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Volumn 187, Issue 9, 2011, Pages 4483-4491

The NF-κB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; RETINOID RELATED ORPHAN RECEPTOR GAMMA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR REL;

EID: 80555133361     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101757     Document Type: Article
Times cited : (69)

References (46)
  • 1
    • 0022640843 scopus 로고    scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136: 2348-2357.
    • J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 2
    • 27544490377 scopus 로고    scopus 로고
    • + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • DOI 10.1038/ni1254, PII N1254
    • Harrington, L. E., R. D. Hatton, P. R. Mangan, H. Turner, T. L. Murphy, K. M. Murphy, and C. T. Weaver. 2005. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6: 1123-1132. (Pubitemid 41541790)
    • (2005) Nature Immunology , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 9
    • 33748588423 scopus 로고    scopus 로고
    • + T Helper Cells
    • DOI 10.1016/j.cell.2006.07.035, PII S0092867406011056
    • Ivanov, I. I., B. S. McKenzie, L. Zhou, C. E. Tadokoro, A. Lepelley, J. J. Lafaille, D. J. Cua, and D. R. Littman. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133. (Pubitemid 44380299)
    • (2006) Cell , vol.126 , Issue.6 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 10
    • 35549010987 scopus 로고    scopus 로고
    • The origin and application of experimental autoimmune encephalomyelitis
    • DOI 10.1038/nri2190, PII NRI2190
    • Baxter, A. G. 2007. The origin and application of experimental autoimmune encephalomyelitis. Nat. Rev. Immunol. 7: 904-912. (Pubitemid 350006239)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.11 , pp. 904-912
    • Baxter, A.G.1
  • 12
    • 0036677420 scopus 로고    scopus 로고
    • Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
    • DOI 10.1172/JCI200215751
    • Becher, B., B. G. Durell, and R. J. Noelle. 2002. Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. J. Clin. Invest. 110: 493-497. (Pubitemid 34919703)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.4 , pp. 493-497
    • Becher, B.1    Durell, B.G.2    Noelle, R.J.3
  • 16
    • 23844478869 scopus 로고    scopus 로고
    • + regulatory cells within the central nervous system
    • McGeachy, M. J., L. A. Stephens, and S. M. Anderton. 2005. Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J. Immunol. 175: 3025-3032. (Pubitemid 41170521)
    • (2005) Journal of Immunology , vol.175 , Issue.5 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 18
    • 0348223787 scopus 로고    scopus 로고
    • + Regulatory T Cells by TGF-beta Induction of Transcription Factor Foxp3
    • DOI 10.1084/jem.20030152
    • Chen, W., W. Jin, N. Hardegen, K. J. Lei, L. Li, N. Marinos, G. McGrady, and S. M. Wahl. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4 +CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886. (Pubitemid 38032120)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.12 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.-J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 19
    • 33750467991 scopus 로고    scopus 로고
    • Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
    • DOI 10.1038/sj.onc.1209944, PII 1209944
    • Gerondakis, S., R. Grumont, R. Gugasyan, L. Wong, I. Isomura, W. Ho, and A. Banerjee. 2006. Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene 25: 6781-6799. (Pubitemid 44657852)
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6781-6799
    • Gerondakis, S.1    Grumont, R.2    Gugasyan, R.3    Wong, L.4    Isomura, I.5    Ho, W.6    Banerjee, A.7
  • 21
    • 0043092575 scopus 로고    scopus 로고
    • Distinctions between c-Rel and other NFkappaB proteins in immunity and disease
    • Liou, H. C., and C. Y. Hsia. 2003. Distinctions between c-Rel and other NFkappaB proteins in immunity and disease. Bioessays 25: 767-780.
    • (2003) Bioessays , vol.25 , pp. 767-780
    • Liou, H.C.1    Hsia, C.Y.2
  • 22
    • 73949090725 scopus 로고    scopus 로고
    • C-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
    • Published erratum appears in 2010. J. Exp. Med. 207: 899
    • Isomura, I., S. Palmer, R. J. Grumont, K. Bunting, G. Hoyne, N. Wilkinson, A. Banerjee, A. Proietto, R. Gugasyan, L. Wu, et al. 2009. c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells. [Published erratum appears in 2010. J. Exp. Med. 207: 899.] J. Exp. Med. 206: 3001-3014.
    • (2009) J. Exp. Med. , vol.206 , pp. 3001-3014
    • Isomura, I.1    Palmer, S.2    Grumont, R.J.3    Bunting, K.4    Hoyne, G.5    Wilkinson, N.6    Banerjee, A.7    Proietto, A.8    Gugasyan, R.9    Wu, L.10
  • 23
    • 77956944349 scopus 로고    scopus 로고
    • Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel
    • Chen, G., K. Hardy, K. Bunting, S. Daley, L. Ma, and M. F. Shannon. 2010. Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel. J. Immunol. 185: 2350-2359.
    • (2010) J. Immunol. , vol.185 , pp. 2350-2359
    • Chen, G.1    Hardy, K.2    Bunting, K.3    Daley, S.4    Ma, L.5    Shannon, M.F.6
  • 25
    • 37649021448 scopus 로고    scopus 로고
    • Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester
    • DOI 10.1038/nprot.2007.296, PII NPROT.2007.296
