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Volumn 33, Issue 5, 2016, Pages 1055-1073

Microneedles: A New Frontier in Nanomedicine Delivery

Author keywords

drug delivery; microneedles; microparticles; nanomedicine; nanoparticles; vaccines

Indexed keywords

METAL NANOPARTICLE; MINERAL; NANOCARRIER; NANOPARTICLE; NANOSTRUCTURED LIPID CARRIER; OVALBUMIN; POLYMER; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG; VACCINE; DRUG; DRUG CARRIER;

EID: 84959104625     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-016-1885-5     Document Type: Review
Times cited : (255)

References (153)
  • 1
    • 33749820952 scopus 로고    scopus 로고
    • The emerging nanomedicine landscape
    • 1:CAS:528:DC%2BD28XhtVGgsrvI 17033654
    • Wagner V, Dullaart A, Bock AK, Zweck A. The emerging nanomedicine landscape. Nat Biotechnol. 2006;24(10):1211-7.
    • (2006) Nat Biotechnol , vol.24 , Issue.10 , pp. 1211-1217
    • Wagner, V.1    Dullaart, A.2    Bock, A.K.3    Zweck, A.4
  • 2
    • 14644396096 scopus 로고    scopus 로고
    • Nanomedicine: Current status and future prospects
    • 1:CAS:528:DC%2BD2MXit1ygsLw%3D 15746175
    • Moghimi SM, Hunter AC, Murray JC. Nanomedicine: current status and future prospects. FASEB J. 2005;19(3):311-30.
    • (2005) FASEB J , vol.19 , Issue.3 , pp. 311-330
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 3
    • 84855824016 scopus 로고    scopus 로고
    • Nanoparticles: A boon to drug delivery, therapeutics, diagnostics and imaging
    • 1:CAS:528:DC%2BC38Xos12htQ%3D%3D 21703993
    • Parveen S, Misra R, Sahoo SK. Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging. Nanomedicine. 2012;8(2):147-66.
    • (2012) Nanomedicine , vol.8 , Issue.2 , pp. 147-166
    • Parveen, S.1    Misra, R.2    Sahoo, S.K.3
  • 4
    • 79953198946 scopus 로고    scopus 로고
    • Nanoparticles and microparticles for skin drug delivery
    • 1:CAS:528:DC%2BC3MXntVyrur4%3D 21315122
    • Prow TW, Grice JE, Lin LL, Faye R, Butler M, Becker W, et al. Nanoparticles and microparticles for skin drug delivery. Adv Drug Deliv Rev. 2011;63(6):470-91.
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.6 , pp. 470-491
    • Prow, T.W.1    Grice, J.E.2    Lin, L.L.3    Faye, R.4    Butler, M.5    Becker, W.6
  • 8
    • 55749108348 scopus 로고    scopus 로고
    • Transdermal drug delivery
    • 1:CAS:528:DC%2BD1cXhtlCktrrF 18997767 2700785
    • Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol. 2008;26(11):1261-8.
    • (2008) Nat Biotechnol , vol.26 , Issue.11 , pp. 1261-1268
    • Prausnitz, M.R.1    Langer, R.2
  • 10
    • 0032403467 scopus 로고    scopus 로고
    • Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract
    • 1:CAS:528:DyaK1cXnsFWlt78%3D 10837678
    • Ponchel G, Irache JM. Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv Drug Deliv Rev. 1998;34(2-3):191-219.
    • (1998) Adv Drug Deliv Rev , vol.34 , Issue.2-3 , pp. 191-219
    • Ponchel, G.1    Irache, J.M.2
  • 12
    • 0032722481 scopus 로고    scopus 로고
    • The cost of unsafe injections
    • 1:STN:280:DC%2BD3c%2FmtVKisQ%3D%3D 10593028 2557745
    • Miller MA, Pisani E. The cost of unsafe injections. Bull World Health Organ. 1999;77(10):808-11.
    • (1999) Bull World Health Organ , vol.77 , Issue.10 , pp. 808-811
    • Miller, M.A.1    Pisani, E.2
  • 13
    • 6244275503 scopus 로고
    • On dichloroethylsulphide (mustard gas). IV, the mechanism of absorption by the skin
    • 1:CAS:528:DyaB3cXhsFWj
    • Smith HW, Clowes GHA, Marshall EK. On dichloroethylsulphide (mustard gas). IV, the mechanism of absorption by the skin. J Pharm Exp Ther. 1919;13(1):1-30.
    • (1919) J Pharm Exp Ther , vol.13 , Issue.1 , pp. 1-30
    • Smith, H.W.1    Clowes, G.H.A.2    Marshall, E.K.3
  • 14
    • 0014041531 scopus 로고
    • Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration
    • 1:STN:280:DyaF2s%2FptFyitQ%3D%3D 6018244
    • Scheuplein RJ. Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration. J Invest Dermatol. 1967;48(1):79-88.
    • (1967) J Invest Dermatol , vol.48 , Issue.1 , pp. 79-88
    • Scheuplein, R.J.1
  • 17
    • 1242308254 scopus 로고    scopus 로고
    • Current status and future potential of transdermal drug delivery
    • 1:CAS:528:DC%2BD2cXhtlartbg%3D 15040576
    • Prausnitz MR, Mitragotri S, Langer R. Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov. 2004;3(2):115-24.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.2 , pp. 115-124
    • Prausnitz, M.R.1    Mitragotri, S.2    Langer, R.3
  • 20
    • 73949137818 scopus 로고    scopus 로고
    • Penetration of nanoparticles and nanomaterials in the skin: Fiction or reality?
    • 1:CAS:528:DC%2BD1MXhsVylsrfL 19670463
    • Baroli B. Penetration of nanoparticles and nanomaterials in the skin: fiction or reality? J Pharm Sci. 2010;99(1):21-50.
    • (2010) J Pharm Sci , vol.99 , Issue.1 , pp. 21-50
    • Baroli, B.1
  • 22
    • 1542358759 scopus 로고    scopus 로고
    • Microneedles for transdermal drug delivery
    • 1:CAS:528:DC%2BD2cXhvFWqsbw%3D 15019747
    • Prausnitz MR. Microneedles for transdermal drug delivery. Adv Drug Deliv Rev. 2004;56(5):581-7.
    • (2004) Adv Drug Deliv Rev , vol.56 , Issue.5 , pp. 581-587
    • Prausnitz, M.R.1
  • 25
    • 84908114882 scopus 로고    scopus 로고
    • Children's views on microneedle use as an alternative to blood sampling for patient monitoring
    • 24308565
    • Mooney K, McElnay JC, Donnelly RF. Children's views on microneedle use as an alternative to blood sampling for patient monitoring. Int J Pharm Pract. 2014;22(5):335-44.
    • (2014) Int J Pharm Pract , vol.22 , Issue.5 , pp. 335-344
    • Mooney, K.1    McElnay, J.C.2    Donnelly, R.F.3
  • 27
    • 84873523117 scopus 로고    scopus 로고
    • Modeling the human skin barrier - Towards a better understanding of dermal absorption
    • 1:CAS:528:DC%2BC38XmvFKgsLw%3D 22525516
    • Jepps OG, Dancik Y, Anissimov YG, Roberts MS. Modeling the human skin barrier - Towards a better understanding of dermal absorption. Adv Drug Deliv Rev. 2013;65(2):152-68.
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.2 , pp. 152-168
    • Jepps, O.G.1    Dancik, Y.2    Anissimov, Y.G.3    Roberts, M.S.4
  • 29
    • 0024797821 scopus 로고
    • The barrier function of the skin in relation to percutaneous absorption of drugs
    • 1:CAS:528:DyaK3cXhtVClsLg%3D
    • Wiechers JW. The barrier function of the skin in relation to percutaneous absorption of drugs. Pharm Weekblad Sci. 1989;11(6):185-98.
    • (1989) Pharm Weekblad Sci , vol.11 , Issue.6 , pp. 185-198
    • Wiechers, J.W.1
  • 30
    • 0016545625 scopus 로고
    • Drug permeation through human skin: Theory andinvitro experimental measurement
    • 1:CAS:528:DyaE2MXlvVyitbg%3D
    • Michaels AS, Chandrasekaran SK, Shaw JE. Drug permeation through human skin: theory andinvitro experimental measurement. AICHE J. 1975;21(5):985-96.
    • (1975) AICHE J , vol.21 , Issue.5 , pp. 985-996
    • Michaels, A.S.1    Chandrasekaran, S.K.2    Shaw, J.E.3
  • 31
    • 0025955486 scopus 로고
    • Structural investigations of human stratum corneum by small-angle X-Ray scattering
    • 1:STN:280:DyaK38%2FosV2msg%3D%3D 1748810
    • Bouwstra JA, Gooris GS, van der Spek JA, Bras W. Structural investigations of human stratum corneum by small-angle X-Ray scattering. J Invest Dermatol. 1991;97(6):1005-12.
    • (1991) J Invest Dermatol , vol.97 , Issue.6 , pp. 1005-1012
    • Bouwstra, J.A.1    Gooris, G.S.2    Van Der Spek, J.A.3    Bras, W.4
  • 32
    • 77950349274 scopus 로고    scopus 로고
    • Stability of metal oxide nanoparticles in aqueous solutions
    • 1:CAS:528:DC%2BC3cXisVeit7w%3D 20057098
    • Tso CP, Zhung CM, Shih YH, Tseng YM, Wu SC, Doong RA. Stability of metal oxide nanoparticles in aqueous solutions. Water Sci Technol. 2010;61(1):127-33.
