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Volumn 19, Issue 5, 2015, Pages 844-856

Epigenetic mechanisms in chronic obstructive pulmonary disease

Author keywords

Acetylation; COPD; DNA methylation; Epigenetics; Histone methylation; Phosphorylation; Ubiquitination

Indexed keywords

DNA; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE;

EID: 84942251911     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (36)

References (169)
  • 1
    • 58249099942 scopus 로고    scopus 로고
    • COPD as a disease of accelerated lung aging
    • ITO K, BARNES PJ. COPD as a disease of accelerated lung aging. Chest 2009;135:173-180.
    • (2009) Chest , vol.135 , pp. 173-180
    • Ito, K.1    Barnes, P.J.2
  • 2
    • 84866451788 scopus 로고    scopus 로고
    • Clinical factors affecting the direct cost of patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease
    • ORNEK T, TOR M, ALTIN R, ATALAR F, GEREDELI E, SOYLU O, ERBOY F. Clinical factors affecting the direct cost of patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease. Int J Med Sci 2012;9:285-290.
    • (2012) Int J Med Sci , vol.9 , pp. 285-290
    • Ornek, T.1    Tor, M.2    Altin, R.3    Atalar, F.4    Geredeli, E.5    Soylu, O.6    Erboy, F.7
  • 3
    • 84864604353 scopus 로고    scopus 로고
    • Suppressed expression of Tbox transcription factors is involved in senescence in chronic obstructive pulmonary disease
    • ACQUAAH-MENSAH GK, MALHOTRA D, VULIMIRI M, MCDERMOTT JE, BISWAL S. Suppressed expression of Tbox transcription factors is involved in senescence in chronic obstructive pulmonary disease. PLoS Comput Biol 2012;8:e1002597.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002597
    • Acquaah-Mensah, G.K.1    Malhotra, D.2    Vulimiri, M.3    Mcdermott, J.E.4    Biswal, S.5
  • 4
    • 84942239950 scopus 로고    scopus 로고
    • Efficacy of Vasadi Syrup and Shwasaghna Dhuma in the patients of COPD (Shwasa Roga)
    • SHARMA PK, JOHRI S, MEHRA BL. Efficacy of Vasadi Syrup and Shwasaghna Dhuma in the patients of COPD (Shwasa Roga). Ayu 2010;31:48-52.
    • (2010) Ayu , vol.31 , pp. 48-52
    • Sharma, P.K.1    Johri, S.2    Mehra, B.L.3
  • 5
    • 84884189410 scopus 로고    scopus 로고
    • Integration microarray and regulation datasets for chronic obstructive pulmonary disease
    • YANG JY, JIN J, ZHANG Z, ZHANG L, SHEN C. Integration microarray and regulation datasets for chronic obstructive pulmonary disease. Eur Rev Med Pharmacol Sci 2013, 17:1923-1931.
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , pp. 1923-1931
    • Yang, J.Y.1    Jin, J.2    Zhang, Z.3    Zhang, L.4    Shen, C.5
  • 6
    • 84874879375 scopus 로고    scopus 로고
    • Oxidative/Nitrosative stress and the pathobiology of chronic obstructive pulmonary disease
    • PANDEY R, SINGH M, SINGHAL U, GUPTA KB, AGGARWAL SK. Oxidative/Nitrosative stress and the pathobiology of chronic obstructive pulmonary disease. J Clin Diagn Res 2013;7:580-588.
    • (2013) J Clin Diagn Res , vol.7 , pp. 580-588
    • Pandey, R.1    Singh, M.2    Singhal, U.3    Gupta, K.B.4    Aggarwal, S.K.5
  • 7
    • 18244410118 scopus 로고    scopus 로고
    • The pathogenesis of chronic obstructive pulmonary disease: Advances in the past 100 years
    • SHAPIRO SD, INGENITO EP. The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol 2005;32:367-372.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 367-372
    • Shapiro, S.D.1    Ingenito, E.P.2
  • 9
    • 80052506007 scopus 로고    scopus 로고
    • Lung-targeted overexpression of the NF-κB member RelB inhibits cigarette smoke-induced inflammation
    • MCMILLAN DH, BAGLOLE CJ, THATCHER TH, MAGGIRWAR S, SIME PJ, PHIPPS RP. Lung-targeted overexpression of the NF-κB member RelB inhibits cigarette smoke-induced inflammation. Am J Pathol 2011;179:125-133.
    • (2011) Am J Pathol , vol.179 , pp. 125-133
    • Mcmillan, D.H.1    Baglole, C.J.2    Thatcher, T.H.3    Maggirwar, S.4    Sime, P.J.5    Phipps, R.P.6
  • 12
    • 74849106935 scopus 로고    scopus 로고
    • Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease
    • BARNES PJ. Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6:693-696.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 693-696
    • Barnes, P.J.1
  • 13
    • 79956218469 scopus 로고    scopus 로고
    • Epigenetic control of gene expression in the lung
    • YANG IV, SCHWARTZ DA. Epigenetic control of gene expression in the lung. Am J Respir Crit Care Med 2011;183:1295-1301.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1295-1301
    • Yang, I.V.1    Schwartz, D.A.2
  • 14
    • 80053302944 scopus 로고    scopus 로고
    • The importance of epigenetics in the development of chronic obstructive pulmonary disease
    • SAKAO S, TATSUMI K. The importance of epigenetics in the development of chronic obstructive pulmonary disease. Respirology 2011;16:1056-1063.
    • (2011) Respirology , vol.16 , pp. 1056-1063
    • Sakao, S.1    Tatsumi, K.2
  • 15
    • 84879844307 scopus 로고    scopus 로고
    • Role of epigenetics in inflammationassociated diseases
    • SHANMUGAM MK, SETHI G. Role of epigenetics in inflammationassociated diseases. Subcell Biochem 2012;61:627-657.
    • (2012) Subcell Biochem , vol.61 , pp. 627-657
    • Shanmugam, M.K.1    Sethi, G.2
  • 16
    • 33144482007 scopus 로고    scopus 로고
    • Reduced histone deacetylase in COPD: Clinical implications
    • BARNES PJ. Reduced histone deacetylase in COPD: clinical implications. Chest 2006;129:151-155.
    • (2006) Chest , vol.129 , pp. 151-155
    • Barnes, P.J.1
  • 17
    • 0034931702 scopus 로고    scopus 로고
    • Glucocorticoid-regulated transcription factors
    • ADCOCK IM. Glucocorticoid-regulated transcription factors. Pulm Pharmacol Ther 2001;14:211-219.
    • (2001) Pulm Pharmacol Ther , vol.14 , pp. 211-219
    • Adcock, I.M.1
  • 18
    • 14744285888 scopus 로고    scopus 로고
    • Histone acetylation and deacetylation: Importance in inflammatory lung diseases
    • BARNES PJ, ADCOCK IM, ITO K. Histone acetylation and deacetylation: importance in inflammatory lung diseases. Eur Respir J 2005;25:552-563.
