Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells

Journal of Biological Chemistry

Volumn 282, Issue 16, 2007, Pages 12249-12259

  Lu, Rong ^a   Wang, Xia ^a   Chen, Zhao Fei ^a   Sun, Dan Feng ^a   Tian, Xiao Qing ^a   Fang, Jing Yuan ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NONE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CELL PROLIFERATION; DNA; METHYLATION; ONCOLOGY; RNA;

CELL NUCLEAR ANTIGENS; COLON CANCER CELLS; DNA METHYLATION; EXTRACELLULAR SIGNAL REGULATED KINASE;

ENZYMES;

DNA METHYLTRANSFERASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETOPHENONE DERIVATIVE; BENZOPYRAN DERIVATIVE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; ENZYME INHIBITOR; FLAVONOID; PRIMER DNA; ROTTLERIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; CHEMISTRY; COLON TUMOR; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; METABOLISM; MOLECULAR GENETICS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACETOPHENONES; BASE SEQUENCE; BENZOPYRANS; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA PRIMERS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MOLECULAR SEQUENCE DATA;

EID: 34249705328     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608525200     Document Type: Article

References (42)

1. Gao, Z., Gao, Z., Fields, J. Z., and Boman, B. M. (1999) Int. J. Cancer 82, 346-352
2. Rylova, S. N., Amalfitano, A., Persaud-Sawin, D. A., Guo, W. X., Chang, J., Jansen, P. J., Proia, A. D., and Boustany, R. M. (2002) Cancer Res. 62, 801-808
3. Shiraki, K., Tsuji, N., Shioda, T., Isselbacher, K. J., and Takahashi, H. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6420-6425
4. Scheinbart, L. S., Johnson, M. A., Gross, L. A., Edelstein, S. R., and Richardson, B. C. (1991) J. Rheumatol. 18, 530-534
5. Seger, R., and Krebs, E. G. (1995) FASEB J. 9, 726-735
6. Woods, D., Parry, D., Cherwinski, H., Bosch, E., Lees, E., and McMahon, M. (1997) Mol. Cell. Biol. 17, 5598-5611
7. Fang, J. Y., and Richardson, B. C. (2005) Lancet Oncol. 6, 322-327
8. Biro, T., Griger, Z., Kiss, E., Papp, H., Aleksza, M., Kovacs, I., Zeher, M., Bodolay, E., Csepany, T., Szucs, K., Gergely, P., Kovacs, L., Szegedi, G., and Sipka, S. (2004) Scand. J. Immunol. 60, 421-428
9. Hofmann, J. (2004) Curr. Cancer Drug. Targets 4, 125-146
10. Gschwendt, M. (1999) Eur. J. Biochem. 259, 555-564
11. Fang, J. Y., Lu, R., Mikovits, J. A., Cheng, Z. H., Zhu, H. Y., and Chen, Y. X. (2006) Cancer Lett. 233, 124-130
12. Laird, P. W., Jackson-Grusby, L., Fazeli, A., Dickinson, S. L., Jung, W. E., Li, E., Weinberg, R. A., and Jaenisch, R. (1995) Cell 81, 197-205
13. Esteller, M., Sparks, A., Toyota, M., Sanchez-Cespedes, M., Capella, G., Peinado, M. A., Gonzalez, S., Tarafa, G., Sidransky, D., Meltzer, S. J., Baylin, S. B., and Herman, J. G. (2000) Cancer Res. 60, 4366-4371
14. Jackson-Grusby, L., Beard, C., Possemato, R., Tudor, M., Fambrough, D., Csankovszki, G., Dausman, J., Lee, P., Wilson, C., Lander, E., and Jaenisch, R. (2001) Nat. Genet. 27, 31-39
15. Deng, C., Yang, J., Scott, J., Hanash, S., and Richardson, B. C. (1998) Biol. Chem. 379, 1113-1120
16. Deng, C., Kaplan, M. J., Yang, J., Ray, D., Zhang, Z., McCune, W. J., Hanash, S. M., and Richardson, B. C. (2001) Arthritis Rheum. 44, 397-407
