메뉴 건너뛰기




Volumn 113, Issue 3, 2004, Pages 370-378

Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LAMIN A; LAMIN C; TRANSCRIPTION FACTOR;

EID: 1542317663     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200419670     Document Type: Article
Times cited : (871)

References (39)
  • 1
    • 0033749567 scopus 로고    scopus 로고
    • Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes
    • Liu, J., et al. 2000. Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes. Mol. Biol. Cell. 11:3937-3947.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 3937-3947
    • Liu, J.1
  • 2
    • 0036843975 scopus 로고    scopus 로고
    • Lamins: Building blocks or regulators of gene expression?
    • Hutchison, C.J. 2002. Lamins: building blocks or regulators of gene expression? Nat. Rev. Mol. Cell Biol. 3:848-858.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 848-858
    • Hutchison, C.J.1
  • 3
    • 0043172367 scopus 로고    scopus 로고
    • Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo
    • Holt, I., et al. 2003. Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo. J. Cell Sci. 116:3027-3035.
    • (2003) J. Cell Sci. , vol.116 , pp. 3027-3035
    • Holt, I.1
  • 4
    • 0033615969 scopus 로고    scopus 로고
    • Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy
    • Sullivan, T., et al. 1999. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J. Cell Biol. 147:913-920.
    • (1999) J. Cell Biol. , vol.147 , pp. 913-920
    • Sullivan, T.1
  • 5
    • 0026687406 scopus 로고
    • The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase
    • Biamonti, G., et al. 1992. The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase. Mol. Cell. Biol. 12:3499-3506.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3499-3506
    • Biamonti, G.1
  • 6
    • 0027257461 scopus 로고
    • Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C
    • Lin, F., and Worman, H.J. 1993. Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C. J. Biol. Chem. 268:16321-16326.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16321-16326
    • Lin, F.1    Worman, H.J.2
  • 7
    • 0028342511 scopus 로고
    • Identification and cloning of an mRNA coding for a germ cell-specific A-type lamin in mice
    • Furukawa, K., Inagaki, H., and Hotta, Y. 1994. Identification and cloning of an mRNA coding for a germ cell-specific A-type lamin in mice. Exp. Cell Res. 212:426-430.
    • (1994) Exp. Cell Res. , vol.212 , pp. 426-430
    • Furukawa, K.1    Inagaki, H.2    Hotta, Y.3
  • 8
    • 0028980880 scopus 로고
    • Structural organization of the human gene (LMNB1) encoding nuclear lamin B1
    • Lin, F., and Worman, H.J. 1995. Structural organization of the human gene (LMNB1) encoding nuclear lamin B1. Genomics. 27:230-236.
    • (1995) Genomics , vol.27 , pp. 230-236
    • Lin, F.1    Worman, H.J.2
  • 9
    • 0029932434 scopus 로고    scopus 로고
    • An alternative splicing product of the lamin A/C gene lacks exon 10
    • Machiels, B.M., et al. 1996. An alternative splicing product of the lamin A/C gene lacks exon 10. J. Biol. Chem. 271:9249-9253.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9249-9253
    • Machiels, B.M.1
  • 10
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth, J., Elbashir, S.M., Bechert, K., Tuschl, T., and Weber, K. 2001. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114:4557-4565.
    • (2001) J. Cell Sci. , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuschl, T.4    Weber, K.5
  • 11
    • 0032977685 scopus 로고    scopus 로고
    • Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy
    • Bonne, G., et al. 1999. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nat. Genet. 21:285-288.
    • (1999) Nat. Genet. , vol.21 , pp. 285-288
    • Bonne, G.1
  • 12
    • 0033518282 scopus 로고    scopus 로고
    • Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease
    • Fatkin, D., et al. 1999. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N. Engl. J. Med. 341:1715-1724.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1715-1724
    • Fatkin, D.1
  • 13
    • 0034059075 scopus 로고    scopus 로고
    • Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy
    • Cao, H., and Hegele, R.A. 2000. Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy. Hum. Mol. Genet. 9:109-112.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 109-112
    • Cao, H.1    Hegele, R.A.2
  • 14
    • 0033951216 scopus 로고    scopus 로고
    • LMNA, encoding lamin A/C, is mutated in partial lipodystrophy
    • Shackleton, S., et al. 2000. LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. Nat. Genet. 24:153-156.
    • (2000) Nat. Genet. , vol.24 , pp. 153-156
    • Shackleton, S.1
  • 15
    • 0036347096 scopus 로고    scopus 로고
    • Life at the edge: The nuclear envelope and human disease
    • Burke, B., and Stewart, C.L. 2002. Life at the edge: the nuclear envelope and human disease. Nat. Rev. Mol. Cell Biol. 3:575-585.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 575-585
    • Burke, B.1    Stewart, C.L.2
  • 16
    • 10744229294 scopus 로고    scopus 로고
    • Lamin A truncation in Hutchinson-Gilford progeria
    • De Sandre-Giovannoli, A., et al. 2003. Lamin A truncation in Hutchinson-Gilford progeria. Science. 300:2055.