    • (2005) Eur Respir J , vol.25 , pp. 552-563
    • Barnes, P.J.1    Adcock, I.M.2    Ito, K.3
  • 21
    • 84863698643 scopus 로고    scopus 로고
    • Epigenetic alterations in muscular disorders
    • LANZUOLO C. Epigenetic alterations in muscular disorders. Comp Funct Genomics 2012;2012:256892.
    • (2012) Comp Funct Genomics , vol.2012 , pp. 256892
    • Lanzuolo, C.1
  • 22
    • 78650976421 scopus 로고    scopus 로고
    • Epigenetic mechanisms in inflammation
    • BAYARSAIHAN D. Epigenetic mechanisms in inflammation. J Dent Res 2011;90:9-17.
    • (2011) J Dent Res , vol.90 , pp. 9-17
    • Bayarsaihan, D.1
  • 24
    • 79957487252 scopus 로고    scopus 로고
    • Epigenetic mechanisms in diabetic vascular complications
    • REDDY MA, NATARAJAN R. Epigenetic mechanisms in diabetic vascular complications. Cardiovasc Res 2011;90:421-429.
    • (2011) Cardiovasc Res , vol.90 , pp. 421-429
    • Reddy, M.A.1    Natarajan, R.2
  • 25
    • 80054827869 scopus 로고    scopus 로고
    • Transcriptional and epigenetic mechanisms of addiction
    • ROBISON AJ, NESTLER EJ. Transcriptional and epigenetic mechanisms of addiction. Nat Rev Neurosci 2011;12:623-637.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 623-637
    • Robison, A.J.1    Nestler, E.J.2
  • 26
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • KUZARIDES T. Chromatin modifications and their function. Cell 2007;128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kuzarides, T.1
  • 27
    • 84872160505 scopus 로고    scopus 로고
    • DNA methylation, histone modifications, and signal transduction pathways: A close relationship in malignant gliomas pathophysiology
    • ALELU-PAZ R, ASHOUR N, GONZALEZ-CORPAS A, ROPERO S. DNA methylation, histone modifications, and signal transduction pathways: a close relationship in malignant gliomas pathophysiology. J Signal Transduct 2012;2012:956958.
    • (2012) J Signal Transduct , vol.2012 , pp. 956958
    • Alelu-Paz, R.1    Ashour, N.2    Gonzalez-Corpas, A.3    Ropero, S.4
  • 28
    • 84862275407 scopus 로고    scopus 로고
    • Epigenetic regulation of cytokine production in human amnion and villous placenta
    • MITCHELL MD, PONNAMPALAM AP, RICE GE. Epigenetic regulation of cytokine production in human amnion and villous placenta. Mediators Inflamm 2012;2012:159709.
    • (2012) Mediators Inflamm , vol.2012 , pp. 159709
    • Mitchell, M.D.1    Ponnampalam, A.P.2    Rice, G.E.3
  • 29
    • 33947313218 scopus 로고    scopus 로고
    • HDACs, histone deacetylation and gene transcription: From molecular biology to cancer therapeutics
    • GALLINARI P, DI MARCO S, JONES P, PALLAORO M, STEINKUHLER C. HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res 2007;17:195-211.
    • (2007) Cell Res , vol.17 , pp. 195-211
    • Gallinari, P.1    Di Marco, S.2    Jones, P.3    Pallaoro, M.4    Steinkuhler, C.5
  • 31
    • 84865339641 scopus 로고    scopus 로고
    • Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: A promising tool for early detection of COPD and lung cancer in smokers
    • GUZMAN L, DEPIX MS, SALINAS AM, RLDAN R, AGUAYO F, SILVA A, VINET R. Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers. Diagn Pathol 2012;7:87.
    • (2012) Diagn Pathol , vol.7 , pp. 87
    • Guzman, L.1    Depix, M.S.2    Salinas, A.M.3    Rldan, R.4    Aguayo, F.5    Silva, A.6    Vinet, R.7
  • 36
    • 63349102653 scopus 로고    scopus 로고
    • Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke
    • ADENUGA D, YAO H, MARCH TH, SEAGRAVE J, RAHMAN I. Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke. Am J Respir Cell Mol Biol 2009;40:464-473.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 464-473
    • Adenuga, D.1    Yao, H.2    March, T.H.3    Seagrave, J.4    Rahman, I.5
  • 37
    • 38949154571 scopus 로고    scopus 로고
    • Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: Epigenetics in pathogenesis of COPD
    • RAJENDRASOZHAN S, YANG SR, EDIRISINGHE I, YAO H, ADENUGA D, RAHMAN I. Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD. Antioxid Redox Signal 2008;10:799-811.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 799-811
    • Rajendrasozhan, S.1    Yang, S.R.2    Edirisinghe, I.3    Yao, H.4    Adenuga, D.5    Rahman, I.6
  • 38
    • 84878660136 scopus 로고    scopus 로고
    • Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells
    • ZHANG R, KANG KA, KIM KC, NA SY, CHANG WY, KIM GY, KIM HS, HYUN JW. Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells. Gene 2013;524:214-219.
    • (2013) Gene , vol.524 , pp. 214-219
    • Zhang, R.1    Kang, K.A.2    Kim, K.C.3    Na, S.Y.4    Chang, W.Y.5    Kim, G.Y.6    Kim, H.S.7    Hyun, J.W.8
  • 40
    • 84860269756 scopus 로고    scopus 로고
    • Epigenetic changes induced by oxidative stress in colorectal cancer cells: Methylation of tumor suppressor RUNX3
    • KANG KA, ZHANG R, KIM GY, BAE SC, HYUN JW. Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3. Tumour Biol 2012;33:403-412.
    • (2012) Tumour Biol , vol.33 , pp. 403-412
    • Kang, K.A.1    Zhang, R.2    Kim, G.Y.3    Bae, S.C.4    Hyun, J.W.5
  • 41
    • 84862950110 scopus 로고    scopus 로고
    • Hypoxia-derived oxidative stress mediates epigenetic repression of PKCε gene in foetal rat hearts
    • PATTERSON AJ, XIAO D, XIONG F, DIXON B, ZHANG L. Hypoxia-derived oxidative stress mediates epigenetic repression of PKCε gene in foetal rat hearts. Cardiovasc Res 2012;93:302-310.
    • (2012) Cardiovasc Res , vol.93 , pp. 302-310
    • Patterson, A.J.1    Xiao, D.2    Xiong, F.3    Dixon, B.4    Zhang, L.5
  • 42
    • 84857824527 scopus 로고    scopus 로고
    • Parvovirus b19 DNA CpG dinucleotide methylation and epigenetic regulation of viral expression
    • BONVICINI F, MANARESI E, DI FURIO F, DE FALCO L, GALLINELLA G. Parvovirus b19 DNA CpG dinucleotide methylation and epigenetic regulation of viral expression. PLoS One 2012;7:e33316.
    • (2012) PLoS One , vol.7 , pp. e33316
    • Bonvicini, F.1    Manaresi, E.2    Di Furio, F.3    De Falco, L.4    Gallinella, G.5
  • 43
    • 84863277519 scopus 로고    scopus 로고
    • DNA methylation and microRNAs in cancer
    • LI XQ, GUO YY, DE W. DNA methylation and microRNAs in cancer. World J Gastroenterol 2012;18:882-888.
