Sustained-release self-dissolving micropiles for percutaneous absorption of insulin in mice

Journal of Drug Targeting

Volumn 15, Issue 5, 2007, Pages 323-326

  Ito, Yukako ^a   Hagiwara, Eiji ^a   Saeki, Atsushi ^a   Sugioka, Nobuyuki ^a   Takada, Kanji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Chondroitin sulfate; Insulin; Long acting; Micropiles; Porous calcium silicate; Porous silicon dioxide

Indexed keywords

CALCIUM SILICATE; CHONDROITIN SULFATE; FLORITE RE; GLUCOSE; HUMAN INSULIN; INSULIN ZINC SUSPENSION; PENFIL N; PLACEBO; SILICON DIOXIDE; SYLYSIA 320; SYLYSIA 440; SYLYSIA 730; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ADSORPTION; DRUG SOLUBILITY; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SUSTAINED RELEASE FORMULATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; BLOOD GLUCOSE; CALCIUM COMPOUNDS; CHONDROITIN SULFATES; DELAYED-ACTION PREPARATIONS; DRUG EVALUATION, PRECLINICAL; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN, LONG-ACTING; MALE; METABOLIC CLEARANCE RATE; MICE; MICROSPHERES; PARTICLE SIZE; POROSITY; SILICATES; SILICON DIOXIDE; SKIN ABSORPTION; SOLUBILITY; TIME FACTORS;

EID: 34250011186     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860701349794     Document Type: Article

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