-
1
-
-
0034085698
-
Endothelial dysfunction, hemodynamic forces, and atherogenesis
-
Gimbrone, M.A., Jr., Topper, J.N., Nagel, T., Anderson, K.R., and Garcia-Cardena, G. 2000. Endothelial dysfunction, hemodynamic forces, and atherogenesis. Ann. N. Y. Acad. Sci. 902:230-239; discussion 239-240.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.902
, pp. 230-239
-
-
Gimbrone Jr., M.A.1
Topper, J.N.2
Nagel, T.3
Anderson, K.R.4
Garcia-Cardena, G.5
-
2
-
-
0031833126
-
Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
-
Traub, O., and Berk, B.C. 1998. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler. Thromb. Vasc. Biol. 18:677-685.
-
(1998)
Arterioscler. Thromb. Vasc. Biol.
, vol.18
, pp. 677-685
-
-
Traub, O.1
Berk, B.C.2
-
3
-
-
0029072762
-
Flow-mediated endothelial mechanotransduction
-
Davies, P.F. 1995. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75:519-560.
-
(1995)
Physiol. Rev.
, vol.75
, pp. 519-560
-
-
Davies, P.F.1
-
4
-
-
6944244066
-
Distinct endothelial phenotypes evoked by arterial wave forms derived from atherosclerosis-susceptible and -resistant regions of human vasculature
-
Dai, G., et al. 2004. Distinct endothelial phenotypes evoked by arterial wave forms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc. Natl. Acad. Sci. U. S. A. 101:14871-14876.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 14871-14876
-
-
Dai, G.1
-
5
-
-
0034884577
-
Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway
-
Buckley, A.F., Kuo, C.T., and Leiden, J.M. 2001. Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. Nat. Immunol. 2:698-704.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 698-704
-
-
Buckley, A.F.1
Kuo, C.T.2
Leiden, J.M.3
-
6
-
-
0030823769
-
LKLF: A transcriptional regulator of singlepositive T cell quiescence and survival
-
Kuo, C.T., Veselits, M.L., and Leiden, J.M. 1997. LKLF: a transcriptional regulator of singlepositive T cell quiescence and survival. Science. 277:1986-1990.
-
(1997)
Science
, vol.277
, pp. 1986-1990
-
-
Kuo, C.T.1
Veselits, M.L.2
Leiden, J.M.3
-
7
-
-
0036721376
-
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2)
-
Dekker, R.J., et al. 2002. Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). Blood. 100:1689-1698.
-
(2002)
Blood
, vol.100
, pp. 1689-1698
-
-
Dekker, R.J.1
-
8
-
-
2542500709
-
KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation
-
SenBanerjee, S., et al. 2004. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. J. Exp. Med. 199:1305-1315.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1305-1315
-
-
SenBanerjee, S.1
-
9
-
-
2142694432
-
Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos
-
Groenendijk, B.C., Hierck, B.P., Gittenberger-De Groot, A.C., and Poelmann, R.E. 2004. Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos. Dev. Dyn. 230:57-68.
-
(2004)
Dev. Dyn.
, vol.230
, pp. 57-68
-
-
Groenendijk, B.C.1
Hierck, B.P.2
Gittenberger-De Groot, A.C.3
Poelmann, R.E.4
-
10
-
-
25144498154
-
Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes
-
Dekker, R.J., et al. 2005. Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes. Am. J. Pathol. 167:609-618.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 609-618
-
-
Dekker, R.J.1
-
11
-
-
12644276397
-
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo
-
Stainier, D.Y., et al. 1996. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development. 123:285-292.
-
(1996)
Development
, vol.123
, pp. 285-292
-
-
Stainier, D.Y.1
-
12
-
-
4544302505
-
Fluid shear stress induces endothelial KLF2 gene expression through a defined promoter region
-
Huddleson, J.P., Srinivasan, S., Ahmad, N., and Lingrel, J.B. 2004. Fluid shear stress induces endothelial KLF2 gene expression through a defined promoter region. Biol. Chem. 385:723-729.