    • (2012) World J Gastroenterol , vol.18 , pp. 882-888
    • Li, X.Q.1    Guo, Y.Y.2    De, W.3
  • 45
    • 84863757162 scopus 로고    scopus 로고
    • Epigenetic modifications in frontal cor tex from Alzheimer's disease and bipolar disorder patients
    • RAO JS, KELESHIAN VL, KLEIN S, RAPOPORT SI. Epigenetic modifications in frontal cor tex from Alzheimer's disease and bipolar disorder patients. Transl Psychiatry 2012;2:e132.
    • (2012) Transl Psychiatry , vol.2 , pp. e132
    • Rao, J.S.1    Keleshian, V.L.2    Klein, S.3    Rapoport, S.I.4
  • 46
    • 84864053192 scopus 로고    scopus 로고
    • Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
    • ORR BA, HAFFNER MC, NELSON WG, YEGNASUBRAMANIAN S, EBERHART CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. PLoS One 2012;7:e41036.
    • (2012) PLoS One , vol.7 , pp. e41036
    • Orr, B.A.1    Haffner, M.C.2    Nelson, W.G.3    Yegnasubramanian, S.4    Eberhart, C.G.5
  • 47
    • 14844307097 scopus 로고    scopus 로고
    • Epigenetic regulation by histone methylation and histone variants
    • CHEUNG P, LAU P. Epigenetic regulation by histone methylation and histone variants. Mol Endocrinol 2005;19:563-573.
    • (2005) Mol Endocrinol , vol.19 , pp. 563-573
    • Cheung, P.1    Lau, P.2
  • 48
    • 84863795851 scopus 로고    scopus 로고
    • Epigenetics of hepatocellular carcinoma: A new horizon
    • LIU WR, SHI YH, PENG YF, FAN J. Epigenetics of hepatocellular carcinoma: a new horizon. Chin Med J (Engl) 2012;125:2349-2360.
    • (2012) Chin Med J (Engl) , vol.125 , pp. 2349-2360
    • Liu, W.R.1    Shi, Y.H.2    Peng, Y.F.3    Fan, J.4
  • 51
    • 80053443628 scopus 로고    scopus 로고
    • A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequencespecific binding protein
    • BARTELS SJ, SPRUIJT CG, BRINKMAN AB, JANSEN PW, VERMEULEN M, STUNNENBERG HG. A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequencespecific binding protein. PLoS One 2011;6:e25884.
    • (2011) PLoS One , vol.6 , pp. e25884
    • Bartels, S.J.1    Spruijt, C.G.2    Brinkman, A.B.3    Jansen, P.W.4    Vermeulen, M.5    Stunnenberg, H.G.6
  • 52
    • 80054790280 scopus 로고    scopus 로고
    • The roles of the methyl-CpG binding proteins in cancer
    • PARRY L, CLARKE AR. The roles of the methyl-CpG binding proteins in cancer. Genes Cancer 2011;2:618-630.
    • (2011) Genes Cancer , vol.2 , pp. 618-630
    • Parry, L.1    Clarke, A.R.2
  • 53
    • 79957873677 scopus 로고    scopus 로고
    • Epigenetic regulation in alcoholic liver disease
    • MANDREKAR P. Epigenetic regulation in alcoholic liver disease. World J Gastroenterol 2011;17:2456-2464.
    • (2011) World J Gastroenterol , vol.17 , pp. 2456-2464
    • Mandrekar, P.1
  • 55
    • 84862027801 scopus 로고    scopus 로고
    • Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene Cadm1
    • REAMON-BUETTNER SM, BORLAK J. Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene Cadm1. PLoS One 2012;7:e38531.
    • (2012) PLoS One , vol.7 , pp. e38531
    • Reamon-Buettner, S.M.1    Borlak, J.2
  • 56
    • 84862282178 scopus 로고    scopus 로고
    • Epigenetic dysregulation in laryngeal squamous cell carcinoma
    • WONG TS, GAO W, LI ZH, CHAN JY, HO WK. Epigenetic dysregulation in laryngeal squamous cell carcinoma. J Oncol 2012;2012:739461.
    • (2012) J Oncol , vol.2012 , pp. 739461
    • Wong, T.S.1    Gao, W.2    Li, Z.H.3    Chan, J.Y.4    Ho, W.K.5
  • 57
    • 0024081657 scopus 로고
    • Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
    • WATT F, MOLLOY PL. Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev 1988;2:1136-1143.
    • (1988) Genes Dev , vol.2 , pp. 1136-1143
    • Watt, F.1    Molloy, P.L.2
  • 59
    • 0035339188 scopus 로고    scopus 로고
    • MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome
    • WAN M, ZHAO K, LEE SS, FRANCKE U. MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome. Hum Mol Genet 2001;10:1085-1092.
    • (2001) Hum Mol Genet , vol.10 , pp. 1085-1092
    • Wan, M.1    Zhao, K.2    Lee, S.S.3    Francke, U.4
  • 60
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • ROBERTSON KD. DNA methylation and human disease. Nat Rev Genet 2005;6:597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 61
  • 62
    • 84555189793 scopus 로고    scopus 로고
    • Roles of apoptosis, cell senescence, and DNA damage in the pathogenetic mechanism of COPD
    • AOSHIBA K. Roles of apoptosis, cell senescence, and DNA damage in the pathogenetic mechanism of COPD. Nihon Rinsho 2011;69:1754-1757.
    • (2011) Nihon Rinsho , vol.69 , pp. 1754-1757
    • Aoshiba, K.1
  • 63
    • 84877098219 scopus 로고    scopus 로고
    • Airway epithelial cell apoptosis and inflammation in COPD, smokers and nonsmokers
    • COMER DM, KIDNEY JC, ENNIS M, ELBORN JS. Airway epithelial cell apoptosis and inflammation in COPD, smokers and nonsmokers. Eur Respir J 2013;41:1058-1067.
    • (2013) Eur Respir J , vol.41 , pp. 1058-1067
    • Comer, D.M.1    Kidney, J.C.2    Ennis, M.3    Elborn, J.S.4
  • 66
    • 84855174717 scopus 로고    scopus 로고
    • Cytochrome C oxidase expression and endothelial cell apoptosis in lungs of patients with chronic obstructive pulmonary disease
    • YANG M, CHEN P, PENG H, SHEN Q, CHEN Y. Cytochrome C oxidase expression and endothelial cell apoptosis in lungs of patients with chronic obstructive pulmonary disease. Zhonghua Jie He He Hu Xi Za Zhi 2010;33:665-669.
    • (2010) Zhonghua Jie He He Hu Xi Za Zhi , vol.33 , pp. 665-669
    • Yang, M.1    Chen, P.2    Peng, H.3    Shen, Q.4    Chen, Y.5
  • 67
    • 84942264030 scopus 로고    scopus 로고
    • Involvement of DNA methylation in endothelial apoptosis induced by cigarette smoke extract
    • 20th ERS Annual Congress, Barcelona, Spain, 18th-22nd September 2010
    • YANG M, PENG H, CHEN P. Involvement of DNA methylation in endothelial apoptosis induced by cigarette smoke extract. Eur Respir J 2010;36(Supplement 54):20th ERS Annual Congress, Barcelona, Spain, 18th-22nd September 2010.
