메뉴 건너뛰기




Volumn 23, Issue 12, 2003, Pages 4056-4065

Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21Cip1 promoter

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DEPSIPEPTIDE; DNA BINDING PROTEIN; ETOPOSIDE; HISTONE DEACETYLASE; LUCIFERASE; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

EID: 0037642249     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.12.4056-4065.2003     Document Type: Article
Times cited : (230)

References (56)
  • 4
    • 0036532026 scopus 로고    scopus 로고
    • Histone modifications in transcriptional regulation
    • Berger, S. L. 2002. Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev. 12:142-148.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 142-148
    • Berger, S.L.1
  • 5
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird, A. 2002. DNA methylation patterns and epigenetic memory. Genes Dev. 16:6-21.
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 6
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression: Belts, braces, and chromatin
    • Bird, A. P., and A. P. Wolffe. 1999. Methylation-induced repression: belts, braces, and chromatin. Cell 99:451-454.
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 7
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron, E. E., K. E. Bachman, S. Myohanen, J. G. Herman, and S. B. Baylin. 1999. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21:103-107.
    • (1999) Nat. Genet. , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 9
    • 0030746884 scopus 로고    scopus 로고
    • Sp1 binding is inhibited by (m)Cp(m)CpG methylation
    • Clark, S. J., J. Harrison, and P. L. Molloy. 1997. Sp1 binding is inhibited by (m)Cp(m)CpG methylation. Gene 195:67-71.
    • (1997) Gene , vol.195 , pp. 67-71
    • Clark, S.J.1    Harrison, J.2    Molloy, P.L.3
  • 10
    • 0025294471 scopus 로고
    • CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
    • Comb, M., and H. M. Goodman. 1990. CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res. 18:3975-3982.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3975-3982
    • Comb, M.1    Goodman, H.M.2
  • 11
    • 0028340280 scopus 로고
    • Purification of CpG islands using a methylated DNA binding column
    • Cross, S. H., J. A. Charlton, X. Nan, and A. P. Bird. 1994. Purification of CpG islands using a methylated DNA binding column. Nat. Genet. 6:236-244.
    • (1994) Nat. Genet. , vol.6 , pp. 236-244
    • Cross, S.H.1    Charlton, J.A.2    Nan, X.3    Bird, A.P.4
  • 13
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 15
    • 0031975771 scopus 로고    scopus 로고
    • Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation
    • Fuentes-Panana, E. M., and P. D. Ling. 1998. Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation. J. Virol. 72:693-700.
    • (1998) J. Virol. , vol.72 , pp. 693-700
    • Fuentes-Panana, E.M.1    Ling, P.D.2
  • 16
    • 0033988813 scopus 로고    scopus 로고
    • DNA methyltransferase Dnmt1 associates with histone deacetylase activity
    • Fuks, F., W. A. Burgers, A. Brehm, L. Hughes-Davies, and T. Kouzarides. 2000. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat. Genet. 24:88-91.
    • (2000) Nat. Genet. , vol.24 , pp. 88-91
    • Fuks, F.1    Burgers, W.A.2    Brehm, A.3    Hughes-Davies, L.4    Kouzarides, T.5
  • 18
    • 0030798245 scopus 로고    scopus 로고
    • Histone acetylation in chromatin structure and transcription
    • Grunstein, M. 1997. Histone acetylation in chromatin structure and transcription. Nature 389:349-352.
    • (1997) Nature , vol.389 , pp. 349-352
    • Grunstein, M.1
  • 20
    • 0024083068 scopus 로고
    • Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated
    • Holler, M., G. Westin, J. Jiricny, and W. Schaffner. 1988. Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev. 2:1127-1135.
    • (1988) Genes Dev. , vol.2 , pp. 1127-1135
    • Holler, M.1    Westin, G.2    Jiricny, J.3    Schaffner, W.4
  • 21
    • 0027525970 scopus 로고
    • Studies of the DNA binding properties of histone H4 amino terminus: Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA
    • Hong, L., G. P. Schroth, H. R. Matthews, P. Yau, and E. M. Bradbury. 1993. Studies of the DNA binding properties of histone H4 amino terminus: thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA. J. Biol. Chem. 268:305-314.
    • (1993) J. Biol. Chem. , vol.268 , pp. 305-314
    • Hong, L.1    Schroth, G.P.2    Matthews, H.R.3    Yau, P.4    Bradbury, E.M.5
  • 22
    • 0032475868 scopus 로고    scopus 로고
    • Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPβ and Sp1
