Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Volumn 5, Issue 3, 2013, Pages 205-218

  Zhang, Zheng ^a   Tsai, Pei Chin ^b,c   Ramezanli, Tannaz ^b,c   Michniak Kohn, Bozena B ^a,b,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERMATOLOGICAL DISEASE; NANO-SIZED DRUG CARRIERS; PERMEATION BARRIERS; PERMEATION ENHANCEMENT; SPECIAL APPLICATIONS; SUBCUTANEOUS TISSUES; SYSTEMIC CIRCULATION; TRANSDERMAL DELIVERY;

AMINO ACIDS; DERMATOLOGY; NANOPARTICLES; NANOSPHERES; SKIN; STEM CELLS; TISSUE;

DISEASES;

ACICLOVIR; ALUMINUM ACETATE; ANTIHISTAMINIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CALAMINE; CLOBETASOL PROPIONATE; COLECALCIFEROL; CORTICOSTEROID; DITHRANOL; ESTRADIOL; FLUOROURACIL; HYDROCORTISONE; IMIQUIMOD; IPILIMUMAB; NANOPARTICLE; OXYBENZONE; PACLITAXEL; PILOCARPINE; PLASMID DNA; POLYMER; QUERCETIN; RETINOL; TOPICAL AGENT; VEMURAFENIB; ZINC OXIDE;

BASAL CELL CARCINOMA; BREAST CANCER; CANCER SURGERY; CONTACT DERMATITIS; CORTICOSTEROID THERAPY; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG PENETRATION; HAIR FOLLICLE; HUMAN; MELANOMA; MICRONEEDLE; MULTIMODALITY CANCER THERAPY; NANOENCAPSULATION; PARTICLE SIZE; PARTITION COEFFICIENT; PATHOGENESIS; PERMEABILITY BARRIER; PHOTOTHERAPY; PRIORITY JOURNAL; PSORIASIS; REVIEW; SIDE EFFECT; SKIN CANCER; SKIN DISEASE; SKIN IRRITATION; SKIN PENETRATION; SQUAMOUS CELL CARCINOMA; STEM CELL; STRATUM CORNEUM; SYSTEMIC THERAPY; TOPICAL TREATMENT; TRANSDERMAL DRUG ADMINISTRATION; VASODILATATION;

ADMINISTRATION, TOPICAL; ANIMALS; DRUG DELIVERY SYSTEMS; HUMANS; NANOPARTICLES; POLYMERS; SKIN; SKIN DISEASES;

EID: 84876484450     PISSN: 19395116     EISSN: 19390041     Source Type: Journal    
DOI: 10.1002/wnan.1211     Document Type: Review

References (69)

