POLKADOTS are foci of functional interactions in T-cell receptor-mediated signaling to NF-κB

Molecular Biology of the Cell

Volumn 17, Issue 5, 2006, Pages 2166-2176

  Rossman, Jeremy S ^a   Stoicheva, Natalia G ^a   Langel, Felicia D ^a   Patterson, George H ^b   Lippincott Schwartz, Jennifer ^b   Schaefer, Brian C ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OLIGOMER; PROTEIN BCL 10; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; FLUORESCENCE RESONANCE ENERGY TRANSFER; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CASPASES; CELLS, CULTURED; HUMANS; MICE; NEOPLASM PROTEINS; NF-KAPPA B; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 33745756507     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E05-10-0985     Document Type: Article

References (45)

1. Bertin, J. et al. (2000). CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B. J. Biol. Chem. 275, 41082-41086.
2. Bertin, J., Wang, L., Guo, Y., Jacobson, M. D., Poyet, J. L., Srinivasula, S. M., Merriam, S., DiStefano, P. S., and Alnemri, E. S. (2001). CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane- associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B. J. Biol. Chem. 276, 11877-11882.
3. Boothby, M. R., Mora, A. L., Scherer, D. C., Brockman, J. A., and Ballard, D. W. (1997). Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. J. Exp. Med. 185, 1897-1907.
4. Brossard, C, Feuillet, V., Schmitt, A., Randriamampita, C., Romao, M., Raposo, G., and Trautmann, A. (2005). Multifocal structure of the T cell-dendritic cell synapse. Eur. J. Immunol. 35, 1741-1753.
5. Bunnell, S. C., Hong, D. I., Kardon, J. R., Yamazaki, T., McGlade, C. J., Barr, V. A., and Samelson, L. E. (2002). T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J. Cell Biol. 158, 1263-1275.
6. Campi, G., Varma, R., and Dustin, M. L. (2005). Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202, 1031-1036.
7. Che, T., You, Y., Wang, D., Tanner, M. J., Dixit, V. M., and Lin, X. (2004). MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation. J. Biol. Chem. 279, 15870-15876.
8. Davis, M. M., Boniface, J. J., Reich, Z., Lyons, D., Hampl, J., Arden, B., and Chien, Y. (1998). Ligand recognition by alpha beta T cell receptors. Annu. Rev. Immunol. 16, 523-544.
9. Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. (2000). Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 203, 351-361.
10. Dittel, B. N., and Janeway, C. A., Jr. (2000). Differential sensitivity to mutations in a single peptide by two TCRs having identical beta-chains and closely related alpha-chains. J. Immunol. 265, 6334-6340.
11. Douglass, A. D., and Vale, R. D. (2005). Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 222, 937-950.
12. Gaide, O., Favier, B., Legler, D. F., Bonnet, D., Brissoni, B., Valitutti, S., Bron, C., Tschopp, J., and Thome, M. (2002). CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation. Nat. Immunol. 3, 836-843.
13. Ghosh, S., May, M. J., and Kopp, E. B. (1998). NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
14. Griesbeck, O., Baird, G. S., Campbell, R. E., Zacharias, D. A., and Tsien, R. Y. (2001). Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications. J. Biol. Chem. 276, 29188-29194.
15. Kara, H., Bakal, C., Wada, T., Bouchard, D., Rottapel, R., Saito, T., and Penninger, J. M. (2004). The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. J. Exp. Med. 200, 1167-1177.
16. Isakov, N., and Altman, A. (2002). PKC(theta) in T cell activation. Annu. Rev. Immunol. 20, 761-794.
17. Jacobelli, J., Andres, P. G., Boisvert, J., and Krummel, M. F. (2004). New views of the immunological synapse: variations in assembly and function. Curr. Opin. Immunol. 26, 345-352.
18. Karasawa, S., Araki, T., Nagai, T., Mizuno, H., and Miyawaki, A. (2004). Cyan-emitting and orange-emitting fluorescent proteins as a donor/acceptor pair for fluorescence resonance energy transfer. Biochem. J. 382, 307-312.
19. Karin, M., and Ben-Neriah, Y. (2000). Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18, 621-663.
20. Koseki, T., Inohara, N., Chen, S., Carrio, R., Merino, J., Hottiger, M. O., Nabel, G. J., and Nunez, G. (1999). CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. J. Biol. Chem. 274, 9955-9961.