17. Ramirez, T., Garcia-Montalvo, V., Wise, C., Cea-Olivares, R., Poirier, L. A., and Herrera, L. A. (2003) Mutat. Res. 528, 61-74
18. Gschwendt, M., Muller, H. J., Kielbassa, K., Zang, R., Kittstein, W., Rincke, G., and Marks, F. (1994) Biochem. Biophys. Res. Commun. 199, 93-98
19. Scanlan, M. J., Welt, S., Gordon, C. M., Chen, Y. T., Gure, A. O., Stockert, E., Jungbluth, A. A., Ritter, G., Jager, D., Jager, E., Knuth, A., and Old, L. J. (2002) Cancer Res. 62, 4041-4047
20. Xiong, Z., and Laird, P. W. (1997) Nucleic Acids Res. 25, 2532-2534
21. Fang, J. Y., Mikovits, J. A., Bagni, R., Petrow-Sadowski, C. L., and Ruscetti, F. W. (2001) J. Virol. 75, 9753-9761
22. Bender, C. M., Gonzalgo, M. L., Gonzales, F. A., Nguyen, C. T., Robertson, K. D., and Jones, P. A. (1999) Mol. Cell. Biol. 19, 6690-6698
23. Wu, S. J., Ng, L. T., and Lin, C. C. (2005) Life Sci. 77, 938-951
24. Troppmair, J., Bruder, J. T., Munoz, H., Lloyd, P. A., Kyriakis, J., Banerjee, P., Avruch, J., and Rapp, U. R. (1994) J. Biol. Chem. 269, 7030-7035
25. Taupin, D., and Podolsky, D. K. (1999) Gastroenterology 116, 1072-1080
26. Qi, X., Tang, J., Pramanik, R., Schultz, R. M., Shirasawa, S., Sasazuki, T., Han, J., and Chen, G. (2004) J. Biol. Chem. 279, 22138-22144
27. Zhang, X. M., Chen, J., Xia, Y. G., and Xu, Q. (2005) Cancer Chemother. Pharmacol. 55, 251-262
28. Chae, H. J., Park, K. M., Lee, G. Y., Jeong, G. S., Park, H. R., Kim, H. M., Chae, S. W., Yoo, S. K., and Kim, H. R. (2004) Acta Pharmacol. Sin. 25, 1372-1379
29. Lunghi, P., Costanzo, A., Levrero, M., and Bonati, A. (2004) Blood 104, 519-525
30. Liu, X., Yan, S., Zhou, T., Terada, Y., and Erikson, R. L. (2004) Oncogene 23, 763-776
31. Jakubikova, J., Sedlak, J., Bacon, J., Goldson, A., and Bao, Y. (2005) Int. J. Oncol. 27, 1449-1458
32. Jeon, H. K., Choi, S. U., and Jung, N. P. (2005) Cell Biol. Toxicol. 21, 115-125
33. Knibiehler, M., Goubin, F., Escalas, N., Jonsson, Z. O., Mazarguil, H., Hubscher, U., and Ducommun, B. (1996) FEBS Lett. 391, 66-70
34. Zhang, H., Xiong, Y., and Beach, D. (1993) Mol. Biol. Cell 4, 897-906
35. Enokida, H., Shiina, H., Igawa, M., Ogishima, T., Kawakami, T., Bassett, W. W., Anast, J. W., Li, L. C., Urakami, S., Terashima, M., Verma, M., Kawahara, M., Nakagawa, M., Kane, C. J., Carroll, P. R., and Dahiya, R. (2004) Cancer Res. 64, 5956-5962
36. Chuang, L. S., Ian, H. I., Koh, T. W., Ng, H. H., Xu, G., and Li, B. F. (1997) Science 277, 1996-2000
37. Iida, T., Suetake, I., Tajima, S., Morioka, H., Ohta, S., Obuse, C., and Tsurimoto, T. (2002) Genes Cells 7, 997-1007
38. Williams, T. M., Lee, H., Cheung, M. W., Cohen, A. W., Razani, B., Iyengar, P., Scherer, P. E., Pestell, R. G., and Lisanti, M. P. (2004) J. Biol. Chem. 279, 24745-24756
39. Kim, G. Y., Mercer, S. E., Ewton, D. Z., Yan, Z., Jin, K., and Friedman, E. (2002) J. Biol. Chem. 277, 29792-29802
40. McMillan, L., Butcher, S. K., Pongracz, J., and Lord, J. M. (2003) Br. J. Cancer 88, 748-753
41. Lin, S. Y., Liang, Y. C., Ho, Y. S., Tsai, S. H., Pan, S., and Lee, W. S. (2002) Mol. Carcinog. 35, 21-28
42. Zhu, H., Zhang, L., Wu, S., Teraishi, F., Davis, J. J., Jacob, D., and Fang, B. (2004) Oncogene 23, 4984-4992