    • Hu, Z. Z., L. Zhuang, J. Meng, and M. L. Dufau. 1998. Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPβ and Sp1. J. Biol. Chem. 273:26225-26235.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26225-26235
    • Hu, Z.Z.1    Zhuang, L.2    Meng, J.3    Dufau, M.L.4
  • 23
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga, S. M., and W. Schaffner. 1989. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 3:612-619.
    • (1989) Genes Dev. , vol.3 , pp. 612-619
    • Iguchi-Ariga, S.M.1    Schaffner, W.2
  • 24
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones, P. A., and D. Takai. 2001. The role of DNA methylation in mammalian epigenetics. Science 293:1068-1070.
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 26
    • 0028289947 scopus 로고
    • Analysis of androgen receptor-DNA interactions with receptor proteins produced in insect cells
    • Kallio, P. J., J. J. Palvimo, M. Mehto, and O. A. Janne. 1994. Analysis of androgen receptor-DNA interactions with receptor proteins produced in insect cells. J. Biol. Chem. 269:11514-11522.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11514-11522
    • Kallio, P.J.1    Palvimo, J.J.2    Mehto, M.3    Janne, O.A.4
  • 27
    • 0033214910 scopus 로고    scopus 로고
    • Transcriptional regulation of rat cyclin D1 gene by CpG methylation status in promoter region
    • Kitazawa, S., R. Kitazawa, and S. Maeda. 1999. Transcriptional regulation of rat cyclin D1 gene by CpG methylation status in promoter region. J. Biol. Chem. 274:28787-28793.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28787-28793
    • Kitazawa, S.1    Kitazawa, R.2    Maeda, S.3
  • 28
    • 0033566127 scopus 로고    scopus 로고
    • Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
    • Mancini, D. N., S. M. Singh, T. K. Archer, and D. I. Rodenhiser. 1999. Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors. Oncogene 18:4108-4119.
    • (1999) Oncogene , vol.18 , pp. 4108-4119
    • Mancini, D.N.1    Singh, S.M.2    Archer, T.K.3    Rodenhiser, D.I.4
  • 32
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan, X., H. H. Ng, C. A. Johnson, C. D. Laherty, B. M. Turner, R. N. Eisenman, and A. Bird. 1998. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 33
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita, N., T. Fujita, A. Aoike, N. E. Osifchin, P. D. Robbins, and T. Sakai. 1993. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 8:1063-1067.
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 34
    • 0034699344 scopus 로고    scopus 로고
    • Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency
    • Periyasamy, S., S. Ammanamanchi, M. P. Tillekeratne, and M. G. Brattain. 2000. Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency. Oncogene 19:4660-4667.
    • (2000) Oncogene , vol.19 , pp. 4660-4667
    • Periyasamy, S.1    Ammanamanchi, S.2    Tillekeratne, M.P.3    Brattain, M.G.4
  • 35
    • 85047700334 scopus 로고    scopus 로고
    • DNA methylation, imprinting, and cancer
    • Plass, C., and P. D. Soloway. 2002. DNA methylation, imprinting, and cancer. Eur. J. Hum. Genet. 10:6-16.
    • (2002) Eur. J. Hum. Genet. , vol.10 , pp. 6-16
    • Plass, C.1    Soloway, P.D.2
  • 36
    • 0031768386 scopus 로고    scopus 로고
    • Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells
    • Rajgolikar, G., K. K. Chan, and H. C. Wang. 1998. Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells. Breast Cancer Res. Treat. 51:29-38.
    • (1998) Breast Cancer Res. Treat. , vol.51 , pp. 29-38
    • Rajgolikar, G.1    Chan, K.K.2    Wang, H.C.3
  • 37
    • 0033919595 scopus 로고    scopus 로고
    • DNMT1 forms a complex with Rb, E2F1, and HDAC1, and represses transcription from E2F-responsive promoters
    • Robertson, K. D., S. Ait-Si-Ali, T. Yokochi, P. A. Wade, P. L. Jones, and A. P. Wolffe. 2000. DNMT1 forms a complex with Rb, E2F1, and HDAC1, and represses transcription from E2F-responsive promoters. Nat. Genet. 25:338-342.
    • (2000) Nat. Genet. , vol.25 , pp. 338-342
    • Robertson, K.D.1    Ait-Si-Ali, S.2    Yokochi, T.3    Wade, P.A.4    Jones, P.L.5    Wolffe, A.P.6
  • 38
    • 0034092009 scopus 로고    scopus 로고
    • DNA methylation: Past, present, and future directions
    • Robertson, K. D., and P. A. Jones. 2000. DNA methylation: past, present, and future directions. Carcinogenesis 21:461-467.
    • (2000) Carcinogenesis , vol.21 , pp. 461-467
    • Robertson, K.D.1    Jones, P.A.2
  • 40
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    • Rountree, M. R., K. E. Bachman, and S. B. Baylin. 2000. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat. Genet. 25:269-277.