    • (2003) Science , vol.300 , pp. 2055
    • De Sandre-Giovannoli, A.1
  • 17
    • 0037673950 scopus 로고    scopus 로고
    • Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
    • Eriksson, M., et al. 2003. Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature. 423:293-298.
    • (2003) Nature , vol.423 , pp. 293-298
    • Eriksson, M.1
  • 18
    • 0035696932 scopus 로고    scopus 로고
    • Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy
    • Raharjo, W.H., Enarson, P., Sullivan, T., Stewart, C.L., and Burke, B. 2001. Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy. J. Cell Sci. 114:4447-4457.
    • (2001) J. Cell Sci. , vol.114 , pp. 4447-4457
    • Raharjo, W.H.1    Enarson, P.2    Sullivan, T.3    Stewart, C.L.4    Burke, B.5
  • 19
    • 0035691915 scopus 로고    scopus 로고
    • Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene
    • Vigouroux, C., et al. 2001. Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene. J. Cell Sci. 114:4459-4468.
    • (2001) J. Cell Sci. , vol.114 , pp. 4459-4468
    • Vigouroux, C.1
  • 20
    • 0031660703 scopus 로고    scopus 로고
    • Local measurements of viscoelastic parameters of adherent cell surfaces by magnetic bead microrheometry
    • Bausch, A.R., Ziemann, F., Boulbitch, A.A., Jacobson, K., and Sackmann, E. 1998. Local measurements of viscoelastic parameters of adherent cell surfaces by magnetic bead microrheometry. Biophys. J. 75:2038-2049.
    • (1998) Biophys. J. , vol.75 , pp. 2038-2049
    • Bausch, A.R.1    Ziemann, F.2    Boulbitch, A.A.3    Jacobson, K.4    Sackmann, E.5
  • 22
    • 0031014645 scopus 로고    scopus 로고
    • Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells
    • Cheng, G.C., et al. 1997. Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells. Circ. Res. 80:28-36.
    • (1997) Circ. Res. , vol.80 , pp. 28-36
    • Cheng, G.C.1
  • 23
    • 0037023649 scopus 로고    scopus 로고
    • Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy
    • De Keulenaer, G.W., et al. 2002. Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy. Circ. Res. 90:690-696.
    • (2002) Circ. Res. , vol.90 , pp. 690-696
    • De Keulenaer, G.W.1
  • 24
    • 0036644594 scopus 로고    scopus 로고
    • Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis
    • Remoli, M.E., et al. 2002. Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis. J. Immunol. 169:366-374.
    • (2002) J. Immunol. , vol.169 , pp. 366-374
    • Remoli, M.E.1
  • 25
    • 0032066928 scopus 로고    scopus 로고
    • Assessment of strain field in endothelial cells subjected to uniaxial deformation of their substrate
    • Caille, N., Tardy, Y., and Meister, J.J. 1998. Assessment of strain field in endothelial cells subjected to uniaxial deformation of their substrate. Ann. Biomed. Eng. 26:409-416.
    • (1998) Ann. Biomed. Eng. , vol.26 , pp. 409-416
    • Caille, N.1    Tardy, Y.2    Meister, J.J.3
  • 26
    • 0036514780 scopus 로고    scopus 로고
    • Uni-axial cyclic stretch induces the activation of transcription factor nuclear factor kappaB in human fibroblast cells
    • Inoh, H., et al. 2002. Uni-axial cyclic stretch induces the activation of transcription factor nuclear factor kappaB in human fibroblast cells. FASEB J. 16:405-407.
    • (2002) FASEB J. , vol.16 , pp. 405-407
    • Inoh, H.1
  • 27
    • 0034814966 scopus 로고    scopus 로고
    • MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts
    • Granet, C., Boutahar, N., Vico, L., Alexandre, C., and Lafage-Proust, M.H. 2001. MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts. Biochem. Biophys. Res. Commun. 284:622-631.
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 622-631
    • Granet, C.1    Boutahar, N.2    Vico, L.3    Alexandre, C.4    Lafage-Proust, M.H.5
  • 28
    • 0036137722 scopus 로고    scopus 로고
    • Contribution of the nucleus to the mechanical properties of endothelial cells
    • Caille, N., Thoumine, O., Tardy, Y., and Meister, J.J. 2002. Contribution of the nucleus to the mechanical properties of endothelial cells. J. Biomech. 35:177-187.
    • (2002) J. Biomech. , vol.35 , pp. 177-187
    • Caille, N.1    Thoumine, O.2    Tardy, Y.3    Meister, J.J.4
  • 29
    • 0036966367 scopus 로고    scopus 로고
    • Increased solubility of lamins and redistribution of lamin C in X-linked Emery-Dreifuss muscular dystrophy fibroblasts
    • Markiewicz, E., et al. 2002. Increased solubility of lamins and redistribution of lamin C in X-linked Emery-Dreifuss muscular dystrophy fibroblasts. J. Struct. Biol. 140:241-253.