    • (2010) Water Sci Technol , vol.61 , Issue.1 , pp. 127-133
    • Tso, C.P.1    Zhung, C.M.2    Shih, Y.H.3    Tseng, Y.M.4    Wu, S.C.5    Doong, R.A.6
  • 33
    • 84866048070 scopus 로고    scopus 로고
    • Nanoparticles and their interactions with the dermal barrier
    • 1:CAS:528:DC%2BD1MXhsFOqt7bN 20592791 2835875
    • Schneider M, Stracke F, Hansen S, Schaefer UF. Nanoparticles and their interactions with the dermal barrier. Dermatoendocrinol. 2009;1(4):197-206.
    • (2009) Dermatoendocrinol , vol.1 , Issue.4 , pp. 197-206
    • Schneider, M.1    Stracke, F.2    Hansen, S.3    Schaefer, U.F.4
  • 34
    • 75549084961 scopus 로고    scopus 로고
    • Nanotechnology and the transdermal route: A state of the art review and critical appraisal
    • 1:CAS:528:DC%2BC3cXht1Kls7w%3D 19850095
    • Cevc G, Vierl U. Nanotechnology and the transdermal route: a state of the art review and critical appraisal. J Control Release. 2010;141(3):277-99.
    • (2010) J Control Release , vol.141 , Issue.3 , pp. 277-299
    • Cevc, G.1    Vierl, U.2
  • 35
    • 33846905467 scopus 로고    scopus 로고
    • Lipid vesicles for skin delivery of drugs: Reviewing three decades of research
    • 1:CAS:528:DC%2BD2sXhvVSlu74%3D 17222523
    • Elsayed MMA, Abdallah OY, Naggar VF, Khalafallah NM. Lipid vesicles for skin delivery of drugs: reviewing three decades of research. Int J Pharm. 2007;332(1-2):1.
    • (2007) Int J Pharm , vol.332 , Issue.1-2 , pp. 1
    • Elsayed, M.M.A.1    Abdallah, O.Y.2    Naggar, V.F.3    Khalafallah, N.M.4
  • 36
    • 80755125469 scopus 로고    scopus 로고
    • Liposomal systems as drug delivery vehicles for dermal and transdermal applications
    • 1:CAS:528:DC%2BC3MXhtlGltrvJ 21805180
    • Pierre MB, Dos Santos Miranda Costa I. Liposomal systems as drug delivery vehicles for dermal and transdermal applications. Arch Dermatol Res. 2011;303(9):607-21.
    • (2011) Arch Dermatol Res , vol.303 , Issue.9 , pp. 607-621
    • Pierre, M.B.1    Dos Santos Miranda Costa, I.2
  • 38
    • 21244475599 scopus 로고    scopus 로고
    • Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: A randomized controlled trial
    • Taddio A, Soin HK, Schuh S, Koren G, Scolnik D. Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: a randomized controlled trial. Can Med Assoc J. 2005;172(13):1691-5.
    • (2005) Can Med Assoc J , vol.172 , Issue.13 , pp. 1691-1695
    • Taddio, A.1    Soin, H.K.2    Schuh, S.3    Koren, G.4    Scolnik, D.5
  • 39
    • 14844292727 scopus 로고    scopus 로고
    • Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by \SOD\ in Transfersomes
    • 15763624
    • Simões SI, Delgado TC, Lopes RM, Jesus S, Ferreira AA, Morais JA, et al. Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by \SOD\ in Transfersomes. J Control Release. 2005;103(2):419.
    • (2005) J Control Release , vol.103 , Issue.2 , pp. 419
    • Simões, S.I.1    Delgado, T.C.2    Lopes, R.M.3    Jesus, S.4    Ferreira, A.A.5    Morais, J.A.6
  • 40
    • 23744464011 scopus 로고    scopus 로고
    • Ethosomes for skin delivery of ammonium glycyrrhizinate: In vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers
    • 1:CAS:528:DC%2BD2MXntlShs7w%3D 15935505
    • Paolino D, Lucania G, Mardente D, Alhaique F, Fresta M. Ethosomes for skin delivery of ammonium glycyrrhizinate: in vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers. J Control Release. 2005;106(1):99-110.
    • (2005) J Control Release , vol.106 , Issue.1 , pp. 99-110
    • Paolino, D.1    Lucania, G.2    Mardente, D.3    Alhaique, F.4    Fresta, M.5
  • 41
    • 33645075722 scopus 로고    scopus 로고
    • Effect of preparation technique on the properties of liposomes encapsulating ketoprofen-cyclodextrin complexes aimed for transdermal delivery
    • 1:CAS:528:DC%2BD28XisFeqtLo%3D 16469460
    • Maestrelli F, González-Rodríguez ML, Rabasco AM, Mura P. Effect of preparation technique on the properties of liposomes encapsulating ketoprofen-cyclodextrin complexes aimed for transdermal delivery. Int J Pharm. 2006;312(1-2):53.
    • (2006) Int J Pharm , vol.312 , Issue.1-2 , pp. 53
    • Maestrelli, F.1    González-Rodríguez, M.L.2    Rabasco, A.M.3    Mura, P.4
  • 42
    • 34547905035 scopus 로고    scopus 로고
    • Lipid nanoparticles for improved topical application of drugs for skin diseases
    • 17544165
    • Schäfer-Korting M, Mehnert W, Korting HC. Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv Drug Deliv Rev. 2007;59(6):427-43.
    • (2007) Adv Drug Deliv Rev , vol.59 , Issue.6 , pp. 427-443
    • Schäfer-Korting, M.1    Mehnert, W.2    Korting, H.C.3
  • 43
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • 12460720
    • Müller RH, Radtke M, Wissing SA. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv Drug Deliv Rev. 2002;54(Supplement):S131.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. S131
    • Müller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 44
    • 33745518414 scopus 로고    scopus 로고
    • 40 nm, but not 750 or 1,500 nm, nanoparticles enter epidermal CD1a + Cells after transcutaneous application on human skin
    • 1:CAS:528:DC%2BD28Xls1Ghtrs%3D 16614727
    • Vogt A, Combadiere B, Hadam S, Stieler KM, Lademann J, Schaefer H, et al. 40 nm, but not 750 or 1,500 nm, nanoparticles enter epidermal CD1a + Cells after transcutaneous application on human skin. J Invest Dermatol. 2006;126(6):1316-22.
    • (2006) J Invest Dermatol , vol.126 , Issue.6 , pp. 1316-1322
    • Vogt, A.1    Combadiere, B.2    Hadam, S.3    Stieler, K.M.4    Lademann, J.5    Schaefer, H.6
  • 46
    • 84895435428 scopus 로고    scopus 로고
    • Overcoming the cutaneous barrier with microemulsions
    • 24590260 3978525
    • Lopes LB. Overcoming the cutaneous barrier with microemulsions. Pharmaceutics. 2014;6(1):52-77.
    • (2014) Pharmaceutics , vol.6 , Issue.1 , pp. 52-77
    • Lopes, L.B.1
  • 47
    • 84876484450 scopus 로고    scopus 로고
    • Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases
    • 1:CAS:528:DC%2BC3sXmt1Kltb8%3D 23386536 3631287
    • Zhang Z, Tsai PC, Ramezanli T, Michniak-Kohn B. Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013;5(3):205-18.
    • (2013) Wiley Interdiscip Rev Nanomed Nanobiotechnol , vol.5 , Issue.3 , pp. 205-218
    • Zhang, Z.1    Tsai, P.C.2    Ramezanli, T.3    Michniak-Kohn, B.4
  • 48
    • 33745928725 scopus 로고    scopus 로고
    • Retinol-encapsulated low molecular water-soluble chitosan nanoparticles
    • 1:CAS:528:DC%2BD28XmvFKgurk%3D 16713152
    • Kim DG, Jeong YI, Choi C, Roh SH, Kang SK, Jang MK, et al. Retinol-encapsulated low molecular water-soluble chitosan nanoparticles. Int J Pharm. 2006;319(1-2):130-8.
    • (2006) Int J Pharm , vol.319 , Issue.1-2 , pp. 130-138
    • Kim, D.G.1    Jeong, Y.I.2    Choi, C.3    Roh, S.H.4    Kang, S.K.5    Jang, M.K.6
  • 49
    • 75749149383 scopus 로고    scopus 로고
    • Chitosan-tripolyphosphate nanoparticles as a possible skin drug delivery system for aciclovir with enhanced stability
    • 1:CAS:528:DC%2BC3cXitFGqsr0%3D 19958582
    • Hasanovic A, Zehl M, Reznicek G, Valenta C. Chitosan-tripolyphosphate nanoparticles as a possible skin drug delivery system for aciclovir with enhanced stability. J Pharm Pharmacol. 2009;61(12):1609-16.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.12 , pp. 1609-1616
    • Hasanovic, A.1    Zehl, M.2    Reznicek, G.3    Valenta, C.4
  • 50
    • 80052929308 scopus 로고    scopus 로고
    • Enhanced transdermal delivery of indomethacin-loaded PLGA nanoparticles by iontophoresis
    • 1:CAS:528:DC%2BC3MXhtF2gsLvP 21885261
    • Tomoda K, Terashima H, Suzuki K, Inagi T, Terada H, Makino K. Enhanced transdermal delivery of indomethacin-loaded PLGA nanoparticles by iontophoresis. Colloids Surf, B Biointerfaces. 2011;88(2):706-10.
