TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex

Molecular Immunology

Volumn 68, Issue 2, 2015, Pages 546-557

  Shi, Jian hong ^a   Sun, Shao Cong ^b,c  

^a HEBEI UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

CARMA1; Glutamine; mTORC1; NF B; T cell activation; T cell tolerance; TCR signaling

Indexed keywords

CD28 ANTIGEN; CYTOKINE; DEUBIQUITINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE EPSILON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 2; INTERLEUKIN 7; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN BCL 10; PROTEIN BCL 3; PROTEIN CARMA1; PROTEIN KINASE C THETA; PROTEIN MALT1; PROTEIN SERINE THREONINE KINASE; PROTEIN TBK1; SCAFFOLD PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UBIQUITIN CONJUGATING ENZYME 13; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARD11 PROTEIN, HUMAN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; GUANYLATE CYCLASE; LYMPHOCYTE ANTIGEN RECEPTOR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

ALLERGIC AIRWAY INFLAMMATION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD8+ T LYMPHOCYTE; CELL MEMBRANE; CYTOPLASM; CYTOTOXIC T LYMPHOCYTE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HOMEOSTASIS; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INFLAMMATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC INFILTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; TH2 CELL; UBIQUITINATION; ANIMAL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM;

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; GUANYLATE CYCLASE; HUMANS; LYMPHOCYTE ACTIVATION; MULTIPROTEIN COMPLEXES; NF-KAPPA B; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84949110031     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.07.024     Document Type: Article

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