메뉴 건너뛰기




Volumn 4, Issue , 2013, Pages

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; DICER; MATRIX METALLOPROTEINASE; MESSENGER RNA; MICRORNA; MICRORNA 10A; MICRORNA 195; MICRORNA 205; MICRORNA 223; MICRORNA 27B; MICRORNA 29B; MICRORNA 320; MICRORNA 330; MICRORNA 712; RIBOSOME RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; MIRN712 MICRORNA, HUMAN; MIRN712 MICRORNA, MOUSE; TIMP3 PROTEIN, HUMAN;

EID: 84897112063     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4000     Document Type: Article
Times cited : (204)

References (60)
  • 1
    • 77957935751 scopus 로고    scopus 로고
    • Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow
    • Ni, C. W. et al. Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow. Blood 116, e66-e73 (2010).
    • (2010) Blood , vol.116 , pp. e66-e73
    • Ni, C.W.1
  • 2
    • 40749113168 scopus 로고    scopus 로고
    • Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells
    • Berk, B. C. Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells. Circulation 117, 1082-1089 (2008).
    • (2008) Circulation , vol.117 , pp. 1082-1089
    • Berk, B.C.1
  • 3
    • 0021966255 scopus 로고
    • Pulsatile flow and atherosclerosis in the human carotid bifurcation - Positive correlation between plaque location and low and oscillating shear-stress
    • Ku, D. N., Giddens, D. P., Zarins, C. K. & Glagov, S. Pulsatile flow and atherosclerosis in the human carotid bifurcation - positive correlation between plaque location and low and oscillating shear-stress. Arteriosclerosis 5, 293-302 (1985).
    • (1985) Arteriosclerosis , vol.5 , pp. 293-302
    • Ku, D.N.1    Giddens, D.P.2    Zarins, C.K.3    Glagov, S.4
  • 4
    • 0035979179 scopus 로고    scopus 로고
    • DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells
    • McCormick, S. M. et al. DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells. Proc. Natl Acad. Sci. USA 98, 8955-8960 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 8955-8960
    • McCormick, S.M.1
  • 5
    • 78751652828 scopus 로고    scopus 로고
    • Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives
    • Chiu, J. J. & Chien, S. Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol. Rev. 91, 327-387 (2011).
    • (2011) Physiol. Rev. , vol.91 , pp. 327-387
    • Chiu, J.J.1    Chien, S.2
  • 6
    • 58049213790 scopus 로고    scopus 로고
    • Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
    • Davies, P. F. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat. Clin. Pract. Cardiovasc. Med. 6, 16-26 (2009).
    • (2009) Nat. Clin. Pract. Cardiovasc. Med. , vol.6 , pp. 16-26
    • Davies, P.F.1
  • 7
    • 25144510997 scopus 로고    scopus 로고
    • A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
    • Tzima, E. et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437, 426-431 (2005).
    • (2005) Nature , vol.437 , pp. 426-431
    • Tzima, E.1
  • 8
    • 10744233033 scopus 로고    scopus 로고
    • Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta
    • Passerini, A. G. et al. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc. Natl Acad. Sci. USA 101, 2482-2487 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2482-2487
    • Passerini, A.G.1
  • 9
    • 6944244066 scopus 로고    scopus 로고
    • Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature
    • Dai, G. et al. Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc. Natl Acad. Sci. USA 101, 14871-14876 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 14871-14876
    • Dai, G.1
  • 10
    • 70349626069 scopus 로고    scopus 로고
    • Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis
    • Nam, D. et al. Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. Am. J. Physiol. Heart Circ. Physiol. 297, H1535-H1543 (2009).
