Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza

Journal of Controlled Release

Volumn 160, Issue 3, 2012, Pages 495-501

  Matsuo, Kazuhiko ^a   Hirobe, Sachiko ^a   Yokota, Yayoi ^a   Ayabe, Yurika ^a   Seto, Masashi ^a   Quan, Ying Shu ^b   Kamiyama, Fumio ^b   Tougan, Takahiro ^c   Horii, Toshihiro ^c   Mukai, Yohei ^a   Okada, Naoki ^a   Nakagawa, Shinsaku ^a  

^a OSAKA UNIVERSITY   (Japan)

^b CosMED Pharmaceutical Co Ltd ^*  (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Diphtheria; Dissolving microneedle array; Influenza; Malaria; Tetanus; Transcutaneous immunization

Indexed keywords

DIPHTHERIA; INFLUENZA; MALARIA; MICRONEEDLE ARRAYS; TETANUS; TRANSCUTANEOUS;

ANTIBODIES; IMMUNIZATION; IMMUNOLOGY; NEEDLES; VACCINES; VIRUSES;

DISSOLUTION;

DIPHTHERIA VACCINE; IMMUNOGLOBULIN G; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; MALARIA VACCINE; NEUTRALIZING ANTIBODY; SE36 VACCINE; TETANUS TOXOID; TOXIN ANTIBODY; TOXOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DIPHTHERIA; DRUG EFFICACY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA; INFLUENZA VIRUS; MALARIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TETANUS; TRANSCUTANEOUS IMMUNIZATION; VACCINATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIGENS, PROTOZOAN; DIPHTHERIA TOXIN; DIPHTHERIA TOXOID; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; IMMUNIZATION; INFLUENZA VACCINES; MALARIA VACCINES; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; NEEDLES; RATS; RATS, HAIRLESS; TETANUS TOXIN; TETANUS TOXOID;

EID: 84861977586     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.04.001     Document Type: Article

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