메뉴 건너뛰기




Volumn 7, Issue 2, 2014, Pages 218-224

Epigenetic mechanism in regulation of endothelial function by disturbed flow: Induction of DNA hypermethylation by DNMT1

Author keywords

DNA methylation; DNMT1; Endothelial cells; Oscillatory shear flow

Indexed keywords

CYTOSINE; DNA METHYLTRANSFERASE 1;

EID: 84903759403     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-014-0325-z     Document Type: Article
Times cited : (77)

References (29)
  • 1
    • 57049160500 scopus 로고    scopus 로고
    • Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: A contribution to the current debate on disease pathogenesis
    • Casaccia-Bonnefil, P., G. Pandozy, and F. Mastronardi. Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis. Prog. Neurobiol. 86:368-378, 2008.
    • (2008) Prog. Neurobiol. , vol.86 , pp. 368-378
    • Casaccia-Bonnefil, P.1    Pandozy, G.2    Mastronardi, F.3
  • 4
    • 78751652828 scopus 로고    scopus 로고
    • Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives
    • Chiu, J. J., and S. Chien. Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol. Rev. 91:327-387, 2011.
    • (2011) Physiol. Rev. , vol.91 , pp. 327-387
    • Chiu, J.J.1    Chien, S.2
  • 7
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P. A., and S. B. Baylin. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3:415-428, 2002. (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 8
    • 84894493712 scopus 로고    scopus 로고
    • Heat shock prevents insulin resistance induced vascular complications by augmenting angiotensin-(1-7) signalling
    • Karpe, P. A., and K. Tikoo. Heat shock prevents insulin resistance induced vascular complications by augmenting angiotensin-(1-7) signalling. Diabetes 63:1124-1139, 2013.
    • (2013) Diabetes , vol.63 , pp. 1124-1139
    • Karpe, P.A.1    Tikoo, K.2
  • 10
    • 0346122781 scopus 로고    scopus 로고
    • Flow-Induced Vascular Remodeling in the Mouse: A Model for Carotid Intima-Media Thickening
    • DOI 10.1161/01.ATV.0000103120.06092.14
    • Korshunov, V. A., and B. C. Berk. Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickening. Arterioscler.Thromb.Vasc. Biol. 23:2185-2191, 2003. (Pubitemid 37532318)
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.12 , pp. 2185-2191
    • Korshunov, V.A.1    Berk, B.C.2
  • 11
    • 84881027287 scopus 로고    scopus 로고
    • Histone and DNA methylation-mediated epigenetic downregulation of endothelial kruppel-like factor 2 by low-density lipoprotein cholesterol
    • Kumar, A., S. Kumar, A. Vikram, T. A. Hoffman, A. Naqvi, C. M. Lewarchik, Y. R. Kim, and K. Irani. Histone and DNA methylation-mediated epigenetic downregulation of endothelial kruppel-like factor 2 by low-density lipoprotein cholesterol. Arterioscler. Thromb. Vasc. Biol. 33:1936-1942, 2013.
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 1936-1942
    • Kumar, A.1    Kumar, S.2    Vikram, A.3    Hoffman, T.A.4    Naqvi, A.5    Lewarchik, C.M.6    Kim, Y.R.7    Irani, K.8
  • 13
    • 84863135417 scopus 로고    scopus 로고
    • Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow
    • Lee, D. Y., C. I. Lee, T. E. Lin, S. H. Lim, J. Zhou, Y. C. Tseng, S. Chien, and J. J. Chiu. Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow. Proc. Natl Acad. Sci. U.S.A. 109:1967-1972, 2012.
    • (2012) Proc. Natl Acad. Sci. U.S.A. , vol.109 , pp. 1967-1972
    • Lee, D.Y.1    Lee, C.I.2    Lin, T.E.3    Lim, S.H.4    Zhou, J.5    Tseng, Y.C.6    Chien, S.7    Chiu, J.J.8
  • 14
    • 84875808286 scopus 로고    scopus 로고
    • Thrombospondin-1 expression in melanoma is blocked by methylation and targeted reversal by 5-aza-deoxycytidine suppresses angiogenesis
    • Lindner, D. J., Y. Wu, R. Haney, B. S. Jacobs, J. P. Fruehauf, R. Tuthill, and E. C. Borden. Thrombospondin-1 expression in melanoma is blocked by methylation and targeted reversal by 5-aza-deoxycytidine suppresses angiogenesis. Matrix Biol. 32:123-132, 2013.