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.297 , pp. H1535-H1543
    • Nam, D.1
  • 11
    • 0042178259 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc
    • Magid, R., Murphy, T. J. & Galis, Z. S. Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc. J. Biol. Chem. 278, 32994-32999 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 32994-32999
    • Magid, R.1    Murphy, T.J.2    Galis, Z.S.3
  • 12
    • 34250774463 scopus 로고    scopus 로고
    • Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: Molecular, cellular, and vascular behavior
    • Chatzizisis, Y. S. et al. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J. Am. Coll. Cardiol. 49, 2379-2393 (2007).
    • (2007) J. Am. Coll. Cardiol. , vol.49 , pp. 2379-2393
    • Chatzizisis, Y.S.1
  • 13
    • 77951686244 scopus 로고    scopus 로고
    • Extracellular matrix, inflammation, and the angiogenic response
    • Arroyo, A. G. & Iruela-Arispe, M. L. Extracellular matrix, inflammation, and the angiogenic response. Cardiovasc. Res. 86, 226-235 (2010).
    • (2010) Cardiovasc. Res. , vol.86 , pp. 226-235
    • Arroyo, A.G.1    Iruela-Arispe, M.L.2
  • 14
    • 79955759844 scopus 로고    scopus 로고
    • MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells
    • Ni, C. W., Qiu, H. & Jo, H. MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 300, H1762-H1769 (2011).
    • (2011) Am. J. Physiol. Heart Circ. Physiol. , vol.300 , pp. H1762-H1769
    • Ni, C.W.1    Qiu, H.2    Jo, H.3
  • 15
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory, R. I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 (2004).
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1
  • 16
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee, Y. et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1
  • 17
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the microprocessor complex
    • Denli, A. M., Tops, B. B., Plasterk, R. H., Ketting, R. F. & Hannon, G. J. Processing of primary microRNAs by the microprocessor complex. Nature 432, 231-235 (2004).
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 19
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby, J. G., Jan, C. H. & Bartel, D. P. Intronic microRNA precursors that bypass Drosha processing. Nature 448, 83-86 (2007).
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 20
    • 0034548433 scopus 로고    scopus 로고
    • The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5′ - > 3′ exonucleases
    • Geerlings, T. H., Vos, J. C. & Raue, H. A. The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5′ - > 3′ exonucleases. RNA 6, 1698-1703 (2000).
    • (2000) RNA , vol.6 , pp. 1698-1703
    • Geerlings, T.H.1    Vos, J.C.2    Raue, H.A.3
  • 21
    • 79958033251 scopus 로고    scopus 로고
    • MiRPara: A SVM-based software tool for prediction of most probable microRNA coding regions in genome scale sequences
    • Wu, Y., Wei, B., Liu, H., Li, T. & Rayner, S. MiRPara: a SVM-based software tool for prediction of most probable microRNA coding regions in genome scale sequences. BMC Bioinformatics 12, 107 (2011).
    • (2011) BMC Bioinformatics , vol.12 , pp. 107
    • Wu, Y.1    Wei, B.2    Liu, H.3    Li, T.4    Rayner, S.5
  • 22
    • 44349119866 scopus 로고    scopus 로고
    • Mireval: A web tool for simple microRNA prediction in genome sequences
    • Ritchie, W., Theodule, F. X. & Gautheret, D. Mireval: a web tool for simple microRNA prediction in genome sequences. Bioinformatics 24, 1394-1396 (2008).
    • (2008) Bioinformatics , vol.24 , pp. 1394-1396
    • Ritchie, W.1    Theodule, F.X.2    Gautheret, D.3
  • 23
    • 4444380994 scopus 로고    scopus 로고
    • TIMP3 checks inflammation
    • Black, R. A. TIMP3 checks inflammation. Nat. Genet. 36, 934-935 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 934-935
    • Black, R.A.1
  • 24
    • 80052735881 scopus 로고    scopus 로고
    • Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy
    • George, S. J. et al. Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation 124, S135-S142 (2011).
