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Volumn 110, Issue 52, 2013, Pages 21107-21112

TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOTOXIN BETA RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRANSCRIPTION FACTOR RELB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3;

EID: 84891353142     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1314859111     Document Type: Article
Times cited : (30)

References (41)
  • 1
    • 36448949476 scopus 로고    scopus 로고
    • Generating intrathymic microenvironments to establish T-cell tolerance
    • Anderson G, Lane PJ, Jenkinson EJ (2007) Generating intrathymic microenvironments to establish T-cell tolerance. Nat Rev Immunol 7(12): 954-963.
    • (2007) Nat Rev Immunol , vol.7 , Issue.12 , pp. 954-963
    • Anderson, G.1    Lane, P.J.2    Jenkinson, E.J.3
  • 5
    • 0025885218 scopus 로고
    • Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: Evidence that receptorbearing lymphocytes influence maturation of the thymic microenvironment
    • Shores EW, Van Ewijk W, Singer A (1991) Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: Evidence that receptorbearing lymphocytes influence maturation of the thymic microenvironment. Eur J Immunol 21(7): 1657-1661.
    • (1991) Eur J Immunol , vol.21 , Issue.7 , pp. 1657-1661
    • Shores, E.W.1    Van Ewijk, W.2    Singer, A.3
  • 7
    • 0026749048 scopus 로고
    • Growth of epithelial cells in the thymic medulla is under the control of mature T cells
    • Surh CD, Ernst B, Sprent J (1992) Growth of epithelial cells in the thymic medulla is under the control of mature T cells. J Exp Med 176(2): 611-616.
    • (1992) J Exp Med , vol.176 , Issue.2 , pp. 611-616
    • Surh, C.D.1    Ernst, B.2    Sprent, J.3
  • 8
    • 51349092893 scopus 로고    scopus 로고
    • The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator
    • Hikosaka Y, et al. (2008) The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity 29(3): 438-450.
    • (2008) Immunity , vol.29 , Issue.3 , pp. 438-450
    • Hikosaka, Y.1
  • 9
    • 51349101423 scopus 로고    scopus 로고
    • Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity
    • Irla M, et al. (2008) Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity. Immunity 29(3): 451-463.
    • (2008) Immunity , vol.29 , Issue.3 , pp. 451-463
    • Irla, M.1
  • 10
    • 78049496246 scopus 로고    scopus 로고
    • Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells
    • White AJ, et al. (2010) Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells. J Immunol 185(8): 4769-4776.
    • (2010) J Immunol , vol.185 , Issue.8 , pp. 4769-4776
    • White, A.J.1
  • 11
    • 44849090702 scopus 로고    scopus 로고
    • Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
    • White AJ, et al. (2008) Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol 38(4): 942-947.
    • (2008) Eur J Immunol , vol.38 , Issue.4 , pp. 942-947
    • White, A.J.1
  • 12
    • 0028952482 scopus 로고
    • Expression of relB is required for the development of thymic medulla and dendritic cells
    • Burkly L, et al. (1995) Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373(6514): 531-536.
    • (1995) Nature , vol.373 , Issue.6514 , pp. 531-536
    • Burkly, L.1
  • 13
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family
    • Weih F, et al. (1995) Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell 80(2): 331-340.
    • (1995) Cell , vol.80 , Issue.2 , pp. 331-340
    • Weih, F.1
  • 14
    • 33846237346 scopus 로고    scopus 로고
    • Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells
    • Lomada D, Liu B, Coghlan L, Hu Y, Richie ER (2007) Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. J Immunol 178(2): 829-837.
    • (2007) J Immunol , vol.178 , Issue.2 , pp. 829-837
    • Lomada, D.1    Liu, B.2    Coghlan, L.3    Hu, Y.4    Richie, E.R.5
  • 15
    • 33646055527 scopus 로고    scopus 로고
    • Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance
    • Kinoshita D, et al. (2006) Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance. J Immunol 176(7): 3995-4002.
    • (2006) J Immunol , vol.176 , Issue.7 , pp. 3995-4002
    • Kinoshita, D.1
  • 16
    • 10744226628 scopus 로고    scopus 로고
    • NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner
    • Kajiura F, et al. (2004) NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. J Immunol 172(4): 2067-2075.
