Microneedle/nanoencapsulation-mediated transdermal delivery: Mechanistic insights

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 86, Issue 2, 2014, Pages 145-155

  Gomaa, Yasmine A ^a,c   Garland, Martin J ^b   McInnes, Fiona J ^a,d   Donnelly, Ryan F ^b   El Khordagui, Labiba K ^c   Wilson, Clive G ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c Alexandria University Faculty of Pharmacy   (Egypt)

^d GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

Confocal laser scanning microscopy; Fluorescein isothicoyanate; Microneedles; PLGA nanoparticles; Rhodamine B; Skin permeation; Transdermal delivery

Indexed keywords

DYE; FLUORESCEIN ISOTHIOCYANATE; NANOPARTICLE; POLYGLACTIN; RHODAMINE B;

ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; MICRONEEDLE; MOLECULAR WEIGHT; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; SKIN; SKIN PERMEABILITY; ZETA POTENTIAL;

CONFOCAL LASER SCANNING MICROSCOPY; FLUORESCEIN ISOTHICOYANATE; MICRONEEDLES; PLGA NANOPARTICLES; RHODAMINE B; SKIN PERMEATION; TRANSDERMAL DELIVERY;

ADMINISTRATION, CUTANEOUS; ANIMALS; DRUG DELIVERY SYSTEMS; FLUORESCEIN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOTHIOCYANATES; LACTIC ACID; MICROINJECTIONS; NANOPARTICLES; NEEDLES; PARTICLE SIZE; PERMEABILITY; POLYMERS; RHODAMINES; SKIN; SKIN ABSORPTION; SOLUBILITY; SWINE;

EID: 84896396738     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.01.026     Document Type: Article

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