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Volumn 33, Issue 5, 2012, Pages 1607-1617

Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs

Author keywords

Allergic contact dermatitis; Imiquimod; Psoriasis; Skin delivery; Skin permeating nanogel; Surface modified PLGA chitosan nanoparticles

Indexed keywords

ANTI-INFLAMMATORY DRUGS; CARBOPOL; CONTACT DERMATITIS; DRUG DELIVERY SYSTEM; DRUG RELEASE; GELLING AGENTS; IMIQUIMOD; IN-VITRO; INFLAMMATORY DISORDERS; KETOPROFEN; LACTIDES; METHYL CELLULOSE; NANOGELS; PSORIASIS; SKIN DELIVERY; SKIN LAYER; STABILITY STUDY; SURFACE-MODIFIED; TOPICAL DELIVERY; UNIFORM DISPERSIONS;

EID: 83355166267     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.11.011     Document Type: Article
Times cited : (184)

References (48)
  • 1
    • 70649114473 scopus 로고    scopus 로고
    • Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain
    • Wang Z.H., Wang Z.Y., Sun C.S., Wang C.Y., Jiang T.Y., Wang S.L. Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain. Biomaterials 2010, 31:908-915.
    • (2010) Biomaterials , vol.31 , pp. 908-915
    • Wang, Z.H.1    Wang, Z.Y.2    Sun, C.S.3    Wang, C.Y.4    Jiang, T.Y.5    Wang, S.L.6
  • 2
    • 80052762003 scopus 로고    scopus 로고
    • Nanotechnology in ocular delivery: current and future directions
    • Sultana Y., Maurya D.P., Iqbal Z., Aqil M. Nanotechnology in ocular delivery: current and future directions. Drugs Today (Barc) 2011, 47:441-455.
    • (2011) Drugs Today (Barc) , vol.47 , pp. 441-455
    • Sultana, Y.1    Maurya, D.P.2    Iqbal, Z.3    Aqil, M.4
  • 3
    • 77952670687 scopus 로고    scopus 로고
    • Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers
    • Patlolla R.R., Chougule M., Patel A.R., Jackson T., Tata P.N., Singh M. Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers. J Control Release 2010, 144:233-241.
    • (2010) J Control Release , vol.144 , pp. 233-241
    • Patlolla, R.R.1    Chougule, M.2    Patel, A.R.3    Jackson, T.4    Tata, P.N.5    Singh, M.6
  • 4
    • 0037027876 scopus 로고    scopus 로고
    • Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo
    • Pan Y., Li Y.J., Zhao H.Y., Zheng J.M., Xu H., Wei G., et al. Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm 2002, 249:139-147.
    • (2002) Int J Pharm , vol.249 , pp. 139-147
    • Pan, Y.1    Li, Y.J.2    Zhao, H.Y.3    Zheng, J.M.4    Xu, H.5    Wei, G.6
  • 5
    • 77955653919 scopus 로고    scopus 로고
    • Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen
    • Slutter B., Bal S., Keijzer C., Mallants R., Hagenaars N., Que I., et al. Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen. Vaccine 2010, 28:6282-6291.
    • (2010) Vaccine , vol.28 , pp. 6282-6291
    • Slutter, B.1    Bal, S.2    Keijzer, C.3    Mallants, R.4    Hagenaars, N.5    Que, I.6
  • 6
    • 74449084205 scopus 로고    scopus 로고
    • Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal langerhans cells tracking
    • Lee P.W., Hsu S.H., Tsai J.S., Chen F.R., Huang P.J., Ke C.J., et al. Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal langerhans cells tracking. Biomaterials 2010, 31:2425-2434.
    • (2010) Biomaterials , vol.31 , pp. 2425-2434
    • Lee, P.W.1    Hsu, S.H.2    Tsai, J.S.3    Chen, F.R.4    Huang, P.J.5    Ke, C.J.6
  • 7
    • 0034902043 scopus 로고    scopus 로고
    • Novel mechanisms and devices to enable successful transdermal drug delivery
    • Barry B.W. Novel mechanisms and devices to enable successful transdermal drug delivery. Eur J Pharm Sci 2001, 14:101-114.
