Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum

PLoS Pathogens

Volumn 5, Issue 6, 2009, Pages

  Garcia Garcia, Jose C ^a   Barat, Nicole C ^a   Trembley, Sarah J ^a   Dumler, J Stephen ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; SMALL INTERFERING RNA; HDAC1 PROTEIN, HUMAN; HISTONE DEACETYLASE;

ACETYLATION; ANAPLASMA PHAGOCYTOPHILUM; ARTICLE; BACTERIAL INFECTION; BACTERIAL SURVIVAL; CHROMATIN STRUCTURE; DOWN REGULATION; EPIGENETICS; GENE SILENCING; GENETIC TRANSCRIPTION; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN GRANULOCYTIC ANAPLASMOSIS; LEUKEMIA CELL LINE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION; CHEMISTRY; CHROMATIN; EHRLICHIOSIS; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; TUMOR CELL LINE;

ANAPLASMA PHAGOCYTOPHILUM; BACTERIA (MICROORGANISMS);

ANAPLASMA PHAGOCYTOPHILUM; CELL LINE, TUMOR; CHROMATIN; DATA INTERPRETATION, STATISTICAL; EHRLICHIOSIS; GENE EXPRESSION REGULATION; GENE SILENCING; HISTONE DEACETYLASES; HOST-PATHOGEN INTERACTIONS; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 67650886021     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000488     Document Type: Article

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