HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages

Journal of Immunology

Volumn 193, Issue 3, 2014, Pages 1333-1343

  Ha, Soon Duck ^a   Han, Chae Young ^a   Reid, Chantelle ^a   Kim, Sung Ouk ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANACARDIC ACID; ANTHRAX TOXIN; AZACITIDINE; E1A ASSOCIATED P300 PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE 6 SPECIFIC INHIBITOR; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H3 LYSINE 27; INTERLEUKIN 1BETA CONVERTING ENZYME; MOCETINOSTAT; PANOBINOSTAT; PROTEIN BNIP3; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TOZASERTIB; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BNIP3 GENE; BNIP3L GENE; CELL POPULATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INDUCTION; ENZYME INHIBITION; EPIGENETIC REPROGRAMMING; EPIGENETICS; GENE; GENE EXPRESSION REGULATION; GENETIC REGULATION; GENETIC TRANSCRIPTION; HDAC8 GENE; HISTONE ACETYLATION; INDUCED RESISTANCE; MACROPHAGE; MITOCHONDRIAL DEATH GENE; MITOCHONDRIAL GENE; MLN64 GENE; MURINAE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PYROPTOSIS; SENSITIZATION; TOXIN INDUCED RESISTANCE;

ANIMALS; ANTIGENS, BACTERIAL; APOPTOSIS; BACTERIAL TOXINS; BONE MARROW CELLS; CELL LINE; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; EPIGENOMICS; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; INDOLES; MACROPHAGES; MICE; MICE, 129 STRAIN; MITOCHONDRIA; REPRESSOR PROTEINS;

EID: 84906086839     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400420     Document Type: Article

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