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Volumn 32, Issue , 2014, Pages 489-511

Chromatin contributions to the regulation of innate immunity

Author keywords

Chromatin; Epigenetics; Innate immunity; Macrophages; Transcription

Indexed keywords

CYTOKINE; TRANSCRIPTION FACTOR;

EID: 84896919030     PISSN: 07320582     EISSN: 15453278     Source Type: Book Series    
DOI: 10.1146/annurev-immunol-031210-101303     Document Type: Review
Times cited : (149)

References (146)
  • 1
    • 0031050034 scopus 로고    scopus 로고
    • Innate immunity: Impact on the adaptive immune system
    • Medzhitov R, Janeway CA Jr. 1997. Innate immunity: impact on the adaptive immune system. Curr. Opin. Immunol. 9:4-9
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 4-9
    • Medzhitov, R.1    Janeway, Jr.C.A.2
  • 2
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov R, Janeway CA Jr. 1997. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91:295-98
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway, Jr.C.A.2
  • 3
    • 79955746123 scopus 로고    scopus 로고
    • The control of adaptive immune responses by the innate immune system
    • Schenten D, Medzhitov R. 2011. The control of adaptive immune responses by the innate immune system. Adv. Immunol. 109:87-124
    • (2011) Adv. Immunol. , vol.109 , pp. 87-124
    • Schenten, D.1    Medzhitov, R.2
  • 4
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA Jr. 1989. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54(Pt. 1):1-13
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , Issue.PART. 1 , pp. 1-13
    • Janeway, Jr.C.A.1
  • 5
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lamaitre B, Nicolas E, Michaut L, Reichhart JM,Hoffmann JA. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973-83
    • (1996) Cell , vol.86 , pp. 973-983
    • Lamaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 6
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388:394-97
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, Jr.C.A.3
  • 7
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O, Akira S. 2010. Pattern recognition receptors and inflammation. Cell 140:805-20
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 8
    • 78751560494 scopus 로고    scopus 로고
    • Pathogen recognition by the innate immune system
    • Kumar H, Kawai T, Akira S. 2011. Pathogen recognition by the innate immune system. Int. Rev. Immunol. 30:16-34
    • (2011) Int. Rev. Immunol. , vol.30 , pp. 16-34
    • Kumar, H.1    Kawai, T.2    Akira, S.3
  • 9
    • 70349443224 scopus 로고    scopus 로고
    • Transcriptional control of the inflammatory response
    • Medzhitov R, Horng T. 2009. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9:692-703
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 692-703
    • Medzhitov, R.1    Horng, T.2
  • 10
    • 77949971595 scopus 로고    scopus 로고
    • Selective transcription in response to an inflammatory stimulus
    • Smale ST. 2010. Selective transcription in response to an inflammatory stimulus. Cell 140:833-44
    • (2010) Cell , vol.140 , pp. 833-844
    • Smale, S.T.1
  • 11
    • 77954928774 scopus 로고    scopus 로고
    • Maintaining cell identity through global control of genomic organization
    • Natoli G. 2010. Maintaining cell identity through global control of genomic organization. Immunity 33:12-24
    • (2010) Immunity , vol.33 , pp. 12-24
    • Natoli, G.1
  • 12
    • 78651479749 scopus 로고    scopus 로고
    • The genomic landscapes of inflammation
    • Natoli G, Ghisletti S, Barozzi I. 2011. The genomic landscapes of inflammation. Genes Dev. 25:101-6
    • (2011) Genes Dev. , vol.25 , pp. 101-106
    • Natoli, G.1    Ghisletti, S.2    Barozzi, I.3
  • 13
    • 84857052421 scopus 로고    scopus 로고
    • Transcriptional regulation in the innate immune system
    • Smale ST. 2012. Transcriptional regulation in the innate immune system. Curr. Opin. Immunol. 24:51-57
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 51-57
    • Smale, S.T.1
  • 14
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: New mechanisms, molecules, and clinical significance
    • Biswas SK, Lopez-Collazo E. 2009. Endotoxin tolerance: new mechanisms, molecules, and clinical significance. Trends Immunol. 30:475-87
    • (2009) Trends Immunol. , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 15
    • 84880815366 scopus 로고    scopus 로고
    • Short-termmemory of danger signals and environmental stimuli in immune cells
    • Monticelli S, Natoli G. 2013. Short-termmemory of danger signals and environmental stimuli in immune cells. Nat. Immunol. 14:777-84
    • (2013) Nat. Immunol. , vol.14 , pp. 777-784
    • Monticelli, S.1    Natoli, G.2
  • 16
    • 55149092303 scopus 로고    scopus 로고
    • Regulation of interleukin-12/interleukin- 23 production and the T-helper 17 response in humans
    • Lyakh L, Trinchieri G, Provezza L, Carra G, Gerosa F. 2008. Regulation of interleukin-12/interleukin- 23 production and the T-helper 17 response in humans. Immunol. Rev. 226:112-31
    • (2008) Immunol. Rev. , vol.226 , pp. 112-131
    • Lyakh, L.1    Trinchieri, G.2    Provezza, L.3    Carra, G.4    Gerosa, F.5
  • 17
    • 84857389911 scopus 로고    scopus 로고
    • The c-Rel transcription factor in development and disease
    • Gilmore TD, Gerondakis S. 2011. The c-Rel transcription factor in development and disease. Genes Cancer 2:695-711
    • (2011) Genes Cancer , vol.2 , pp. 695-711
    • Gilmore, T.D.1    Gerondakis, S.2
  • 18
    • 84858720808 scopus 로고    scopus 로고
    • Dimer-specific regulatorymechanisms within theNF-κBfamily of transcription factors
    • Smale ST. 2012. Dimer-specific regulatorymechanisms within theNF-κBfamily of transcription factors. Immunol. Rev. 246:193-204
    • (2012) Immunol. Rev. , vol.246 , pp. 193-204
    • Smale, S.T.1
  • 19
    • 33847334699 scopus 로고    scopus 로고
    • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
    • Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, et al. 2007. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet. 39:311-18
    • (2007) Nat. Genet. , vol.39 , pp. 311-318
    • Heintzman, N.D.1    Stuart, R.K.2    Hon, G.3    Fu, Y.4    Ching, C.W.5
  • 20
    • 82955198464 scopus 로고    scopus 로고
    • Recognition of enhancer elementspecific histone methylation by TIP60 in transcriptional activation
    • Jeong KW, Kim K, Situ AJ, Ullmer TS, An W, Stallcup MR. 2011. Recognition of enhancer elementspecific histone methylation by TIP60 in transcriptional activation. Nat. Struct. Mol. Biol. 18:1358-65
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 1358-1365
    • Jeong, K.W.1    Kim, K.2    Situ, A.J.3    Ullmer, T.S.4    An, W.5    Stallcup, M.R.6
  • 23
    • 84872522528 scopus 로고    scopus 로고
    • Latent enhancers activated by stimulation in differentiated cells
    • Otsuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, et al. 2013. Latent enhancers activated by stimulation in differentiated cells. Cell 152:157-71
    • (2013) Cell , vol.152 , pp. 157-171
    • Otsuni, R.1    Piccolo, V.2    Barozzi, I.3    Polletti, S.4    Termanini, A.5
  • 24
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, et al. 2009. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459:108-12
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5
  • 25
    • 79961215084 scopus 로고    scopus 로고
    • Life and death of transcriptional co-Activator p300
    • Chen J, Li Q. 2011. Life and death of transcriptional co-Activator p300. Epigenetics 6:957-61
    • (2011) Epigenetics , vol.6 , pp. 957-961
    • Chen, J.1    Li, Q.2
  • 26
    • 60149091656 scopus 로고    scopus 로고
    • ChIP-seq accurately predicts tissue-specific activity of enhancers
    • Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, et al. 2009. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457:854-58
    • (2009) Nature , vol.457 , pp. 854-858
    • Visel, A.1    Blow, M.J.2    Li, Z.3    Zhang, T.4    Akiyama, J.A.5
  • 27
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, et al. 2010. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32:317-28
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1    Barozzi, I.2    Mietton, F.3    Polletti, S.4    De Santa, F.5
  • 28
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott EW, Simon MC, Anastasi J, Singh H. 1994. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265:1573-77
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 29
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineagedetermining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz S, Benner C, Spann N, Bertolino E, Lin YC, et al. 2010. Simple combinations of lineagedetermining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38:576-89
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5
  • 30
    • 0034717335 scopus 로고    scopus 로고
    • Regulation of B lymphocyte and macrophage development by graded expression of PU.1
    • DeKoter RP, Singh H. 2000. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288:1439-41
    • (2000) Science , vol.288 , pp. 1439-1441
    • Dekoter, R.P.1    Singh, H.2
  • 31
    • 0029767664 scopus 로고    scopus 로고
    • Hepatic specification of the gut endoderm in vitro: Cell signaling and transcriptional control
    • Gualdi R, Bossard P, Zheng M, Hamada Y, Coleman JR, Zaret KS. 1996. Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control. Genes Dev. 10:1670-82
    • (1996) Genes Dev. , vol.10 , pp. 1670-1682
    • Gualdi, R.1    Bossard, P.2    Zheng, M.3    Hamada, Y.4    Coleman, J.R.5    Zaret, K.S.6
  • 32
    • 77956648493 scopus 로고    scopus 로고
    • Pioneer factors in embryonic stem cells and differentiation
    • Smale ST. 2010. Pioneer factors in embryonic stem cells and differentiation. Curr. Opin. Genet. Dev. 20:519-26
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 519-526
    • Smale, S.T.1
  • 33
    • 80455144479 scopus 로고    scopus 로고
    • Pioneer transcription factors: Establishing competence for gene expression
    • Zaret KS, Carroll JS. 2011. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25:2227-41
    • (2011) Genes Dev. , vol.25 , pp. 2227-2241
    • Zaret, K.S.1    Carroll, J.S.2
  • 34
    • 34547635650 scopus 로고    scopus 로고
    • Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells
    • Xu J, Pope SD, Jazirehi AR, Attema JL, Papathanasiou P, et al. 2007. Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc. Natl. Acad. Sci. USA 104:12377-82
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 12377-12382
    • Xu, J.1    Pope, S.D.2    Jazirehi, A.R.3    Attema, J.L.4    Papathanasiou, P.5
  • 35
    • 72849110608 scopus 로고    scopus 로고
    • Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic stem and induced pluripotent stem cells
    • Xu J, Watts JA, Pope SD, Gadue P, Kamps M, et al. 2009. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic stem and induced pluripotent stem cells. Genes Dev. 23:2824-38
    • (2009) Genes Dev. , vol.23 , pp. 2824-2838
    • Xu, J.1    Watts, J.A.2    Pope, S.D.3    Gadue, P.4    Kamps, M.5
  • 36
    • 84855297335 scopus 로고    scopus 로고
    • A decade of 3C technologies: Insights into nuclear organization
    • de Wit E, de Laat W. 2012. A decade of 3C technologies: insights into nuclear organization. Genes Dev. 26:11-24
    • (2012) Genes Dev. , vol.26 , pp. 11-24
    • De Wit, E.1    De Laat, W.2
  • 37
    • 77952367798 scopus 로고    scopus 로고
    • Widespread transcription at neuronal activity-regulated enhancers
    • Kim TK, Hemberg M, Gray JM, Costa AM, Bear DM, et al. 2010. Widespread transcription at neuronal activity-regulated enhancers. Nature 465:182-87
    • (2010) Nature , vol.465 , pp. 182-187
    • Kim, T.K.1    Hemberg, M.2    Gray, J.M.3    Costa, A.M.4    Bear, D.M.5
  • 38
    • 77952908743 scopus 로고    scopus 로고
    • A large fraction of extragenic RNA pol II transcription sites overlap enhancers