    • (2010) Eur Respir J , vol.36
    • Yang, M.1    Peng, H.2    Chen, P.3
  • 68
    • 84942264031 scopus 로고    scopus 로고
    • The effect of mtTFA methylation in the pathogenesis of pulmonary vascular endothelial cell apoptosis of chronic obstructive pulmonary disease
    • 20th ERS Annual Congress, Barcelona, Spain, 18th-22nd September 2010
    • PENG H, YANG M, CHEN P. The effect of mtTFA methylation in the pathogenesis of pulmonary vascular endothelial cell apoptosis of chronic obstructive pulmonary disease. Eur Respir J 2010;36(Supplement 54):20th ERS Annual Congress, Barcelona, Spain, 18th-22nd September 2010.
    • (2010) Eur Respir J , vol.36
    • Peng, H.1    Yang, M.2    Chen, P.3
  • 69
    • 78650621692 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics
    • YAP JL, WORLIKAR S, MACKERELL AD JR, SHAPIRO P, FLETCHER S. Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics. Chem Med Chem 2011;6:38-48.
    • (2011) Chem Med Chem , vol.6 , pp. 38-48
    • Yap, J.L.1    Worlikar, S.2    Mackerell, A.D.3    Shapiro, P.4    Fletcher, S.5
  • 70
    • 80054862895 scopus 로고    scopus 로고
    • Role of extracellular signal-regulated kinase 1/2 in cigarette smoke-induced mucus hypersecretion in a rat model
    • XIAO J, WANG K, FENG YL, CHEN XR, XU D, ZHANG MK. Role of extracellular signal-regulated kinase 1/2 in cigarette smoke-induced mucus hypersecretion in a rat model. Chin Med J (Engl) 2011;124:3327-3333.
    • (2011) Chin Med J (Engl) , vol.124 , pp. 3327-3333
    • Xiao, J.1    Wang, K.2    Feng, Y.L.3    Chen, X.R.4    Xu, D.5    Zhang, M.K.6
  • 71
    • 84877882444 scopus 로고    scopus 로고
    • Change of extracellular signal-regulated kinase expression in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease
    • LIU K, LIU XS, YU MQ, XU YJ. Change of extracellular signal-regulated kinase expression in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease. Exp Lung Res 2013;39:162-172.
    • (2013) Exp Lung Res , vol.39 , pp. 162-172
    • Liu, K.1    Liu, X.S.2    Yu, M.Q.3    Xu, Y.J.4
  • 72
    • 76749144208 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase (ERK) inhibition attenuates cigarette smoke extract (CSE) induced-death inducing signaling complex (DISC) formation in human lung fibroblasts (MRC-5) cells
    • PARK JW, YOON JY, KIMYJ, KYUNG SY, LEE SP, JEONG SH, MOON C. Extracellular signal-regulated kinase (ERK) inhibition attenuates cigarette smoke extract (CSE) induced-death inducing signaling complex (DISC) formation in human lung fibroblasts (MRC-5) cells. J Toxicol Sci 2010;35:33-39.
    • (2010) J Toxicol Sci , vol.35 , pp. 33-39
    • Park, J.W.1    Yoon, J.Y.2    Kimy, J.3    Kyung, S.Y.4    Lee, S.P.5    Jeong, S.H.6    Moon, C.7
  • 73
    • 67349170402 scopus 로고    scopus 로고
    • Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1
    • HSU CL, WU YL, TANG GJ, LEE TS, KOU YR. Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1. Pulm Pharmacol Ther 2009;22:286-296.
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 286-296
    • Hsu, C.L.1    Wu, Y.L.2    Tang, G.J.3    Lee, T.S.4    Kou, Y.R.5
  • 74
    • 3042678551 scopus 로고    scopus 로고
    • Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression
    • OELKE K, RICHARDSON B. Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression. Int Rev Immunol 2004;23:315-331
    • (2004) Int Rev Immunol , vol.23 , pp. 315-331
    • Oelke, K.1    Richardson, B.2
  • 75
    • 34249705328 scopus 로고    scopus 로고
    • Inhibition of the extracellular signal-regulatied kinase/mitogen-actived protein kinase pathway decrease DNA methylation in colon cancer cell
    • LU R, WANG X, CHEN ZF, SUN DF, TIAN XQ, FANG JY. Inhibition of the extracellular signal-regulatied kinase/mitogen-actived protein kinase pathway decrease DNA methylation in colon cancer cell. J Biol Chem 2007;282:12249-12259
    • (2007) J Biol Chem , vol.282 , pp. 12249-12259
    • Lu, R.1    Wang, X.2    Chen, Z.F.3    Sun, D.F.4    Tian, X.Q.5    Fang, J.Y.6
  • 76
    • 80051974241 scopus 로고    scopus 로고
    • NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs
    • CHUNG S, SUNDAR IK, HWANG JW, YULL FE, BLACKWELL TS, KINNULA VL, BULGER M, YAO H, RAHMAN I. NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs. PLoS One 2011;6:e23488.
    • (2011) PLoS One , vol.6 , pp. e23488
    • Chung, S.1    Sundar, I.K.2    Hwang, J.W.3    Yull, F.E.4    Blackwell, T.S.5    Kinnula, V.L.6    Bulger, M.7    Yao, H.8    Rahman, I.9
  • 77
    • 74949088495 scopus 로고    scopus 로고
    • Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: A critical role of p50 in chromatin remodeling
    • RAJENDRASOZHAN S, CHUNG S, SUNDAR IK, YAO H, RAHMAN I. Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol 2010;298:L197-L209.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , pp. L197-L209
    • Rajendrasozhan, S.1    Chung, S.2    Sundar, I.K.3    Yao, H.4    Rahman, I.5
  • 78
    • 79958820786 scopus 로고    scopus 로고
    • Lung cancer and its association with chronic obstructive pulmonary disease: Update on nexus of epigenetics
    • SUNDAR IK, MULLAPUDI N, YAO H, SPIVACK SD, RAHMAN I. Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics. Curr Opin Pulm Med 2011;17:279-85.
    • (2011) Curr Opin Pulm Med , vol.17 , pp. 279-285
    • Sundar, I.K.1    Mullapudi, N.2    Yao, H.3    Spivack, S.D.4    Rahman, I.5
  • 80
    • 79958189845 scopus 로고    scopus 로고
    • Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation
    • GHIZZONI M, HAISMA HJ, MAARSINGH H, DEKKER FJ. Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation. Drug Discov Today 2011;16:504-511.
    • (2011) Drug Discov Today , vol.16 , pp. 504-511
    • Ghizzoni, M.1    Haisma, H.J.2    Maarsingh, H.3    Dekker, F.J.4
  • 81
    • 79952728721 scopus 로고    scopus 로고
    • Oxidative stress, thiol redox signaling methods in epigenetics
    • SUNDAR IK, CAITO S, YAO H, RAHMAN I. Oxidative stress, thiol redox signaling methods in epigenetics. Methods Enzymol 2010;474:213-244.
