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Volumn 946, Issue , 2012, Pages 207-221

Nuclear factor-κB in immunity and inflammation: The Treg and Th17 connection

Author keywords

c Rel; Inflammation; NF B; Th17; Treg

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELA;

EID: 80555126026     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0106-3_12     Document Type: Article
Times cited : (69)

References (88)
  • 1
    • 0027220683 scopus 로고
    • NF-kappa B-like factors in the murine brain developmentally-regulated and tissue-specific expression
    • Bakalkin, G., Yakovleva, T., and Terenius, L.1993) NF-kappa B-like factors in the murine brain. Developmentally-regulated and tissue-specific expression. Brain Research Molecular Brain Research 20, 137-146.
    • (1993) Brain Research Molecular Brain Research , vol.20 , pp. 137-146
    • Bakalkin, G.1    Yakovleva, T.2    Terenius, L.3
  • 2
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes, P. J., and Karin, M.1997) Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. New England Journal of Medicine 336, 1066-1071.
    • (1997) New England Journal of Medicine , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 3
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alphainduced cell death
    • Beg, A. A., and Baltimore, D.1996) An essential role for NF-kappaB in preventing TNF-alphainduced cell death. Science 274, 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 4
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
    • Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S., and Baltimore, D.1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376, 167-170.
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 6
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., and Kuchroo, V. K.2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 8
    • 0023137250 scopus 로고
    • Detection of c-rel-related transcripts in mouse hematopoietic tissues fractionated lymphocyte populations and cell lines
    • Brownell, E., Mathieson, B., Young, H. A., Keller, J., Ihle, J. N., and Rice, N. R.1987) Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines. Molecular & Cellular Biology 7, 1304-1309.
    • (1987) Molecular & Cellular Biology , vol.7 , pp. 1304-1309
    • Brownell, E.1    Mathieson, B.2    Young, H.A.3    Keller, J.4    Ihle, J.N.5    Rice, N.R.6
  • 9
    • 0025184764 scopus 로고
    • The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain
    • Bull, P., Morley, K. L., Hoekstra, M. F., Hunter, T., and Verma, I. M.1990) The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Molecular & Cellular Biology 10, 5473-5485.
    • (1990) Molecular & Cellular Biology , vol.10 , pp. 5473-5485
    • Bull, P.1    Morley, K.L.2    Hoekstra, M.F.3    Hunter, T.4    Verma, I.M.5
  • 10
    • 34249799899 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel
    • Bunting, K., Rao, S., Hardy, K., Woltring, D., Denyer, G. S., Wang, J., Gerondakis, S., and Shannon, M. F.2007) Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel. Journal of Immunology 178, 7097-7109.
    • (2007) Journal of Immunology , vol.178 , pp. 7097-7109
    • Bunting, K.1    Rao, S.2    Hardy, K.3    Woltring, D.4    Denyer, G.S.5    Wang, J.6    Gerondakis, S.7    Shannon, M.F.8
  • 12
    • 33845947424 scopus 로고    scopus 로고
    • Essential roles of c-rel in toll-like receptor-induced interleukin-23 p19 gene expression in dendritic cells
    • Carmody, R. J., Ruan, Q., Liou, H.-C., and Chen, Y. H.2007a) Essential roles of c-Rel in Toll-like receptor-induced interleukin-23 p19 gene expression in dendritic cells. Journal of Immunology 178, 186-191.
    • (2007) Journal of Immunology , vol.178 , pp. 186-191
    • Carmody, R.J.1    Ruan, Q.2    Liou, H.-C.3    Chen, Y.H.4
  • 13
    • 33845947424 scopus 로고    scopus 로고
    • Essential roles of c-rel in tlrinduced il-23 p19 gene expression in dendritic cells
    • Carmody, R. J., Ruan, Q., Liou, H. C., and Chen, Y. H.2007b) Essential roles of c-Rel in TLRinduced IL-23 p19 gene expression in dendritic cells. Journal of Immunology 178, 186-191.