    • De Santa F, Barozzi I, Mietton F, Ghisletti S, Polletti S, et al. 2010. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol. 8:e1000384
    • (2010) PLoS Biol. , vol.8
    • De Santa, F.1    Barozzi, I.2    Mietton, F.3    Ghisletti, S.4    Polletti, S.5
  • 39
    • 79961022267 scopus 로고    scopus 로고
    • Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
    • Koch F, Fenouil R, Gut M, Cauchy P, Albert TK, et al. 2011. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat. Struct. Mol. Biol. 18:956-63
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 956-963
    • Koch, F.1    Fenouil, R.2    Gut, M.3    Cauchy, P.4    Albert, T.K.5
  • 40
    • 84870182699 scopus 로고    scopus 로고
    • Noncoding transcription at enhancers: General principles and functional models
    • Natoli G, Andrau JC. 2012. Noncoding transcription at enhancers: general principles and functional models. Annu. Rev. Genet. 46:1-19
    • (2012) Annu. Rev. Genet. , vol.46 , pp. 1-19
    • Natoli, G.1    Andrau, J.C.2
  • 41
    • 84879694221 scopus 로고    scopus 로고
    • Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
    • Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, et al. 2013. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature 498:511-15
    • (2013) Nature , vol.498 , pp. 511-515
    • Lam, M.T.1    Cho, H.2    Lesch, H.P.3    Gosselin, D.4    Heinz, S.5
  • 42
    • 0017102421 scopus 로고
    • Steroid receptors: Elements for modulation of eukaryotic transcription
    • Yamamoto KR, Alberts BM. 1976. Steroid receptors: elements for modulation of eukaryotic transcription. Annu. Rev. Biochem. 45:721-46
    • (1976) Annu. Rev. Biochem. , vol.45 , pp. 721-746
    • Yamamoto, K.R.1    Alberts, B.M.2
  • 43
    • 0025769412 scopus 로고
    • Primary response genes induced by growth factors and tumor promoters
    • Herschman HR. 1991. Primary response genes induced by growth factors and tumor promoters. Annu. Rev. Biochem. 60:281-319
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 281-319
    • Herschman, H.R.1
  • 44
    • 80555135917 scopus 로고    scopus 로고
    • Regulation of primary response genes
    • Fowler T, Ren R, Roy AL. 2011. Regulation of primary response genes. Mol. Cell 44:348-60
    • (2011) Mol. Cell , vol.44 , pp. 348-360
    • Fowler, T.1    Ren, R.2    Roy, A.L.3
  • 45
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
    • Sen R, Baltimore D. 1986. Inducibility of kappa immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell 47:921-28
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 46
    • 84856641109 scopus 로고    scopus 로고
    • NF-κB, the first quarter-century: Remarkable progress and outstanding questions
    • Hayden MS, Ghosh S. 2012. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 26:203-34
    • (2012) Genes Dev. , vol.26 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 47
    • 0030605518 scopus 로고    scopus 로고
    • Integration of growth factor signals at the c-fos serum response element
    • Price MA, Hill C, Treisman R. 1996. Integration of growth factor signals at the c-fos serum response element. Philos. Trans. R. Soc. B 351:551-59
    • (1996) Philos. Trans. R. Soc. B , vol.351 , pp. 551-559
    • Price, M.A.1    Hill, C.2    Treisman, R.3
  • 48
    • 33750343214 scopus 로고    scopus 로고
    • Actin' together: Serum response factor, its cofactors and the link to signal transduction
    • Posem G, Treisman R. 2006. Actin' together: serum response factor, its cofactors and the link to signal transduction. Trends Cell Biol. 16:588-96
    • (2006) Trends Cell Biol. , vol.16 , pp. 588-596
    • Posem, G.1    Treisman, R.2
  • 49
    • 0022799341 scopus 로고
    • Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast
    • Almer A, Horz W. 1986. Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast. EMBO J. 5:2681-87
    • (1986) EMBO J. , vol.5 , pp. 2681-2687
    • Almer, A.1    Horz, W.2
  • 50
    • 0022799080 scopus 로고
    • Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activation DNA elements
    • Almer A, Rudolph H, Hinnen A, Horz W. 1986. Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activation DNA elements. EMBO J. 5:2689-96
    • (1986) EMBO J. , vol.5 , pp. 2689-2696
    • Almer, A.1    Rudolph, H.2    Hinnen, A.3    Horz, W.4
  • 51
    • 0031655430 scopus 로고    scopus 로고
    • Requirements for chromatin modulation and transcription activation by the Pho4 acidic activation domain
    • McAndrew PC, Svaren J, Martin SR, Horz W, Goding CR. 1998. Requirements for chromatin modulation and transcription activation by the Pho4 acidic activation domain. Mol. Cell. Biol. 18:5818-27
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5818-5827
    • McAndrew, P.C.1    Svaren, J.2    Martin, S.R.3    Horz, W.4    Goding, C.R.5
  • 52
    • 0027258123 scopus 로고
    • Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation
    • Verdin E, Paras P, Van Lint C. 1993. Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J. 12:3249-59
    • (1993) EMBO J. , vol.12 , pp. 3249-3259
    • Verdin, E.1    Paras, P.2    Van Lint, C.3
  • 53
    • 1842314454 scopus 로고
    • Sequence-specific positioning of nucleosomes over the steroidinducible MMTV promoter
    • Richard-Foy H, Hager GL. 1987. Sequence-specific positioning of nucleosomes over the steroidinducible MMTV promoter. EMBO J. 6:2321-28
    • (1987) EMBO J. , vol.6 , pp. 2321-2328
    • Richard-Foy, H.1    Hager, G.L.2
  • 54
    • 0029115016 scopus 로고
    • Nucleosome positioning on the MMTV LTR result from the frequency-biased occupancy of multiple frames
    • Fragaso G, John S, Roberts MS, Hager GL. 1995. Nucleosome positioning on the MMTV LTR result from the frequency-biased occupancy of multiple frames. Genes Dev. 9:1933-47
    • (1995) Genes Dev. , vol.9 , pp. 1933-1947
    • Fragaso, G.1    John, S.2    Roberts, M.S.3    Hager, G.L.4
  • 55
    • 0023022087 scopus 로고
    • Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells
    • Siebenlist U, Durand DB, Bressler P, Holbrook NJ, Norris CA, et al. 1986. Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. Mol. Cell. Biol. 6:3042-49
