (2007), 972–978, 10.1038/nature05836.
    • (2007) Nature , vol.447 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 57
    • 80052287096 scopus 로고    scopus 로고
    • Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2
    • Friedman, J., Cho, W.-K., Chu, C.K., Keedy, K.S., Archin, N.M., Margolis, D.M., et al. Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2. J Virol 85:17 (2011), 9078–9089.
    • (2011) J Virol , vol.85 , Issue.17 , pp. 9078-9089
    • Friedman, J.1    Cho, W.-K.2    Chu, C.K.3    Keedy, K.S.4    Archin, N.M.5    Margolis, D.M.6
  • 58
    • 84895797883 scopus 로고    scopus 로고
    • Subsets of human natural killer cells and their regulatory effects
    • Fu, B., Tian, Z., Wei, H., Subsets of human natural killer cells and their regulatory effects. Immunology 141 (2014), 483–489, 10.1111/imm.12224.
    • (2014) Immunology , vol.141 , pp. 483-489
    • Fu, B.1    Tian, Z.2    Wei, H.3
  • 59
    • 67650886021 scopus 로고    scopus 로고
    • Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum
    • e1000488
    • Garcia-Garcia, J.C., Barat, N.C., Trembley, S.J., Dumler, J.S., Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. PLoS Pathog, 5(6), 2009, e1000488, 10.1371/journal.ppat.1000488.
    • (2009) PLoS Pathog , vol.5 , Issue.6
    • Garcia-Garcia, J.C.1    Barat, N.C.2    Trembley, S.J.3    Dumler, J.S.4
  • 60
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • Ghisletti, S., Barozzi, I., Mietton, F., Polletti, S., De Santa, F., Venturini, E., et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32 (2010), 317–328, 10.1016/j.immuni.2010.02.008.
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1    Barozzi, I.2    Mietton, F.3    Polletti, S.4    De Santa, F.5    Venturini, E.6
  • 61
    • 84906086839 scopus 로고    scopus 로고
    • HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages
    • Ha, S.-D., Han, C.Y., Reid, C., Kim, S.O., HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages. J Immunol 193:3 (2014), 1333–1343, 10.4049/jimmunol.1400420.
    • (2014) J Immunol , vol.193 , Issue.3 , pp. 1333-1343
    • Ha, S.-D.1    Han, C.Y.2    Reid, C.3    Kim, S.O.4
  • 62
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: biological insights and disease relevance
    • Haigis, M.C., Sinclair, D.A., Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 5 (2010), 253–295, 10.1146/annurev.pathol.4.110807.092250.
    • (2010) Annu Rev Pathol , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 64
    • 84859958476 scopus 로고    scopus 로고
    • Epigenetic regulation of tumor necrosis factor α (TNFα) release in human macrophages by HIV-1 single-stranded RNA (ssRNA) is dependent on TLR8 signaling
    • Han, X., Li, X., Yue, S.C., Anandaiah, A., Hashem, F., Reinach, P.S.,.. Tachado, S.D., Epigenetic regulation of tumor necrosis factor α (TNFα) release in human macrophages by HIV-1 single-stranded RNA (ssRNA) is dependent on TLR8 signaling. J Biol Chem 287:17 (2012), 13778–13786, 10.1074/jbc.M112.342683.
    • (2012) J Biol Chem , vol.287 , Issue.17 , pp. 13778-13786
    • Han, X.1    Li, X.2    Yue, S.C.3    Anandaiah, A.4    Hashem, F.5    Reinach, P.S.6    Tachado, S.D.7
  • 65
    • 84911453780 scopus 로고    scopus 로고
    • Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF
    • Harouz, H., Rachez, C., Meijer, B.M., Marteyn, B., Donnadieu, F., Cammas, F.,.. Arbibe, L., Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF. EMBO J 33:22 (2014), 2606–2622, 10.15252/embj.201489244.
    • (2014) EMBO J , vol.33 , Issue.22 , pp. 2606-2622
    • Harouz, H.1    Rachez, C.2    Meijer, B.M.3    Marteyn, B.4    Donnadieu, F.5    Cammas, F.6    Arbibe, L.7
  • 66
    • 84914689416 scopus 로고    scopus 로고
    • A novel role of SIRT1 in gammaherpesvirus latency and replication
    • He, M., Gao, S.-J., A novel role of SIRT1 in gammaherpesvirus latency and replication. Cell Cycle 13:21 (2014), 3328–3330, 10.4161/15384101.2014.968431.
    • (2014) Cell Cycle , vol.13 , Issue.21 , pp. 3328-3330
    • He, M.1    Gao, S.-J.2
  • 68
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • Heintzman, N.D., Hon, G.C., Hawkins, R.D., Kheradpour, P., Stark, A., Harp, L.F., et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459 (2009), 108–112, 10.1038/nature07829.
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5    Harp, L.F.6
  • 69
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining TFs prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y.C., Laslo, P.,.. Glass, C.K., Simple combinations of lineage-determining TFs prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 38:4 (2010), 576–589, 10.1016/j.molcel.2010.05.004.
    • (2010) Mol Cell , vol.38 , Issue.4 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6    Glass, C.K.7
  • 70
    • 84929135130 scopus 로고    scopus 로고
    • Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
    • Hilton, I.B., D'Ippolito, A.M., Vockley, C.M., Thakore, P.I., Crawford, G.E., Reddy, T.E., et al. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat Biotechnol 33 (2015), 510–517, 10.1038/nbt.3199.
    • (2015) Nat Biotechnol , vol.33 , pp. 510-517
    • Hilton, I.B.1    D'Ippolito, A.M.2    Vockley, C.M.3    Thakore, P.I.4    Crawford, G.E.5    Reddy, T.E.6
  • 71
    • 50149094330 scopus 로고    scopus 로고
    • Adenovirus small e1a alters global patterns of histone modification
    • Horwitz, G.A., Zhang, K., McBrian, M.A., Grunstein, M., Kurdistani, S.K., Berk, A.J., Adenovirus small e1a alters global patterns of histone modification. Science 321:5892 (2008), 1084–1085, 10.1126/science.1155544.
    • (2008) Science , vol.321 , Issue.5892 , pp. 1084-1085
    • Horwitz, G.A.1    Zhang, K.2    McBrian, M.A.3    Grunstein, M.4    Kurdistani, S.K.5    Berk, A.J.6
  • 72
    • 84895800375 scopus 로고    scopus 로고
    • Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors
    • 00688-13
    • Ifrim, D.C., Quintin, J., Joosten, L.A.B., Jacobs, C., Jansen, T., Jacobs, L., et al. Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors. Clin Vaccine Immunol, 2014, 10.1128/CVI.00688-13 00688-13.
    • (2014) Clin Vaccine Immunol
    • Ifrim, D.C.1    Quintin, J.2    Joosten, L.A.B.3    Jacobs, C.4    Jansen, T.5    Jacobs, L.6
  • 73
    • 77952767617 scopus 로고    scopus 로고
    • Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294
    • Imai, K., Togami, H., Okamoto, T., Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294. J Biol Chem 285:22 (2010), 16538–16545.