    • (2007) Journal of Immunology , vol.178 , pp. 186-191
    • Carmody, R.J.1    Ruan, Q.2    Liou, H.C.3    Chen, Y.H.4
  • 15
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen, Y., Kuchroo, V. K., Inobe, J., Hafler, D. A., and Weiner, H. L.1994) Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265, 1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 16
    • 33645959483 scopus 로고    scopus 로고
    • STAT3 and NF-kappaB signal pathway is required for IL- 23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonistdeficient mice
    • Cho, M. L., Kang, J. W., Moon, Y. M., Nam, H. J., Jhun, J. Y., Heo, S. B., Jin, H. T., Min, S. Y., Ju, J. H., Park, K. S., et al.2006) STAT3 and NF-kappaB signal pathway is required for IL- 23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonistdeficient mice. Journal of Immunology 176, 5652-5661.
    • (2006) Journal of Immunology , vol.176 , pp. 5652-5661
    • Cho, M.L.1    Kang, J.W.2    Moon, Y.M.3    Nam, H.J.4    Jhun, J.Y.5    Heo, S.B.6    Jin, H.T.7    Min, S.Y.8    Ju, J.H.9    Park, K.S.10
  • 18
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua, D. J., Sherlock, J., Chen, Y., Murphy, C. A., Joyce, B., Seymour, B., Lucian, L., To, W., Kwan, S., Churakova, T., et al.2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421, 744-748.
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3    Murphy, C.A.4    Joyce, B.5    Seymour, B.6    Lucian, L.7    To, W.8    Kwan, S.9    Churakova, T.10
  • 20
    • 0030999057 scopus 로고    scopus 로고
    • NF-kappa B RelA-deficient lymphocytes: Normal development of T cells and B cells impaired production of IgA and IgG1 and reduced proliferative responses
    • Doi, T. S., Takahashi, T., Taguchi, O., Azuma, T., and Obata, Y.1997) NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. Journal of Experimental Medicine 185, 953-961.
    • (1997) Journal of Experimental Medicine , vol.185 , pp. 953-961
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3    Azuma, T.4    Obata, Y.5
  • 23
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot, J. D., and Rudensky, A. Y.2005) A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nature Immunology 6,331-337.
    • (2005) Nature Immunology , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 25
    • 0033596123 scopus 로고    scopus 로고
    • Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: Transgenics and knockouts
    • Gerondakis, S., Grossmann, M., Nakamura, Y., Pohl, T., and Grumont, R.1999) Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene 18, 6888-6895.
    • (1999) Oncogene , vol.18 , pp. 6888-6895
    • Gerondakis, S.1    Grossmann, M.2    Nakamura, Y.3    Pohl, T.4    Grumont, R.5
  • 26
    • 33750467991 scopus 로고    scopus 로고
    • Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
    • Gerondakis, S., Grumont, R., Gugasyan, R., Wong, L., Isomura, I., Ho, W., and Banerjee, A.2006) Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene 25, 6781-6799.
    • (2006) Oncogene , vol.25 , pp. 6781-6799
    • Gerondakis, S.1    Grumont, R.2    Gugasyan, R.3    Wong, L.4    Isomura, I.5    Ho, W.6    Banerjee, A.7
  • 27
    • 0031833431 scopus 로고    scopus 로고
    • The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation
    • Gerondakis, S., Grumont, R., Rourke, I., and Grossmann, M.1998) The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation. Curr Opin Immunol 10, 353-359.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 353-359
    • Gerondakis, S.1    Grumont, R.2    Rourke, I.3    Grossmann, M.4
  • 29
    • 0026043866 scopus 로고
    • Fatal lymphoreticular disease in the scurfy sf mouse requires T cells that mature in a sf thymic environment: Potential model for thymic education
    • U S A
    • Godfrey, V. L., Wilkinson, J. E., Rinchik, E. M., and Russell, L. B.1991) Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education. Proc Natl Acad Sci U S A 88, 5528-5532.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 5528-5532
    • Godfrey, V.L.1    Wilkinson, J.E.2    Rinchik, E.M.3    Russell, L.B.4
  • 31
    • 0025179104 scopus 로고
    • The murine c-rel proto-oncogene encodes two mRNAs the expression of which is modulated by lymphoid stimuli
    • Grumont, R. J., and Gerondakis, S.1990a) The murine c-rel proto-oncogene encodes two mRNAs the expression of which is modulated by lymphoid stimuli. Oncogene Research 5, 245-254.
