Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

Journal of Biological Chemistry

Volumn 280, Issue 28, 2005, Pages 26089-26093

  Holz, Marina K ^a   Blenis, John ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; PHOSPHORS; SENSITIVITY ANALYSIS; SIGNALING; TUMORS;

CANCER CELLS; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); RAPAMYCIN-SENSITIVE MANNER; S6 KINASE;

ENZYMES;

MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RAPAMYCIN; RNA; S6 KINASE; S6 KINASE 1; SERINE PROTEINASE; SMALL INHIBITORY RNA; THREONINE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL FREE SYSTEM; CELL STRAIN; CELL STRAIN MCF 10A; CELL STRAIN MCF 7; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; GENE; GENE AMPLIFICATION; GENE INACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REGULATORY SEQUENCE; S6K1 GENE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALLELES; ANDROSTADIENES; CELL LINE; CELL LINE, TUMOR; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN; MODELS, BIOLOGICAL; PHORBOL ESTERS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, MESSENGER; RNA, SMALL INTERFERING; SERINE; SIGNAL TRANSDUCTION; SIROLIMUS; THREONINE; TIME FACTORS;

MAMMALIA;

EID: 22544455676     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504045200     Document Type: Article

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