    • (2010) Methods Enzymol , vol.474 , pp. 213-244
    • Sundar, I.K.1    Caito, S.2    Yao, H.3    Rahman, I.4
  • 82
    • 4143070452 scopus 로고    scopus 로고
    • Redox modulation of chromatin remodeling: Impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression
    • RAHMAN I, MARWICK J, KIRKHAM P. Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression. Biochem Pharmacol 2004;68:1255-1267.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1255-1267
    • Rahman, I.1    Marwick, J.2    Kirkham, P.3
  • 83
    • 84555187916 scopus 로고    scopus 로고
    • Purification of multiprotein histone acetyltransferase complexes
    • WANG YL, FAIOLA F, MARTINEZ E. Purification of multiprotein histone acetyltransferase complexes. Methods Mol Biol 2012;809:427-443.
    • (2012) Methods Mol Biol , vol.809 , pp. 427-443
    • Wang, Y.L.1    Faiola, F.2    Martinez, E.3
  • 84
    • 78649894738 scopus 로고    scopus 로고
    • Histone acetylation modulation by small molecules: A chemical approach
    • REKOWSKI MW, GIANNIS A. Histone acetylation modulation by small molecules: a chemical approach. Biochim Biophys Acta 2010;1799:760-767.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 760-767
    • Rekowski, M.W.1    Giannis, A.2
  • 85
    • 84863187331 scopus 로고    scopus 로고
    • Is histone acetylation the most important physiological function for CBP and p300?
    • BEDFORD DC, BRINDLE PK. Is histone acetylation the most important physiological function for CBP and p300? Aging (Albany NY) 2012;4:247-255.
    • (2012) Aging (Albany NY) , vol.4 , pp. 247-255
    • Bedford, D.C.1    Brindle, P.K.2
  • 87
    • 0038544188 scopus 로고    scopus 로고
    • Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases
    • RAHMAN I. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J Biochem Mol Biol 2003;36:95-109.
    • (2003) J Biochem Mol Biol , vol.36 , pp. 95-109
    • Rahman, I.1
  • 88
    • 70350433679 scopus 로고    scopus 로고
    • Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD
    • RAJENDRASOZHAN S, YAO H, RAHMAN I. Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD. COPD 2009;6:291-297.
    • (2009) COPD , vol.6 , pp. 291-297
    • Rajendrasozhan, S.1    Yao, H.2    Rahman, I.3
  • 89
    • 34547896665 scopus 로고    scopus 로고
    • COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1
    • CAO D, BROMBERG PA, SAMET JM. COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1. Am J Respir Cell Mol Biol 2007;37:232-239.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 232-239
    • Cao, D.1    Bromberg, P.A.2    Samet, J.M.3
  • 90
    • 39649094273 scopus 로고    scopus 로고
    • Endothelin-1 increases expression of cyclooxygenase-2 and production of interlukin-8 in hunan pulmonary epithelial cells
    • PENG H, CHEN P, CAI Y, CHEN Y, WU QH, LI Y, ZHOU R, FANG X. Endothelin-1 increases expression of cyclooxygenase-2 and production of interlukin-8 in hunan pulmonary epithelial cells. Peptides 2008;29:419-424.
    • (2008) Peptides , vol.29 , pp. 419-424
    • Peng, H.1    Chen, P.2    Cai, Y.3    Chen, Y.4    Wu, Q.H.5    Li, Y.6    Zhou, R.7    Fang, X.8
  • 91
    • 80052180405 scopus 로고    scopus 로고
    • Class IIa HDACs: From important roles in differentiation to possible implications in tumourigenesis
    • CLOCCHIATTI A, FLOREAN C, BRANCOLINI C. Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis. J Cell Mol Med 2011;15:1833-1846.
    • (2011) J Cell Mol Med , vol.15 , pp. 1833-1846
    • Clocchiatti, A.1    Florean, C.2    Brancolini, C.3
  • 92
    • 84855471990 scopus 로고    scopus 로고
    • HDAC inhibitors in cancer biology: Emerging mechanisms and clinical applications
    • KHAN O, LA THANGUE NB. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol Cell Biol 2012;90:85-94.
    • (2012) Immunol Cell Biol , vol.90 , pp. 85-94
    • Khan, O.1    La Thangue, N.B.2
  • 93
    • 79251544228 scopus 로고    scopus 로고
    • Regulating the regulators: The post-translational code of class I HDAC1 and HDAC2
    • SEGRE CV, CHIOCCA S. Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2. J Biomed Biotechnol 2011;2011:690848.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 690848
    • Segre, C.V.1    Chiocca, S.2
  • 94
    • 79951881254 scopus 로고    scopus 로고
    • Protective roles of SIRT1 in atherosclerosis
    • STEIN S, MATTER CM. Protective roles of SIRT1 in atherosclerosis. Cell Cycle 2011;10:640-647.
    • (2011) Cell Cycle , vol.10 , pp. 640-647
    • Stein, S.1    Matter, C.M.2
  • 96
    • 84863135417 scopus 로고    scopus 로고
    • Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow
    • LEE DY, LEE CI, LIN TE, LIM SH, ZHOU J, TSENG YC, CHIEN S, CHIU JJ. Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow. Proc Natl Acad Sci U S A 2012;109:1967-1972.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 1967-1972
    • Lee, D.Y.1    Lee, C.I.2    Lin, T.E.3    Lim, S.H.4    Zhou, J.5    Tseng, Y.C.6    Chien, S.7    Chiu, J.J.8
  • 97
    • 79957900741 scopus 로고    scopus 로고
    • Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease
    • YAO H, RAHMAN I. Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease. Toxicol Appl Pharmacol 2011;254:72-85.
    • (2011) Toxicol Appl Pharmacol , vol.254 , pp. 72-85
    • Yao, H.1    Rahman, I.2
  • 98
    • 79955090868 scopus 로고    scopus 로고
    • Patterns of inflammatory responses in large and small airways in smokers with and without chronic obstructive pulmonary disease
    • ISAJEVS S, TAIVANS I, SVIRINA D, STRAZDA G, KOPEIKA U. Patterns of inflammatory responses in large and small airways in smokers with and without chronic obstructive pulmonary disease. Respiration 2011;81:362-371.
    • (2011) Respiration , vol.81 , pp. 362-371
    • Isajevs, S.1    Taivans, I.2    Svirina, D.3    Strazda, G.4    Kopeika, U.5
  • 99
    • 84862788383 scopus 로고    scopus 로고
    • Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD
    • CHEN Y, HUANG P, AI W, LI X, GUO W, ZHANG J, YANG J. Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD. J Inflamm (Lond) 2012;9:10.
    • (2012) J Inflamm (Lond) , vol.9 , pp. 10
    • Chen, Y.1    Huang, P.2    Ai, W.3    Li, X.4    Guo, W.5    Zhang, J.6    Yang, J.7
  • 100
    • 34548856201 scopus 로고    scopus 로고
    • Impact of protein acetylation in inflammatory lung diseases
    • ITO K, CHARRON CE, ADCOCK IM. Impact of protein acetylation in inflammatory lung diseases. Pharmacol Ther 2007;116:249-265.
