Hypoxia-derived oxidative stress mediates epigenetic repression of PKCε gene in foetal rat hearts

Cardiovascular Research

Volumn 93, Issue 2, 2012, Pages 302-310

  Patterson, Andrew J ^a   Xiao, Daliao ^a   Xiong, Fuxia ^a   Dixon, Brandon ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epigenetic; Heart; Hypoxia; Oxidative stress; Protein kinase C

Indexed keywords

2 METHOXYESTRADIOL; ACETYLCYSTEINE; APOCYNIN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIFICIGUAT; MESSENGER RNA; PROTEIN KINASE C EPSILON; REACTIVE OXYGEN METABOLITE; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL NUCLEUS; CONTROLLED STUDY; CPG ISLAND; DISEASE PREDISPOSITION; DNA METHYLATION; EMBRYO; EPIGENETICS; FEMALE; FETUS; FETUS HEART; GENE REPRESSION; HEART MUSCLE CELL; HYPOXIA; ISCHEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; RAT;

ACETYLCYSTEINE; ANIMALS; ANOXIA; CYCLIC N-OXIDES; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL HEART; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYOCARDIAL REPERFUSION INJURY; NADPH OXIDASE; OXIDATIVE STRESS; PREGNANCY; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C-EPSILON; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPIN LABELS;

EID: 84862950110     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr322     Document Type: Article

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