    • (2010) J Biol Chem , vol.285 , Issue.22 , pp. 16538-16545
    • Imai, K.1    Togami, H.2    Okamoto, T.3
  • 74
    • 70350435962 scopus 로고    scopus 로고
    • Epigenetic regulation of the alternatively activated macrophage phenotype
    • Ishii, M., Wen, H., Corsa, C.A.S., Liu, T., Coelho, A.L., Allen, R.M.,.. Kunkel, S.L., Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 114:15 (2009), 3244–3254, 10.1182/blood-2009-04-217620.
    • (2009) Blood , vol.114 , Issue.15 , pp. 3244-3254
    • Ishii, M.1    Wen, H.2    Corsa, C.A.S.3    Liu, T.4    Coelho, A.L.5    Allen, R.M.6    Kunkel, S.L.7
  • 75
    • 84877119701 scopus 로고    scopus 로고
    • Epigenetic regulation of macrophage polarization and function
    • Ivashkiv, L.B., Epigenetic regulation of macrophage polarization and function. Trends Immunol 34:5 (2013), 216–223, 10.1016/j.it.2012.11.001.
    • (2013) Trends Immunol , vol.34 , Issue.5 , pp. 216-223
    • Ivashkiv, L.B.1
  • 76
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein, T., Allis, C.D., Translating the histone code. Science 293 (2001), 1074–1080, 10.1126/science.1063127.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 77
    • 40949162838 scopus 로고    scopus 로고
    • The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease
    • Kadioglu, A., Weiser, J.N., Paton, J.C., Andrew, P.W., The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol 6 (2008), 288–301, 10.1038/nrmicro1871.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 288-301
    • Kadioglu, A.1    Weiser, J.N.2    Paton, J.C.3    Andrew, P.W.4
  • 78
    • 84881526410 scopus 로고    scopus 로고
    • Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
    • Kaikkonen, M.U., Spann, N., Heinz, S., Romanoski, C.E., Allison, K.A., Stender, J.D.,.. Glass, C.K., Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell 51:3 (2013), 310–325, 10.1016/j.molcel.2013.07.010.
    • (2013) Mol Cell , vol.51 , Issue.3 , pp. 310-325
    • Kaikkonen, M.U.1    Spann, N.2    Heinz, S.3    Romanoski, C.E.4    Allison, K.A.5    Stender, J.D.6    Glass, C.K.7
  • 79
    • 84859401055 scopus 로고    scopus 로고
    • Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity
    • Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K., O'Shea, J.J., Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu Rev Immunol 30 (2012), 707–731, 10.1146/annurev-immunol-020711-075058.
    • (2012) Annu Rev Immunol , vol.30 , pp. 707-731
    • Kanno, Y.1    Vahedi, G.2    Hirahara, K.3    Singleton, K.4    O'Shea, J.J.5
  • 80
    • 67650925025 scopus 로고    scopus 로고
    • Epigenetic regulation of HIV-1 latency by cytosine methylation S. Ross, ed
    • pp. e1000495–15
    • Kauder, S.E., Bosque, A., Lindqvist, A., Planelles, V., Verdin, E., Epigenetic regulation of HIV-1 latency by cytosine methylation S. Ross, ed. PLoS Pathog, 5(6), 2009 pp. e1000495–15.
    • (2009) PLoS Pathog , vol.5 , Issue.6
    • Kauder, S.E.1    Bosque, A.2    Lindqvist, A.3    Planelles, V.4    Verdin, E.5
  • 81
    • 84928924333 scopus 로고    scopus 로고
    • Functional annotation of native enhancers with a Cas9-histone demethylase fusion
    • Kearns, N.A., Pham, H., Tabak, B., Genga, R.M., Silverstein, N.J., Garber, M., Maehr, R., Functional annotation of native enhancers with a Cas9-histone demethylase fusion. Nat Methods 12:5 (2015), 401–403, 10.1038/nmeth.3325.
    • (2015) Nat Methods , vol.12 , Issue.5 , pp. 401-403
    • Kearns, N.A.1    Pham, H.2    Tabak, B.3    Genga, R.M.4    Silverstein, N.J.5    Garber, M.6    Maehr, R.7
  • 82
    • 65349193781 scopus 로고    scopus 로고
    • A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression
    • Keedy, K.S., Archin, N.M., Gates, A.T., Espeseth, A., Hazuda, D.J., Margolis, D.M., A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. J Virol 83:10 (2009), 4749–4756.
    • (2009) J Virol , vol.83 , Issue.10 , pp. 4749-4756
    • Keedy, K.S.1    Archin, N.M.2    Gates, A.T.3    Espeseth, A.4    Hazuda, D.J.5    Margolis, D.M.6
  • 83
    • 84867909516 scopus 로고    scopus 로고
    • Bacille Calmette–Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
    • Kleinnijenhuis, J., Quintin, J., Preijers, F., Joosten, L.A.B., Ifrim, D.C., Saeed, S., et al. Bacille Calmette–Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes. Proc Natl Acad Sci U S A 109 (2012), 17537–17542, 10.1073/pnas.1202870109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 17537-17542
    • Kleinnijenhuis, J.1    Quintin, J.2    Preijers, F.3    Joosten, L.A.B.4    Ifrim, D.C.5    Saeed, S.6
  • 84
    • 84910058768 scopus 로고    scopus 로고
    • BCG-induced trained immunity in NK cells: role for non-specific protection to infection
    • Kleinnijenhuis, J., Quintin, J., Preijers, F., Joosten, L.A.B., Jacobs, C., Xavier, R.J., et al. BCG-induced trained immunity in NK cells: role for non-specific protection to infection. Clin Immunol 155 (2014), 213–219, 10.1016/j.clim.2014.10.005.
    • (2014) Clin Immunol , vol.155 , pp. 213-219
    • Kleinnijenhuis, J.1    Quintin, J.2    Preijers, F.3    Joosten, L.A.B.4    Jacobs, C.5    Xavier, R.J.6
  • 85
    • 0036532202 scopus 로고    scopus 로고
    • Histone methylation in transcriptional control
    • Kouzarides, T., Histone methylation in transcriptional control. Curr Opin Genet Dev 12:2 (2002), 198–209.
    • (2002) Curr Opin Genet Dev , vol.12 , Issue.2 , pp. 198-209
    • Kouzarides, T.1
  • 86
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides, T., Chromatin modifications and their function. Cell 128:4 (2007), 693–705, 10.1016/j.cell.2007.02.005.
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 87
    • 84865120905 scopus 로고    scopus 로고
    • A selective Jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
    • Kruidenier, L., Chung, C., Cheng, Z., Liddle, J., Che, K., Joberty, G., et al. A selective Jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488 (2012), 404–408, 10.1038/nature11262.