1. Holbrook KA, Wolff K. The structure and development of skin. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF, eds. Dermatology in General Medicine. New York, NY: McGraw-Hill; 1987, 93-131.
2. Scheuplein RJ, Blank IH. Permeability of the skin. Physiol Rev 1971, 51:702-747.
3. Cotsarelis G. Epithelial stem cells: a folliculocentric view. J Invest Dermatol. 2006, 126:1459-1468.
4. Paudel KS, Milewski M, Swadley CL, Brogden NK, Ghosh P, Stinchcomb AL. Challenges and opportunities in dermal/transdermal delivery. Ther Deliv 2010, 1:109-131.
5. Hadgraft J, Guy RH. Feasibility assessment in topical and transdermal delivery: mathematical models and in vitro studies. In: Guy RH, Hadgraft J, eds. Transdermal Drug Delivery. 2nd ed. New York, NY: Marcel Dekker, Inc.; 2003, 1-23.
6. Higuchi T. Physical chemical analysis of percutaneous absorption process from creams and ointments. J Soc Cosmet Chem 1960, 11:85-97.
7. Alvarez-Roman R, Naik A, Kalia YN, Guy RH, Fessi H. Skin penetration and distribution of polymeric nanoparticles. J Control Release 2004, 99:53-62.
8. Zhang Q, Grice JE, Li P, Jepps OG, Wang GJ, Roberts MS. Skin solubility determines maximum transepidermal flux for similar size molecules. Pharm Res 2009, 26:1974-1985.
9. Moser K, Kriwet K, Naik A, Kalia YN, Guy RH. Passive skin penetration enhancement and its quantification in vitro. Eur J Pharm Biopharm 2001, 52:103-112.
10. Barry BW. Penetration enhancer classification. In: Smith EW, Maibach HI, eds. Percutaneous Penetration Enhancers. 2nd ed. New York, NY: Taylor and Francis; 2006, 3-16.
11. Alvarez-Roman R, Naik A, Kalia YN, Guy RH, Fessi H. Enhancement of topical delivery from biodegradable nanoparticles. Pharm Res 2004, 21:1818-1825.
12. Cormier M, Johnson B, Ameri M, Nyam K, Libiran L, Zhang DD, Daddona P. Transdermal delivery of desmopressin using a coated microneedle array patch system. J Control Release 2004, 97:503-511.
13. Akomeah FK, Martin GP, Muddle AG, Brown MB. Effect of abrasion induced by a rotating brush on the skin permeation of solutes with varying physicochemical properties. Eur J Pharm Biopharm 2008, 68:724-734.
14. Alvarez-Roman R, Merino G, Kalia YN, Naik A, Guy RH. Skin permeability enhancement by low frequency sonophoresis: lipid extraction and transport pathways. J Pharm Sci 2003, 92:1138-1146.
15. Mori K, Hasegawa T, Sato S, Sugibayashi K. Effect of electric field on the enhanced skin permeation of drugs by electroporation. J Control Release 2003, 90:171-179.
16. Harvey AJ, Kaestner SA, Sutter DE, Harvey NG, Mikszta JA, Pettis RJ. Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs. Pharm Res 2011, 28:107-116.
17. Fukushima K, Ise A, Morita H, Hasegawa R, Ito Y, Sugioka N, Takada K. Two-layered dissolving microneedles for percutaneous delivery of peptide/protein drugs in rats. Pharm Res 2011, 28:7-21.
18. Coulman SA, Barrow D, Anstey A, Gateley C, Morrissey A, Wilke N, Allender C, Brain K, Birchall JC. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Curr Drug Deliv 2006, 3:65-75.
19. Quan FS, Kim YC, Compans RW, Prausnitz MR, Kang SM. Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles. J Control Release 2010, 147:326-332.
20. Bowcock AM, Krueger JG. Getting under the skin: the immunogenetics of psoriasis. Nat Rev Immunol 2005, 5:699-711.
21. Clark RA, Kupper TS. Misbehaving macrophages in the pathogenesis of psoriasis. J Clin Invest 2006, 116:2084-2087.
22. Danilenko DM. Review paper: preclinical models of psoriasis. Vet Pathol 2008, 45:563-575.
23. Van de Kerkhof PC, Vissers WH. Established treatments of psoriasis. Curr Drug Targets Inflamm Allergy 2004, 3:145-156.
24. Naldi L, Griffiths CE. Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks. Br J Dermatol 2005, 152:597-615.
25. Andersen KE, Benezra C, Burrows D, Camarasa J, Dooms-Goossens A, Ducombs G, Frosch P, Lachapelle JM, Lahti A, Menné T, et al. Contact dermatitis. A review. Contact Dermatitis 1987, 16:55-78.
