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Volumn 7, Issue 329, 2014, Pages

T cell receptor-dependent activation of mTOR signaling in T Cells Is Mediated by Carma1 and MALT1, but not Bcl10

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CASPASE; CASPASE RECRUITMENT DOMAIN CONTAINING MEMBRANE ASSOCIATED PROTEIN 1; CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA PROTEIN 1; PROTEIN BCL 10; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 84902651290     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004983     Document Type: Article
Times cited : (13)

References (66)
  • 2
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • M. Laplante, D. M. Sabatini, mTOR signaling in growth control and disease. Cell 149, 274-293 (2012).
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 3
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • S. Wullschleger, R. Loewith, M. N. Hall, TOR signaling in growth and metabolism. Cell 124, 471-484 (2006).
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 4
    • 33745150462 scopus 로고    scopus 로고
    • Ribosomal protein S6 phosphorylation: From protein synthesis to cell size
    • I. Ruvinsky, O. Meyuhas, Ribosomal protein S6 phosphorylation: From protein synthesis to cell size. Trends Biochem. Sci. 31, 342-348 (2006).
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 342-348
    • Ruvinsky, I.1    Meyuhas, O.2
  • 5
    • 84860305782 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinases and leukocyte migration
    • S. G. Ward, Phosphoinositide 3-kinases and leukocyte migration. Curr. Immunol. Rev. 8, 154-160 (2013).
    • (2013) Curr. Immunol. Rev. , vol.8 , pp. 154-160
    • Ward, S.G.1
  • 7
    • 29144438951 scopus 로고    scopus 로고
    • Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response
    • S. Sulic, L. Panic, M. Barkic, M. Mercep, M. Uzelac, S. Volarevic, Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response. Genes Dev. 19, 3070-3082 (2005).
    • (2005) Genes Dev , vol.19 , pp. 3070-3082
    • Sulic, S.1    Panic, L.2    Barkic, M.3    Mercep, M.4    Uzelac, M.5    Volarevic, S.6
  • 8
    • 0037716820 scopus 로고    scopus 로고
    • Regulation and function of serine kinase networks in lymphocytes
    • D. A. Cantrell, Regulation and function of serine kinase networks in lymphocytes. Curr. Opin. Immunol. 15, 294-298 (2003).
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 294-298
    • Cantrell, D.A.1
  • 9
    • 40149099723 scopus 로고    scopus 로고
    • Critical roles of the PI3K/Akt signaling pathway in T cell development
    • M. M. Juntilla, G. A. Koretzky, Critical roles of the PI3K/Akt signaling pathway in T cell development. Immunol. Lett. 116, 104-110 (2008).
    • (2008) Immunol. Lett. , vol.116 , pp. 104-110
    • Juntilla, M.M.1    Koretzky, G.A.2
  • 10
    • 0038578823 scopus 로고    scopus 로고
    • The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3
    • L. P. Kane, A. Weiss, The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3. Immunol. Rev. 192, 7-20 (2003).
    • (2003) Immunol. Rev. , vol.192 , pp. 7-20
    • Kane, L.P.1    Weiss, A.2
  • 12
    • 33846235557 scopus 로고    scopus 로고
    • The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptorsignaling pathway
    • M. Blonska, B. P. Pappu, R. Matsumoto, H. Li, B. Su, D. Wang, X. Lin, The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptorsignaling pathway. Immunity 26, 55-66 (2007).
    • (2007) Immunity , vol.26 , pp. 55-66
    • Blonska, M.1    Pappu, B.P.2    Matsumoto, R.3    Li, H.4    Su, B.5    Wang, D.6    Lin, X.7
  • 13
    • 1942469524 scopus 로고    scopus 로고
    • MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kB activation
    • T. Che, Y. You, D. Wang, M. J. Tanner, V. M. Dixit, X. Lin, MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kB activation. J. Biol. Chem. 279, 15870-15876 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 15870-15876
    • Che, T.1    You, Y.2    Wang, D.3    Tanner, M.J.4    Dixit, V.M.5    Lin, X.6
  • 19
    • 0036884169 scopus 로고    scopus 로고
    • Lymphoid malignancies: The dark side of B-cell differentiation
    • A. L. Shaffer, A. Rosenwald, L. M. Staudt, Lymphoid malignancies: The dark side of B-cell differentiation. Nat. Rev. Immunol. 2, 920-932 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 920-932
    • Shaffer, A.L.1    Rosenwald, A.2    Staudt, L.M.3
  • 22
    • 78650883911 scopus 로고    scopus 로고
    • Regulation of NF-κB signaling by caspases and MALT1 paracaspase
    • J. Staal, T. Bekaert, R. Beyaert, Regulation of NF-κB signaling by caspases and MALT1 paracaspase. Cell Res. 21, 40-54 (2011).