    • (2007) Pharmacol Ther , vol.116 , pp. 249-265
    • Ito, K.1    Charron, C.E.2    Adcock, I.M.3
  • 101
    • 0036066957 scopus 로고    scopus 로고
    • Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: Potential mechanism in gene transcription in lung inflammation
    • RAHMAN I, GILMOUR PS, JIMENEZ LA, MACNEE W. Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. Mol Cell Biochem 2002;234-235:239-248.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 239-248
    • Rahman, I.1    Gilmour, P.S.2    Jimenez, L.A.3    Macnee, W.4
  • 103
    • 10044241543 scopus 로고    scopus 로고
    • Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells
    • MOODIE FM, MARWICK JA, ANDERSON CS, SZULAKOWSKI P, BISWAS SK, BAUTER MR, KILTY I, RAHMAN I. Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells. FASEB J, 2004;18:1897-1899.
    • (2004) FASEB J , vol.18 , pp. 1897-1899
    • Moodie, F.M.1    Marwick, J.A.2    Anderson, C.S.3    Szulakowski, P.4    Biswas, S.K.5    Bauter, M.R.6    Kilty, I.7    Rahman, I.8
  • 104
    • 33745099273 scopus 로고    scopus 로고
    • Histone deacetylation: An important mechanism in inflammatory lung diseases
    • ADCOCK IM, ITO K, BARNES PJ. Histone deacetylation: an important mechanism in inflammatory lung diseases. COPD, 2005;2:445-455.
    • (2005) COPD , vol.2 , pp. 445-455
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 106
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
    • ITO K, YAMAMURA S, ESSILFIE-QUAYE S, COSIO B, ITO M, BARNES PJ, ADCOCK IM. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 2006;203:7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 107
    • 27644572664 scopus 로고    scopus 로고
    • Glucocorticoid pathways in chronic obstructive pulmonary disease therapy
    • ADCOCK IM, ITO K. Glucocorticoid pathways in chronic obstructive pulmonary disease therapy. Proc Am Thorac Soc 2005;2:313-319.
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 313-319
    • Adcock, I.M.1    Ito, K.2
  • 108
    • 33947482638 scopus 로고
    • The occurrence of ε-N-methyl lysine in histones in histones
    • MURRAY K. The occurrence of ε-N-methyl lysine in histones in histones. Biochemistry, 1964;3:10-15.
    • (1964) Biochemistry , vol.3 , pp. 10-15
    • Murray, K.1
  • 112
    • 25144459091 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a
    • MIRANDA TB, WEBB KJ, EDBERG DD, REEVES R, CLARKE S. Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a. Biochem Biophys Res Commun 2005;336:831-835.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 831-835
    • Miranda, T.B.1    Webb, K.J.2    Edberg, D.D.3    Reeves, R.4    Clarke, S.5
  • 113
    • 84867760865 scopus 로고    scopus 로고
    • Protein arginine methyltransferases (PRMTs): Promising targets for the treatment of pulmonary disorders
    • ZAKRZEWICZ D, ZAKRZEWICZ A, PREISSNER KT, MARKART P, WYGRECKA M. Protein arginine methyltransferases (PRMTs): promising targets for the treatment of pulmonary disorders. Int J Mol Sci 2012;13:12383-12400.
    • (2012) Int J Mol Sci , vol.13 , pp. 12383-12400
    • Zakrzewicz, D.1    Zakrzewicz, A.2    Preissner, K.T.3    Markart, P.4    Wygrecka, M.5
  • 114
    • 84875221875 scopus 로고    scopus 로고
    • Novel symmetrical ureas as modulators of protein arginine methyl transferases
    • FONTAN N, GARCIA-DOMINGUEZ P, ALVAREZ R, DE LERA AR. Novel symmetrical ureas as modulators of protein arginine methyl transferases. Bioorg Med Chem 2013;21:2056-2067.
    • (2013) Bioorg Med Chem , vol.21 , pp. 2056-2067
    • Fontan, N.1    Garcia-Dominguez, P.2    Alvarez, R.3    De Lera, A.R.4
  • 115
    • 67650334164 scopus 로고    scopus 로고
    • Characterization of PRMT1 from Plasmodium falciparum
    • FAN Q, MIAO J, CUI L, CUI L. Characterization of PRMT1 from Plasmodium falciparum. Biochem J 2009;421:107-118
    • (2009) Biochem J , vol.421 , pp. 107-118
    • Fan, Q.1    Miao, J.2    Cui, L.3    Cui, L.4
  • 116
    • 60849089926 scopus 로고    scopus 로고
    • From arginine methylation to ADMA: A novel mechanism with therapeutic potential in chronic lung diseases
    • ZAKRZEWICZ D, EICKELBERG O. From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC Pulm Med 2009;9:5.
    • (2009) BMC Pulm Med , vol.9 , pp. 5
    • Zakrzewicz, D.1    Eickelberg, O.2
  • 117
    • 48049085735 scopus 로고    scopus 로고
    • Serum asymmetric dimethylarginine levels among Turks: Association with metabolic syndrome in women and tendency to decrease in smokers
    • ONAT A, HERGENC G, CAN G, KARABULUT A. Serum asymmetric dimethylarginine levels among Turks: association with metabolic syndrome in women and tendency to decrease in smokers. Turk Kardiyol Dern Ars 2008;36:7-13.
    • (2008) Turk Kardiyol Dern Ars , vol.36 , pp. 7-13
    • Onat, A.1    Hergenc, G.2    Can, G.3    Karabulut, A.4
  • 118
    • 9344254366 scopus 로고    scopus 로고
    • Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine
    • EID HM, ARNESEN H, HJERKINN EM, LYBERG T, SELJEFLOT I. Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine. Metabolism 2004;53:1574-1579.
    • (2004) Metabolism , vol.53 , pp. 1574-1579
    • Eid, H.M.1    Arnesen, H.2    Hjerkinn, E.M.3    Lyberg, T.4    Seljeflot, I.5
  • 119
    • 34147194549 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine, smoking, and risk of coronary hear t disease in apparently healthy men: Prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data
    • MAAS R, SCHULZE F, BAUMERT J, LOWEL H, HAMRAZ K, SCHWEDHELM E, KOENIG W, BOGER RH. Asymmetric dimethylarginine, smoking, and risk of coronary hear t disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data. Clin Chem 2007;53:693-701.
    • (2007) Clin Chem , vol.53 , pp. 693-701
    • Maas, R.1    Schulze, F.2    Baumert, J.3    Lowel, H.4    Hamraz, K.5    Schwedhelm, E.6    Koenig, W.7    Boger, R.H.8
  • 120
    • 33748177479 scopus 로고    scopus 로고
    • Adverse effects of cigarette smoke on NO bioavailability: Role of arginine metabolism and oxidative stress
    • ZHANG WZ, VENARDOS K, CHIN-DUSTING J, KAYE DM. Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress. Hypertension 2006;48:278-285.
