The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches

Archives of Biochemistry and Biophysics

Volumn 591, Issue , 2016, Pages 111-131

  Simmons, Rachel D ^a   Kumar, Sandeep ^a   Jo, Hanjoong ^a,b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Blood flow; Endothelial cells; Epigenomics; Genomics; Mechanosensitive; Metabolomics; miRNomics; Shear stress

Indexed keywords

DNA; TRANSCRIPTOME; PROTEOME;

ARTERY; ATHEROSCLEROSIS; ENDOTHELIAL MECHANOSENSITIVE GENE; EX VIVO STUDY; EXPERIMENTAL MODEL; GENE; GENOME; HEMODYNAMICS; HUMAN; IN VITRO STUDY; MECHANOTRANSDUCTION; METABOLOME; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEOMICS; REVIEW; TRANSCRIPTOMICS; ANIMAL; BLOOD FLOW VELOCITY; BLOOD PRESSURE; METABOLISM; PATHOPHYSIOLOGY; PROCEDURES; VASCULAR ENDOTHELIUM;

ANIMALS; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; ENDOTHELIUM, VASCULAR; HUMANS; MECHANOTRANSDUCTION, CELLULAR; PROTEOME; PROTEOMICS;

EID: 84952332437     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2015.11.005     Document Type: Review

References (402)

1. A.M. Malek, S.L. Alper, and S. Izumo JAMA 282 1999 2035 2042
2. M. LaBarbera Science 249 1990 992 1000
3. X. Girerd, G. London, P. Boutouyrie, J.J. Mourad, M. Safar, and S. Laurent Hypertension 27 1996 799 803
4. A. Kamiya, R. Bukhari, and T. Togawa Bull. Math. Biol. 46 1984 127 137
5. S. Rossitti, and J. Lofgren Stroke 24 1993 371 377
6. A. Gnasso, C. Carallo, C. Irace, M.S. De Franceschi, P.L. Mattioli, C. Motti, and C. Cortese Atherosclerosis 156 2001 171 176
7. Y. Jiang, K. Kohara, and K. Hiwada Hypertens. Res. 22 1999 203 207
8. R. Joannides, C. Bizet-Nafeh, A. Costentin, M. Iacob, G. Derumeaux, A. Cribier, and C. Thuillez Hypertension 38 2001 1446 1450
9. L.A. Taber, S. Ng, A.M. Quesnel, J. Whatman, and C.J. Carmen J. Biomech. 34 2001 121 124
10. L.A. Taber Biophys. J. 74 1998 109 114
11. M. Zamir J. Gen. Physiol. 69 1977 449 461
12. C.D. Murray Proc. Natl. Acad. Sci. U. S. A. 12 1926 207 214
13. C.D. Murray J. Gen. Physiol. 9 1926 835 841
14. S.P. Wu, S. Ringgaard, S. Oyre, M.S. Hansen, S. Rasmus, and E.M. Pedersen J. Magn. Reson. Imaging 19 2004 188 193
15. L. Kornet, A.P. Hoeks, J. Lambregts, and R.S. Reneman J. Vasc. Res. 37 2000 112 122
16. C.P. Cheng, R.J. Herfkens, and C.A. Taylor Atherosclerosis 168 2003 323 331
17. A. Gnasso, C. Carallo, C. Irace, V. Spagnuolo, G. De Novara, P.L. Mattioli, and A. Pujia Circulation 94 1996 3257 3262
18. H.A. Silber, P. Ouyang, D.A. Bluemke, S.N. Gupta, T.K. Foo, and J.A. Lima Am. J. Physiol. Heart Circ. Physiol. 288 2005 H822 H828
19. H. Gaenzer, G. Neumayr, P. Marschang, W. Sturm, R. Kirchmair, and J.R. Patsch J. Am. Coll. Cardiol. 38 2001 1313 1319
20. B.T. Tang, C.P. Cheng, M.T. Draney, N.M. Wilson, P.S. Tsao, R.J. Herfkens, and C.A. Taylor Am. J. Physiol. Heart Circ. Physiol. 291 2006 H668 H676
21. E.M. Pedersen, S. Oyre, M. Agerbaek, I.B. Kristensen, S. Ringgaard, P. Boesiger, and W.P. Paaske Eur. J. Vasc. Endovasc. Surg. 18 1999 328 333
22. S. Oyre, E.M. Pedersen, S. Ringgaard, P. Boesiger, and W.P. Paaske Eur. J. Vasc. Endovasc. Surg. 13 1997 263 271
23. J.N. Oshinski, D.N. Ku, S. Mukundan Jr., F. Loth, and R.I. Pettigrew J. Magn. Reson. Imaging 5 1995 640 647
24. S.K. Samijo, J.M. Willigers, R. Barkhuysen, P.J. Kitslaar, R.S. Reneman, P.J. Brands, and A.P. Hoeks Cardiovasc. Res. 39 1998 515 522
25. S. Oyre, S. Ringgaard, S. Kozerke, W.P. Paaske, M. Erlandsen, P. Boesiger, and E.M. Pedersen J. Am. Coll. Cardiol. 32 1998 128 134
26. R. Dammers, F. Stifft, J.H. Tordoir, J.M. Hameleers, A.P. Hoeks, and P.J. Kitslaar J. Appl. Physiol. 94 2003 1985 485 489
27. Y.H. Li, A.K. Reddy, G.E. Taffet, L.H. Michael, M.L. Entman, and C.J. Hartley Ultrasound Med. Biol. 29 2003 1281 1289
28. G. Ross, F.N. White, A.W. Brown, and A. Kolin J. Appl. Physiol. 21 1966 1273 1275
29. G. Marano, S. Palazzesi, A. Vergari, and A.U. Ferrari Arterioscler. Thromb. Vasc. Biol. 19 1999 2609 2614
30. A. Kamiya, and T. Togawa Am. J. Physiol. 239 1980 H14 H21
31. S.P. Wu, S. Ringgaard, and E.M. Pedersen Magn. Reson. Imaging 22 2004 345 351
32. C. Cheng, F. Helderman, D. Tempel, D. Segers, B. Hierck, R. Poelmann, A. van Tol, D.J. Duncker, D. Robbers-Visser, N.T. Ursem, R. van Haperen, J.J. Wentzel, F. Gijsen, A.F. van der Steen, R. de Crom, and R. Krams Atherosclerosis 195 2007 225 235
33. R. de Crom, C. Cheng, F. Helderman, and R. Krams Atherosclerosis 204 2009 16 17 (author reply 18-19)
34. H. Masuda, Y.J. Zhuang, T.M. Singh, K. Kawamura, M. Murakami, C.K. Zarins, and S. Glagov Arterioscler. Thromb. Vasc. Biol. 19 1999 2298 2307
35. J.K. Miyashiro, V. Poppa, and B.C. Berk Circ. Res. 81 1997 311 319
36. J. Ibrahim, J.K. Miyashiro, and B.C. Berk Circ. Res. 92 2003 1001 1009
37. K. Lee, M. Choi, J. Yoon, and J. Jung Vet. Radiol. Ultrasound 45 2004 166 171
38. M. Lie, O.M. Sejersted, and F. Kiil Circ. Res. 27 1970 727 737
39. S. Serhatlioglu, A. Kiris, E. Kocakoc, I. Canpolat, Z. Bozgeyik, and M.C. Han Urol. Int. 71 2003 103 107
40. U. Pohl, J. Holtz, R. Busse, and E. Bassenge Hypertension 8 1986 37 44
41. H. Samady, P. Eshtehardi, M.C. McDaniel, J. Suo, S.S. Dhawan, C. Maynard, L.H. Timmins, A.A. Quyyumi, and D.P. Giddens Circulation 124 2011 779 788
42. J. Suo, D.E. Ferrara, D. Sorescu, R.E. Guldberg, W.R. Taylor, and D.P. Giddens Arterioscler. Thromb. Vasc. Biol. 27 2007 346 351
43. D. Nam, C.W. Ni, A. Rezvan, J. Suo, K. Budzyn, A. Llanos, D. Harrison, D. Giddens, and H. Jo Am. J. Physiol. Heart Circ. Physiol. 297 2009 H1535 H1543
44. M. Domanski, D. Lloyd-Jones, V. Fuster, and S. Grundy Nat. Rev. Cardiol. 8 2011 721 725
45. R. Glaser, F. Selzer, D.P. Faxon, W.K. Laskey, H.A. Cohen, J. Slater, K.M. Detre, and R.L. Wilensky Circulation 111 2005 143 149
46. A.V. Finn, M. Nakano, J. Narula, F.D. Kolodgie, and R. Virmani Arterioscler. Thromb. Vasc. Biol. 30 2010 1282 1292
47. A.V. Finn, and R.K. Jain JACC Cardiovasc. Imaging 3 2010 41 44
48. N. Maldonado, A. Kelly-Arnold, Y. Vengrenyuk, D. Laudier, J.T. Fallon, R. Virmani, L. Cardoso, and S. Weinbaum Am. J. Physiol. Heart Circ. Physiol. 303 2012 H619 H628
49. D.M. Spain Sci. Am. 215 1966 48 56
50. J. Suo, J.N. Oshinski, and D.P. Giddens Mol. Cell. Biomech. 5 2008 9 18