    • (2001) Eur J Pharm Sci , vol.14 , pp. 101-114
    • Barry, B.W.1
  • 8
    • 80052270215 scopus 로고    scopus 로고
    • In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin
    • Jensen L.B., Petersson K., Nielsen H.M. In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin. Eur J Pharm Biopharm 2011, 79:68-75.
    • (2011) Eur J Pharm Biopharm , vol.79 , pp. 68-75
    • Jensen, L.B.1    Petersson, K.2    Nielsen, H.M.3
  • 9
    • 1642498299 scopus 로고    scopus 로고
    • Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II
    • Babu R.J., Kikwai L., Jaiani L.T., Kanikkannan N., Armstrong C.A., Ansel J.C., et al. Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II. Pharm Res 2004, 21:108-113.
    • (2004) Pharm Res , vol.21 , pp. 108-113
    • Babu, R.J.1    Kikwai, L.2    Jaiani, L.T.3    Kanikkannan, N.4    Armstrong, C.A.5    Ansel, J.C.6
  • 10
    • 1042269561 scopus 로고    scopus 로고
    • Preformulation stability of spantide II, a promising topical anti-inflammatory agent for the treatment of psoriasis and contact dermatitis
    • Kikwai L., Babu R.J., Kanikkannan N., Singh M. Preformulation stability of spantide II, a promising topical anti-inflammatory agent for the treatment of psoriasis and contact dermatitis. J Pharm Pharmacol 2004, 56:19-25.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 19-25
    • Kikwai, L.1    Babu, R.J.2    Kanikkannan, N.3    Singh, M.4
  • 11
    • 79960608561 scopus 로고    scopus 로고
    • Microdialysis assessment of percutaneous penetration of ketoprofen after transdermal administration to hairless rats and domestic pigs
    • Shinkai N., Korenaga K., Okumura Y., Mizu H., Yamauchi H. Microdialysis assessment of percutaneous penetration of ketoprofen after transdermal administration to hairless rats and domestic pigs. Eur J Pharm Biopharm 2011, 78:415-421.
    • (2011) Eur J Pharm Biopharm , vol.78 , pp. 415-421
    • Shinkai, N.1    Korenaga, K.2    Okumura, Y.3    Mizu, H.4    Yamauchi, H.5
  • 12
    • 67650064830 scopus 로고    scopus 로고
    • Investigation of polylactic acid (PLA) nanoparticles as drug delivery systems for local dermatotherapy
    • Rancan F., Papakostas D., Hadam S., Hackbarth S., Delair T., Primard C., et al. Investigation of polylactic acid (PLA) nanoparticles as drug delivery systems for local dermatotherapy. Pharm Res 2009, 26:2027-2036.
    • (2009) Pharm Res , vol.26 , pp. 2027-2036
    • Rancan, F.1    Papakostas, D.2    Hadam, S.3    Hackbarth, S.4    Delair, T.5    Primard, C.6
  • 14
    • 0034889150 scopus 로고    scopus 로고
    • Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection
    • Alvarez-Roman R., Barre G., Guy R.H., Fessi H. Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection. Eur J Pharm Biopharm 2001, 52:191-195.
    • (2001) Eur J Pharm Biopharm , vol.52 , pp. 191-195
    • Alvarez-Roman, R.1    Barre, G.2    Guy, R.H.3    Fessi, H.4
  • 15
    • 50149099948 scopus 로고    scopus 로고
    • Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy
    • Colonna C., Conti B., Perugini P., Pavanetto F., Modena T., Dorati R., et al. Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy. Eur J Pharm Biopharm 2008, 70:58-65.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 58-65
    • Colonna, C.1    Conti, B.2    Perugini, P.3    Pavanetto, F.4    Modena, T.5    Dorati, R.6
  • 16
    • 78649446481 scopus 로고    scopus 로고
    • Mechanistic study of hydrolytic erosion and drug release behaviour of PLGA nanoparticles: influence of chitosan
    • Jain G.K., Pathan S.A., Akhter S., Ahmad N., Jain N., Talegaonkar S., et al. Mechanistic study of hydrolytic erosion and drug release behaviour of PLGA nanoparticles: influence of chitosan. Polym Degrad Stab 2010, 95:2360-2366.