    • (2012) Nature , vol.488 , pp. 404-408
    • Kruidenier, L.1    Chung, C.2    Cheng, Z.3    Liddle, J.4    Che, K.5    Joberty, G.6
  • 88
    • 84913607311 scopus 로고    scopus 로고
    • Epigenetic regulation of human cytomegalovirus latency: an update
    • Kumar, A., Herbein, G., Epigenetic regulation of human cytomegalovirus latency: an update. Epigenomics 6:5 (2014), 533–546, 10.2217/epi.14.41.
    • (2014) Epigenomics , vol.6 , Issue.5 , pp. 533-546
    • Kumar, A.1    Herbein, G.2
  • 89
    • 84948744157 scopus 로고    scopus 로고
    • Epigenetics: the genome unwrapped
    • Ledford, H., Epigenetics: the genome unwrapped. Nature 528:7580 (2015), S12–S13, 10.1038/528S12a.
    • (2015) Nature , vol.528 , Issue.7580 , pp. S12-S13
    • Ledford, H.1
  • 90
    • 0038341918 scopus 로고    scopus 로고
    • Histone acetylation and chromatin conformation are regulated separately at the TNF-α promoter in monocytes and macrophages
    • Lee, J.Y., Kim, N.A., Sanford, A., Sullivan, K.E., Histone acetylation and chromatin conformation are regulated separately at the TNF-α promoter in monocytes and macrophages. J Leukoc Biol 73 (2003), 862–871, 10.1189/jlb.1202618.
    • (2003) J Leukoc Biol , vol.73 , pp. 862-871
    • Lee, J.Y.1    Kim, N.A.2    Sanford, A.3    Sullivan, K.E.4
  • 91
    • 33646012294 scopus 로고    scopus 로고
    • T helper cell differentiation: regulation by cis elements and epigenetics
    • Lee, G.R., Kim, S.T., Spilianakis, C.G., Fields, P.E., Flavell, R.A., T helper cell differentiation: regulation by cis elements and epigenetics. Immunity 24 (2006), 369–379, 10.1016/j.immuni.2006.03.007.
    • (2006) Immunity , vol.24 , pp. 369-379
    • Lee, G.R.1    Kim, S.T.2    Spilianakis, C.G.3    Fields, P.E.4    Flavell, R.A.5
  • 92
    • 58149251898 scopus 로고    scopus 로고
    • Late developmental plasticity in the T helper 17 lineage
    • Lee, Y.K., Turner, H., Maynard, C.L., Oliver, J.R., Chen, D., Elson, C.O., et al. Late developmental plasticity in the T helper 17 lineage. Immunity 30 (2009), 92–107, 10.1016/j.immuni.2008.11.005.
    • (2009) Immunity , vol.30 , pp. 92-107
    • Lee, Y.K.1    Turner, H.2    Maynard, C.L.3    Oliver, J.R.4    Chen, D.5    Elson, C.O.6
  • 93
    • 77955287968 scopus 로고    scopus 로고
    • Surviving lethal septic shock without fluid resuscitation in a rodent model
    • Li, Y., Liu, B., Fukudome, E.Y., Kochanek, A.R., Finkelstein, R.A., Chong, W., et al. Surviving lethal septic shock without fluid resuscitation in a rodent model. Surgery 148 (2010), 246–254, 10.1016/j.surg.2010.05.003.
    • (2010) Surgery , vol.148 , pp. 246-254
    • Li, Y.1    Liu, B.2    Fukudome, E.Y.3    Kochanek, A.R.4    Finkelstein, R.A.5    Chong, W.6
  • 95
    • 0037934497 scopus 로고    scopus 로고
    • T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells
    • Lugo-Villarino, G., Maldonado-Lopez, R., Possemato, R., Penaranda, C., Glimcher, L.H., T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells. Proc Natl Acad Sci U S A 100 (2003), 7749–7754, 10.1073/pnas.1332767100.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7749-7754
    • Lugo-Villarino, G.1    Maldonado-Lopez, R.2    Possemato, R.3    Penaranda, C.4    Glimcher, L.H.5
  • 96
    • 84877834865 scopus 로고    scopus 로고
    • The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock
    • Lugrin, J., Ciarlo, E., Santos, A., Grandmaison, G., dos Santos, I., Le Roy, D., et al. The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock. Biochim Biophys Acta 1833 (2013), 1498–1510, 10.1016/j.bbamcr.2013.03.004.
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 1498-1510
    • Lugrin, J.1    Ciarlo, E.2    Santos, A.3    Grandmaison, G.4    dos Santos, I.5    Le Roy, D.6
  • 97
    • 84862777909 scopus 로고    scopus 로고
    • Suppression of the antiviral response by an influenza histone mimic
    • Marazzi, I., Ho, J.S.Y., Kim, J., Manicassamy, B., Dewell, S., Albrecht, R.A.,.. Tarakhovsky, A., Suppression of the antiviral response by an influenza histone mimic. Nature 483:7390 (2012), 428–433, 10.1038/nature10892.
    • (2012) Nature , vol.483 , Issue.7390 , pp. 428-433
    • Marazzi, I.1    Ho, J.S.Y.2    Kim, J.3    Manicassamy, B.4    Dewell, S.5    Albrecht, R.A.6    Tarakhovsky, A.7
  • 98
    • 84908314543 scopus 로고    scopus 로고
    • MicroRNAs in the interaction between host and bacterial pathogens
    • Maudet, C., Mano, M., Eulalio, A., MicroRNAs in the interaction between host and bacterial pathogens. FEBS Lett 588:22 (2014), 4140–4147, 10.1016/j.febslet.2014.08.002.
    • (2014) FEBS Lett , vol.588 , Issue.22 , pp. 4140-4147
    • Maudet, C.1    Mano, M.2    Eulalio, A.3
  • 99
    • 70349443224 scopus 로고    scopus 로고
    • Transcriptional control of the inflammatory response
    • Medzhitov, R., Horng, T., Transcriptional control of the inflammatory response. Nat Rev Immunol 9 (2009), 692–703, 10.1038/nri2634.
    • (2009) Nat Rev Immunol , vol.9 , pp. 692-703
    • Medzhitov, R.1    Horng, T.2
  • 100
    • 33846487941 scopus 로고    scopus 로고
    • Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the TF SOX13
    • Melichar, H.J., Narayan, K., Der, S.D., Hiraoka, Y., Gardiol, N., Jeannet, G., et al. Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the TF SOX13. Science 315 (2007), 230–233, 10.1126/science.1135344.
    • (2007) Science , vol.315 , pp. 230-233
    • Melichar, H.J.1    Narayan, K.2    Der, S.D.3    Hiraoka, Y.4    Gardiol, N.5    Jeannet, G.6
  • 101
    • 0037236203 scopus 로고    scopus 로고
    • Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes
    • Messi, M., Giacchetto, I., Nagata, K., Lanzavecchia, A., Natoli, G., Sallusto, F., Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes. Nat Immunol 4 (2003), 78–86, 10.1038/ni872.