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3042-3049
    • Siebenlist, U.1    Durand, D.B.2    Bressler, P.3    Holbrook, N.J.4    Norris, C.A.5
  • 56
    • 0032526641 scopus 로고    scopus 로고
    • Chromatin remodeling of the interleukin-2 gene: Distinct alterations in the proximal versus distal enhancer regions
    • Ward SB, Hernandez-Hoyas G, Chen F, Waterman M, Reeves R, Rothenberg EV. 1998. Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions. Nucleic Acids Res. 26:2923-34
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2923-2934
    • Ward, S.B.1    Hernandez-Hoyas, G.2    Chen, F.3    Waterman, M.4    Reeves, R.5    Rothenberg, E.V.6
  • 57
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal S, Rao A. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765-75
    • (1998) Immunity , vol.9 , pp. 765-775
    • Agarwal, S.1    Rao, A.2
  • 58
    • 0033451474 scopus 로고    scopus 로고
    • Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription
    • Weinmann AS, Plevy SE, Smale ST. 1999. Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity 11:665-75
    • (1999) Immunity , vol.11 , pp. 665-675
    • Weinmann, A.S.1    Plevy, S.E.2    Smale, S.T.3
  • 59
    • 0033681250 scopus 로고    scopus 로고
    • Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter
    • Agalioti T, Lomvardas S, Parekh B, Yie J,Maniatis T, Thanos D. 2000. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell 103:667-78
    • (2000) Cell , vol.103 , pp. 667-678
    • Agalioti, T.1    Lomvardas, S.2    Parekh, B.3    Yie Jmaniatis, T.4    Thanos, D.5
  • 60
    • 0032971444 scopus 로고    scopus 로고
    • Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-βpromoter
    • Parekh BS, Maniatis T. 1999. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-βpromoter. Mol. Cell 3:125-29
    • (1999) Mol. Cell , vol.3 , pp. 125-129
    • Parekh, B.S.1    Maniatis, T.2
  • 61
    • 0034026193 scopus 로고    scopus 로고
    • Promoter targeting and chromatin remodeling by the SWI/SNF complex
    • Peterson CL, Workman JL. 2000. Promoter targeting and chromatin remodeling by the SWI/SNF complex. Curr. Opin. Genet. Dev. 10:187-92
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 187-192
    • Peterson, C.L.1    Workman, J.L.2
  • 62
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li B, Carey M,Workman JL. 2007. The role of chromatin during transcription. Cell 128:707-19
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey Mworkman, J.L.2
  • 64
    • 77957253048 scopus 로고    scopus 로고
    • Control ofNF-κB-dependent transcriptional responses by chromatin organization
    • Natoli G. 2009. Control ofNF-κB-dependent transcriptional responses by chromatin organization. Cold Spring Harb. Perspect. Biol. 1:a000224
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1
    • Natoli, G.1
  • 66
    • 80051988785 scopus 로고    scopus 로고
    • Hierarchies of NF-κB target-gene regulation
    • Smale ST. 2011. Hierarchies of NF-κB target-gene regulation. Nat. Immunol. 12:689-94
    • (2011) Nat. Immunol. , vol.12 , pp. 689-694
    • Smale, S.T.1
  • 67
    • 0035908126 scopus 로고    scopus 로고
    • Two waves of nuclear factor κb recruitment to target promoters
    • Saccani S, Pantano S, Natoli G. 2001. Two waves of nuclear factor κB recruitment to target promoters. J. Exp. Med. 193:1351-59
    • (2001) J. Exp. Med. , vol.193 , pp. 1351-1359
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 68
    • 32044439558 scopus 로고    scopus 로고
    • Selective and antagonistic functions of SWI/SNF andMi-2βnucleosome remodeling complexes during an inflammatory response
    • Ramirez-Carrozzi VR,Nazarian AA, Li CC, Gore SL, Sridharan R, et al. 2006. Selective and antagonistic functions of SWI/SNF andMi-2βnucleosome remodeling complexes during an inflammatory response. Genes Dev. 20:282-96
    • (2006) Genes Dev. , vol.20 , pp. 282-296
    • Ramirez-Carrozzi, V.R.1    Nazarian, A.A.2    Li, C.C.3    Gore, S.L.4    Sridharan, R.5
  • 69
    • 67649669255 scopus 로고    scopus 로고
    • A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
    • Ramirez-Carrozzi VR, Braas D, Bhatt DM, Cheng CS, Hong C, et al. 2009. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138:114-28
    • (2009) Cell , vol.138 , pp. 114-128
    • Ramirez-Carrozzi, V.R.1    Braas, D.2    Bhatt, D.M.3    Cheng, C.S.4    Hong, C.5
  • 70
    • 10144228410 scopus 로고    scopus 로고
    • Purification and biochemical heterogeneity of the mammalian SWI-SNF complex
    • Wang W, Cote J, Xue J, Zhou S, Khavari PA, et al. 1996. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J. 15:5370-82
    • (1996) EMBO J. , vol.15 , pp. 5370-5382
    • Wang, W.1    Cote, J.2    Xue, J.3    Zhou, S.4    Khavari, P.A.5
  • 71
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • Hargreaves DC,Horng T, MedzhitovR. 2009. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138:129-45
    • (2009) Cell , vol.138 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 72
    • 84896913571 scopus 로고
    • DNA bending and its relation to nucleosome positioning
    • Drew HR, Travers AA. 1985. DNA bending and its relation to nucleosome positioning. J. Mol. Biol. 196:261-82
    • (1985) J. Mol. Biol. , vol.196 , pp. 261-282
    • Drew, H.R.1    Travers, A.A.2
  • 73
    • 0023001414 scopus 로고
    • Sequence periodicities in chicken nucleosome core DNA
    • Satchwell SC, Drew HR, Travers AA. 1986. Sequence periodicities in chicken nucleosome core DNA. J. Mol. Biol. 191:659-75
    • (1986) J. Mol. Biol. , vol.191 , pp. 659-675
    • Satchwell, S.C.1    Drew, H.R.2    Travers, A.A.3
  • 74
    • 0032512794 scopus 로고    scopus 로고
    • New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning
    • Lowary PT, Widom J. 1998. New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning. J. Mol. Biol. 276:19-42
    • (1998) J. Mol. Biol. , vol.276 , pp. 19-42
    • Lowary, P.T.1    Widom, J.2