    • (1990) Oncogene Research , vol.5 , pp. 245-254
    • Grumont, R.J.1    Gerondakis, S.2
  • 32
    • 0025475425 scopus 로고
    • Murine c-rel transcription is rapidly induced in Tcells and fibroblasts by mitogenic agents and the phorbol ester 12-O-tetradecanoylphorbol-13- acetate
    • Grumont, R. J., and Gerondakis, S.1990b) Murine c-rel transcription is rapidly induced in Tcells and fibroblasts by mitogenic agents and the phorbol ester 12-O-tetradecanoylphorbol-13- acetate. Cell Growth & Differentiation 1, 345-350.
    • (1990) Cell Growth & Differentiation , vol.1 , pp. 345-350
    • Grumont, R.J.1    Gerondakis, S.2
  • 34
    • 0032449326 scopus 로고    scopus 로고
    • The avian transcription factor c-Rel is expressed in lymphocyte precursor cells and antigenpresenting cells during thymus development
    • Huguet, C., Bouali, F., Enrietto, P. J., Stehelin, D., Vandenbunder, B., and Abbadie, C.1998) The avian transcription factor c-Rel is expressed in lymphocyte precursor cells and antigenpresenting cells during thymus development. Developmental Immunology 5, 247-261.
    • (1998) Developmental Immunology , vol.5 , pp. 247-261
    • Huguet, C.1    Bouali, F.2    Enrietto, P.J.3    Stehelin, D.4    Vandenbunder, B.5    Abbadie, C.6
  • 36
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov, II, McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J., and Littman, D. R.2006) The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126, 1121-1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 40
    • 33746098905 scopus 로고    scopus 로고
    • + regulatory T cells in the hematolymphoid system
    • + regulatory T cells in the hematolymphoid system. Experimental Hematology 34, 1033-1040.
    • (2006) Experimental Hematology , vol.34 , pp. 1033-1040
    • Kim, C.H.1
  • 41
    • 33746379546 scopus 로고    scopus 로고
    • The role of the transcription factor Foxp3 in the development of regulatory T cells
    • Kim, J. M., and Rudensky, A.2006) The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunological Reviews 212, 86-98.
    • (2006) Immunological Reviews , vol.212 , pp. 86-98
    • Kim, J.M.1    Rudensky, A.2
  • 42
    • 33746351318 scopus 로고    scopus 로고
    • Making regulatory T cells with defined antigen specificity: Role in autoimmunity and cancer
    • Kretschmer, K., Apostolou, I., Jaeckel, E., Khazaie, K., and von Boehmer, H.2006) Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer. Immunological Reviews 212, 163-169.
    • (2006) Immunological Reviews , vol.212 , pp. 163-169
    • Kretschmer, K.1    Apostolou, I.2    Jaeckel, E.3    Khazaie, K.4    Von Boehmer, H.5
  • 43
    • 0037317269 scopus 로고    scopus 로고
    • Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells
    • Kutlu, B., Darville, M. I., Cardozo, A. K., and Eizirik, D. L.2003) Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells. Diabetes 52, 348-355.
    • (2003) Diabetes , vol.52 , pp. 348-355
    • Kutlu, B.1    Darville, M.I.2    Cardozo, A.K.3    Eizirik, D.L.4
  • 44
    • 0028973284 scopus 로고
    • Interleukin-1 betainduced nitric oxide synthase expression by rat pancreatic beta-cells: Evidence for the involvement of nuclear factor kappa B in the signaling mechanism
    • Kwon, G., Corbett, J. A., Rodi, C. P., Sullivan, P., and McDaniel, M. L.1995) Interleukin-1 betainduced nitric oxide synthase expression by rat pancreatic beta-cells: evidence for the involvement of nuclear factor kappa B in the signaling mechanism. Endocrinology 136, 4790-4795.
