Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 6, 2012, Pages 1967-1972

  Lee, Ding Yu ^a   Lee, Chih I ^a   Lin, Ting Er ^a   Lim, Seh Hong ^a   Zhou, Jing ^b   Tseng, Ying Chih ^c   Chien, Shu ^b   Chiu, Jeng Jiann ^a,d  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CATHAY GENERAL HOSPITAL   (Taiwan)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Epigenetics; Mechanotransduction; Transcriptional regulation

Indexed keywords

BROXURIDINE; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 7; KRUPPEL LIKE FACTOR 2; MYOCYTE ENHANCER FACTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; VALPROIC ACID; VASCULAR CELL ADHESION MOLECULE 1;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA ARCH; AORTA STENOSIS; ARTICLE; CELL CULTURE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; NUCLEAR EXPORT SIGNAL; OSCILLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSATILE FLOW; RAT; SHEAR FLOW; SHEAR STRESS; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLATION; ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL PROLIFERATION; DOWN-REGULATION; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME INDUCTION; HISTONE DEACETYLASES; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MODELS, BIOLOGICAL; MYOGENIC REGULATORY FACTORS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RESPONSE ELEMENTS; RHEOLOGY; STRESS, MECHANICAL; TRANSCRIPTION FACTORS; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

RATTUS;

EID: 84863135417     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1121214109     Document Type: Article

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