51. D.A. Steinman, and C.A. Taylor Ann. Biomed. Eng. 33 2005 1704 1709
52. P.F. Davies, D.C. Polacek, J.S. Handen, B.P. Helmke, and N. DePaola Trends Biotechnol. 17 1999 347 351
53. P. Libby Am. J. Cardiol. 86 2000 3J 8J (discussion 8J-9J)
54. C.G. Caro, J.M. Fitz-Gerald, and R.C. Schroter Nature 223 1969 1159 1160
55. C.G. Caro Arterioscler. Thromb. Vasc. Biol. 29 2009 158 161
56. C.G. Caro, and R.M. Nerem Circ. Res. 32 1973 187 205
57. M.H. Friedman, G.M. Hutchins, C.B. Bargeron, O.J. Deters, and F.F. Mark J. Biomech. Eng. 103 1981 204 207
58. M.H. Friedman, G.M. Hutchins, C.B. Bargeron, O.J. Deters, and F.F. Mark Atherosclerosis 39 1981 425 436
59. C.K. Zarins, D.P. Giddens, B.K. Bharadvaj, V.S. Sottiurai, R.F. Mabon, and S. Glagov Circ. Res. 53 1983 502 514
60. D.N. Ku, D.P. Giddens, C.K. Zarins, and S. Glagov Arteriosclerosis 5 1985 293 302
61. S. Tada, and J.M. Tarbell Ann. Biomed. Eng. 33 2005 1202 1212
62. P.F. Davies Nat. Clin. Pract. Cardiovasc. Med. 6 2009 16 26
63. R.L. Janiczek, B.R. Blackman, R.J. Roy, C.H. Meyer, S.T. Acton, and F.H. Epstein Magn. Reson. Med. 66 2011 1382 1390
64. R.M. Nerem, M.J. Levesque, and J.F. Cornhill J. Biomech. Eng. 103 1981 172 176
65. C.F. Dewey Jr., S.R. Bussolari, M.A. Gimbrone Jr., and P.F. Davies J. Biomech. Eng. 103 1981 177 185
66. J.A. Frangos, S.G. Eskin, L.V. McIntire, and C.L. Ives Science 227 1985 1477 1479
67. E.F. Grabowski, E.A. Jaffe, and B.B. Weksler J. Lab. Clin. Med. 105 1985 36 43
68. M. Mo, S.G. Eskin, and W.P. Schilling Am. J. Physiol. 260 1991 H1698 H1707
69. J. Shen Zhonghua Yi Xue Za Zhi 71 1991 488 491 434
70. M.J. Kuchan, H. Jo, and J.A. Frangos Am. J. Physiol. 267 1994 C753 C758
71. M.J. Kuchan, and J.A. Frangos Am. J. Physiol. 266 1994 C628 C636
72. R. Korenaga, J. Ando, H. Tsuboi, W. Yang, I. Sakuma, T. Toyo-oka, and A. Kamiya Biochem. Biophys. Res. Commun. 198 1994 213 219
73. H. Jo, R.O. Dull, T.M. Hollis, and J.M. Tarbell Am. J. Physiol. 260 1991 H1992 H1996
74. C.M. Warboys, R. Eric Berson, G.E. Mann, J.D. Pearson, P.D. Weinberg, Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules, 2010.
75. I. Kurose, S. Miura, D. Fukumura, and M. Tsuchiya Eur. J. Pharmacol. 250 1993 85 94
76. A.L. Baldwin, G. Thurston, and H. al Naemi Am. J. Physiol. 274 1998 H1776 H1784
77. M.V. Hillsley, and J.M. Tarbell Biochem. Biophys. Res. Commun. 293 2002 1466 1471
78. J.M. Tarbell Cardiovasc. Res. 87 2010 320 330
79. D.J. Son, S. Kumar, W. Takabe, C.W. Kim, C.W. Ni, N. Alberts-Grill, I.H. Jang, S. Kim, W. Kim, S. Won Kang, A.H. Baker, J. Woong Seo, K.W. Ferrara, and H. Jo Nat. Commun. 4 2013 3000
80. J. Huynh, N. Nishimura, K. Rana, J.M. Peloquin, J.P. Califano, C.R. Montague, M.R. King, C.B. Schaffer, and C.A. Reinhart-King Sci. Transl. Med. 3 2011 112ra122
81. C.W. Kim, S. Kumar, D.J. Son, I.H. Jang, K.K. Griendling, and H. Jo Arterioscler. Thromb. Vasc. Biol. 34 2014 1412 1421
82. S.L. Tressel, R.P. Huang, N. Tomsen, and H. Jo Arterioscler. Thromb. Vasc. Biol. 27 2007 2150 2156
83. M. Harrison, E. Smith, E. Ross, R. Krams, D. Segers, C.D. Buckley, G.B. Nash, and G.E. Rainger Arterioscler. Thromb. Vasc. Biol. 33 2013 694 701
84. S. Chien, J.J. Chiu, and Y.S. Li Am. J. Physiol. Cell Physiol. 297 2009 C800 C801
85. J.J. Chiu, S. Usami, and S. Chien Ann. Med. 41 2009 19 28
86. L. Hajra, A.I. Evans, M. Chen, S.J. Hyduk, T. Collins, and M.I. Cybulsky Proc. Natl. Acad. Sci. U. S. A. 97 2000 9052 9057
87. A.G. Passerini, D.C. Polacek, C. Shi, N.M. Francesco, E. Manduchi, G.R. Grant, W.F. Pritchard, S. Powell, G.Y. Chang, C.J. Stoeckert Jr., and P.F. Davies Proc. Natl. Acad. Sci. U. S. A. 101 2004 2482 2487
88. S.R. Bussolari, C.F. Dewey Jr., and M.A. Gimbrone Jr. The review of scientific instruments 53 1982 1851 1854
89. R.P. Franke, M. Grafe, H. Schnittler, D. Seiffge, C. Mittermayer, and D. Drenckhahn Nature 307 1984 648 649
90. Y.M. Go, Y.C. Boo, H. Park, M.C. Maland, R. Patel, K.A. Pritchard Jr., Y. Fujio, K. Walsh, V. Darley-Usmar, and H. Jo J. Appl. Physiol. 91 2001 1985 1574 1581
91. H. Jo, H. Song, and A. Mowbray Antioxid. Redox Signal 8 2006 1609 1619
92. J.A. Frangos, L.V. McIntire, and S.G. Eskin Biotechnol. Bioeng. 32 1988 1053 1060
93. U.Y. Schaff, M.M. Xing, K.K. Lin, N. Pan, N.L. Jeon, and S.I. Simon Lab. Chip 7 2007 448 456
94. N.E. Ashpole, D.R. Overby, C.R. Ethier, and W.D. Stamer Investig. Ophthalmol. Vis. Sci. 55 2014 8067 8076
95. A. Ganguly, H. Zhang, R. Sharma, S. Parsons, and K.D. Patel J. Vis. Exp. 66 2012 Aug 8 e4032 10.3791/4032
96. A. Rezvan, C.W. Ni, N. Alberts-Grill, and H. Jo Antioxid. Redox Signal 15 2011 1433 1448
97. N. Bardy, G.J. Karillon, R. Merval, J.L. Samuel, and A. Tedgui Circ. Res. 77 1995 684 694
98. V. Gambillara, C. Chambaz, G. Montorzi, S. Roy, N. Stergiopulos, and P. Silacci Am. J. Physiol. Heart Circ. Physiol. 290 2006 H2320 H2328
99. X. Lu, and G.S. Kassab J. Physiol. 561 2004 575 582
100. R.L. Gleason, S.P. Gray, E. Wilson, and J.D. Humphrey J. Biomech. Eng. 126 2004 787 795
101. B. Paigen, A. Morrow, P.A. Holmes, D. Mitchell, and R.A. Williams Atherosclerosis 68 1987 231 240
102. B. Paigen, P.A. Holmes, D. Mitchell, and D. Albee Atherosclerosis 64 1987 215 221
103. B. Paigen, A. Morrow, C. Brandon, D. Mitchell, and P. Holmes Atherosclerosis 57 1985 65 73
104. B. Paigen, M.B. Havens, and A. Morrow Cancer Res. 45 1985 3850 3855
105. J.A. Piedrahita, S.H. Zhang, J.R. Hagaman, P.M. Oliver, and N. Maeda Proc. Natl. Acad. Sci. U. S. A. 89 1992 4471 4475
106. A.S. Plump, J.D. Smith, T. Hayek, K. Aalto-Setala, A. Walsh, J.G. Verstuyft, E.M. Rubin, and J.L. Breslow Cell 71 1992 343 353
107. S.H. Zhang, R.L. Reddick, J.A. Piedrahita, and N. Maeda Science 258 1992 468 471
108. S. Ishibashi, J. Herz, N. Maeda, J.L. Goldstein, and M.S. Brown Proc. Natl. Acad. Sci. U. S. A. 91 1994 4431 4435
109. A.H. Lichtman, S.K. Clinton, K. Iiyama, P.W. Connelly, P. Libby, and M.I. Cybulsky Arterioscler. Thromb. Vasc. Biol. 19 1999 1938 1944
110. N.J. Hardin, C.R. Minick, and G.E. Murphy Am. J. Pathol. 73 1973 301 326
111. A.M. Melkumyants, S.A. Balashov, and V.M. Khayutin Cardiovasc. Res. 23 1989 741 747
112. A.W. Clowes, G.B. Ryan, J.L. Breslow, and M.J. Karnovsky Lab. Investig. 35 1976 6 17
113. V. Lindner, J. Fingerle, and M.A. Reidy Circ. Res. 73 1993 792 796
