Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 3, 2007, Pages

  Platt, Manu O ^a   Ankeny, Randall F ^a   Shi, Guo Ping ^c   Weiss, Daiana ^b   Vega, J David ^b   Taylor, W Robert ^b   Jo, Hanjoong ^a,b,d  

^a Emory University   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cathepsin K; Endothelial cells; Extracellular matrix protease; Shear stress; Vascular remodeling and atherosclerosis

Indexed keywords

CATHEPSIN K; ELASTASE; GELATINASE; PROTEINASE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; ENDOTHELIUM CELL; GENE CONTROL; GENE SILENCING; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; ATHEROSCLEROSIS; CATHEPSINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HUMANS; MICE; MICE, INBRED C57BL; RNA, MESSENGER; STRESS, MECHANICAL;

EID: 33847747817     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00954.2006     Document Type: Article

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