    • Quah, B. J., H. S. Warren, and C. R. Parish. 2007. Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nat. Protoc. 2: 2049-2056. (Pubitemid 351565842)
    • (2007) Nature Protocols , vol.2 , Issue.9 , pp. 2049-2056
    • Quah, B.J.C.1    Warren, H.S.2    Parish, C.R.3
  • 26
    • 34249799899 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappaB transcription factor c-Rel
    • Bunting, K., S. Rao, K. Hardy, D. Woltring, G. S. Denyer, J. Wang, S. Gerondakis, and M. F. Shannon. 2007. Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c- Rel. J. Immunol. 178: 7097-7109. (Pubitemid 46847436)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 7097-7109
    • Bunting, K.1    Rao, S.2    Hardy, K.3    Woltring, D.4    Denyer, G.S.5    Wang, J.6    Gerondalds, S.7    Shannon, M.F.8
  • 27
    • 37649019847 scopus 로고    scopus 로고
    • Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data
    • DOI 10.1038/nprot.2007.297, PII NPROT.2007.297
    • Hawkins, E. D., M. Hommel, M. L. Turner, F. L. Battye, J. F. Markham, and P. D. Hodgkin. 2007. Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nat. Protoc. 2: 2057-2067. (Pubitemid 351565843)
    • (2007) Nature Protocols , vol.2 , Issue.9 , pp. 2057-2067
    • Hawkins, E.D.1    Hommel, M.2    Turner, M.L.3    Battye, F.L.4    Markham, J.F.5    Hodgkin, P.D.6
  • 28
    • 3242888285 scopus 로고    scopus 로고
    • rVISTA 2.0: Evolutionary analysis of transcription factor binding sites
    • Loots, G. G., and I. Ovcharenko. 2004. rVISTA 2.0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res. 32(Web Server issue): W217-W221.
    • (2004) Nucleic Acids Res. , vol.32 , Issue.WEB SERVER ISSUE
    • Loots, G.G.1    Ovcharenko, I.2
  • 29
    • 0033812835 scopus 로고    scopus 로고
    • Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication
    • Bert, A. G., J. Burrows, C. S. Osborne, and P. N. Cockerill. 2000. Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication. Plasmid 44: 173-182.
    • (2000) Plasmid , vol.44 , pp. 173-182
    • Bert, A.G.1    Burrows, J.2    Osborne, C.S.3    Cockerill, P.N.4
  • 30
    • 33845947424 scopus 로고    scopus 로고
    • Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells
    • Carmody, R. J., Q. Ruan, H. C. Liou, and Y. H. Chen. 2007. Essential roles of c- Rel in TLR-induced IL-23 p19 gene expression in dendritic cells. J. Immunol. 178: 186-191. (Pubitemid 46033600)
    • (2007) Journal of Immunology , vol.178 , Issue.1 , pp. 186-191
    • Carmody, R.J.1    Ruan, Q.2    Liou, H.-C.3    Chen, Y.H.4
  • 31
    • 0346195644 scopus 로고    scopus 로고
    • c-Rel is required for chromatin remodeling across the IL-2 gene promoter
    • Rao, S., S. Gerondakis, D. Woltring, and M. F. Shannon. 2003. c-Rel is required for chromatin remodeling across the IL-2 gene promoter. J. Immunol. 170: 3724-3731. (Pubitemid 36359242)
    • (2003) Journal of Immunology , vol.170 , Issue.7 , pp. 3724-3731
    • Rao, S.1    Gerondakis, S.2    Woltring, D.3    Shannon, M.F.4
  • 33
    • 0030294284 scopus 로고    scopus 로고
    • High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters
    • DOI 10.1016/S1074-7613(00)80503-8
    • Himes, S. R., L. S. Coles, R. Reeves, and M. F. Shannon. 1996. High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters. Immunity 5: 479-489. (Pubitemid 26423475)
    • (1996) Immunity , vol.5 , Issue.5 , pp. 479-489
    • Himes, S.R.1    Coles, L.S.2    Reeves, R.3    Shannon, M.F.4
  • 35
    • 46749156754 scopus 로고    scopus 로고
    • Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis
    • Coquet, J. M., S. Chakravarti, M. J. Smyth, and D. I. Godfrey. 2008. Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis. J. Immunol. 180: 7097-7101.
    • (2008) J. Immunol. , vol.180 , pp. 7097-7101
    • Coquet, J.M.1    Chakravarti, S.2    Smyth, M.J.3    Godfrey, D.I.4
  • 36
    • 46749133961 scopus 로고    scopus 로고
    • IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo
    • Sonderegger, I., J. Kisielow, R. Meier, C. King, and M. Kopf. 2008. IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo. Eur. J. Immunol. 38: 1833-1838.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1833-1838
    • Sonderegger, I.1    Kisielow, J.2    Meier, R.3    King, C.4    Kopf, M.5
  • 41
    • 0032217092 scopus 로고    scopus 로고
    • RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells
    • He, Y. W., M. L. Deftos, E. W. Ojala, and M. J. Bevan. 1998. RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity 9: 797-806.
    • (1998) Immunity , vol.9 , pp. 797-806
    • He, Y.W.1    Deftos, M.L.2    Ojala, E.W.3    Bevan, M.J.4
  • 46
    • 79551684235 scopus 로고    scopus 로고
    • Increased Th17 rather than Th1 alloimmune response is associated with cardiac allograft vasculopathy after hypothermic preservation in the rat
    • Syrjälä, S. O., M. A. Keränen, R. Tuuminen, A. I. Nykänen, M. Tammi, R. Krebs, and K. B. Lemström. 2010. Increased Th17 rather than Th1 alloimmune response is associated with cardiac allograft vasculopathy after hypothermic preservation in the rat. J. Heart Lung Transplant. 29: 1047-1057.
    • (2010) J. Heart Lung Transplant. , vol.29 , pp. 1047-1057
    • Syrjälä, S.O.1    Keränen, M.A.2    Tuuminen, R.3    Nykänen, A.I.4    Tammi, M.5    Krebs, R.6    Lemström, K.B.7


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