114. G.Z. Feuerstein, and R.R. Ruffolo Jr. Eur. Heart J. 17 Suppl. B 1996 24 29
115. T. Morishita, M. Tsutsui, H. Shimokawa, M. Horiuchi, A. Tanimoto, O. Suda, H. Tasaki, P.L. Huang, Y. Sasaguri, N. Yanagihara, and Y. Nakashima FASEB J. 16 2002 1994 1996
116. S.C. Hollestelle, M.R. De Vries, J.K. Van Keulen, A.H. Schoneveld, A. Vink, C.F. Strijder, B.J. Van Middelaar, G. Pasterkamp, P.H. Quax, and D.P. De Kleijn Circulation 109 2004 393 398
117. J.H. Lardenoye, D.J. Delsing, M.R. de Vries, M.M. Deckers, H.M. Princen, L.M. Havekes, V.W. van Hinsbergh, J.H. van Bockel, and P.H. Quax Circ. Res. 87 2000 248 253
118. Y. Sasaguri, K.Y. Wang, A. Tanimoto, M. Tsutsui, H. Ueno, Y. Murata, Y. Kohno, S. Yamada, and H. Ohtsu Circ. Res. 96 2005 974 981
119. V. da Cunha, B. Martin-McNulty, J. Vincelette, D.F. Choy, W.W. Li, M. Schroeder, M. Mahmoudi, M. Halks-Miller, D.W. Wilson, R. Vergona, M.E. Sullivan, and Y.X. Wang J. Vasc. Surg. 44 2006 364 371
120. E. Ivan, J.J. Khatri, C. Johnson, R. Magid, D. Godin, S. Nandi, S. Lessner, and Z.S. Galis Circulation 105 2002 2686 2691
121. A.C. Jonsson-Rylander, T. Nilsson, R. Fritsche-Danielson, A. Hammarstrom, M. Behrendt, J.O. Andersson, K. Lindgren, A.K. Andersson, P. Wallbrandt, B. Rosengren, P. Brodin, A. Thelin, A. Westin, E. Hurt-Camejo, and C.H. Lee-Sogaard Arterioscler. Thromb. Vasc. Biol. 25 2005 180 185
122. J.E. Leidenfrost, M.F. Khan, K.P. Boc, B.R. Villa, E.T. Collins, W.C. Parks, D.R. Abendschein, and E.T. Choi Am. J. Pathol. 163 2003 773 778
123. S.L. Liu, Y.H. Li, G.Y. Shi, S.H. Tang, S.J. Jiang, C.W. Huang, P.Y. Liu, J.S. Hong, and H.L. Wu Cardiovasc. Res. 82 2009 161 169
124. K. Nakamura, T. Sasaki, X.W. Cheng, A. Iguchi, K. Sato, and M. Kuzuya Atherosclerosis 206 2009 355 361
125. M. Rekhter, K. Staschke, T. Estridge, P. Rutherford, N. Jackson, D. Gifford-Moore, P. Foxworthy, C. Reidy, X.D. Huang, M. Kalbfleisch, K. Hui, M.S. Kuo, R. Gilmour, and C.J. Vlahos Biochem. Biophys. Res. Commun. 367 2008 642 648
126. M. Tsutsui J. Atheroscler. Thromb. 11 2004 41 48
127. S. Yamada, K.Y. Wang, A. Tanimoto, J. Fan, S. Shimajiri, S. Kitajima, M. Morimoto, M. Tsutsui, T. Watanabe, K. Yasumoto, and Y. Sasaguri Am. J. Pathol. 172 2008 1419 1429
128. L.N. Zhang, D.W. Wilson, V. da Cunha, M.E. Sullivan, R. Vergona, J.C. Rutledge, and Y.X. Wang Arterioscler. Thromb. Vasc. Biol. 26 2006 765 772
129. A.P. Sawchuk, J.L. Unthank, T.E. Davis, and M.C. Dalsing J. Vasc. Surg. 19 1994 58 63 (discussion 63-54)
130. J.M. Tarbell, Z.D. Shi, J. Dunn, and H. Jo Annu. Rev. Fluid Mech. 46 2014 591 614
131. S. Chien Am. J. Physiol. Heart Circ. Physiol. 292 2007 H1209 H1224
132. P.F. Davies Arterioscler. Thromb. Vasc. Biol. 22 2002 1755 1757
133. M.L. Chrétien, M. Zhang, M.R. Jackson, A. Kapus, and B.L. Langille J. Cell. Physiol. 224 2010 352 361
134. M. Osawa, M. Masuda, N. Harada, R.B. Lopes, and K. Fujiwara Eur. J. Cell Biol. 72 1997 229 237
135. M. Osawa, M. Masuda, K. Kusano, and K. Fujiwara J. Cell Biol. 158 2002 773 785
136. E. Tzima, M.A. del Pozo, S.J. Shattil, S. Chien, M.A. Schwartz, Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment, 2001.
137. E. Tzima, M. Irani-Tehrani, W.B. Kiosses, E. Dejana, D.A. Schultz, B. Engelhardt, G. Cao, H. DeLisser, and M.A. Schwartz Nature 437 2005 426 431
138. A.R. Pries, T.W. Secomb, and P. Gaehtgens Pflugers Arch. 440 2000 653 666
139. R.H. Adamson, and G. Clough J. Physiol. 445 1992 473 486
140. A. Koo, C.F. Dewey Jr., and G. Garcia-Cardena Am. J. Physiol. Cell Physiol. 304 2013 C137 C146
141. N.S. Ihrcke, and J.L. Platt J. Cell Physiol. 168 1996 625 637
142. M.M. Fuster, and L. Wang Prog. Mol. Biol. Transl. Sci. 93 2010 179 212
143. D.R. Coombe, and W.C. Kett Cell. Mol. Life Sci. 62 2005 410 424
144. R.E. Hileman, J.R. Fromm, J.M. Weiler, and R.J. Linhardt Bioessays 20 1998 156 167
145. E.M. Munoz, and R.J. Linhardt Arterioscler. Thromb. Vasc. Biol. 24 2004 1549 1557
146. R.L. Jackson, S.J. Busch, and A.D. Cardin Physiol. Rev. 71 1991 481 539
147. J.A. Florian, J.R. Kosky, K. Ainslie, Z. Pang, R.O. Dull, and J.M. Tarbell Circ. Res. 93 2003 e136 142
148. M. Hecker, A. Mulsch, E. Bassenge, and R. Busse Am. J. Physiol. 265 1993 H828 H833
149. S. Mochizuki, H. Vink, O. Hiramatsu, T. Kajita, F. Shigeto, J.A. Spaan, and F. Kajiya Am. J. Physiol. Heart Circ. Physiol. 285 2003 H722 H726
150. J.J. Moon, M. Matsumoto, S. Patel, L. Lee, J.L. Guan, and S. Li J. Cell. Physiol. 203 2005 166 176
151. M.M. Thi, J.M. Tarbell, S. Weinbaum, and D.C. Spray Proc. Natl. Acad. Sci. U. S. A. 101 2004 16483 16488
152. M. Bernfield, M. Gotte, P.W. Park, O. Reizes, M.L. Fitzgerald, J. Lincecum, and M. Zako Annu. Rev. Biochem. 68 1999 729 777
153. V. Rizzo, C. Morton, N. DePaola, J.E. Schnitzer, and P.F. Davies Am. J. Physiol. Heart Circ. Physiol. 285 2003 H1720 H1729
154. Y. Li, J. Ouyang, H. Zheng, Z. Yu, and B. Wang Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 22 2005 1020 1023
155. J.L. Balligand, O. Feron, and C. Dessy Physiol. Rev. 89 2009 481 534
156. J.F. Arnal, A.T. Dinh-Xuan, M. Pueyo, B. Darblade, and J. Rami Cell. Mol. Life Sci. 55 1999 1078 1087
157. B. Yang, and V. Rizzo Cell. Mol. Bioeng. 6 2013 346 354
158. E. Tkachenko, J.M. Rhodes, and M. Simons Circ. Res. 96 2005 488 500
159. A. Yoneda, and J.R. Couchman Matrix Biol. 22 2003 25 33
160. J. Yoo, M.J. Jeong, H.J. Cho, E.S. Oh, and M.Y. Han Biochem. Biophys. Res. Commun. 328 2005 424 431
161. J.J. Essner, E. Chen, and S.C. Ekker Int. J. Biochem. Cell Biol. 38 2006 152 156
162. M. Simons, and A. Horowitz Cell. Signal. 13 2001 855 862
163. P. Zimmermann, and G. David FASEB J. 13 Suppl. l 1999 S91 S100
164. P.W. Park, O. Reizes, and M. Bernfield J. Biol. Chem. 275 2000 29923 29926
165. B. Rost J. Struct. Biol. 134 2001 204 218
166. K. Lin, V.A. Simossis, W.R. Taylor, and J. Heringa Bioinformatics 21 2005 152 159
167. R.L. Juliano, and S. Haskill J. Cell Biol. 120 1993 577 585
168. M.A. Schwartz, M.D. Schaller, and M.H. Ginsberg Annu. Rev. Cell Dev. Biol. 11 1995 549 599
169. R.O. Hynes Cell 69 1992 11 25
170. R.O. Hynes Cell 110 2002 673 687
171. R.O. Hynes Nat. Med. 8 2002 918 921
172. J.C. Loftus, and R.C. Liddington J. Clin. Investig. 99 1997 2302 2306
173. M.J. Humphries, and P. Newham Trends Cell Biol. 8 1998 78 83
