Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

Journal of Controlled Release

Volumn 189, Issue , 2014, Pages 141-149

  Mccarthy, Helen O ^a   McCaffrey, Joanne ^a   Mccrudden, Cian M ^a   Zholobenko, Aleksey ^a   Ali, Ahlam A ^a   McBride, John W ^a   Massey, Ashley S ^a   Pentlavalli, Sreekanth ^a   Chen, Kun Hung ^a   Cole, Grace ^a   Loughran, Stephen P ^a   Dunne, Nicholas J ^a   Donnelly, Ryan F ^a   Kett, Victoria L ^a   Robson, Tracy ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Amphipathic peptide; Biological barriers; Cell penetrating peptide; DNA delivery; Nanoparticle

Indexed keywords

BIOMOLECULES; CELL CULTURE; CELL MEMBRANES; DRUG THERAPY; GENE EXPRESSION; GENE TRANSFER; NANOPARTICLES; NUCLEIC ACIDS;

AMPHIPATHIC PEPTIDES; BIOLOGICAL BARRIER; CELL-PENETRATING PEPTIDE; DNA DELIVERY; ENZYMATIC DEGRADATION; FUNCTIONAL NUCLEIC ACIDS; NON-VIRAL GENE DELIVERY; REPORTER-GENE EXPRESSION;

PEPTIDES;

NANOCARRIER; PEPTIDE DERIVATIVE; PLASMID DNA; RALA PEPTIDE; UNCLASSIFIED DRUG; DNA; FIREFLY LUCIFERASE; NANOPARTICLE; PEPTIDE;

ALPHA HELIX; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER CELL LINE; CELL MEMBRANE; CHEMICAL PHENOMENA; COMPLEX FORMATION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DRUG EFFICACY; FEMALE; FIBROBLAST CULTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; REPORTER GENE; SYSTEMIC THERAPY; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECTS; ERYTHROCYTE; GENE TRANSFER; GENETICS; HEMOLYSIS; METABOLISM; PLASMID; SHEEP; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; ERYTHROCYTES; FEMALE; GENE TRANSFER TECHNIQUES; HEMOLYSIS; HUMANS; LUCIFERASES, FIREFLY; MICE, INBRED C57BL; NANOPARTICLES; PARTICLE SIZE; PEPTIDES; PLASMIDS; SHEEP;

EID: 84904340550     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.06.048     Document Type: Article

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