    • (2011) Circulation , vol.124 , pp. S135-S142
    • George, S.J.1
  • 25
    • 31044437380 scopus 로고    scopus 로고
    • Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha
    • Federici, M. et al. Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha. J. Clin. Invest. 115, 3494-3505 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 3494-3505
    • Federici, M.1
  • 26
    • 79251494127 scopus 로고    scopus 로고
    • Glycosaminoglycans as key molecules in atherosclerosis: The role of versican and hyaluronan
    • Karangelis, D. E. et al. Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan. Curr. Med. Chem. 17, 4018-4026 (2010).
    • (2010) Curr. Med. Chem. , vol.17 , pp. 4018-4026
    • Karangelis, D.E.1
  • 27
    • 19944429537 scopus 로고    scopus 로고
    • Role of ADAMTS-1 in atherosclerosis: Remodeling of carotid artery, immunohistochemistry, and proteolysis of versican
    • Jonsson-Rylander, A. C. et al. Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican. Arterioscler. Thromb. Vasc. Biol. 25, 180-185 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 180-185
    • Jonsson-Rylander, A.C.1
  • 28
    • 83655167191 scopus 로고    scopus 로고
    • Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice
    • Casagrande, V. et al. Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice. Arterioscler. Thromb. Vasc. Biol. 32, 74-81 (2012).
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 74-81
    • Casagrande, V.1
  • 29
    • 0030175509 scopus 로고    scopus 로고
    • A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries
    • Lei, M., Kleinstreuer, C. & Truskey, G. A. A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries. Med. Eng. Phys. 18, 326-332 (1996).
    • (1996) Med. Eng. Phys. , vol.18 , pp. 326-332
    • Lei, M.1    Kleinstreuer, C.2    Truskey, G.A.3
  • 30
    • 0028157367 scopus 로고
    • Characterization of sites with elevated LDL permeability at intercostal, celiac, and iliac branches of the normal rabbit aorta
    • Herrmann, R. A., Malinauskas, R. A. & Truskey, G. A. Characterization of sites with elevated LDL permeability at intercostal, celiac, and iliac branches of the normal rabbit aorta. Arterioscler. Thromb. 14, 313-323 (1994).
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 313-323
    • Herrmann, R.A.1    Malinauskas, R.A.2    Truskey, G.A.3
  • 31
    • 80052970775 scopus 로고    scopus 로고
    • Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice
    • Park, J. G. et al. Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. Circ. Res. 109, 739-749 (2011).
    • (2011) Circ. Res. , vol.109 , pp. 739-749
    • Park, J.G.1
  • 32
    • 67349271005 scopus 로고    scopus 로고
    • ITS2 sequence-structure analysis in phylogenetics: A how-to manual for molecular systematics
    • Schultz, J. & Wolf, M. ITS2 sequence-structure analysis in phylogenetics: a how-to manual for molecular systematics. Mol. Phylogenet. Evol. 52, 520-523 (2009).
    • (2009) Mol. Phylogenet. Evol. , vol.52 , pp. 520-523
    • Schultz, J.1    Wolf, M.2
  • 33
    • 0033567356 scopus 로고    scopus 로고
    • Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins
    • Moy, T. I. & Silver, P. A. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes Dev. 13, 2118-2133 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 2118-2133
    • Moy, T.I.1    Silver, P.A.2
  • 34
    • 70349633646 scopus 로고    scopus 로고
    • TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1
    • Cardellini, M. et al. TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. Diabetes 58, 2396-2401 (2009).
    • (2009) Diabetes , vol.58 , pp. 2396-2401
    • Cardellini, M.1
  • 35
    • 2442681602 scopus 로고    scopus 로고
    • Proteoglycans in atherosclerosis and restenosis: Key roles for versican
    • Wight, T. N. & Merrilees, M. J. Proteoglycans in atherosclerosis and restenosis: key roles for versican. Circ. Res. 94, 1158-1167 (2004).