174. S. Jalali, M.A. del Pozo, K.-D. Chen, H. Miao, Y.-S. Li, M.A. Schwartz, J.Y.-J. Shyy, and S. Chien Proc. Natl. Acad. Sci. U. S. A. 98 2001 1042 1046
175. S. Liu, D.A. Calderwood, and M.H. Ginsberg J. Cell Sci. 113 Pt 20 2000 3563 3571
176. S.K. Verma, H. Lal, H.B. Golden, F. Gerilechaogetu, M. Smith, R.S. Guleria, D.M. Foster, G. Lu, and D.E. Dostal Cardiovasc. Res. 90 2011 88 96
177. H. Lal, S.K. Verma, M. Smith, R.S. Guleria, G. Lu, D.M. Foster, and D.E. Dostal J. Mol. Cell. Cardiol. 43 2007 137 147
178. C. Urbich, E. Dernbach, A. Reissner, M. Vasa, A.M. Zeiher, and S. Dimmeler Arterioscler. Thromb. Vasc. Biol. 22 2002 69 75
179. E. Chavakis, A. Aicher, C. Heeschen, K. Sasaki, R. Kaiser, N. El Makhfi, C. Urbich, T. Peters, K. Scharffetter-Kochanek, A.M. Zeiher, T. Chavakis, and S. Dimmeler J. Exp. Med. 201 2005 63 72
180. J.R. Sims, S. Karp, and D.E. Ingber J. Cell Sci. 103 Pt 4 1992 1215 1222
181. A.J. Maniotis, C.S. Chen, and D.E. Ingber Proc. Natl. Acad. Sci. U. S. A. 94 1997 849 854
182. N. Wang, I.M. Tolic-Norrelykke, J. Chen, S.M. Mijailovich, J.P. Butler, J.J. Fredberg, and D. Stamenovic Am. J. Physiol. Cell Physiol. 282 2002 C606 C616
183. D. Stamenovic, S.M. Mijailovich, I.M. Tolic-Norrelykke, J. Chen, and N. Wang Am. J. Physiol. Cell Physiol. 282 2002 C617 C624
184. N. Wang, K. Naruse, D. Stamenovic, J.J. Fredberg, S.M. Mijailovich, I.M. Tolic-Norrelykke, T. Polte, R. Mannix, and D.E. Ingber Proc. Natl. Acad. Sci. U. S. A. 98 2001 7765 7770
185. D.E. Ingber J. Cell Sci. 116 2003 1157 1173
186. C.S. Chen, and D.E. Ingber Osteoarthr. Cartil. 7 1999 81 94
187. D.E. Ingber Annu. Rev. Physiol. 59 1997 575 599
188. Y.C. Poh, S.P. Shevtsov, F. Chowdhury, D.C. Wu, S. Na, M. Dundr, and N. Wang Nat. Commun. 3 2012 866
189. J.D. Pajerowski, K.N. Dahl, F.L. Zhong, P.J. Sammak, and D.E. Discher Proc. Natl. Acad. Sci. U. S. A. 104 2007 15619 15624
190. J. Lammerding, P.C. Schulze, T. Takahashi, S. Kozlov, T. Sullivan, R.D. Kamm, C.L. Stewart, and R.T. Lee J. Clin. Investig. 113 2004 370 378
191. J. Lammerding, L.G. Fong, J.Y. Ji, K. Reue, C.L. Stewart, S.G. Young, and R.T. Lee J. Biol. Chem. 281 2006 25768 25780
192. J. Lammerding, and R.T. Lee Methods Mol. Biol. 464 2009 13 26
193. M.L. Lombardi, D.E. Jaalouk, C.M. Shanahan, B. Burke, K.J. Roux, and J. Lammerding J. Biol. Chem. 286 2011 26743 26753
194. F. Guilak J. Biomech. 28 1995 1529 1541
195. F. Guilak, J.R. Tedrow, and R. Burgkart Biochem. Biophys. Res. Commun. 269 2000 781 786
196. H.F. Horn, Z. Brownstein, D.R. Lenz, S. Shivatzki, A.A. Dror, O. Dagan-Rosenfeld, L.M. Friedman, K.J. Roux, S. Kozlov, K.T. Jeang, M. Frydman, B. Burke, C.L. Stewart, and K.B. Avraham J. Clin. Investig. 123 2013 740 750
197. W. Wang, Z. Shi, S. Jiao, C. Chen, H. Wang, G. Liu, Q. Wang, Y. Zhao, M.I. Greene, and Z. Zhou Cell Res. 22 2012 1440 1452
198. D.N. Simon, and K.L. Wilson Nat. Rev. Mol. Cell Biol. 12 2011 695 708
199. D.A. Starr, and H.N. Fridolfsson Annu. Rev. Cell Dev. Biol. 26 2010 421 444
200. M. Crisp, Q. Liu, K. Roux, J.B. Rattner, C. Shanahan, B. Burke, P.D. Stahl, and D. Hodzic J. Cell Biol. 172 2006 41 53
201. B. Burke, and K.J. Roux Dev. Cell 17 2009 587 597
202. N. Wang, J.D. Tytell, and D.E. Ingber Nat. Rev. Mol. Cell Biol. 10 2009 75 82
203. C.Y. Ho, and J. Lammerding J. Cell Sci. 125 2012 2087 2093
204. E. Tkachenko, E. Gutierrez, S.K. Saikin, P. Fogelstrand, C. Kim, A. Groisman, and M.H. Ginsberg Biol. Open 2 2013 1007 1012
205. J.T. Morgan, J.A. Wood, N.M. Shah, M.L. Hughbanks, P. Russell, A.I. Barakat, and C.J. Murphy Biomaterials 33 2012 4126 4135
206. B.S. Dragt, E.L. van Agtmaal, B. de Laat, and J. Voorberg Thromb. Res. 130 2012 741 745
207. G.R. Fedorchak, A. Kaminski, and J. Lammerding Prog. Biophys. Mol. Biol. 115 2014 76 92
208. B. Zimmerman, A. Beautrait, B. Aguila, R. Charles, E. Escher, A. Claing, M. Bouvier, and S.A. Laporte Sci. Signal. 5 2012 ra33
209. P.K. Mehta, and K.K. Griendling Am. J. Physiol. Cell Physiol. 292 2007 C82 C97
210. J. Yatabe, H. Sanada, M.S. Yatabe, S. Hashimoto, M. Yoneda, R.A. Felder, P.A. Jose, and T. Watanabe Am. J. Physiol. Ren. Physiol. 296 2009 F1052 F1060
211. Y. Zou, H. Akazawa, Y. Qin, M. Sano, H. Takano, T. Minamino, N. Makita, K. Iwanaga, W. Zhu, S. Kudoh, H. Toko, K. Tamura, M. Kihara, T. Nagai, A. Fukamizu, S. Umemura, T. Iiri, T. Fujita, and I. Komuro Nat. Cell Biol. 6 2004 499 506
212. N. Yasuda, H. Akazawa, Y. Qin, Y. Zou, and I. Komuro Naunyn Schmiedeb. Arch. Pharmacol. 377 2008 393 399
213. U. Storch, M. Mederos y Schnitzler, and T. Gudermann Am. J. Physiol. Heart Circ. Physiol. 302 2012 H1241 H1249
214. K. Rakesh, B. Yoo, I.M. Kim, N. Salazar, K.S. Kim, and H.A. Rockman Sci. Signal. 3 2010 ra46
215. M. Mederos y Schnitzler, U. Storch, and T. Gudermann Curr. Opin. Pharmacol. 11 2011 112 116
216. Y.S. Chatzizisis, A.U. Coskun, M. Jonas, E.R. Edelman, C.L. Feldman, and P.H. Stone J. Am. Coll. Cardiol. 49 2007 2379 2393
217. O. Traub, B. Hertlein, M. Kasper, R. Eckert, A. Krisciukaitis, D. Hulser, and K. Willecke Eur. J. Cell Biol. 77 1998 313 322
218. J. Hwang, M.H. Ing, A. Salazar, B. Lassegue, K. Griendling, M. Navab, A. Sevanian, and T.K. Hsiai Circ. Res. 93 2003 1225 1232
219. J.Y. Shyy, and S. Chien Circ. Res. 91 2002 769 775
220. Y. Liu, B.P. Chen, M. Lu, Y. Zhu, M.B. Stemerman, S. Chien, and J.Y. Shyy Arterioscler. Thromb. Vasc. Biol. 22 2002 76 81
221. J.N. Topper, J. Cai, D. Falb, and M.A. Gimbrone Jr. Proc. Natl. Acad. Sci. U. S. A. 93 1996 10417 10422
222. N. Wang, H. Miao, Y.S. Li, P. Zhang, J.H. Haga, Y. Hu, A. Young, S. Yuan, P. Nguyen, C.C. Wu, and S. Chien Biochem. Biophys. Res. Commun. 341 2006 1244 1251
223. W. Takabe, E. Warabi, and N. Noguchi Antioxid. Redox Signal 15 2011 1415 1426
224. S. Dimmeler, and A.M. Zeiher Cell Death Differ. 6 1999 964 968
225. S. Dimmeler, I. Fleming, B. Fisslthaler, C. Hermann, R. Busse, and A.M. Zeiher Nature 399 1999 601 605
226. M. Hecker, I. Fleming, and R. Busse Agents Actions Suppl. 45 1995 119 127
227. L. Nayak, Z. Lin, and M.K. Jain Antioxid. Redox Signal 15 2011 1449 1461
228. R.J. Dekker, S. van Soest, R.D. Fontijn, S. Salamanca, P.G. de Groot, E. VanBavel, H. Pannekoek, A.J.G. Horrevoets, Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2), 2002.