-
(2004)
Biol. Chem.
, vol.385
, pp. 723-729
-
-
Huddleson, J.P.1
Srinivasan, S.2
Ahmad, N.3
Lingrel, J.B.4
-
13
-
-
2442442938
-
Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: A calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT)
-
Pan, F., Ye, Z., Cheng, L., and Liu, J.O. 2004. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). J. Biol. Chem. 279:14477-14480.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14477-14480
-
-
Pan, F.1
Ye, Z.2
Cheng, L.3
Liu, J.O.4
-
14
-
-
2142659374
-
Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure
-
doi:10.1172/JCI200419890
-
Hayashi, M., et al. 2004. Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure. J. Clin. Invest. 113:1138-1148. doi:10.1172/JCI200419890.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1138-1148
-
-
Hayashi, M.1
-
15
-
-
1242320042
-
Big mitogenactivated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis
-
Pi, X., Yan, C., and Berk, B.C. 2004. Big mitogenactivated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ. Res. 94:362-369.
-
(2004)
Circ. Res.
, vol.94
, pp. 362-369
-
-
Pi, X.1
Yan, C.2
Berk, B.C.3
-
16
-
-
0032946293
-
Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium
-
Yan, C., Takahashi, M., Okuda, M., Lee, J.D., and Berk, B.C. 1999. Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium. J. Biol. Chem. 274:143-150.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 143-150
-
-
Yan, C.1
Takahashi, M.2
Okuda, M.3
Lee, J.D.4
Berk, B.C.5
-
17
-
-
20744451022
-
Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function
-
Lin, Z., et al. 2005. Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function. Circ. Res. 96:48-57.
-
(2005)
Circ. Res.
, vol.96
, pp. 48-57
-
-
Lin, Z.1
-
18
-
-
0035967887
-
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature
-
Graef, I.A., Chen, F., Chen, L., Kuo, A., and Crabtree, G.R. 2001. Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell. 105:863-875.
-
(2001)
Cell
, vol.105
, pp. 863-875
-
-
Graef, I.A.1
Chen, F.2
Chen, L.3
Kuo, A.4
Crabtree, G.R.5
-
19
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri, C., et al. 1996. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 87:1171-1180.
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
-
20
-
-
2442618330
-
Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells
-
Goodwin, B.L., Solomonson, L.P., and Eichler, D.C. 2004. Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells. J. Biol. Chem. 279:18353-18360.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18353-18360
-
-
Goodwin, B.L.1
Solomonson, L.P.2
Eichler, D.C.3
-
21
-
-
0346365087
-
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: Genetic and physiological evidence
-
Dayoub, H., et al. 2003. Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation. 108:3042-3047.
-
(2003)
Circulation
, vol.108
, pp. 3042-3047
-
-
Dayoub, H.1
-
22
-
-
0035851197
-
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities
-
Razani, B., et al. 2001. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J. Biol. Chem. 276:38121-38138.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38121-38138
-
-
Razani, B.1
-
23
-
-
0021199320
-
Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells
-
Bevilacqua, M.P., Pober, J.S., Majeau, G.R., Cotran, R.S., and Gimbrone, M.A., Jr. 1984. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J. Exp. Med. 160:618-623.
-
(1984)
J. Exp. Med.
, vol.160
, pp. 618-623
-
-
Bevilacqua, M.P.1
Pober, J.S.2
Majeau, G.R.3
Cotran, R.S.4
Gimbrone Jr., M.A.5
-
24
-
-
0042942985
-
Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells
-
Takeya, H., Gabazza, E.C., Aoki, S., Ueno, H., and Suzuki, K. 2003. Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells. Blood. 102:1693-1700.