  • 75
    • 84870485829 scopus 로고    scopus 로고
    • CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
    • Fenouil R, Cauchy P, Koch F, Descostes N, Cabeza JZ, et al. 2012. CpG islands and GC content dictate nucleosome depletion in a transcription- independent manner at mammalian promoters. Genome Res. 22:2399-408
    • (2012) Genome Res. , vol.22 , pp. 2399-2408
    • Fenouil, R.1    Cauchy, P.2    Koch, F.3    Descostes, N.4    Cabeza, J.Z.5
  • 76
    • 84884693205 scopus 로고    scopus 로고
    • Binding of NF-κB to nucleosomes: Effect of translational positioning, nucleosome remodeling, and linker histone H1
    • Lone IN, ShuklaMS, Charles Richard JL, Peshev ZY, Dimitrov S, Angelov D. 2013. Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling, and linker histone H1. PLoS Genet. 9:e1003830
    • (2013) PLoS Genet. , vol.9
    • Lone, I.N.1    Shukla, M.S.2    Charles Richard, J.L.3    Peshev, Z.Y.4    Dimitrov, S.5    Angelov, D.6
  • 77
    • 0035221154 scopus 로고    scopus 로고
    • Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event
    • Weinmann AS,MitchellDM, Sanjabi S, BradleyMN, Hoffmann A, et al. 2001. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat. Immunol. 2:51-57
    • (2001) Nat. Immunol. , vol.2 , pp. 51-57
    • Weinmann, A.S.1    Mitchell, D.M.2    Sanjabi, S.3    Bradley, M.N.4    Hoffmann, A.5
  • 78
    • 77953980528 scopus 로고    scopus 로고
    • IL-6: From its discovery to clinical applications
    • Kishimoto T. 2010. IL-6: from its discovery to clinical applications. Int. Immunol. 22:347-52
    • (2010) Int. Immunol. , vol.22 , pp. 347-352
    • Kishimoto, T.1
  • 79
    • 77954096689 scopus 로고    scopus 로고
    • IL-6: Regulator of Treg/Th17 balance
    • Kimura A, Kishimoto T. 2010. IL-6: regulator of Treg/Th17 balance. Eur. J. Immunol. 40:1830-35
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1830-1835
    • Kimura, A.1    Kishimoto, T.2
  • 80
    • 84864251757 scopus 로고    scopus 로고
    • Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions
    • Bhatt DM, Pandya-Jones A, Tong AJ, Barozzi I, Lissner MM, et al. 2012. Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell 150:279-90
    • (2012) Cell , vol.150 , pp. 279-290
    • Bhatt, D.M.1    Pandya-Jones, A.2    Tong, A.J.3    Barozzi, I.4    Lissner, M.M.5
  • 81
    • 70350754328 scopus 로고    scopus 로고
    • Jmjd3 contributes to the control of gene expression in LPS-Activated macrophages
    • De Santa F, Narang V, Yap ZH, Tusi BK, Burgold T, et al. 2009. Jmjd3 contributes to the control of gene expression in LPS-Activated macrophages. EMBO J. 28:3341-52
    • (2009) EMBO J. , vol.28 , pp. 3341-3352
    • De Santa, F.1    Narang, V.2    Zh, Y.3    Tusi, B.K.4    Burgold, T.5
  • 82
    • 84876871047 scopus 로고    scopus 로고
    • Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put
    • Simon JA, Kingston RE. 2013. Occupying chromatin: polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol. Cell 49:808-24
    • (2013) Mol. Cell , vol.49 , pp. 808-824
    • Simon, J.A.1    Kingston, R.E.2
  • 83
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor κb pathway
    • Perkins ND. 2006. Post-translational modifications regulating the activity and function of the nuclear factor κB pathway. Oncogene 25:6717-30
    • (2006) Oncogene , vol.25 , pp. 6717-6730
    • Perkins, N.D.1
  • 84
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the co-Activator CBP/p300
    • Zhong H, Voll RE, Ghosh S. 1998. Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the co-Activator CBP/p300. Mol. Cell 1:661-71
    • (1998) Mol. Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 85
    • 0035979737 scopus 로고    scopus 로고
    • Duration of nuclear NF-κB action regulated by reversible acetylation
    • Chen LF, Fischle W, Verdin E, Greene WC. 2001. Duration of nuclear NF-κB action regulated by reversible acetylation. Science 293:1653-57
    • (2001) Science , vol.293 , pp. 1653-1657
    • Chen, L.F.1    Fischle, W.2    Verdin, E.3    Greene, W.C.4
  • 86
    • 0036203419 scopus 로고    scopus 로고
    • Phosphorylation of nuclear NF-κB governs its association with either HDAC-1 or CBP/p300: A mechanism for regulating the transcriptional activity of NF-κB
    • Zhong H, May MJ, Jimi E, Ghosh S. 2002. Phosphorylation of nuclear NF-κB governs its association with either HDAC-1 or CBP/p300: a mechanism for regulating the transcriptional activity of NF-κB. Mol. Cell 9:625-36
    • (2002) Mol. Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 87
    • 0042525909 scopus 로고    scopus 로고
    • Essential role of RelA Ser311 phosphorylation by ?PKC in NF-κB transcriptional activation
    • Duran A, Diaz-Meco MT, Moscat J. 2003. Essential role of RelA Ser311 phosphorylation by ?PKC in NF-κB transcriptional activation. EMBO J. 22:3910-18
    • (2003) EMBO J. , vol.22 , pp. 3910-3918
    • Duran, A.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 88
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, et al. 2004. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23:2369-80
    • (2004) EMBO J. , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5
  • 89
    • 43249114058 scopus 로고    scopus 로고
    • Epigenetic regulation ofNF-κB dependent gene expression
    • Dong J, Jimi E, ZhongH,HaydenMS, Ghosh S. 2008. Epigenetic regulation ofNF-κB dependent gene expression. Genes Dev. 22:1159-73
    • (2008) Genes Dev. , vol.22 , pp. 1159-1173
    • Dong, J.1    Jimi, E.2    Zhong, H.3    Hayden, M.S.4    Ghosh, S.5
  • 90
    • 73149099403 scopus 로고    scopus 로고
    • Regulation of NF-κB activity through lysine monomethylation of p65
    • Ea CK, Baltimore D. 2009. Regulation of NF-κB activity through lysine monomethylation of p65. Proc. Natl. Acad. Sci. USA 106:18972-77
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 18972-18977
    • Ea, C.K.1    Baltimore, D.2
  • 91
    • 67349285384 scopus 로고    scopus 로고
    • Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit
    • Yang XD, Yuang B, Li M, Lamb A, Kelleher NL, Chen LF. 2009. Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J. 28:1055-66
    • (2009) EMBO J. , vol.28 , pp. 1055-1066
    • Yang, X.D.1    Yuang, B.2    Li, M.3    Lamb, A.4    Kelleher, N.L.5    Chen, L.F.6
  • 92
    • 61749088806 scopus 로고    scopus 로고
    • Brd4 coactivates transcriptional activation of NF-κB via specific binding to acetylated RelA
    • Huang B, Yang XD, Zhou MM, Ozato K, Chen LF. 2009. Brd4 coactivates transcriptional activation of NF-κB via specific binding to acetylated RelA. Mol. Cell. Biol. 29:1375-87
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1375-1387
    • Huang, B.1    Yang, X.D.2    Zhou, M.M.3    Ozato, K.4    Chen, L.F.5
  • 93
    • 77950642805 scopus 로고    scopus 로고
    • Functional interplay between acetylation and methylation of the RelA subunit of NF-κB
    • Yang XD, Tajkhorshid E, Chen LF. 2010. Functional interplay between acetylation and methylation of the RelA subunit of NF-κB. Mol. Cell. Biol. 30:2170-80
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 2170-2180
    • Yang, X.D.1    Tajkhorshid, E.2    Chen, L.F.3
  • 94
    • 78650308842 scopus 로고    scopus 로고
    • Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
    • Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, et al. 2011. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat. Immunol. 12:29-36
    • (2011) Nat. Immunol. , vol.12 , pp. 29-36
    • Levy, D.1    Kuo, A.J.2    Chang, Y.3    Schaefer, U.4    Kitson, C.5
  • 95
    • 84867650919 scopus 로고    scopus 로고
    • Modification of RelA by O-linked N-Acetylglucosamine links glucose metabolism toNF-κB acetylation and transcription
    • Allison DF, Wamsley JJ, Kumar M, Li D, Gray LG, et al. 2012. Modification of RelA by O-linked N-Acetylglucosamine links glucose metabolism toNF-κB acetylation and transcription. Proc. Natl. Acad. Sci. USA 109:16888-93
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 16888-16893
    • Allison, D.F.1    Wamsley, J.J.2    Kumar, M.3    Li, D.4    Gray, L.G.5
  • 96
    • 84857794577 scopus 로고    scopus 로고
    • Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1
    • Liu Y,MayoMW, Nagji AS, Smith PW, RamseyCS, et al. 2012. Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1. Oncogene 31:1143-54
    • (2012) Oncogene , vol.31 , pp. 1143-1154
    • Ymayomw, L.1    Nagji, A.S.2    Simth, P.W.3    Ramsey, C.S.4
  • 97
    • 84882370181 scopus 로고    scopus 로고
    • Role of lysine methylation of NF-κB in differential gene regulation
    • Lu T, Yang M, Huang DB, Wei H, Ozer GH, et al. 2013. Role of lysine methylation of NF-κB in differential gene regulation. Proc. Natl. Acad. Sci. USA 110:13510-15
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 13510-13515
    • Lu, T.1    Yang, M.2    Huang, D.B.3    Wei, H.4    Ozer, G.H.5
  • 100
    • 19944431570 scopus 로고    scopus 로고
    • Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-κB-dependent gene expression
    • Covic M, Hassa PO, Saccani S, Buerki C, Meier NI, et al. 2005. Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-κB- dependent gene expression. EMBO J. 24:85-96
    • (2005) EMBO J. , vol.24 , pp. 85-96
    • Covic, M.1    Hassa, P.O.2    Saccani, S.3    Buerki, C.4    Meier, N.I.5
  • 101
    • 40649124718 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 1 coactivates NF-κB-dependent gene expression synergistically with CARM1 and PARP1
    • Hassa PO, Covic M, BedfordMT, HottigerMO. 2008. Protein arginine methyltransferase 1 coactivates NF-κB-dependent gene expression synergistically with CARM1 and PARP1. J. Mol. Biol. 377:668-78
    • (2008) J. Mol. Biol. , vol.377 , pp. 668-678
    • Hassa, P.O.1    Covic, M.2    Bedford, M.T.3    Hottiger, M.O.4
  • 102
    • 36248944103 scopus 로고    scopus 로고
    • Ribosomal protein S3: A KH domain subunit in NF-κB complexes that mediates selective gene regulation
    • Wan F, Anderson DE, Barnitz RA, Snow A, Bidere N, et al. 2007. Ribosomal protein S3: a KH domain subunit in NF-κB complexes that mediates selective gene regulation. Cell 131:927-39
    • (2007) Cell , vol.131 , pp. 927-939
    • Wan, F.1    Anderson, D.E.2    Barnitz, R.A.3    Snow, A.4    Bidere, N.5
  • 103
    • 50049112829 scopus 로고    scopus 로고
    • Role of nuclear IκB proteins in the regulation of host immune responses
    • Yamamoto M, Takeda K. 2008. Role of nuclear IκB proteins in the regulation of host immune responses. J. Infect. Chemother. 14:265-69
    • (2008) J. Infect. Chemother. , vol.14 , pp. 265-269
    • Yamamoto, M.1    Takeda, K.2
  • 104
    • 66149122282 scopus 로고    scopus 로고
    • Two modes of transcriptional activation at native promoters by NF-κB p65
    • van Essen D, Engist B, Natoli G, Saccani S. 2009. Two modes of transcriptional activation at native promoters by NF-κB p65. PLoS Biol. 7:e73
    • (2009) PLoS Biol. , vol.7
    • Van Essen, D.1    Engist, B.2    Natoli, G.3    Saccani, S.4
  • 106
    • 84884586171 scopus 로고    scopus 로고
    • Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription
    • Mukherjee SP, Behar M, Birnbaum HA, Hoffmann A, Wright PE, Ghosh G. 2013. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS Biol. 11:e1001647
    • (2013) PLoS Biol. , vol.11
    • Mukherjee, S.P.1    Behar, M.2    Birnbaum, H.A.3    Hoffmann, A.4    Wright, P.E.5    Ghosh, G.6
  • 108
    • 84857767452 scopus 로고    scopus 로고
    • The epigenetic landscape of lineage choice: Lessons from the heritability of CD4 and CD8 expression
    • Gialitakis M, Sellars M, Littman DR. 2012. The epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expression. Curr. Top. Microbiol. Immunol. 356:165-88
    • (2012) Curr. Top. Microbiol. Immunol. , vol.356 , pp. 165-188
    • Gialitakis, M.1    Sellars, M.2    Littman, D.R.3
  • 109
    • 84876888289 scopus 로고    scopus 로고
    • Epigenetics: Core misconcept
    • Ptashne M. 2013. Epigenetics: core misconcept. Proc. Natl. Acad. Sci. USA 110:7101-13