    • (2011) Cell Res , vol.21 , pp. 40-54
    • Staal, J.1    Bekaert, T.2    Beyaert, R.3
  • 23
    • 33748752151 scopus 로고    scopus 로고
    • The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
    • S. M. Schieke, D. Phillips, J. P. McCoy, A. M. Aponte, R. F. Shen, R. S. Balaban, T. Finkel, The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J. Biol. Chem. 281, 27643-27652 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 27643-27652
    • Schieke, S.M.1    Phillips, D.2    McCoy, J.P.3    Aponte, A.M.4    Shen, R.F.5    Balaban, R.S.6    Finkel, T.7
  • 24
    • 84874226167 scopus 로고    scopus 로고
    • mTOR and metabolic pathways in T cell quiescence and functional activation
    • K. Yang, H. Chi, mTOR and metabolic pathways in T cell quiescence and functional activation. Semin. Immunol. 24, 421-428 (2012).
    • (2012) Semin. Immunol. , vol.24 , pp. 421-428
    • Yang, K.1    Chi, H.2
  • 25
    • 33644772836 scopus 로고    scopus 로고
    • CARMA1 is required for Akt-mediated NF-κB activation in T cells
    • P. Narayan, B. Holt, R. Tosti, L. Kane, CARMA1 is required for Akt-mediated NF-κB activation in T cells. Mol. Cell. Biol. 26, 2327-2336 (2006).
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2327-2336
    • Narayan, P.1    Holt, B.2    Tosti, R.3    Kane, L.4
  • 28
    • 70350418625 scopus 로고    scopus 로고
    • mTORsignaling at a glance
    • M. Laplante, D. M. Sabatini,mTORsignaling at a glance. J. Cell Sci. 122, 3589-3594 (2009).
    • (2009) J. Cell Sci. , vol.122 , pp. 3589-3594
    • Laplante, M.1    Sabatini, D.M.2
  • 29
    • 79953211540 scopus 로고    scopus 로고
    • Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling
    • I. Tato, R. Bartrons, F. Ventura, J. L. Rosa, Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling. J. Biol. Chem. 286, 6128-6142 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 6128-6142
    • Tato, I.1    Bartrons, R.2    Ventura, F.3    Rosa, J.L.4
  • 30
    • 0024328679 scopus 로고
    • Mechanisms of T cell activation by the calcium ionophore ionomycin
    • T. Chatila, L. Silverman, R. Miller, R. Geha, Mechanisms of T cell activation by the calcium ionophore ionomycin. J. Immunol. 143, 1283-1289 (1989).
    • (1989) J. Immunol. , vol.143 , pp. 1283-1289
    • Chatila, T.1    Silverman, L.2    Miller, R.3    Geha, R.4
  • 32
    • 77957054466 scopus 로고    scopus 로고
    • The mammalian target of rapamycin: Linking T cell differentiation, function, and metabolism
    • J. D. Powell, G. M. Delgoffe, The mammalian target of rapamycin: Linking T cell differentiation, function, and metabolism. Immunity 33, 301-311 (2010).
    • (2010) Immunity , vol.33 , pp. 301-311
    • Powell, J.D.1    Delgoffe, G.M.2
  • 33
    • 34249284512 scopus 로고    scopus 로고
    • mTOR at the crossroads of T cell proliferation and tolerance
    • A. Mondino, D. L. Mueller, mTOR at the crossroads of T cell proliferation and tolerance. Semin. Immunol. 19, 162-172 (2007).
    • (2007) Semin. Immunol. , vol.19 , pp. 162-172
    • Mondino, A.1    Mueller, D.L.2
  • 34
    • 33747819801 scopus 로고    scopus 로고
    • mTOR and cancer: Insights into a complex relationship
    • D. M. Sabatini, mTOR and cancer: Insights into a complex relationship. Nat. Rev. Cancer 6, 729-734 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 729-734
    • Sabatini, D.M.1
  • 35
    • 34249694900 scopus 로고    scopus 로고
    • Post-translational modifications regulate distinct functions of CARMA1 and BCL10
    • M. Thome, R. Weil, Post-translational modifications regulate distinct functions of CARMA1 and BCL10. Trends Immunol. 28, 281-288 (2007).