229. H. Das, A. Kumar, Z. Lin, W.D. Patino, P.M. Hwang, M.W. Feinberg, P.K. Majumder, and M.K. Jain Proc. Natl. Acad. Sci. U. S. A. 103 2006 6653 6658
230. Z. Lin, A. Hamik, R. Jain, A. Kumar, and M.K. Jain Arterioscler. Thromb. Vasc. Biol. 26 2006 1185 1189
231. S. SenBanerjee, Z. Lin, G.B. Atkins, D.M. Greif, R.M. Rao, A. Kumar, M.W. Feinberg, Z. Chen, D.I. Simon, F.W. Luscinskas, T.M. Michel, M.A. Gimbrone Jr., G. Garcia-Cardena, and M.K. Jain J. Exp. Med. 199 2004 1305 1315
232. J.O. Fledderus, R.A. Boon, O.L. Volger, H. Hurttila, S. Yla-Herttuala, H. Pannekoek, A.L. Levonen, and A.J. Horrevoets Arterioscler. Thromb. Vasc. Biol. 28 2008 1339 1346
233. R.A. Boon, T.A. Leyen, R.D. Fontijn, J.O. Fledderus, J.M. Baggen, O.L. Volger, G.P. van Nieuw Amerongen, and A.J. Horrevoets Blood 115 2010 2533 2542
234. B. Razani, J.A. Engelman, X.B. Wang, W. Schubert, X.L. Zhang, C.B. Marks, F. Macaluso, R.G. Russell, M. Li, R.G. Pestell, D. Di Vizio, H. Hou Jr., B. Kneitz, G. Lagaud, G.J. Christ, W. Edelmann, and M.P. Lisanti J. Biol. Chem. 276 2001 38121 38138
235. B.L. Goodwin, L.P. Solomonson, and D.C. Eichler J. Biol. Chem. 279 2004 18353 18360
236. R.J. Dekker, J.V. van Thienen, J. Rohlena, S.C. de Jager, Y.W. Elderkamp, J. Seppen, C.J. de Vries, E.A. Biessen, T.J. van Berkel, H. Pannekoek, and A.J. Horrevoets Am. J. Pathol. 167 2005 609 618
237. R.J. Dekker, R.A. Boon, M.G. Rondaij, A. Kragt, O.L. Volger, Y.W. Elderkamp, J.C. Meijers, J. Voorberg, H. Pannekoek, and A.J. Horrevoets Blood 107 2006 4354 4363
238. R.A. Boon, J.O. Fledderus, O.L. Volger, E.J. van Wanrooij, E. Pardali, F. Weesie, J. Kuiper, H. Pannekoek, P. ten Dijke, and A.J. Horrevoets Arterioscler. Thromb. Vasc. Biol. 27 2007 532 539
239. R. Bhattacharya, S. Senbanerjee, Z. Lin, S. Mir, A. Hamik, P. Wang, P. Mukherjee, D. Mukhopadhyay, and M.K. Jain J. Biol. Chem. 280 2005 28848 28851
240. K.M. Parmar, H.B. Larman, G. Dai, Y. Zhang, E.T. Wang, S.N. Moorthy, J.R. Kratz, Z. Lin, M.K. Jain, M.A. Gimbrone Jr., and G. Garcia-Cardena J. Clin. Investig. 116 2006 49 58
241. W. Wang, C.H. Ha, B.S. Jhun, C. Wong, M.K. Jain, and Z.G. Jin Blood 115 2010 2971 2979
242. J.V. van Thienen, J.O. Fledderus, R.J. Dekker, J. Rohlena, G.A. van Ijzendoorn, N.A. Kootstra, H. Pannekoek, and A.J. Horrevoets Cardiovasc. Res. 72 2006 231 240
243. W.J. Rhee, C.W. Ni, Z. Zheng, K. Chang, H. Jo, and G. Bao Proc. Natl. Acad. Sci. U. S. A. 107 2010 6858 6863
244. A. Kumar, Z. Lin, S. SenBanerjee, and M.K. Jain Mol. Cell. Biol. 25 2005 5893 5903
245. C.H. Woo, T. Shishido, C. McClain, J.H. Lim, J.D. Li, J. Yang, C. Yan, and J. Abe Circ. Res. 102 2008 538 545
246. A. Kumar, T.A. Hoffman, J. Dericco, A. Naqvi, M.K. Jain, and K. Irani FASEB J. 23 2009 4344 4352
247. T. Yoshida, K.H. Kaestner, and G.K. Owens Circ. Res. 102 2008 1548 1557
248. N. Duerrschmidt, C. Stielow, G. Muller, P.J. Pagano, and H. Morawietz J. Physiol. 576 2006 557 567
249. W. Doehner, N. Schoene, M. Rauchhaus, F. Leyva-Leon, D.V. Pavitt, D.A. Reaveley, G. Schuler, A.J. Coats, S.D. Anker, and R. Hambrecht Circulation 105 2002 2619 2624
250. S. Kumar, N. Sud, F.V. Fonseca, Y. Hou, and S.M. Black Am. J. Physiol. Lung Cell. Mol. Physiol. 298 2010 L105 L116
251. N. Kang-Decker, S. Cao, S. Chatterjee, J. Yao, L.J. Egan, D. Semela, D. Mukhopadhyay, and V. Shah J. Cell Sci. 120 2007 492 501
252. J.S. McNally, M.E. Davis, D.P. Giddens, A. Saha, J. Hwang, S. Dikalov, H. Jo, and D.G. Harrison Am. J. Physiol. Heart Circ. Physiol. 285 2003 H2290 H2297
253. T. Ziegler, P. Silacci, V.J. Harrison, and D. Hayoz Hypertension 32 1998 351 355
254. Z. Xiao, Z. Zhang, V. Ranjan, and S.L. Diamond J. Cell Physiol. 171 1997 205 211
255. E.M. Redmond, P.A. Cahill, and J.V. Sitzmann Arterioscler. Thromb. Vasc. Biol. 18 1998 75 83
256. N. Hori, R. Wiest, and R.J. Groszmann Hepatology (Baltimore, Md.) 28 1998 1467 1473
257. L.M. Villa, E. Salas, V.M. Darley-Usmar, M.W. Radomski, and S. Moncada Proc. Natl. Acad. Sci. U. S. A. 91 1994 12383 12387
258. C.L. Hartsfield, J. Alam, J.L. Cook, and A.M. Choi Am. J. Physiol. 273 1997 L980 L988
259. A. Bouloumie, J. Bauersachs, W. Linz, B.A. Scholkens, G. Wiemer, I. Fleming, and R. Busse Hypertension 30 1997 934 941
260. B. Zingarelli, G. Hasko, A.L. Salzman, and C. Szabo Crit. Care Med. 27 1999 1701 1707
261. J.M. Li, and A.M. Shah Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 2004 R1014 R1030
262. B. Kalyanaraman, V. Darley-Usmar, K.J. Davies, P.A. Dennery, H.J. Forman, M.B. Grisham, G.E. Mann, K. Moore, L.J. Roberts II, and H. Ischiropoulos Free Radic. Biol. Med. 52 2012 1 6
263. A. Alfieri, S. Srivastava, R.C. Siow, D. Cash, M. Modo, M.R. Duchen, P.A. Fraser, S.C. Williams, and G.E. Mann Free Radic. Biol. Med. 65 2013 1012 1022
264. P.S. Tsao, N.P. Lewis, S. Alpert, and J.P. Cooke Circulation 92 1995 3513 3519
265. M. Noris, M. Morigi, R. Donadelli, S. Aiello, M. Foppolo, M. Todeschini, S. Orisio, G. Remuzzi, and A. Remuzzi Circ. Res. 76 1995 536 543
266. J. Hwang, A. Saha, Y.C. Boo, G.P. Sorescu, J.S. McNally, S.M. Holland, S. Dikalov, D.P. Giddens, K.K. Griendling, D.G. Harrison, and H. Jo J. Biol. Chem. 278 2003 47291 47298
267. J.G. Dickhout, G.S. Hossain, L.M. Pozza, J. Zhou, S. Lhotak, and R.C. Austin Arterioscler. Thromb. Vasc. Biol. 25 2005 2623 2629
268. D.C. Chappell, S.E. Varner, R.M. Nerem, R.M. Medford, and R.W. Alexander Circ. Res. 82 1998 532 539
269. A.R. Brooks, P.I. Lelkes, and G.M. Rubanyi Physiol. Genomics 9 2002 27 41