-
(2003)
Blood
, vol.102
, pp. 1693-1700
-
-
Takeya, H.1
Gabazza, E.C.2
Aoki, S.3
Ueno, H.4
Suzuki, K.5
-
25
-
-
0034660437
-
Plasminogenactivator inhibitor type 1 and coronary artery disease
-
Kohler, H.P., and Grant, P.J. 2000. Plasminogenactivator inhibitor type 1 and coronary artery disease. N. Engl. J. Med. 342:1792-1801.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1792-1801
-
-
Kohler, H.P.1
Grant, P.J.2
-
26
-
-
0023089665
-
Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
-
Moore, K.L., Andreoli, S.P., Esmon, N.L., Esmon, C.T., and Bang, N.U. 1987. Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J. Clin. Invest. 79:124-130.
-
(1987)
J. Clin. Invest.
, vol.79
, pp. 124-130
-
-
Moore, K.L.1
Andreoli, S.P.2
Esmon, N.L.3
Esmon, C.T.4
Bang, N.U.5
-
27
-
-
0032820571
-
Local variation in expression of pro- and antithrombotic factors in vascular endothelium of human autopsy brain
-
Tohgi, H., Utsugisawa, K., Yoshimura, M., Nagane, Y., and Ukitsu, M. 1999. Local variation in expression of pro- and antithrombotic factors in vascular endothelium of human autopsy brain. Acta Neuropathol. (Berl.). 98:111-118.
-
(1999)
Acta Neuropathol. (Berl.)
, vol.98
, pp. 111-118
-
-
Tohgi, H.1
Utsugisawa, K.2
Yoshimura, M.3
Nagane, Y.4
Ukitsu, M.5
-
28
-
-
0033552883
-
Atherosclerosis - An inflammatory disease
-
Ross, R. 1999. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340:115-126.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
29
-
-
23844540300
-
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice
-
Ragolia, L., et al. 2005. Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice. J. Biol. Chem. 280:29946-29955.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29946-29955
-
-
Ragolia, L.1
-
30
-
-
1642485638
-
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression
-
Kirkiles-Smith, N.C., et al. 2004. IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression. J. Immunol. 172:1391-1396.
-
(2004)
J. Immunol.
, vol.172
, pp. 1391-1396
-
-
Kirkiles-Smith, N.C.1
-
31
-
-
0033932259
-
Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice
-
Zaidi, S.H., et al. 2000. Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice. J. Clin. Invest. 105:1687-1695.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1687-1695
-
-
Zaidi, S.H.1
-
32
-
-
0031443009
-
Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase
-
Hermann, C., Zeiher, A.M., and Dimmeler, S. 1997. Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase. Arterioscler. Thromb. Vasc. Biol. 17:3588-3592.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 3588-3592
-
-
Hermann, C.1
Zeiher, A.M.2
Dimmeler, S.3
-
33
-
-
0035836653
-
Biomechanical activation of vascular endothelium as a determinant of its functional phenotype
-
Garcia-Cardena, G., Comander, J., Anderson, K.R., Blackman, B.R., and Gimbrone, M.A., Jr. 2001. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc. Natl. Acad. Sci. U. S. A. 98:4478-4485.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4478-4485
-
-
Garcia-Cardena, G.1
Comander, J.2
Anderson, K.R.3
Blackman, B.R.4
Gimbrone Jr., M.A.5
-
34
-
-
0035979179
-
DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells
-
McCormick, S.M., et al. 2001. DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells. Proc. Natl. Acad. Sci. U. S. A. 98:8955-8960.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 8955-8960
-
-
McCormick, S.M.1
-
35
-
-
0032102528
-
Effects of hemodynamic forces on gene expression and signal transduction in endothelial cells
-
Chien, S., and Shyy, J.Y. 1998. Effects of hemodynamic forces on gene expression and signal transduction in endothelial cells. Biol. Bull. 194:390-391; discussion 392-393.
-
(1998)
Biol. Bull.
, vol.194
, pp. 390-391
-
-
Chien, S.1
Shyy, J.Y.2
-
36
-
-
0037180745
-
Gene expression profile of human endothelial cells exposed to sustained fluid shear stress
-
Wasserman, S.M., et al. 2002. Gene expression profile of human endothelial cells exposed to sustained fluid shear stress. Physiol. Genomics. 12:13-23.