    • (2007) Trends Immunol , vol.28 , pp. 281-288
    • Thome, M.1    Weil, R.2
  • 37
    • 2442612540 scopus 로고    scopus 로고
    • CARMA1, BCL-10 and MALT1 in lymphocyte development and activation
    • M. Thome, CARMA1, BCL-10 and MALT1 in lymphocyte development and activation. Nat. Rev. Immunol. 4, 348-359 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 348-359
    • Thome, M.1
  • 39
    • 42949098959 scopus 로고    scopus 로고
    • NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kB activation
    • C. J. Wu, J. D. Ashwell, NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kB activation. Proc. Natl. Acad. Sci. U.S.A. 105, 3023-3028 (2008).
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3023-3028
    • Wu, C.J.1    Ashwell, J.D.2
  • 41
    • 2342629277 scopus 로고    scopus 로고
    • The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
    • L. Sun, L. Deng, C. K. Ea, Z. P. Xia, Z. J. Chen, The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol. Cell 14, 289-301 (2004).
    • (2004) Mol. Cell , vol.14 , pp. 289-301
    • Sun, L.1    Deng, L.2    Ea, C.K.3    Xia, Z.P.4    Chen, Z.J.5
  • 42
    • 0023219739 scopus 로고
    • Interleukin 2 and diacylglycerol stimulate phosphorylation of 40 S ribosomal S6 protein. Correlation with increased protein synthesis and S6 kinase activation
    • S. W. Evans, W. L. Farrar, Interleukin 2 and diacylglycerol stimulate phosphorylation of 40 S ribosomal S6 protein. Correlation with increased protein synthesis and S6 kinase activation. J. Biol. Chem. 262, 4624-4630 (1987).
    • (1987) J. Biol. Chem. , vol.262 , pp. 4624-4630
    • Evans, S.W.1    Farrar, W.L.2
  • 43
    • 77953534607 scopus 로고    scopus 로고
    • Metabolism in T cell activation and differentiation
    • E. L. Pearce, Metabolism in T cell activation and differentiation. Curr. Opin. Immunol. 22, 314-320 (2010).
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 314-320
    • Pearce, E.L.1
  • 44
    • 0033635249 scopus 로고    scopus 로고
    • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability
    • J. C. Rathmell, M. G. V. Heiden, M. H. Harris, K. A. Frauwirth, C. B. Thompson, In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol. Cell 6, 683-692 (2000).
    • (2000) Mol. Cell , vol.6 , pp. 683-692
    • Rathmell, J.C.1    Heiden, M.G.V.2    Harris, M.H.3    Frauwirth, K.A.4    Thompson, C.B.5
  • 45
    • 0036320205 scopus 로고    scopus 로고
    • Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
    • A. L. Edinger, C. B. Thompson, Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell 13, 2276-2288 (2002).
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2276-2288
    • Edinger, A.L.1    Thompson, C.B.2
  • 46
    • 78649955075 scopus 로고    scopus 로고
    • The dynamic distribution of CARD11 at the immunological synapse is regulated by the inhibitory kinesin GAKIN
    • R. L. Lamason, A. Kupfer, J. L. Pomerantz, The dynamic distribution of CARD11 at the immunological synapse is regulated by the inhibitory kinesin GAKIN. Mol. Cell 40, 798-809 (2010).
    • (2010) Mol. Cell , vol.40 , pp. 798-809
    • Lamason, R.L.1    Kupfer, A.2    Pomerantz, J.L.3
  • 48
    • 0030905166 scopus 로고    scopus 로고
    • Target of rapamycin proteins and their kinase activities are required for meiosis
    • X. F. Zheng, S. L. Schreiber, Target of rapamycin proteins and their kinase activities are required for meiosis. Proc. Natl. Acad. Sci. U.S.A. 94, 3070-3075 (1997).
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 3070-3075
    • Zheng, X.F.1    Schreiber, S.L.2
  • 50
    • 48349125069 scopus 로고    scopus 로고
    • The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
    • H. Kawadler, M. A. Gantz, J. L. Riley, X. Yang, The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol. Cell 31, 415-421 (2008).
