The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages

PLoS ONE

Volumn 5, Issue 1, 2010, Pages

  Daigneault, Marc ^a   Preston, Julie A ^a   Marriott, Helen M ^a   Whyte, Moira K B ^a   Dockrell, David H ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN MCL 1; TOLL LIKE RECEPTOR 2;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; LYSOSOME; MACROPHAGE; MITOCHONDRION; MONOCYTE; PHAGOCYTOSIS;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; CYTOKINES; HUMANS; LYSOSOMES; MACROPHAGES; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MONOCYTES; NITRIC OXIDE; PHAGOCYTOSIS; TETRADECANOYLPHORBOL ACETATE;

EID: 77649267205     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008668     Document Type: Article

References (57)

1. Gordon S, Taylor PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5: 953-964.
2. Murphy J, Summer R, Wilson AA, Kotton DN, Fine A (2008) The prolonged life-span of alveolar macrophages. Am J Respir Cell Mol Biol 38: 380-385.
3. van oud Alblas AB, van Furth R (1979) Origin, Kinetics, and characteristics of pulmonary macrophages in the normal steady state. J Exp Med 149: 1504-1518.
4. Landsman L, Jung S (2007) Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J Immunol 179: 3488-3494.
5. Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8: 958-969.
6. Gordon S (2007) The macrophage: past, present and future. Eur J Immunol 37 Suppl 1: S9-17.
7. Gordon SB, Irving GR, Lawson RA, Lee ME, Read RC (2000) Intracellular trafficking and killing of Streptococcus pneumoniae by human alveolar macrophages are influenced by opsonins. Infect Immun 68: 2286-2293.
8. Murao S, Gemmell MA, Callaham MF, Anderson NL, Huberman E (1983) Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1,25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate. Cancer Res 43: 4989-4996.
9. Olsson I, Gullberg U, Ivhed I, Nilsson K (1983) Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1 alpha,25-dihydroxycholecalciferol. Cancer Res 43: 5862-5867.
10. Fleit HB, Kobasiuk CD (1991) The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII. J Leukoc Biol 49: 556-565.
11. Kohro T, Tanaka T, Murakami T, Wada Y, Aburatani H, et al. (2004) A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage. J Atheroscler Thromb 11: 88-97.
12. Park EK, Jung HS, Yang HI, Yoo MC, Kim C, et al. (2007) Optimized THP-1 differentiation is required for the detection of responses to weak stimuli. Inflamm Res 56: 45-50.
13. Collins SJ (1987) The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 70: 1233-1244.
14. Rovera G, O'Brien TG, Diamond L (1979) Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. Science 204: 868-870.
15. Schwende H, Fitzke E, Ambs P, Dieter P (1996) Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3. J Leukoc Biol 59: 555-561.
16. Gantner F, Kupferschmidt R, Schudt C, Wendel A, Hatzelmann A (1997) In vitro differentiation of human monocytes to macrophages: change of PDE profile and its relationship to suppression of tumour necrosis factor-alpha release by PDE inhibitors. Br J Pharmacol 121: 221-231.
17. Dockrell DH, Lee M, Lynch DH, Read RC (2001) Immunemediated phagocytosis and killing of Streptococcus pneumoniae are associated with direct and bystander macrophage apoptosis. J Infect Dis 184: 713-722.
18. Marriott HM, Ali F, Read RC, Mitchell TJ, Whyte MK, et al. (2004) Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection. FASEB J 18: 1126-1128.
19. Vandivier RW, Fadok VA, Hoffmann PR, Bratton DL, Penvari C, et al. (2002) Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis. The Journal of Clinical Investigation 109: 661-670.
20. Marriott HM, Bingle CD, Read RC, Braley KE, Kroemer G, et al. (2005) Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance. J Clin Invest 115: 359-368.
21. Sokol RJ, Hudson G, James NT, Frost IJ, Wales J (1987) Human macrophage development: a morphometric study. J Anat 151: 27-35.
22. Bainton DF (1980) The macrophage. pp 1-25.
23. McCullough KC, Basta S, Knotig S, Gerber H, Schaffner R, et al. (1999) Intermediate stages in monocyte-macrophage differentiation modulate phenotype and susceptibility to virus infection. Immunology 98: 203-212.
24. Kradin RL, McCarthy KM, Preffer FI, Schneeberger EE (1986) Flowcytometric and ultrastructural analysis of alveolar macrophage maturation. J Leukoc Biol 40: 407-417.
25. van Haarst JM, Hoogsteden HC, de Wit HJ, Verhoeven GT, Havenith CE, et al. (1994) Dendritic cells and their precursors isolated from human bronchoalveolar lavage: immunocytologic and functional properties. Am J Respir Cell Mol Biol 11: 344-350.
26. Macouillard-Poulletier de G, Belaud-Rotureau MA, Voisin P, Leducq N, Belloc F, et al. (1998) Flow cytometric analysis of mitochondrial activity in situ: application to acetylceramide-induced mitochondrial swelling and apoptosis. Cytometry 33: 333-339.
27. Cohn ZA, Benson B (1965) The Differentiation of Mononuclear Phagocytes. Morphology, Cytochemistry, and Biochemistry. J Exp Med 121: 153-170.