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 7101-7113
    • Ptashne, M.1
  • 110
    • 80052159733 scopus 로고    scopus 로고
    • Inflammatory signaling in macrophages: Transitions from acute to tolerant and alternative activation states
    • Ivashkiv LB. 2011. Inflammatory signaling in macrophages: transitions from acute to tolerant and alternative activation states. Eur. J. Immunol. 41:2477-81
    • (2011) Eur. J. Immunol. , vol.41 , pp. 2477-2481
    • Ivashkiv, L.B.1
  • 111
    • 84877119701 scopus 로고    scopus 로고
    • Epigenetic regulation of macrophage polarization and function
    • Ivashkiv LB. 2013. Epigenetic regulation of macrophage polarization and function. Trends Immunol. 34:216-23
    • (2013) Trends Immunol. , vol.34 , pp. 216-223
    • Ivashkiv, L.B.1
  • 112
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster SL,Hargreaves DC,Medzhitov R. 2007. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447:972-78
    • (2007) Nature , vol.447 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 113
    • 84865547244 scopus 로고    scopus 로고
    • Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome
    • Yan Q, Carmody RJ, Qu Z, Ruan Q, Jager J, et al. 2012. Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome. Proc. Natl. Acad. Sci. USA 109:14140-45
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 14140-14145
    • Yan, Q.1    Carmody, R.J.2    Qu, Z.3    Ruan, Q.4    Jager, J.5
  • 114
    • 84870199424 scopus 로고    scopus 로고
    • NF-κB as a target for modulating inflammatory responses
    • Gasparini C, Feldmann M. 2012. NF-κB as a target for modulating inflammatory responses. Curr. Pharm. Des. 18:5735-45
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 5735-5745
    • Gasparini, C.1    Feldmann, M.2
  • 115
    • 0037138363 scopus 로고    scopus 로고
    • Bromodomain: An acetyl-lysine binding domain
    • Zeng L, Zhou MM. 2002. Bromodomain: an acetyl-lysine binding domain. FEBS Lett. 513:124-28
    • (2002) FEBS Lett. , vol.513 , pp. 124-128
    • Zeng, L.1    Zhou, M.M.2
  • 116
    • 34547858913 scopus 로고    scopus 로고
    • Structure and acetyl-lysine recognition of the bromodomain
    • Mujtaba S, Zeng L, Zhou MM. 2007. Structure and acetyl-lysine recognition of the bromodomain. Oncogene 26:5521-27
    • (2007) Oncogene , vol.26 , pp. 5521-5527
    • Mujtaba, S.1    Zeng, L.2    Zhou, M.M.3
  • 117
    • 70149112313 scopus 로고    scopus 로고
    • Histone crosstalk between H3S10ph and K4K16ac generates a histone code that mediates transcription elongation
    • Zippo A, Serafini R, Rocchigiani M, Pennacchini S, Krepelova A, Oliviero S. 2009. Histone crosstalk between H3S10ph and K4K16ac generates a histone code that mediates transcription elongation. Cell 138:1122-36
    • (2009) Cell , vol.138 , pp. 1122-1136
    • Zippo, A.1    Serafini, R.2    Rocchigiani, M.3    Pennacchini, S.4    Krepelova, A.5    Oliviero, S.6
  • 118
    • 84864578590 scopus 로고    scopus 로고
    • The bromodomain interaction module
    • Filippakopoulos P, Knapp S. 2012. The bromodomain interaction module. FEBS Lett. 586:2692-704
    • (2012) FEBS Lett. , vol.586 , pp. 2692-2704
    • Filippakopoulos, P.1    Knapp, S.2
  • 119
    • 84859181036 scopus 로고    scopus 로고
    • Histone recognition and large-scale structural analysis of the human bromodomain family
    • Filippakopoulos P, Picaud S, Mangos M, Keates T, Lambert JP, et al. 2012. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell 149:214-31
    • (2012) Cell , vol.149 , pp. 214-231
    • Filippakopoulos, P.1    Picaud, S.2    Mangos, M.3    Keates, T.4    Lambert, J.P.5
  • 120
    • 0041806599 scopus 로고    scopus 로고
    • The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
    • Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. 2003. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. USA 100:8758-63
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8758-8763
    • Dey, A.1    Chitsaz, F.2    Abbasi, A.3    Misteli, T.4    Ozato, K.5
  • 122
    • 79959483607 scopus 로고    scopus 로고
    • The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3
    • Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, et al. 2011. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Mol. Cell. Biol. 31:2641-52
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 2641-2652
    • Rahman, S.1    Sowa, M.E.2    Ottinger, M.3    Smith, J.A.4    Shi, Y.5
  • 123
    • 84862911038 scopus 로고    scopus 로고
    • Two-pronged binding with bromodomaincontaining protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes
    • Schr oder S,Cho S, Zeng L, ZhangQ,KaehlckeK, et al. 2012. Two-pronged binding with bromodomaincontaining protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. J. Biol. Chem. 287:1090-99
    • (2012) J. Biol. Chem. , vol.287 , pp. 1090-1099
    • Schroder, S.1    Cho, S.2    Zeng, L.3    Zhang, Q.4    Kaehlcke, K.5
  • 124
    • 33746403681 scopus 로고    scopus 로고
    • Controlling the elongation phase of transcription with P-TEFb
    • Peterlin BM, Price DH. 2006. Controlling the elongation phase of transcription with P-TEFb. Mol. Cell 23:297-305
    • (2006) Mol. Cell , vol.23 , pp. 297-305
    • Peterlin, B.M.1    Price, D.H.2
  • 125
    • 84861857476 scopus 로고    scopus 로고
    • RNA polymerase II elongation control
    • Zhou Q, Li T, Price DH. 2012. RNA polymerase II elongation control. Annu. Rev. Biochem. 81:119-43
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 119-143
    • Zhou, Q.1    Li, T.2    Price, D.H.3
  • 126
    • 80054984945 scopus 로고    scopus 로고
    • Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
    • Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, et al. 2011. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 478:529-33
    • (2011) Nature , vol.478 , pp. 529-533
    • Dawson, M.A.1    Prinjha, R.K.2    Dittmann, A.3    Giotopoulos, G.4    Bantscheff, M.5
  • 127
    • 84862738480 scopus 로고    scopus 로고
    • BET domain co-regulators in obesity, inflammation and cancer