    • (2004) J Immunol , vol.172 , Issue.4 , pp. 2067-2075
    • Kajiura, F.1
  • 17
    • 56349164232 scopus 로고    scopus 로고
    • Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
    • Vallabhapurapu S, et al. (2008) Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol 9(12): 1364-1370.
    • (2008) Nat Immunol , vol.9 , Issue.12 , pp. 1364-1370
    • Vallabhapurapu, S.1
  • 18
    • 33750494135 scopus 로고    scopus 로고
    • Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
    • He JQ, et al. (2006) Rescue of TRAF3-null mice by p100 NF-kappa B deficiency. J Exp Med 203(11): 2413-2418.
    • (2006) J Exp Med , vol.203 , Issue.11 , pp. 2413-2418
    • He, J.Q.1
  • 19
    • 34548014506 scopus 로고    scopus 로고
    • Tumor necrosis factor receptorassociated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs
    • Xie P, Stunz LL, Larison KD, Yang B, Bishop GA (2007) Tumor necrosis factor receptorassociated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity 27(2): 253-267.
    • (2007) Immunity , vol.27 , Issue.2 , pp. 253-267
    • Xie, P.1    Stunz, L.L.2    Larison, K.D.3    Yang, B.4    Bishop, G.A.5
  • 20
    • 64849101655 scopus 로고    scopus 로고
    • Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function
    • Zuklys S, et al. (2009) Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol 182(5): 2997-3007.
    • (2009) J Immunol , vol.182 , Issue.5 , pp. 2997-3007
    • Zuklys, S.1
  • 22
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski J, Schulte A, Kyewski B, Klein L (2001) Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2(11): 1032-1039.
    • (2001) Nat Immunol , vol.2 , Issue.11 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 23
    • 34250336454 scopus 로고    scopus 로고
    • RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
    • Rossi SW, et al. (2007) RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med 204(6): 1267-1272.
    • (2007) J Exp Med , vol.204 , Issue.6 , pp. 1267-1272
    • Rossi, S.W.1
  • 24
    • 51349111243 scopus 로고    scopus 로고
    • The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
    • Akiyama T, et al. (2008) The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 29(3): 423-437.
    • (2008) Immunity , vol.29 , Issue.3 , pp. 423-437
    • Akiyama, T.1
  • 25
    • 0041884736 scopus 로고    scopus 로고
    • Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lymphoepithelial cross talk via LTbetaR
    • Boehm T, Scheu S, Pfeffer K, Bleul CC (2003) Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lymphoepithelial cross talk via LTbetaR. J Exp Med 198(5): 757-769.
    • (2003) J Exp Med , vol.198 , Issue.5 , pp. 757-769
    • Boehm, T.1    Scheu, S.2    Pfeffer, K.3    Bleul, C.C.4
  • 26
    • 84871127197 scopus 로고    scopus 로고
    • Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla
    • Desanti GE, et al. (2012) Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla. J Immunol 189(12): 5519-5526.
    • (2012) J Immunol , vol.189 , Issue.12 , pp. 5519-5526
    • Desanti, G.E.1
  • 27
    • 79955549011 scopus 로고    scopus 로고
    • Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma
    • Mouri Y, et al. (2011) Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. J Immunol 186(9): 5047-5057.
    • (2011) J Immunol , vol.186 , Issue.9 , pp. 5047-5057
    • Mouri, Y.1
  • 28
    • 84871661087 scopus 로고    scopus 로고
    • Antigen recognition by autoreactive CD4+ thymocytes drives homeostasis of the thymic medulla
    • Irla M, et al. (2012) Antigen recognition by autoreactive CD4+ thymocytes drives homeostasis of the thymic medulla. PLoS ONE 7(12):e52591.
    • (2012) PLoS ONE , vol.7 , Issue.12
    • Irla, M.1
  • 29
    • 0037107399 scopus 로고    scopus 로고
    • CD40 regulates the processing of NF-kappaB2 p100 to p52
    • Coope HJ, et al. (2002) CD40 regulates the processing of NF-kappaB2 p100 to p52. EMBO J 21(20): 5375-5385.
