Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation

Cell Reports

Volumn 9, Issue 4, 2014, Pages 1292-1305

  Gewies, Andreas ^a,b   Gorka, Oliver ^a   Bergmann, Hanna ^a   Pechloff, Konstanze ^a,b   Petermann, Franziska ^a   Jeltsch, Katharina M ^c,f   Rudelius, Martina ^d   Kriegsmann, Mark ^e   Weichert, Wilko ^e   Horsch, Marion ^f   Beckers, Johannes ^f,g   Wurst, Wolfgang ^f,g,h,i   Heikenwalder, Mathias ^g   Korn, Thomas ^a,h   Heissmeyer, Vigo ^c,f   Ruland, Jürgen ^a,b,j  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^h Technische Universität München Munich Cluster for Systems Neurology   (Germany)

ⁱ GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^j German Center for Infection Research   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; GAMMA INTERFERON; I KAPPA B; MESSENGER RNA; PARACASPASE; PROTEIN MALT1; PROTEINASE; REGNASE 1; REGULATOR PROTEIN; ROQUIN 1; ROQUIN 2; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; MALT1 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; AUTOINFLAMMATORY DISEASE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INACTIVATION; FEMALE; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN CLEAVAGE; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; MUCOSAL IMMUNITY; MUTANT MOUSE STRAIN; PATHOLOGY;

ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; CASPASES; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; IMMUNITY, MUCOSAL; INFLAMMATION; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE, MUTANT STRAINS; NEOPLASM PROTEINS; NERVE DEGENERATION; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 84912110913     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.10.044     Document Type: Article

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