Epigenetic regulation of tumor necrosis factor α (TNFα) release in human macrophages by HIV-1 single-stranded RNA (ssRNA) is dependent on TLR8 signaling

Journal of Biological Chemistry

Volumn 287, Issue 17, 2012, Pages 13778-13786

  Han, Xinbing ^a   Li, Xin ^a   Yue, Simon C ^a   Anandaiah, Asha ^a   Hashem, Falah ^a   Reinach, Peter S ^b   Koziel, Henry ^a   Tachado, Souvenir D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALVEOLAR MACROPHAGES; CHROMATIN REMODELING; CORECEPTORS; DOSE-DEPENDENT MANNER; EPIGENETIC REGULATION; GENE KNOCK DOWN; HIV INFECTION; HUMAN MACROPHAGES; INNATE IMMUNE RESPONSE; REVERSE TRANSCRIPTION; SIGNALING PATHWAYS; TOLL-LIKE RECEPTORS; TRIMETHYLATION; TUMOR NECROSIS FACTORS; VIRAL REPLICATION;

ACETYLATION; ACIDIFICATION; AMINO ACIDS; ENZYME ACTIVITY; GENES; MACROPHAGES; MOLECULAR BIOLOGY; RNA; TRANSCRIPTION; VIRUSES;

DISEASES;

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; HISTONE H3; HISTONE H4; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

ACIDIFICATION; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; EPIGENETICS; GENE SILENCING; GENETIC REGULATION; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOMODULATION; INNATE IMMUNITY; MACROPHAGE FUNCTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; EPIGENESIS, GENETIC; HIV INFECTIONS; HIV-1; HUMANS; MACROPHAGES; MACROPHAGES, ALVEOLAR; OLIGONUCLEOTIDES; RNA; RNA, VIRAL; TOLL-LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859958476     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.342683     Document Type: Article

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