270. P. Silacci, K. Formentin, K. Bouzourene, F. Daniel, H.R. Brunner, and D. Hayoz Nitric Oxide 4 2000 47 56
271. T.K. Hsiai, J. Hwang, M.L. Barr, A. Correa, R. Hamilton, M. Alavi, M. Rouhanizadeh, E. Cadenas, and S.L. Hazen Free Radic. Biol. Med. 42 2007 519 529
272. L. Ai, M. Rouhanizadeh, J.C. Wu, W. Takabe, H. Yu, M. Alavi, R. Li, Y. Chu, J. Miller, D.D. Heistad, and T.K. Hsiai Am. J. Physiol. Cell Physiol. 294 2008 C1576 C1585
273. K.S. Cunningham, and A.I. Gotlieb Lab. Investig. 85 2005 9 23
274. E. Warabi, W. Takabe, T. Minami, K. Inoue, K. Itoh, M. Yamamoto, T. Ishii, T. Kodama, and N. Noguchi Free Radic. Biol. Med. 42 2007 260 269
275. C.Y. Hsieh, H.Y. Hsiao, W.Y. Wu, C.A. Liu, Y.C. Tsai, Y.J. Chao, D.L. Wang, and H.J. Hsieh J. Biomed. Sci. 16 2009 12
276. M. Okouchi, N. Okayama, J.S. Alexander, and T.Y. Aw Curr. Neurovasc. Res. 3 2006 249 261
277. N. Acar, H. Soylu, I. Edizer, O. Ozbey, H. Er, G. Akkoyunlu, B. Gemici, and I. Ustunel Acta Histochem. 116 2014 1289 1300
278. Y. Zhang, D.H. Crouch, M. Yamamoto, and J.D. Hayes Biochem. J. 399 2006 373 385
279. S.M. Meadows, M.C. Salanga, and P.A. Krieg Development (Cambridge, England) 136 2009 1115 1125
280. J. Wu, C.S. Bohanan, J.C. Neumann, and J.B. Lingrel J. Biol. Chem. 283 2008 3942 3950
281. C. Knorr-Wittmann, A. Hengstermann, S. Gebel, J. Alam, and T. Muller Free Radic. Biol. Med. 39 2005 1438 1448
282. K. Kataoka, H. Handa, and M. Nishizawa J. Biol. Chem. 276 2001 34074 34081
283. X.L. Chen, S.E. Varner, A.S. Rao, J.Y. Grey, S. Thomas, C.K. Cook, M.A. Wasserman, R.M. Medford, A.K. Jaiswal, and C. Kunsch J. Biol. Chem. 278 2003 703 711
284. G. Dai, S. Vaughn, Y. Zhang, E.T. Wang, G. Garcia-Cardena, and M.A. Gimbrone Jr. Circ. Res. 101 2007 723 733
285. Z. Han, Y.R. Chen, C.I. Jones III, G. Meenakshisundaram, J.L. Zweier, and B.R. Alevriadou Am. J. Physiol. Cell Physiol. 292 2007 C1103 C1112
286. T. Hosoya, A. Maruyama, M.I. Kang, Y. Kawatani, T. Shibata, K. Uchida, E. Warabi, N. Noguchi, K. Itoh, and M. Yamamoto J. Biol. Chem. 280 2005 27244 27250
287. C.I. Jones III, H. Zhu, S.F. Martin, Z. Han, Y. Li, and B.R. Alevriadou Ann. Biomed. Eng. 35 2007 683 693
288. T. Nagel, N. Resnick, W.J. Atkinson, C.F. Dewey Jr., and M.A. Gimbrone Jr. J. Clin. Investig. 94 1994 885 891
289. W.J. Rhee, P.J. Santangelo, H. Jo, and G. Bao Nucleic Acids Res. 36 2008 e30
290. Z. Zhou, Y. Liu, A.D. Miao, and S.Q. Wang Eur. J. Pharmacol. 513 2005 1 8
291. H. Ueno, S. Pradhan, D. Schlessel, H. Hirasawa, and B.E. Sumpio Cardiovasc. Toxicol. 6 2006 39 50
292. S.J. Lin, S.K. Shyue, Y.Y. Hung, Y.H. Chen, H.H. Ku, J.W. Chen, K.B. Tam, and Y.L. Chen Arterioscler. Thromb. Vasc. Biol. 25 2005 334 340
293. H. Ishii, and K. Takada Toxicol. Appl. Pharmacol. 184 2002 88 97
294. A.K. Hubbard, and R. Rothlein Free Radic. Biol. Med. 28 2000 1379 1386
295. H. Fan, B. Sun, Q. Gu, A. Lafond-Walker, S. Cao, and L.C. Becker Am. J. Physiol. Heart Circ. Physiol. 282 2002 H1778 H1786
296. Y. Suzuki, W. Wang, T.H. Vu, and T.A. Raffin Biochem. Biophys. Res. Commun. 184 1992 1339 1343
297. C. Weber, W. Erl, A. Pietsch, M. Strobel, H.W. Ziegler-Heitbrock, and P.C. Weber Arterioscler. Thromb. 14 1994 1665 1673
298. J.A. Holland, J.W. Meyer, M.E. Schmitt, M.D. Sauro, D.K. Johnson, R.W. Abdul-Karim, V. Patel, L.M. Ziegler, K.J. Schillinger, R.F. Small, and L.F. Lemanski Endothelium 5 1997 191 207
299. L.M. Khachigian, N. Resnick, M.A. Gimbrone Jr., and T. Collins J. Clin. Investig. 96 1995 1169 1175
300. Q. Lan, K.O. Mercurius, and P.F. Davies Biochem. Biophys. Res. Commun. 201 1994 950 956
301. D. Sorescu, D. Weiss, B. Lassegue, R.E. Clempus, K. Szocs, G.P. Sorescu, L. Valppu, M.T. Quinn, J.D. Lambeth, J.D. Vega, W.R. Taylor, and K.K. Griendling Circulation 105 2002 1429 1435
302. C.R. Woodman, J.M. Muller, J.W. Rush, M.H. Laughlin, and E.M. Price Am. J. Physiol. 276 1999 H1058 H1063
303. M. Nazari-Jahantigh, Y. Wei, and A. Schober Thromb. Haemost. 107 2012 611 618
304. R.A. Cohen, and P.M. Vanhoutte Circulation 92 1995 3337 3349
305. T.J. Lee, and J.G. Yu Ann. N. Y. Acad. Sci. 962 2002 73 80
306. S.L. Archer, F.S. Gragasin, X. Wu, S. Wang, S. McMurtry, D.H. Kim, M. Platonov, A. Koshal, K. Hashimoto, W.B. Campbell, J.R. Falck, and E.D. Michelakis Circulation 107 2003 769 776
307. S.S. Bolz, C. de Wit, and U. Pohl Br. J. Pharmacol. 128 1999 124 134
308. Y. Hayabuchi, Y. Nakaya, S. Matsuoka, and Y. Kuroda J. Cardiovasc. Pharmacol. 32 1998 642 649
309. D.A. Chistiakov, A.N. Orekhov, and Y.V. Bobryshev Cell. Mol. Life Sci. 72 2015 2697 2708
310. J. Zhou, Y.S. Li, P. Nguyen, K.C. Wang, A. Weiss, Y.C. Kuo, J.J. Chiu, J.Y. Shyy, and S. Chien Circ. Res. 113 2013 40 51
311. S. Wang, A.B. Aurora, B.A. Johnson, X. Qi, J. McAnally, J.A. Hill, J.A. Richardson, R. Bassel-Duby, and E.N. Olson Dev. Cell 15 2008 261 271
312. Y. Fang, C. Shi, E. Manduchi, M. Civelek, and P.F. Davies Proc. Natl. Acad. Sci. U. S. A. 107 2010 13450 13455
313. X. Qin, X. Wang, Y. Wang, Z. Tang, Q. Cui, J. Xi, Y.S. Li, S. Chien, and N. Wang Proc. Natl. Acad. Sci. U. S. A. 107 2010 3240 3244
314. Y. Fang, and P.F. Davies Arterioscler. Thromb. Vasc. Biol. 32 2012 979 987
315. L.J. Chen, L. Chuang, Y.H. Huang, J. Zhou, S.H. Lim, C.I. Lee, W.W. Lin, T.E. Lin, W.L. Wang, L. Chen, S. Chien, and J.J. Chiu Circ. Res. 116 2015 1157 1169
316. Z. Chen, L. Wen, M. Martin, C.Y. Hsu, L. Fang, F.M. Lin, T.Y. Lin, M.J. Geary, G.G. Geary, Y. Zhao, D.A. Johnson, J.W. Chen, S.J. Lin, S. Chien, H.D. Huang, Y.I. Miller, P.H. Huang, and J.Y. Shyy Circulation 131 2015 805 814