    • (2011) Colloids Surf, B Biointerfaces , vol.88 , Issue.2 , pp. 706-710
    • Tomoda, K.1    Terashima, H.2    Suzuki, K.3    Inagi, T.4    Terada, H.5    Makino, K.6
  • 51
    • 83355166267 scopus 로고    scopus 로고
    • Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs
    • 1:CAS:528:DC%2BC3MXhsF2lt7zE 22118820 3242008
    • Shah PP, Desai PR, Patel AR, Singh MS. Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs. Biomaterials. 2012;33(5):1607-17.
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1607-1617
    • Shah, P.P.1    Desai, P.R.2    Patel, A.R.3    Singh, M.S.4
  • 52
    • 0036851496 scopus 로고    scopus 로고
    • Influence of microemulsions on cutaneous drug delivery
    • 1:CAS:528:DC%2BD38XpsVOhtrg%3D 12460717
    • Kreilgaard M. Influence of microemulsions on cutaneous drug delivery. Adv Drug Deliv Rev. 2002;54(Supplement):S77-98.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. S77-S98
    • Kreilgaard, M.1
  • 53
    • 0035912972 scopus 로고    scopus 로고
    • Topical transfection using plasmid DNA in a water-in-oil nanoemulsion
    • 1:CAS:528:DC%2BD3MXktVGktLo%3D 11397564
    • Wu H, Ramachandran C, Bielinska AU, Kingzett K, Sun R, Weiner ND, et al. Topical transfection using plasmid DNA in a water-in-oil nanoemulsion. Int J Pharm. 2001;221(1-2):23-34.
    • (2001) Int J Pharm , vol.221 , Issue.1-2 , pp. 23-34
    • Wu, H.1    Ramachandran, C.2    Bielinska, A.U.3    Kingzett, K.4    Sun, R.5    Weiner, N.D.6
  • 55
    • 76649095259 scopus 로고    scopus 로고
    • Topical delivery of lycopene using microemulsions: Enhanced skin penetration and tissue antioxidant activity
    • 1:CAS:528:DC%2BC3cXmvVGgsw%3D%3D 19798758
    • Lopes LB, VanDeWall H, Li HT, Venugopal V, Li HK, Naydin S, et al. Topical delivery of lycopene using microemulsions: enhanced skin penetration and tissue antioxidant activity. J Pharm Sci. 2010;99(3):1346-57.
    • (2010) J Pharm Sci , vol.99 , Issue.3 , pp. 1346-1357
    • Lopes, L.B.1    VanDeWall, H.2    Li, H.T.3    Venugopal, V.4    Li, H.K.5    Naydin, S.6
  • 56
  • 57
    • 84864396879 scopus 로고    scopus 로고
    • Quantum dots for biophotonics
    • 1:CAS:528:DC%2BC38XhtFCqsbjJ 22896767 3418930
    • Yong KT. Quantum dots for biophotonics. Theranostics. 2012;2(7):629-30.
    • (2012) Theranostics , vol.2 , Issue.7 , pp. 629-630
    • Yong, K.T.1
  • 59
    • 41549109750 scopus 로고    scopus 로고
    • Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes
    • 1:CAS:528:DC%2BD1cXks12nsbg%3D 18261754
    • Zhang LW, Yu WW, Colvin VL, Monteiro-Riviere NA. Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicol Appl Pharmacol. 2008;228(2):200-11.
    • (2008) Toxicol Appl Pharmacol , vol.228 , Issue.2 , pp. 200-211
    • Zhang, L.W.1    Yu, W.W.2    Colvin, V.L.3    Monteiro-Riviere, N.A.4
  • 60
    • 33645800783 scopus 로고    scopus 로고
    • Penetration of Intact skin by quantum dots with diverse physicochemical properties
    • 1:CAS:528:DC%2BD28Xjtlamtbs%3D 16443688
    • Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA. Penetration of Intact skin by quantum dots with diverse physicochemical properties. Toxicol Sci. 2006;91(1):159-65.
    • (2006) Toxicol Sci , vol.91 , Issue.1 , pp. 159-165
    • Ryman-Rasmussen, J.P.1    Riviere, J.E.2    Monteiro-Riviere, N.A.3
  • 61
    • 44849084746 scopus 로고    scopus 로고
    • Assessment of quantum dot penetration into intact, tape-stripped, abraded and flexed rat skin
    • 18523414
    • Zhang LW, Monteiro-Riviere NA. Assessment of quantum dot penetration into intact, tape-stripped, abraded and flexed rat skin. Skin Pharmacol Physiol. 2008;21(3):166-80.
    • (2008) Skin Pharmacol Physiol , vol.21 , Issue.3 , pp. 166-180
    • Zhang, L.W.1    Monteiro-Riviere, N.A.2
  • 62
    • 36048994076 scopus 로고    scopus 로고
    • In vitro and in vivo transdermal delivery capacity of quantum dots through mouse skin
    • Chu MQ, Wu Q, Wang JX, Hou SK, Miao Y, Peng JL, et al. In vitro and in vivo transdermal delivery capacity of quantum dots through mouse skin. Nanotechnology. 2007;18(45):455103.
    • (2007) Nanotechnology , vol.18 , Issue.45
    • Chu, M.Q.1    Wu, Q.2    Wang, J.X.3    Hou, S.K.4    Miao, Y.5    Peng, J.L.6
  • 63
    • 33947322486 scopus 로고    scopus 로고
    • Grey Goo on the Skin? Nanotechnology, cosmetic and sunscreen safety
    • 1:CAS:528:DC%2BD2sXkvVWgtrY%3D 17453934
    • Nohynek GJ, Lademann J, Ribaud C, Roberts MS. Grey Goo on the Skin? Nanotechnology, cosmetic and sunscreen safety. Crit Rev Toxicol. 2007;37(3):251-77.
    • (2007) Crit Rev Toxicol , vol.37 , Issue.3 , pp. 251-277
    • Nohynek, G.J.1    Lademann, J.2    Ribaud, C.3    Roberts, M.S.4
  • 64
    • 84866011206 scopus 로고    scopus 로고
    • Measurement of skin permeation/Penetration of nanoparticles for their safety evaluation
    • 1:CAS:528:DC%2BC38XhslSmsLzF 22975498
    • Kimura E, Kawano Y, Todo H, Ikarashi Y, Sugibayashi K. Measurement of skin permeation/Penetration of nanoparticles for their safety evaluation. Biol Pharm Bull. 2012;35(9):1476-86.
    • (2012) Biol Pharm Bull , vol.35 , Issue.9 , pp. 1476-1486
    • Kimura, E.1    Kawano, Y.2    Todo, H.3    Ikarashi, Y.4    Sugibayashi, K.5
  • 65
    • 0037584828 scopus 로고    scopus 로고
    • Some properties of fullerenes and carbon nanotubes
    • 1:CAS:528:DC%2BD3MXltFWlsLw%3D
    • Byszewski P, Klusek Z. Some properties of fullerenes and carbon nanotubes. Opto-Electron Rev. 2001;9(2):203-10.
    • (2001) Opto-Electron Rev , vol.9 , Issue.2 , pp. 203-210
    • Byszewski, P.1    Klusek, Z.2
  • 66
    • 33846883504 scopus 로고    scopus 로고
    • Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin
    • 1:CAS:528:DC%2BD28Xht1OmsL7I 17212456
    • Rouse JG, Yang J, Ryman-Rasmussen J, Barron AR, Monteiro-Riviere N. Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin. Nano Lett. 2007;7(1):155-60.
    • (2007) Nano Lett , vol.7 , Issue.1 , pp. 155-160
    • Rouse, J.G.1    Yang, J.2    Ryman-Rasmussen, J.3    Barron, A.R.4    Monteiro-Riviere, N.5
  • 67
    • 84893711078 scopus 로고    scopus 로고
    • Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma
    • 1:CAS:528:DC%2BC2cXptFGitg%3D%3D 24424208
    • Siu KS, Chen D, Zheng X, Zhang X, Johnston N, Liu Y, et al. Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma. Biomaterials. 2014;35(10):3435-42.
    • (2014) Biomaterials , vol.35 , Issue.10 , pp. 3435-3442
    • Siu, K.S.1    Chen, D.2    Zheng, X.3    Zhang, X.4    Johnston, N.5    Liu, Y.6
  • 68
    • 78049484505 scopus 로고    scopus 로고
    • Carbon nanotubes for transdermal drug delivery
    • 1:CAS:528:DC%2BC3cXhtlGms7zF 20690793
    • Degim IT, Burgess DJ, Papadimitrakopoulos F. Carbon nanotubes for transdermal drug delivery. J Microencapsul. 2010;27(8):669-81.
    • (2010) J Microencapsul , vol.27 , Issue.8 , pp. 669-681
    • Degim, I.T.1    Burgess, D.J.2    Papadimitrakopoulos, F.3
  • 69
    • 47349128121 scopus 로고    scopus 로고
    • Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: Potential for enhanced topical photodynamic therapy
    • 1:CAS:528:DC%2BD1cXovFOnu7Y%3D 18556084
    • Donnelly RF, Morrow DIJ, McCarron PA, Woolfson AD, Morrissey A, Juzenas P, et al. Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy. J Control Release. 2008;129(3):154-62.
    • (2008) J Control Release , vol.129 , Issue.3 , pp. 154-162
    • Donnelly, R.F.1    Morrow, D.I.J.2    McCarron, P.A.3    Woolfson, A.D.4    Morrissey, A.5    Juzenas, P.6
  • 70
    • 84901745519 scopus 로고    scopus 로고
    • Current advances in the fabrication of microneedles for transdermal delivery
    • 1:CAS:528:DC%2BC2cXpvFWktrw%3D 24806483
    • Indermun S, Luttge R, Choonara YE, Kumar P, du Toit LC, Modi G, et al. Current advances in the fabrication of microneedles for transdermal delivery. J Control Release. 2014;185:130-8.