26. Nosbaum A, Vocanson M, Rozieres A, Hennino A, Nicolas JF. Allergic and irritant contact dermatitis. Eur J Dermatol 2009, 19:325-332.
27. Plake KS, Darbishire PL. Contact dermatitis. In: Krinsky DL, Berardi RR, Ferreri SP, Hume AL, Newton GD, Rollins CJ, Tietze KJ, eds. APhA Handbook of Nonprescription Drugs, an Interactive Approach to Self-Care. Washington, DC: American Pharmacists Association; 2012, 645-660, Chapter 34.
28. Narayanan DL, Saladi RN, Fox JL. Ultraviolet radiation and skin cancer. Int J Dermatol 2010, 49:978-986.
29. Bendesky A, Michel A, Sordo M, Calderon-Aranda ES, Acosta-Saavedra LC, Salazar AM, Podoswa N, Ostrosky-Wegman P. DNA damage, oxidative mutagen sensitivity, and repair of oxidative DNA damage in nonmelanoma skin cancer patients. Environ Mol Mutagen 2006, 47:509-517.
30. Kanjilal S, Strom SS, Clayman GL, Weber RS, El-Naggar AK, Kapur V, Cummings KK, Hill LA, Spitz MR, Kripke ML, et al. p53 mutations in nonmelanoma skin cancer of the head and neck: molecular evidence for field cancerization. Cancer Res 1995, 55:3604-3609.
31. Ro YS. Oncogene interaction in basal cell carcinomas of human skin. J Korean Med Sci 1995, 10:85-92.
32. Dréau D, Culberson C, Wyatt S, Holder WD. Human papilloma virus in melanoma biopsy specimens and its relation to melanoma progression. Ann Surg 2000, 231:664-671.
33. Williams AC. Topical 5-FU-a new approach to skin cancer. Ann Surg 1971, 173:864-871.
34. Urosevic M, Dummer R. Role of imiquimod in skin cancer treatment. Am J Clin Dermatol 2004, 5:453-458.
35. Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003, 3:330-338.
36. Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs. Cancer Res 1986, 46:6387-6392.
37. Guterres SS, Alves MP, Pohlmann AR. Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications. Drug Target Insights 2007, 2:147-157.
38. Lee RW, Shenoy DB, Sheel R. Micellar nanoparticles: applications for topical and passive transdermal drug delivery. In: Kulkarni VS, ed. Handbook of Non-Invasive Drug Delivery Systems. Burlington, MA: Elsevier Inc.; 2010, 37-58, Chapter 2.
39. Vandervoort J, Ludwig A. Preparation and evaluation of drug-loaded gelatin nanoparticles for topical ophthalmic use. Eur J Pharm Biopharm 2004, 57:251-261.
40. Patel M, Jain SK, Yadav AK, Gogna D, Agrawal GP. Preparation and characterization of oxybenzone-loaded gelatin microspheres for enhancement of sunscreening efficacy. Drug Deliv 2006, 13:323-330.
41. Kim DG, Jeong YI, Choi C, Roh SH, Kang SK, Jang MK, Nah JW. Retinol-encapsulated low molecular water-soluble chitosan nanoparticles. Int J Pharm 2006, 319:130-138.
42. Ozbas-Turan S, Akbuga J, Sezer AD. Topical application of antisense oligonucleotide-loaded chitosan nanoparticles to rats. Oligonucleotides 2010, 20: 147-153.
43. Hasanovic A, Zehl M, Reznicek G, Valenta C. Chitosan-tripolyphosphate nanoparticles as a possible skin drug delivery system for aciclovir with enhanced stability. J Pharm Pharmacol 2009, 61:1609-1616.
44. Ozbas-Turan S, Akbuga J. Plasmid DNA-loaded chitosan/TPP nanoparticles for topical gene delivery. Drug Deliv 2011, 18:215-222.
45. Şenyiǧit T, Sonvico F, Barbieri S, Ozer O, Santi P, Colombo P. Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin. J Control Release 2010, 142:368-373.
46. Tan Q, Liu W, Guo C, Zhai G. Preparation and evaluation of quercetin-loaded lecithin-chitosan nanoparticles for topical delivery. Int J Nanomed 2011, 6:1621-1630.
47. Shahnaz G, Vetter A, Barthelmes J, Rahmat D, Laffleur F, Iqbal J, Perera G, Schlocker W, Dunnhaput S, Augustijns P, et al. Thiolated chitosan nanoparticles for the nasal administration of leuprolide: bioavailability and pharmacokinetic characterization. Int J Pharm 2012, 428:164-170.
48. de la Fuente M, Seijo B, Alonso MJ. Bioadhesive hyaluronan-chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue. Gene Ther 2008, 15:668-676.
