Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis

Journal of Clinical Investigation

Volumn 124, Issue 7, 2014, Pages 3187-3199

  Dunn, Jessilyn ^a   Qiu, Haiwei ^a   Kim, Soyeon ^a   Jjingo, Daudi ^b   Hoffman, Ryan ^a   Kim, Chan Woo ^a   Jang, Inhwan ^a   Son, Dong Ju ^a   Kim, Daniel ^a   Pan, Chenyi ^b   Fan, Yuhong ^b   Jordan, I King ^b   Jo, Hanjoong ^a,c  

^a Emory University   (United States)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 3; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; EXPERIMENTAL ATHEROSCLEROSIS; GENE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; MOUSE; MOUSE MODEL; NONHUMAN; OSCILLATORY SHEAR STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; TRANSCRIPTION INITIATION SITE; WESTERN BLOTTING;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; AZACITIDINE; DISEASE MODELS, ANIMAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; ENDOTHELIAL CELLS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOPROTEINS; PLAQUE, ATHEROSCLEROTIC; PROMOTER REGIONS, GENETIC; REGIONAL BLOOD FLOW; RNA, MESSENGER; STRESS, MECHANICAL;

EID: 84903784400     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI74792     Document Type: Article

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