    • (2003) Nat Immunol , vol.4 , pp. 78-86
    • Messi, M.1    Giacchetto, I.2    Nagata, K.3    Lanzavecchia, A.4    Natoli, G.5    Sallusto, F.6
  • 102
    • 79953172571 scopus 로고    scopus 로고
    • Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4 + T cell subsets
    • Michalek, R.D., Gerriets, V.A., Jacobs, S.R., Macintyre, A.N., MacIver, N.J., Mason, E.F., et al. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4 + T cell subsets. J Immunol 186 (2011), 3299–3303, 10.4049/jimmunol.1003613.
    • (2011) J Immunol , vol.186 , pp. 3299-3303
    • Michalek, R.D.1    Gerriets, V.A.2    Jacobs, S.R.3    Macintyre, A.N.4    MacIver, N.J.5    Mason, E.F.6
  • 103
    • 84860549923 scopus 로고    scopus 로고
    • Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice
    • Modak, R., Das Mitra, S., Krishnamoorthy, P., Bhat, A., Banerjee, A., Gowsica, B.R., Kundu, T.K., Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice. Epigenetics 7:5 (2012), 492–501, 10.4161/epi.19742.
    • (2012) Epigenetics , vol.7 , Issue.5 , pp. 492-501
    • Modak, R.1    Das Mitra, S.2    Krishnamoorthy, P.3    Bhat, A.4    Banerjee, A.5    Gowsica, B.R.6    Kundu, T.K.7
  • 104
    • 84963637816 scopus 로고    scopus 로고
    • Epigenetic response in mice mastitis: role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection
    • Modak, R., Das Mitra, S., Vasudevan, M., Krishnamoorthy, P., Kumar, M., Bhat, A.V., Kundu, T.K., Epigenetic response in mice mastitis: role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection. Clin Epigenetics, 6(1), 2014, 12, 10.1186/1868-7083-6-12.
    • (2014) Clin Epigenetics , vol.6 , Issue.1 , pp. 12
    • Modak, R.1    Das Mitra, S.2    Vasudevan, M.3    Krishnamoorthy, P.4    Kumar, M.5    Bhat, A.V.6    Kundu, T.K.7
  • 105
    • 80053428068 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors impair antibacterial defenses of macrophages
    • Mombelli, M., Lugrin, J., Rubino, I., Chanson, A.-L., Giddey, M., Calandra, T., et al. Histone deacetylase inhibitors impair antibacterial defenses of macrophages. J Infect Dis 204 (2011), 1367–1374, 10.1093/infdis/jir553.
    • (2011) J Infect Dis , vol.204 , pp. 1367-1374
    • Mombelli, M.1    Lugrin, J.2    Rubino, I.3    Chanson, A.-L.4    Giddey, M.5    Calandra, T.6
  • 106
    • 0029791026 scopus 로고    scopus 로고
    • Sodium valproate, an anticonvulsant drug, stimulates human immunodeficiency virus type 1 replication independently of glutathione levels
    • Moog, C., Kuntz-Simon, G., Caussin-Schwemling, C., Obert, G., Sodium valproate, an anticonvulsant drug, stimulates human immunodeficiency virus type 1 replication independently of glutathione levels. J Gen Virol 77:Pt 9 (1996), 1993–1999.
    • (1996) J Gen Virol , vol.77 , pp. 1993-1999
    • Moog, C.1    Kuntz-Simon, G.2    Caussin-Schwemling, C.3    Obert, G.4
  • 107
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D.M., Edwards, J.P., Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8 (2008), 958–969, 10.1038/nri2448.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 108
    • 82955247088 scopus 로고    scopus 로고
    • Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
    • Mullican, S.E., Gaddis, C.A., Alenghat, T., Nair, M.G., Giacomin, P.R., Everett, L.J.,.. Lazar, M.A., Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev 25:23 (2011), 2480–2488, 10.1101/gad.175950.111.
    • (2011) Genes Dev , vol.25 , Issue.23 , pp. 2480-2488
    • Mullican, S.E.1    Gaddis, C.A.2    Alenghat, T.3    Nair, M.G.4    Giacomin, P.R.5    Everett, L.J.6    Lazar, M.A.7
  • 109
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: nomenclature and experimental guidelines
    • Murray, P.J., Allen, J.E., Biswas, S.K., Fisher, E.A., Gilroy, D.W., Goerdt, S.,.. Wynn, T.A., Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41:1 (2014), 14–20, 10.1016/j.immuni.2014.06.008.
    • (2014) Immunity , vol.41 , Issue.1 , pp. 14-20
    • Murray, P.J.1    Allen, J.E.2    Biswas, S.K.3    Fisher, E.A.4    Gilroy, D.W.5    Goerdt, S.6    Wynn, T.A.7
  • 110
    • 77954928774 scopus 로고    scopus 로고
    • Maintaining cell identity through global control of genomic organization
    • Natoli, G., Maintaining cell identity through global control of genomic organization. Immunity 33:1 (2010), 12–24, 10.1016/j.immuni.2010.07.006.
    • (2010) Immunity , vol.33 , Issue.1 , pp. 12-24
    • Natoli, G.1
  • 111
    • 78651479749 scopus 로고    scopus 로고
    • The genomic landscapes of inflammation
    • Natoli, G., Ghisletti, S., Barozzi, I., The genomic landscapes of inflammation. Genes Dev 25 (2011), 101–106, 10.1101/gad.2018811.
    • (2011) Genes Dev , vol.25 , pp. 101-106
    • Natoli, G.1    Ghisletti, S.2    Barozzi, I.3
  • 112
    • 79956080152 scopus 로고    scopus 로고
    • Trained immunity: a memory for innate host defense
    • Netea, M.G., Quintin, J., van der Meer, J.W.M., Trained immunity: a memory for innate host defense. Cell Host Microbe 9 (2011), 355–361, 10.1016/j.chom.2011.04.006.
    • (2011) Cell Host Microbe , vol.9 , pp. 355-361
    • Netea, M.G.1    Quintin, J.2    van der Meer, J.W.M.3
  • 113
    • 84920476638 scopus 로고    scopus 로고
    • Quantitative proteomics reveals a role for epigenetic reprogramming during human monocyte differentiation
    • Nicholas, D., Tang, H., Zhang, Q., Rudra, J., Xu, F., Langridge, W., et al. Quantitative proteomics reveals a role for epigenetic reprogramming during human monocyte differentiation. Mol Cell Proteomics, 2014, 10.1074/mcp.M113.035089.
    • (2014) Mol Cell Proteomics
    • Nicholas, D.1    Tang, H.2    Zhang, Q.3    Rudra, J.4    Xu, F.5    Langridge, W.6
  • 114
    • 78650806593 scopus 로고    scopus 로고
    • Suppression of inflammation by a synthetic histone mimic
    • Nicodeme, E., Jeffrey, K.L., Schaefer, U., Beinke, S., Dewell, S., Chung, C., et al. Suppression of inflammation by a synthetic histone mimic. Nature 468 (2010), 1119–1123, 10.1038/nature09589.