    • (2004) Circ. Res. , vol.94 , pp. 1158-1167
    • Wight, T.N.1    Merrilees, M.J.2
  • 36
    • 45149112724 scopus 로고    scopus 로고
    • Role of ADAMs in endothelial cell permeability: Cadherin shedding and leukocyte rolling
    • Ponnuchamy, B. & Khalil, R. A. Role of ADAMs in endothelial cell permeability: cadherin shedding and leukocyte rolling. Circ. Res. 102, 1139-1142 (2008).
    • (2008) Circ. Res. , vol.102 , pp. 1139-1142
    • Ponnuchamy, B.1    Khalil, R.A.2
  • 37
    • 84867643743 scopus 로고    scopus 로고
    • MicroRNA-101 mediates the suppressive effect of laminar shear stress on mTOR expression in vascular endothelial cells
    • Chen, K. et al. MicroRNA-101 mediates the suppressive effect of laminar shear stress on mTOR expression in vascular endothelial cells. Biochem. Biophys. Res. Commun. 427, 138-142 (2012).
    • (2012) Biochem. Biophys. Res. Commun. , vol.427 , pp. 138-142
    • Chen, K.1
  • 38
    • 77649240980 scopus 로고    scopus 로고
    • Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth
    • Wang, K. C. et al. Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth. Proc. Natl Acad. Sci. USA 107, 3234-3239 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 3234-3239
    • Wang, K.C.1
  • 39
    • 77649243539 scopus 로고    scopus 로고
    • MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells
    • Qin, X. et al. MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc. Natl Acad. Sci. 107, 3240-3244 (2010).
    • (2010) Proc. Natl Acad. Sci. , vol.107 , pp. 3240-3244
    • Qin, X.1
  • 40
    • 77949488939 scopus 로고    scopus 로고
    • MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity
    • Weber, M., Baker, M. B., Moore, J. P. & Searles, C. D. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity. Biochem. Biophys. Res. Commun. 393, 643-648 (2010).
    • (2010) Biochem. Biophys. Res. Commun. , vol.393 , pp. 643-648
    • Weber, M.1    Baker, M.B.2    Moore, J.P.3    Searles, C.D.4
  • 41
    • 77955795714 scopus 로고    scopus 로고
    • MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro
    • Fang, Y., Shi, C., Manduchi, E., Civelek, M. & Davies, P. F. MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro. Proc. Natl Acad. Sci. 107, 13450-13455 (2010).
    • (2010) Proc. Natl Acad. Sci. , vol.107 , pp. 13450-13455
    • Fang, Y.1    Shi, C.2    Manduchi, E.3    Civelek, M.4    Davies, P.F.5
  • 42
    • 84885176963 scopus 로고    scopus 로고
    • Mechanosensitive microRNAs-role in endothelial responses to shear stress and redox state
    • Marin, T. et al. Mechanosensitive microRNAs-role in endothelial responses to shear stress and redox state. Free Radic. Biol. Med. 64, 61-68 (2013).
    • (2013) Free Radic. Biol. Med. , vol.64 , pp. 61-68
    • Marin, T.1
  • 43
    • 79959973595 scopus 로고    scopus 로고
    • MicroRNA-21 targets peroxisome proliferators-activated receptor-a in an autoregulatory loop to modulate flow-induced endothelial inflammation
    • Zhou, J. et al. MicroRNA-21 targets peroxisome proliferators-activated receptor-a in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc. Natl Acad. Sci. 108, 10355-10360 (2011).
    • (2011) Proc. Natl Acad. Sci. , vol.108 , pp. 10355-10360
    • Zhou, J.1
  • 44
    • 80051546031 scopus 로고    scopus 로고
    • Flow-dependent regulation of Krüppel-like factor 2 is mediated by microRNA-92a
    • Wu, W. et al. Flow-dependent regulation of Krüppel-like factor 2 is mediated by microRNA-92a. Circulation 124, 633-641 (2011).