    • (2010) Polym Degrad Stab , vol.95 , pp. 2360-2366
    • Jain, G.K.1    Pathan, S.A.2    Akhter, S.3    Ahmad, N.4    Jain, N.5    Talegaonkar, S.6
  • 17
    • 77349092809 scopus 로고    scopus 로고
    • Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin
    • Senyigit T., Sonvico F., Barbieri S., Ozer O., Santi P., Colombo P. Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin. J Control Release 2010, 142:368-373.
    • (2010) J Control Release , vol.142 , pp. 368-373
    • Senyigit, T.1    Sonvico, F.2    Barbieri, S.3    Ozer, O.4    Santi, P.5    Colombo, P.6
  • 18
    • 3843149970 scopus 로고    scopus 로고
    • Enhancement of topical delivery from biodegradable nanoparticles
    • Alvarez-Roman R., Naik A., Kalia Y.N., Guy R.H., Fessi H. Enhancement of topical delivery from biodegradable nanoparticles. Pharm Res 2004, 21:1818-1825.
    • (2004) Pharm Res , vol.21 , pp. 1818-1825
    • Alvarez-Roman, R.1    Naik, A.2    Kalia, Y.N.3    Guy, R.H.4    Fessi, H.5
  • 20
    • 29244479590 scopus 로고    scopus 로고
    • Interactions of oleic acid and model stratum corneum membranes as seen by 2H NMR
    • Rowat A.C., Kitson N., Thewalt J.L. Interactions of oleic acid and model stratum corneum membranes as seen by 2H NMR. Int J Pharm 2006, 307:225-231.
    • (2006) Int J Pharm , vol.307 , pp. 225-231
    • Rowat, A.C.1    Kitson, N.2    Thewalt, J.L.3
  • 21
    • 0003082680 scopus 로고    scopus 로고
    • In vitro human skin barrier perturbation by oleic acid: thermal analysis and freeze fracture electron microscopy studies
    • Tanojo H., Bos-van Geest A., Bouwstra J.A., Junginger H.E., Boodé H.E. In vitro human skin barrier perturbation by oleic acid: thermal analysis and freeze fracture electron microscopy studies. Thermochimica Acta 1997, 293:77-85.
    • (1997) Thermochimica Acta , vol.293 , pp. 77-85
    • Tanojo, H.1    Bos-van Geest, A.2    Bouwstra, J.A.3    Junginger, H.E.4    Boodé, H.E.5
  • 22
    • 78049266209 scopus 로고    scopus 로고
    • Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin
    • Samah N.A., Williams N., Heard C.M. Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin. Int J Pharm 2010, 401:72-78.
    • (2010) Int J Pharm , vol.401 , pp. 72-78
    • Samah, N.A.1    Williams, N.2    Heard, C.M.3
  • 23
    • 78651378966 scopus 로고    scopus 로고
    • Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo skin distribution studies
    • Batheja P., Sheihet L., Kohn J., Singer A.J., Michniak-Kohn B. Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo skin distribution studies. J Control Release 2011, 149:159-167.
    • (2011) J Control Release , vol.149 , pp. 159-167
    • Batheja, P.1    Sheihet, L.2    Kohn, J.3    Singer, A.J.4    Michniak-Kohn, B.5
  • 24
    • 77953616889 scopus 로고    scopus 로고
    • The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery
    • Yuan X., Shah B.A., Kotadia N.K., Li J., Gu H., Wu Z. The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery. Pharm Res 2010, 27:1285-1295.