    • (2010) Nature , vol.468 , pp. 1119-1123
    • Nicodeme, E.1    Jeffrey, K.L.2    Schaefer, U.3    Beinke, S.4    Dewell, S.5    Chung, C.6
  • 115
    • 4344652071 scopus 로고    scopus 로고
    • Early steps of retrovirus replicative cycle
    • Nisole, S., Saïb, A., Early steps of retrovirus replicative cycle. Retrovirology, 1, 2004, 9, 10.1186/1742-4690-1-9.
    • (2004) Retrovirology , vol.1 , pp. 9
    • Nisole, S.1    Saïb, A.2
  • 116
    • 84907203429 scopus 로고    scopus 로고
    • Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection
    • O'Connor, C.M., DiMaggio, P.A., Shenk, T., Garcia, B.A., Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. Mol Cell Proteomics 13:9 (2014), 2399–2410, 10.1074/mcp.M114.039792.
    • (2014) Mol Cell Proteomics , vol.13 , Issue.9 , pp. 2399-2410
    • O'Connor, C.M.1    DiMaggio, P.A.2    Shenk, T.3    Garcia, B.A.4
  • 117
    • 33645989497 scopus 로고    scopus 로고
    • T cell- and B cell-independent adaptive immunity mediated by natural killer cells
    • O'Leary, J.G., Goodarzi, M., Drayton, D.L., von Andrian, U.H., T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat Immunol 7 (2006), 507–516, 10.1038/ni1332.
    • (2006) Nat Immunol , vol.7 , pp. 507-516
    • O'Leary, J.G.1    Goodarzi, M.2    Drayton, D.L.3    von Andrian, U.H.4
  • 118
    • 84872576236 scopus 로고    scopus 로고
    • Metabolism of inflammation limited by AMPK and pseudo-starvation
    • O'Neill, L.A.J., Hardie, D.G., Metabolism of inflammation limited by AMPK and pseudo-starvation. Nature 493 (2013), 346–355, 10.1038/nature11862.
    • (2013) Nature , vol.493 , pp. 346-355
    • O'Neill, L.A.J.1    Hardie, D.G.2
  • 119
    • 84936942449 scopus 로고    scopus 로고
    • Barrier-to-autointegration factor 1 (BAF/BANF1) promotes association of the SETD1A histone methyltransferase with herpes simplex virus immediate-early gene promoters
    • e00345–00315
    • Oh, H.S., Traktman, P., Knipe, D.M., Barrier-to-autointegration factor 1 (BAF/BANF1) promotes association of the SETD1A histone methyltransferase with herpes simplex virus immediate-early gene promoters. mBio, 6(3), 2015, 10.1128/mBio.00345-15 e00345–00315.
    • (2015) mBio , vol.6 , Issue.3
    • Oh, H.S.1    Traktman, P.2    Knipe, D.M.3
  • 120
    • 0141995062 scopus 로고    scopus 로고
    • Chromatin history: our view from the bridge
    • Olins, D.E., Olins, A.L., Chromatin history: our view from the bridge. Nat Rev Mol Cell Biol 4 (2003), 809–814, 10.1038/nrm1225.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 809-814
    • Olins, D.E.1    Olins, A.L.2
  • 121
    • 84872522528 scopus 로고    scopus 로고
    • Latent enhancers activated by stimulation in differentiated cells
    • Ostuni, R., Piccolo, V., Barozzi, I., Polletti, S., Termanini, A., Bonifacio, S.,.. Natoli, G., Latent enhancers activated by stimulation in differentiated cells. Cell 152:1–2 (2013), 157–171, 10.1016/j.cell.2012.12.018.
    • (2013) Cell , vol.152 , Issue.1-2 , pp. 157-171
    • Ostuni, R.1    Piccolo, V.2    Barozzi, I.3    Polletti, S.4    Termanini, A.5    Bonifacio, S.6    Natoli, G.7
  • 123
    • 84907327882 scopus 로고    scopus 로고
    • Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria
    • Papanicolaou, K.N., O'Rourke, B., Foster, D.B., Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria. Front Physiol, 5, 2014, 10.3389/fphys.2014.00301.
    • (2014) Front Physiol , vol.5
    • Papanicolaou, K.N.1    O'Rourke, B.2    Foster, D.B.3
  • 124
    • 84880791239 scopus 로고    scopus 로고
    • SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
    • Park, J., Chen, Y., Tishkoff, D.X., Peng, C., Tan, M., Dai, L., et al. SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell 50 (2013), 919–930, 10.1016/j.molcel.2013.06.001.
    • (2013) Mol Cell , vol.50 , pp. 919-930
    • Park, J.1    Chen, Y.2    Tishkoff, D.X.3    Peng, C.4    Tan, M.5    Dai, L.6
  • 125
    • 33751578866 scopus 로고    scopus 로고
    • TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages
    • Pathak, S.K., Basu, S., Bhattacharyya, A., Pathak, S., Banerjee, A., Basu, J., et al. TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages. J Immunol 177 (2006), 7950–7958, 10.4049/jimmunol.177.11.7950.
    • (2006) J Immunol , vol.177 , pp. 7950-7958
    • Pathak, S.K.1    Basu, S.2    Bhattacharyya, A.3    Pathak, S.4    Banerjee, A.5    Basu, J.6
  • 126
    • 57349090221 scopus 로고    scopus 로고
    • Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency
    • Pearson, R., Kim, Y.K., Hokello, J., Lassen, K., Friedman, J., Tyagi, M., Karn, J., Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency. J Virol 82:24 (2008), 12291–12303.
    • (2008) J Virol , vol.82 , Issue.24 , pp. 12291-12303
    • Pearson, R.1    Kim, Y.K.2    Hokello, J.3    Lassen, K.4    Friedman, J.5    Tyagi, M.6    Karn, J.7
  • 127
  • 128
    • 69749111046 scopus 로고    scopus 로고
    • Panobinostat (LBH589): a novel pan-deacetylase inhibitor with activity in T cell lymphoma
    • Prince, H.M., Bishton, M.J., Panobinostat (LBH589): a novel pan-deacetylase inhibitor with activity in T cell lymphoma. Haematol Meet Rep 3:1 (2009), 33–38.
    • (2009) Haematol Meet Rep , vol.3 , Issue.1 , pp. 33-38
    • Prince, H.M.1    Bishton, M.J.2
  • 129
    • 84865119423 scopus 로고    scopus 로고
    • Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes
    • Quintin, J., Saeed, S., Martens, J.H.A., Giamarellos-Bourboulis, E.J., Ifrim, D.C., Logie, C., et al. Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Cell Host Microbe 12 (2012), 223–232, 10.1016/j.chom.2012.06.006.
    • (2012) Cell Host Microbe , vol.12 , pp. 223-232
    • Quintin, J.1    Saeed, S.2    Martens, J.H.A.3    Giamarellos-Bourboulis, E.J.4    Ifrim, D.C.5    Logie, C.6
  • 130
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • Rada-Iglesias, A., Bajpai, R., Swigut, T., Brugmann, S.A., Flynn, R.A., Wysocka, J., A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470:7333 (2011), 279–283, 10.1038/nature09692.