    • (2013) Matrix Biol. , vol.32 , pp. 123-132
    • Lindner, D.J.1    Wu, Y.2    Haney, R.3    Jacobs, B.S.4    Fruehauf, J.P.5    Tuthill, R.6    Borden, E.C.7
  • 15
    • 68949096744 scopus 로고    scopus 로고
    • Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease
    • Mastroeni, D., A. McKee, A. Grover, J. Rogers, and P. D. Coleman. Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS ONE 4:e6617, 2009.
    • (2009) PLoS ONE , vol.4
    • Mastroeni, D.1    McKee, A.2    Grover, A.3    Rogers, J.4    Coleman, P.D.5
  • 17
    • 77955238361 scopus 로고    scopus 로고
    • Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
    • Patel, K., J. Dickson, S. Din, K. Macleod, D. Jodrell, and B. Ramsahoye. Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme. Nucleic Acids Res. 38:4313-4324, 2010.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 4313-4324
    • Patel, K.1    Dickson, J.2    Din, S.3    Macleod, K.4    Jodrell, D.5    Ramsahoye, B.6
  • 18
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela, A., and M. Esteller. Epigenetic modifications and human disease. Nat. Biotechnol. 28:1057-1068, 2010.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 19
    • 77649243539 scopus 로고    scopus 로고
    • MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells
    • Qin, X., X. Wang, Y. Wang, Z. Tang, Q. Cui, J. Xi, Y. S. Li, S. Chien, and N. Wang. MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc. Natl Acad. Sci. U.S.A. 107:3240-3244, 2010.
    • (2010) Proc. Natl Acad. Sci. U.S.A. , vol.107 , pp. 3240-3244
    • Qin, X.1    Wang, X.2    Wang, Y.3    Tang, Z.4    Cui, Q.5    Xi, J.6    Li, Y.S.7    Chien, S.8    Wang, N.9
  • 20
    • 0037224722 scopus 로고    scopus 로고
    • DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
    • DOI 10.1038/ng1068
    • Robert, M. F., S. Morin, N. Beaulieu, F. Gauthier, I. C. Chute, A. Barsalou, and A. R. MacLeod. Dnmt1 is required to maintain CPG methylation and aberrant gene silencing in human cancer cells. Nat. Genet. 33:61-65, 2003. (Pubitemid 36068683)
    • (2003) Nature Genetics , vol.33 , Issue.1 , pp. 61-65
    • Robert, M.-F.1    Morin, S.2    Beaulieu, N.3    Gauthier, F.4    Chute, I.C.5    Barsalou, A.6    MacLeod, A.R.7
  • 22
    • 79955055958 scopus 로고    scopus 로고
    • Epigenetics in cardiovascular disease
    • Shirodkar, A. V., and P. A. Marsden. Epigenetics in cardiovascular disease. Curr. Opin. Cardiol. 26:209-215, 2011.
    • (2011) Curr. Opin. Cardiol. , vol.26 , pp. 209-215
    • Shirodkar, A.V.1    Marsden, P.A.2
  • 27
    • 84880272931 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell turnover by endothelial cellsecreted microrna-126: Role of shear stress
    • Zhou, J., Y. S. Li, P. Nguyen, K. C. Wang, A. Weiss, Y. C. Kuo, J. J. Chiu, J. Y. Shyy, and S. Chien. Regulation of vascular smooth muscle cell turnover by endothelial cellsecreted microrna-126: role of shear stress. Circ. Res. 113:40-51, 2013.
    • (2013) Circ. Res. , vol.113 , pp. 40-51
    • Zhou, J.1    Li, Y.S.2    Nguyen, P.3    Wang, K.C.4    Weiss, A.5    Kuo, Y.C.6    Chiu, J.J.7    Shyy, J.Y.8    Chien, S.9
  • 28
    • 79959973595 scopus 로고    scopus 로고
    • MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation
    • Zhou, J., K. C. Wang, W. Wu, S. Subramaniam, J. Y. Shyy, J. J. Chiu, J. Y. Li, and S. Chien. MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc. Natl Acad. Sci. U.S.A. 108:10355-10360, 2011.
    • (2011) Proc. Natl Acad. Sci. U.S.A. , vol.108 , pp. 10355-10360
    • Zhou, J.1    Wang, K.C.2    Wu, W.3    Subramaniam, S.4    Shyy, J.Y.5    Chiu, J.J.6    Li, J.Y.7    Chien, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.