    • (2010) Pharm Res , vol.27 , pp. 1285-1295
    • Yuan, X.1    Shah, B.A.2    Kotadia, N.K.3    Li, J.4    Gu, H.5    Wu, Z.6
  • 25
    • 77953026370 scopus 로고    scopus 로고
    • Translocation of cell penetrating peptide engrafted nanoparticles across skin layers
    • Patlolla R.R., Desai P.R., Belay K., Singh M.S. Translocation of cell penetrating peptide engrafted nanoparticles across skin layers. Biomaterials 2010, 31:5598-5607.
    • (2010) Biomaterials , vol.31 , pp. 5598-5607
    • Patlolla, R.R.1    Desai, P.R.2    Belay, K.3    Singh, M.S.4
  • 26
    • 78649903242 scopus 로고    scopus 로고
    • Optimization of PEGylation conditions for BSA nanoparticles using response surface methodology
    • Kouchakzadeh H., Shojaosadati S., Maghsoudi A., Vasheghani Farahani E. Optimization of PEGylation conditions for BSA nanoparticles using response surface methodology. AAPSPharmSciTech 2010, 11:1206-1211.
    • (2010) AAPSPharmSciTech , vol.11 , pp. 1206-1211
    • Kouchakzadeh, H.1    Shojaosadati, S.2    Maghsoudi, A.3    Vasheghani Farahani, E.4
  • 27
    • 67349280651 scopus 로고    scopus 로고
    • Nanoparticle coated submicron emulsions: sustained in vitro release and improved dermal delivery of all-trans-retinol
    • Ghouchi Eskandar N., Simovic S., Prestidge C. Nanoparticle coated submicron emulsions: sustained in vitro release and improved dermal delivery of all-trans-retinol. Pharm Res 2009, 26:1764-1775.
    • (2009) Pharm Res , vol.26 , pp. 1764-1775
    • Ghouchi Eskandar, N.1    Simovic, S.2    Prestidge, C.3
  • 28
    • 66949162673 scopus 로고    scopus 로고
    • Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
    • van der Fits L., Mourits S., Voerman J.S., Kant M., Boon L., Laman J.D., et al. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol 2009, 182:5836-5845.
    • (2009) J Immunol , vol.182 , pp. 5836-5845
    • van der Fits, L.1    Mourits, S.2    Voerman, J.S.3    Kant, M.4    Boon, L.5    Laman, J.D.6
  • 29
    • 33750983004 scopus 로고    scopus 로고
    • In vitro and in vivo comparison of dermal irritancy of jet fuel exposure using EpiDerm (EPI-200) cultured human skin and hairless rats
    • Chatterjee A., Babu R., Klausner M., Singh M. In vitro and in vivo comparison of dermal irritancy of jet fuel exposure using EpiDerm (EPI-200) cultured human skin and hairless rats. Toxicol Lett 2005, 167:85-94.
    • (2005) Toxicol Lett , vol.167 , pp. 85-94
    • Chatterjee, A.1    Babu, R.2    Klausner, M.3    Singh, M.4
  • 30
    • 79952637468 scopus 로고    scopus 로고
    • Antitumor activity of noscapine in combination with doxorubicin in triple negative breast cancer
    • Chougule M.B., Patel A., Jackson T., Singh M. Antitumor activity of noscapine in combination with doxorubicin in triple negative breast cancer. PLoS One 2011, 6:e17733.
    • (2011) PLoS One , vol.6
    • Chougule, M.B.1    Patel, A.2    Jackson, T.3    Singh, M.4
  • 31
    • 79851512201 scopus 로고    scopus 로고
    • Anticancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer
    • Chougule M.B., Patel A.R., Sachdeva P., Jackson T., Singh M. Anticancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer. Lung Cancer 2011, 71:271-282.
    • (2011) Lung Cancer , vol.71 , pp. 271-282
    • Chougule, M.B.1    Patel, A.R.2    Sachdeva, P.3    Jackson, T.4    Singh, M.5
  • 32
    • 67349129109 scopus 로고    scopus 로고
    • Thixotropic property in pharmaceutical formulations
    • Lee C.H., Moturi V., Lee Y. Thixotropic property in pharmaceutical formulations. J Control Release 2009, 136:88-98.
