Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10417-10422

  Topper, James N ^a   Cai, Jiexing ^b   Falb, Dean ^b   Gimbrone Jr , Michael A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Atherosclerosis; Differential display; Hemodynamic forces; Vascular endothelium

Indexed keywords

GENE PRODUCT; MANGANESE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; SUPEROXIDE DISMUTASE;

ARTERY WALL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HEMODYNAMICS; HUMAN; HUMAN CELL; LAMINAR FLOW; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; TURBULENT FLOW; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DNA PRIMERS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; NITRIC OXIDE SYNTHASE; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STRESS, MECHANICAL; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC; UMBILICAL VEINS;

EID: 0029790770     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10417     Document Type: Article

References (53)

1. Ross, R. (1993) Nature (London) 362, 801-809.
2. Gimbrone, M. A., Jr. (1995) in Molecular Cardiovascular Medicine, ed. Haber, E. (Sci. Am. Med., New York), pp. 49-61.
3. Gimbrone, M. A., Jr., Cybulsky, M. I., Kume, N., Collins, T. & Resnick, N. (1995) Ann. N.Y. Acad. Sci. 748, 122-132.
4. Fry, D. L. (1973) CIBA Found. Symp. 12, 96-118.
5. Caro, C. G., Fitzgerald, J. M. & Schroter, R. C. (1969) Nature (London) 223, 1159-1161.
6. Cornhill, J. F. & Roach, M. R. (1976) Atherosclerosis 23, 489-499.
7. Karino, Y. & Motomiya, M. (1983) Biorheology 20, 119-127.
8. Zarins, C. K., Giddens, D. P., Bharadvaj, B. K., Sottiurai, V. S., Mabon, R. F. & Glagov, S. (1983) Circ. Res. 53, 502-514.
9. Ku, D. N., Giddens, D. P., Zarins, C. K. & Glagov, S. (1985) Arteriosclerosis 5, 293-301.
10. Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L. & Ross, R. (1994) Arterioscler. Thromb. 14, 133-140.
11. Davies, P. F. (1995) Physiol. Rev. 75, 519-560.
12. Resnick, N. & Gimbrone, M. A., Jr. (1995) FASEB J. 9, 874-882.
13. Bussolari, S. R., Dewey, C. F., Jr., & Gimbrone, M. A., Jr. (1982) Rev. Sci. Instrum. 53, 1851-1854.
14. Sdougos, H. P., Bussolari, S. R. & Dewey, C. F. (1984) J. Fluid Mech. 138, 379-404.
15. Liang, P. & Pardee, A. B. (1992) Science 257, 967-971.
16. Bevilacqua, M., Stengelin, S., Gimbrone, M. A., Jr., & Seed, B. (1989) Science 243, 1160-1165.
17. Cheifetz, S., Bellon, T., Cales, C., Vera, S., Bernabeus, C., Massague, J. & Letarte, M. (1992) J. Biol. Chem. 267, 19027-19030.
18. Davies, P. F., Remuzzi, A., Gordon, E. J., Dewey, C. F., Jr., & Gimbrone, M. A., Jr. (1986) Proc. Natl. Acad. Sci. USA 83, 2114-2117.
19. Pober, J. S. & Cotran, R. S. (1990) Physiol. Rev. 70, 427-451.
20. Pritchard, K. A., O'Bannion, M. K., Miano, J. M., Vlasic N., Bhatia, U. G., Young, D. A. & Stemerman, M. B. (1994) J. Biol. Chem. 269, 8504-8509.
21. Jones, D. A., Carlton, D. P., McIntyre, T. M., Simmerman, G. A. & Prescott, S. M. (1993) J. Biol. Chem. 266, 9049-9054.
22. Ristimaki, A., Garfinkel, S., Wessendorf, J., Maciag, T. & Hla, T. (1994) J. Biol. Chem. 269, 11769-11775.
23. Suzuki, K., Tatsumi, H., Satoh, S., Senda, T., Nakata, T., Fujii, J. & Taniguchi, N. (1993) Am. J. Physiol 265, H1173-H1178.