    • (2002) EMBO J , vol.21 , Issue.20 , pp. 5375-5385
    • Coope, H.J.1
  • 30
    • 0042386014 scopus 로고    scopus 로고
    • The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis
    • Novack DV, et al. (2003) The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis. J Exp Med 198(5): 771-781.
    • (2003) J Exp Med , vol.198 , Issue.5 , pp. 771-781
    • Novack, D.V.1
  • 31
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
    • Dejardin E, et al. (2002) The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 17(4): 525-535.
    • (2002) Immunity , vol.17 , Issue.4 , pp. 525-535
    • Dejardin, E.1
  • 32
    • 16444377660 scopus 로고    scopus 로고
    • Dependence of self-tolerance on TRAF6-directed development of thymic stroma
    • Akiyama T, et al. (2005) Dependence of self-tolerance on TRAF6-directed development of thymic stroma. Science 308(5719): 248-251.
    • (2005) Science , vol.308 , Issue.5719 , pp. 248-251
    • Akiyama, T.1
  • 33
    • 40249115896 scopus 로고    scopus 로고
    • TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor
    • Gardam S, Sierro F, Basten A, Mackay F, Brink R (2008) TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity 28(3): 391-401.
    • (2008) Immunity , vol.28 , Issue.3 , pp. 391-401
    • Gardam, S.1    Sierro, F.2    Basten, A.3    Mackay, F.4    Brink, R.5
  • 34
    • 84858795036 scopus 로고    scopus 로고
    • Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium
    • Roberts NA, et al. (2012) Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity 36(3): 427-437.
    • (2012) Immunity , vol.36 , Issue.3 , pp. 427-437
    • Roberts, N.A.1
  • 35
    • 0032127301 scopus 로고    scopus 로고
    • The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
    • Fütterer A, Mink K, Luz A, Kosco-Vilbois MH, Pfeffer K (1998) The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9(1): 59-70.
    • (1998) Immunity , vol.9 , Issue.1 , pp. 59-70
    • Fütterer, A.1    Mink, K.2    Luz, A.3    Kosco-Vilbois, M.H.4    Pfeffer, K.5
  • 36
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
    • Barnden MJ, Allison J, Heath WR, Carbone FR (1998) Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 76(1): 34-40.
    • (1998) Immunol Cell Biol , vol.76 , Issue.1 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4
  • 37
    • 0034718609 scopus 로고    scopus 로고
    • Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene
    • Kim N, Odgren PR, Kim DK, Marks SC, Jr., Choi Y (2000) Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene. Proc Natl Acad Sci USA 97(20): 10905-10910.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.20 , pp. 10905-10910
    • Kim, N.1    Odgren, P.R.2    Kim, D.K.3    Marks Jr., S.C.4    Choi, Y.5
  • 38
    • 0026613009 scopus 로고
    • Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells
    • Philpott KL, et al. (1992) Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science 256(5062): 1448-1452.
    • (1992) Science , vol.256 , Issue.5062 , pp. 1448-1452
    • Philpott, K.L.1
  • 39
    • 0003633755 scopus 로고
    • Committee on Care and Use of Laboratory Animals, (Natl Inst Health, Bethesda), DHHS Publ No (NIH) 85-23.
    • Committee on Care and Use of Laboratory Animals (1985) Guide for the Care and Use of Laboratory Animals (Natl Inst Health, Bethesda), DHHS Publ No (NIH) 85-23.
    • (1985) Guide for the Care and Use of Laboratory Animals
  • 40
    • 37049010471 scopus 로고    scopus 로고
    • Unbiased analysis, enrichment and purification of thymic stromal cells
    • Gray DH, et al. (2008) Unbiased analysis, enrichment and purification of thymic stromal cells. J Immunol Methods 329(1-2): 56-66.
    • (2008) J Immunol Methods , vol.329 , Issue.1-2 , pp. 56-66
    • Gray, D.H.1
  • 41
    • 44849114330 scopus 로고    scopus 로고
    • A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery
    • Hubert FX, et al. (2008) A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery. J Immunol 180(6): 3824-3832.
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 3824-3832
    • Hubert, F.X.1


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