    • (1995) Endocrinology , vol.136 , pp. 4790-4795
    • Kwon, G.1    Corbett, J.A.2    Rodi, C.P.3    Sullivan, P.4    McDaniel, M.L.5
  • 48
    • 33748448717 scopus 로고    scopus 로고
    • Transforming growth factor-beta controls development homeostasis and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms
    • Li, M. O., Sanjabi, S., and Flavell, R. A.2006) Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity 25, 455-471.
    • (2006) Immunity , vol.25 , pp. 455-471
    • Li, M.O.1    Sanjabi, S.2    Flavell, R.A.3
  • 50
    • 0033023431 scopus 로고    scopus 로고
    • C-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function
    • Liou, H. C., Jin, Z., Tumang, J., Andjelic, S., Smith, K. A., and Liou, M. L.1999) c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. International Immunology 11, 361-371.
    • (1999) International Immunology , vol.11 , pp. 361-371
    • Liou, H.C.1    Jin, Z.2    Tumang, J.3    Andjelic, S.4    Smith, K.A.5    Liou, M.L.6
  • 53
    • 71749088574 scopus 로고    scopus 로고
    • Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
    • Long, M., Park, S. G., Strickland, I., Hayden, M. S., and Ghosh, S.2009) Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity 31, 921-931.
    • (2009) Immunity , vol.31 , pp. 921-931
    • Long, M.1    Park, S.G.2    Strickland, I.3    Hayden, M.S.4    Ghosh, S.5
  • 56
    • 18244379306 scopus 로고    scopus 로고
    • Interactions of NF-kappaB with chromatin: The art of being at the right place at the right time
    • Natoli, G., Saccani, S., Bosisio, D., and Marazzi, I.2005) Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time. Nature Immunology 6, 439-445.
    • (2005) Nature Immunology , vol.6 , pp. 439-445
    • Natoli, G.1    Saccani, S.2    Bosisio, D.3    Marazzi, I.4
  • 57
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra, A., and Vieira, P.2004) Regulatory T cells and mechanisms of immune system control. Nat Med 10, 801-805.
    • (2004) Nat. Med. , vol.10 , pp. 801-805
    • O'Garra, A.1    Vieira, P.2
  • 58
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H. L.1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 59
    • 0141562049 scopus 로고    scopus 로고
    • Nuclear factor-kappaB translocation mediates double-stranded ribonucleic acid-induced NIT-1 beta-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor receptor-associated ligand TRAIL
    • Robbins, M. A., Maksumova, L., Pocock, E., and Chantler, J. K.2003) Nuclear factor-kappaB translocation mediates double-stranded ribonucleic acid-induced NIT-1 beta-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor receptor-associated ligand (TRAIL). Endocrinology 144, 4616-4625.
    • (2003) Endocrinology , vol.144 , pp. 4616-4625
    • Robbins, M.A.1    Maksumova, L.2    Pocock, E.3    Chantler, J.K.4
  • 60
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnani, S.1997) The Th1/Th2 paradigm. Immunology Today 18, 263-266.
    • (1997) Immunology Today , vol.18 , pp. 263-266
    • Romagnani, S.1
  • 62
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nature Immunology 6, 345-352.
    • (2005) Nature Immunology , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 64
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses
    • Sha, W. C., Liou, H. C., Tuomanen, E. I., and Baltimore, D.1995) Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell 80, 321-330.
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou, H.C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 65
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: Multiple varieties of T regulatory cells
    • Shevach, E. M.2006) From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25, 195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 68
    • 0023890077 scopus 로고
    • Detection and characterization of the protein encoded by the chicken c-rel protooncogene
    • Simek, S., and Rice, N. R.1988) Detection and characterization of the protein encoded by the chicken c-rel protooncogene. Oncogene Research 2, 103-119.