    • (2011) Nature , vol.470 , Issue.7333 , pp. 279-283
    • Rada-Iglesias, A.1    Bajpai, R.2    Swigut, T.3    Brugmann, S.A.4    Flynn, R.A.5    Wysocka, J.6
  • 131
    • 79959483607 scopus 로고    scopus 로고
    • The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3 ▿
    • Rahman, S., Sowa, M.E., Ottinger, M., Smith, J.A., Shi, Y., Harper, J.W., et al. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3 ▿. Mol Cell Biol 31 (2011), 2641–2652, 10.1128/MCB.01341-10.
    • (2011) Mol Cell Biol , vol.31 , pp. 2641-2652
    • Rahman, S.1    Sowa, M.E.2    Ottinger, M.3    Smith, J.A.4    Shi, Y.5    Harper, J.W.6
  • 132
    • 80054810826 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b
    • Rajaram, M.V.S., Ni, B., Morris, J.D., Brooks, M.N., Carlson, T.K., Bakthavachalu, B.,.. Schlesinger, L.S., Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. Proc Natl Acad Sci 108:42 (2011), 17408–17413, 10.1073/pnas.1112660108.
    • (2011) Proc Natl Acad Sci , vol.108 , Issue.42 , pp. 17408-17413
    • Rajaram, M.V.S.1    Ni, B.2    Morris, J.D.3    Brooks, M.N.4    Carlson, T.K.5    Bakthavachalu, B.6    Schlesinger, L.S.7
  • 133
    • 84878051136 scopus 로고    scopus 로고
    • Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation
    • Rasmussen, T.A., Schmeltz Søgaard, O., Brinkmann, C., Wightman, F., Lewin, S.R., Melchjorsen, J., et al. Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation. Hum Vaccines Immunotherapeutics 9:5 (2013), 993–1001.
    • (2013) Hum Vaccines Immunotherapeutics , vol.9 , Issue.5 , pp. 993-1001
    • Rasmussen, T.A.1    Schmeltz Søgaard, O.2    Brinkmann, C.3    Wightman, F.4    Lewin, S.R.5    Melchjorsen, J.6
  • 134
    • 84911460971 scopus 로고    scopus 로고
    • Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
    • Rasmussen, T.A., Tolstrup, M., Brinkmann, C.R., Olesen, R., Erikstrup, C., Solomon, A., et al. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. Lancet HIV 1:1 (2014), e13–e21.
    • (2014) Lancet HIV , vol.1 , Issue.1 , pp. e13-e21
    • Rasmussen, T.A.1    Tolstrup, M.2    Brinkmann, C.R.3    Olesen, R.4    Erikstrup, C.5    Solomon, A.6
  • 135
    • 84945305044 scopus 로고    scopus 로고
    • Chromatin-bound bacterial effector ankyrin A recruits histone deacetylase 1 and modifies host gene expression
    • Rennoll-Bankert, K.E., Garcia-Garcia, J.C., Sinclair, S.H., Dumler, J.S., Chromatin-bound bacterial effector ankyrin A recruits histone deacetylase 1 and modifies host gene expression. Cell Microbiol 17:11 (2015), 1640–1652, 10.1111/cmi.12461.
    • (2015) Cell Microbiol , vol.17 , Issue.11 , pp. 1640-1652
    • Rennoll-Bankert, K.E.1    Garcia-Garcia, J.C.2    Sinclair, S.H.3    Dumler, J.S.4
  • 136
    • 67650550767 scopus 로고    scopus 로고
    • Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection P. Sommer, ed
    • pp. e6093–19
    • Reuse, S., Calao, M., Kabeya, K., Guiguen, A., Gatot, J.-S., Quivy, V., et al. Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection P. Sommer, ed. PLoS One, 4(6), 2009 pp. e6093–19.
    • (2009) PLoS One , vol.4 , Issue.6
    • Reuse, S.1    Calao, M.2    Kabeya, K.3    Guiguen, A.4    Gatot, J.-S.5    Quivy, V.6
  • 137
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • Robins, H.S., Campregher, P.V., Srivastava, S.K., Wacher, A., Turtle, C.J., Kahsai, O., et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 114 (2009), 4099–4107, 10.1182/blood-2009-04-217604.
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1    Campregher, P.V.2    Srivastava, S.K.3    Wacher, A.4    Turtle, C.J.5    Kahsai, O.6
  • 138
    • 79251554670 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
    • Roger, T., Lugrin, J., Roy, D.L., Goy, G., Mombelli, M., Koessler, T., et al. Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood 117 (2011), 1205–1217, 10.1182/blood-2010-05-284711.
    • (2011) Blood , vol.117 , pp. 1205-1217
    • Roger, T.1    Lugrin, J.2    Roy, D.L.3    Goy, G.4    Mombelli, M.5    Koessler, T.6
  • 139
    • 33750488431 scopus 로고    scopus 로고
    • The genomic landscape of histone modifications in human T cells
    • Roh, T.-Y., Cuddapah, S., Cui, K., Zhao, K., The genomic landscape of histone modifications in human T cells. Proc Natl Acad Sci 103 (2006), 15782–15787.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 15782-15787
    • Roh, T.-Y.1    Cuddapah, S.2    Cui, K.3    Zhao, K.4
  • 140
    • 84876395478 scopus 로고    scopus 로고
    • Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication
    • Rolando, M., Sanulli, S., Rusniok, C., Gomez-Valero, L., Bertholet, C., Sahr, T., et al. Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication. Cell Host Microbe 13 (2013), 395–405, 10.1016/j.chom.2013.03.004.
    • (2013) Cell Host Microbe , vol.13 , pp. 395-405
    • Rolando, M.1    Sanulli, S.2    Rusniok, C.3    Gomez-Valero, L.4    Bertholet, C.5    Sahr, T.6
  • 141
    • 84896979169 scopus 로고    scopus 로고
    • Transcriptional control of early T and B cell developmental choices
    • Rothenberg, E.V., Transcriptional control of early T and B cell developmental choices. Annu Rev Immunol 32 (2014), 283–321, 10.1146/annurev-immunol-032712-100024.
    • (2014) Annu Rev Immunol , vol.32 , pp. 283-321
    • Rothenberg, E.V.1
  • 142
    • 84907483941 scopus 로고    scopus 로고
    • Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
    • Saeed, S., Quintin, J., Kerstens, H.H.D., Rao, N.A., Aghajanirefah, A., Matarese, F., et al. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science, 345, 2014, 1251086, 10.1126/science.1251086.
    • (2014) Science , vol.345 , pp. 1251086
    • Saeed, S.1    Quintin, J.2    Kerstens, H.H.D.3    Rao, N.A.4    Aghajanirefah, A.5    Matarese, F.6
  • 143
    • 77956954197 scopus 로고    scopus 로고
    • The Jmjd3–Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
    • Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Tanaka, Y., Kumagai, Y., et al. The Jmjd3–Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol 11 (2010), 936–944, 10.1038/ni.1920.