    • (2014) J Control Release , vol.185 , pp. 130-138
    • Indermun, S.1    Luttge, R.2    Choonara, Y.E.3    Kumar, P.4    Du Toit, L.C.5    Modi, G.6
  • 71
    • 77349091986 scopus 로고    scopus 로고
    • Super-short solid silicon microneedles for transdermal drug delivery applications
    • 1:CAS:528:DC%2BC3cXivVOltLk%3D 20096759
    • Li WZ, Huo MR, Zhou JP, Zhou YQ, Hao BH, Liu T, et al. Super-short solid silicon microneedles for transdermal drug delivery applications. Int J Pharm. 2010;389(1-2):122-9.
    • (2010) Int J Pharm , vol.389 , Issue.1-2 , pp. 122-129
    • Li, W.Z.1    Huo, M.R.2    Zhou, J.P.3    Zhou, Y.Q.4    Hao, B.H.5    Liu, T.6
  • 72
    • 84904206844 scopus 로고    scopus 로고
    • Structural characterization and in-vivo reliability evaluation of silicon microneedles
    • 24487507
    • O'Mahony C. Structural characterization and in-vivo reliability evaluation of silicon microneedles. Biomed Microdevices. 2014;16(3):333-43.
    • (2014) Biomed Microdevices , vol.16 , Issue.3 , pp. 333-343
    • O'Mahony, C.1
  • 73
    • 58349092641 scopus 로고    scopus 로고
    • Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer
    • 1:CAS:528:DC%2BD1MXislamsL4%3D 18764907
    • Donnelly RF, Morrow DI, McCarron PA, Woolfson AD, Morrissey A, Juzenas P, et al. Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer. Photochem Photobiol. 2009;85(1):195-204.
    • (2009) Photochem Photobiol , vol.85 , Issue.1 , pp. 195-204
    • Donnelly, R.F.1    Morrow, D.I.2    McCarron, P.A.3    Woolfson, A.D.4    Morrissey, A.5    Juzenas, P.6
  • 74
    • 48149083798 scopus 로고    scopus 로고
    • Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein
    • 1:CAS:528:DC%2BD1cXpt1GqsLY%3D 18411045
    • Oh JH, Park HH, Do KY, Han M, Hyun DH, Kim CG, et al. Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein. Eur J Pharm Biopharm. 2008;69(3):1040-5.
    • (2008) Eur J Pharm Biopharm , vol.69 , Issue.3 , pp. 1040-1045
    • Oh, J.H.1    Park, H.H.2    Do, K.Y.3    Han, M.4    Hyun, D.H.5    Kim, C.G.6
  • 75
    • 0344270926 scopus 로고    scopus 로고
    • Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies
    • 1:CAS:528:DC%2BD3sXpsFGisrw%3D 14623977 283494
    • McAllister DV, Wang PM, Davis SP, Park JH, Canatella PJ, Allen MG, et al. Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies. Proc Natl Acad Sci U S A. 2003;100(24):13755-60.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.24 , pp. 13755-13760
    • McAllister, D.V.1    Wang, P.M.2    Davis, S.P.3    Park, J.H.4    Canatella, P.J.5    Allen, M.G.6
  • 76
    • 41149125953 scopus 로고    scopus 로고
    • Microneedles permit transdermal delivery of a skin-impermeant medication to humans
    • 1:CAS:528:DC%2BD1cXisVWmsbg%3D 18250310 2538880
    • Wermeling DP, Banks SL, Hudson DA, Gill HS, Gupta J, Prausnitz MR, et al. Microneedles permit transdermal delivery of a skin-impermeant medication to humans. Proc Natl Acad Sci U S A. 2008;105(6):2058-63.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.6 , pp. 2058-2063
    • Wermeling, D.P.1    Banks, S.L.2    Hudson, D.A.3    Gill, H.S.4    Gupta, J.5    Prausnitz, M.R.6
  • 77
    • 84855830076 scopus 로고    scopus 로고
    • Simultaneous basal-bolus delivery of fast-acting insulin and its significance in diabetes management
    • 1:CAS:528:DC%2BC38Xos12gtw%3D%3D 21703994
    • Qin G, Gao Y, Wu Y, Zhang S, Qiu Y, Li F, et al. Simultaneous basal-bolus delivery of fast-acting insulin and its significance in diabetes management. Nanomedicine. 2012;8(2):221-7.
    • (2012) Nanomedicine , vol.8 , Issue.2 , pp. 221-227
    • Qin, G.1    Gao, Y.2    Wu, Y.3    Zhang, S.4    Qiu, Y.5    Li, F.6
  • 78
    • 33846492454 scopus 로고    scopus 로고
    • Coated microneedles for transdermal delivery
    • 1:CAS:528:DC%2BD2sXht1Cmsbs%3D 17169459 1853346
    • Gill HS, Prausnitz MR. Coated microneedles for transdermal delivery. J Control Release. 2007;117(2):227-37.
    • (2007) J Control Release , vol.117 , Issue.2 , pp. 227-237
    • Gill, H.S.1    Prausnitz, M.R.2
  • 79
    • 84859488472 scopus 로고    scopus 로고
    • Coated microneedle arrays for transcutaneous delivery of live virus vaccines
    • 1:CAS:528:DC%2BC38XhsFSgurc%3D 22245683
    • Vrdoljak A, McGrath MG, Carey JB, Draper SJ, Hill AV, O'Mahony C, et al. Coated microneedle arrays for transcutaneous delivery of live virus vaccines. J Control Release. 2012;159(1):34-42.
    • (2012) J Control Release , vol.159 , Issue.1 , pp. 34-42
    • Vrdoljak, A.1    McGrath, M.G.2    Carey, J.B.3    Draper, S.J.4    Hill, A.V.5    O'Mahony, C.6
  • 80
    • 53249119663 scopus 로고    scopus 로고
    • Transdermal drug delivery by coated microneedles: Geometry effects on effective skin thickness and drug permeability
    • 1:CAS:528:DC%2BD1cXhtlKhsLzI
    • Davidson A, Al-Qallaf B, Das DB. Transdermal drug delivery by coated microneedles: geometry effects on effective skin thickness and drug permeability. Chem Eng Res Des. 2008;86(11):1196-206.
    • (2008) Chem Eng Res des , vol.86 , Issue.11 , pp. 1196-1206
    • Davidson, A.1    Al-Qallaf, B.2    Das, D.B.3
  • 81
    • 3042556333 scopus 로고    scopus 로고
    • Transdermal delivery of desmopressin using a coated microneedle array patch system
    • 1:CAS:528:DC%2BD2cXkvF2itLs%3D 15212882
    • Cormier M, Johnson B, Ameri M, Nyam K, Libiran L, Zhang DD, et al. Transdermal delivery of desmopressin using a coated microneedle array patch system. J Control Release. 2004;97(3):503-11.
    • (2004) J Control Release , vol.97 , Issue.3 , pp. 503-511
    • Cormier, M.1    Johnson, B.2    Ameri, M.3    Nyam, K.4    Libiran, L.5    Zhang, D.D.6
  • 82
    • 78649905693 scopus 로고    scopus 로고
    • Formulation of microneedles coated with influenza virus-like particle vaccine
    • 1:CAS:528:DC%2BC3cXhsFemsLfK 20676947 2974157
    • Kim YC, Quan FS, Compans RW, Kang SM, Prausnitz MR. Formulation of microneedles coated with influenza virus-like particle vaccine. AAPS PharmSciTech. 2010;11(3):1193-201.
    • (2010) AAPS PharmSciTech , vol.11 , Issue.3 , pp. 1193-1201
    • Kim, Y.C.1    Quan, F.S.2    Compans, R.W.3    Kang, S.M.4    Prausnitz, M.R.5
  • 83
    • 70349322619 scopus 로고    scopus 로고
    • Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
    • 1:CAS:528:DC%2BD1MXhtFOkt7bO 19577597
    • Chen X, Prow TW, Crichton ML, Jenkins DW, Roberts MS, Frazer IH, et al. Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. J Control Release. 2009;139(3):212-20.
    • (2009) J Control Release , vol.139 , Issue.3 , pp. 212-220
    • Chen, X.1    Prow, T.W.2    Crichton, M.L.3    Jenkins, D.W.4    Roberts, M.S.5    Frazer, I.H.6
  • 84
    • 84873481790 scopus 로고    scopus 로고
    • Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept
    • 1:CAS:528:DC%2BC3sXjsFOlsLc%3D 23313112 3594125
    • Chong RH, Gonzalez-Gonzalez E, Lara MF, Speaker TJ, Contag CH, Kaspar RL, et al. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. J Control Release. 2013;166(3):211-9.
    • (2013) J Control Release , vol.166 , Issue.3 , pp. 211-219
    • Chong, R.H.1    Gonzalez-Gonzalez, E.2    Lara, M.F.3    Speaker, T.J.4    Contag, C.H.5    Kaspar, R.L.6
  • 85
    • 84865306956 scopus 로고    scopus 로고
    • Two-layered dissolving microneedles formulated with intermediate-acting insulin
    • 1:CAS:528:DC%2BC38Xht12jtrzK 22750407
    • Ito Y, Hirono M, Fukushima K, Sugioka N, Takada K. Two-layered dissolving microneedles formulated with intermediate-acting insulin. Int J Pharm. 2012;436(1-2):387-93.