317. K.C. Wang, P. Nguyen, A. Weiss, Y.T. Yeh, H.S. Chien, A. Lee, D. Teng, S. Subramaniam, Y.S. Li, and S. Chien Arterioscler. Thromb. Vasc. Biol. 34 2014 1437 1445
318. W. Wu, H. Xiao, A. Laguna-Fernandez, G. Villarreal Jr., K.C. Wang, G.G. Geary, Y. Zhang, W.C. Wang, H.D. Huang, J. Zhou, Y.S. Li, S. Chien, G. Garcia-Cardena, and J.Y. Shyy Circulation 124 2011 633 641
319. J. Zhou, K.C. Wang, W. Wu, S. Subramaniam, J.Y. Shyy, J.J. Chiu, J.Y. Li, and S. Chien Proc. Natl. Acad. Sci. U. S. A. 108 2011 10355 10360
320. K.C. Wang, L.X. Garmire, A. Young, P. Nguyen, A. Trinh, S. Subramaniam, N. Wang, J.Y. Shyy, Y.S. Li, and S. Chien Proc. Natl. Acad. Sci. U. S. A. 107 2010 3234 3239
321. E. Hergenreider, S. Heydt, K. Treguer, T. Boettger, A.J. Horrevoets, A.M. Zeiher, M.P. Scheffer, A.S. Frangakis, X. Yin, M. Mayr, T. Braun, C. Urbich, R.A. Boon, and S. Dimmeler Nat. Cell Biol. 14 2012 249 256
322. K.D. Robertson Oncogene 21 2002 5361 5379
323. K. Mason, Z. Liu, T. Aguirre-Lavin, and N. Beaujean Animal Reprod. Sci. 134 2012 45 55
324. J. Dunn, R. Simmons, S. Thabet, and H. Jo Int. J. Biochem. Cell Biol. 67 2015 Oct 167 176 10.1016/j.biocel.2015.05.001 Epub 2015 May 13
325. G. Lund, L. Andersson, M. Lauria, M. Lindholm, M.F. Fraga, A. Villar-Garea, E. Ballestar, M. Esteller, and S. Zaina J. Biol. Chem. 279 2004 29147 29154
326. A. Baccarelli, M. Rienstra, and E.J. Benjamin Circ. Cardiovasc. Genet. 3 2010 567 573
327. M.P. Turunen, E. Aavik, and S. Yla-Herttuala Biochim. Biophys. Acta 1790 2009 886 891
328. S. Zaina, H. Heyn, F.J. Carmona, N. Varol, S. Sayols, E. Condom, J. Ramirez-Ruz, A. Gomez, I. Goncalves, S. Moran, and M. Esteller Circ. Cardiovasc. Genet. 7 2014 692 700
329. Y.Z. Jiang, J.M. Jimenez, K. Ou, M.E. McCormick, L.D. Zhang, and P.F. Davies Circ. Res. 115 1 2014 Jun 20 32 43 10.1161/CIRCRESAHA.115.303883 Epub 2014 Apr 22
330. J. Dunn, H. Qiu, S. Kim, D. Jjingo, R. Hoffman, C.W. Kim, I. Jang, D.J. Son, D. Kim, C. Pan, Y. Fan, I.K. Jordan, and H. Jo J. Clin. Investig. 124 2014 3187 3199
331. J. Zhou, Y.S. Li, K.C. Wang, and S. Chien Cell. Mol. Bioeng. 7 2014 218 224
332. A. Hamik, Z. Lin, A. Kumar, M. Balcells, S. Sinha, J. Katz, M.W. Feinberg, R.E. Gerzsten, E.R. Edelman, and M.K. Jain J. Biol. Chem. 282 2007 13769 13779
333. A. Hamik, and M.K. Jain Arterioscler. Thromb. Vasc. Biol. 32 2012 839 840
334. J.P. Huddleson, N. Ahmad, S. Srinivasan, and J.B. Lingrel J. Biol. Chem. 280 2005 23371 23379
335. G. Villarreal Jr., Y. Zhang, H.B. Larman, J. Gracia-Sancho, A. Koo, and G. Garcia-Cardena Biochem. Biophys. Res. Commun. 391 2010 984 989
336. A.P.J.J. Bijnens, E. Lutgens, T. Ayoubi, J. Kuiper, A.J. Horrevoets, and M.J.A.P. Daemen Arterioscler. Thromb. Vasc. Biol. 26 2006 1226 1235
337. S. Cagnin, M. Biscuola, C. Patuzzo, E. Trabetti, A. Pasquali, P. Laveder, G. Faggian, M. Iafrancesco, A. Mazzucco, P.F. Pignatti, and G. Lanfranchi BMC Genomics 10 2009 13
338. J.C. Sluimer, N. Kisters, K.B. Cleutjens, O.L. Volger, A.J. Horrevoets, L.H. van den Akker, A.P. Bijnens, and M.J. Daemen Physiol. Genomics 30 2007 335 341
339. E.A. Ashley, R. Ferrara, J.Y. King, A. Vailaya, A. Kuchinsky, X. He, B. Byers, U. Gerckens, S. Oblin, A. Tsalenko, A. Soito, J.M. Spin, R. Tabibiazar, A.J. Connolly, J.B. Simpson, E. Grube, and T. Quertermous Circulation 114 2006 2644 2654
340. R. Tabibiazar, R.A. Wagner, E.A. Ashley, J.Y. King, R. Ferrara, J.M. Spin, D.A. Sanan, B. Narasimhan, R. Tibshirani, P.S. Tsao, B. Efron, and T. Quertermous Physiol. Genomics 22 2005 213 226
341. J. Skogsberg, J. Lundstrom, A. Kovacs, R. Nilsson, P. Noori, S. Maleki, M. Kohler, A. Hamsten, J. Tegner, and J. Bjorkegren PLoS Genet. 4 2008 e1000036
342. V.M. Herrera, T. Didishvili, L.V. Lopez, and N. Ruiz-Opazo Mol. Med. 8 2002 367 375
343. R.L. Geary, J.M. Wong, A. Rossini, S.M. Schwartz, and L.D. Adams Arterioscler. Thromb. Vasc. Biol. 22 2002 2010 2016
344. M. Civelek, E. Manduchi, R.J. Riley, C.J. Stoeckert Jr., and P.F. Davies Circ. Cardiovasc. Genet. 4 2011 243 252
345. Y. Doring, H. Noels, and C. Weber Arterioscler. Thromb. Vasc. Biol. 32 2012 182 195
346. O.L. Volger, J.O. Fledderus, N. Kisters, R.D. Fontijn, P.D. Moerland, J. Kuiper, T.J. van Berkel, A.P. Bijnens, M.J. Daemen, H. Pannekoek, and A.J. Horrevoets Am. J. Pathol. 171 2007 326 337
347. E. Trogan, R.P. Choudhury, H.M. Dansky, J.X. Rong, J.L. Breslow, and E.A. Fisher Proc. Natl. Acad. Sci. U. S. A. 99 2002 2234 2239
348. J. Shalhoub, M.B. Sikkel, K.J. Davies, P.A. Vorkas, E.J. Want, and A.H. Davies Vasc. Endovasc. Surg. 48 2014 5 17
349. S.A. Ramsey, E.S. Gold, and A. Aderem EMBO Mol. Med. 2 2010 79 89
350. A. Ghazalpour, S. Doss, X. Yang, J. Aten, E.M. Toomey, A. Van Nas, S. Wang, T.A. Drake, and A.J. Lusis J. Lipid Res. 45 2004 1793 1805
351. A.P. Bijnens, E. Lutgens, T. Ayoubi, J. Kuiper, A.J. Horrevoets, and M.J. Daemen Arterioscler. Thromb. Vasc. Biol. 26 2006 1226 1235
352. S.M. McCormick, S.G. Eskin, L.V. McIntire, C.L. Teng, C.M. Lu, C.G. Russell, and K.K. Chittur Proc. Natl. Acad. Sci. U. S. A. 98 2001 8955 8960
353. S.M. McCormick, S.R. Frye, S.G. Eskin, C.L. Teng, C.M. Lu, C.G. Russell, K.K. Chittur, and L.V. McIntire Biorheology 40 2003 5 11
354. B.P. Chen, Y.S. Li, Y. Zhao, K.D. Chen, S. Li, J. Lao, S. Yuan, J.Y. Shyy, and S. Chien Physiol. Genomics 7 2001 55 63
355. N. Ohura, K. Yamamoto, S. Ichioka, T. Sokabe, H. Nakatsuka, A. Baba, M. Shibata, T. Nakatsuka, K. Harii, Y. Wada, T. Kohro, T. Kodama, and J. Ando J. Atheroscler. Thromb. 10 2003 304 313