    • (2010) Nat Immunol , vol.11 , pp. 936-944
    • Satoh, T.1    Takeuchi, O.2    Vandenbon, A.3    Yasuda, K.4    Tanaka, Y.5    Kumagai, Y.6
  • 146
    • 34547890019 scopus 로고    scopus 로고
    • Functions of site-specific histone acetylation and deacetylation
    • Shahbazian, M.D., Grunstein, M., Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 76 (2007), 75–100, 10.1146/annurev.biochem.76.052705.162114.
    • (2007) Annu Rev Biochem , vol.76 , pp. 75-100
    • Shahbazian, M.D.1    Grunstein, M.2
  • 147
    • 80355146868 scopus 로고    scopus 로고
    • Monocyte recruitment during infection and inflammation
    • Shi, C., Pamer, E.G., Monocyte recruitment during infection and inflammation. Nat Rev Immunol 11 (2011), 762–774, 10.1038/nri3070.
    • (2011) Nat Rev Immunol , vol.11 , pp. 762-774
    • Shi, C.1    Pamer, E.G.2
  • 148
    • 84883548750 scopus 로고    scopus 로고
    • Mitochondrial sirtuins as therapeutic targets for age-related disorders
    • Shih, J., Donmez, G., Mitochondrial sirtuins as therapeutic targets for age-related disorders. Genes Cancer 4:3–4 (2013), 91–96, 10.1177/1947601912474931.
    • (2013) Genes Cancer , vol.4 , Issue.3-4 , pp. 91-96
    • Shih, J.1    Donmez, G.2
  • 149
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 + T cells
    • Siliciano, J.D., et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 + T cells. Nat Med 9:6 (2003), 727–728.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 727-728
    • Siliciano, J.D.1
  • 150
    • 77949971595 scopus 로고    scopus 로고
    • Selective transcription in response to an inflammatory stimulus
    • Smale, S.T., Selective transcription in response to an inflammatory stimulus. Cell 140 (2010), 833–844, 10.1016/j.cell.2010.01.037.
    • (2010) Cell , vol.140 , pp. 833-844
    • Smale, S.T.1
  • 151
    • 84896919030 scopus 로고    scopus 로고
    • Chromatin contributions to the regulation of innate immunity
    • Smale, S.T., Tarakhovsky, A., Natoli, G., Chromatin contributions to the regulation of innate immunity. Annu Rev Immunol 32 (2014), 489–511, 10.1146/annurev-immunol-031210-101303.
    • (2014) Annu Rev Immunol , vol.32 , pp. 489-511
    • Smale, S.T.1    Tarakhovsky, A.2    Natoli, G.3
  • 152
    • 84881490002 scopus 로고    scopus 로고
    • MicroRNAs and bacterial infection
    • Staedel, C., Darfeuille, F., MicroRNAs and bacterial infection. Cell Microbiol 15:9 (2013), 1496–1507, 10.1111/cmi.12159.
    • (2013) Cell Microbiol , vol.15 , Issue.9 , pp. 1496-1507
    • Staedel, C.1    Darfeuille, F.2
  • 153
    • 33747608638 scopus 로고    scopus 로고
    • NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K.D., Boldin, M.P., Chang, K.-J., Baltimore, D., NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci 103:33 (2006), 12481–12486, 10.1073/pnas.0605298103.
    • (2006) Proc Natl Acad Sci , vol.103 , Issue.33 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.-J.3    Baltimore, D.4
  • 155
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Tanuchi, I., Osato, M., Egawa, T., Sunshine, M.J., Bae, S.C., Komori, T., Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111 (2002), 621–633.
    • (2002) Cell , vol.111 , pp. 621-633
    • Tanuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6
  • 156
    • 62449202866 scopus 로고    scopus 로고
    • Preferential generation of follicular B helper T cells from Foxp3 + T cells in gut Peyer's patches
    • Tsuji, M., Komatsu, N., Kawamoto, S., Suzuki, K., Kanagawa, O., Honjo, T., et al. Preferential generation of follicular B helper T cells from Foxp3 + T cells in gut Peyer's patches. Science 323 (2009), 1488–1492, 10.1126/science.1169152.
    • (2009) Science , vol.323 , pp. 1488-1492
    • Tsuji, M.1    Komatsu, N.2    Kawamoto, S.3    Suzuki, K.4    Kanagawa, O.5    Honjo, T.6
  • 157
    • 1542273549 scopus 로고    scopus 로고
    • Macrophages in innate and acquired immunity
    • Twigg, H.L., Macrophages in innate and acquired immunity. Semin Respir Crit Care Med 25 (2004), 21–31, 10.1055/s-2004-822302.
    • (2004) Semin Respir Crit Care Med , vol.25 , pp. 21-31
    • Twigg, H.L.1
  • 158
    • 84891860991 scopus 로고    scopus 로고
    • The many faces of sirtuins: coupling of NAD metabolism, sirtuins and lifespan
    • Verdin, E., The many faces of sirtuins: coupling of NAD metabolism, sirtuins and lifespan. Nat Med 20:1 (2014), 25–27, 10.1038/nm.3447.
    • (2014) Nat Med , vol.20 , Issue.1 , pp. 25-27
    • Verdin, E.1
  • 159
    • 0027258123 scopus 로고
    • Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation
    • Verdin, E., Paras, P., Van Lint, C., Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J 12:8 (1993), 3249–3259.
    • (1993) EMBO J , vol.12 , Issue.8 , pp. 3249-3259
    • Verdin, E.1    Paras, P.2    Van Lint, C.3
  • 160
    • 84875974357 scopus 로고    scopus 로고
    • Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects
    • Vishwakarma, S., Iyer, L.R., Muley, M., Singh, P.K., Shastry, A., Saxena, A.,.. Narayanan, S., Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects. Int Immunopharmacol 16:1 (2013), 72–78, 10.1016/j.intimp.2013.03.016.
    • (2013) Int Immunopharmacol , vol.16 , Issue.1 , pp. 72-78
    • Vishwakarma, S.1    Iyer, L.R.2    Muley, M.3    Singh, P.K.4    Shastry, A.5    Saxena, A.6    Narayanan, S.7
  • 161
    • 17844362500 scopus 로고    scopus 로고
    • Mycobacteria inhibition of IFN-γ induced HLA-DR gene expression by up-regulating histone deacetylation at the promoter region in human THP-1 monocytic cells
    • Wang, Y., Curry, H.M., Zwilling, B.S., Lafuse, W.P., Mycobacteria inhibition of IFN-γ induced HLA-DR gene expression by up-regulating histone deacetylation at the promoter region in human THP-1 monocytic cells. J Immunol 174:9 (2005), 5687–5694, 10.4049/jimmunol.174.9.5687.