    • Belkina AC, Denis GV. 2012. BET domain co-regulators in obesity, inflammation and cancer. Nat. Rev. Cancer 12:465-77
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 465-477
    • Belkina, A.C.1    Denis, G.V.2
  • 128
    • 0028981016 scopus 로고
    • Evolution and developmental regulation of the major histocompatibility complex
    • Salter-Cid L, FlajnikMF. 1995. Evolution and developmental regulation of the major histocompatibility complex. Crit. Rev. Immunol. 15:31-75
    • (1995) Crit. Rev. Immunol. , vol.15 , pp. 31-75
    • Salter-Cid, L.1    Flajnik, M.F.2
  • 129
    • 84873256270 scopus 로고    scopus 로고
    • BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
    • Belkina AC, Nikolajczyk BS, Denis GV. 2013. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. J. Immunol. 190:3670-78
    • (2013) J. Immunol. , vol.190 , pp. 3670-3678
    • Belkina, A.C.1    Nikolajczyk, B.S.2    Denis, G.V.3
  • 130
    • 35848961668 scopus 로고    scopus 로고
    • How chromatin-binding modules interpret histone modifications: Lessons from professional pocket pickers
    • Taverna SD, LiH, Ruthenburg AJ, Allis CD, Patel DJ. 2007. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat. Struct. Mol. Biol. 14:1025-40
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 1025-1040
    • Taverna, S.D.1    Li, H.2    Ruthenburg, A.J.3    Allis, C.D.4    Patel, D.J.5
  • 132
  • 133
    • 84859908391 scopus 로고    scopus 로고
    • When bacteria target the nucleus: The emerging family of nucleomodulins
    • Bierne H, Cossart P. 2012. When bacteria target the nucleus: the emerging family of nucleomodulins. Cell. Microbiol. 14:622-33
    • (2012) Cell. Microbiol. , vol.14 , pp. 622-633
    • Bierne, H.1    Cossart, P.2
  • 135
    • 84862271027 scopus 로고    scopus 로고
    • Adenovirus evasion of interferon-mediated innate immunity by direct antagonism of a cellular histone posttranslational modification
    • Fonseca GJ, Thillainadesan G, Yousef AF, Ablack JN, Mossman KL, et al. 2012. Adenovirus evasion of interferon-mediated innate immunity by direct antagonism of a cellular histone posttranslational modification. Cell Host Microbe 11:597-606
    • (2012) Cell Host Microbe , vol.11 , pp. 597-606
    • Fonseca, G.J.1    Thillainadesan, G.2    Yousef, A.F.3    Ablack, J.N.4    Mossman, K.L.5
  • 136
    • 0036123253 scopus 로고    scopus 로고
    • Ctr9, Rtf1, and Leo1 are components of the PAF1/RNA polymerase II complex
    • Mueller CL, Jaehning JA. 2002. Ctr9, Rtf1, and Leo1 are components of the PAF1/RNA polymerase II complex. Mol. Cell. Biol. 22:1971-80
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1971-1980
    • Mueller, C.L.1    Jaehning, J.A.2
  • 137
    • 77953277032 scopus 로고    scopus 로고
    • The Paf1 complex: Platform or player in RNA polymerase II transcription?
    • Jaehning JA. 2010. The Paf1 complex: platform or player in RNA polymerase II transcription? Biochim. Biophys. Acta 1799:379-88
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 379-388
    • Jaehning, J.A.1
  • 138
    • 68949149115 scopus 로고    scopus 로고
    • Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1- Rad6 interactions mediate histone H2B ubiquitylation in yeast
    • Kim J, Roeder RG. 2009. Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1- Rad6 interactions mediate histone H2B ubiquitylation in yeast. J. Biol. Chem. 284:20582-92
    • (2009) J. Biol. Chem. , vol.284 , pp. 20582-20592
    • Kim, J.1    Roeder, R.G.2
  • 139
    • 65249105512 scopus 로고    scopus 로고
    • RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
    • Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, et al. 2009. RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137:459-71
    • (2009) Cell , vol.137 , pp. 459-471
    • Kim, J.1    Guermah, M.2    McGinty, R.K.3    Lee, J.S.4    Tang, Z.5
  • 140
    • 36849046285 scopus 로고    scopus 로고
    • Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS
    • Lee JS, Shukla A, Schneider J, Swanson SK, WashburnMP, et al. 2007. Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 131:1084-96
    • (2007) Cell , vol.131 , pp. 1084-1096
    • Lee, J.S.1    Shukla, A.2    Schneider, J.3    Swanson, S.K.4    Washburn, M.P.5
  • 141
  • 142
    • 84865419994 scopus 로고    scopus 로고
    • The super elongation complex (SEC) family in transcriptional control
    • Luo Z, LinC, Shilatifard A. 2012. The super elongation complex (SEC) family in transcriptional control. Nat. Rev. Mol. Cell Biol. 13:543-47
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 543-547
    • Luo, Z.1    Linc Shilatifard, A.2
  • 143
    • 67449097020 scopus 로고    scopus 로고
    • The NS1 protein of a human influenza virus inhibits type 1 interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells
    • Haye K, Burmakina S, Moran T, Garcia-Sastre A, Fernandez-Sesma A. 2009. The NS1 protein of a human influenza virus inhibits type 1 interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells. J. Virol. 83:6849-62
    • (2009) J. Virol. , vol.83 , pp. 6849-6862
    • Haye, K.1    Burmakina, S.2    Moran, T.3    Garcia-Sastre, A.4    Fernandez-Sesma, A.5
  • 144
  • 145
    • 34250810666 scopus 로고    scopus 로고
    • Multiple anti-interferon actions of the influenza A virus NS1 protein
    • Kochs G, Garcia-Sastre A, Martinez-Sobrido L. 2007. Multiple anti-interferon actions of the influenza A virus NS1 protein. J. Virol. 81:7011-21
    • (2007) J. Virol. , vol.81 , pp. 7011-7021
    • Kochs, G.1    Garcia-Sastre, A.2    Martinez-Sobrido, L.3
  • 146
    • 84862777909 scopus 로고    scopus 로고
    • Suppression of the antiviral response by an influenza histone mimic
    • Marazzi I, Ho JS, Kim J, Manicassamy B, Dewell S, et al. 2012. Suppression of the antiviral response by an influenza histone mimic. Nature 483:428-33
    • (2012) Nature , vol.483 , pp. 428-433
    • Marazzi, I.1    Ho, J.S.2    Kim, J.3    Manicassamy, B.4    Dewell, S.5


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