    • (2009) J Control Release , vol.136 , pp. 88-98
    • Lee, C.H.1    Moturi, V.2    Lee, Y.3
  • 33
    • 78651373680 scopus 로고    scopus 로고
    • The influence of various silicones on the rheological parameters of AZG containing silicone-based gels
    • Mortazavi S.A., Tabandeh H. The influence of various silicones on the rheological parameters of AZG containing silicone-based gels. Iran J Pharm Res 2005, 4:205-211.
    • (2005) Iran J Pharm Res , vol.4 , pp. 205-211
    • Mortazavi, S.A.1    Tabandeh, H.2
  • 34
    • 0033044064 scopus 로고    scopus 로고
    • Rheological characterization of hydroxypropylcellulose gels
    • Ramachandran S., Chen S., Etzler F. Rheological characterization of hydroxypropylcellulose gels. Drug Dev Ind Pharm 1999, 25:153-161.
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 153-161
    • Ramachandran, S.1    Chen, S.2    Etzler, F.3
  • 36
    • 0028361592 scopus 로고
    • Structural rheology of a model ointment
    • Pena L.E., Lee B.L., Stearns J.F. Structural rheology of a model ointment. Pharm Res 1994, 11:875-881.
    • (1994) Pharm Res , vol.11 , pp. 875-881
    • Pena, L.E.1    Lee, B.L.2    Stearns, J.F.3
  • 37
    • 0036692338 scopus 로고    scopus 로고
    • Network structure of cellulose ethers used in pharmaceutical applications during swelling and at equilibrium
    • Baumgartner S., Kristl J., Peppas N.A. Network structure of cellulose ethers used in pharmaceutical applications during swelling and at equilibrium. Pharm Res 2002, 19:1084-1090.
    • (2002) Pharm Res , vol.19 , pp. 1084-1090
    • Baumgartner, S.1    Kristl, J.2    Peppas, N.A.3
  • 38
    • 77956226428 scopus 로고    scopus 로고
    • Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis
    • Pople P., Singh K.K. Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis. Int J Pharm 2010, 398:165-178.
    • (2010) Int J Pharm , vol.398 , pp. 165-178
    • Pople, P.1    Singh, K.K.2
  • 39
    • 42749086446 scopus 로고    scopus 로고
    • Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation
    • Puglia C., Blasi P., Rizza L., Schoubben A., Bonina F., Rossi C., et al. Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation. Int J Pharm 2008, 357:295-304.
    • (2008) Int J Pharm , vol.357 , pp. 295-304
    • Puglia, C.1    Blasi, P.2    Rizza, L.3    Schoubben, A.4    Bonina, F.5    Rossi, C.6
  • 40
    • 77956637950 scopus 로고    scopus 로고
    • Protective effects of black rice bran against chemically-induced inflammation of mouse skin
    • Choi S.P., Kim S.P., Kang M.Y., Nam S.H., Friedman M. Protective effects of black rice bran against chemically-induced inflammation of mouse skin. J Agric Food Chem 2010, 58:10007-10015.
    • (2010) J Agric Food Chem , vol.58 , pp. 10007-10015
    • Choi, S.P.1    Kim, S.P.2    Kang, M.Y.3    Nam, S.H.4    Friedman, M.5
  • 42
    • 79959253727 scopus 로고    scopus 로고
    • Analysis of the potential topical anti-inflammatory activity of averrhoa carambola L. in mice
    • Available from:
    • Cabrini D.A., Moresco H., Imazu P., da Silva C.D., Pietrovski E.F., Mendes D.A., et al. Analysis of the potential topical anti-inflammatory activity of averrhoa carambola L. in mice. Evid Based Complement Alternat Med 2011, Available from:. http://www.hindawi.com/journals/ecam/2011/908059/, 10.1093/ecam/neq026).