    • (2012) Int J Pharm , vol.436 , Issue.1-2 , pp. 387-393
    • Ito, Y.1    Hirono, M.2    Fukushima, K.3    Sugioka, N.4    Takada, K.5
  • 86
    • 84864575139 scopus 로고    scopus 로고
    • The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin
    • 1:CAS:528:DC%2BC38XhtFCitrfK 22634072
    • Liu S, Jin MN, Quan YS, Kamiyama F, Katsumi H, Sakane T, et al. The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin. J Control Release. 2012;161(3):933-41.
    • (2012) J Control Release , vol.161 , Issue.3 , pp. 933-941
    • Liu, S.1    Jin, M.N.2    Quan, Y.S.3    Kamiyama, F.4    Katsumi, H.5    Sakane, T.6
  • 87
    • 84867839667 scopus 로고    scopus 로고
    • Laser-engineered dissolving microneedles for active transdermal delivery of nadroparin calcium
    • 1:CAS:528:DC%2BC38Xht1Gks7rO 22836025 4119960
    • Gomaa YA, Garland MJ, McInnes F, El-Khordagui LK, Wilson C, Donnelly R. Laser-engineered dissolving microneedles for active transdermal delivery of nadroparin calcium. Eur J Pharm Biopharm. 2012;82(2):299-307.
    • (2012) Eur J Pharm Biopharm , vol.82 , Issue.2 , pp. 299-307
    • Gomaa, Y.A.1    Garland, M.J.2    McInnes, F.3    El-Khordagui, L.K.4    Wilson, C.5    Donnelly, R.6
  • 88
    • 84856325900 scopus 로고    scopus 로고
    • Antigen-loaded dissolving microneedle array as a novel tool for percutaneous vaccination
    • 1:CAS:528:DC%2BC38XhsVCjsrY%3D 22172508
    • Naito S, Ito Y, Kiyohara T, Kataoka M, Ochiai M, Takada K. Antigen-loaded dissolving microneedle array as a novel tool for percutaneous vaccination. Vaccine. 2012;30(6):1191-7.
    • (2012) Vaccine , vol.30 , Issue.6 , pp. 1191-1197
    • Naito, S.1    Ito, Y.2    Kiyohara, T.3    Kataoka, M.4    Ochiai, M.5    Takada, K.6
  • 89
    • 84862629947 scopus 로고    scopus 로고
    • A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens
    • 1:CAS:528:DC%2BC38Xos1eitr4%3D 22306332
    • Matsuo K, Yokota Y, Zhai Y, Quan YS, Kamiyama F, Mukai Y, et al. A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens. J Control Release. 2012;161(1):10-7.
    • (2012) J Control Release , vol.161 , Issue.1 , pp. 10-17
    • Matsuo, K.1    Yokota, Y.2    Zhai, Y.3    Quan, Y.S.4    Kamiyama, F.5    Mukai, Y.6
  • 90
    • 84861977586 scopus 로고    scopus 로고
    • Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza
    • 1:CAS:528:DC%2BC38XmtlKitLo%3D 22516091
    • Matsuo K, Hirobe S, Yokota Y, Ayabe Y, Seto M, Quan YS, et al. Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza. J Control Release. 2012;160(3):495-501.
    • (2012) J Control Release , vol.160 , Issue.3 , pp. 495-501
    • Matsuo, K.1    Hirobe, S.2    Yokota, Y.3    Ayabe, Y.4    Seto, M.5    Quan, Y.S.6
  • 91
    • 84899919641 scopus 로고    scopus 로고
    • Hydrogel-forming and dissolving microneedles for enhanced delivery of photosensitizers and precursors
    • 1:CAS:528:DC%2BC2cXntFCnsbY%3D 24215482 4119997
    • Donnelly RF, Morrow DI, McCrudden MT, Alkilani AZ, Vicente-Pérez EM, O'Mahony C, et al. Hydrogel-forming and dissolving microneedles for enhanced delivery of photosensitizers and precursors. Photochem Photobiol. 2014;90(3):641-7.
    • (2014) Photochem Photobiol , vol.90 , Issue.3 , pp. 641-647
    • Donnelly, R.F.1    Morrow, D.I.2    McCrudden, M.T.3    Alkilani, A.Z.4    Vicente-Pérez, E.M.5    O'Mahony, C.6
  • 92
    • 84895558909 scopus 로고    scopus 로고
    • Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs
    • 1:CAS:528:DC%2BC2cXkvVGksLw%3D 24556420 4034161
    • McCrudden MT, Alkilani AZ, McCrudden CM, McAlister E, McCarthy HO, Woolfson AD, et al. Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs. J Control Release. 2014;180:71-80.
    • (2014) J Control Release , vol.180 , pp. 71-80
    • McCrudden, M.T.1    Alkilani, A.Z.2    McCrudden, C.M.3    McAlister, E.4    McCarthy, H.O.5    Woolfson, A.D.6
  • 93
    • 84859501688 scopus 로고    scopus 로고
    • Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery
    • 1:CAS:528:DC%2BC38XltlKmsbY%3D 22265694 4119959
    • Garland MJ, Caffarel-Salvador E, Migalska K, Woolfson AD, Donnelly RF. Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery. J Control Release. 2012;159(1):52-9.
    • (2012) J Control Release , vol.159 , Issue.1 , pp. 52-59
    • Garland, M.J.1    Caffarel-Salvador, E.2    Migalska, K.3    Woolfson, A.D.4    Donnelly, R.F.5
  • 94
    • 39749199632 scopus 로고    scopus 로고
    • Painless drug delivery through microneedle-based transdermal patches featuring active infusion
    • 18334398
    • Roxhed N, Samel B, Nordquist L, Griss P, Stemme G. Painless drug delivery through microneedle-based transdermal patches featuring active infusion. IEEE Trans Biomed Eng. 2008;55(3):1063-71.
    • (2008) IEEE Trans Biomed Eng , vol.55 , Issue.3 , pp. 1063-1071
    • Roxhed, N.1    Samel, B.2    Nordquist, L.3    Griss, P.4    Stemme, G.5
  • 95
    • 0038547999 scopus 로고    scopus 로고
    • Characterization of surface micromachined metallic microneedles
    • Chandrasekaran S, Frazier AB. Characterization of surface micromachined metallic microneedles. J Microelectromech Syst. 2003;12(3):289-95.
    • (2003) J Microelectromech Syst , vol.12 , Issue.3 , pp. 289-295
    • Chandrasekaran, S.1    Frazier, A.B.2
  • 96
    • 33646148967 scopus 로고    scopus 로고
    • Precise microinjection into skin using hollow microneedles
    • 1:CAS:528:DC%2BD28XjsFSqsr4%3D 16484988
    • Wang PM, Cornwell M, Hill J, Prausnitz MR. Precise microinjection into skin using hollow microneedles. J Invest Dermatol. 2006;126(5):1080-7.
    • (2006) J Invest Dermatol , vol.126 , Issue.5 , pp. 1080-1087
    • Wang, P.M.1    Cornwell, M.2    Hill, J.3    Prausnitz, M.R.4
  • 97
    • 33847301400 scopus 로고    scopus 로고
    • Polymeric microneedle fabrication using a microinjection molding technique
    • 1:CAS:528:DC%2BD2sXitVOmt7c%3D
    • Sammoura F, Kang JJ, Heo YM, Jung TS, Lin LW. Polymeric microneedle fabrication using a microinjection molding technique. Microsyst Technol. 2007;13(5-6):517-22.
    • (2007) Microsyst Technol , vol.13 , Issue.5-6 , pp. 517-522
    • Sammoura, F.1    Kang, J.J.2    Heo, Y.M.3    Jung, T.S.4    Lin, L.W.5
  • 99
  • 100
    • 84878008698 scopus 로고    scopus 로고
    • Hydrogel-forming microneedle arrays exhibit antimicrobial properties: Potential for enhanced patient safety
    • 1:CAS:528:DC%2BC3sXosFOmsLc%3D 23644043 4119957
    • Donnelly RF, Singh TR, Alkilani AZ, McCrudden MT, O'Neill S, O'Mahony C, et al. Hydrogel-forming microneedle arrays exhibit antimicrobial properties: potential for enhanced patient safety. Int J Pharm. 2013;451(1-2):76-91.
    • (2013) Int J Pharm , vol.451 , Issue.1-2 , pp. 76-91
    • Donnelly, R.F.1    Singh, T.R.2    Alkilani, A.Z.3    McCrudden, M.T.4    O'Neill, S.5    O'Mahony, C.6
  • 101
  • 102
    • 84910020396 scopus 로고    scopus 로고
    • Hydrogel-forming microneedles prepared from "Super Swelling" polymers combined with lyophilised wafers for transdermal drug delivery
    • 25360806 4216095
    • Donnelly RF, McCrudden MTC, Zaid Alkilani A, Larrañeta E, McAlister E, Courtenay AJ, et al. Hydrogel-forming microneedles prepared from "Super Swelling" polymers combined with lyophilised wafers for transdermal drug delivery. PLoS One. 2014;9(10):e111547.
    • (2014) PLoS One , vol.9 , Issue.10
    • Donnelly, R.F.1    McCrudden, M.T.C.2    Zaid Alkilani, A.3    Larrañeta, E.4    McAlister, E.5    Courtenay, A.J.6
  • 104
    • 84958780279 scopus 로고    scopus 로고
    • Hydrogel microneedle arrays for transdermal drug delivery
    • 1:CAS:528:DC%2BC2cXhs12qtbbJ
    • Hong X, Wu Z, Chen L, Wu F, Wei L, Yuan W. Hydrogel microneedle arrays for transdermal drug delivery. Nano-Micro Lett. 2014;6(3):191-9.