356. C.W. Ni, H. Qiu, A. Rezvan, K. Kwon, D. Nam, D.J. Son, J.E. Visvader, and H. Jo Blood 116 2010 e66 73
357. D.P. Bartel Cell 116 2004 281 297
358. M. Weber, M.B. Baker, J.P. Moore, and C.D. Searles Biochem. Biophys. Res. Commun. 393 2010 643 648
359. C.W. Ni, H. Qiu, and H. Jo Am. J. Physiol. Heart Circ. Physiol. 300 2011 H1762 H1769
360. X. Wang, X. Fang, J. Zhou, Z. Chen, B. Zhao, L. Xiao, A. Liu, Y.S. Li, J.Y. Shyy, Y. Guan, S. Chien, and N. Wang Proc. Natl. Acad. Sci. U. S. A. 110 2013 13174 13179
361. R.D. Shepherd, S.M. Kos, and K.D. Rinker Am. J. Physiol. Heart Circ. Physiol. 301 2011 H98 H107
362. C.M. Potter, M.H. Lundberg, L.S. Harrington, C.M. Warboys, T.D. Warner, R.E. Berson, A.V. Moshkov, J. Gorelik, P.D. Weinberg, and J.A. Mitchell Arterioscler. Thromb. Vasc. Biol. 31 2011 384 391
363. A. Prigent-Tessier, A. Quirie, K. Maguin-Gate, J. Szostak, C. Mossiat, M. Nappey, S. Devaux, C. Marie, and C. Demougeot Cardiovasc. Res. 100 2013 374 382
364. V.G. Barauna, L.C. Campos, A.A. Miyakawa, and J.E. Krieger PLoS One 6 2011 e22803
365. L. Xue, C. Yu, X. Liu, Y. Lai, Y. Zeng, and Y. Zhang Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 24 2007 1054 1057
366. C. Urbich, D.H. Walter, A.M. Zeiher, and S. Dimmeler Circ. Res. 87 2000 683 689
367. A. Soghomonians, T.L. Thirkill, N.F. Mariano, A.I. Barakat, and G.C. Douglas Toxicol. Sci. 81 2004 408 418
368. N. Ozawa, M. Shichiri, M. Iwashina, N. Fukai, T. Yoshimoto, and Y. Hirata Hypertens. Res. 27 2004 93 99
369. E. Eng, and B.J. Ballermann Microvasc. Res. 65 2003 137 144
370. F.A. Kudo, B. Warycha, P.J. Juran, H. Asada, D. Teso, F. Aziz, J. Frattini, B.E. Sumpio, T. Nishibe, C. Cha, and A. Dardik Am. J. Surg. 190 2005 763 769
371. X.L. Wang, A. Fu, S. Raghavakaimal, and H.C. Lee Proteomics 7 2007 588 596
372. M. Cattaruzza, T.J. Guzik, W. Slodowski, A. Pelvan, J. Becker, M. Halle, A.B. Buchwald, K.M. Channon, and M. Hecker Circ. Res. 95 2004 841 847
373. G.P. Rossi, M. Cesari, M. Zanchetta, S. Colonna, G. Maiolino, L. Pedon, M. Cavallin, P. Maiolino, and A.C. Pessina J. Am. Coll. Cardiol. 41 2003 930 937
374. M.G. Colombo, U. Paradossi, M.G. Andreassi, N. Botto, S. Manfredi, S. Masetti, A. Biagini, and A. Clerico Clin. Chem. 49 2003 389 395
375. A.R. Asif, M. Hecker, and M. Cattaruzza Arterioscler. Thromb. Vasc. Biol. 29 2009 1890 1893
376. Z. Chen, I.C. Peng, W. Sun, M.I. Su, P.H. Hsu, Y. Fu, Y. Zhu, K. DeFea, S. Pan, M.D. Tsai, and J.Y. Shyy Circ. Res. 104 2009 496 505
377. B. Gallis, G.L. Corthals, D.R. Goodlett, H. Ueba, F. Kim, S.R. Presnell, D. Figeys, D.G. Harrison, B.C. Berk, R. Aebersold, and M.A. Corson J. Biol. Chem. 274 1999 30101 30108
378. J.M. Hare, and J.S. Stamler Nat. Med. 5 1999 273 274
379. J. Sun, and E. Murphy Circ. Res. 106 2010 285 296
380. J.M. Hare, and J.S. Stamler J. Clin. Investig. 115 2005 509 517
381. N.J. Kettenhofen, X. Wang, M.T. Gladwin, and N. Hogg Methods Enzymol. 441 2008 53 71
382. B. Huang, S.C. Chen, and D.L. Wang Cardiovasc. Res. 83 2009 536 546
383. J.K. Freed, M.R. Shortreed, C.J. Kleefisch, L.M. Smith, and A.S. Greene Endothelium 15 2008 225 230
384. G.D. Thakker, D.P. Hajjar, W.A. Muller, and T.K. Rosengart J. Biol. Chem. 274 1999 10002 10007
385. R.M. Bell, and D.J. Burns J. Biol. Chem. 266 1991 4661 4664
386. L. Wen, Z. Chen, F. Zhang, X. Cui, W. Sun, G.G. Geary, Y. Wang, D.A. Johnson, Y. Zhu, S. Chien, and J.Y. Shyy Proc. Natl. Acad. Sci. U. S. A. 110 2013 E2420 E2427
387. J.K. Freed, and A.S. Greene Microcirculation 17 2010 259 270
388. K. Irani Circ. Res. 87 2000 179 183
389. S. Burghoff, and J. Schrader J. Proteome Res. 10 2011 1160 1169
390. M.O. Platt, R.F. Ankeny, G.P. Shi, D. Weiss, J.D. Vega, W.R. Taylor, and H. Jo Am. J. Physiol. Heart Circ. Physiol. 292 2007 H1479 H1486
391. M.O. Platt, R.F. Ankeny, and H. Jo Arterioscler. Thromb. Vasc. Biol. 26 2006 1784 1790
392. A.L. Mowbray, D.H. Kang, S.G. Rhee, S.W. Kang, and H. Jo J. Biol. Chem. 283 2008 1622 1627
393. A. Csiszar, N. Labinskyy, K.E. Smith, A. Rivera, E.N. Bakker, H. Jo, J. Gardner, Z. Orosz, and Z. Ungvari Arterioscler. Thromb. Vasc. Biol. 27 2007 776 782
394. K. Chang, D. Weiss, J. Suo, J.D. Vega, D. Giddens, W.R. Taylor, and H. Jo Circulation 116 2007 1258 1266
395. N.L. Boyd, H. Park, H. Yi, Y.C. Boo, G.P. Sorescu, M. Sykes, and H. Jo Am. J. Physiol. Heart Circ. Physiol. 285 2003 H1113 H1122
396. J. Takai, A. Santu, H. Zheng, S.D. Koh, M. Ohta, L.M. Filimban, V. Lemaitre, R. Teraoka, H. Jo, and H. Miura Am. J. Physiol. Heart Circ. Physiol. 305 2013 H484 H493
397. J.M. Johnson, T. Yu, F.H. Strobel, and D.P. Jones Analyst 135 2010 2864 2870
398. M. Mayr, Y.L. Chung, U. Mayr, X. Yin, L. Ly, H. Troy, S. Fredericks, Y. Hu, J.R. Griffiths, and Q. Xu Arterioscler. Thromb. Vasc. Biol. 25 2005 2135 2142
399. X. Chen, L. Liu, G. Palacios, J. Gao, N. Zhang, G. Li, J. Lu, T. Song, Y. Zhang, and H. Lv J. Sep. Sci. 33 2010 2776 2783
400. K.K. Cheng, G.M. Benson, D.C. Grimsditch, D.G. Reid, S.C. Connor, and J.L. Griffin Physiol. Genomics 41 2010 224 231
401. Z. Wang, E. Klipfell, B.J. Bennett, R. Koeth, B.S. Levison, B. Dugar, A.E. Feldstein, E.B. Britt, X. Fu, Y.M. Chung, Y. Wu, P. Schauer, J.D. Smith, H. Allayee, W.H. Tang, J.A. DiDonato, A.J. Lusis, and S.L. Hazen Nature 472 2011 57 63
402. Y.M. Go, C.W. Kim, D.I. Walker, D.W. Kang, S. Kumar, M. Orr, K. Uppal, A.A. Quyyumi, H. Jo, and D.P. Jones Am. J. Physiol. Regul. Integr. Comp. Physiol. 308 2015 R62 R72