    • (2006) Hypertension , vol.48 , pp. 278-285
    • Zhang, W.Z.1    Venardos, K.2    Chin-Dusting, J.3    Kaye, D.M.4
  • 121
    • 84988245261 scopus 로고    scopus 로고
    • Expression Profiling of Protein Arginine Methyltransferase (Prmt) Isoforms in Chronic Obstructive Pulmonary Disease (COPD)
    • YILDIRIM AQ, KONIGSHOFF M, WANG Q, EICKELBERG O. Expression Profiling Of Protein Arginine Methyltransferase (Prmt) Isoforms In Chronic Obstructive Pulmonary Disease (COPD). Am J Respir Crit Care Med 2010;181:A4954.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. A4954
    • Yildirim, A.Q.1    Konigshoff, M.2    Wang, Q.3    Eickelberg, O.4
  • 124
    • 0034698038 scopus 로고    scopus 로고
    • LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: Involvement of S-adenosylmethionine-dependent methyltransferases
    • BOGER RH, SYDOW K, BORLAK J, THUM T, LENZEN H, SCHUBERT B, TSIKAS D, BODE-BOGER SM. LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases. Circ Res 2000;87:99-105.
    • (2000) Circ Res , vol.87 , pp. 99-105
    • Boger, R.H.1    Sydow, K.2    Borlak, J.3    Thum, T.4    Lenzen, H.5    Schubert, B.6    Tsikas, D.7    Bode-Boger, S.M.8
  • 125
    • 79960469576 scopus 로고    scopus 로고
    • Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease
    • ANDRESEN E, GUNTHER G, BULLWINKEL J, LANGE C, HEINE H. Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease. PLoS One 2011;6:e21898.
    • (2011) PLoS One , vol.6 , pp. e21898
    • Andresen, E.1    Gunther, G.2    Bullwinkel, J.3    Lange, C.4    Heine, H.5
  • 126
    • 34249809436 scopus 로고    scopus 로고
    • Role of histone phosphorylation in chromatin dynamics and its implications in diseases
    • OKI M, AIHARA H, ITO T. Role of histone phosphorylation in chromatin dynamics and its implications in diseases. Subcell Biochem 2007;41:319-336.
    • (2007) Subcell Biochem , vol.41 , pp. 319-336
    • Oki, M.1    Aihara, H.2    Ito, T.3
  • 127
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • BANNISTER AJ, KOUZARIDES T. Regulation of chromatin by histone modifications. Cell Res 2011;21:381-395.
    • (2011) Cell Res , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 129
    • 0036158780 scopus 로고    scopus 로고
    • Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation
    • GOTO H, YASUI Y, NIGG EA, INAGAKI M. Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells 2002;7:11-17.
    • (2002) Genes Cells , vol.7 , pp. 11-17
    • Goto, H.1    Yasui, Y.2    Nigg, E.A.3    Inagaki, M.4
  • 133
    • 84856409891 scopus 로고    scopus 로고
    • Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes
    • SUNDAR IK, CHUNG S, HWANG JW, LAPEK JD JR, BULGER M, FRIEDMAN AE, YAO H, DAVIE JR, RAHman I. Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes. PLoS One 2012;7:e31378.
    • (2012) PLoS One , vol.7 , pp. e31378
    • Sundar, I.K.1    Chung, S.2    Hwang, J.W.3    Lapek, J.D.4    Bulger, M.5    Friedman, A.E.6    Yao, H.7    Davie, J.R.8    Rahman, I.9
  • 134
    • 33750627155 scopus 로고    scopus 로고
    • Alveolar macrophages as orchestrators of COPD
    • BARNES PJ. Alveolar macrophages as orchestrators of COPD. COPD 2004;1:59-70.
    • (2004) COPD , vol.1 , pp. 59-70
    • Barnes, P.J.1
  • 138
    • 1542284710 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase modulation of nuclear factorkappaB-induced granulocyte macrophagecolonystimulating factor release from human alveolar macrophages
    • KOCH A, GIEMBYCZ M, ITO K, LIM S, JAZRAWI E, BARNES PJ, ADCOCK I, ERDMANN E, CHUNG KF. Mitogen-activated protein kinase modulation of nuclear factorkappaB-induced granulocyte macrophagecolonystimulating factor release from human alveolar macrophages. Am J Respir Cell Mol Biol 2004;30:342-349.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 342-349
    • Koch, A.1    Giembycz, M.2    Ito, K.3    Lim, S.4    Jazrawi, E.5    Barnes, P.J.6    Adcock, I.7    Erdmann, E.8    Chung, K.F.9
  • 139
    • 23244438717 scopus 로고    scopus 로고
    • Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: Cellular and molecular mechanisms
    • RAHMAN I. Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms. Cell Biochem Biophys 2005;43:167-188.
    • (2005) Cell Biochem Biophys , vol.43 , pp. 167-188
    • Rahman, I.1
  • 141
    • 82955187699 scopus 로고    scopus 로고
    • Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease
    • JU CR, CHEN RC. Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease. Respir Med 2012;106:102-108.
    • (2012) Respir Med , vol.106 , pp. 102-108
    • Ju, C.R.1    Chen, R.C.2
  • 143
    • 84866549876 scopus 로고    scopus 로고
    • Sarcopenia and cachexia: The adaptations of negative regulators of skeletal muscle mass
    • SAKUMA K, YAMAGUCHI A. Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass. J Cachexia Sarcopenia Muscle 2012;3:77-94.
    • (2012) J Cachexia Sarcopenia Muscle , vol.3 , pp. 77-94
    • Sakuma, K.1    Yamaguchi, A.2
  • 144
    • 84878607968 scopus 로고    scopus 로고
    • Role of autophagy in COPD skeletal muscle dysfunction
    • HUSSAIN SN, SANDRI M. Role of autophagy in COPD skeletal muscle dysfunction. J Appl Physiol 2013;114:1273-1281.
    • (2013) J Appl Physiol , vol.114 , pp. 1273-1281
    • Hussain, S.N.1    Sandri, M.2
  • 146
    • 77953283124 scopus 로고    scopus 로고
    • Ubiquitination and proteolysis in limb and respiratory muscles of patients with chronic obstructive pulmonary disease
    • DEBIGARE R, COTE CH, MALTAIS F. Ubiquitination and proteolysis in limb and respiratory muscles of patients with chronic obstructive pulmonary disease. Proc Am Thorac Soc 2010;7:84-90.
    • (2010) Proc Am Thorac Soc , vol.7 , pp. 84-90
    • Debigare, R.1    Cote, C.H.2    Maltais, F.3
  • 147
    • 36148987237 scopus 로고    scopus 로고
    • Factors contributing to muscle wasting and dysfunction in COPD patients
    • WUST RC, DEGENS H. Factors contributing to muscle wasting and dysfunction in COPD patients. Int J Chron Obstruct Pulmon Dis 2007;2:289-300.
    • (2007) Int J Chron Obstruct Pulmon Dis , vol.2 , pp. 289-300
    • Wust, R.C.1    Degens, H.2
  • 148
    • 84860388930 scopus 로고    scopus 로고
    • Cigarette smoke-induced skeletal muscle atrophy is associated with upregulation of USP-19 via p38 and ERK MAPKs
    • LIU Q, XU WG, LUO Y, HAN FF, YAO XH, YANG TY, ZHANG Y, PI WF, GUO XJ. Cigarette smoke-induced skeletal muscle atrophy is associated with upregulation of USP-19 via p38 and ERK MAPKs. J Cell Biochem 2011;112:2307-2316.