    • (2014) Nano-Micro Lett , vol.6 , Issue.3 , pp. 191-199
    • Hong, X.1    Wu, Z.2    Chen, L.3    Wu, F.4    Wei, L.5    Yuan, W.6
  • 106
    • 57849157314 scopus 로고    scopus 로고
    • Microneedle mediated delivery of nanoparticles into human skin
    • 1:CAS:528:DC%2BD1cXhsFCjurvE 18812218
    • Coulman SA, Anstey A, Gateley C, Morrissey A, McLoughlin P, Allender C, et al. Microneedle mediated delivery of nanoparticles into human skin. Int J Pharm. 2009;366(1-2):190-200.
    • (2009) Int J Pharm , vol.366 , Issue.1-2 , pp. 190-200
    • Coulman, S.A.1    Anstey, A.2    Gateley, C.3    Morrissey, A.4    McLoughlin, P.5    Allender, C.6
  • 107
    • 78349312540 scopus 로고    scopus 로고
    • Penetration and distribution of PLGA nanoparticles in the human skin treated with microneedles
    • 1:CAS:528:DC%2BC3cXhsVWhu7%2FO 20932886
    • Zhang W, Gao J, Zhu Q, Zhang M, Ding X, Wang X, et al. Penetration and distribution of PLGA nanoparticles in the human skin treated with microneedles. Int J Pharm. 2010;402(1-2):205-12.
    • (2010) Int J Pharm , vol.402 , Issue.1-2 , pp. 205-212
    • Zhang, W.1    Gao, J.2    Zhu, Q.3    Zhang, M.4    Ding, X.5    Wang, X.6
  • 109
    • 84883823077 scopus 로고    scopus 로고
    • An experimental study of microneedle-assisted microparticle delivery
    • 1:CAS:528:DC%2BC3sXhtFOiu7%2FI 23893898
    • Zhang D, Das DB, Rielly CD. An experimental study of microneedle-assisted microparticle delivery. J Pharm Sci. 2013;102(10):3632-44.
    • (2013) J Pharm Sci , vol.102 , Issue.10 , pp. 3632-3644
    • Zhang, D.1    Das, D.B.2    Rielly, C.D.3
  • 110
    • 84895919548 scopus 로고    scopus 로고
    • Microneedle assisted micro-particle delivery from gene guns: Experiments using skin-mimicking agarose gel
    • 1:CAS:528:DC%2BC2cXktFOmsQ%3D%3D 24399616
    • Zhang D, Das DB, Rielly CD. Microneedle assisted micro-particle delivery from gene guns: experiments using skin-mimicking agarose gel. J Pharm Sci. 2014;103(2):613-27.
    • (2014) J Pharm Sci , vol.103 , Issue.2 , pp. 613-627
    • Zhang, D.1    Das, D.B.2    Rielly, C.D.3
  • 111
    • 70549084842 scopus 로고    scopus 로고
    • In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery
    • 19347587
    • Häfeli UO, Mokhtari A, Liepmann D, Stoeber B. In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery. Biomed Microdevices. 2009;11(5):943-50.
    • (2009) Biomed Microdevices , vol.11 , Issue.5 , pp. 943-950
    • Häfeli, U.O.1    Mokhtari, A.2    Liepmann, D.3    Stoeber, B.4
  • 112
  • 113
    • 58549106105 scopus 로고    scopus 로고
    • Intrascleral drug delivery to the eye using hollow microneedles
    • 1:CAS:528:DC%2BD1cXhtlWhtbvK 18979189 2900774
    • Jiang J, Moore J, Edelhauser H, Prausnitz M. Intrascleral drug delivery to the eye using hollow microneedles. Pharm Res. 2009;26(2):395-403.
    • (2009) Pharm Res , vol.26 , Issue.2 , pp. 395-403
    • Jiang, J.1    Moore, J.2    Edelhauser, H.3    Prausnitz, M.4
  • 114
    • 78651245667 scopus 로고    scopus 로고
    • Suprachoroidal drug delivery to the back of the eye using hollow microneedles
    • 1:CAS:528:DC%2BC3cXhtFOrtbrO 20857178 3038673
    • Patel SR, Lin AS, Edelhauser HF, Prausnitz MR. Suprachoroidal drug delivery to the back of the eye using hollow microneedles. Pharm Res. 2011;28(1):166-76.
    • (2011) Pharm Res , vol.28 , Issue.1 , pp. 166-176
    • Patel, S.R.1    Lin, A.S.2    Edelhauser, H.F.3    Prausnitz, M.R.4
  • 115
    • 84906094119 scopus 로고    scopus 로고
    • Particle-stabilized emulsion droplets for gravity-mediated targeting in the posterior segment of the eye
    • 1:CAS:528:DC%2BC2cXhtlKjt7%2FF 24652782 4134775
    • Kim YC, Edelhauser HF, Prausnitz MR. Particle-stabilized emulsion droplets for gravity-mediated targeting in the posterior segment of the eye. Adv Healthc Mater. 2014;3(8):1272-82.
    • (2014) Adv Healthc Mater , vol.3 , Issue.8 , pp. 1272-1282
    • Kim, Y.C.1    Edelhauser, H.F.2    Prausnitz, M.R.3
  • 116
    • 78449282148 scopus 로고    scopus 로고
    • Nano-layered microneedles for transcutaneous delivery of polymer nanoparticles and plasmid DNA
    • 1:CAS:528:DC%2BC3cXhsVWmtrnK 20859938 3030257
    • DeMuth PC, Su X, Samuel RE, Hammond PT, Irvine DJ. Nano-layered microneedles for transcutaneous delivery of polymer nanoparticles and plasmid DNA. Adv Mater. 2010;22(43):4851.
    • (2010) Adv Mater , vol.22 , Issue.43 , pp. 4851
    • DeMuth, P.C.1    Su, X.2    Samuel, R.E.3    Hammond, P.T.4    Irvine, D.J.5
  • 117
    • 84930624826 scopus 로고    scopus 로고
    • Biodegradable nanoneedles for localized delivery of nanoparticles in vivo: Exploring the biointerface
    • 1:CAS:528:DC%2BC2MXmtlaktbo%3D 25858596 4733661
    • Chiappini C, Martinez JO, De Rosa E, Almeida CS, Tasciotti E, Stevens MM. Biodegradable nanoneedles for localized delivery of nanoparticles in vivo: exploring the biointerface. ACS Nano. 2015;9(5):5500-9.
    • (2015) ACS Nano , vol.9 , Issue.5 , pp. 5500-5509
    • Chiappini, C.1    Martinez, J.O.2    De Rosa, E.3    Almeida, C.S.4    Tasciotti, E.5    Stevens, M.M.6
  • 118
    • 34250011186 scopus 로고    scopus 로고
    • Sustained-release self-dissolving micropiles for percutaneous absorption of insulin in mice
    • 1:CAS:528:DC%2BD2sXlvFejsLs%3D 17541840
    • Ito Y, Hagiwara E, Saeki A, Sugioka N, Takada K. Sustained-release self-dissolving micropiles for percutaneous absorption of insulin in mice. J Drug Target. 2007;15(5):323-6.
    • (2007) J Drug Target , vol.15 , Issue.5 , pp. 323-326
    • Ito, Y.1    Hagiwara, E.2    Saeki, A.3    Sugioka, N.4    Takada, K.5
  • 119
    • 68949218781 scopus 로고    scopus 로고
    • Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin
    • 1:CAS:528:DC%2BD1MXhtVGrtbrN 19481577
    • Chen H, Zhu H, Zheng J, Mou D, Wan J, Zhang J, et al. Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin. J Control Release. 2009;139(1):63-72.
    • (2009) J Control Release , vol.139 , Issue.1 , pp. 63-72
    • Chen, H.1    Zhu, H.2    Zheng, J.3    Mou, D.4    Wan, J.5    Zhang, J.6
  • 120
    • 84936797733 scopus 로고    scopus 로고
    • Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
    • 1:CAS:528:DC%2BC2MXhtVOhsbjP 26100900 4500284
    • Yu J, Zhang Y, Ye Y, DiSanto R, Sun W, Ranson D, et al. Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. Proc Natl Acad Sci U S A. 2015;112(27):8260-5.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.27 , pp. 8260-8265
    • Yu, J.1    Zhang, Y.2    Ye, Y.3    DiSanto, R.4    Sun, W.5    Ranson, D.6
  • 121
    • 84925307572 scopus 로고    scopus 로고
    • Drug coated microneedles for minimally-invasive treatment of oral carcinomas: Development and in vitroevaluation
    • Ma Y, Boese S, Luo Z, Nitin N, Gill H. Drug coated microneedles for minimally-invasive treatment of oral carcinomas: development and in vitroevaluation. Biomed Microdevices. 2015;17(2):1.
    • (2015) Biomed Microdevices , vol.17 , Issue.2 , pp. 1
    • Ma, Y.1    Boese, S.2    Luo, Z.3    Nitin, N.4    Gill, H.5
  • 122
    • 84903268746 scopus 로고    scopus 로고
    • Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles
    • 1:CAS:528:DC%2BC2cXhtFOrsbjM 24928134
    • Paleco R, Vučen SR, Crean AM, Moore A, Scalia S. Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles. Int J Pharm. 2014;472(1-2):206-13.
    • (2014) Int J Pharm , vol.472 , Issue.1-2 , pp. 206-213
    • Paleco, R.1    Vučen, S.R.2    Crean, A.M.3    Moore, A.4    Scalia, S.5
  • 123
    • 84883741603 scopus 로고    scopus 로고
    • Improved percutaneous delivery of ketoprofen using combined application of nanocarriers and silicon microneedles
    • 24028612
    • Vučen SR, Vuleta G, Crean AM, Moore AC, Ignjatović N, Uskoković D. Improved percutaneous delivery of ketoprofen using combined application of nanocarriers and silicon microneedles. J Pharm Pharmacol. 2013;65(10):1451-62.