-
(2002)
Physiol. Genomics
, vol.12
, pp. 13-23
-
-
Wasserman, S.M.1
-
37
-
-
0036372929
-
Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow
-
Brooks, A.R., Lelkes, P.I., and Rubanyi, G.M. 2002. Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiol. Genomics. 9:27-41.
-
(2002)
Physiol. Genomics
, vol.9
, pp. 27-41
-
-
Brooks, A.R.1
Lelkes, P.I.2
Rubanyi, G.M.3
-
38
-
-
21744447354
-
Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases
-
Kumar, A., Lin, Z., SenBanerjee, S., and Jain, M.K. 2005. Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases. Mol. Cell. Biol. 25:5893-5903.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5893-5903
-
-
Kumar, A.1
Lin, Z.2
SenBanerjee, S.3
Jain, M.K.4
-
39
-
-
0030697515
-
The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis
-
Kuo, C.T., et al. 1997. The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes Dev. 11:2996-3006.
-
(1997)
Genes Dev.
, vol.11
, pp. 2996-3006
-
-
Kuo, C.T.1
-
40
-
-
0033566045
-
The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF
-
Bi, W., Drake, C.J., and Schwarz, J.J. 1999. The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev. Biol. 211:255-267.
-
(1999)
Dev. Biol.
, vol.211
, pp. 255-267
-
-
Bi, W.1
Drake, C.J.2
Schwarz, J.J.3
-
41
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos, G.D., et al. 2000. Vascular-specific growth factors and blood vessel formation. Nature. 407:242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
-
42
-
-
0037046220
-
Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide
-
Ohno, N., et al. 2002. Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide. Circulation. 105:1623-1626.
-
(2002)
Circulation
, vol.105
, pp. 1623-1626
-
-
Ohno, N.1
-
43
-
-
0345688078
-
Thrombomodulin and tissue factor pathway inhibitor in endocardium of rapidly paced rat atria
-
Yamashita, T., et al. 2003. Thrombomodulin and tissue factor pathway inhibitor in endocardium of rapidly paced rat atria. Circulation. 108:2450-2452.
-
(2003)
Circulation
, vol.108
, pp. 2450-2452
-
-
Yamashita, T.1
-
44
-
-
22844434684
-
Statins exert endothelial atheroprotective effects via the KLF2 transcription factor
-
Parmar, K.M., et al. 2005. Statins exert endothelial atheroprotective effects via the KLF2 transcription factor. J. Biol. Chem. 280:26714-26719.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26714-26719
-
-
Parmar, K.M.1
-
45
-
-
23244457776
-
Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells
-
Sen-Banerjee, S., et al. 2005. Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells. Circulation. 112:720-726.
-
(2005)
Circulation
, vol.112
, pp. 720-726
-
-
Sen-Banerjee, S.1
-
46
-
-
0036675545
-
A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress wave forms
-
Blackman, B.R., Garcia-Cardena, G., and Gimbrone, M.A., Jr. 2002. A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress wave forms. J. Biomech. Eng. 124:397-407.
-
(2002)
J. Biomech. Eng.
, vol.124
, pp. 397-407
-
-
Blackman, B.R.1
Garcia-Cardena, G.2
Gimbrone Jr., M.A.3
-
47
-
-
0344464733
-
Gene Expression Dynamics Inspector (GEDI): For integrative analysis of expression profiles
-
Eichler, G.S., Huang, S., and Ingber, D.E. 2003. Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics. 19:2321-2322.
-
(2003)
Bioinformatics
, vol.19
, pp. 2321-2322
-
-
Eichler, G.S.1
Huang, S.2
Ingber, D.E.3
-
48
-
-
0029022062
-
The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide
-
Sessa, W.C., et al. 1995. The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. J. Biol. Chem. 270:17641-17644.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17641-17644
-
-
Sessa, W.C.1
|