Hemodynamic shear stresses in mouse aortas: Implications for atherogenesis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 27, Issue 2, 2007, Pages 346-351

  Suo, Jin ^a   Ferrara, Dardo E ^c   Sorescu, Dan ^c   Guldberg, Robert E ^b   Taylor, W Robert ^a,c,d   Giddens, Don P ^a,e  

^a Emory University   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ATLANTA VA MEDICAL CENTER   (United States)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Adhesion molecules; Atherosclerosis; Computational fluid dynamics; Micro CT; Two photon microscopy; Wall shear stress

Indexed keywords

GENE PRODUCT; INTERCELLULAR ADHESION MOLECULE 1; QUANTUM DOT; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL TISSUE; AORTA; AORTA INTIMA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; DISEASE ASSOCIATION; FLUID FLOW; GENE EXPRESSION; HEMODYNAMIC STRESS; HUMAN VERSUS ANIMAL COMPARISON; INFLAMMATION; MATHEMATICAL MODEL; METHODOLOGY; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SPECIES DIFFERENCE; ULTRASOUND;

ANIMALS; AORTA, THORACIC; ATHEROSCLEROSIS; COMPUTER SIMULATION; GENE EXPRESSION REGULATION; INTERCELLULAR ADHESION MOLECULE-1; MATHEMATICS; MICE; MICE, INBRED C57BL; REGIONAL BLOOD FLOW; RISK FACTORS; STRESS, MECHANICAL; TUNICA INTIMA; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR RESISTANCE;

EID: 33846413954     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000253492.45717.46     Document Type: Article

References (28)

1. Caro CG, Fitz-Gerald JM, Schroter RC. Atheroma and arterial wall shear. Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proc R Soc Lond B Biol Sci. 1971;177:109-159.
2. Zarins CK, Giddens DP, Bharadvaj BK, Sottiurai VS, Mabon RF, Glagov S. Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res. 1983;53:502-514.
3. Ku DN, Giddens DP, Zarins CK, Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis. 1985;5:293-302.
4. Reardon CA, Getz GS. Mouse models of atherosclerosis. Curr Opin Lipidol. 2001;12:167-173.
5. Choudhury RP, Aguinaldo JG, Rong JX, Kulak JL, Kulak AR, Reis ED, Fallon JT, Fuster V, Fisher EA, Fayad ZA. Atherosclerotic lesions in genetically modified mice quantified in vivo by non-invasive high-resolution magnetic resonance microscopy. Atherosclerosis. 2002;162:315-321.
6. Duvall CL, Taylor WR, Weiss D, Guldberg RE. Quantitative microcomputed tomography analysis of collateral vessel development after ischemic injury. Am J Physiol Heart Circ Physiol. 2004;287:H302-H310.
7. Suo J, Oshinski J, Giddens DP. Effects of wall motion and compliance on flow patterns in the ascending aorta. J Biomech Eng. 2003;125:347-354.
8. Ferrara DE, Weiss D, Carnell PH, Vito RP, Vega D, Gao X, Nie S, Taylor WR. Quantitative 3D fluorescence technique for the analysis of en face preparations of arterial walls using quantum dot nanocrystals and two-photon excitation laser scanning microscopy. Am J Physiol Regul Integr Comp Physiol. 2006;290:R114-R123.
9. Langille BL. Remodeling of developing and mature arteries: endothelium, smooth muscle and matrix. J Cardiovasc Pharmacol 21 Suppl. 1993;1:S11-S17.
10. Greve JM, Les AS, Tang BT, Draney Blomme MT, Wilson NM, Dalman RL, Pelc NJ, Taylor CA. Allometric Scaling of Wall Shear Stress from Mouse to Man: Quantification Using Cine Phase-Contrast MRI and Computational Fluid Dynamics. Am J Physiol Heart Circ Physiol. In press.
11. Fry DL. Acute vascular endothelial changes associated with increased blood velocity gradients. Circ Res. 1968;22:165-197.
12. Gibson CM, Diaz L, Kandarpa K, Sacks FM, Pasternak RC, Sandor T, Feldman C, Stone PH. Relation of vessel wall shear stress to atherosclerosis progression in human coronary arteries. Arterioscler Thromb. 1993;13:310-315.
13. Gnasso A, Irace C, Carallo C, De Franceschi MS, Motti C, Mattioli PL, Pujia A. In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis. Stroke. 1997;28:993-998.
14. Moore JE, Jr., Xu C, Glagov S, Zarins CK, Ku DN. Fluid wall shear stress measurements in a model of the human abdominal aorta: oscillatory behavior and relationship to atherosclerosis. Atherosclerosis. 1994;110:225-240.
15. Iiyama K, Hajra L, Iiyama M, Li H, DiChiara M, Medoff BD, Cybulsky MI. Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res. 1999;85:199-207.
16. Nakashima Y, Raines EW, Plump AS, Breslow JL, Ross R. Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arterioscler Thromb Vasc Biol. 1998;18:842-851.
17. Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassegue B, Griendling KK, Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res. 2004;95:773-779.
18. Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S, Giddens DP, Griendling KK, Harrison DG, Jo H. Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. J Biol Chem. 2003;278:47291- 47298.
19. Davies PF, Dewey CF, Jr., Bussolari SR, Gordon EJ, Gimbrone MA, Jr. Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest. 1984;73:1121-1129.
20. Williams DA. Intact capillaries sensitive to rate, magnitude, and pattern of shear stress stimuli as assessed by hydraulic conductivity (Lp). Microvasc Res. 2003;66:147-158.
21. Ando J, Ohtsuka A, Korenaga R, Kawamura T, Kamiya A. Wall shear stress rather than shear rate regulates cytoplasmic Ca++ responses to flow in vascular endothelial cells. Biochem Biophys Res Commun. 1993;190:716-723.
22. Chappell DC, Varner SE, Nerem RM, Medford RM, Alexander RW. Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium. Circ Res. 1998;82:532-539.
23. De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res. 1998;82:1094-1101.
24. Davies PF. Flow-mediated endothelial mechanotransduction. Physiol Rev. 1995;75:519-560.
25. Endres M, Laufs U, Merz H, Kaps M. Focal expression of intercellular adhesion molecule-1 in the human carotid bifurcation. Stroke. 1997;28:77-82.
26. Weinberg PD and Ethier CR. Twenty-fold difference in hemodynamic wall shear stress between murine and human aortas. J Biomech. In press.
27. McGillicuddy CJ, Carrier MJ, Weinberg PD. Distribution of lipid deposits around aortic branches of mice lacking LDL receptors and apolipoprotein E. Arterioscler Thromb Vasc Biol. 2001;21:1220-1225.
28. Zeng D, Ding Z, Friedman MH, Ethier CR. Effects of cardiac motion on right coronary artery hemodynamics. Ann Biomed Eng. 2003;31:420-429.