Trained immunity or tolerance: Opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors

Clinical and Vaccine Immunology

Volumn 21, Issue 4, 2014, Pages 534-545

  Ifrim, Daniela C ^a   Quintin, Jessica ^a   Joosten, Leo A B ^a   Jacobs, Cor ^a   Jansen, Trees ^a   Jacobs, Liesbeth ^a   Gow, Neil A R ^b   Williams, David L ^c   Van Der Meer, Jos W M ^a   Netea, Mihai G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c East Tennessee State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; CD11B ANTIGEN; CD14 ANTIGEN; CD209 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; FLAGELLIN; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PATTERN RECOGNITION RECEPTOR; PROTEIN KINASE SYK; STRESS ACTIVATED PROTEIN KINASE; BACTERIAL ANTIGEN; CYTOKINE; VIRUS ANTIGEN;

ARTICLE; CELL FATE; CELL SHAPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOLOGICAL TOLERANCE; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRAINED IMMUNITY; BACTERIA; CANDIDA ALBICANS; IMMUNOLOGY; METABOLISM; SECRETION (PROCESS); VIRUS;

ANTIGENS, BACTERIAL; ANTIGENS, VIRAL; BACTERIA; CANDIDA ALBICANS; CYTOKINES; HUMANS; IMMUNE TOLERANCE; MONOCYTES; RECEPTORS, PATTERN RECOGNITION; VIRUSES;

EID: 84895800375     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00688-13     Document Type: Article

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