    • (2008) Mol. Cell , vol.31 , pp. 415-421
    • Kawadler, H.1    Gantz, M.A.2    Riley, J.L.3    Yang, X.4
  • 51
    • 38449096218 scopus 로고    scopus 로고
    • A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2
    • A. F. Arechiga, B. D. Bell, S. Leverrier, B. M.Weist, M. Porter, Z. Wu, Y. Kanno, S. J. Ramos, S. T. Ong, R. Siegel, C. M. Walsh, A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J. Immunol. 179, 5291-5300 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 5291-5300
    • Arechiga, A.F.1    Bell, B.D.2    Leverrier, S.3    Weist, B.M.4    Porter, M.5    Wu, Z.6    Kanno, Y.7    Ramos, S.J.8    Ong, S.T.9    Siegel, R.10    Walsh, C.M.11
  • 54
    • 0142084679 scopus 로고    scopus 로고
    • Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation
    • J. Faridi, J. Fawcett, L. Wang, R. A. Roth, Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation. Am. J. Physiol. Endocrinol. Metab. 285, E964-E972 (2003).
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Faridi, J.1    Fawcett, J.2    Wang, L.3    Roth, R.A.4
  • 55
    • 0037097863 scopus 로고    scopus 로고
    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • D. C. Fingar, S. Salama, C. Tsou, E. Harlow, J. Blenis, Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16, 1472-1487 (2002).
    • (2002) Genes Dev , vol.16 , pp. 1472-1487
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3    Harlow, E.4    Blenis, J.5
  • 56
    • 77649213114 scopus 로고    scopus 로고
    • Tissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin's lymphoma
    • J. De, R. Brown, Tissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin's lymphoma. Int. J. Clin. Exp. Med. 3, 55-68 (2010).
    • (2010) Int. J. Clin. Exp. Med. , vol.3 , pp. 55-68
    • De, J.1    Brown, R.2
  • 57
    • 77954605430 scopus 로고    scopus 로고
    • Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: Therapeutic implications
    • L. V. Pham, A. T. Tamayo, C. Li, W. Bornmann, W. Priebe, R. J. Ford, Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: Therapeutic implications. Mol. Cancer Ther. 9, 2026-2036 (2010).
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 2026-2036
    • Pham, L.V.1    Tamayo, A.T.2    Li, C.3    Bornmann, W.4    Priebe, W.5    Ford, R.J.6
  • 60
    • 84860237060 scopus 로고    scopus 로고
    • Regulation and function of mTOR signalling in T cell fate decisions
    • H. Chi, Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 12, 325-338 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 325-338
    • Chi, H.1
  • 61
    • 84861157343 scopus 로고    scopus 로고
    • Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells
    • A. T. Waickman, J. D. Powell, Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells. J. Immunol. 188, 4721-4729 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 4721-4729
    • Waickman, A.T.1    Powell, J.D.2
  • 62
    • 84879195658 scopus 로고    scopus 로고
    • mTOR and lymphocyte metabolism
    • H. Zeng, H. Chi, mTOR and lymphocyte metabolism. Curr. Opin. Immunol. 25, 347-355 (2013).
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 347-355
    • Zeng, H.1    Chi, H.2
  • 63
    • 80053909808 scopus 로고    scopus 로고
    • Akt fine-tunes NF-κB-dependent gene expression during T cell activation
    • J. Cheng, B. Phong, D. C. Wilson, R. Hirsch, L. P. Kane, Akt fine-tunes NF-κB-dependent gene expression during T cell activation. J. Biol. Chem. 286, 36076-36085 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 36076-36085
    • Cheng, J.1    Phong, B.2    Wilson, D.C.3    Hirsch, R.4    Kane, L.P.5
  • 65
    • 33746047673 scopus 로고    scopus 로고
    • Complementinduced cell death by rituximab depends on CD20 expression level and acts complementary to antibody-dependent cellular cytotoxicity
    • T. van Meerten, R. S. van Rijn, S. Hol, A. Hagenbeek, S. B. Ebeling, Complementinduced cell death by rituximab depends on CD20 expression level and acts complementary to antibody-dependent cellular cytotoxicity. Clin. Cancer Res. 12, 4027-4035 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , pp. 4027-4035
    • Van Meerten, T.1    Van Rijn, R.S.2    Hol, S.3    Hagenbeek, A.4    Ebeling, S.B.5
  • 66
    • 84887446052 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation
    • M. E. Heid, P. A. Keyel, C. Kamga, S. Shiva, S. C. Watkins, R. D. Salter, Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J. Immunol. 191, 5230-5238 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 5230-5238
    • Heid, M.E.1    Keyel, P.A.2    Kamga, C.3    Shiva, S.4    Watkins, S.C.5    Salter, R.D.6


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