    • (2011) J Cell Biochem , vol.112 , pp. 2307-2316
    • Liu, Q.1    Xu, W.G.2    Luo, Y.3    Han, F.F.4    Yao, X.H.5    Yang, T.Y.6    Zhang, Y.7    Pi, W.F.8    Guo, X.J.9
  • 153
    • 80051541985 scopus 로고    scopus 로고
    • Acyl-CoA: Lysophosphatidylcholine acyltransferase I (Lpcat1) catalyzes histone protein O-palmitoylation to regulate mRNA synthesis
    • ZOU C, ELLIS BM, SMITH RM, CHEN BB, ZHAO Y, MALLAMPALLI RK. Acyl-CoA: lysophosphatidylcholine acyltransferase I (Lpcat1) catalyzes histone protein O-palmitoylation to regulate mRNA synthesis. J Biol Chem 2011;286:28019-28025.
    • (2011) J Biol Chem , vol.286 , pp. 28019-28025
    • Zou, C.1    Ellis, B.M.2    Smith, R.M.3    Chen, B.B.4    Zhao, Y.5    Mallampalli, R.K.6
  • 154
    • 78951480982 scopus 로고    scopus 로고
    • LPS impairs phospholipid synthesis by triggering beta-transducin repeat-containing protein (beta-TrCP) - Mediated polyubiquitination and degradation of the surfactant enzyme acyl-CoA: Lysophosphatidylcholine acyltransferase I (LPCAT1)
    • ZOU C, BUTLER PL, COON TA, SMITH RM, HAMMEN G, ZHAO Y, CHEN BB, MALLAMPALLI RK. LPS impairs phospholipid synthesis by triggering beta-transducin repeat-containing protein (beta-TrCP) - mediated polyubiquitination and degradation of the surfactant enzyme acyl-CoA: lysophosphatidylcholine acyltransferase I (LPCAT1). J Biol Chem 2011;286:2719-2727.
    • (2011) J Biol Chem , vol.286 , pp. 2719-2727
    • Zou, C.1    Butler, P.L.2    Coon, T.A.3    Smith, R.M.4    Hammen, G.5    Zhao, Y.6    Chen, B.B.7    Mallampalli, R.K.8
  • 155
    • 80052773862 scopus 로고    scopus 로고
    • Cigarette smoke induces Akt protein degradation by the ubiquitin-proteasome system
    • KIM SY, LEE JH, HUH JW, RO JY, OH YM, LEE SD, AN S, LEE YS. Cigarette smoke induces Akt protein degradation by the ubiquitin-proteasome system. J Biol Chem 2011;286:31932-31943.
    • (2011) J Biol Chem , vol.286 , pp. 31932-31943
    • Kim, S.Y.1    Lee, J.H.2    Huh, J.W.3    Ro, J.Y.4    Oh, Y.M.5    Lee, S.D.6    An, S.7    Lee, Y.S.8
  • 156
    • 84856330202 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system and F-box proteins in pathogenic fungi
    • LIU TB, XUE C. The Ubiquitin-Proteasome System and F-box Proteins in Pathogenic Fungi. Mycobiology 2011;39:243-248.
    • (2011) Mycobiology , vol.39 , pp. 243-248
    • Liu, T.B.1    Xue, C.2
  • 158
    • 84864448811 scopus 로고    scopus 로고
    • Proteasome deubiquitinases as novel targets for cancer therapy
    • D'ARCY P, LINDER S. Proteasome deubiquitinases as novel targets for cancer therapy. Int J Biochem Cell Biol 2012;44:1729-1738.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1729-1738
    • D'Arcy, P.1    Linder, S.2
  • 159
    • 84860496378 scopus 로고    scopus 로고
    • The Fbw7 and beta-TRCP E3 ubiquitin ligases and their roles in tumorigenesis
    • LAU AW, FUKUSHIMA H, WEI W. The Fbw7 and beta-TRCP E3 ubiquitin ligases and their roles in tumorigenesis. Front Biosci 2012;17:2197-2212.
    • (2012) Front Biosci , vol.17 , pp. 2197-2212
    • Lau, A.W.1    Fukushima, H.2    Wei, W.3
  • 160
    • 84860516339 scopus 로고    scopus 로고
    • Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae
    • SINGH RK, GONZALEZ M, KABBAJ MH, GUNJAN A. Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae. PLoS One 2012;7:e36295.
    • (2012) PLoS One , vol.7 , pp. e36295
    • Singh, R.K.1    Gonzalez, M.2    Kabbaj, M.H.3    Gunjan, A.4
  • 161
    • 84863793933 scopus 로고    scopus 로고
    • A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
    • GATTI M, PINATO S, MASPERO E, SOFFIENTINI P, POLO S, PENENGO L. A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase. Cell Cycle 2012;11:2538-2544.
    • (2012) Cell Cycle , vol.11 , pp. 2538-2544
    • Gatti, M.1    Pinato, S.2    Maspero, E.3    Soffientini, P.4    Polo, S.5    Penengo, L.6
  • 162
    • 84867788817 scopus 로고    scopus 로고
    • Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer
    • CAO J, YAN Q. Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer. Front Oncol 2012;2:26.
    • (2012) Front Oncol , vol.2 , pp. 26
    • Cao, J.1    Yan, Q.2
  • 163
    • 84859259227 scopus 로고    scopus 로고
    • Histone ubiquitylation and chromatin dynamics
    • WRIGHT DE, WANG CY, KAO CF. Histone ubiquitylation and chromatin dynamics. Front Biosci 2012;7:1051-1078.
    • (2012) Front Biosci , vol.7 , pp. 1051-1078
    • Wright, D.E.1    Wang, C.Y.2    Kao, C.F.3
  • 165
    • 33947509939 scopus 로고    scopus 로고
    • Regulation of histone H2A and H2B ubiquitylation
    • OSLEY MA. Regulation of histone H2A and H2B ubiquitylation. Brief Funct Genomic Proteomic 2006;5:179-189.
    • (2006) Brief Funct Genomic Proteomic , vol.5 , pp. 179-189
    • Osley, M.A.1
  • 168
    • 77957354585 scopus 로고    scopus 로고
    • Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway
    • FAUCHER D, WELLINGER RJ. Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway. PLoS Genet 2010;6:e1001082.
    • (2010) PLoS Genet , vol.6 , pp. e1001082
    • Faucher, D.1    Wellinger, R.J.2
  • 169
    • 84861208532 scopus 로고    scopus 로고
    • Coupling of glucose deprivation with impaired histone H2B monoubiquitination in tumors
    • URASAKI Y, HEATH L, XU CW. Coupling of glucose deprivation with impaired histone H2B monoubiquitination in tumors. PLoS One 2012;7:e36775.
    • (2012) PLoS One , vol.7 , pp. e36775
    • Urasaki, Y.1    Heath, L.2    Xu, C.W.3


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