    • (2011) Evid Based Complement Alternat Med
    • Cabrini, D.A.1    Moresco, H.2    Imazu, P.3    da Silva, C.D.4    Pietrovski, E.F.5    Mendes, D.A.6
  • 43
    • 61449176345 scopus 로고    scopus 로고
    • NF-kappa-B links keratinocytes and lymphocytes in the pathogenesis of psoriasis
    • Tsuruta D. NF-kappa-B links keratinocytes and lymphocytes in the pathogenesis of psoriasis. Recent Pat Inflamm Allergy Drug Discov 2009, 3:40-48.
    • (2009) Recent Pat Inflamm Allergy Drug Discov , vol.3 , pp. 40-48
    • Tsuruta, D.1
  • 44
    • 77955352799 scopus 로고    scopus 로고
    • Skin inflammation induced by the synergistic action of IL-17A, IL-22, oncostatin M, IL-1{alpha}, and TNF-{alpha} recapitulates some features of psoriasis
    • Guilloteau K., Paris I., Pedretti N., Boniface K., Juchaux F., Huguier V., et al. Skin inflammation induced by the synergistic action of IL-17A, IL-22, oncostatin M, IL-1{alpha}, and TNF-{alpha} recapitulates some features of psoriasis. J Immunol 2010, 184:5263-5270.
    • (2010) J Immunol , vol.184 , pp. 5263-5270
    • Guilloteau, K.1    Paris, I.2    Pedretti, N.3    Boniface, K.4    Juchaux, F.5    Huguier, V.6
  • 45
    • 0029844041 scopus 로고    scopus 로고
    • Effect of a novel topical immunomodulator, S-28463, on keratinocyte cytokine gene expression and production
    • Fujisawa H., Shivji G., Kondo S., Wang B., Tomai M.A., Miller R.L., et al. Effect of a novel topical immunomodulator, S-28463, on keratinocyte cytokine gene expression and production. J Interferon Cytokine Res 1996, 16:555-559.
    • (1996) J Interferon Cytokine Res , vol.16 , pp. 555-559
    • Fujisawa, H.1    Shivji, G.2    Kondo, S.3    Wang, B.4    Tomai, M.A.5    Miller, R.L.6
  • 46
    • 0028861884 scopus 로고
    • Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema
    • Inoue H., Nagata N., Koshihara Y. Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema. Inflamm Res 1995, 44:470-474.
    • (1995) Inflamm Res , vol.44 , pp. 470-474
    • Inoue, H.1    Nagata, N.2    Koshihara, Y.3
  • 47
    • 47549101407 scopus 로고    scopus 로고
    • Skin application of the nonsteroidal anti-inflammatory drug ketoprofen downmodulates the antigen-presenting ability of langerhans cells in mice
    • Atarashi K., Kabashima K., Akiyama K., Tokura Y. Skin application of the nonsteroidal anti-inflammatory drug ketoprofen downmodulates the antigen-presenting ability of langerhans cells in mice. Br J Dermatol 2008, 159:306-313.
    • (2008) Br J Dermatol , vol.159 , pp. 306-313
    • Atarashi, K.1    Kabashima, K.2    Akiyama, K.3    Tokura, Y.4
  • 48
    • 40949116663 scopus 로고    scopus 로고
    • Topical treatment of mild to moderate plaque psoriasis with 0.3% tacrolimus gel and 0.5% tacrolimus cream: the effect on SUM score, epidermal proliferation, keratinization, T-cell subsets and HLA-DR expression
    • Vissers W.H., van Vlijmen I., van Erp P.E., de Jong E.M., van de Kerkhof P.C. Topical treatment of mild to moderate plaque psoriasis with 0.3% tacrolimus gel and 0.5% tacrolimus cream: the effect on SUM score, epidermal proliferation, keratinization, T-cell subsets and HLA-DR expression. Br J Dermatol 2008, 158:705-712.
    • (2008) Br J Dermatol , vol.158 , pp. 705-712
    • Vissers, W.H.1    van Vlijmen, I.2    van Erp, P.E.3    de Jong, E.M.4    van de Kerkhof, P.C.5


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