    • (2013) J Pharm Pharmacol , vol.65 , Issue.10 , pp. 1451-1462
    • Vučen, S.R.1    Vuleta, G.2    Crean, A.M.3    Moore, A.C.4    Ignjatović, N.5    Uskoković, D.6
  • 124
    • 78649636402 scopus 로고    scopus 로고
    • Microneedle-mediated intradermal nanoparticle delivery: Potential for enhanced local administration of hydrophobic pre-formed photosensitisers
    • 1:CAS:528:DC%2BC3cXhsVygsbzM 21112544
    • Donnelly RF, Morrow DIJ, Fay F, Scott CJ, Abdelghany S, Singh RRT, et al. Microneedle-mediated intradermal nanoparticle delivery: potential for enhanced local administration of hydrophobic pre-formed photosensitisers. Photodiagnosis Photodyn Ther. 2010;7(4):222-31.
    • (2010) Photodiagnosis Photodyn Ther , vol.7 , Issue.4 , pp. 222-231
    • Donnelly, R.F.1    Morrow, D.I.J.2    Fay, F.3    Scott, C.J.4    Abdelghany, S.5    Singh, R.R.T.6
  • 125
    • 84867573854 scopus 로고    scopus 로고
    • Effect of microneedle treatment on the skin permeation of a nanoencapsulated dye
    • 1:CAS:528:DC%2BC38Xhs1ahtrjP 23058046 4119958
    • Gomaa YA, El-Khordagui LK, Garland MJ, Donnelly RF, McInnes F, Meidan VM. Effect of microneedle treatment on the skin permeation of a nanoencapsulated dye. J Pharm Pharmacol. 2012;64(11):1592-602.
    • (2012) J Pharm Pharmacol , vol.64 , Issue.11 , pp. 1592-1602
    • Gomaa, Y.A.1    El-Khordagui, L.K.2    Garland, M.J.3    Donnelly, R.F.4    McInnes, F.5    Meidan, V.M.6
  • 126
    • 84860360081 scopus 로고    scopus 로고
    • Multidrug release based on microneedle arrays filled with pH-responsive PLGA hollow microspheres
    • 1:CAS:528:DC%2BC38Xlt1ajs7Y%3D 22484044
    • Ke CJ, Lin YJ, Hu YC, Chiang WL, Chen KJ, Yang WC, et al. Multidrug release based on microneedle arrays filled with pH-responsive PLGA hollow microspheres. Biomaterials. 2012;33(20):5156-65.
    • (2012) Biomaterials , vol.33 , Issue.20 , pp. 5156-5165
    • Ke, C.J.1    Lin, Y.J.2    Hu, Y.C.3    Chiang, W.L.4    Chen, K.J.5    Yang, W.C.6
  • 127
    • 84891815132 scopus 로고    scopus 로고
    • Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
    • 24403833 3883594
    • Lee SG, Jeong JH, Lee KM, Jeong KH, Yang H, Kim M, et al. Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule. Int J Nanomedicine. 2014;9:289-99.
    • (2014) Int J Nanomedicine , vol.9 , pp. 289-299
    • Lee, S.G.1    Jeong, J.H.2    Lee, K.M.3    Jeong, K.H.4    Yang, H.5    Kim, M.6
  • 128
    • 84934912806 scopus 로고    scopus 로고
    • Biodegradable and conductive chitosan-graphene quantum dot nanocomposite microneedles for delivery of both small and large molecular weight therapeutics
    • 1:CAS:528:DC%2BC2MXpsF2murw%3D
    • Justin R, Román S, Chen D, Tao K, Geng X, Grant RT, et al. Biodegradable and conductive chitosan-graphene quantum dot nanocomposite microneedles for delivery of both small and large molecular weight therapeutics. RSC Adv. 2015;5(64):51934-46.
    • (2015) RSC Adv , vol.5 , Issue.64 , pp. 51934-51946
    • Justin, R.1    Román, S.2    Chen, D.3    Tao, K.4    Geng, X.5    Grant, R.T.6
  • 129
    • 84875674290 scopus 로고    scopus 로고
    • Skin dendritic cell targeting via microneedle arrays laden with antigen-encapsulated poly-D, L-lactide-co-glycolide nanoparticles induces efficient antitumor and antiviral immune responses
    • 1:CAS:528:DC%2BC3sXhvVymt7k%3D 23373658 3936823
    • Zaric M, Lyubomska O, Touzelet O, Poux C, Al-Zahrani S, Fay F, et al. Skin dendritic cell targeting via microneedle arrays laden with antigen-encapsulated poly-D, L-lactide-co-glycolide nanoparticles induces efficient antitumor and antiviral immune responses. ACS Nano. 2013;7(3):2042-55.
    • (2013) ACS Nano , vol.7 , Issue.3 , pp. 2042-2055
    • Zaric, M.1    Lyubomska, O.2    Touzelet, O.3    Poux, C.4    Al-Zahrani, S.5    Fay, F.6
  • 130
    • 9344271546 scopus 로고    scopus 로고
    • Immunity in response to particulate antigen-delivery systems
    • 1:CAS:528:DC%2BD2cXhtVSntb3F 15560945
    • Storni T, Kündig TM, Senti G, Johansen P. Immunity in response to particulate antigen-delivery systems. Adv Drug Deliv Rev. 2005;57(3):333-55.
    • (2005) Adv Drug Deliv Rev , vol.57 , Issue.3 , pp. 333-355
    • Storni, T.1    Kündig, T.M.2    Senti, G.3    Johansen, P.4
  • 131
    • 0037159628 scopus 로고    scopus 로고
    • Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres
    • 1:CAS:528:DC%2BD38XoslCgsrk%3D 12443664
    • Gutierro I, Hernandez RM, Igartua M, Gascon AR, Pedraz JL. Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres. Vaccine. 2002;21(1-2):67-77.
    • (2002) Vaccine , vol.21 , Issue.1-2 , pp. 67-77
    • Gutierro, I.1    Hernandez, R.M.2    Igartua, M.3    Gascon, A.R.4    Pedraz, J.L.5
  • 132
    • 33646139149 scopus 로고    scopus 로고
    • Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant Hepatitis B antigen administered intranasally
    • 1:CAS:528:DC%2BD28XksFejs7w%3D 16446012
    • Jaganathan KS, Vyas SP. Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant Hepatitis B antigen administered intranasally. Vaccine. 2006;24(19):4201-11.
    • (2006) Vaccine , vol.24 , Issue.19 , pp. 4201-4211
    • Jaganathan, K.S.1    Vyas, S.P.2
  • 133
    • 82155187080 scopus 로고    scopus 로고
    • Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines
    • 1:CAS:528:DC%2BC38Xms1Crug%3D%3D
    • Mahapatro A, Singh DK. Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines. J Nanobiotechnol. 2011;9(1):55.
    • (2011) J Nanobiotechnol , vol.9 , Issue.1 , pp. 55
    • Mahapatro, A.1    Singh, D.K.2
  • 134
    • 84859129512 scopus 로고    scopus 로고
    • Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection
    • 22303914
    • De Geest BG, Willart MA, Hammad H, Lambrecht BN, Pollard C, Bogaert P, et al. Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection. ACS Nano. 2012;6(3):2136-49.
    • (2012) ACS Nano , vol.6 , Issue.3 , pp. 2136-2149
    • De Geest, B.G.1    Willart, M.A.2    Hammad, H.3    Lambrecht, B.N.4    Pollard, C.5    Bogaert, P.6
  • 135
    • 79955647601 scopus 로고    scopus 로고
    • Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation
    • 1:CAS:528:DC%2BC3MXmtFamtL8%3D 21443959
    • Bal SM, Slütter B, Jiskoot W, Bouwstra JA. Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation. Vaccine. 2011;29(23):4025-32.
    • (2011) Vaccine , vol.29 , Issue.23 , pp. 4025-4032
    • Bal, S.M.1    Slütter, B.2    Jiskoot, W.3    Bouwstra, J.A.4
  • 136
    • 80155188417 scopus 로고    scopus 로고
    • Permeation of antigen protein-conjugated nanoparticles and live bacteria through microneedle-treated mouse skin
    • 1:CAS:528:DC%2BC3MXotF2ntLo%3D 21753877 3131192
    • Kumar A, Li XR, Sandoval MA, Rodriguez BL, Sloat BR, Cui ZR. Permeation of antigen protein-conjugated nanoparticles and live bacteria through microneedle-treated mouse skin. Int J Nanomedicine. 2011;6:1253-64.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1253-1264
    • Kumar, A.1    Li, X.R.2    Sandoval, M.A.3    Rodriguez, B.L.4    Sloat, B.R.5    Cui, Z.R.6
  • 137
    • 84866662937 scopus 로고    scopus 로고
    • Microneedle-mediated transcutaneous immunization with plasmid DNA coated on cationic PLGA nanoparticles
    • 1:CAS:528:DC%2BC38XhsFans7zI 22921518 3478475
    • Kumar A, Wonganan P, Sandoval MA, Li X, Zhu S, Cui Z. Microneedle-mediated transcutaneous immunization with plasmid DNA coated on cationic PLGA nanoparticles. J Control Release. 2012;163(2):230-9.