    • (2002) J. Struct. Biol. , vol.140 , pp. 241-253
    • Markiewicz, E.1
  • 30
    • 0030272704 scopus 로고    scopus 로고
    • Intermediate filament-mediated stretch-induced changes in chromatin: A hypothesis for growth initiation in cardiac myocytes
    • Bloom, S., Lockard, V.G., and Bloom, M. 1996. Intermediate filament-mediated stretch-induced changes in chromatin: a hypothesis for growth initiation in cardiac myocytes. J. Mol. Cell. Cardiol. 28:2123-2127.
    • (1996) J. Mol. Cell. Cardiol. , vol.28 , pp. 2123-2127
    • Bloom, S.1    Lockard, V.G.2    Bloom, M.3
  • 31
    • 0031017220 scopus 로고    scopus 로고
    • Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    • Maniotis, A.J., Chen, C.S., and Ingber, D.E. 1997. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc. Natl. Acad. Sci. U. S. A. 94:849-854.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 849-854
    • Maniotis, A.J.1    Chen, C.S.2    Ingber, D.E.3
  • 32
    • 0034638842 scopus 로고    scopus 로고
    • Nuclear lamins A and B1: Different pathways of assembly during nuclear envelope formation in living cells
    • Moir, R.D., Yoon, M., Khuon, S., and Goldman, R.D. 2000. Nuclear lamins A and B1: different pathways of assembly during nuclear envelope formation in living cells. J. Cell Biol. 151:1155-1168.
    • (2000) J. Cell Biol. , vol.151 , pp. 1155-1168
    • Moir, R.D.1    Yoon, M.2    Khuon, S.3    Goldman, R.D.4
  • 33
    • 0036848357 scopus 로고    scopus 로고
    • In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C
    • Dreuillet, C., Tillit, J., Kress, M., and Ernoult-Lange, M. 2002. In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C. Nucleic Acids Res. 30:4634-4642.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4634-4642
    • Dreuillet, C.1    Tillit, J.2    Kress, M.3    Ernoult-Lange, M.4
  • 34
    • 0036537888 scopus 로고    scopus 로고
    • A novel interaction between lamin A and SREBP1: Implications for partial lipodystrophy and other laminopathies
    • Lloyd, D.J., Trembath, R.C., and Shackleton, S. 2002. A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies. Hum. Mol. Genet. 11:769-777.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 769-777
    • Lloyd, D.J.1    Trembath, R.C.2    Shackleton, S.3
  • 35
    • 0037049554 scopus 로고    scopus 로고
    • Lamin A/C speckles mediate spatial organization of splicing factor compartments and RNA polymerase II transcription
    • Kumaran, R.I., Muralikrishna, B., and Parnaik, V.K. 2002. Lamin A/C speckles mediate spatial organization of splicing factor compartments and RNA polymerase II transcription. J. Cell Biol. 159:783-793.
    • (2002) J. Cell Biol. , vol.159 , pp. 783-793
    • Kumaran, R.I.1    Muralikrishna, B.2    Parnaik, V.K.3
  • 36
    • 0037128211 scopus 로고    scopus 로고
    • Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription
    • Spann, T.P., Goldman, A.E., Wang, C., Huang, S., and Goldman, R.D. 2002. Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription. J. Cell Biol. 156:603-608.
    • (2002) J. Cell Biol. , vol.156 , pp. 603-608
    • Spann, T.P.1    Goldman, A.E.2    Wang, C.3    Huang, S.4    Goldman, R.D.5
  • 37
    • 0030465544 scopus 로고    scopus 로고
    • Lamin proteolysis facilitates nuclear events during apoptosis
    • Rao, L., Perez, D., and White, E. 1996. Lamin proteolysis facilitates nuclear events during apoptosis. J. Cell Biol. 135:1441-1455.
    • (1996) J. Cell Biol. , vol.135 , pp. 1441-1455
    • Rao, L.1    Perez, D.2    White, E.3
  • 38
    • 0037336186 scopus 로고    scopus 로고
    • Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: A possible role in Duchenne muscular dystrophy
    • Kumar, A., and Boriek, A.M. 2003. Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEB J. 17:386-396.
    • (2003) FASEB J. , vol.17 , pp. 386-396
    • Kumar, A.1    Boriek, A.M.2
  • 39
    • 0035697055 scopus 로고    scopus 로고
    • Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy
    • Östlund, C., Bonne, G., Schwartz, K., and Worman, H.J. 2001. Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy. J. Cell Sci. 114:4435-4445.
    • (2001) J. Cell Sci. , vol.114 , pp. 4435-4445
    • Östlund, C.1    Bonne, G.2    Schwartz, K.3    Worman, H.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.