    • (2000) Nat. Genet. , vol.25 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 41
    • 0035962632 scopus 로고    scopus 로고
    • DNA methylation, chromatin inheritance, and cancer
    • Rountree, M. R., K. E. Bachman, J. G. Herman, and S. B. Baylin. 2001. DNA methylation, chromatin inheritance, and cancer. Oncogene 20:3156-3165.
    • (2001) Oncogene , vol.20 , pp. 3156-3165
    • Rountree, M.R.1    Bachman, K.E.2    Herman, J.G.3    Baylin, S.B.4
  • 42
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • Sherr, C. J. 2000. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res. 60:3689-3695.
    • (2000) Cancer Res. , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 43
    • 0034650338 scopus 로고    scopus 로고
    • Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells
    • Shin, J. Y., H. S. Kim, J. Park, J. B. Park, and J. Y. Lee. 2000. Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells. Cancer Res. 60:262-265.
    • (2000) Cancer Res. , vol.60 , pp. 262-265
    • Shin, J.Y.1    Kim, H.S.2    Park, J.3    Park, J.B.4    Lee, J.Y.5
  • 45
    • 0027325605 scopus 로고
    • Site-specific interaction of vaccinia virus topoisomerase I with base and sugar moieties in duplex DNA
    • Shuman, S., and J. Turner. 1993. Site-specific interaction of vaccinia virus topoisomerase I with base and sugar moieties in duplex DNA. J. Biol. Chem. 268:18943-18950.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18943-18950
    • Shuman, S.1    Turner, J.2
  • 46
    • 0033199611 scopus 로고    scopus 로고
    • Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor
    • Sowa, Y., T. Orita, S. Minamikawa-Hiranabe, T. Mizuno, H. Nomura, and T. Sakai. 1999. Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor. Cancer Res. 59:4266-4270.
    • (1999) Cancer Res. , vol.59 , pp. 4266-4270
    • Sowa, Y.1    Orita, T.2    Minamikawa-Hiranabe, S.3    Mizuno, T.4    Nomura, H.5    Sakai, T.6
  • 47
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl, K. 1998. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:599-606.
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 48
    • 0028966571 scopus 로고
    • Negative regulation of the vascular smooth muscle alpha-actin gene in fibroblasts and myoblasts: Disruption of enhancer function by sequence-specific single-stranded-DNA-binding proteins
    • Sun, S., E. S. Stoflet, J. G. Cogan, A. R. Strauch, and M. J. Getz. 1995. Negative regulation of the vascular smooth muscle alpha-actin gene in fibroblasts and myoblasts: disruption of enhancer function by sequence-specific single-stranded-DNA-binding proteins. Mol. Cell. Biol. 15:2429-2436.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2429-2436
    • Sun, S.1    Stoflet, E.S.2    Cogan, J.G.3    Strauch, A.R.4    Getz, M.J.5
  • 49
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate, P. H., and A. P. Bird. 1993. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev. 3:226-231.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 51
    • 0033964512 scopus 로고    scopus 로고
    • waf1/cip1 promoter activation induced by histone deacetylase inhibitor
    • waf1/cip1 promoter activation induced by histone deacetylase inhibitor. J. Biol. Chem. 275:1371-1376.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1371-1376
    • Xiao, H.1    Hasegawa, T.2    Isobe, K.3
  • 52
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong, Z., and P. W. Laird. 1997. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 25:2532-2534.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 53
    • 0035374458 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal
    • Young, J. I., and J. R. Smith. 2001. DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal. J. Biol. Chem. 276:19610-19616.
    • (2001) J. Biol. Chem. , vol.276 , pp. 19610-19616
    • Young, J.I.1    Smith, J.R.2
  • 54
    • 0033180082 scopus 로고    scopus 로고
    • Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
    • Zhang, Y., H. H. Ng, H. Erdjument-Bromage, P. Tempst, A. Bird, and D. Reinberg. 1999. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev. 13:1924-1935.
    • (1999) Genes Dev. , vol.13 , pp. 1924-1935
    • Zhang, Y.1    Ng, H.H.2    Erdjument-Bromage, H.3    Tempst, P.4    Bird, A.5    Reinberg, D.6
  • 56
    • 0035866353 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors
    • Zhu, W. G., R. R. Lakshmanan, M. D. Beal, and G. A. Otterson. 2001. DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. Cancer Res. 61:1327-1333.
    • (2001) Cancer Res. , vol.61 , pp. 1327-1333
    • Zhu, W.G.1    Lakshmanan, R.R.2    Beal, M.D.3    Otterson, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.