    • (2012) J Control Release , vol.163 , Issue.2 , pp. 230-239
    • Kumar, A.1    Wonganan, P.2    Sandoval, M.A.3    Li, X.4    Zhu, S.5    Cui, Z.6
  • 139
    • 84904340550 scopus 로고    scopus 로고
    • Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery
    • 1:CAS:528:DC%2BC2cXht1KksbjF 24995949
    • McCarthy HO, McCaffrey J, McCrudden CM, Zholobenko A, Ali AA, McBride JW, et al. Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery. J Control Release. 2014;189(1):141-9.
    • (2014) J Control Release , vol.189 , Issue.1 , pp. 141-149
    • McCarthy, H.O.1    McCaffrey, J.2    McCrudden, C.M.3    Zholobenko, A.4    Ali, A.A.5    McBride, J.W.6
  • 141
    • 84872082784 scopus 로고    scopus 로고
    • Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination
    • 1:CAS:528:DC%2BC38Xht1Glu77M 23503923 3595545
    • DeMuth PC, Garcia-Beltran WF, Ai-Ling ML, Hammond PT, Irvine DJ. Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination. Adv Funct Mater. 2013;23(2):161-72.
    • (2013) Adv Funct Mater , vol.23 , Issue.2 , pp. 161-172
    • DeMuth, P.C.1    Garcia-Beltran, W.F.2    Ai-Ling, M.L.3    Hammond, P.T.4    Irvine, D.J.5
  • 142
    • 84925378659 scopus 로고    scopus 로고
    • Dissolving microneedle delivery of nanoparticle-encapsulated antigen elicits efficient cross-priming and Th1 immune responses by murine langerhans cells
    • 1:CAS:528:DC%2BC2cXhsl2gsbfE 25243789
    • Zaric M, Lyubomska O, Poux C, Hanna ML, McCrudden MT, Malissen B, et al. Dissolving microneedle delivery of nanoparticle-encapsulated antigen elicits efficient cross-priming and Th1 immune responses by murine langerhans cells. J Invest Dermatol. 2015;135(2):425-34.
    • (2015) J Invest Dermatol , vol.135 , Issue.2 , pp. 425-434
    • Zaric, M.1    Lyubomska, O.2    Poux, C.3    Hanna, M.L.4    McCrudden, M.T.5    Malissen, B.6
  • 143
    • 84893903503 scopus 로고    scopus 로고
    • Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine
    • 1:CAS:528:DC%2BC2cXksF2ntrs%3D 24462900
    • Kim NW, Lee MS, Kim KR, Lee JE, Lee K, Park JS, et al. Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine. J Control Release. 2014;179:11-7.
    • (2014) J Control Release , vol.179 , pp. 11-17
    • Kim, N.W.1    Lee, M.S.2    Kim, K.R.3    Lee, J.E.4    Lee, K.5    Park, J.S.6
  • 144
    • 84918587529 scopus 로고    scopus 로고
    • Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization
    • 1:CAS:528:DC%2BC2cXhvV2mtLjN
    • Hu Y, Xu B, Xu J, Shou D, Liu E, Gao J, et al. Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization. Polym Chem. 2015;6(3):373-9.
    • (2015) Polym Chem , vol.6 , Issue.3 , pp. 373-379
    • Hu, Y.1    Xu, B.2    Xu, J.3    Shou, D.4    Liu, E.5    Gao, J.6
  • 145
    • 70349244943 scopus 로고    scopus 로고
    • Enhanced detection of early-stage oral cancer in vivo by optical coherence tomography using multimodal delivery of gold nanoparticles
    • 19566301 2872553
    • Kim CS, Wilder-Smith P, Ahn YC, Liaw LHL, Chen Z, Kwon YJ. Enhanced detection of early-stage oral cancer in vivo by optical coherence tomography using multimodal delivery of gold nanoparticles. J Biomed Opt. 2009;14(3):034008.
    • (2009) J Biomed Opt , vol.14 , Issue.3
    • Kim, C.S.1    Wilder-Smith, P.2    Ahn, Y.C.3    Liaw, L.H.L.4    Chen, Z.5    Kwon, Y.J.6
  • 146
    • 84864684457 scopus 로고    scopus 로고
    • Efficient and facile delivery of gold nanoparticles in vivo using dissolvable microneedles for contrast-enhanced optical coherence tomography
    • 1:CAS:528:DC%2BC3MXitlSnurY%3D 21258450 3005167
    • Kim CS, Ahn YC, Wilder-Smith P, Oh S, Chen Z, Kwon YJ. Efficient and facile delivery of gold nanoparticles in vivo using dissolvable microneedles for contrast-enhanced optical coherence tomography. Biomed Opt Express. 2010;1(1):106-13.
    • (2010) Biomed Opt Express , vol.1 , Issue.1 , pp. 106-113
    • Kim, C.S.1    Ahn, Y.C.2    Wilder-Smith, P.3    Oh, S.4    Chen, Z.5    Kwon, Y.J.6
  • 147
    • 78651288385 scopus 로고    scopus 로고
    • Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles
    • 1:CAS:528:DC%2BC3MXhs1Wjsg%3D%3D 21413181 3060378
    • Gittard SD, Miller PR, Boehm RD, Ovsianikov A, Chichkov BN, Heiser J, et al. Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles. Faraday Discuss. 2011;149(1):171-85.
    • (2011) Faraday Discuss , vol.149 , Issue.1 , pp. 171-185
    • Gittard, S.D.1    Miller, P.R.2    Boehm, R.D.3    Ovsianikov, A.4    Chichkov, B.N.5    Heiser, J.6
  • 148
    • 77949877695 scopus 로고    scopus 로고
    • Fabrication of microneedles using two photon polymerization for transdermal delivery of nanomaterials
    • 1:CAS:528:DC%2BC3cXhsVWgsbvE 21137723
    • Doraiswamy A, Ovsianikov A, Gittard SD, Monteiro-Riviere NA, Crombez R, Montalvo E, et al. Fabrication of microneedles using two photon polymerization for transdermal delivery of nanomaterials. J Nanosci Nanotechnol. 2010;10(10):6305-12.
    • (2010) J Nanosci Nanotechnol , vol.10 , Issue.10 , pp. 6305-6312
    • Doraiswamy, A.1    Ovsianikov, A.2    Gittard, S.D.3    Monteiro-Riviere, N.A.4    Crombez, R.5    Montalvo, E.6
  • 149
    • 84887411650 scopus 로고    scopus 로고
    • Transdermal delivery devices: Fabrication, mechanics and drug release from silk
    • 1:CAS:528:DC%2BC3sXnt1Sjurs%3D 23653252 3883884
    • Raja WK, Maccorkle S, Diwan IM, Abdurrob A, Lu J, Omenetto FG, et al. Transdermal delivery devices: fabrication, mechanics and drug release from silk. Small. 2013;9(21):3704-13.
    • (2013) Small , vol.9 , Issue.21 , pp. 3704-3713
    • Raja, W.K.1    Maccorkle, S.2    Diwan, I.M.3    Abdurrob, A.4    Lu, J.5    Omenetto, F.G.6
  • 150
    • 84898628176 scopus 로고    scopus 로고
    • Nanocomposite-strengthened dissolving microneedles for improved transdermal delivery to human skin
    • 1:CAS:528:DC%2BC2cXmtVelu74%3D 24173960
    • Yan L, Raphael AP, Zhu X, Wang B, Chen W, Tang T, et al. Nanocomposite-strengthened dissolving microneedles for improved transdermal delivery to human skin. Adv Healthc Mater. 2014;3(4):555-64.
    • (2014) Adv Healthc Mater , vol.3 , Issue.4 , pp. 555-564
    • Yan, L.1    Raphael, A.P.2    Zhu, X.3    Wang, B.4    Chen, W.5    Tang, T.6
  • 151
    • 80055120196 scopus 로고    scopus 로고
    • Hydrogel swelling as a trigger to release biodegradable polymer microneedles in skin
    • 1:CAS:528:DC%2BC3MXhsVWkt7nJ 22000788
    • Kim M, Jung B, Park JH. Hydrogel swelling as a trigger to release biodegradable polymer microneedles in skin. Biomaterials. 2012;33(2):668-78.
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 668-678
    • Kim, M.1    Jung, B.2    Park, J.H.3
  • 152
    • 84929174271 scopus 로고    scopus 로고
    • Near-infrared light-responsive composite microneedles for on-demand transdermal drug delivery
    • 1:CAS:528:DC%2BC2MXlslKgt70%3D 25839774
    • Chen MC, Ling MH, Wang KW, Lin ZW, Lai BH, Chen DH. Near-infrared light-responsive composite microneedles for on-demand transdermal drug delivery. Biomacromolecules. 2015;16(5):1598-607.
    • (2015) Biomacromolecules , vol.16 , Issue.5 , pp. 1598-1607
    • Chen, M.C.1    Ling, M.H.2    Wang, K.W.3    Lin, Z.W.4    Lai, B.H.5    Chen, D.H.6
  • 153
    • 84920669167 scopus 로고    scopus 로고
    • Remotely triggered release of small molecules from LaB6@SiO2-loaded polycaprolactone microneedles
    • 1:CAS:528:DC%2BC2cXitV2gu7rL 25463507
    • Chen MC, Wang KW, Chen DH, Ling MH, Liu CY. Remotely triggered release of small molecules from LaB6@SiO2-loaded polycaprolactone microneedles. Acta Biomater. 2015;13:344-53.
    • (2015) Acta Biomater , vol.13 , pp. 344-353
    • Chen, M.C.1    Wang, K.W.2    Chen, D.H.3    Ling, M.H.4    Liu, C.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.