    • (2011) Circulation , vol.124 , pp. 633-641
    • Wu, W.1
  • 46
    • 84857708170 scopus 로고    scopus 로고
    • Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
    • Hergenreider, E. et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat. Cell. Biol. 14, 249-256 (2012).
    • (2012) Nat. Cell. Biol. , vol.14 , pp. 249-256
    • Hergenreider, E.1
  • 47
    • 84859892863 scopus 로고    scopus 로고
    • MicroRNA profiling: Approaches and considerations
    • Pritchard, C. C., Cheng, H. H. & Tewari, M. MicroRNA profiling: approaches and considerations. Nat. Rev. Genet. 13, 358-369 (2012).
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 358-369
    • Pritchard, C.C.1    Cheng, H.H.2    Tewari, M.3
  • 48
    • 80055102945 scopus 로고    scopus 로고
    • A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium
    • Nam, D. et al. A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium. J. Vis. Exp. 40, e1861 (2010).
    • (2010) J. Vis. Exp. , vol.40
    • Nam, D.1
  • 49
    • 0032521142 scopus 로고    scopus 로고
    • Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis
    • Baker, A. H., Zaltsman, A. B., George, S. J. & Newby, A. C. Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis. J. Clin. Invest. 101, 1478-1487 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 1478-1487
    • Baker, A.H.1    Zaltsman, A.B.2    George, S.J.3    Newby, A.C.4
  • 50
    • 0029926891 scopus 로고    scopus 로고
    • Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in mice
    • Hnatowich, D. J. et al. Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in mice. J. Pharmacol. Exp. Ther. 276, 326-334 (1996).
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 326-334
    • Hnatowich, D.J.1
  • 51
    • 79959746256 scopus 로고    scopus 로고
    • Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow
    • Li, L., Chen, W., Rezvan, A., Jo, H. & Harrison, D. G. Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow. Arterioscler. Thromb. Vasc. Biol. 31, 1547-1554 (2011).
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1547-1554
    • Li, L.1    Chen, W.2    Rezvan, A.3    Jo, H.4    Harrison, D.G.5
  • 52
    • 34250777057 scopus 로고    scopus 로고
    • Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections
    • Obernosterer, G., Martinez, J. & Alenius, M. Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat. Protoc. 2, 1508-1514 (2007).
    • (2007) Nat. Protoc. , vol.2 , pp. 1508-1514
    • Obernosterer, G.1    Martinez, J.2    Alenius, M.3
  • 54
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for Annotation, Visualization, and Integrated Discovery
    • Dennis, Jr. G. et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, P3 (2003).
    • (2003) Genome Biol. , vol.4 , pp. P3
    • Dennis, G.1
  • 55
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto encyclopedia of genes and genomes
    • Kanehisa, M. & Goto, S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28, 27-30 (2000).
    • (2000) Nucleic Acids Res. , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 56
    • 46049087782 scopus 로고    scopus 로고
    • The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation
    • Wingender, E. The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation. Brief Bioinform. 9, 326-332 (2008).
    • (2008) Brief Bioinform. , vol.9 , pp. 326-332
    • Wingender, E.1
  • 58
    • 0043234315 scopus 로고    scopus 로고
    • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response
    • Sorescu, G. P. et al. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. J. Biol. Chem. 278, 31128-31135 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 31128-31135
    • Sorescu, G.P.1
  • 59
    • 85027934166 scopus 로고    scopus 로고
    • Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells
    • Williams, H. C. et al. Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells. Circ. Res. 111, 56-65 (2012).
    • (2012) Circ. Res. , vol.111 , pp. 56-65
    • Williams, H.C.1
  • 60
    • 39549110203 scopus 로고    scopus 로고
    • MicroRNA detection by northern blotting using locked nucleic acid probes
    • Varallyay, E., Burgyan, J. & Havelda, Z. MicroRNA detection by northern blotting using locked nucleic acid probes. Nat. Protoc. 3, 190-196 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 190-196
    • Varallyay, E.1    Burgyan, J.2    Havelda, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.