    • (1988) Oncogene Research , vol.2 , pp. 103-119
    • Simek, S.1    Rice, N.R.2
  • 69
    • 0033053791 scopus 로고    scopus 로고
    • The transcriptional regulator Rel is essential for antigen receptor-mediated stimulation of mature T cells but dispensable for positive and negative selection of thymocytes and T cell apoptosis
    • Strasser, A., Grumont, R. J., Stanley, M. L., and Gerondakis, S.1999) The transcriptional regulator Rel is essential for antigen receptor-mediated stimulation of mature T cells but dispensable for positive and negative selection of thymocytes and T cell apoptosis. European Journal of Immunology 29, 928-935.
    • (1999) European Journal of Immunology , vol.29 , pp. 928-935
    • Strasser, A.1    Grumont, R.J.2    Stanley, M.L.3    Gerondakis, S.4
  • 70
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin IL-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • Sutton, C., Brereton, C., Keogh, B., Mills, K. H., and Lavelle, E. C.2006) A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. Journal of Experimental Medicine 203, 1685-1691.
    • (2006) Journal of Experimental Medicine , vol.203 , pp. 1685-1691
    • Sutton, C.1    Brereton, C.2    Keogh, B.3    Mills, K.H.4    Lavelle, E.C.5
  • 72
    • 0032528433 scopus 로고    scopus 로고
    • Respiratory syncytial virusinduced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha
    • Thomas, L. H., Friedland, J. S., Sharland, M., and Becker, S.1998) Respiratory syncytial virusinduced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha. Journal of Immunology 161, 1007-1016.
    • (1998) Journal of Immunology , vol.161 , pp. 1007-1016
    • Thomas, L.H.1    Friedland, J.S.2    Sharland, M.3    Becker, S.4
  • 75
    • 33745818935 scopus 로고    scopus 로고
    • TGFbeta1 a Jack of all trades: The link with proinflammatory IL-17-producing T cells
    • Veldhoen, M., and Stockinger, B.2006) TGFbeta1, a "Jack of all trades": the link with proinflammatory IL-17-producing T cells. Trends in Immunology 27, 358-361.
    • (2006) Trends in Immunology , vol.27 , pp. 358-361
    • Veldhoen, M.1    Stockinger, B.2
  • 77
    • 0032727865 scopus 로고    scopus 로고
    • Activation of AP-1 and nuclear factorkappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes
    • Vollgraf, U., Wegner, M., and Richter-Landsberg, C.1999) Activation of AP-1 and nuclear factorkappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes. Journal of Neurochemistry 73, 2501-2509.
    • (1999) Journal of Neurochemistry , vol.73 , pp. 2501-2509
    • Vollgraf, U.1    Wegner, M.2    Richter-Landsberg, C.3
  • 78
    • 0030907779 scopus 로고    scopus 로고
    • C-Rel is a target of pentoxifylline- mediated inhibition of T lymphocyte activation
    • Wang, W., Tam, W. F., Hughes, C. C., Rath, S., and Sen, R.1997) c-Rel is a target of pentoxifylline- mediated inhibition of T lymphocyte activation. Immunity 6, 165-174.
    • (1997) Immunity , vol.6 , pp. 165-174
    • Wang, W.1    Tam, W.F.2    Hughes, C.C.3    Rath, S.4    Sen, R.5
  • 80
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB a member of the NF-kappa B/Rel family
    • Weih, F., Carrasco, D., Durham, S. K., Barton, D. S., Rizzo, C. A., Ryseck, R. P., Lira, S. A., and Bravo, R.1995) Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell 80, 331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8
  • 85
    • 0032575379 scopus 로고    scopus 로고
    • Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: Discrimination between free and NF-kappaB-bound substrate
    • Zandi, E., Chen, Y., and Karin, M.1998) Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science 281, 1360-1363.
    • (1998) Science , vol.281 , pp. 1360-1363
    • Zandi, E.1    Chen, Y.2    Karin, M.3
  • 86
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex IKK contains two kinase subunits IKKalpha and IKKbeta necessary for IkappaB phosphorylation and NF-kappaB activation
    • Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., and Karin, M.1997) The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91, 243-252.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 87
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng, Y., Josefowicz, S., Chaudhry, A., Peng, X. P., Forbush, K., and Rudensky, A. Y.2010) Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 463, 808-812.
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6


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