Mitochondrial Sirtuins as Therapeutic Targets for Age-Related Disorders

Genes and Cancer

Volumn 4, Issue 3-4, 2013, Pages 91-96

  Shih, Jennifer ^a   Donmez, Gizem ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

aging; cancer; metabolic syndrome; mitochondria; neurodegeneration; sirtuins; therapeutic targets

Indexed keywords

2 OXOGLUTARIC ACID; ACETYL COENZYME A SYNTHETASE; CARBAMOYL PHOSPHATE SYNTHASE; GLUTAMATE DEHYDROGENASE; LACTIC ACID; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SIRTUIN; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5;

CANCER GROWTH; CATABOLISM; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CITRIC ACID CYCLE; DEACETYLATION; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME REGULATION; FATTY ACID OXIDATION; GERIATRIC DISORDER; GLYCOLYSIS; HUMAN; INSULIN RELEASE; LIPID DIET; MALIGNANT NEOPLASTIC DISEASE; METABOLIC REGULATION; METABOLIC SYNDROME X; MITOCHONDRION; NERVE DEGENERATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; UREA CYCLE;

EID: 84883548750     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: 10.1177/1947601912474931     Document Type: Review

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