28. Steinbach F, Thiele B (1994) Phenotypic investigation of mononuclear phagocytes by flow cytometry. J Immunol Methods 174: 109-122.
29. Henning LN, Azad AK, Parsa KV, Crowther JE, Tridandapani S, et al. (2008) Pulmonary surfactant protein A regulates TLR expression and activity in human macrophages. J Immunol 180: 7847-7858.
30. Liu H, Perlman H, Pagliari LJ, Pope RM (2001) Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation. J Exp Med 194: 113-126.
31. Munn DH, Beall AC, Song D, Wrenn RW, Throckmorton DC (1995) Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon gamma. J Exp Med 181: 127-136.
32. Wewers MD, Rennard SI, Hance AJ, Bitterman PB, Crystal RG (1984) Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1. J Clin Invest 74: 2208-2218.
33. MacMicking J, Xie QW, Nathan C (1997) Nitric oxide and macrophage function. Annu Rev Immunol 15: 323-350.
34. Heo SK, Ju SA, Lee SC, Park SM, Choe SY, et al. (2006) LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM. J Leukoc Biol 79: 330-338.
35. Pham TN, Brown BL, Dobson PR, Richardson VJ (2003) Protein kinase C-eta (PKC-eta) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells. Nitric Oxide 9: 123-134.
36. Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, et al. (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25: 677-686.
37. Stein M, Keshav S, Harris N, Gordon S (1992) Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 176: 287-292.
38. Berges C, Naujokat C, Tinapp S, Wieczorek H, Hoh A, et al. (2005) A cell line model for the differentiation of human dendritic cells. Biochem Biophys Res Commun 333: 896-907.
39. Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, et al. (2005) Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 175: 342-349.
40. Geissmann F, Jung S, Littman DR (2003) Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19: 71-82.
41. Desjardins M, Huber LA, Parton RG, Griffiths G (1994) Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J Cell Biol 124: 677-688.
42. Toyomura T, Murata Y, Yamamoto A, Oka T, Sun-Wada GH, et al. (2003) From lysosomes to the plasma membrane: localization of vacuolar-type H+ - ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem 278: 22023-22030.
43. Pitt A, Mayorga LS, Stahl PD, Schwartz AL (1992) Alterations in the protein composition of maturing phagosomes. J Clin Invest 90: 1978-1983.
44. Hackam DJ, Rotstein OD, Zhang WJ, Demaurex N, Woodside M, et al. (1997) Regulation of phagosomal acidification. Differential targeting of Na+/H+ exchangers, Na+/K+-ATPases, and vacuolar-type H+-atpases. J Biol Chem 272: 29810-29820.
45. Cohn ZA, Fedorko ME, Hirsch JG (1966) The in vitro differentiation of mononuclear phagocytes. V. The formation of macrophage lysosomes. J Exp Med 123: 757-766.
46. Nichols BA, Bainton DF, Farquhar MG (1971) Differentiation of monocytes. Origin, nature, and fate of their azurophil granules. J Cell Biol 50: 498-515.
47. Burchett SK, Weaver WM, Westall JA, Larsen A, Kronheim S, et al. (1988) Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes. J Immunol 140: 3473-3481.
48. Smith SJ, Fenwick PS, Nicholson AG, Kirschenbaum F, Finney-Hayward TK, et al. (2006) Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages. Br J Pharmacol 149: 393-404.
49. Gessani S, Testa U, Varano B, Di Marzio P, Borghi P, et al. (1993) Enhanced production of LPS-induced cytokines during differentiation of human monocytes to macrophages. Role of LPS receptors. J Immunol 151: 3758-3766.
50. Nahori MA, Fournie-Amazouz E, Que-Gewirth NS, Balloy V, Chignard M, et al. (2005) Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells. J Immunol 175: 6022-6031.
51. Lepe-Zuniga JL, Klostergaard J (1990) Tolerance to endotoxin in vitro: independent regulation of interleukin-1, tumor necrosis factor and interferon alpha production during in vitro differentiation of human monocytes. Lymphokine Res 9: 309-319.
52. Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, et al. (2008) Differential requirement for the activation of the inflammasome for processing and release of IL-1{beta} in monocytes and macrophages. Blood.
53. Surewicz K, Aung H, Kanost RA, Jones L, Hejal R, et al. (2004) The differential interaction of p38 MAP kinase and tumor necrosis factor-alpha in human alveolar macrophages and monocytes induced by Mycobacterium tuberculois. Cell Immunol 228: 34-41.
54. Hume DA (2008) Macrophages as APC and the dendritic cell myth. J Immunol 181: 5829-5835.
55. Mangan DF, Welch GR, Wahl SM (1991) Lipopolysaccharide, tumor necrosis factor-alpha, and IL-1 beta prevent programmed cell death (apoptosis) in human peripheral blood monocytes. J Immunol 146: 1541-1546.
56. Perlman H, Pagliari LJ, Georganas C, Mano T, Walsh K, et al. (1999) FLICEinhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. J Exp Med 190: 1679-1688.
57. Sabroe I, Read RC, Whyte MK, Dockrell DH, Vogel SN, et al. (2003) Toll-like receptors in health and disease: complex questions remain. J Immunol 171: 1630-1635.