24. Nagel, T., Resnick, N., Atkinson, W. J., Dewey, C. F. Jr., & Gimbrone, M. A., Jr. (1994) J. Clin. Invest. 94, 885-891.
25. Hsieh, H. J., Li, N. Q. & Frangos, J. (1991) Am. J. Physiol. 260, H642-H646.
26. Hsieh, H., Li, N. & Frangos, J. A. (1992) J. Cell. Physiol. 150, 552-558.
27. Resnick, N., Collins, T., Atkinson, W., Bonthron, D. T., Dewey, C. F., Jr., & Gimbrone, M. A., Jr., (1993) Proc. Natl. Acad. Sci. USA 90, 4591-4595.
28. Khachigian, L. M., Resnick, N., Gimbrone, M. A., Jr., & Collins, T. (1995) J. Clin. Invest. 96, 1169-1175.
29. Shyy, J. Y., Lin, M. C., Han, J., Lu, Y., Petrime, M. & Chien, S. (1995) Proc. Natl. Acad. Sci. USA 92, 8069-8073.
30. Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C. & Witzum, J. L. (1989) N. Engl. J. Med. 320, 915-924.
31. Alexander, R. W. (1995) Hypertension 25, 155-161.
32. Kume, N., Cybulsky, M. I. & Gimbrone, M. A., Jr. (1992) J. Clin. Invest. 90, 1138-1144.
33. Kume, N. & Gimbrone, M. A., Jr. (1994) J. Clin. Invest. 93, 907-911.
34. Offermann, M. K. & Medford, R. M. (1994) Heart Dis. Stroke 3, 52-57.
35. Marui, N., Offermann, M. K., Swerlick, R., Kunsch, C., Rosen, C. A., Ahmad, M., Alexander, R. W. & Medford, R. M. (1993) J. Clin. Invest. 92, 1866-1874.
36. Cybulsky, M. I. & Gimbrone, M. A., Jr. (1991) Science 251, 788-791.
37. Li, H., Cybulsky, M. I., Gimbrone, M. A., Jr., & Libby, P. (1993) Arterioscler. Thromb. 13, 197-204.
38. Collins, T. (1993) Lab Invest. 68, 499-508.
39. Wispe, J. R., Warner, B. B., Clark, J. C., Dey, C. R., Nwuman, J., Glasser, S. W., Crapo, J. D., Chang, L.-Y. & Whitsett, J. A. (1992) J. Biol. Chem. 267, 23937-23941.
40. Lindau-Shepard, B., Shaffer, J. B. & Vecchio, P. J. D. (1994) J. Cell. Physiol. 161, 237-242.
41. Pomerantz, K. B. & Hajar, D. P. (1989) Arteriosclerosis 9, 413-429.
42. Vane, J. R. & Botting, R. M. (1995) Am. J. Cardiol. 75, 3A-10A.
43. Hla, T. & Neilson, K. (1992) Proc. Natl. Acad. Sci. USA 89, 7384-7388.
44. Vane, J. R., Mitchell, J. A., Appleton, I., Tomlinson, A., Bishop-Bailey, D., Croxtall, J. & Willoughby, D. A. (1994) Proc. Natl. Acad. Sci. USA 91, 2046-2050.
45. Tsujii, M. & Dubois, R. N. (1995) Cell 83, 493-501.
46. Morham, S. G., Langenbach, J. R., Loftin, C. D., Tiano, H. F., Vouloumaos, N., Jennette, J. C., Mahler, J. F., Kluckman, K. D., Ledford, A., Lee, C. A. & Smithies, O. (1995) Cell 83, 473-482.
47. Zembowicz, A., Jones, S. L. & Wu, K. K. (1995) J. Clin. Invest. 96, 1688-1692.
48. Dusting, G. (1995) J. Vasc. Res. 32, 143-161.
49. Wennmalm, A. (1994) J. Intern. Med. 235, 317-327.
50. DeCaterina, R., Libby, P., Thannickal, V. J., Peng, H.-B., Rajavashisth, T. B., Gimbrone, M. A., Jr., Shin, W. S. & Liao, J. K. (1995) J. Clin. Invest. 96, 60-68.
51. Nishida, K., Harrison, D. G., Nawas, J. P., Fisher, A. A., Dockery, S. P., Uematsu, M., Nerem, R. M., Alexander, R. W. & Murphy, T. J. (1992) J. Clin. Invest. 90, 2092-2096.
52. Ando, J., Tsuboi, H., Korenaga, R., Takada, Y., Toyama-Sorimachi, N., Miyasaka, M. & Kamiya, A. (1994) Am. J. Physiol. 267, C679-C687.
53. Inoe, N., Ramasamy, S., Fukai, T., Nerem, R. M. & Harrison, D. G. (1996) Circ. Res. 79, 32-37.