49. Chuah LH, Billa N, Roberts CJ, Burley JC, Manickam S. Curcumin-containing chitosan nanoparticles as a potential mucoadhesive delivery system to the colon. Pharm Dev Technol 2011, 1-9. doi: 10.3109/10837450.2011.640688.
50. Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 2003, 55:329-347.
51. Tsujimoto H, Hara K, Tsukada Y, Huang CC, Kawashima Y, Arakaki M, Okayasu H, Mimura H, Miwa N. Evaluation of the permeability of hairgrowing ingredient encapsulated PLGA nanospheres to hair follicles and their hairgrowing effects. Bioorg Med Chem Lett 2007, 17:4771-4777.
52. Tomoda K, Terashima H, Suzuki K, Inagi T, Terada H, Makino K. Enhanced transdermal delivery of indomethacin-loaded PLGA nanoparticles by iontophoresis. Colloids Surf B Biointerfaces 2011, 88:706-710.
53. Shah PP, Desai PR, Patel AR, Singh MS. Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs. Biomaterials 2012, 33:1607-1617.
54. Alvarez-Roman R, Barre G, Guy RH, Fessi H. Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection. Eur J Pharm Biopharm 2001, 52:191-195.
55. Shim J, Seok Kang H, Park WS, Han SH, Kim J, Chang IS. Transdermal delivery of mixnoxidil with block copolymer nanoparticles. J Control Release 2004, 97:477-484.
56. Wu X, Price GJ, Guy RH. Disposition of nanoparticles and an associated lipophilic permeant following topical application to the skin. Mol Pharm 2009, 6:1441-1448.
57. Turos E, Shim JY, Wang Y, Greenhalgh K, Suresh Kumar Reddy GS, Dickey S, Lim DV. Antibiotic-conjugated polyacrylate nanoparticles: new opportunities for development of anti-MRSA agents. Bioorg Med Chem Lett 2007, 17:53-56.
58. Greenhalgh K, Turos E. In vivo studies of polyacrylate nanoparticle emulsions for topical and systemic applications. Nanomedicine 2009, 5:46-54.
59. Sheihet L, Piotrowska K, Dubin RA, Kohn J, Devore D. Effect of tyrosine-derived triblock copolymer compositions on nanosphere self-assembly and drug delivery. Biomacromolecules 2007, 8:998-1003.
60. Kilfoyle BE, Sheihet L, Zhang Z, Laohoo M, Kohn J, Michniak-Kohn BB. Development of paclitaxel-TyroSpheres for topical skin treatment. J Control Release 2012, 163:18-24. doi: 10.1016/j.jconrel.2012.06.021.
61. Sheihet L, Garbuzenko OB, Bushman J, Gounder MK, Minko T, Kohn J. Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: in vivo evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor. Eur J Pharm Sci 2012, 45:320-329.
62. Batheja P, Sheihet L, Kohn J, Singer AJ, Michniak-Kohn B. Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo skin distribution studies. J Control Release 2011, 149:159-167.
63. Sheihet L, Chandra P, Batheja P, Devore D, Kohn J, Michniak B. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int J Pharm 2008, 350:312-319.
64. Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A 2009, 106:19268-19273.
65. Choi HS, Ashitate Y, Lee JH, Kim SH, Matsui A, Insin N, Bawendi MG, Semmler-Behnke M, Frangioni JV, Tsuda A. Rapid translocation of nanoparticles from the lung airspaces to the body. Nat Biotechnol 2010, 28:1300-1303.
66. Zheng D, Giljohann DA, Chen DL, Massich MD, Wang XQ, Iordanov H, Mirkin CA, Paller AS. Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation. Proc Natl Acad Sci U S A 2012, 109:11975-11980.
67. Zhang W, Gao J, Zhu Q, Zhang M, Ding X, Wang X, Hou X, Fan W, Ding B, Wu X, et al. Penetration and distribution of PLGA nanoparticles in the human skin treated with microneedles. Int J Pharm 2010, 402:205-212.
68. Coulman SA, Anstey A, Gateley C, Morrissey A, McLoughlin P, Allender C, Birchall JC. Microneedle mediated delivery of nanoparticles into human skin. Int J Pharm 2009, 366:190-200.
69. del Pilar Martin M, Weldon WC, Zarnitsyn VG, Koutsonanos DG, Akbari H, Skountzou I, Jacob J, Prausnitz MR, Compans RW. Local response to microneedle-based influenza immunization in the skin. MBio 2012, 3. doi: 10.1128/mBio.00012-12.