Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine

Journal of Controlled Release

Volumn 179, Issue 1, 2014, Pages 11-17

  Kim, Nak Won ^a   Lee, Min Sang ^a   Kim, Kyu Ri ^b   Lee, Jung Eun ^a   Lee, Kyuri ^a   Park, Jong Sung ^a   Matsumoto, Yoh ^c   Jo, Dong Gyu ^a   Lee, Haeshin ^b   Lee, Doo Sung ^a   Jeong, Ji Hoon ^a  

^a Sungkyunkwan University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

DNA vaccine; Gene delivery; Layer by layer assembly; Microneedle array; pH responsive materials

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ANTIBODY; DNA VACCINE; PEPTIDE FRAGMENT; POLYMER;

ANIMAL; ANTIGEN PRESENTING CELL; BAGG ALBINO MOUSE; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DEVICES; DRUG EFFECTS; ELECTRONICS; EQUIPMENT DESIGN; FEMALE; GENE TRANSFER; GENETICS; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MOUSE; NEEDLE; PH; SKIN; SUBCUTANEOUS DRUG ADMINISTRATION; TIME;

AMYLOID BETA-PEPTIDES; ANIMALS; ANTIBODIES; ANTIGEN-PRESENTING CELLS; EQUIPMENT DESIGN; FEMALE; GENE TRANSFER TECHNIQUES; HYDROGEN-ION CONCENTRATION; IMMUNITY, HUMORAL; IMMUNIZATION; IMMUNOLOGIC MEMORY; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED BALB C; MINIATURIZATION; NEEDLES; PEPTIDE FRAGMENTS; POLYMERS; SKIN; TIME FACTORS; VACCINES, DNA;

EID: 84893903503     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.01.016     Document Type: Article

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