21. Lanzavecchia, A., and Sallusto, F. (2002). Progressive differentiation and selection of the fittest in the immune response. Nat. Rev. Immunol. 2, 982-987.
22. Lee, K. Y., D'Acquisto, F., Hayden, M. S., Shim, J. H., and Ghosh, S. (2005). PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science 308, 114-118.
23. Lin, X., and Wang, D. (2004). The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Semin. Immunol. 26, 429-435.
24. Lucas, P. C., Yonezumi, M., Inohara, N., McAllister-Lucas, L. M., Abazeed, M. E., Chen, F. F., Yamaoka, S., Seto, M., and Nunez, G. (2001). Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J. Biol. Chem. 276, 19012-19019.
25. McAllister-Lucas, L. M. et al. (2001). Bimp1, a MAGUK family member linking PKC activation to Bcl10-mediated NF-kappaB induction. J. Biol. Chem. 276, 30589-30597.
26. Monks, C. R., Kupfer, H., Tamir, I., Barlow, A., and Kupfer, A. (1997). Selective modulation of PKC-theta during T-cell activation. Nature 385, 83-86.
27. Nel, A. E. (2002). T-cell activation through the antigen receptor. Part 1, signaling components, signaling pathways, and signal integration at the T-cell antigen receptor synapse. J. Allergy Clin. Immunol. 109, 758-770.
28. Patterson, G. H., and Lippincott-Schwartz, J. (2002). A photoactivatable GFP for selective photolabeling of proteins and cells. Science 297, 1873-1877.
29. Rizzo, M. A., Springer, G. H., Granada, B., and Piston, D. W. (2004). An improved cyan fluorescent protein variant useful for FRET. Nat. Biotechnol. 22, 445-449.
30. Ruefli-Brasse, A. A., Lee, W. P., Hurst, S., and Dixit, V. M. (2004). Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation. J. Biol. Chem. 279, 1570-1574.
31. Ruland, J. et al. (2001). Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell 104, 33-42.
32. Schaefer, B. C., Kappler, J. W., Kupfer, A., and Marrack, P. (2004). Complex and dynamic redistribution of NF-{kappa}B signaling intermediates in response to T cell receptor stimulation. Proc. Natl. Acad. Sci. USA 101, 1004-1009.
33. Schaefer, B. C., Mitchell, T. C., Kappler, J. W., and Marrack, P. (2001). A novel family of retroviral vectors for the rapid production of complex stable cell lines. Anal. Biochem. 297, 86-93.
34. Schaefer, B. C., Ware, M. F., Marrack, P., Fanger, G. R., Kappler, J. W., Johnson, G. L., and Monks, C. R. (1999). Live cell fluorescence imaging of T cell MEKK2, redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity 11, 411-421.
35. Scharschmidt, E., Wegener, E., Heissmeyer, V., Rao, A., and Krappmann, D. (2004). Degradation of Bcl10 induced by T-cell activation negatively regulates NE-kappaB signaling. Mol. Cell. Biol. 24, 3860-3873.
36. Sedwick, C. E., and Altman, A. (2004). Perspectives on PKCtheta in T cell activation. Mol. Immunol. 41, 675-686.
37. Siegel, R. M., Martin, D. A., Zheng, L., Ng, S. Y., Bertin, J., Cohen, J., and Lenardo, M. J. (1998). Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis. J. Cell Biol. 242, 1243-1253.
38. Sun, L., Deng, L., Ea, C. K., Xia, Z. P., and Chen, Z. J. (2004). The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol. Cell 14, 289-301.
39. Truong, K., and Ikura, M. (2001). The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo. Curr. Opin. Struct. Biol. 22, 573-578.
40. Uren, A. G., O'Rourke, K., Aravind, L. A., Pisabarro, M. T., Seshagiri, S., Koonin, E.V., and Dixit, V. M. (2000). Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol. Cell 6, 961-967.
41. Villalba, M., Coudronniere, N., Deckert, M., Teixeiro, E., Mas, P., and Altman, A. (2000). A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation. Immunity 12, 151-160.
42. Xia, Z., and Liu, Y. (2001). Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes. Biophys. J. 81, 2395-2402.
43. Yokosuka, T., Sakata-Sogawa, K., Kobayashi, W., Hiroshima, M., Hashimoto-Tane, A., Tokunaga, M., Dustin, M. L., and Saito, T. (2005). Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat. Immunol. 6, 1253-1262.
44. Zacharias, D. A., Violin, J. D., Newton, A. C., and Tsien, R. Y. (2002). Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 296, 913-916.
45. Zhou, H., Wertz, I., O'Rourke, K., Ultsch, M., Seshagiri, S., Eby, M., Xiao, W., and Dixit, V. M. (2004). Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature 427, 167-171.