    • (2005) J Immunol , vol.174 , Issue.9 , pp. 5687-5694
    • Wang, Y.1    Curry, H.M.2    Zwilling, B.S.3    Lafuse, W.P.4
  • 162
    • 67650072604 scopus 로고    scopus 로고
    • Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing
    • Webby, C.J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., et al. Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing. Science 325 (2009), 90–93, 10.1126/science.1175865.
    • (2009) Science , vol.325 , pp. 90-93
    • Webby, C.J.1    Wolf, A.2    Gromak, N.3    Dreger, M.4    Kramer, H.5    Kessler, B.6
  • 163
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 + T cells
    • Wei, G., Wei, L., Zhu, J., Zang, C., Hu-Li, J., Yao, Z., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 + T cells. Immunity 30 (2009), 155–167, 10.1016/j.immuni.2008.12.009.
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6
  • 164
    • 0035221154 scopus 로고    scopus 로고
    • Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event
    • Weinmann, A.S., Mitchell, D.M., Sanjabi, S., Bradley, M.N., Hoffmann, A., Liou, H.C., et al. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat Immunol 2 (2001), 51–57, 10.1038/83168.
    • (2001) Nat Immunol , vol.2 , pp. 51-57
    • Weinmann, A.S.1    Mitchell, D.M.2    Sanjabi, S.3    Bradley, M.N.4    Hoffmann, A.5    Liou, H.C.6
  • 166
    • 52649167186 scopus 로고    scopus 로고
    • Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis
    • Wheeler, D.S., Lahni, P.M., Denenberg, A.G., Poynter, S.E., Wong, H.R., Cook, J.A., et al. Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis. Shock 30 (2008), 267–273, 10.1097/shk.0b013e318162c190.
    • (2008) Shock , vol.30 , pp. 267-273
    • Wheeler, D.S.1    Lahni, P.M.2    Denenberg, A.G.3    Poynter, S.E.4    Wong, H.R.5    Cook, J.A.6
  • 167
    • 4744359117 scopus 로고    scopus 로고
    • Prostratin antagonizes HIV latency by activating NF-kappaB
    • Williams, S.A., Chen, L.-F., Kwon, H., Fenard, D., Bisgrove, D., Verdin, E., et al. Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem 279:40 (2004), 42008–42017.
    • (2004) J Biol Chem , vol.279 , Issue.40 , pp. 42008-42017
    • Williams, S.A.1    Chen, L.-F.2    Kwon, H.3    Fenard, D.4    Bisgrove, D.5    Verdin, E.6
  • 168
    • 0031022397 scopus 로고    scopus 로고
    • Cell type-dependent effect of sodium valproate on human immunodeficiency virus type 1 replication in vitro
    • Witvrouw, M., et al. Cell type-dependent effect of sodium valproate on human immunodeficiency virus type 1 replication in vitro. AIDS Res Hum Retrovir 13:2 (1997), 187–192.
    • (1997) AIDS Res Hum Retrovir , vol.13 , Issue.2 , pp. 187-192
    • Witvrouw, M.1
  • 169
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: regulatory T cells induce CD4 + CD25-Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
    • Xu, L., Kitani, A., Fuss, I., Strober, W., Cutting edge: regulatory T cells induce CD4 + CD25-Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol 1950:178 (2007), 6725–6729.
    • (2007) J Immunol , vol.1950 , Issue.178 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 170
    • 84881510716 scopus 로고    scopus 로고
    • Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce
    • Yáñez, A., Hassanzadeh-Kiabi, N., Ng, M.Y., Megías, J., Subramanian, A., Liu, G.Y., et al. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol 43 (2013), 2114–2125, 10.1002/eji.201343403.
    • (2013) Eur J Immunol , vol.43 , pp. 2114-2125
    • Yáñez, A.1    Hassanzadeh-Kiabi, N.2    Ng, M.Y.3    Megías, J.4    Subramanian, A.5    Liu, G.Y.6
  • 171
    • 37849048599 scopus 로고    scopus 로고
    • T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
    • Yang, X.O., Pappu, B.P., Nurieva, R., Akimzhanov, A., Kang, H.S., Chung, Y., et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28 (2008), 29–39, 10.1016/j.immuni.2007.11.016.
    • (2008) Immunity , vol.28 , pp. 29-39
    • Yang, X.O.1    Pappu, B.P.2    Nurieva, R.3    Akimzhanov, A.4    Kang, H.S.5    Chung, Y.6
  • 172
    • 84947998571 scopus 로고    scopus 로고
    • Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3
    • Yaseen, I., Kaur, P., Nandicoori, V.K., Khosla, S., Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3. Nat Commun, 6, 2015, 8922, 10.1038/ncomms9922.
    • (2015) Nat Commun , vol.6 , pp. 8922
    • Yaseen, I.1    Kaur, P.2    Nandicoori, V.K.3    Khosla, S.4
  • 173
    • 34447560071 scopus 로고    scopus 로고
    • Function of RIG-I-like receptors in antiviral innate immunity
    • Yoneyama, M., Fujita, T., Function of RIG-I-like receptors in antiviral innate immunity. J Biol Chem 282 (2007), 15315–15318, 10.1074/jbc.R700007200.
    • (2007) J Biol Chem , vol.282 , pp. 15315-15318
    • Yoneyama, M.1    Fujita, T.2
  • 174
    • 56649120601 scopus 로고    scopus 로고
    • miR-21 plays a pivotal role in gastric cancer pathogenesis and progression
    • Zhang, Z., Li, Z., Gao, C., Chen, P., Chen, J., Liu, W.,.. Lu, H., miR-21 plays a pivotal role in gastric cancer pathogenesis and progression. Lab Investig 88:12 (2008), 1358–1366, 10.1038/labinvest.2008.94.
    • (2008) Lab Investig , vol.88 , Issue.12 , pp. 1358-1366
    • Zhang, Z.1    Li, Z.2    Gao, C.3    Chen, P.4    Chen, J.5    Liu, W.6    Lu, H.7
  • 175
    • 84904262333 scopus 로고    scopus 로고
    • Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model
    • Zhao, T., Li, Y., Liu, B., Halaweish, I., Mazitschek, R., Alam, H.B., Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model. J Surg Res 190 (2014), 647–654, 10.1016/j.jss.2014.01.056.
    • (2014) J Surg Res , vol.190 , pp. 647-654
    • Zhao, T.1    Li, Y.2    Liu, B.3    Halaweish, I.4    Mazitschek, R.5    Alam, H.B.6
  • 176
    • 0035190986 scopus 로고    scopus 로고
    • Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage
    • Zou, Y.-R., Sunshine, M.-J., Taniuchi, I., Hatam, F., Killeen, N., Littman, D.R., Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage. Nat Genet 29 (2001), 332–336, 10.1038/ng750.
    • (2001) Nat Genet , vol.29 , pp. 332-336
    • Zou, Y.-R.1    Sunshine, M.-J.2    Taniuchi, I.3    Hatam, F.4    Killeen, N.5    Littman, D.R.6


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