Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

Journal of Immunology

Volumn 194, Issue 8, 2015, Pages 3723-3734

  Bornancin, Frédéric ^a   Renner, Florian ^a   Touil, Ratiba ^a   Sic, Heiko ^a   Kolb, Yeter ^a   Touil Allaoui, Ismahane ^a   Rush, James S ^a   Smith, Paul A ^a   Bigaud, Marc ^a   Junker Walker, Ursula ^a   Burkhart, Christoph ^a   Dawson, Janet ^a   Niwa, Satoru ^a   Katopodis, Andreas ^a   Nuesslein Hildesheim, Barbara ^a   Weckbecker, Gisbert ^a   Zenke, Gerhard ^a   Kinzel, Bernd ^a   Traggiai, Elisabetta ^a   Brenner, Dirk ^b,c   Brüstle, Anne ^b,d   Paul, Michael St ^b   Zamurovic, Natasa ^a   McCoy, Kathy D ^e   Rolink, Antonius ^f   Régnier, Catherine H ^a   Mak, Tak W ^b   Ohashi, Pamela S ^b   Patel, Dhavalkumar D ^a   Calzascia, Thomas ^a   more..

^a NOVARTIS PHARMA AG   (Switzerland)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^d Australian National University   (Australia)

^e UNIVERSITY OF BERN   (Switzerland)

^f UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 2; MALT1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IL10 PROTEIN, MOUSE; IMMUNOGLOBULIN G; INTERLEUKIN 10; MALT1 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INACTIVATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; GENE SILENCING; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; WILD TYPE; ANIMAL; CELL DIFFERENTIATION; CELL PROLIFERATION; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; B-LYMPHOCYTES, REGULATORY; CASPASES; CELL DIFFERENTIATION; CELL PROLIFERATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-2; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS;

EID: 84927603501     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402254     Document Type: Article

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